Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 32483399
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32483399 p21-activated kinase 2 [Homo sapiens]
(524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32483399 p21-activated kinase 2 [Homo sapiens] 1047 0.0
gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens] 804 0.0
gi|189491753 p21-activated kinase 3 isoform a [Homo sapiens] 793 0.0
gi|189491751 p21-activated kinase 3 isoform a [Homo sapiens] 793 0.0
gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens] 793 0.0
gi|189491759 p21-activated kinase 3 isoform d [Homo sapiens] 783 0.0
gi|189491757 p21-activated kinase 3 isoform c [Homo sapiens] 781 0.0
gi|189491755 p21-activated kinase 3 isoform b [Homo sapiens] 775 0.0
gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens] 763 0.0
gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens] 358 9e-99
gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens] 358 9e-99
gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens] 322 7e-88
gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens] 322 7e-88
gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens] 322 7e-88
gi|191252782 p21-activated kinase 6 [Homo sapiens] 311 1e-84
gi|191252780 p21-activated kinase 6 [Homo sapiens] 311 1e-84
gi|9910476 p21-activated kinase 6 [Homo sapiens] 311 1e-84
gi|29826329 p21-activated kinase 7 [Homo sapiens] 307 1e-83
gi|24308191 p21-activated kinase 7 [Homo sapiens] 307 1e-83
gi|103471999 serine/threonine kinase 3 [Homo sapiens] 242 5e-64
gi|5454096 serine/threonine kinase 4 [Homo sapiens] 237 2e-62
gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo... 233 4e-61
gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens] 231 2e-60
gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens] 231 2e-60
gi|21361358 serine/threonine kinase 25 [Homo sapiens] 227 2e-59
gi|22035600 mitogen-activated protein kinase kinase kinase kinas... 207 2e-53
gi|15451902 mitogen-activated protein kinase kinase kinase kinas... 203 3e-52
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 201 2e-51
gi|145275208 myosin IIIA [Homo sapiens] 199 7e-51
gi|38570135 mitogen-activated protein kinase kinase kinase kinas... 198 1e-50
>gi|32483399 p21-activated kinase 2 [Homo sapiens]
Length = 524
Score = 1047 bits (2707), Expect = 0.0
Identities = 524/524 (100%), Positives = 524/524 (100%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT 60
MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT
Sbjct: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT 60
Query: 61 EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP 120
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
Sbjct: 61 EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP 120
Query: 121 QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP 180
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP
Sbjct: 121 QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP 180
Query: 181 PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV 240
PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV
Sbjct: 181 PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV 240
Query: 241 SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE 300
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
Sbjct: 241 SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE 300
Query: 301 LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH 360
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
Sbjct: 301 LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH 360
Query: 361 ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY 420
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
Sbjct: 361 ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY 420
Query: 421 GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC 480
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
Sbjct: 421 GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC 480
Query: 481 LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR 524
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR
Sbjct: 481 LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR 524
>gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens]
Length = 545
Score = 804 bits (2077), Expect = 0.0
Identities = 415/545 (76%), Positives = 464/545 (85%), Gaps = 23/545 (4%)
Query: 1 MSDNG-ELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSG 59
MS+NG +++DKPPAPP+R +ST+ G KD + NH KPLP PEEKK + +
Sbjct: 1 MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP 60
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKN 119
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITK EQKKN
Sbjct: 61 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN 120
Query: 120 PQAVLDVLKFYDSNTVK--QKYLSFTPPEKDGFPSGTPALNAKG-TEAPAV--VTEEEDD 174
PQAVLDVL+FY+S QKY+SFT + + S ALN K +E PAV V+E+EDD
Sbjct: 121 PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSN-ALNVKAVSETPAVPPVSEDEDD 179
Query: 175 DEE--TAPPVIAPRPDHTKSIYTRSVIDPVP---------APVGDSH-----VDGAAKSL 218
D++ T PPVIAPRP+HTKS+YTRSVI+P+P +P+ + D ++
Sbjct: 180 DDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNT 239
Query: 219 DKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIK 278
+KQKKK KM+DEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASGTV+TA DVA GQEVAIK
Sbjct: 240 EKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIK 299
Query: 279 QINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTET 338
Q+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVTET
Sbjct: 300 QMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTET 359
Query: 339 CMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQS 398
CMDE QIAAVCRECLQALEFLH+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPEQS
Sbjct: 360 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQS 419
Query: 399 KRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATN 458
KRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEM+EGEPPYLNENPLRALYLIATN
Sbjct: 420 KRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATN 479
Query: 459 GTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKE 518
GTPELQNPEKLS IFRDFLNRCLEMDVEKRGSAKELLQH FLK+AKPLSSLTPLI AAKE
Sbjct: 480 GTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKE 539
Query: 519 AMKSN 523
A K+N
Sbjct: 540 ATKNN 544
>gi|189491753 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 793 bits (2048), Expect = 0.0
Identities = 407/547 (74%), Positives = 464/547 (84%), Gaps = 29/547 (5%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKN 119
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFTG+PEQWARLLQTSNITKLEQKKN
Sbjct: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKN 115
Query: 120 PQAVLDVLKFYDSNTV--KQKYLSFTPPEKD--GFPSGTPALNAKGTEAPAV--VTEEED 173
PQAVLDVLKFYDS QKY+SFT +K G+ + P+ +E P V+EEED
Sbjct: 116 PQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEED 175
Query: 174 DDEETA------PPVIAPRPDHTKSIYTRSVIDPVPAPV-----------GDSHVDGAAK 216
++EE PPVIAPRP+HTKSIYTRSV++ + +P +++ +
Sbjct: 176 EEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYR 235
Query: 217 SLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVA 276
+ D+Q+KK+KMTDEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASGTV+TA D+A GQEVA
Sbjct: 236 NTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVA 295
Query: 277 IKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT 336
IKQ+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVT
Sbjct: 296 IKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT 355
Query: 337 ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
ETCMDE QIAAVCRECLQAL+FLH+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPE
Sbjct: 356 ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPE 415
Query: 397 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 456
QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA
Sbjct: 416 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 475
Query: 457 TNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAA 516
TNGTPELQNPE+LS +FRDFLNRCLEMDV++RGSAKELLQHPFLKLAKPLSSLTPLI+AA
Sbjct: 476 TNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAA 535
Query: 517 KEAMKSN 523
KEA+K++
Sbjct: 536 KEAIKNS 542
>gi|189491751 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 793 bits (2048), Expect = 0.0
Identities = 407/547 (74%), Positives = 464/547 (84%), Gaps = 29/547 (5%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKN 119
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFTG+PEQWARLLQTSNITKLEQKKN
Sbjct: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKN 115
Query: 120 PQAVLDVLKFYDSNTV--KQKYLSFTPPEKD--GFPSGTPALNAKGTEAPAV--VTEEED 173
PQAVLDVLKFYDS QKY+SFT +K G+ + P+ +E P V+EEED
Sbjct: 116 PQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEED 175
Query: 174 DDEETA------PPVIAPRPDHTKSIYTRSVIDPVPAPV-----------GDSHVDGAAK 216
++EE PPVIAPRP+HTKSIYTRSV++ + +P +++ +
Sbjct: 176 EEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYR 235
Query: 217 SLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVA 276
+ D+Q+KK+KMTDEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASGTV+TA D+A GQEVA
Sbjct: 236 NTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVA 295
Query: 277 IKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT 336
IKQ+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVT
Sbjct: 296 IKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT 355
Query: 337 ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
ETCMDE QIAAVCRECLQAL+FLH+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPE
Sbjct: 356 ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPE 415
Query: 397 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 456
QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA
Sbjct: 416 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 475
Query: 457 TNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAA 516
TNGTPELQNPE+LS +FRDFLNRCLEMDV++RGSAKELLQHPFLKLAKPLSSLTPLI+AA
Sbjct: 476 TNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAA 535
Query: 517 KEAMKSN 523
KEA+K++
Sbjct: 536 KEAIKNS 542
>gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 793 bits (2048), Expect = 0.0
Identities = 407/547 (74%), Positives = 464/547 (84%), Gaps = 29/547 (5%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKN 119
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFTG+PEQWARLLQTSNITKLEQKKN
Sbjct: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKN 115
Query: 120 PQAVLDVLKFYDSNTV--KQKYLSFTPPEKD--GFPSGTPALNAKGTEAPAV--VTEEED 173
PQAVLDVLKFYDS QKY+SFT +K G+ + P+ +E P V+EEED
Sbjct: 116 PQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEED 175
Query: 174 DDEETA------PPVIAPRPDHTKSIYTRSVIDPVPAPV-----------GDSHVDGAAK 216
++EE PPVIAPRP+HTKSIYTRSV++ + +P +++ +
Sbjct: 176 EEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYR 235
Query: 217 SLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVA 276
+ D+Q+KK+KMTDEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASGTV+TA D+A GQEVA
Sbjct: 236 NTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVA 295
Query: 277 IKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT 336
IKQ+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVT
Sbjct: 296 IKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT 355
Query: 337 ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
ETCMDE QIAAVCRECLQAL+FLH+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPE
Sbjct: 356 ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPE 415
Query: 397 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 456
QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA
Sbjct: 416 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 475
Query: 457 TNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAA 516
TNGTPELQNPE+LS +FRDFLNRCLEMDV++RGSAKELLQHPFLKLAKPLSSLTPLI+AA
Sbjct: 476 TNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAA 535
Query: 517 KEAMKSN 523
KEA+K++
Sbjct: 536 KEAIKNS 542
>gi|189491759 p21-activated kinase 3 isoform d [Homo sapiens]
Length = 559
Score = 783 bits (2022), Expect = 0.0
Identities = 407/562 (72%), Positives = 464/562 (82%), Gaps = 44/562 (7%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFT---------------GMPEQWAR 104
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFT G+PEQWAR
Sbjct: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWAR 115
Query: 105 LLQTSNITKLEQKKNPQAVLDVLKFYDSNTV--KQKYLSFTPPEKD--GFPSGTPALNAK 160
LLQTSNITKLEQKKNPQAVLDVLKFYDS QKY+SFT +K G+ + P+
Sbjct: 116 LLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKT 175
Query: 161 GTEAPAV--VTEEEDDDEETA------PPVIAPRPDHTKSIYTRSVIDPVPAPV------ 206
+E P V+EEED++EE PPVIAPRP+HTKSIYTRSV++ + +P
Sbjct: 176 ASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEV 235
Query: 207 -----GDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASG 261
+++ ++ D+Q+KK+KMTDEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASG
Sbjct: 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295
Query: 262 TVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFV 321
TV+TA D+A GQEVAIKQ+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+V
Sbjct: 296 TVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWV 355
Query: 322 VMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGS 381
VMEYLAGGSLTDVVTETCMDE QIAAVCRECLQAL+FLH+NQVIHRDIKSDN+LLGM+GS
Sbjct: 356 VMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGS 415
Query: 382 VKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEP 441
VKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEP
Sbjct: 416 VKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEP 475
Query: 442 PYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLK 501
PYLNENPLRALYLIATNGTPELQNPE+LS +FRDFLNRCLEMDV++RGSAKELLQHPFLK
Sbjct: 476 PYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLK 535
Query: 502 LAKPLSSLTPLIMAAKEAMKSN 523
LAKPLSSLTPLI+AAKEA+K++
Sbjct: 536 LAKPLSSLTPLIIAAKEAIKNS 557
>gi|189491757 p21-activated kinase 3 isoform c [Homo sapiens]
Length = 565
Score = 781 bits (2016), Expect = 0.0
Identities = 407/568 (71%), Positives = 464/568 (81%), Gaps = 50/568 (8%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFT---------------------GM 98
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFT G+
Sbjct: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQTSRPVTVASSQSEGKMGI 115
Query: 99 PEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTV--KQKYLSFTPPEKD--GFPSGT 154
PEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDS QKY+SFT +K G+ +
Sbjct: 116 PEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAH 175
Query: 155 PALNAKGTEAPAV--VTEEEDDDEETA------PPVIAPRPDHTKSIYTRSVIDPVPAPV 206
P+ +E P V+EEED++EE PPVIAPRP+HTKSIYTRSV++ + +P
Sbjct: 176 PSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPA 235
Query: 207 -----------GDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255
+++ ++ D+Q+KK+KMTDEEI+EKLR+IVS+GDPKKKYTR+EKI
Sbjct: 236 VPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKI 295
Query: 256 GQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLV 315
GQGASGTV+TA D+A GQEVAIKQ+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLV
Sbjct: 296 GQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV 355
Query: 316 GDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVL 375
GDEL+VVMEYLAGGSLTDVVTETCMDE QIAAVCRECLQAL+FLH+NQVIHRDIKSDN+L
Sbjct: 356 GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNIL 415
Query: 376 LGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIE 435
LGM+GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIE
Sbjct: 416 LGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIE 475
Query: 436 MVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELL 495
MVEGEPPYLNENPLRALYLIATNGTPELQNPE+LS +FRDFLNRCLEMDV++RGSAKELL
Sbjct: 476 MVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELL 535
Query: 496 QHPFLKLAKPLSSLTPLIMAAKEAMKSN 523
QHPFLKLAKPLSSLTPLI+AAKEA+K++
Sbjct: 536 QHPFLKLAKPLSSLTPLIIAAKEAIKNS 563
>gi|189491755 p21-activated kinase 3 isoform b [Homo sapiens]
Length = 580
Score = 775 bits (2001), Expect = 0.0
Identities = 407/583 (69%), Positives = 464/583 (79%), Gaps = 65/583 (11%)
Query: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFT----------------------- 96
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFT
Sbjct: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQTSRPVTVASSQSEGKMPD 115
Query: 97 -------------GMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTV--KQKYLS 141
G+PEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDS QKY+S
Sbjct: 116 LYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMS 175
Query: 142 FTPPEKD--GFPSGTPALNAKGTEAPAV--VTEEEDDDEETA------PPVIAPRPDHTK 191
FT +K G+ + P+ +E P V+EEED++EE PPVIAPRP+HTK
Sbjct: 176 FTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTK 235
Query: 192 SIYTRSVIDPVPAPV-----------GDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV 240
SIYTRSV++ + +P +++ ++ D+Q+KK+KMTDEEI+EKLR+IV
Sbjct: 236 SIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIV 295
Query: 241 SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE 300
S+GDPKKKYTR+EKIGQGASGTV+TA D+A GQEVAIKQ+NLQ+QPKKELIINEILVM+E
Sbjct: 296 SVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRE 355
Query: 301 LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH 360
KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVTETCMDE QIAAVCRECLQAL+FLH
Sbjct: 356 NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLH 415
Query: 361 ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY 420
+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
Sbjct: 416 SNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY 475
Query: 421 GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC 480
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPE+LS +FRDFLNRC
Sbjct: 476 GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRC 535
Query: 481 LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSN 523
LEMDV++RGSAKELLQHPFLKLAKPLSSLTPLI+AAKEA+K++
Sbjct: 536 LEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNS 578
>gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens]
Length = 553
Score = 763 bits (1969), Expect = 0.0
Identities = 393/518 (75%), Positives = 440/518 (84%), Gaps = 23/518 (4%)
Query: 1 MSDNG-ELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSG 59
MS+NG +++DKPPAPP+R +ST+ G KD + NH KPLP PEEKK + +
Sbjct: 1 MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP 60
Query: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKN 119
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITK EQKKN
Sbjct: 61 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN 120
Query: 120 PQAVLDVLKFYDSNTVK--QKYLSFTPPEKDGFPSGTPALNAKG-TEAPAV--VTEEEDD 174
PQAVLDVL+FY+S QKY+SFT + + S ALN K +E PAV V+E+EDD
Sbjct: 121 PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSN-ALNVKAVSETPAVPPVSEDEDD 179
Query: 175 DEE--TAPPVIAPRPDHTKSIYTRSVIDPVP---------APVGDSH-----VDGAAKSL 218
D++ T PPVIAPRP+HTKS+YTRSVI+P+P +P+ + D ++
Sbjct: 180 DDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNT 239
Query: 219 DKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIK 278
+KQKKK KM+DEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASGTV+TA DVA GQEVAIK
Sbjct: 240 EKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIK 299
Query: 279 QINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTET 338
Q+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVTET
Sbjct: 300 QMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTET 359
Query: 339 CMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQS 398
CMDE QIAAVCRECLQALEFLH+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPEQS
Sbjct: 360 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQS 419
Query: 399 KRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATN 458
KRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEM+EGEPPYLNENPLRALYLIATN
Sbjct: 420 KRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATN 479
Query: 459 GTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
GTPELQNPEKLS IFRDFLNRCLEMDVEKRGSAKELLQ
Sbjct: 480 GTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQ 517
>gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens]
Length = 438
Score = 358 bits (918), Expect = 9e-99
Identities = 196/458 (42%), Positives = 278/458 (60%), Gaps = 40/458 (8%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLD- 125
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ E + P+ ++D
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE-------ESARRPKPLVDP 56
Query: 126 -VLKFYDSNTVKQKYLSFTP--PEKDGFP-------SGTPALNAKGTEAPAVVTEEEDDD 175
+ K + P P G S P A+G +P V+ +
Sbjct: 57 ACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEP 116
Query: 176 EETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEK 235
+ APP P VP P G Q++ +++ E+
Sbjct: 117 Q-LAPPACTP------------AAPAVPGPPGPR---------SPQREPQRVSHEQFRAA 154
Query: 236 LRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEI 295
L+ +V GDP+ + KIG+G++G V AT + G+ VA+K+++L+KQ ++EL+ NE+
Sbjct: 155 LQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEV 214
Query: 296 LVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQA 355
++M++ ++ N+V +SYLVGDEL+VVME+L GG+LTD+VT T M+E QIAAVC LQA
Sbjct: 215 VIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQA 274
Query: 356 LEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV 415
L LHA VIHRDIKSD++LL +G VKL+DFGFCAQ++ E +R ++VGTPYWMAPE++
Sbjct: 275 LSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELI 334
Query: 416 TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRD 475
+R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A+ +I N P L+N K+SP +
Sbjct: 335 SRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKG 394
Query: 476 FLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
FL+R L D +R +A ELL+HPFL A P +S+ PL+
Sbjct: 395 FLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLM 432
>gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens]
Length = 438
Score = 358 bits (918), Expect = 9e-99
Identities = 196/458 (42%), Positives = 278/458 (60%), Gaps = 40/458 (8%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLD- 125
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ E + P+ ++D
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE-------ESARRPKPLVDP 56
Query: 126 -VLKFYDSNTVKQKYLSFTP--PEKDGFP-------SGTPALNAKGTEAPAVVTEEEDDD 175
+ K + P P G S P A+G +P V+ +
Sbjct: 57 ACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEP 116
Query: 176 EETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEK 235
+ APP P VP P G Q++ +++ E+
Sbjct: 117 Q-LAPPACTP------------AAPAVPGPPGPR---------SPQREPQRVSHEQFRAA 154
Query: 236 LRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEI 295
L+ +V GDP+ + KIG+G++G V AT + G+ VA+K+++L+KQ ++EL+ NE+
Sbjct: 155 LQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEV 214
Query: 296 LVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQA 355
++M++ ++ N+V +SYLVGDEL+VVME+L GG+LTD+VT T M+E QIAAVC LQA
Sbjct: 215 VIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQA 274
Query: 356 LEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV 415
L LHA VIHRDIKSD++LL +G VKL+DFGFCAQ++ E +R ++VGTPYWMAPE++
Sbjct: 275 LSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELI 334
Query: 416 TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRD 475
+R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A+ +I N P L+N K+SP +
Sbjct: 335 SRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKG 394
Query: 476 FLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
FL+R L D +R +A ELL+HPFL A P +S+ PL+
Sbjct: 395 FLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLM 432
>gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 322 bits (824), Expect = 7e-88
Identities = 167/362 (46%), Positives = 236/362 (65%), Gaps = 22/362 (6%)
Query: 152 SGTPALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHV 211
S P A+G +P V+ + + APP P VP P G
Sbjct: 246 SSRPPTRARGAPSPGVLGPHASEPQ-LAPPACTP------------AAPAVPGPPGPR-- 290
Query: 212 DGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVAL 271
Q++ +++ E+ L+ +V GDP+ + KIG+G++G V AT +
Sbjct: 291 -------SPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSS 343
Query: 272 GQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSL 331
G+ VA+K+++L+KQ ++EL+ NE+++M++ ++ N+V +SYLVGDEL+VVME+L GG+L
Sbjct: 344 GKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGAL 403
Query: 332 TDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCA 391
TD+VT T M+E QIAAVC LQAL LHA VIHRDIKSD++LL +G VKL+DFGFCA
Sbjct: 404 TDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCA 463
Query: 392 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRA 451
Q++ E +R ++VGTPYWMAPE+++R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A
Sbjct: 464 QVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKA 523
Query: 452 LYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTP 511
+ +I N P L+N K+SP + FL+R L D +R +A ELL+HPFL A P +S+ P
Sbjct: 524 MKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVP 583
Query: 512 LI 513
L+
Sbjct: 584 LM 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTS 109
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ S
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEES 46
>gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 322 bits (824), Expect = 7e-88
Identities = 167/362 (46%), Positives = 236/362 (65%), Gaps = 22/362 (6%)
Query: 152 SGTPALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHV 211
S P A+G +P V+ + + APP P VP P G
Sbjct: 246 SSRPPTRARGAPSPGVLGPHASEPQ-LAPPACTP------------AAPAVPGPPGPR-- 290
Query: 212 DGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVAL 271
Q++ +++ E+ L+ +V GDP+ + KIG+G++G V AT +
Sbjct: 291 -------SPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSS 343
Query: 272 GQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSL 331
G+ VA+K+++L+KQ ++EL+ NE+++M++ ++ N+V +SYLVGDEL+VVME+L GG+L
Sbjct: 344 GKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGAL 403
Query: 332 TDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCA 391
TD+VT T M+E QIAAVC LQAL LHA VIHRDIKSD++LL +G VKL+DFGFCA
Sbjct: 404 TDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCA 463
Query: 392 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRA 451
Q++ E +R ++VGTPYWMAPE+++R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A
Sbjct: 464 QVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKA 523
Query: 452 LYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTP 511
+ +I N P L+N K+SP + FL+R L D +R +A ELL+HPFL A P +S+ P
Sbjct: 524 MKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVP 583
Query: 512 LI 513
L+
Sbjct: 584 LM 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTS 109
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ S
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEES 46
>gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 322 bits (824), Expect = 7e-88
Identities = 167/362 (46%), Positives = 236/362 (65%), Gaps = 22/362 (6%)
Query: 152 SGTPALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHV 211
S P A+G +P V+ + + APP P VP P G
Sbjct: 246 SSRPPTRARGAPSPGVLGPHASEPQ-LAPPACTP------------AAPAVPGPPGPR-- 290
Query: 212 DGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVAL 271
Q++ +++ E+ L+ +V GDP+ + KIG+G++G V AT +
Sbjct: 291 -------SPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSS 343
Query: 272 GQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSL 331
G+ VA+K+++L+KQ ++EL+ NE+++M++ ++ N+V +SYLVGDEL+VVME+L GG+L
Sbjct: 344 GKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGAL 403
Query: 332 TDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCA 391
TD+VT T M+E QIAAVC LQAL LHA VIHRDIKSD++LL +G VKL+DFGFCA
Sbjct: 404 TDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCA 463
Query: 392 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRA 451
Q++ E +R ++VGTPYWMAPE+++R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A
Sbjct: 464 QVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKA 523
Query: 452 LYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTP 511
+ +I N P L+N K+SP + FL+R L D +R +A ELL+HPFL A P +S+ P
Sbjct: 524 MKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVP 583
Query: 512 LI 513
L+
Sbjct: 584 LM 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTS 109
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ S
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEES 46
>gi|191252782 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 311 bits (796), Expect = 1e-84
Identities = 168/391 (42%), Positives = 245/391 (62%), Gaps = 27/391 (6%)
Query: 141 SFTPPEKDGFPS------GTPALNAKGTEAPAVVTEEEDDDEE--TAP----------PV 182
SF PP+KD PS P+ GT +P ++ + TAP P
Sbjct: 290 SFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATGQLPGRSSPA 349
Query: 183 IAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSI 242
+PR H + I T ++ P V + G + +T E+ LR +V
Sbjct: 350 GSPRTWHAQ-ISTSNLYLPQDPTVAKGALAGEDTGV--------VTHEQFKAALRMVVDQ 400
Query: 243 GDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELK 302
GDP+ Y KIG+G++G V A + G++VA+K ++L+KQ ++EL+ NE+++M++ +
Sbjct: 401 GDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQ 460
Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN 362
+ N+V SYLVG+EL+V+ME+L GG+LTD+V++ ++E QIA VC LQAL +LHA
Sbjct: 461 HFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQ 520
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
VIHRDIKSD++LL ++G VKL+DFGFCAQI+ + KR ++VGTPYWMAPEV++R Y
Sbjct: 521 GVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYAT 580
Query: 423 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLE 482
+VDIWSLGIM IEMV+GEPPY +++P++A+ + + P+L+N K+SP+ RDFL R L
Sbjct: 581 EVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLV 640
Query: 483 MDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
D ++R +A+ELL HPFL L PLI
Sbjct: 641 RDPQERATAQELLDHPFLLQTGLPECLVPLI 671
Score = 57.8 bits (138), Expect = 2e-08
Identities = 22/44 (50%), Positives = 31/44 (70%)
Query: 65 KKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQT 108
+KK+K+RPEIS P +F+H +H FD G+F G+P QW +L T
Sbjct: 3 RKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDT 46
>gi|191252780 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 311 bits (796), Expect = 1e-84
Identities = 168/391 (42%), Positives = 245/391 (62%), Gaps = 27/391 (6%)
Query: 141 SFTPPEKDGFPS------GTPALNAKGTEAPAVVTEEEDDDEE--TAP----------PV 182
SF PP+KD PS P+ GT +P ++ + TAP P
Sbjct: 290 SFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATGQLPGRSSPA 349
Query: 183 IAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSI 242
+PR H + I T ++ P V + G + +T E+ LR +V
Sbjct: 350 GSPRTWHAQ-ISTSNLYLPQDPTVAKGALAGEDTGV--------VTHEQFKAALRMVVDQ 400
Query: 243 GDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELK 302
GDP+ Y KIG+G++G V A + G++VA+K ++L+KQ ++EL+ NE+++M++ +
Sbjct: 401 GDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQ 460
Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN 362
+ N+V SYLVG+EL+V+ME+L GG+LTD+V++ ++E QIA VC LQAL +LHA
Sbjct: 461 HFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQ 520
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
VIHRDIKSD++LL ++G VKL+DFGFCAQI+ + KR ++VGTPYWMAPEV++R Y
Sbjct: 521 GVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYAT 580
Query: 423 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLE 482
+VDIWSLGIM IEMV+GEPPY +++P++A+ + + P+L+N K+SP+ RDFL R L
Sbjct: 581 EVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLV 640
Query: 483 MDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
D ++R +A+ELL HPFL L PLI
Sbjct: 641 RDPQERATAQELLDHPFLLQTGLPECLVPLI 671
Score = 57.8 bits (138), Expect = 2e-08
Identities = 22/44 (50%), Positives = 31/44 (70%)
Query: 65 KKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQT 108
+KK+K+RPEIS P +F+H +H FD G+F G+P QW +L T
Sbjct: 3 RKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDT 46
>gi|9910476 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 311 bits (796), Expect = 1e-84
Identities = 168/391 (42%), Positives = 245/391 (62%), Gaps = 27/391 (6%)
Query: 141 SFTPPEKDGFPS------GTPALNAKGTEAPAVVTEEEDDDEE--TAP----------PV 182
SF PP+KD PS P+ GT +P ++ + TAP P
Sbjct: 290 SFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATGQLPGRSSPA 349
Query: 183 IAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSI 242
+PR H + I T ++ P V + G + +T E+ LR +V
Sbjct: 350 GSPRTWHAQ-ISTSNLYLPQDPTVAKGALAGEDTGV--------VTHEQFKAALRMVVDQ 400
Query: 243 GDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELK 302
GDP+ Y KIG+G++G V A + G++VA+K ++L+KQ ++EL+ NE+++M++ +
Sbjct: 401 GDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQ 460
Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN 362
+ N+V SYLVG+EL+V+ME+L GG+LTD+V++ ++E QIA VC LQAL +LHA
Sbjct: 461 HFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQ 520
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
VIHRDIKSD++LL ++G VKL+DFGFCAQI+ + KR ++VGTPYWMAPEV++R Y
Sbjct: 521 GVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYAT 580
Query: 423 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLE 482
+VDIWSLGIM IEMV+GEPPY +++P++A+ + + P+L+N K+SP+ RDFL R L
Sbjct: 581 EVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLV 640
Query: 483 MDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
D ++R +A+ELL HPFL L PLI
Sbjct: 641 RDPQERATAQELLDHPFLLQTGLPECLVPLI 671
Score = 57.8 bits (138), Expect = 2e-08
Identities = 22/44 (50%), Positives = 31/44 (70%)
Query: 65 KKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQT 108
+KK+K+RPEIS P +F+H +H FD G+F G+P QW +L T
Sbjct: 3 RKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDT 46
>gi|29826329 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 307 bits (787), Expect = 1e-83
Identities = 146/292 (50%), Positives = 216/292 (73%)
Query: 222 KKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQIN 281
++ ++++ E+ L+ +VS GDP++ + KIG+G++G V AT+ G++VA+K+++
Sbjct: 422 QQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMD 481
Query: 282 LQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMD 341
L+KQ ++EL+ NE+++M++ + N+V+ SYLVGDEL+VVME+L GG+LTD+VT T M+
Sbjct: 482 LRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMN 541
Query: 342 EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRS 401
E QIA VC L+AL +LH VIHRDIKSD++LL +G +KL+DFGFCAQ++ E KR
Sbjct: 542 EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK 601
Query: 402 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 461
++VGTPYWMAPEV++R YG +VDIWSLGIM IEM++GEPPY NE PL+A+ I + P
Sbjct: 602 SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP 661
Query: 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
+++ K+S + R FL+ L + +R +A+ELL HPFLKLA P S + PL+
Sbjct: 662 RVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLM 713
Score = 53.1 bits (126), Expect = 6e-07
Identities = 25/48 (52%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLL-QTSNITK 113
K+K++ EIS PS+FEH +H GFD +FTG+P+QW LL T+N K
Sbjct: 4 KKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPK 51
>gi|24308191 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 307 bits (787), Expect = 1e-83
Identities = 146/292 (50%), Positives = 216/292 (73%)
Query: 222 KKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQIN 281
++ ++++ E+ L+ +VS GDP++ + KIG+G++G V AT+ G++VA+K+++
Sbjct: 422 QQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMD 481
Query: 282 LQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMD 341
L+KQ ++EL+ NE+++M++ + N+V+ SYLVGDEL+VVME+L GG+LTD+VT T M+
Sbjct: 482 LRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMN 541
Query: 342 EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRS 401
E QIA VC L+AL +LH VIHRDIKSD++LL +G +KL+DFGFCAQ++ E KR
Sbjct: 542 EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK 601
Query: 402 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 461
++VGTPYWMAPEV++R YG +VDIWSLGIM IEM++GEPPY NE PL+A+ I + P
Sbjct: 602 SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP 661
Query: 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
+++ K+S + R FL+ L + +R +A+ELL HPFLKLA P S + PL+
Sbjct: 662 RVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLM 713
Score = 53.1 bits (126), Expect = 6e-07
Identities = 25/48 (52%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
Query: 67 KEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLL-QTSNITK 113
K+K++ EIS PS+FEH +H GFD +FTG+P+QW LL T+N K
Sbjct: 4 KKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPK 51
>gi|103471999 serine/threonine kinase 3 [Homo sapiens]
Length = 491
Score = 242 bits (618), Expect = 5e-64
Identities = 126/299 (42%), Positives = 186/299 (62%), Gaps = 12/299 (4%)
Query: 222 KKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQIN 281
K K K E+ + K P++ + EK+G+G+ G+VF A GQ VAIKQ+
Sbjct: 8 KSKLKKLSEDSLTK--------QPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVP 59
Query: 282 LQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETC 339
++ ++ II EI +M++ +P +V + SY +L++VMEY GS++D++
Sbjct: 60 VESDLQE--IIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT 117
Query: 340 MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK 399
+ E +IA + + L+ LE+LH + IHRDIK+ N+LL EG KL DFG Q+T +K
Sbjct: 118 LIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK 177
Query: 400 RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 459
R+T++GTP+WMAPEV+ Y DIWSLGI +IEM EG+PPY + +P+RA+++I TN
Sbjct: 178 RNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNP 237
Query: 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKE 518
P + PE S F DF+ +CL + E+R +A +LLQHPF+K AKP+S L LI A E
Sbjct: 238 PPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAME 296
>gi|5454096 serine/threonine kinase 4 [Homo sapiens]
Length = 487
Score = 237 bits (605), Expect = 2e-62
Identities = 122/299 (40%), Positives = 187/299 (62%), Gaps = 12/299 (4%)
Query: 222 KKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQIN 281
+++ K DE+ + K P++ + EK+G+G+ G+V+ A GQ VAIKQ+
Sbjct: 11 RRQLKKLDEDSLTK--------QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVP 62
Query: 282 LQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETC 339
++ ++ II EI +M++ +P++V + SY +L++VMEY GS++D++
Sbjct: 63 VESDLQE--IIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT 120
Query: 340 MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK 399
+ E +IA + + L+ LE+LH + IHRDIK+ N+LL EG KL DFG Q+T +K
Sbjct: 121 LTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK 180
Query: 400 RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 459
R+T++GTP+WMAPEV+ Y DIWSLGI AIEM EG+PPY + +P+RA+++I TN
Sbjct: 181 RNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNP 240
Query: 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKE 518
P + PE S F DF+ +CL E+R +A +LLQHPF++ AK +S L LI A +
Sbjct: 241 PPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMD 299
>gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo
sapiens]
Length = 416
Score = 233 bits (593), Expect = 4e-61
Identities = 125/275 (45%), Positives = 178/275 (64%), Gaps = 4/275 (1%)
Query: 241 SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMK 299
+I DP++ +T+ E+IG+G+ G VF D Q VAIK I+L++ + + E I EI V+
Sbjct: 16 NIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLS 75
Query: 300 ELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFL 359
+ + + + SYL G +L+++MEYL GGS D++ DE QIA + +E L+ L++L
Sbjct: 76 QCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYL 135
Query: 360 HANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA 419
H+ + IHRDIK+ NVLL +G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + A
Sbjct: 136 HSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSA 195
Query: 420 YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNR 479
Y K DIWSLGI AIE+ +GEPP + +P+R L+LI N P L + F++F++
Sbjct: 196 YDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVG--DFTKSFKEFIDA 253
Query: 480 CLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLI 513
CL D R +AKELL+H F+ K +K S LT LI
Sbjct: 254 CLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]
Length = 431
Score = 231 bits (588), Expect = 2e-60
Identities = 124/272 (45%), Positives = 174/272 (63%), Gaps = 4/272 (1%)
Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMKELK 302
DP++ +T+ EKIG+G+ G VF D + VAIK I+L++ + + E I EI V+ +
Sbjct: 19 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 78
Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN 362
+P + + SYL +L+++MEYL GGS D++ +DE QIA + RE L+ L++LH+
Sbjct: 79 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE 138
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
+ IHRDIK+ NVLL G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + AY
Sbjct: 139 KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS 198
Query: 423 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLE 482
K DIWSLGI AIE+ GEPP+ +P++ L+LI N P L+ S ++F+ CL
Sbjct: 199 KADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEG--NYSKPLKEFVEACLN 256
Query: 483 MDVEKRGSAKELLQHPF-LKLAKPLSSLTPLI 513
+ R +AKELL+H F L+ AK S LT LI
Sbjct: 257 KEPSFRPTAKELLKHKFILRNAKKTSYLTELI 288
>gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]
Length = 443
Score = 231 bits (588), Expect = 2e-60
Identities = 124/272 (45%), Positives = 174/272 (63%), Gaps = 4/272 (1%)
Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMKELK 302
DP++ +T+ EKIG+G+ G VF D + VAIK I+L++ + + E I EI V+ +
Sbjct: 31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 90
Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN 362
+P + + SYL +L+++MEYL GGS D++ +DE QIA + RE L+ L++LH+
Sbjct: 91 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE 150
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
+ IHRDIK+ NVLL G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + AY
Sbjct: 151 KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS 210
Query: 423 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLE 482
K DIWSLGI AIE+ GEPP+ +P++ L+LI N P L+ S ++F+ CL
Sbjct: 211 KADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEG--NYSKPLKEFVEACLN 268
Query: 483 MDVEKRGSAKELLQHPF-LKLAKPLSSLTPLI 513
+ R +AKELL+H F L+ AK S LT LI
Sbjct: 269 KEPSFRPTAKELLKHKFILRNAKKTSYLTELI 300
>gi|21361358 serine/threonine kinase 25 [Homo sapiens]
Length = 426
Score = 227 bits (578), Expect = 2e-59
Identities = 121/272 (44%), Positives = 175/272 (64%), Gaps = 4/272 (1%)
Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK-QPKKELIINEILVMKELK 302
DP++ +T+ ++IG+G+ G V+ D + VAIK I+L++ + + E I EI V+ +
Sbjct: 15 DPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 74
Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN 362
+P I + SYL +L+++MEYL GGS D++ ++E IA + RE L+ L++LH+
Sbjct: 75 SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSE 134
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
+ IHRDIK+ NVLL +G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + AY
Sbjct: 135 RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF 194
Query: 423 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLE 482
K DIWSLGI AIE+ +GEPP + +P+R L+LI N P L+ S F++F+ CL
Sbjct: 195 KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH--SKPFKEFVEACLN 252
Query: 483 MDVEKRGSAKELLQHPFL-KLAKPLSSLTPLI 513
D R +AKELL+H F+ + K S LT LI
Sbjct: 253 KDPRFRPTAKELLKHKFITRYTKKTSFLTELI 284
>gi|22035600 mitogen-activated protein kinase kinase kinase kinase 2
[Homo sapiens]
Length = 820
Score = 207 bits (526), Expect = 2e-53
Identities = 112/285 (39%), Positives = 172/285 (60%), Gaps = 6/285 (2%)
Query: 240 VSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMK 299
VS+ DP+ ++ +++G G G V+ A D + A+K + L + EI +++
Sbjct: 7 VSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILR 66
Query: 300 ELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEF 358
E ++PN+V ++ SYL D L++ ME+ GGSL ++ T ++E QIA VCRE L+ L
Sbjct: 67 ECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHH 126
Query: 359 LHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV--VT 416
LH+ IHRDIK N+LL ++G VKL DFG ++T +KR + +GTPYWMAPEV V
Sbjct: 127 LHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVE 186
Query: 417 RK-AYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG--TPELQNPEKLSPIF 473
RK Y D+W+LGI AIE+ E +PP + +P+RAL L++ + P+L++ + + F
Sbjct: 187 RKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNF 246
Query: 474 RDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKE 518
FL L + +KR +A++LLQHPF P + LT L+ A +
Sbjct: 247 HHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASD 291
>gi|15451902 mitogen-activated protein kinase kinase kinase kinase 3
[Homo sapiens]
Length = 894
Score = 203 bits (517), Expect = 3e-52
Identities = 114/263 (43%), Positives = 165/263 (62%), Gaps = 6/263 (2%)
Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN 303
+P++ + ++IG G G V+ A +V G+ AIK I L+ ++ EI++MK+ K+
Sbjct: 11 NPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKH 70
Query: 304 PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHAN 362
PNIV + SYL D+L++ ME+ GGSL D+ T + E QIA V RE LQ L +LH+
Sbjct: 71 PNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK 130
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV--VTRK-A 419
+HRDIK N+LL G VKL DFG AQIT +KR + +GTPYWMAPEV V RK
Sbjct: 131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGG 190
Query: 420 YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG--TPELQNPEKLSPIFRDFL 477
Y D+W++GI AIE+ E +PP + +P+RAL+L+ + P+L++ K S F F+
Sbjct: 191 YNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFV 250
Query: 478 NRCLEMDVEKRGSAKELLQHPFL 500
L + +KR +A++LLQHPF+
Sbjct: 251 KMALTKNPKKRPTAEKLLQHPFV 273
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 201 bits (510), Expect = 2e-51
Identities = 114/298 (38%), Positives = 171/298 (57%), Gaps = 26/298 (8%)
Query: 237 RTIVSIGDPKKKYTRYE----------------KIGQGASGTVFTATDVALGQEVAIKQI 280
R I +G KKK +YE ++G GA G V+ A + A K I
Sbjct: 7 RKIFKLGSEKKK-KQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVI 65
Query: 281 NLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TET 338
+ + + + E + EI ++ +PNIV LD++ + L++++E+ AGG++ V+ E
Sbjct: 66 DTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELER 125
Query: 339 CMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQS 398
+ E+QI VC++ L AL +LH N++IHRD+K+ N+L ++G +KL DFG A+ T
Sbjct: 126 PLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQ 185
Query: 399 KRSTMVGTPYWMAPEVV-----TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALY 453
+R + +GTPYWMAPEVV + Y K D+WSLGI IEM E EPP+ NP+R L
Sbjct: 186 RRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLL 245
Query: 454 LIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKL--AKPLSSL 509
IA + P L P + S F+DFL +CLE +V+ R + +LLQHPF+ + KP+ L
Sbjct: 246 KIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIREL 303
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 199 bits (505), Expect = 7e-51
Identities = 114/273 (41%), Positives = 161/273 (58%), Gaps = 17/273 (6%)
Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN 303
DP + E IG+G G VF + GQ+ A+K ++ +E I E ++K L +
Sbjct: 16 DPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEE-IEAEYNILKALSD 74
Query: 304 -PNIVNFLDSYLV-----GDELFVVMEYLAGGSLTDVVTETC-----MDEAQIAAVCREC 352
PN+V F Y GD+L++V+E +GGS+TD+V M E IA + E
Sbjct: 75 HPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEA 134
Query: 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAP 412
L L+ LH N+ IHRD+K +N+LL EG VKL DFG AQ+T + +R+T VGTP+WMAP
Sbjct: 135 LMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAP 194
Query: 413 EVVTRK-----AYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPE 467
EV+ + Y + D WSLGI AIE+ +G+PP + +P+RAL+ I N P+L+ PE
Sbjct: 195 EVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPE 254
Query: 468 KLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL 500
S F DF+++CL D EKR + ELLQH F+
Sbjct: 255 LWSAEFNDFISKCLTKDYEKRPTVSELLQHKFI 287
>gi|38570135 mitogen-activated protein kinase kinase kinase kinase 5
[Homo sapiens]
Length = 846
Score = 198 bits (503), Expect = 1e-50
Identities = 110/263 (41%), Positives = 159/263 (60%), Gaps = 6/263 (2%)
Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN 303
+P++ Y +++G G G V+ A +V G+ A+K I L+ LI EI ++KE K+
Sbjct: 15 NPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKH 74
Query: 304 PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHAN 362
NIV + SYL ++L++ MEY GGSL D+ T + E QIA VCRE LQ L +LH
Sbjct: 75 CNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTK 134
Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT---RKA 419
+HRDIK N+LL G VKL DFG A+IT +KR + +GTPYWMAPEV
Sbjct: 135 GKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGG 194
Query: 420 YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG--TPELQNPEKLSPIFRDFL 477
Y DIW++GI AIE+ E +PP + +P+RAL+L++ + P+L++ K S F +F+
Sbjct: 195 YNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFV 254
Query: 478 NRCLEMDVEKRGSAKELLQHPFL 500
L + +KR +A+ LL H F+
Sbjct: 255 KIALTKNPKKRPTAERLLTHTFV 277
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,258,798
Number of Sequences: 37866
Number of extensions: 1153258
Number of successful extensions: 6040
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 736
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 3392
Number of HSP's gapped (non-prelim): 1159
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.