Guide to the Human Genome
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Search of human proteins with 31317259

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31317259 tafazzin isoform 2 [Homo sapiens]
         (262 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31317259 tafazzin isoform 2 [Homo sapiens]                         561   e-160
gi|4507371 tafazzin isoform 1 [Homo sapiens]                          545   e-155
gi|31317263 tafazzin isoform 4 [Homo sapiens]                         522   e-148
gi|31317261 tafazzin isoform 3 [Homo sapiens]                         506   e-144
gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo ...    31   1.3  
gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo...    31   1.3  
gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]          30   2.8  
gi|5454102 transforming, acidic coiled-coil containing protein 3...    29   3.6  
gi|5730102 transient receptor potential cation channel, subfamil...    28   6.2  
gi|239755565 PREDICTED: hypothetical protein [Homo sapiens]            28   6.2  
gi|239750071 PREDICTED: hypothetical protein XP_002347270 [Homo ...    28   6.2  
gi|239744380 PREDICTED: hypothetical protein XP_002343131 [Homo ...    28   6.2  
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo...    28   6.2  
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]     28   6.2  
gi|42794273 F-box and leucine-rich repeat protein 22 [Homo sapiens]    28   6.2  

>gi|31317259 tafazzin isoform 2 [Homo sapiens]
          Length = 262

 Score =  561 bits (1445), Expect = e-160
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIIL 180
           VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIIL
Sbjct: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIIL 180

Query: 181 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI 240
           PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI
Sbjct: 181 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI 240

Query: 241 QEEFQHLKTQAEQLHNHLQPGR 262
           QEEFQHLKTQAEQLHNHLQPGR
Sbjct: 241 QEEFQHLKTQAEQLHNHLQPGR 262


>gi|4507371 tafazzin isoform 1 [Homo sapiens]
          Length = 292

 Score =  545 bits (1404), Expect = e-155
 Identities = 262/292 (89%), Positives = 262/292 (89%), Gaps = 30/292 (10%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRG------------------------------DGVYQKGMDFILEKLNHGDWVHIFPE 150
           VCRG                              DGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180

Query: 151 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 210
           GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240

Query: 211 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 262
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292


>gi|31317263 tafazzin isoform 4 [Homo sapiens]
          Length = 248

 Score =  522 bits (1344), Expect = e-148
 Identities = 248/262 (94%), Positives = 248/262 (94%), Gaps = 14/262 (5%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIIL 180
           VCRGDGVYQKGMDFILEKLNHGDWVHIFPE              GIGRLIAECHLNPIIL
Sbjct: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPE--------------GIGRLIAECHLNPIIL 166

Query: 181 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI 240
           PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI
Sbjct: 167 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI 226

Query: 241 QEEFQHLKTQAEQLHNHLQPGR 262
           QEEFQHLKTQAEQLHNHLQPGR
Sbjct: 227 QEEFQHLKTQAEQLHNHLQPGR 248


>gi|31317261 tafazzin isoform 3 [Homo sapiens]
          Length = 278

 Score =  506 bits (1303), Expect = e-144
 Identities = 248/292 (84%), Positives = 248/292 (84%), Gaps = 44/292 (15%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCR------------------------------GDGVYQKGMDFILEKLNHGDWVHIFPE 150
           VCR                              GDGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180

Query: 151 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 210
                         GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 181 --------------GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 226

Query: 211 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 262
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 227 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 278


>gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 41/150 (27%), Positives = 64/150 (42%), Gaps = 17/150 (11%)

Query: 37  KYMNHLTVHNREVLYELIEKRG-----PATPLITVSNHQSCMDDPHLWGILKLRHIWNLK 91
           K +  + +H + +    +E RG     P+ P + VSNHQS +D   +  +L  R +   K
Sbjct: 67  KILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGRCVPIAK 126

Query: 92  L-MRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGD-WVHIFP 149
             + W  +A   C+   L    F   K      GD +    M  + + L   D  V +FP
Sbjct: 127 RELLWAGSAGLACW---LAGVIFIDRKRT----GDAI--SVMSEVAQTLLTQDVRVWVFP 177

Query: 150 EGKVNMSSEFLRFKWGIGRLIAECHLNPII 179
           EG  N +   L FK G   L  +  + PI+
Sbjct: 178 EGTRNHNGSMLPFKRGAFHLAVQAQV-PIV 206


>gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 41/150 (27%), Positives = 64/150 (42%), Gaps = 17/150 (11%)

Query: 37  KYMNHLTVHNREVLYELIEKRG-----PATPLITVSNHQSCMDDPHLWGILKLRHIWNLK 91
           K +  + +H + +    +E RG     P+ P + VSNHQS +D   +  +L  R +   K
Sbjct: 67  KILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGRCVPIAK 126

Query: 92  L-MRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGD-WVHIFP 149
             + W  +A   C+   L    F   K      GD +    M  + + L   D  V +FP
Sbjct: 127 RELLWAGSAGLACW---LAGVIFIDRKRT----GDAI--SVMSEVAQTLLTQDVRVWVFP 177

Query: 150 EGKVNMSSEFLRFKWGIGRLIAECHLNPII 179
           EG  N +   L FK G   L  +  + PI+
Sbjct: 178 EGTRNHNGSMLPFKRGAFHLAVQAQV-PIV 206


>gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]
          Length = 307

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 2/36 (5%)

Query: 3   LHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKY 38
           L +KW FP   P  W L  SV++  + T   FW  Y
Sbjct: 120 LWLKWRFPGWVP--WLLLGSVLISFIITLLFFWVNY 153


>gi|5454102 transforming, acidic coiled-coil containing protein 3
           [Homo sapiens]
          Length = 838

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 11/65 (16%)

Query: 191 LPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQ 250
           +P  PP  P  G       G P S  P+++ L+   K    + KA     QEE + L+++
Sbjct: 613 VPGPPPGVPAPG-------GPPLSTGPIVDLLQYSQKDLDAVVKAT----QEENRELRSR 661

Query: 251 AEQLH 255
            E+LH
Sbjct: 662 CEELH 666


>gi|5730102 transient receptor potential cation channel, subfamily
           C, member 6 [Homo sapiens]
          Length = 931

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIIL 180
           +CR     +  ++  +E L  GD       G+ N+S   L  K+ + + +A  +    +L
Sbjct: 335 LCRNTEEVEAILNGDVETLQSGD------HGRPNLSRLKLAIKYEVKKFVAHPNCQQQLL 388

Query: 181 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSAL 216
            +W+  ++ +   +     +F   + V IG PF AL
Sbjct: 389 SIWYENLSGLRQQTMAV--KFLVVLAVAIGLPFLAL 422


>gi|239755565 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 68  NHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGV 127
           ++Q+ +   +L G L LRH ++   M  T   + + + K   S  F   +    C G  V
Sbjct: 4   DNQTVISKDYLQGGLLLRHDYD-HFMNATSGISPLAWRKMKVSRGFCQAQAGAYCLGAYV 62

Query: 128 YQKGMDFIL 136
           Y +G+D +L
Sbjct: 63  YHEGIDVVL 71


>gi|239750071 PREDICTED: hypothetical protein XP_002347270 [Homo
           sapiens]
          Length = 257

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 68  NHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGV 127
           ++Q+ +   +L G L LRH ++   M  T   + + + K   S  F   +    C G  V
Sbjct: 4   DNQTVISKDYLQGGLLLRHDYD-HFMNATSGISPLAWRKMKVSRGFCQAQAGAYCLGAYV 62

Query: 128 YQKGMDFIL 136
           Y +G+D +L
Sbjct: 63  YHEGIDVVL 71


>gi|239744380 PREDICTED: hypothetical protein XP_002343131 [Homo
           sapiens]
          Length = 257

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 68  NHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGV 127
           ++Q+ +   +L G L LRH ++   M  T   + + + K   S  F   +    C G  V
Sbjct: 4   DNQTVISKDYLQGGLLLRHDYD-HFMNATSGISPLAWRKMKVSRGFCQAQAGAYCLGAYV 62

Query: 128 YQKGMDFIL 136
           Y +G+D +L
Sbjct: 63  YHEGIDVVL 71


>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
           sapiens]
          Length = 1044

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 4/38 (10%)

Query: 126 GVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFK 163
           G+ ++ + FIL      D+VH+  +GK N S +F RF+
Sbjct: 924 GINRERVPFILTY----DFVHVIQQGKTNNSEKFERFR 957


>gi|13376146 zinc finger and BTB domain containing 3 [Homo
          sapiens]
          Length = 574

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 10/62 (16%)

Query: 6  KWPFPAVPPLTWTLASSVVMGLVGTY------SCFWTKYMNHLTV----HNREVLYELIE 55
          KW   A P   W    S++ G VG Y        FW  + +  T+    H++++L  L E
Sbjct: 7  KWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQLLQSLRE 66

Query: 56 KR 57
          +R
Sbjct: 67 QR 68


>gi|42794273 F-box and leucine-rich repeat protein 22 [Homo
          sapiens]
          Length = 241

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 41 HLTVHNREVLYEL---IEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLK 91
          H+T  NRE L  L   ++K    +   T S      +DP LW +L  R +  L+
Sbjct: 2  HITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQ 55


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,402,260
Number of Sequences: 37866
Number of extensions: 508635
Number of successful extensions: 1609
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1598
Number of HSP's gapped (non-prelim): 19
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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