Search of human proteins with 32483377

Search of human proteins with 32483377

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
         (238 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]                  482   e-136
gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]         471   e-133
gi|5453549 peroxiredoxin 4 [Homo sapiens]                             275   3e-74
gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]                  267   5e-72
gi|32455266 peroxiredoxin 1 [Homo sapiens]                            264   4e-71
gi|32455264 peroxiredoxin 1 [Homo sapiens]                            264   4e-71
gi|4505591 peroxiredoxin 1 [Homo sapiens]                             264   4e-71
gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo ...   176   2e-44
gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]                  118   5e-27
gi|4758638 peroxiredoxin 6 [Homo sapiens]                              64   9e-11
gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]      37   0.020
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot...    30   1.4  
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]       28   5.3  
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]       28   5.3  
gi|17998698 GATA binding protein 5 [Homo sapiens]                      28   9.1  

>gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
          Length = 238

 Score =  482 bits (1240), Expect = e-136
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAPYFKGTAVV 60
           MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAPYFKGTAVV
Sbjct: 1   MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAPYFKGTAVV 60

Query: 61  NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHF 120
           NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHF
Sbjct: 61  NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHF 120

Query: 121 SHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHL 180
           SHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHL
Sbjct: 121 SHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHL 180

Query: 181 SVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ 238
           SVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
Sbjct: 181 SVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ 238


>gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
          Length = 256

 Score =  471 bits (1211), Expect = e-133
 Identities = 238/256 (92%), Positives = 238/256 (92%), Gaps = 18/256 (7%)

Query: 1   MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQA--------- 51
           MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQA         
Sbjct: 1   MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC 60

Query: 52  ---------PYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN 102
                    PYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
Sbjct: 61  HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN 120

Query: 103 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG 162
           EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
Sbjct: 121 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG 180

Query: 163 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI 222
           LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
Sbjct: 181 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI 240

Query: 223 KPSPAASKEYFQKVNQ 238
           KPSPAASKEYFQKVNQ
Sbjct: 241 KPSPAASKEYFQKVNQ 256


>gi|5453549 peroxiredoxin 4 [Homo sapiens]
          Length = 271

 Score =  275 bits (703), Expect = 3e-74
 Identities = 128/190 (67%), Positives = 153/190 (80%)

Query: 48  SSQAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDV 107
           S  APY++GTAV++GEFK+L L D++GKYLV FFYPLDFTFVCPTEI+AF D+  EF  +
Sbjct: 82  SKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSI 141

Query: 108 NCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRG 167
           N EVVA SVDS F+HLAWINTPR+ GGLG + I LLSDLT QIS+DYGV LE SG  LRG
Sbjct: 142 NTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRG 201

Query: 168 LFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPA 227
           LFIID  G+++ +++NDLPVGRSV+ETLRLV+AFQY + HGEVCPA W P S TI P PA
Sbjct: 202 LFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPA 261

Query: 228 ASKEYFQKVN 237
              +YF K+N
Sbjct: 262 GKLKYFDKLN 271


>gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
          Length = 198

 Score =  267 bits (683), Expect = 5e-72
 Identities = 125/187 (66%), Positives = 152/187 (81%)

Query: 51  APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 110
           AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F  + CE
Sbjct: 12  APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71

Query: 111 VVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFI 170
           V+ VSVDS F+HLAWINTPRK GGLG +NI LL+D+T+++S DYGVL    G+A RGLFI
Sbjct: 72  VLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFI 131

Query: 171 IDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASK 230
           ID  GV++ ++VNDLPVGRSV+E LRLV+AFQY + HGEVCPA W P S TIKP+   SK
Sbjct: 132 IDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSK 191

Query: 231 EYFQKVN 237
           EYF K N
Sbjct: 192 EYFSKHN 198


>gi|32455266 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  264 bits (675), Expect = 4e-71
 Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)

Query: 51  APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 109
           AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF  +NC
Sbjct: 12  APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71

Query: 110 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 169
           +V+  SVDSHF HLAW+NTP+K GGLG MNI L+SD  + I++DYGVL    G++ RGLF
Sbjct: 72  QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131

Query: 170 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 229
           IID  G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP    S
Sbjct: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191

Query: 230 KEYFQK 235
           KEYF K
Sbjct: 192 KEYFSK 197


>gi|32455264 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  264 bits (675), Expect = 4e-71
 Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)

Query: 51  APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 109
           AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF  +NC
Sbjct: 12  APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71

Query: 110 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 169
           +V+  SVDSHF HLAW+NTP+K GGLG MNI L+SD  + I++DYGVL    G++ RGLF
Sbjct: 72  QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131

Query: 170 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 229
           IID  G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP    S
Sbjct: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191

Query: 230 KEYFQK 235
           KEYF K
Sbjct: 192 KEYFSK 197


>gi|4505591 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  264 bits (675), Expect = 4e-71
 Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)

Query: 51  APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 109
           AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF  +NC
Sbjct: 12  APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71

Query: 110 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 169
           +V+  SVDSHF HLAW+NTP+K GGLG MNI L+SD  + I++DYGVL    G++ RGLF
Sbjct: 72  QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131

Query: 170 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 229
           IID  G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP    S
Sbjct: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191

Query: 230 KEYFQK 235
           KEYF K
Sbjct: 192 KEYFSK 197


>gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
           sapiens]
          Length = 233

 Score =  176 bits (446), Expect = 2e-44
 Identities = 89/169 (52%), Positives = 114/169 (67%), Gaps = 24/169 (14%)

Query: 48  SSQAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDV 107
           S  APY++GTAV++GEFK+L L D++GKYLV FFYPLDFTFVCPTEI+AF D+  EF  +
Sbjct: 82  SKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSI 141

Query: 108 NCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRG 167
           N EVVA SVDS F+HLAW                        +S  Y    +   L L+G
Sbjct: 142 NTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDLLLKG 178

Query: 168 LFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCP-ANW 215
           LFIID  G+++ +++NDLPVGRSV+ETLRLV+AFQY + HGE  P ++W
Sbjct: 179 LFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSW 227


>gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
          Length = 142

 Score =  118 bits (295), Expect = 5e-27
 Identities = 52/75 (69%), Positives = 64/75 (85%)

Query: 51  APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 110
           AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F  + CE
Sbjct: 12  APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71

Query: 111 VVAVSVDSHFSHLAW 125
           V+ VSVDS F+HLAW
Sbjct: 72  VLGVSVDSQFTHLAW 86


>gi|4758638 peroxiredoxin 6 [Homo sapiens]
          Length = 224

 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 52/196 (26%), Positives = 89/196 (45%), Gaps = 15/196 (7%)

Query: 51  APYFKGTAVVNGEFKDLSLDDFKG-KYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 109
           AP F+    V      +   DF G  + +LF +P DFT VC TE+   +  A EF   N 
Sbjct: 11  APNFEANTTVGR----IRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNV 66

Query: 110 EVVAVSVDSHFSHLAW---INTPRKNGGLGHMNIALLSDLTKQISRDYGVL------LEG 160
           +++A+S+DS   HLAW   IN          +   ++ D  ++++   G+L       +G
Sbjct: 67  KLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKG 126

Query: 161 SGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSP 220
             +  R +F+  P+  +K   +     GR+ +E LR+V + Q         P +W  D  
Sbjct: 127 MPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDW-KDGD 185

Query: 221 TIKPSPAASKEYFQKV 236
           ++   P   +E  +K+
Sbjct: 186 SVMVLPTIPEEEAKKL 201


>gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]
          Length = 137

 Score = 36.6 bits (83), Expect = 0.020
 Identities = 18/48 (37%), Positives = 27/48 (56%)

Query: 78  VLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAW 125
           +LF +P D   VC  E+   +  A EF   N +++A++ DS   HLAW
Sbjct: 34  ILFSHPRDSKPVCTMELGRAAKLAPEFTKSNVKLIALATDSAEDHLAW 81


>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
           [Homo sapiens]
          Length = 431

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 5/46 (10%)

Query: 94  IVAFSDKANEFHDV--NCEVVAVSV---DSHFSHLAWINTPRKNGG 134
           +V+ S  +NE H V  NC+ +       + +FS++ W N P+K GG
Sbjct: 14  VVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGG 59


>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
          Length = 765

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 10/43 (23%)

Query: 186 PVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAA 228
           PV  SVEE          +   GE  PA   P+SPT  P PAA
Sbjct: 719 PVPPSVEE----------IPVPGEAVPAPTPPESPTPHPPPAA 751


>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
          Length = 766

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 10/43 (23%)

Query: 186 PVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAA 228
           PV  SVEE          +   GE  PA   P+SPT  P PAA
Sbjct: 720 PVPPSVEE----------IPVPGEAVPAPTPPESPTPHPPPAA 752


>gi|17998698 GATA binding protein 5 [Homo sapiens]
          Length = 397

 Score = 27.7 bits (60), Expect = 9.1
 Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 10/74 (13%)

Query: 15  RHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAPYFKGTAVVNGEFKDLSLDDFKG 74
           R+ SA P  +++T +    +  + SL + +C G S AP   G             D    
Sbjct: 308 RNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQ----------EDDSLAP 357

Query: 75  KYLVLFFYPLDFTF 88
            +L   F P DF F
Sbjct: 358 GHLEFKFEPEDFAF 371


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,773,385
Number of Sequences: 37866
Number of extensions: 369032
Number of successful extensions: 760
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 746
Number of HSP's gapped (non-prelim): 15
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.