Search of human proteins with 31455614

Search of human proteins with 31455614

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31455614 Der1-like domain family, member 2 [Homo sapiens]
         (239 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31455614 Der1-like domain family, member 2 [Homo sapiens]          494   e-140
gi|50845411 derlin 3 isoform 2 [Homo sapiens]                         379   e-105
gi|209364542 derlin 3 isoform 1 [Homo sapiens]                        345   2e-95
gi|50845409 derlin 3 isoform 3 [Homo sapiens]                         345   2e-95
gi|13236516 Der1-like domain family, member 1 isoform a [Homo sa...   145   2e-35
gi|197927278 Der1-like domain family, member 1 isoform b [Homo s...   120   8e-28
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      30   1.8  
gi|239756978 PREDICTED: hypothetical protein XP_002345135 [Homo ...    28   9.2  

>gi|31455614 Der1-like domain family, member 2 [Homo sapiens]
          Length = 239

 Score =  494 bits (1272), Expect = e-140
 Identities = 239/239 (100%), Positives = 239/239 (100%)

Query: 1   MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 60
           MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
Sbjct: 1   MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 60

Query: 61  FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 120
           FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
Sbjct: 61  FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 120

Query: 121 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 180
           GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
Sbjct: 121 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 180

Query: 181 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG 239
           IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
Sbjct: 181 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG 239


>gi|50845411 derlin 3 isoform 2 [Homo sapiens]
          Length = 235

 Score =  379 bits (973), Expect = e-105
 Identities = 177/227 (77%), Positives = 200/227 (88%)

Query: 1   MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 60
           MA+Q L  E+LQ+P V+RAYT ACVLTTAAVQLEL++PFQLYFNP L+F+ FQ+WRL+TN
Sbjct: 1   MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60

Query: 61  FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 120
           FLFFGP+GF+F FNM+F++RYCRMLEEGSFRGRTADFVFMFLFGG LMTL GL  SL FL
Sbjct: 61  FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120

Query: 121 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 180
           GQA   MLVYVWSRR+P VR+NFFGLL FQAPFLPW LMGFSLLLGNSI+VDLLGIAVGH
Sbjct: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180

Query: 181 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPG 227
           IY+FLEDVFPNQPGG R+L+TP  LK + D P EDPNY PLPEE+PG
Sbjct: 181 IYYFLEDVFPNQPGGKRLLQTPGFLKLLLDAPAEDPNYLPLPEEQPG 227


>gi|209364542 derlin 3 isoform 1 [Homo sapiens]
          Length = 239

 Score =  345 bits (886), Expect = 2e-95
 Identities = 162/205 (79%), Positives = 183/205 (89%)

Query: 1   MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 60
           MA+Q L  E+LQ+P V+RAYT ACVLTTAAVQLEL++PFQLYFNP L+F+ FQ+WRL+TN
Sbjct: 1   MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60

Query: 61  FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 120
           FLFFGP+GF+F FNM+F++RYCRMLEEGSFRGRTADFVFMFLFGG LMTL GL  SL FL
Sbjct: 61  FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120

Query: 121 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 180
           GQA   MLVYVWSRR+P VR+NFFGLL FQAPFLPW LMGFSLLLGNSI+VDLLGIAVGH
Sbjct: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180

Query: 181 IYFFLEDVFPNQPGGIRILKTPSIL 205
           IY+FLEDVFPNQPGG R+L+TP  L
Sbjct: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205


>gi|50845409 derlin 3 isoform 3 [Homo sapiens]
          Length = 205

 Score =  345 bits (886), Expect = 2e-95
 Identities = 162/205 (79%), Positives = 183/205 (89%)

Query: 1   MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 60
           MA+Q L  E+LQ+P V+RAYT ACVLTTAAVQLEL++PFQLYFNP L+F+ FQ+WRL+TN
Sbjct: 1   MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60

Query: 61  FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 120
           FLFFGP+GF+F FNM+F++RYCRMLEEGSFRGRTADFVFMFLFGG LMTL GL  SL FL
Sbjct: 61  FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120

Query: 121 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 180
           GQA   MLVYVWSRR+P VR+NFFGLL FQAPFLPW LMGFSLLLGNSI+VDLLGIAVGH
Sbjct: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180

Query: 181 IYFFLEDVFPNQPGGIRILKTPSIL 205
           IY+FLEDVFPNQPGG R+L+TP  L
Sbjct: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205


>gi|13236516 Der1-like domain family, member 1 isoform a [Homo
           sapiens]
          Length = 251

 Score =  145 bits (367), Expect = 2e-35
 Identities = 90/254 (35%), Positives = 130/254 (51%), Gaps = 37/254 (14%)

Query: 10  YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFF--GP- 66
           +  IP ++R +  A V      +L LI+P  L+  PE     FQIWR IT   +F  GP 
Sbjct: 8   FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67

Query: 67  VGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTI 126
            GF +L N+ FLY+Y   LE G+F GR AD++FM LF    + + GL + +  L     +
Sbjct: 68  TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127

Query: 127 MLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLE 186
            ++YVW++ N  + ++F+    F+A +LPWV++GF+ ++G S+I +L+G  VGH+YFFL 
Sbjct: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187

Query: 187 DVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPG--GFA-------------- 230
             +P   GG   L TP  L            Y  LP  R G  GF               
Sbjct: 188 FRYPMDLGGRNFLSTPQFL------------YRWLPSRRGGVSGFGVPPASMRRAADQNG 235

Query: 231 ------WGEGQRLG 238
                 WG+G RLG
Sbjct: 236 GGGRHNWGQGFRLG 249


>gi|197927278 Der1-like domain family, member 1 isoform b [Homo
           sapiens]
          Length = 231

 Score =  120 bits (302), Expect = 8e-28
 Identities = 77/233 (33%), Positives = 120/233 (51%), Gaps = 15/233 (6%)

Query: 10  YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFF--GP- 66
           +  IP ++R +  A V      +L LI+P  L+  PE     FQIWR IT   +F  GP 
Sbjct: 8   FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67

Query: 67  VGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTI 126
            GF +L N+ FLY+Y   LE G+F GR AD++FM LF    + + GL + +  L     +
Sbjct: 68  TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127

Query: 127 MLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLE 186
            ++YVW++ N  + ++F+    F+A +LPWV++GF+ ++G S  +DL G        FL 
Sbjct: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFLSTPQFLY 187

Query: 187 DVFPNQPGGIRILKT-PSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLG 238
              P++ GG+      P+ ++   D       +N           WG+G RLG
Sbjct: 188 RWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHN-----------WGQGFRLG 229


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 11/94 (11%)

Query: 55   WRLITNFL---FFGPVGFNFLFNMIFL-YRYCRMLEEGSF---RGRTADFVFMFLFGGF- 106
            W  + N+    F GPV F  L N+IFL    C+M++  +         + +  ++ G F 
Sbjct: 970  WLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFA 1029

Query: 107  LMTLFGLFVS--LVFLGQAFTIMLVYVWSRRNPY 138
            L+ L GL  S  L+F+ +  TI++ Y+++  N +
Sbjct: 1030 LLCLLGLTWSFGLLFINEE-TIVMAYLFTIFNAF 1062


>gi|239756978 PREDICTED: hypothetical protein XP_002345135 [Homo
           sapiens]
          Length = 187

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 15/43 (34%), Positives = 20/43 (46%), Gaps = 5/43 (11%)

Query: 188 VFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFA 230
           V PN+PG     + P +    +   +E P   P  EE PGG A
Sbjct: 57  VAPNRPG-----QRPRVAAGAWPRSEEGPEVWPRSEEGPGGLA 94


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.333    0.150    0.486 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,337,855
Number of Sequences: 37866
Number of extensions: 412141
Number of successful extensions: 992
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 984
Number of HSP's gapped (non-prelim): 8
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.