Search of human proteins with 32189392

Search of human proteins with 32189392

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
         (198 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]                  406   e-114
gi|32455266 peroxiredoxin 1 [Homo sapiens]                            332   2e-91
gi|32455264 peroxiredoxin 1 [Homo sapiens]                            332   2e-91
gi|4505591 peroxiredoxin 1 [Homo sapiens]                             332   2e-91
gi|5453549 peroxiredoxin 4 [Homo sapiens]                             291   2e-79
gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]         267   4e-72
gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]                  267   4e-72
gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo ...   193   9e-50
gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]                  179   1e-45
gi|4758638 peroxiredoxin 6 [Homo sapiens]                              81   7e-16
gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]      34   0.071
gi|17572807 ropporin 1-like [Homo sapiens]                             33   0.12 
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                     27   8.7  

>gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
          Length = 198

 Score =  406 bits (1043), Expect = e-114
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60
           MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN
Sbjct: 1   MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60

Query: 61  RAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKT 120
           RAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKT
Sbjct: 61  RAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKT 120

Query: 121 DEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS 180
           DEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS
Sbjct: 121 DEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS 180

Query: 181 DTIKPNVDDSKEYFSKHN 198
           DTIKPNVDDSKEYFSKHN
Sbjct: 181 DTIKPNVDDSKEYFSKHN 198


>gi|32455266 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  332 bits (850), Expect = 2e-91
 Identities = 154/197 (78%), Positives = 180/197 (91%), Gaps = 1/197 (0%)

Query: 1   MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59
           M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 60  NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK 119
           +RAE+F+KL C+V+G SVDS F HLAW+NTP+K+GGLGP+NIPL++D  R +++DYGVLK
Sbjct: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120

Query: 120 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG 179
            DEGI++RGLFIID KG+LRQITVNDLPVGRSVDE LRLVQAFQ+TD+HGEVCPAGWKPG
Sbjct: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180

Query: 180 SDTIKPNVDDSKEYFSK 196
           SDTIKP+V  SKEYFSK
Sbjct: 181 SDTIKPDVQKSKEYFSK 197


>gi|32455264 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  332 bits (850), Expect = 2e-91
 Identities = 154/197 (78%), Positives = 180/197 (91%), Gaps = 1/197 (0%)

Query: 1   MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59
           M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 60  NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK 119
           +RAE+F+KL C+V+G SVDS F HLAW+NTP+K+GGLGP+NIPL++D  R +++DYGVLK
Sbjct: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120

Query: 120 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG 179
            DEGI++RGLFIID KG+LRQITVNDLPVGRSVDE LRLVQAFQ+TD+HGEVCPAGWKPG
Sbjct: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180

Query: 180 SDTIKPNVDDSKEYFSK 196
           SDTIKP+V  SKEYFSK
Sbjct: 181 SDTIKPDVQKSKEYFSK 197


>gi|4505591 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  332 bits (850), Expect = 2e-91
 Identities = 154/197 (78%), Positives = 180/197 (91%), Gaps = 1/197 (0%)

Query: 1   MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59
           M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 60  NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK 119
           +RAE+F+KL C+V+G SVDS F HLAW+NTP+K+GGLGP+NIPL++D  R +++DYGVLK
Sbjct: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120

Query: 120 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG 179
            DEGI++RGLFIID KG+LRQITVNDLPVGRSVDE LRLVQAFQ+TD+HGEVCPAGWKPG
Sbjct: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180

Query: 180 SDTIKPNVDDSKEYFSK 196
           SDTIKP+V  SKEYFSK
Sbjct: 181 SDTIKPDVQKSKEYFSK 197


>gi|5453549 peroxiredoxin 4 [Homo sapiens]
          Length = 271

 Score =  291 bits (746), Expect = 2e-79
 Identities = 136/193 (70%), Positives = 162/193 (83%)

Query: 6   ARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDF 65
           A+I KPAP ++ TAV+DG FKE+KL+DY+GKY+V FFYPLDFTFVCPTEIIAF +R E+F
Sbjct: 79  AKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEF 138

Query: 66  RKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIA 125
           R +  EV+  SVDSQFTHLAWINTPR++GGLGP+ IPLL+D+T ++S+DYGV   D G  
Sbjct: 139 RSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHT 198

Query: 126 YRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKP 185
            RGLFIID KG+LRQIT+NDLPVGRSVDE LRLVQAFQYTD+HGEVCPAGWKPGS+TI P
Sbjct: 199 LRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIP 258

Query: 186 NVDDSKEYFSKHN 198
           +     +YF K N
Sbjct: 259 DPAGKLKYFDKLN 271


>gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
          Length = 256

 Score =  267 bits (683), Expect = 4e-72
 Identities = 125/187 (66%), Positives = 152/187 (81%)

Query: 12  APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71
           AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F  + CE
Sbjct: 69  APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 128

Query: 72  VLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFI 131
           V+ VSVDS F+HLAWINTPRK GGLG +NI LL+D+T+++S DYGVL    G+A RGLFI
Sbjct: 129 VVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFI 188

Query: 132 IDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSK 191
           ID  GV++ ++VNDLPVGRSV+E LRLV+AFQY + HGEVCPA W P S TIKP+   SK
Sbjct: 189 IDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASK 248

Query: 192 EYFSKHN 198
           EYF K N
Sbjct: 249 EYFQKVN 255


>gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
          Length = 238

 Score =  267 bits (683), Expect = 4e-72
 Identities = 125/187 (66%), Positives = 152/187 (81%)

Query: 12  APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71
           AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F  + CE
Sbjct: 51  APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 110

Query: 72  VLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFI 131
           V+ VSVDS F+HLAWINTPRK GGLG +NI LL+D+T+++S DYGVL    G+A RGLFI
Sbjct: 111 VVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFI 170

Query: 132 IDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSK 191
           ID  GV++ ++VNDLPVGRSV+E LRLV+AFQY + HGEVCPA W P S TIKP+   SK
Sbjct: 171 IDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASK 230

Query: 192 EYFSKHN 198
           EYF K N
Sbjct: 231 EYFQKVN 237


>gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
           sapiens]
          Length = 233

 Score =  193 bits (490), Expect = 9e-50
 Identities = 101/173 (58%), Positives = 120/173 (69%), Gaps = 24/173 (13%)

Query: 6   ARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDF 65
           A+I KPAP ++ TAV+DG FKE+KL+DY+GKY+V FFYPLDFTFVCPTEIIAF +R E+F
Sbjct: 79  AKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEF 138

Query: 66  RKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIA 125
           R +  EV+  SVDSQFTHLAW                        +S  Y   K    + 
Sbjct: 139 RSINTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDLL 175

Query: 126 YRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCP-AGWK 177
            +GLFIID KG+LRQIT+NDLPVGRSVDE LRLVQAFQYTD+HGE  P + WK
Sbjct: 176 LKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228


>gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
          Length = 142

 Score =  179 bits (454), Expect = 1e-45
 Identities = 88/94 (93%), Positives = 90/94 (95%), Gaps = 1/94 (1%)

Query: 1  MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60
          MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN
Sbjct: 1  MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60

Query: 61 RAEDFRKLGCEVLGVSVDSQFTHLAWINT-PRKE 93
          RAEDFRKLGCEVLGVSVDSQFTHLAW    P++E
Sbjct: 61 RAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94


>gi|4758638 peroxiredoxin 6 [Homo sapiens]
          Length = 224

 Score = 80.9 bits (198), Expect = 7e-16
 Identities = 63/206 (30%), Positives = 100/206 (48%), Gaps = 17/206 (8%)

Query: 4   GNARIGKPAPDFKATAVVDGAFKEVKLSDYKG-KYVVLFFYPLDFTFVCPTEIIAFSNRA 62
           G   +G  AP+F+A   V      ++  D+ G  + +LF +P DFT VC TE+   +  A
Sbjct: 3   GGLLLGDVAPNFEANTTVG----RIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLA 58

Query: 63  EDFRKLGCEVLGVSVDSQFTHLAW---INTPRKEGGLGPLNIPLLADVTRRLSEDYGVL- 118
            +F K   +++ +S+DS   HLAW   IN    E     L  P++ D  R L+   G+L 
Sbjct: 59  PEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLD 118

Query: 119 ---KTDEG--IAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCP 173
              K ++G  +  R +F+      L+   +     GR+ DE LR+V + Q T E     P
Sbjct: 119 PAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATP 178

Query: 174 AGWKPG-SDTIKPNV--DDSKEYFSK 196
             WK G S  + P +  +++K+ F K
Sbjct: 179 VDWKDGDSVMVLPTIPEEEAKKLFPK 204


>gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]
          Length = 137

 Score = 34.3 bits (77), Expect = 0.071
 Identities = 16/48 (33%), Positives = 26/48 (54%)

Query: 39 VLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAW 86
          +LF +P D   VC  E+   +  A +F K   +++ ++ DS   HLAW
Sbjct: 34 ILFSHPRDSKPVCTMELGRAAKLAPEFTKSNVKLIALATDSAEDHLAW 81


>gi|17572807 ropporin 1-like [Homo sapiens]
          Length = 230

 Score = 33.5 bits (75), Expect = 0.12
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 64  DFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTR---RLSEDYGVLKT 120
           +F  LGC +LG S+++   HL  I T   EGG   +     + V R   RL  D   L+T
Sbjct: 128 NFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDSDVSPLET 187

Query: 121 DEGIA 125
           +  +A
Sbjct: 188 ESYLA 192


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score = 27.3 bits (59), Expect = 8.7
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 11/53 (20%)

Query: 145 DLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKH 197
           D+ +G   +EAL   QA          CP GW P S+  K   DD  +  S+H
Sbjct: 947 DICLGLHTEEALCATQA----------CPEGWSPWSEWSK-CTDDGAQSRSRH 988


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.140    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,612,361
Number of Sequences: 37866
Number of extensions: 318726
Number of successful extensions: 528
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 511
Number of HSP's gapped (non-prelim): 13
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.