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Search of human proteins with 122937402
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937402 transmembrane protein 8C [Homo sapiens]
(221 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937402 transmembrane protein 8C [Homo sapiens] 457 e-129
gi|110556646 transmembrane protein 8B isoform a [Homo sapiens] 117 8e-27
gi|110556642 transmembrane protein 8B isoform a [Homo sapiens] 117 8e-27
gi|157676334 transmembrane protein 8 (five membrane-spanning dom... 116 2e-26
gi|27552764 transmembrane protein 8B isoform b [Homo sapiens] 40 0.002
gi|189458819 transferrin receptor [Homo sapiens] 33 0.19
gi|189458817 transferrin receptor [Homo sapiens] 33 0.19
gi|38348376 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltran... 28 4.7
gi|21536485 HIR histone cell cycle regulation defective homolog ... 28 8.1
>gi|122937402 transmembrane protein 8C [Homo sapiens]
Length = 221
Score = 457 bits (1175), Expect = e-129
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MGTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCF 60
MGTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCF
Sbjct: 1 MGTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCF 60
Query: 61 MRHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSG 120
MRHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSG
Sbjct: 61 MRHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSG 120
Query: 121 PIGTAILIIAAKWLQKMKEKKGLYPDKSVYTQQIGPGLCFGALALMLRFFFEDWDYTYVH 180
PIGTAILIIAAKWLQKMKEKKGLYPDKSVYTQQIGPGLCFGALALMLRFFFEDWDYTYVH
Sbjct: 121 PIGTAILIIAAKWLQKMKEKKGLYPDKSVYTQQIGPGLCFGALALMLRFFFEDWDYTYVH 180
Query: 181 SFYHCALAMSFVLLLPKVNKKAGSPGTPAKLDCSTLCCACV 221
SFYHCALAMSFVLLLPKVNKKAGSPGTPAKLDCSTLCCACV
Sbjct: 181 SFYHCALAMSFVLLLPKVNKKAGSPGTPAKLDCSTLCCACV 221
>gi|110556646 transmembrane protein 8B isoform a [Homo sapiens]
Length = 472
Score = 117 bits (293), Expect = 8e-27
Identities = 69/220 (31%), Positives = 110/220 (50%), Gaps = 3/220 (1%)
Query: 2 GTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCFM 61
G + LL LS+L FLP V +A + R+ +EA VY FT+FF +HAC+ PG+ V C M
Sbjct: 230 GFQLLSTLLLCLSNLMFLPPVVLAIRSRYVLEAAVYTFTMFFSTFYHACDQPGIVVFCIM 289
Query: 62 RHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSGP 121
+D+L++ G+ +S+WV+++A+A + + G + +++ + DR G GP
Sbjct: 290 DYDVLQFCDFLGSLMSVWVTVIAMARLQPVVKQVLYLLGAMLLSMALQLDRHGLWNLLGP 349
Query: 122 IGTAILIIAAKWLQKMKEKKGLYPDK-SVYTQQIGPGLCFGALALMLRFFFEDWD-YTYV 179
A+ I+A W + ++ YP + + PG A++L F E D Y Y+
Sbjct: 350 SLFALGILATAWTVRSVRRRHCYPPTWRRWLFYLCPGSLIAGSAVLLYAFVETRDNYFYI 409
Query: 180 HSFYHCALAMSFVLLL-PKVNKKAGSPGTPAKLDCSTLCC 218
HS +H +A S LL P+ G P C C
Sbjct: 410 HSIWHMLIAGSVGFLLPPRAKTDHGVPSGARARGCGYQLC 449
>gi|110556642 transmembrane protein 8B isoform a [Homo sapiens]
Length = 472
Score = 117 bits (293), Expect = 8e-27
Identities = 69/220 (31%), Positives = 110/220 (50%), Gaps = 3/220 (1%)
Query: 2 GTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCFM 61
G + LL LS+L FLP V +A + R+ +EA VY FT+FF +HAC+ PG+ V C M
Sbjct: 230 GFQLLSTLLLCLSNLMFLPPVVLAIRSRYVLEAAVYTFTMFFSTFYHACDQPGIVVFCIM 289
Query: 62 RHDILEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSGP 121
+D+L++ G+ +S+WV+++A+A + + G + +++ + DR G GP
Sbjct: 290 DYDVLQFCDFLGSLMSVWVTVIAMARLQPVVKQVLYLLGAMLLSMALQLDRHGLWNLLGP 349
Query: 122 IGTAILIIAAKWLQKMKEKKGLYPDK-SVYTQQIGPGLCFGALALMLRFFFEDWD-YTYV 179
A+ I+A W + ++ YP + + PG A++L F E D Y Y+
Sbjct: 350 SLFALGILATAWTVRSVRRRHCYPPTWRRWLFYLCPGSLIAGSAVLLYAFVETRDNYFYI 409
Query: 180 HSFYHCALAMSFVLLL-PKVNKKAGSPGTPAKLDCSTLCC 218
HS +H +A S LL P+ G P C C
Sbjct: 410 HSIWHMLIAGSVGFLLPPRAKTDHGVPSGARARGCGYQLC 449
>gi|157676334 transmembrane protein 8 (five membrane-spanning
domains) [Homo sapiens]
Length = 771
Score = 116 bits (290), Expect = 2e-26
Identities = 67/215 (31%), Positives = 109/215 (50%), Gaps = 2/215 (0%)
Query: 6 AKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFFVALHHACNGPGLSVLCFMRHDI 65
A LL TLS+L FL ++++ +R F +EA VY +T+FF +HAC+ PG +VLC + +D
Sbjct: 546 AATLLLTLSNLMFLAPIAVSVRRFFLVEASVYAYTMFFSTFYHACDQPGEAVLCILSYDT 605
Query: 66 LEYFSVYGTALSMWVSLMALADFDEPKRSTFVMFGVLTIAVRIYHDRWGYGVYSGPIGTA 125
L+Y G+ ++WV+++ +A + + G L IA+ + DR G GP A
Sbjct: 606 LQYCDFLGSGAAIWVTILCMARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFA 665
Query: 126 ILIIAAKWLQKMKEKKGLYPDK-SVYTQQIGPGLCFGALALMLRFFFEDWD-YTYVHSFY 183
+I+A+ W + ++ YP + + PG+ ++ + + D Y Y HS +
Sbjct: 666 FVIMASMWAYRCGHRRQCYPTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIW 725
Query: 184 HCALAMSFVLLLPKVNKKAGSPGTPAKLDCSTLCC 218
H LA S LLLP ++ A K C C
Sbjct: 726 HILLAGSAALLLPPPDQPAEPWACSQKFPCHYQIC 760
>gi|27552764 transmembrane protein 8B isoform b [Homo sapiens]
Length = 338
Score = 39.7 bits (91), Expect = 0.002
Identities = 20/42 (47%), Positives = 27/42 (64%)
Query: 2 GTLVAKLLLPTLSSLAFLPTVSIAAKRRFHMEAMVYLFTLFF 43
G + LL LS+L FLP V +A + R+ +EA VY FT+FF
Sbjct: 230 GFQLLSTLLLCLSNLMFLPPVVLAIRSRYVLEAAVYTFTMFF 271
>gi|189458819 transferrin receptor [Homo sapiens]
Length = 760
Score = 33.1 bits (74), Expect = 0.19
Identities = 15/46 (32%), Positives = 22/46 (47%)
Query: 104 IAVRIYHDRWGYGVYSGPIGTAILIIAAKWLQKMKEKKGLYPDKSV 149
+ V D WG G +GTA+L+ A+ M K G P +S+
Sbjct: 403 VVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSI 448
>gi|189458817 transferrin receptor [Homo sapiens]
Length = 760
Score = 33.1 bits (74), Expect = 0.19
Identities = 15/46 (32%), Positives = 22/46 (47%)
Query: 104 IAVRIYHDRWGYGVYSGPIGTAILIIAAKWLQKMKEKKGLYPDKSV 149
+ V D WG G +GTA+L+ A+ M K G P +S+
Sbjct: 403 VVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSI 448
>gi|38348376 UDP-GlcNAc:betaGal
beta-1,3-N-acetylglucosaminyltransferase 8 [Homo
sapiens]
Length = 397
Score = 28.5 bits (62), Expect = 4.7
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 114 GYGVYSGPIGTAILIIAAKWLQKMKEKKGLYPDKSVYTQQIGPGLCFGALALM 166
GY Y+ G I A WL + + +P + VYT GLC AL L+
Sbjct: 300 GYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYT-----GLCIRALGLV 347
>gi|21536485 HIR histone cell cycle regulation defective homolog A
[Homo sapiens]
Length = 1017
Score = 27.7 bits (60), Expect = 8.1
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 188 AMSFVLLLPKVNKKAGSPGTPAKLDCSTLCCA 219
A++ V PK+ KK G+ AK C CCA
Sbjct: 270 AVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCA 301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.141 0.459
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,231,340
Number of Sequences: 37866
Number of extensions: 322623
Number of successful extensions: 689
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 676
Number of HSP's gapped (non-prelim): 9
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.