BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29171311 G protein-coupled receptor 109A [Homo sapiens] (363 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29171311 G protein-coupled receptor 109A [Homo sapiens] 752 0.0 gi|157738694 G protein-coupled receptor 109B [Homo sapiens] 714 0.0 gi|14211851 G protein-coupled receptor 81 [Homo sapiens] 342 4e-94 gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens] 214 7e-56 gi|153792268 G protein-coupled receptor 31 [Homo sapiens] 189 4e-48 gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 154 2e-37 gi|33695097 G protein-coupled receptor 35 [Homo sapiens] 142 5e-34 gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 140 2e-33 gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 134 2e-31 gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 134 2e-31 gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 134 2e-31 gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 134 2e-31 gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 134 2e-31 gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 132 6e-31 gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 132 6e-31 gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 132 6e-31 gi|4557359 bradykinin receptor B2 [Homo sapiens] 131 8e-31 gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 127 2e-29 gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 126 3e-29 gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 126 3e-29 gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 126 3e-29 gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 125 8e-29 gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 124 1e-28 gi|47271392 succinate receptor 1 [Homo sapiens] 123 2e-28 gi|4506241 platelet-activating factor receptor [Homo sapiens] 123 2e-28 gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] 122 4e-28 gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] 122 4e-28 gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] 122 4e-28 gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] 122 4e-28 gi|149944554 somatostatin receptor 4 [Homo sapiens] 122 7e-28 >gi|29171311 G protein-coupled receptor 109A [Homo sapiens] Length = 363 Score = 752 bits (1942), Expect = 0.0 Identities = 363/363 (100%), Positives = 363/363 (100%) Query: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60 MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK Sbjct: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60 Query: 61 SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV 120 SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV Sbjct: 61 SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV 120 Query: 121 VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF 180 VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF Sbjct: 121 VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF 180 Query: 181 SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240 SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF Sbjct: 181 SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240 Query: 241 VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300 VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS Sbjct: 241 VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300 Query: 301 FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP 360 FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP Sbjct: 301 FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP 360 Query: 361 TSP 363 TSP Sbjct: 361 TSP 363 >gi|157738694 G protein-coupled receptor 109B [Homo sapiens] Length = 387 Score = 714 bits (1842), Expect = 0.0 Identities = 345/362 (95%), Positives = 353/362 (97%) Query: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60 MNRHHLQDHFLEIDKKNCCVFRDDFI KVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK Sbjct: 1 MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK 60 Query: 61 SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV 120 SSRIFLFNLAVADFLLIICLPF+MD YVRR DWKFGDIPCRL+LFM AMNRQGSIIFLTV Sbjct: 61 SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV 120 Query: 121 VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF 180 VAVDRYFRVVHPHHALNKISN TAAIISCLLWGIT+GLTVHLLKKK+ IQNG AN+C SF Sbjct: 121 VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISF 180 Query: 181 SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240 SICHTF+WHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF Sbjct: 181 SICHTFRWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF 240 Query: 241 VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300 VICFLPSVVVRI IFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS Sbjct: 241 VICFLPSVVVRIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS 300 Query: 301 FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP 360 FPNFFSTLINRCLQRK+TGEPDNNRSTSVELTGDPNKTRGAPEAL+ANSGEPWSPSYLGP Sbjct: 301 FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALIANSGEPWSPSYLGP 360 Query: 361 TS 362 TS Sbjct: 361 TS 362 >gi|14211851 G protein-coupled receptor 81 [Homo sapiens] Length = 346 Score = 342 bits (876), Expect = 4e-94 Identities = 180/341 (52%), Positives = 227/341 (66%), Gaps = 7/341 (2%) Query: 17 NCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLL 76 +CC D I +V+PP+L + F+ G LGNG+AL FCFH+K+WK S ++LFNLAVADFLL Sbjct: 5 SCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLL 64 Query: 77 IICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHAL 136 +ICLPF D Y+RR W FGDIPCR+ LF LAMNR GSI+FLTVVA DRYF+VVHPHHA+ Sbjct: 65 MICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAV 124 Query: 137 NKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLE 196 N IS R AA I C LW + I TV+LL + A C SF + WH+ MF LE Sbjct: 125 NTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLE 184 Query: 197 FFLPLGIILFCSARIIWSLRQR-QMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIF 255 FF+PLGIILFCS +I+WSLR+R Q+ R A++K+A FIMVVAIVF+ C+LPSV R+ Sbjct: 185 FFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFL 244 Query: 256 WLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQR 315 W + +S C+ SV A ITLSFTYMNSMLDP+VYYFSSPSFP F++ L L+ Sbjct: 245 WTVPSSA---CD--PSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKP 299 Query: 316 KMTGEPDNNRSTSVELTGDPNKT-RGAPEALMANSGEPWSP 355 K G R + ++ ++ + + S W P Sbjct: 300 KQPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDP 340 >gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens] Length = 423 Score = 214 bits (546), Expect = 7e-56 Identities = 118/282 (41%), Positives = 170/282 (60%), Gaps = 24/282 (8%) Query: 30 LPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVR 89 L P+L LEF+ GL+GN LAL+IFC H + W S+ +FL +L ADFLLI LP +D Y+ Sbjct: 95 LAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLL 154 Query: 90 RWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISC 149 W+FG C++ LFML+ NR S++FLT +A++RY +VV PHH L++ S AA ++ Sbjct: 155 HETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAG 214 Query: 150 LLWGITIGLTVHLLKKKMPIQNGGANLCSSFSI----CHTFQWHEAMFLLEFFLPLGIIL 205 LW + L HLL + C S+ + + +WH+A++LLEFFLPL +IL Sbjct: 215 GLWVGILLLNGHLL-----LSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALIL 269 Query: 206 FCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVV---VRIRIFWLLHTSG 262 F I ++R R + A +RA+ + +V V+ ICFLPS++ + FWL Sbjct: 270 FAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWL----- 324 Query: 263 TQNCEVYRSVDLA---FFITLSFTYMNSMLDPVVYYFSSPSF 301 RS+DL F +L+FTY+NS+LDPV+Y FSSP+F Sbjct: 325 ----SACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNF 362 >gi|153792268 G protein-coupled receptor 31 [Homo sapiens] Length = 319 Score = 189 bits (479), Expect = 4e-48 Identities = 110/296 (37%), Positives = 166/296 (56%), Gaps = 13/296 (4%) Query: 33 VLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWD 92 +LGLE GLLGN +ALW F F ++ WK ++L NLA+AD LL CLPFL Y+ Sbjct: 20 LLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQA 79 Query: 93 WKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLW 152 W G + C + F+L ++R + FL VA+DRY RVVHP +N +S + A +S L+W Sbjct: 80 WHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVW 139 Query: 153 GITIGLTVHLLKKKMPIQNGGANLCSSF----SICHTFQWHEAMFLLEFFLPLGIILFCS 208 + + LT L QN + C SF + W EA+ L+F LP G+I+FC+ Sbjct: 140 LLMVALTCPGLLISEAAQN--STRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCN 197 Query: 209 ARIIWSL--RQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHT-SGTQN 265 A II +L R R+ ++ K++RA + +V ++F +CFLP + R+ L+H + Sbjct: 198 AGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARV----LMHIFQNLGS 253 Query: 266 CEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEP 321 C +V +T S TY++S+L+PVVY FSSP+F + + + + + EP Sbjct: 254 CRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEP 309 >gi|4505557 purinergic receptor P2Y1 [Homo sapiens] Length = 373 Score = 154 bits (388), Expect = 2e-37 Identities = 93/321 (28%), Positives = 160/321 (49%), Gaps = 10/321 (3%) Query: 18 CCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLI 77 C + + F LP V L FI G LGN +A+W+F FH+K W +++FNLA+ADFL + Sbjct: 42 CALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYV 101 Query: 78 ICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALN 137 + LP L+ Y + DW FGD C+L F+ +N GSI+FLT ++ RY VV+P +L Sbjct: 102 LTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLG 161 Query: 138 KISNRTAAIISCLLWGI-TIGLTVHLLKKKMPIQNGGANLC----SSFSICHTFQWHEAM 192 ++ + A IS L+W I + ++ L ++ C S + F + Sbjct: 162 RLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCT 221 Query: 193 FLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVR- 251 + F +PL +IL C I+ +L + +D +++I +++V VF + ++P V++ Sbjct: 222 TVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKT 281 Query: 252 IRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINR 311 + + L C V + +T +NS +DP++Y+ + +F S + Sbjct: 282 MNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRK 341 Query: 312 CLQRKMTGEPDNNRSTSVELT 332 +R N +S S ++T Sbjct: 342 ASRRSEA----NLQSKSEDMT 358 >gi|33695097 G protein-coupled receptor 35 [Homo sapiens] Length = 309 Score = 142 bits (358), Expect = 5e-34 Identities = 93/274 (33%), Positives = 140/274 (51%), Gaps = 23/274 (8%) Query: 34 LGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDW 93 LG+ + GLL N LALW+FC ++ W +RI++ NLAVAD L+ LPF++ + D Sbjct: 27 LGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDT 86 Query: 94 KFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWG 153 C+L + NR SI +T +AVDRY V HP A S R AA + +LW Sbjct: 87 PL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWV 142 Query: 154 ITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIW 213 + IG V + + IQ GG C S H F A LL F+LPL +++FCS +++ Sbjct: 143 LVIGSLV--ARWLLGIQEGG--FCFR-STRHNFN-SMAFPLLGFYLPLAVVVFCSLKVVT 196 Query: 214 SLRQR---QMDRHAKIKRAITFIMVVAIVFVICFLP---SVVVRIRIFWLLHTSGTQNCE 267 +L QR + + ++A + +VFV+CFLP + VR+ + W C Sbjct: 197 ALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW-------NACA 249 Query: 268 VYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 + ++ A +IT + N LD + YY+ + F Sbjct: 250 LLETIRRALYITSKLSDANCCLDAICYYYMAKEF 283 >gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] Length = 346 Score = 140 bits (353), Expect = 2e-33 Identities = 89/309 (28%), Positives = 156/309 (50%), Gaps = 16/309 (5%) Query: 10 FLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNL 69 F + +NC + ++F + P V + F +G+LGNGL++++F K S +F+ NL Sbjct: 23 FSNNNSRNCTI--ENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNL 80 Query: 70 AVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRV 129 A++D L I LPF D Y+R +W FGD+ CR+M + L +N SI FLTV++V R+ + Sbjct: 81 AISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAM 140 Query: 130 VHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWH 189 VHP L+ S R+A I+ ++W + + ++ LL QNG C ++ + Sbjct: 141 VHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSE-QNGSVTSCLELNLYKIAKLQ 199 Query: 190 EAMF-------LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVI 242 + LL FF L I R++ + + ++A+T I++ I+F + Sbjct: 200 TMNYIALVVGCLLPFF-TLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFL 258 Query: 243 CFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFP 302 CFLP +R +H + + + A ITL+ N+ +P++YYF+ +F Sbjct: 259 CFLPYHTLR-----TVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFK 313 Query: 303 NFFSTLINR 311 + + + + Sbjct: 314 DRLKSALRK 322 >gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] Length = 339 Score = 134 bits (336), Expect = 2e-31 Identities = 92/289 (31%), Positives = 141/289 (48%), Gaps = 10/289 (3%) Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKF 95 L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + + W F Sbjct: 40 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 99 Query: 96 GDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGIT 155 G+I CRL F+ +N SI FLT ++ DR+ +VHP +L A + LW + Sbjct: 100 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 159 Query: 156 IGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLL--EFFLPLGIILFCSARIIW 213 LL +Q +C + H A+ L F P + C II Sbjct: 160 AVAMAPLLVSPQTVQTNHTVVC--LQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 217 Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSV 272 SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R + Sbjct: 218 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 275 Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEP 321 LA IT T +N LDP++Y+F + F + L N +++ G P Sbjct: 276 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 321 >gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] Length = 339 Score = 134 bits (336), Expect = 2e-31 Identities = 92/289 (31%), Positives = 141/289 (48%), Gaps = 10/289 (3%) Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKF 95 L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + + W F Sbjct: 40 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 99 Query: 96 GDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGIT 155 G+I CRL F+ +N SI FLT ++ DR+ +VHP +L A + LW + Sbjct: 100 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 159 Query: 156 IGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLL--EFFLPLGIILFCSARIIW 213 LL +Q +C + H A+ L F P + C II Sbjct: 160 AVAMAPLLVSPQTVQTNHTVVC--LQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 217 Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSV 272 SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R + Sbjct: 218 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 275 Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEP 321 LA IT T +N LDP++Y+F + F + L N +++ G P Sbjct: 276 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 321 >gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] Length = 367 Score = 134 bits (336), Expect = 2e-31 Identities = 92/289 (31%), Positives = 141/289 (48%), Gaps = 10/289 (3%) Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKF 95 L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + + W F Sbjct: 68 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 127 Query: 96 GDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGIT 155 G+I CRL F+ +N SI FLT ++ DR+ +VHP +L A + LW + Sbjct: 128 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 187 Query: 156 IGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLL--EFFLPLGIILFCSARIIW 213 LL +Q +C + H A+ L F P + C II Sbjct: 188 AVAMAPLLVSPQTVQTNHTVVC--LQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 245 Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSV 272 SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R + Sbjct: 246 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 303 Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEP 321 LA IT T +N LDP++Y+F + F + L N +++ G P Sbjct: 304 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 349 >gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] Length = 367 Score = 134 bits (336), Expect = 2e-31 Identities = 92/289 (31%), Positives = 141/289 (48%), Gaps = 10/289 (3%) Query: 36 LEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKF 95 L+FI L+GN LALW+F KS + +FL +LAVAD ++ LP + + W F Sbjct: 68 LDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPF 127 Query: 96 GDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGIT 155 G+I CRL F+ +N SI FLT ++ DR+ +VHP +L A + LW + Sbjct: 128 GEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV 187 Query: 156 IGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLL--EFFLPLGIILFCSARIIW 213 LL +Q +C + H A+ L F P + C II Sbjct: 188 AVAMAPLLVSPQTVQTNHTVVC--LQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIR 245 Query: 214 SLRQ-RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSV 272 SLRQ ++++ K K A+ I +V +F++CF+P V R ++ L + S +C R + Sbjct: 246 SLRQGLRVEKRLKTK-AVRMIAIVLAIFLVCFVPYHVNR-SVYVLHYRSHGASCATQRIL 303 Query: 273 DLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEP 321 LA IT T +N LDP++Y+F + F + L N +++ G P Sbjct: 304 ALANRITSCLTSLNGALDPIMYFFVAEKFRH---ALCNLLCGKRLKGPP 349 >gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] Length = 370 Score = 134 bits (336), Expect = 2e-31 Identities = 88/298 (29%), Positives = 150/298 (50%), Gaps = 13/298 (4%) Query: 17 NCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLL 76 N C+ D F + V + FI GL+ N ++L++FCF +K + IF+ NLAV+D L Sbjct: 29 NTCIVDDSFKYNLNGAVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLF 88 Query: 77 IICLPF-LMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHA 135 + LPF + N+ R W FGD C++ N GS++FLT ++VDR+ +V+P + Sbjct: 89 VCTLPFKIFYNFNRH--WPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRS 146 Query: 136 LNKISNRTAAIISCLLWGITI--GLTVHLLKKKMPIQNGGANLCSSFS--ICHTFQWHEA 191 + R +AI+ +W + + G++ L + N FS + T+ Sbjct: 147 RTIRTRRNSAIVCAGVWILVLSGGISASLF-STTNVNNATTTCFEGFSKRVWKTYLSKIT 205 Query: 192 MFL--LEFFLPLGIILFCSARIIWSLRQ--RQMDRHAKIKRAITFIMVVAIVFVICFLPS 247 +F+ + F +PL + + CS+ ++ +LR+ K+ + I V VFV+CF+P Sbjct: 206 IFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPY 265 Query: 248 VVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFF 305 V + ++ L+ + NC + R + + ITL +N DP +YYF+ SF F Sbjct: 266 NSV-LFLYALVRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSF 322 >gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 132 bits (331), Expect = 6e-31 Identities = 81/294 (27%), Positives = 144/294 (48%), Gaps = 11/294 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C + D F + + + F+ GL+ N +A++IF LK + ++ NLA++D L + Sbjct: 9 CFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVF 68 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LPF + + R +W FGD+ C++ + + N GSI+FLT ++VDR+ +V+P + Sbjct: 69 TLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTL 127 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMF----- 193 + R A I+ +W IG + + + G + F W + Sbjct: 128 RTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIF 187 Query: 194 --LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIK--RAITFIMVVAIVFVICFLPSVV 249 ++ FF+PL + + CS+ ++ +L + +KI + + I V I+F CF+P Sbjct: 188 IEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVP-YN 246 Query: 250 VRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303 + + ++ L+ T NC V +V + ITL N DP+VYYF+S + N Sbjct: 247 INLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300 >gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 132 bits (331), Expect = 6e-31 Identities = 81/294 (27%), Positives = 144/294 (48%), Gaps = 11/294 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C + D F + + + F+ GL+ N +A++IF LK + ++ NLA++D L + Sbjct: 9 CFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVF 68 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LPF + + R +W FGD+ C++ + + N GSI+FLT ++VDR+ +V+P + Sbjct: 69 TLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTL 127 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMF----- 193 + R A I+ +W IG + + + G + F W + Sbjct: 128 RTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIF 187 Query: 194 --LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIK--RAITFIMVVAIVFVICFLPSVV 249 ++ FF+PL + + CS+ ++ +L + +KI + + I V I+F CF+P Sbjct: 188 IEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVP-YN 246 Query: 250 VRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303 + + ++ L+ T NC V +V + ITL N DP+VYYF+S + N Sbjct: 247 INLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300 >gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 132 bits (331), Expect = 6e-31 Identities = 81/294 (27%), Positives = 144/294 (48%), Gaps = 11/294 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C + D F + + + F+ GL+ N +A++IF LK + ++ NLA++D L + Sbjct: 9 CFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVF 68 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LPF + + R +W FGD+ C++ + + N GSI+FLT ++VDR+ +V+P + Sbjct: 69 TLPFRIFYFTTR-NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTL 127 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMF----- 193 + R A I+ +W IG + + + G + F W + Sbjct: 128 RTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIF 187 Query: 194 --LLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIK--RAITFIMVVAIVFVICFLPSVV 249 ++ FF+PL + + CS+ ++ +L + +KI + + I V I+F CF+P Sbjct: 188 IEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVP-YN 246 Query: 250 VRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPN 303 + + ++ L+ T NC V +V + ITL N DP+VYYF+S + N Sbjct: 247 INLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN 300 >gi|4557359 bradykinin receptor B2 [Homo sapiens] Length = 391 Score = 131 bits (330), Expect = 8e-31 Identities = 88/284 (30%), Positives = 142/284 (50%), Gaps = 14/284 (4%) Query: 29 VLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYV 88 + PP L + F+ L N L +FC H S + I+L NLA AD +L LPF Sbjct: 59 IQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITIS 118 Query: 89 RRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIIS 148 +DW FG+ CR++ +++MN SI FL +V++DRY +V R A + S Sbjct: 119 NNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYS 178 Query: 149 CLLWGITIGLTVHLL--KKKMPIQNGGANLCSSFSICHTFQW----HEAMFLLEFFLPLG 202 ++WG T+ L+ +L + + G N+ + + W + + ++ F LPL Sbjct: 179 LVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLS 238 Query: 203 IILFCSARIIWSLRQRQMDRHAKI---KRAITFIMVVAIVFVICFLPSVVVRIRIFW-LL 258 +I FC+ +I+ LR +M + +I +RA ++VV ++F+IC+LP +I F L Sbjct: 239 VITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLP---FQISTFLDTL 295 Query: 259 HTSG-TQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 H G +C+ R +D+ I Y NS L+P+VY F Sbjct: 296 HRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRF 339 >gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] Length = 337 Score = 127 bits (318), Expect = 2e-29 Identities = 87/305 (28%), Positives = 140/305 (45%), Gaps = 11/305 (3%) Query: 11 LEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFC--FHLKSWKSSRIFLFN 68 L + C DDF +V + + + G GNG L++ +H KS + ++++ N Sbjct: 7 LTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKS--AFQVYMIN 64 Query: 69 LAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFR 128 LAVAD L + LP + YV + W FGD CRL + L +N SI F+T ++ R Sbjct: 65 LAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIA 124 Query: 129 VVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLC-----SSFSIC 183 +V P +N ++ + A + +W I + L K C + + Sbjct: 125 IVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKN 184 Query: 184 HTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRH-AKIKRAITFIMVVAIVFVI 242 H H + F +P II+ C II +L ++ M ++ + K+AI IMVV F++ Sbjct: 185 HVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLV 244 Query: 243 CFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFP 302 F+P + R LH T+ C+ + + ITLS N DP++Y+FS +F Sbjct: 245 SFMPYHIQRTIHLHFLHNE-TKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFR 303 Query: 303 NFFST 307 ST Sbjct: 304 KRLST 308 >gi|28872720 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 126 bits (317), Expect = 3e-29 Identities = 87/294 (29%), Positives = 134/294 (45%), Gaps = 10/294 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C F +DF +LP G+ + GL N +AL+IF LK+W +S ++F+LAV+D L Sbjct: 25 CRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAA 84 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ Y R W F + C+L+ F+ N SI+FLT ++V R V+ P +L Sbjct: 85 SLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRW 144 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQ----WHEAMFL 194 R A ++ +W + + +L GG C S F + M Sbjct: 145 GRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLG 204 Query: 195 LEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRA----ITFIMVVAIVFVICFLPSVVV 250 L F +P +IL C + L + + RA + I VV VF +CFLP V Sbjct: 205 LLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVT 264 Query: 251 RIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304 R + S +C ++++A+ +T NS LDPV+Y+ + F Sbjct: 265 --RTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRF 316 >gi|28872745 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 126 bits (317), Expect = 3e-29 Identities = 87/294 (29%), Positives = 134/294 (45%), Gaps = 10/294 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C F +DF +LP G+ + GL N +AL+IF LK+W +S ++F+LAV+D L Sbjct: 25 CRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAA 84 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ Y R W F + C+L+ F+ N SI+FLT ++V R V+ P +L Sbjct: 85 SLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRW 144 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQ----WHEAMFL 194 R A ++ +W + + +L GG C S F + M Sbjct: 145 GRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLG 204 Query: 195 LEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRA----ITFIMVVAIVFVICFLPSVVV 250 L F +P +IL C + L + + RA + I VV VF +CFLP V Sbjct: 205 LLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVT 264 Query: 251 RIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304 R + S +C ++++A+ +T NS LDPV+Y+ + F Sbjct: 265 --RTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRF 316 >gi|28872743 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 126 bits (317), Expect = 3e-29 Identities = 87/294 (29%), Positives = 134/294 (45%), Gaps = 10/294 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C F +DF +LP G+ + GL N +AL+IF LK+W +S ++F+LAV+D L Sbjct: 25 CRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAA 84 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ Y R W F + C+L+ F+ N SI+FLT ++V R V+ P +L Sbjct: 85 SLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRW 144 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQ----WHEAMFL 194 R A ++ +W + + +L GG C S F + M Sbjct: 145 GRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLG 204 Query: 195 LEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRA----ITFIMVVAIVFVICFLPSVVV 250 L F +P +IL C + L + + RA + I VV VF +CFLP V Sbjct: 205 LLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVT 264 Query: 251 RIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNF 304 R + S +C ++++A+ +T NS LDPV+Y+ + F Sbjct: 265 --RTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRF 316 >gi|34577052 coagulation factor II (thrombin) receptor-like 1 precursor [Homo sapiens] Length = 397 Score = 125 bits (313), Expect = 8e-29 Identities = 88/298 (29%), Positives = 147/298 (49%), Gaps = 16/298 (5%) Query: 13 IDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVA 72 +D+ + V LP V + F+ GL NG+ALW+F F K + I++ NLA+A Sbjct: 61 VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA 120 Query: 73 DFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHP 132 D L +I P + ++ +W +G+ C +++ N SI+F+T ++V RY+ +V+P Sbjct: 121 DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP 180 Query: 133 HHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAM 192 K +N A IS +W + + +T+ L K I N+ + + M Sbjct: 181 MGHSRKKAN-IAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDM 239 Query: 193 FLLEFFLPLGIILF-----CSARI--IWSLRQRQMDRHA--KIKRAITFIMVVAIVFVIC 243 F L +G+ LF SA + I LR MD ++ K KRAI I+ V +++IC Sbjct: 240 FNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLIC 299 Query: 244 FLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 F PS ++ + ++L+ + G + V + + L + +NS +DP VYYF S F Sbjct: 300 FTPSNLLLVVHYFLIKSQGQSH------VYALYIVALCLSTLNSCIDPFVYYFVSHDF 351 >gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] Length = 365 Score = 124 bits (311), Expect = 1e-28 Identities = 83/290 (28%), Positives = 136/290 (46%), Gaps = 10/290 (3%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 C F +DF +LP + F+ GL N LW+F F L+ W ++ ++F+LA++D L ++ Sbjct: 27 CWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVL 86 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ Y W FG C+ + F+ N S++FLT ++V RY + HP AL Sbjct: 87 SLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRW 146 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFS----ICHTFQWHEAMFL 194 R A ++ +W + G V L G LC + H + A+ Sbjct: 147 GRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMG 206 Query: 195 LEFFLPLGIILFC---SARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVR 251 L F +P + L C AR ++ +++ R++ I VV VF +CF+P + R Sbjct: 207 LLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRL-RSLRTIAVVLTVFAVCFVPFHITR 265 Query: 252 IRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 I++L +C V V++ + +T NS LDPV+Y + + Sbjct: 266 -TIYYLARLL-EADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKY 313 >gi|47271392 succinate receptor 1 [Homo sapiens] Length = 334 Score = 123 bits (309), Expect = 2e-28 Identities = 77/276 (27%), Positives = 142/276 (51%), Gaps = 13/276 (4%) Query: 35 GLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWK 94 G+EF+ G+LGN + ++ + F LK+W SS I+LFNL+V+D + LP L+ +Y +W Sbjct: 31 GIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYA-NGNWI 89 Query: 95 FGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHP--HHALNKISNRTAAIISCLLW 152 +GD+ C ++L N SI+FLT +++DRY + +P H L K A +IS +W Sbjct: 90 YGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQK--KEFAILISLAIW 147 Query: 153 GITIGLTVHLLKKKMPIQNGGANLCSSFSIC----HTFQWHEAMFLLEFFLPLGIILFCS 208 + + +L P+ C+ F+ + + + LL F +PL ++ F Sbjct: 148 VLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFY 207 Query: 209 ARIIWSLRQ--RQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVR-IRIFWLLHTSGTQN 265 +I L+Q RQ+ +++ + +++ ++F + F P V+R +RI L + Sbjct: 208 YKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQ 267 Query: 266 CEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 C ++ + +T ++NS+++PV Y+ F Sbjct: 268 C-TQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHF 302 >gi|4506241 platelet-activating factor receptor [Homo sapiens] Length = 342 Score = 123 bits (309), Expect = 2e-28 Identities = 89/319 (27%), Positives = 147/319 (46%), Gaps = 32/319 (10%) Query: 24 DFIVKVLPPVLGLEFIFGLLGNGLALWIFC--FHLKSWKSSRIFLFNLAVADFLLIICLP 81 +F + P V + F+ G++ NG LW+F + K + +IF+ NL +AD L +I LP Sbjct: 12 EFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLP 71 Query: 82 FLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISN 141 + Y + +W C + + +N S+ FL V+ +R+ V P + Sbjct: 72 LWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTR 131 Query: 142 RTAAIISCLLWGITIGLTVHLL----KKKMPIQNGGANLCSSFS----------ICHTFQ 187 + +S ++W +G + L +P G N+ F I H F Sbjct: 132 KRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIF- 190 Query: 188 WHEAMFLLEFFLPLGIILFCSARIIWSLRQR--QMDRHAKIK-RAITFIMVVAIVFVICF 244 + FFL IILFC+ II +L + Q R+A++K RA+ + V VF+ICF Sbjct: 191 -----IVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICF 245 Query: 245 LPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF--- 301 +P VV++ W L G Q+ + +++++ A +TL N +LDPV+Y F + F Sbjct: 246 VPHHVVQLP--WTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKH 303 Query: 302 --PNFFSTLINRCLQRKMT 318 F+S +R R T Sbjct: 304 LTEKFYSMRSSRKCSRATT 322 >gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 122 bits (307), Expect = 4e-28 Identities = 86/297 (28%), Positives = 133/297 (44%), Gaps = 20/297 (6%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 CV+R++F +LPPV GL N + C ++ + ++ NLA+AD L Sbjct: 18 CVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYAC 77 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ NY + W FGD CRL+ F+ N GSI+FLT ++ RY + HP +K Sbjct: 78 SLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNG---GANLCSSFS----ICHTFQWHEA 191 R AA + C+ + + +T L + G +C S H + A Sbjct: 138 RGGRRAAWLVCV--AVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMA 195 Query: 192 MFLLEFFLPLGIILFCSARIIWSLRQRQ-------MDRHAKIKRAITFIMVVAIVFVICF 244 + ++ F LP +L C + L ++ +R K R +VVA F I F Sbjct: 196 LTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAAR---MAVVVAAAFAISF 252 Query: 245 LPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 LP + + + T G C V + A+ T F NS+LDP+++YF+ F Sbjct: 253 LPFHITKTAYLAVRSTPGVP-CTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKF 308 >gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 122 bits (307), Expect = 4e-28 Identities = 86/297 (28%), Positives = 133/297 (44%), Gaps = 20/297 (6%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 CV+R++F +LPPV GL N + C ++ + ++ NLA+AD L Sbjct: 18 CVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYAC 77 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ NY + W FGD CRL+ F+ N GSI+FLT ++ RY + HP +K Sbjct: 78 SLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNG---GANLCSSFS----ICHTFQWHEA 191 R AA + C+ + + +T L + G +C S H + A Sbjct: 138 RGGRRAAWLVCV--AVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMA 195 Query: 192 MFLLEFFLPLGIILFCSARIIWSLRQRQ-------MDRHAKIKRAITFIMVVAIVFVICF 244 + ++ F LP +L C + L ++ +R K R +VVA F I F Sbjct: 196 LTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAAR---MAVVVAAAFAISF 252 Query: 245 LPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 LP + + + T G C V + A+ T F NS+LDP+++YF+ F Sbjct: 253 LPFHITKTAYLAVRSTPGVP-CTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKF 308 >gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 122 bits (307), Expect = 4e-28 Identities = 86/297 (28%), Positives = 133/297 (44%), Gaps = 20/297 (6%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 CV+R++F +LPPV GL N + C ++ + ++ NLA+AD L Sbjct: 18 CVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYAC 77 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ NY + W FGD CRL+ F+ N GSI+FLT ++ RY + HP +K Sbjct: 78 SLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNG---GANLCSSFS----ICHTFQWHEA 191 R AA + C+ + + +T L + G +C S H + A Sbjct: 138 RGGRRAAWLVCV--AVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMA 195 Query: 192 MFLLEFFLPLGIILFCSARIIWSLRQRQ-------MDRHAKIKRAITFIMVVAIVFVICF 244 + ++ F LP +L C + L ++ +R K R +VVA F I F Sbjct: 196 LTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAAR---MAVVVAAAFAISF 252 Query: 245 LPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 LP + + + T G C V + A+ T F NS+LDP+++YF+ F Sbjct: 253 LPFHITKTAYLAVRSTPGVP-CTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKF 308 >gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 122 bits (307), Expect = 4e-28 Identities = 86/297 (28%), Positives = 133/297 (44%), Gaps = 20/297 (6%) Query: 19 CVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLII 78 CV+R++F +LPPV GL N + C ++ + ++ NLA+AD L Sbjct: 18 CVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYAC 77 Query: 79 CLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNK 138 LP L+ NY + W FGD CRL+ F+ N GSI+FLT ++ RY + HP +K Sbjct: 78 SLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137 Query: 139 ISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNG---GANLCSSFS----ICHTFQWHEA 191 R AA + C+ + + +T L + G +C S H + A Sbjct: 138 RGGRRAAWLVCV--AVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMA 195 Query: 192 MFLLEFFLPLGIILFCSARIIWSLRQRQ-------MDRHAKIKRAITFIMVVAIVFVICF 244 + ++ F LP +L C + L ++ +R K R +VVA F I F Sbjct: 196 LTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAAR---MAVVVAAAFAISF 252 Query: 245 LPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301 LP + + + T G C V + A+ T F NS+LDP+++YF+ F Sbjct: 253 LPFHITKTAYLAVRSTPGVP-CTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKF 308 >gi|149944554 somatostatin receptor 4 [Homo sapiens] Length = 388 Score = 122 bits (305), Expect = 7e-28 Identities = 87/298 (29%), Positives = 143/298 (47%), Gaps = 37/298 (12%) Query: 33 VLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWD 92 + L + GL+GN L +++ + K ++ I+L NLAVAD L ++ +PF+ + R Sbjct: 53 IYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALR-H 111 Query: 93 WKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLW 152 W FG + CR +L + +N S+ LTV++VDRY VVHP A A +I+ +W Sbjct: 112 WPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVW 171 Query: 153 --GITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQW-HEA--------MFLLEFFLPL 201 + + L + + P + G A C+ QW H A FLL F LP+ Sbjct: 172 LASLLVTLPIAIFADTRPARGGQAVACN-------LQWPHPAWSAVFVVYTFLLGFLLPV 224 Query: 202 GIILFCSARIIW-----SLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFW 256 I C I+ +LR R K+ +++V +VFV+C++P VV++ + Sbjct: 225 LAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLF 284 Query: 257 LLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQ 314 + T N ++L +Y NS +P++Y F S +F FF ++ CL+ Sbjct: 285 VTSLDATVN-----------HVSLILSYANSCANPILYGFLSDNFRRFFQRVL--CLR 329 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.332 0.143 0.473 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,699,676 Number of Sequences: 37866 Number of extensions: 570139 Number of successful extensions: 2919 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 316 Number of HSP's successfully gapped in prelim test: 173 Number of HSP's that attempted gapping in prelim test: 1914 Number of HSP's gapped (non-prelim): 600 length of query: 363 length of database: 18,247,518 effective HSP length: 104 effective length of query: 259 effective length of database: 14,309,454 effective search space: 3706148586 effective search space used: 3706148586 T: 11 A: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.