Search of human proteins with 31563378

Search of human proteins with 31563378

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31563378 eukaryotic translation initiation factor 6 isoform
a [Homo sapiens]
         (245 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31563378 eukaryotic translation initiation factor 6 isoform a...   487   e-138
gi|4504771 eukaryotic translation initiation factor 6 isoform a ...   487   e-138
gi|31563374 eukaryotic translation initiation factor 6 isoform c...   270   6e-73
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]              32   0.66 
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]              32   0.66 
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    30   1.5  
gi|124430752 kinesin family member 26B [Homo sapiens]                  30   1.5  
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]                      29   3.3  
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]                    29   4.3  
gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens]     29   4.3  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           29   4.3  
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                 28   7.3  

>gi|31563378 eukaryotic translation initiation factor 6 isoform a
           [Homo sapiens]
          Length = 245

 Score =  487 bits (1254), Expect = e-138
 Identities = 245/245 (100%), Positives = 245/245 (100%)

Query: 1   MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 60
           MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG
Sbjct: 1   MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 60

Query: 61  RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 120
           RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD
Sbjct: 61  RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 120

Query: 121 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 180
           LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP
Sbjct: 121 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 180

Query: 181 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 240
           LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL
Sbjct: 181 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 240

Query: 241 IDSLT 245
           IDSLT
Sbjct: 241 IDSLT 245


>gi|4504771 eukaryotic translation initiation factor 6 isoform a
           [Homo sapiens]
          Length = 245

 Score =  487 bits (1254), Expect = e-138
 Identities = 245/245 (100%), Positives = 245/245 (100%)

Query: 1   MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 60
           MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG
Sbjct: 1   MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 60

Query: 61  RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 120
           RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD
Sbjct: 61  RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 120

Query: 121 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 180
           LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP
Sbjct: 121 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 180

Query: 181 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 240
           LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL
Sbjct: 181 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 240

Query: 241 IDSLT 245
           IDSLT
Sbjct: 241 IDSLT 245


>gi|31563374 eukaryotic translation initiation factor 6 isoform c
           [Homo sapiens]
          Length = 226

 Score =  270 bits (691), Expect = 6e-73
 Identities = 167/259 (64%), Positives = 175/259 (67%), Gaps = 47/259 (18%)

Query: 1   MAVRASFENNCEIGCFAKLTNTYCLVAI---------GGSENFYSVFEGELSDTIPVVHA 51
           MAVRASFENNCEIGCFAKLTNTYCLVAI         GGS   Y   E            
Sbjct: 1   MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYRCGGSPGAYGGGE------------ 48

Query: 52  SIAGCRIIGRMCVG----NRHGLLVPNNTTDQELQHIRNSLP-DTVQIRRVEERLSALGN 106
           + AG +  G   V       H + VP   +       R S P  +    R+    ++ G 
Sbjct: 49  ACAGVKSSGSGRVPAPLPRHHRVHVPTVCS-------RASSPIPSPWCTRLSPAAASSGA 101

Query: 107 VTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTS 166
                            ETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTS
Sbjct: 102 CVW--------------ETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTS 147

Query: 167 IEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNE 226
           IEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNE
Sbjct: 148 IEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNE 207

Query: 227 AQPSTIATSMRDSLIDSLT 245
           AQPSTIATSMRDSLIDSLT
Sbjct: 208 AQPSTIATSMRDSLIDSLT 226


>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
          Length = 855

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%)

Query: 69  GLLVPNNTTDQELQHIRNSLPDTVQ-IRRVEERLSALGNVTTCNDYVALVHPDLDRETEE 127
           GLL     T ++L+H R SL +  + + R+ E LSAL  +    +    +  + DR++ E
Sbjct: 361 GLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHE 420


>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
          Length = 824

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%)

Query: 69  GLLVPNNTTDQELQHIRNSLPDTVQ-IRRVEERLSALGNVTTCNDYVALVHPDLDRETEE 127
           GLL     T ++L+H R SL +  + + R+ E LSAL  +    +    +  + DR++ E
Sbjct: 361 GLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHE 420


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 16/129 (12%)

Query: 77  TDQELQHIRNSLPDTVQIRRVEERLS--ALGNVTTCNDYVALVHPDLDRETEEILADVLK 134
           T+ EL      L D  +   + E+ +  A G+V   N  + LV  +LDR  E +   + K
Sbjct: 53  TEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQK 112

Query: 135 VEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELS----SLLQVPLVAGTVNRGS 190
           +E   +  AD+         S +G  V    +++D++++      L +   +A   +R  
Sbjct: 113 LEE-AEKAADE---------SERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162

Query: 191 EVIAAGMVV 199
           E +A  +V+
Sbjct: 163 EEVARKLVI 171


>gi|124430752 kinesin family member 26B [Homo sapiens]
          Length = 2108

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 6/88 (6%)

Query: 121 LDRETEEILADVLKVEVFRQ--TVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQ 178
           L R+T E  +  LKV+  ++  T+ D +  G    F  +G  V PK    D        Q
Sbjct: 461 LARDTSES-SSFLKVDPRKKQITLYDPLTCGGQNAFQKRGNQVPPKMFAFDAVFPQDASQ 519

Query: 179 VPLVAGTVNRGSEVIAAGMVVNDWCAFC 206
             + AGTV   +EVI + +   D C FC
Sbjct: 520 AEVCAGTV---AEVIQSVVNGADGCVFC 544


>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
          Length = 248

 Score = 29.3 bits (64), Expect = 3.3
 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 98  EERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQ 157
           E R  A G+V   N  + LV  +LDR  E +   + K+E   +  AD+         S +
Sbjct: 40  ERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEE-AEKAADE---------SER 89

Query: 158 GGLVHPKTSIEDQDELS----SLLQVPLVAGTVNRGSEVIAAGMVV 199
           G  V    +++D++++      L +   +A   +R  E +A  +V+
Sbjct: 90  GMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVI 135


>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
          Length = 285

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 29/129 (22%), Positives = 57/129 (44%), Gaps = 16/129 (12%)

Query: 77  TDQELQHIRNSLPDTVQIRRVEERLSA--LGNVTTCNDYVALVHPDLDRETEEILADVLK 134
           T+ EL     +L D  +   + E+ +A     V + N  + LV  +LDR  E +   + K
Sbjct: 54  TEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQK 113

Query: 135 VEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELS----SLLQVPLVAGTVNRGS 190
           +E   +  AD+         S +G  V    +++D++++      L +   +A   +R  
Sbjct: 114 LEE-AEKAADE---------SERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163

Query: 191 EVIAAGMVV 199
           E +A  +V+
Sbjct: 164 EEVARKLVI 172


>gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens]
          Length = 566

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 15/61 (24%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 176 LLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATS 235
           L +  L++G ++R  ++ +  ++   W      D  S  ++VV+ +FK+     ST+ T 
Sbjct: 196 LTETSLISGNLHRIGDITSCSVL---WLNNAFQDVESENVNVVKRLFKIQNLNASTVRTV 252

Query: 236 M 236
           M
Sbjct: 253 M 253


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 8/68 (11%)

Query: 111  NDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQ 170
            ND+V  V  D D   EE        +  R+T A  V+    C F  +  +   ++ +EDQ
Sbjct: 1258 NDFVKTVLVDEDARPEE--------KELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQ 1309

Query: 171  DELSSLLQ 178
            + L +  Q
Sbjct: 1310 ESLQTCEQ 1317


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 15/63 (23%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 80   ELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFR 139
            E++   N   D +++  ++ ++S L N     +   +   D +R+ EEI+ D+  +E  R
Sbjct: 1537 EIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIM---DYNRDIEEIMKDIRNLEDIR 1593

Query: 140  QTV 142
            +T+
Sbjct: 1594 KTL 1596


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,133,708
Number of Sequences: 37866
Number of extensions: 318924
Number of successful extensions: 725
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 712
Number of HSP's gapped (non-prelim): 14
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.