Guide to the Human Genome
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Search of human proteins with 122937275

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937275 alpha 1,3-galactosyltransferase 2 [Homo sapiens]
         (340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937275 alpha 1,3-galactosyltransferase 2 [Homo sapiens]         721   0.0  
gi|58331216 ABO blood group (alpha 1-3-N-acetylgalactosaminyltra...   229   2e-60
gi|32484985 globoside alpha-1,3-N-acetylgalactosaminyltransferas...   212   3e-55
gi|134288859 glycosyltransferase 6 domain containing 1 [Homo sap...   169   4e-42
gi|110624774 mannose receptor, C type 2 [Homo sapiens]                 29   5.3  
gi|21361771 phosphatidylinositol glycan class V [Homo sapiens]         29   5.3  
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]           29   6.9  
gi|24431977 XK, Kell blood group complex subunit-related family,...    29   6.9  
gi|134288915 myosin IIIB isoform 1 [Homo sapiens]                      28   9.0  
gi|134288892 myosin IIIB isoform 2 [Homo sapiens]                      28   9.0  
gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]     28   9.0  

>gi|122937275 alpha 1,3-galactosyltransferase 2 [Homo sapiens]
          Length = 340

 Score =  721 bits (1860), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MALKEGLRAWKRIFWRQILLTLGLLGLFLYGLPKFRHLEALIPMGVCPSATMSQLRDNFT 60
           MALKEGLRAWKRIFWRQILLTLGLLGLFLYGLPKFRHLEALIPMGVCPSATMSQLRDNFT
Sbjct: 1   MALKEGLRAWKRIFWRQILLTLGLLGLFLYGLPKFRHLEALIPMGVCPSATMSQLRDNFT 60

Query: 61  GALRPWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYLEKYLER 120
           GALRPWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYLEKYLER
Sbjct: 61  GALRPWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYLEKYLER 120

Query: 121 FLETAEQHFMAGQSVMYYVFTELPGAVPRVALGPGRRLPVERVARERRWQDVSMARMRTL 180
           FLETAEQHFMAGQSVMYYVFTELPGAVPRVALGPGRRLPVERVARERRWQDVSMARMRTL
Sbjct: 121 FLETAEQHFMAGQSVMYYVFTELPGAVPRVALGPGRRLPVERVARERRWQDVSMARMRTL 180

Query: 181 HAALGGLPGREAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHS 240
           HAALGGLPGREAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHS
Sbjct: 181 HAALGGLPGREAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHS 240

Query: 241 AAAMAWGQGDFYNHAAVFGGSVAALRGLTAHCAGGLDWDRARGLEARWHDESHLNKFFWL 300
           AAAMAWGQGDFYNHAAVFGGSVAALRGLTAHCAGGLDWDRARGLEARWHDESHLNKFFWL
Sbjct: 241 AAAMAWGQGDFYNHAAVFGGSVAALRGLTAHCAGGLDWDRARGLEARWHDESHLNKFFWL 300

Query: 301 HKPAKVLSPEFCWSPDIGPRAEIRRPRLLWAPKGYRLLRN 340
           HKPAKVLSPEFCWSPDIGPRAEIRRPRLLWAPKGYRLLRN
Sbjct: 301 HKPAKVLSPEFCWSPDIGPRAEIRRPRLLWAPKGYRLLRN 340


>gi|58331216 ABO blood group (alpha
           1-3-N-acetylgalactosaminyltransferase, alpha
           1-3-galactosyltransferase) [Homo sapiens]
          Length = 354

 Score =  229 bits (585), Expect = 2e-60
 Identities = 123/274 (44%), Positives = 161/274 (58%), Gaps = 2/274 (0%)

Query: 68  RPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYLEKYLERFLETAEQ 127
           R +VL  TPW API+W+G+F+ D+  ++ R QN TIGLT+FA+ +Y+  +L+ FLETAE+
Sbjct: 81  RKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVA-FLKLFLETAEK 139

Query: 128 HFMAGQSVMYYVFTELPGAVPRVALGPGRRLPVERVARERRWQDVSMARMRTLHAALGGL 187
           HFM G  V YYVFT+ P AVPRV LG GR+L V  V   +RWQDVSM RM  +       
Sbjct: 140 HFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERR 199

Query: 188 PGREAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHSAAAMAWG 247
              E  ++ C+DVD  F    G E L      LH   Y        +ER   S A +   
Sbjct: 200 FLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKD 259

Query: 248 QGDFYNHAAVFGGSVAALRGLTAHCAGGLDWDRARGLEARWHDESHLNKFFWLHKPAKVL 307
           +GDFY     FGGSV  ++ LT  C   +  D+A G+EA WHDESHLNK+   HKP KVL
Sbjct: 260 EGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVL 319

Query: 308 SPEFCWSPD-IGPRAEIRRPRLLWAPKGYRLLRN 340
           SPE+ W    +G  A +R+ R    PK ++ +RN
Sbjct: 320 SPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRN 353


>gi|32484985 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
           [Homo sapiens]
          Length = 347

 Score =  212 bits (540), Expect = 3e-55
 Identities = 107/244 (43%), Positives = 151/244 (61%), Gaps = 1/244 (0%)

Query: 70  EVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYLEKYLERFLETAEQHF 129
           ++LT TPW API+ +G+F+P++ +   +  NLTIG+T+FAVG+Y   +++ FLE+AE+ F
Sbjct: 78  QLLTLTPWLAPIVSEGTFNPELLQHIYQPLNLTIGVTVFAVGKYTH-FIQSFLESAEEFF 136

Query: 130 MAGQSVMYYVFTELPGAVPRVALGPGRRLPVERVARERRWQDVSMARMRTLHAALGGLPG 189
           M G  V YY+FT+ P AVP V LGP R L    +     W++ SM RM T+   +     
Sbjct: 137 MRGYRVHYYIFTDNPAAVPGVPLGPHRLLSSIPIQGHSHWEETSMRRMETISQHIAKRAH 196

Query: 190 REAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHSAAAMAWGQG 249
           RE  ++FC+DVD  F   +GPE L + VA +H  +Y  P    P+ER   S A +A  +G
Sbjct: 197 REVDYLFCLDVDMVFRNPWGPETLGDLVAAIHPSYYAVPRQQFPYERRRVSTAFVADSEG 256

Query: 250 DFYNHAAVFGGSVAALRGLTAHCAGGLDWDRARGLEARWHDESHLNKFFWLHKPAKVLSP 309
           DFY   AVFGG VA +   T  C   +  D+A G+ A W +ESHLN+ F  +KP+KVLSP
Sbjct: 257 DFYYGGAVFGGQVARVYEFTRGCHMAILADKANGIMAAWREESHLNRHFISNKPSKVLSP 316

Query: 310 EFCW 313
           E+ W
Sbjct: 317 EYLW 320


>gi|134288859 glycosyltransferase 6 domain containing 1 [Homo
           sapiens]
          Length = 276

 Score =  169 bits (427), Expect = 4e-42
 Identities = 88/239 (36%), Positives = 133/239 (55%), Gaps = 2/239 (0%)

Query: 65  PWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYLEKYLERFLET 124
           P  RP+V+T T W AP++W+G+FD  V ++  R++N+T+GL +FA GR+ E+YL  FL +
Sbjct: 39  PRKRPDVITKTDWLAPVLWEGTFDRRVLEKHYRRRNITVGLAVFATGRFAEEYLRPFLHS 98

Query: 125 AEQHFMAGQSVMYYVFTELPGAVPRVALGPGRRLPVERVARERRWQDVSMARMRTLHAAL 184
           A +HFM G  V++Y+  +    +P +   P R     +V  ER W D  +  +++L   +
Sbjct: 99  ANKHFMTGYRVIFYIMVDAFFKLPDIEPSPLRTFKAFKVGTERWWLDGPLVHVKSLGEHI 158

Query: 185 GGLPGREAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHSAAAM 244
                 E  F+F M  +Q F   FG E L   VAQLH+W Y   +   P+ER   SAA +
Sbjct: 159 ASHIQDEVDFLFSMAANQVFQNEFGVETLGPLVAQLHAWWYFRNTKNFPYERRPTSAACI 218

Query: 245 AWGQGDFYNHAAVFGGSVAALRGLTAHCAGGLDWDRARGLEARWHDESHLNKFFWLHKP 303
            +GQGDFY    + GG+   +         G+  D   GL + +  E HLNK+F+L+KP
Sbjct: 219 PFGQGDFYYGNLMVGGTPHNILDFIKEYLNGVIHDIKNGLNSTY--EKHLNKYFYLNKP 275


>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
          Length = 1479

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 22/117 (18%)

Query: 201 DQHFSGTFGPEALAESVAQLHSWHYHWPSWLLPFERDAHSAAAMAWGQG----------- 249
           ++HF      +   ES  ++H  H+    W+    RD     +  W  G           
Sbjct: 719 EEHFVANMLNKIFGESEPEIHEQHWF---WIGLNRRDPRGGQSWRWSDGVGFSYHNFDRS 775

Query: 250 ----DFYNHAAVFGGSVAALRGLTAHCAGGLDW--DRARGLEARWHDESHLNKFFWL 300
               D     AV    +A+L+ +   C   LDW     RG + R  D+S   +  WL
Sbjct: 776 RHDDDDIRGCAVL--DLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWL 830


>gi|21361771 phosphatidylinositol glycan class V [Homo sapiens]
          Length = 493

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 1/48 (2%)

Query: 19 LLTLGLLGLFLYGLPKFRHLEALIPMGVCPSATMSQLRDNFTGALRPW 66
          +LTL L  LF   +P   H EA  P  + PS  + QL +   G L  W
Sbjct: 20 ILTLMLQALFNAIIPD-HHAEAFSPPRLAPSGFVDQLVEGLLGGLSHW 66


>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
          Length = 490

 Score = 28.9 bits (63), Expect = 6.9
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 1/50 (2%)

Query: 65  PWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQNLTIGLTIFAVGRYL 114
           P + PE +    WGAPI W+ + DP  + ++  Q ++ + + I     YL
Sbjct: 210 PESLPEKMRPASWGAPISWEQA-DPFASLKKVGQDSIVLLICITVFLSYL 258


>gi|24431977 XK, Kell blood group complex subunit-related family,
           member 8 [Homo sapiens]
          Length = 395

 Score = 28.9 bits (63), Expect = 6.9
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 10/44 (22%)

Query: 297 FFWLHKPAKVLSPEFCWSPDIGPRAEIRRPRLLWAPKGYRLLRN 340
           + WLH       P  CW PD     ++   R L +P+GY+L +N
Sbjct: 338 YHWLH-------PSCCWKPD---PDQVDGARSLLSPEGYQLPQN 371


>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
          Length = 1314

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 41  LIPMGVCPSATMSQLRDNFTGALRPWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQN 100
           L+  GV    T ++LR N +     W  PEV+ C        +D S+D       AR   
Sbjct: 172 LVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQ-----YDSSYD-------ARCDV 219

Query: 101 LTIGLTIFAVG 111
            ++G+T   +G
Sbjct: 220 WSLGITAIELG 230


>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
          Length = 1341

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 41  LIPMGVCPSATMSQLRDNFTGALRPWARPEVLTCTPWGAPIIWDGSFDPDVAKQEARQQN 100
           L+  GV    T ++LR N +     W  PEV+ C        +D S+D       AR   
Sbjct: 172 LVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQ-----YDSSYD-------ARCDV 219

Query: 101 LTIGLTIFAVG 111
            ++G+T   +G
Sbjct: 220 WSLGITAIELG 230


>gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]
          Length = 372

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 4/80 (5%)

Query: 171 DVSMARMRTLHAALGGLPGREAHFMFCMDVDQHFSGTFGPEALAESVAQLHSWHYHWP-- 228
           D+S  + + L+       G  AH    M    +  G   P    +++ Q H+   HW   
Sbjct: 224 DISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLL 283

Query: 229 --SWLLPFERDAHSAAAMAW 246
               LLP  R  HS   + W
Sbjct: 284 KFDTLLPPGRLDHSMCIIPW 303


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.475 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,902,581
Number of Sequences: 37866
Number of extensions: 637462
Number of successful extensions: 1712
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1704
Number of HSP's gapped (non-prelim): 11
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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