Guide to the Human Genome
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Search of human proteins with 30039706

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30039706 nicotinamide mononucleotide adenylyltransferase 3
[Homo sapiens]
         (215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30039706 nicotinamide mononucleotide adenylyltransferase 3 [H...   444   e-125
gi|20070321 nicotinamide mononucleotide adenylyltransferase 1 [H...   201   5e-52
gi|25141325 nicotinamide mononucleotide adenylyltransferase 2 is...    89   2e-18
gi|24307989 nicotinamide mononucleotide adenylyltransferase 2 is...    89   2e-18
gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]           32   0.41 
gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]            32   0.41 
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    30   2.0  
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ...    29   3.5  
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...    29   3.5  
gi|156119615 myosin IXA [Homo sapiens]                                 28   4.5  
gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho...    28   4.5  
gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho...    28   4.5  
gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho...    28   4.5  

>gi|30039706 nicotinamide mononucleotide adenylyltransferase 3 [Homo
           sapiens]
          Length = 215

 Score =  444 bits (1142), Expect = e-125
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVL 60
           MYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVL
Sbjct: 1   MYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVL 60

Query: 61  RHHHSKLLRSPPQMEGPDHGKALFSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIV 120
           RHHHSKLLRSPPQMEGPDHGKALFSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIV
Sbjct: 61  RHHHSKLLRSPPQMEGPDHGKALFSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIV 120

Query: 121 EKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKY 180
           EKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKY
Sbjct: 121 EKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKY 180

Query: 181 LIPDAVITYIKDHGLYTKGSTWKGKSTQSTEGKTS 215
           LIPDAVITYIKDHGLYTKGSTWKGKSTQSTEGKTS
Sbjct: 181 LIPDAVITYIKDHGLYTKGSTWKGKSTQSTEGKTS 215


>gi|20070321 nicotinamide mononucleotide adenylyltransferase 1 [Homo
           sapiens]
          Length = 279

 Score =  201 bits (510), Expect = 5e-52
 Identities = 104/218 (47%), Positives = 137/218 (62%), Gaps = 19/218 (8%)

Query: 2   YQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLR 61
           Y V++GIISPV D Y KK L  ++HRV MA LA + S W+ VD WES Q +W ET+KVLR
Sbjct: 41  YTVVKGIISPVGDAYKKKGLIPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLR 100

Query: 62  HHHSKLLRSP-------PQMEGP------------DHGKALFSTPAAVPELKLLCGADVL 102
           HH  KL  S        P +E P               K+L     AVP++KLLCGAD+L
Sbjct: 101 HHQEKLEASDCDHQQNSPTLERPGRKRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLL 160

Query: 103 KTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNE 162
           ++F  PNLWK   I +IV  +GL+CV R G+D + +I ES +L  H+ NIH+  E + N+
Sbjct: 161 ESFAVPNLWKSEDITQIVANYGLICVTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIAND 220

Query: 163 ISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGS 200
           IS+T IRRAL +GQS++YL+PD V  YI+ H LY+  S
Sbjct: 221 ISSTKIRRALRRGQSIRYLVPDLVQEYIEKHNLYSSES 258


>gi|25141325 nicotinamide mononucleotide adenylyltransferase 2
           isoform 2 [Homo sapiens]
          Length = 302

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 81/265 (30%), Positives = 110/265 (41%), Gaps = 69/265 (26%)

Query: 4   VIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHH 63
           VI GI+SPV+D+YGK+ L +S HR+ M +LA+Q SDWIRVDPWE  Q  W  T  VL HH
Sbjct: 38  VIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHH 97

Query: 64  HSKLLR------------------SPPQMEGPD---HGKALFSTPAAVPEL--------K 94
              + R                    PQ E P        + + P A   L        +
Sbjct: 98  RDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSR 157

Query: 95  LLCGADVLKTF----QTPNLWKDAHIQEI------------VEKF--------------- 123
           + C    ++ F    +  NL      +EI            +E F               
Sbjct: 158 ICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIV 217

Query: 124 ---GLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNE---ISATYIRRAL--GQG 175
              G+V V R   D    +  S ILR +++NI + K+ + +    +S+T  R AL  G G
Sbjct: 218 GDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDG 277

Query: 176 QSVKYLIPDAVITYIKDHGLYTKGS 200
             V YL    VI YI    LY   S
Sbjct: 278 HVVDYL-SQPVIDYILKSQLYINAS 301


>gi|24307989 nicotinamide mononucleotide adenylyltransferase 2
           isoform 1 [Homo sapiens]
          Length = 307

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 81/265 (30%), Positives = 110/265 (41%), Gaps = 69/265 (26%)

Query: 4   VIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHH 63
           VI GI+SPV+D+YGK+ L +S HR+ M +LA+Q SDWIRVDPWE  Q  W  T  VL HH
Sbjct: 43  VIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHH 102

Query: 64  HSKLLR------------------SPPQMEGPD---HGKALFSTPAAVPEL--------K 94
              + R                    PQ E P        + + P A   L        +
Sbjct: 103 RDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSR 162

Query: 95  LLCGADVLKTF----QTPNLWKDAHIQEI------------VEKF--------------- 123
           + C    ++ F    +  NL      +EI            +E F               
Sbjct: 163 ICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIV 222

Query: 124 ---GLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNE---ISATYIRRAL--GQG 175
              G+V V R   D    +  S ILR +++NI + K+ + +    +S+T  R AL  G G
Sbjct: 223 GDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDG 282

Query: 176 QSVKYLIPDAVITYIKDHGLYTKGS 200
             V YL    VI YI    LY   S
Sbjct: 283 HVVDYL-SQPVIDYILKSQLYINAS 306


>gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]
          Length = 649

 Score = 32.0 bits (71), Expect = 0.41
 Identities = 20/71 (28%), Positives = 35/71 (49%)

Query: 34  ALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKALFSTPAAVPEL 93
           ++Q++   +   W+S Q Q +  V +    HS   R PP + G    KA  S P+++ + 
Sbjct: 322 SIQSARAAQAPHWKSLQQQDVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQ 381

Query: 94  KLLCGADVLKT 104
             LC A  ++T
Sbjct: 382 PCLCPAPSVRT 392


>gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]
          Length = 669

 Score = 32.0 bits (71), Expect = 0.41
 Identities = 20/71 (28%), Positives = 35/71 (49%)

Query: 34  ALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKALFSTPAAVPEL 93
           ++Q++   +   W+S Q Q +  V +    HS   R PP + G    KA  S P+++ + 
Sbjct: 342 SIQSARAAQAPHWKSLQQQDVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQ 401

Query: 94  KLLCGADVLKT 104
             LC A  ++T
Sbjct: 402 PCLCPAPSVRT 412


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 96   LCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLA 155
            L G+ +   FQ+  L     +Q +   FGL  VG  G   KG   ES  L  +Q  I  A
Sbjct: 1659 LAGSRLSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTG--GKG---ESGRLHHYQDGIRAA 1713

Query: 156  KEPVQNEI 163
            K  +Q EI
Sbjct: 1714 KRNIQIEI 1721


>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
           [Homo sapiens]
          Length = 1075

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 12/34 (35%), Positives = 19/34 (55%)

Query: 50  QAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKAL 83
           QA   E +K +  HH  +  SP ++EGP + K +
Sbjct: 652 QAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCM 685


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 12/34 (35%), Positives = 19/34 (55%)

Query: 50  QAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKAL 83
           QA   E +K +  HH  +  SP ++EGP + K +
Sbjct: 676 QAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCM 709


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 13/27 (48%), Positives = 18/27 (66%)

Query: 181  LIPDAVITYIKDHGLYTKGSTWKGKST 207
            L+ + +I YI+ HGLYT+G   K  ST
Sbjct: 2077 LVVEKLINYIEMHGLYTEGIYRKSGST 2103


>gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo
            sapiens]
          Length = 1645

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 19/78 (24%), Positives = 28/78 (35%), Gaps = 6/78 (7%)

Query: 72   PQMEGPDHGKALFSTPAAVP------ELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGL 125
            P    P HG  + S P + P      +  ++      +    PN   D H    V    L
Sbjct: 1502 PAPSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSL 1561

Query: 126  VCVGRVGHDPKGYIAESP 143
            V  G VG+   G+   +P
Sbjct: 1562 VNSGAVGNSEPGFRGLTP 1579


>gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo
            sapiens]
          Length = 1644

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 19/78 (24%), Positives = 28/78 (35%), Gaps = 6/78 (7%)

Query: 72   PQMEGPDHGKALFSTPAAVP------ELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGL 125
            P    P HG  + S P + P      +  ++      +    PN   D H    V    L
Sbjct: 1501 PAPSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSL 1560

Query: 126  VCVGRVGHDPKGYIAESP 143
            V  G VG+   G+   +P
Sbjct: 1561 VNSGAVGNSEPGFRGLTP 1578


>gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo
            sapiens]
          Length = 1640

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 19/78 (24%), Positives = 28/78 (35%), Gaps = 6/78 (7%)

Query: 72   PQMEGPDHGKALFSTPAAVP------ELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGL 125
            P    P HG  + S P + P      +  ++      +    PN   D H    V    L
Sbjct: 1497 PAPSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSL 1556

Query: 126  VCVGRVGHDPKGYIAESP 143
            V  G VG+   G+   +P
Sbjct: 1557 VNSGAVGNSEPGFRGLTP 1574


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,669,817
Number of Sequences: 37866
Number of extensions: 374413
Number of successful extensions: 776
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 764
Number of HSP's gapped (non-prelim): 15
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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