Search of human proteins with 31542711

Search of human proteins with 31542711

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542711 ANT2-binding protein [Homo sapiens]
         (371 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542711 ANT2-binding protein [Homo sapiens]                       727   0.0  
gi|189027121 solute carrier family 35, member F1 [Homo sapiens]        45   8e-05
gi|6912668 solute carrier family 35 member 3A [Homo sapiens]           45   8e-05
gi|109948265 solute carrier family 35, member A2 isoform c [Homo...    42   7e-04
gi|5032211 solute carrier family 35, member A2 isoform a [Homo s...    42   7e-04
gi|164607128 solute carrier family 35, member E1 [Homo sapiens]        34   0.24 
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                    32   0.70 
gi|33598916 claudin 10 isoform a [Homo sapiens]                        32   0.92 
gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo ...    32   1.2  
gi|5921465 claudin 10 isoform b [Homo sapiens]                         32   1.2  
gi|5453621 solute carrier family 35 (CMP-sialic acid transporter...    32   1.2  
gi|55741571 leucine rich repeat and fibronectin type III domain ...    31   2.0  
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                        30   2.7  
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         30   2.7  
gi|32455271 protein-O-mannosyltransferase 2 [Homo sapiens]             29   7.8  
gi|110611919 UDP glucuronosyltransferase 2 family, polypeptide A...    29   7.8  
gi|157787091 UDP glucuronosyltransferase 2 family, polypeptide A...    29   7.8  
gi|21361476 unc-50 homolog [Homo sapiens]                              29   7.8  

>gi|31542711 ANT2-binding protein [Homo sapiens]
          Length = 371

 Score =  727 bits (1876), Expect = 0.0
 Identities = 371/371 (100%), Positives = 371/371 (100%)

Query: 1   MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFS 60
           MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFS
Sbjct: 1   MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFS 60

Query: 61  CLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQML 120
           CLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQML
Sbjct: 61  CLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQML 120

Query: 121 RGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGD 180
           RGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGD
Sbjct: 121 RGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGD 180

Query: 181 LLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGSFSG 240
           LLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGSFSG
Sbjct: 181 LLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGSFSG 240

Query: 241 NPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRT 300
           NPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRT
Sbjct: 241 NPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRT 300

Query: 301 VVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPLLGRLSRGRPLAEESEQERLL 360
           VVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPLLGRLSRGRPLAEESEQERLL
Sbjct: 301 VVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPLLGRLSRGRPLAEESEQERLL 360

Query: 361 GGTRTPINDAS 371
           GGTRTPINDAS
Sbjct: 361 GGTRTPINDAS 371


>gi|189027121 solute carrier family 35, member F1 [Homo sapiens]
          Length = 408

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 67/242 (27%), Positives = 105/242 (43%), Gaps = 27/242 (11%)

Query: 96  LCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGL 155
           L D+    L+  A   T+ +S Q+L   VI    L S  FL  R     ++GI+  I G+
Sbjct: 137 LIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGM 196

Query: 156 -VVVGLADLLSKHDSQHKLSEVITGDLLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGT 214
             +VG   L+ +H  Q      + GDLL++    +  I  V EE  +    +  +  +G 
Sbjct: 197 GCMVGADVLVGRH--QGAGENKLVGDLLVLGGATLYGISNVWEEYII--RTLSRVEFLGM 252

Query: 215 EGLFGFVILSLLLVPMYYIPAGSFSGNPRGTLEDALDAFCQVGQQPLIAVALLGNISSIA 274
            GLFG     + L  M +          +  L+   D   Q+G   L+ V    +     
Sbjct: 253 IGLFGAFFSGIQLAIMEH----------KELLKVPWD--WQIG---LLYVGF--SACMFG 295

Query: 275 FFNFAGISVTKELSATTRMVLDSLRTVVIWAL--SLALGWEAFHALQILGFLILLIGTAL 332
            ++F  + V K+ SAT+  V  SL T  +++L   L L    F  L +L F  +LIG  L
Sbjct: 296 LYSFMPV-VIKKTSATS--VNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVL 352

Query: 333 YN 334
           Y+
Sbjct: 353 YS 354


>gi|6912668 solute carrier family 35 member 3A [Homo sapiens]
          Length = 325

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 5/108 (4%)

Query: 84  QPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLS 143
           +P   L    P+       +L+YVAL+   A+++Q+     I+ T LFSV+ L ++L + 
Sbjct: 80  KPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGVY 139

Query: 144 QWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGDLLIIMAQIIVA 191
           QWL ++     +++ G+A +    DSQ    E+  G   + +  ++ A
Sbjct: 140 QWLSLV-----ILMTGVAFVQWPSDSQLDSKELSAGSQFVGLMAVLTA 182


>gi|109948265 solute carrier family 35, member A2 isoform c [Homo
           sapiens]
          Length = 393

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 23/65 (35%), Positives = 34/65 (52%)

Query: 94  PALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIA 153
           P+L      +L YVA++   A++FQ+     I+ T LFSV  L R L   QW  +L    
Sbjct: 118 PSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFT 177

Query: 154 GLVVV 158
           G+ +V
Sbjct: 178 GVAIV 182


>gi|5032211 solute carrier family 35, member A2 isoform a [Homo
           sapiens]
          Length = 396

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 23/65 (35%), Positives = 34/65 (52%)

Query: 94  PALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIA 153
           P+L      +L YVA++   A++FQ+     I+ T LFSV  L R L   QW  +L    
Sbjct: 118 PSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFT 177

Query: 154 GLVVV 158
           G+ +V
Sbjct: 178 GVAIV 182


>gi|164607128 solute carrier family 35, member E1 [Homo sapiens]
          Length = 410

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 47/255 (18%), Positives = 102/255 (40%), Gaps = 34/255 (13%)

Query: 86  FNPLLFLPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQW 145
           F P   LP A      +   +V++     S    ++  + I+  L S   +  +     +
Sbjct: 107 FYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQSTKVY 166

Query: 146 LGILATIAGLVVVGLADLLSKHDSQHKLSEVITGDLLIIMAQIIVAIQMVLEEKFVYKHN 205
           L ++  I+G+++  + +L          S  + G +  + A +  ++Q +  +K +    
Sbjct: 167 LSLIPIISGVLLATVTEL----------SFDMWGLVSALAATLCFSLQNIFSKKVLRDSR 216

Query: 206 VHPLRAVGTEGLFG--FVILSLLLVPMYYIPAGSFSGN----PRGTLEDALDAFCQVGQQ 259
           +H LR +   G     F+I + +LV +      S        P   L  A+  FC   Q 
Sbjct: 217 IHHLRLLNILGCHAVFFMIPTWVLVDLSAFLVSSDLTYVYQWPWTLLLLAVSGFCNFAQN 276

Query: 260 PLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRTVVIWALSLALGWEAFHALQ 319
            +IA ++L  +S +++                  V ++ + +++  +SL +      +  
Sbjct: 277 -VIAFSILNLVSPLSY-----------------SVANATKRIMVITVSLIMLRNPVTSTN 318

Query: 320 ILGFLILLIGTALYN 334
           +LG +  ++G  LYN
Sbjct: 319 VLGMMTAILGVFLYN 333



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 23/106 (21%), Positives = 41/106 (38%)

Query: 76  SDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAF 135
           SD +   Q P+  LL      C+     + +  LN+ S  S+ +      I     S+  
Sbjct: 250 SDLTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIM 309

Query: 136 LGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGDL 181
           L   +  +  LG++  I G+ +       +   ++  L  V T DL
Sbjct: 310 LRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARKHLLPVTTADL 355


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 15  LVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFSCLAAFYLLRCRAAG 74
           + T + + ++A W    +   C G  +       L    + LG F  + A + ++C   G
Sbjct: 30  VTTRASSVITATWVYQGLWMNCAGYIQACRG---LMIAAVSLGFFGSIFALFGMKCTKVG 86

Query: 75  QSDSSVDPQQPFNPLLFLPPALCDMTGTSL 104
            SD +         ++F+   LC MTG SL
Sbjct: 87  GSDKAKAKIACLAGIVFILSGLCSMTGCSL 116


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 16/106 (15%)

Query: 15  LVTGSINTLSAKWADNFMAEGCGGSKEHSFQ----------HPFLQA------VGMFLGE 58
           + T + + ++A W    +   C G+   SF             ++QA        + LG 
Sbjct: 30  VTTRASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVSLGF 89

Query: 59  FSCLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSL 104
           F  + A + ++C   G SD +         ++F+   LC MTG SL
Sbjct: 90  FGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSL 135


>gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo
           sapiens]
          Length = 1581

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 92  LPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILAT 151
           LP A+  +T    +  A +       Q  +GA  I+  L S AF GRRLVLS    ILA 
Sbjct: 253 LPIAMRALTNYQRLCEAFDAQVRKDIQGTQGARAIWQAL-SHAF-GRRLVLSSTFRILAD 310

Query: 152 IAG----LVVVGLADLLSKHD 168
           + G    L + G+ D L K +
Sbjct: 311 LLGFAGPLCIFGIVDHLGKEN 331



 Score = 28.9 bits (63), Expect = 7.8
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 14/119 (11%)

Query: 212 VGTEGLFGFVILSLLLVPMYYIPAGSFSGNPRGTLEDALDAFCQVGQQPLIAVALLGNIS 271
           +G   L G  ++ +LL P+ Y  A   S   R TLE + +   Q  +       +L  I 
Sbjct: 456 LGVSALIGAAVI-ILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNE-------MLRGIK 507

Query: 272 SIAFFNFAGISVTKELSATTRMVLDSLRTVVIW-ALSLALGWEAFHALQILGFLILLIG 329
            +  + +  I  T+ +  T R  + SLR   I+ ++S+ +      A+ I   LI  +G
Sbjct: 508 LLKLYAWENIFRTR-VETTRRKEMTSLRAFAIYTSISIFMN----TAIPIAAVLITFVG 561


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 17/56 (30%), Positives = 26/56 (46%)

Query: 49  LQAVGMFLGEFSCLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSL 104
           L    + LG F  + A + ++C   G SD +         ++F+   LC MTG SL
Sbjct: 82  LMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSL 137


>gi|5453621 solute carrier family 35 (CMP-sialic acid transporter),
           member A1 [Homo sapiens]
          Length = 337

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 18/65 (27%), Positives = 32/65 (49%)

Query: 94  PALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIA 153
           P+L      ++ ++AL+   A+ +Q+     I  T L +V  L R L   QW+ +    A
Sbjct: 94  PSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCA 153

Query: 154 GLVVV 158
           G+ +V
Sbjct: 154 GVTLV 158


>gi|55741571 leucine rich repeat and fibronectin type III domain
           containing 2 [Homo sapiens]
          Length = 789

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 141 VLSQWLGILATIAGLVVVGLADLLSKHD---SQHKLSEVITGDLLIIMAQIIVAIQMV 195
           VL+ W     T+    +VG A   +K D    Q   S+++ G +++++  IIVA  +V
Sbjct: 491 VLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLV 548


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 8/129 (6%)

Query: 49  LQAVGMFLGEFSCLAAFYLLRC-RAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTS---- 103
           L  VG+ LG    L + + L+C R     DS+       + ++F+   LC + G S    
Sbjct: 82  LMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFAN 141

Query: 104 LMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADL 163
           ++     M++A+ +  + G V      ++    G  L +    G L  I G+++      
Sbjct: 142 MLVTNFWMSTANMYTGMGGMVQTVQTRYT---FGAALFVGWVAGGLTLIGGVMMCIACRG 198

Query: 164 LSKHDSQHK 172
           L+  ++ +K
Sbjct: 199 LAPEETNYK 207


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 8/129 (6%)

Query: 49  LQAVGMFLGEFSCLAAFYLLRC-RAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTS---- 103
           L  VG+ LG    L + + L+C R     DS+       + ++F+   LC + G S    
Sbjct: 82  LMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFAN 141

Query: 104 LMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADL 163
           ++     M++A+ +  + G V      ++    G  L +    G L  I G+++      
Sbjct: 142 MLVTNFWMSTANMYTGMGGMVQTVQTRYT---FGAALFVGWVAGGLTLIGGVMMCIACRG 198

Query: 164 LSKHDSQHK 172
           L+  ++ +K
Sbjct: 199 LAPEETNYK 207


>gi|32455271 protein-O-mannosyltransferase 2 [Homo sapiens]
          Length = 750

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 3/53 (5%)

Query: 288 SATTRMVLDSLRTVVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPL 340
           S  T ++ D+L  +  W L+    W     + + G L LL+GTA    L  PL
Sbjct: 674 SMLTGILWDTLLRLCAWGLA---SWPLARGIHVAGILSLLLGTAYSFYLFHPL 723


>gi|110611919 UDP glucuronosyltransferase 2 family, polypeptide A1
           [Homo sapiens]
          Length = 527

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 9/24 (37%), Positives = 18/24 (75%)

Query: 310 LGWEAFHALQILGFLILLIGTALY 333
           L W  +H+L ++GFL++ + TA++
Sbjct: 481 LTWFQYHSLDVIGFLLVCVTTAIF 504


>gi|157787091 UDP glucuronosyltransferase 2 family, polypeptide A2
           [Homo sapiens]
          Length = 528

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 9/24 (37%), Positives = 18/24 (75%)

Query: 310 LGWEAFHALQILGFLILLIGTALY 333
           L W  +H+L ++GFL++ + TA++
Sbjct: 482 LTWFQYHSLDVIGFLLVCVTTAIF 505


>gi|21361476 unc-50 homolog [Homo sapiens]
          Length = 259

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 275 FFNFAGISVTKELSATTRMVLDSLRTVVIWALSLALGWEAFHAL 318
           +  F G S    L  T  ++      ++++ LSLALGW   H L
Sbjct: 207 YVTFLGYSALPFLKNTVILLYPFAPLILLYGLSLALGWNFTHTL 250


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,397,330
Number of Sequences: 37866
Number of extensions: 492932
Number of successful extensions: 1410
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1397
Number of HSP's gapped (non-prelim): 21
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.