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Search of human proteins with 28373086
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
(413 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 833 0.0
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 822 0.0
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 816 0.0
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 681 0.0
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 678 0.0
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 630 0.0
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 425 e-119
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 231 9e-61
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 231 9e-61
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 198 7e-51
gi|28373072 sialyltransferase 6 isoform c [Homo sapiens] 194 9e-50
gi|28373076 sialyltransferase 6 isoform e [Homo sapiens] 192 6e-49
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 192 6e-49
gi|28373084 sialyltransferase 6 isoform h [Homo sapiens] 144 2e-34
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 115 6e-26
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 115 6e-26
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 104 1e-22
gi|21264332 sialyltransferase 7A [Homo sapiens] 97 3e-20
gi|192448440 sialyltransferase 7B [Homo sapiens] 80 3e-15
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 69 6e-12
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 69 6e-12
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 65 1e-10
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 64 3e-10
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 60 5e-09
gi|13569938 sialyltransferase 7E [Homo sapiens] 60 5e-09
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 59 8e-09
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 59 8e-09
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 58 1e-08
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 55 2e-07
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 54 3e-07
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 833 bits (2153), Expect = 0.0
Identities = 413/413 (100%), Positives = 413/413 (100%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
Query: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANFS 120
TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANFS
Sbjct: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANFS 120
Query: 121 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV 180
EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV
Sbjct: 121 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV 180
Query: 181 TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 240
TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK
Sbjct: 181 TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 240
Query: 241 TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRV 300
TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRV
Sbjct: 241 TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRV 300
Query: 301 PKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF 360
PKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF
Sbjct: 301 PKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF 360
Query: 361 GYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413
GYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 361 GYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 822 bits (2122), Expect = 0.0
Identities = 412/429 (96%), Positives = 413/429 (96%), Gaps = 16/429 (3%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL 44
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS +YDRL
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL 60
Query: 45 GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFL 104
GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFL
Sbjct: 61 GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFL 120
Query: 105 KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP 164
KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
Sbjct: 121 KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP 180
Query: 165 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 224
FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
Sbjct: 181 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 240
Query: 225 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 284
LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
Sbjct: 241 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 300
Query: 285 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA 344
RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
Sbjct: 301 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA 360
Query: 345 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR 404
VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
Sbjct: 361 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR 420
Query: 405 VITDLSSGI 413
VITDLSSGI
Sbjct: 421 VITDLSSGI 429
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 816 bits (2107), Expect = 0.0
Identities = 412/444 (92%), Positives = 413/444 (93%), Gaps = 31/444 (6%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS--------------------- 39
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
Query: 40 ----------KYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 89
+YDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI
Sbjct: 61 FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
Query: 90 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 149
LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
Query: 150 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 209
DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
Query: 210 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 269
KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
Query: 270 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 329
KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
Query: 330 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 389
GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
Query: 390 IQREKEFLRKLVKARVITDLSSGI 413
IQREKEFLRKLVKARVITDLSSGI
Sbjct: 421 IQREKEFLRKLVKARVITDLSSGI 444
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 681 bits (1757), Expect = 0.0
Identities = 357/414 (86%), Positives = 361/414 (87%), Gaps = 25/414 (6%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS-KYDRLGFLLNLDSKLSPRTL 59
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS KY + S
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYS------HSSSPQEKPVA 54
Query: 60 CTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANF 119
+VV D S G+ L S + F L L PAELATKYANF
Sbjct: 55 DSVVLSFD----SAGQT-------------LGSEYDRLGFLLN-LDSKLPAELATKYANF 96
Query: 120 SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILS 179
SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILS
Sbjct: 97 SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILS 156
Query: 180 VTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239
VTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS
Sbjct: 157 VTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216
Query: 240 KTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATR 299
KTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATR
Sbjct: 217 KTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATR 276
Query: 300 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 359
VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG
Sbjct: 277 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 336
Query: 360 FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413
FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 337 FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 390
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 678 bits (1750), Expect = 0.0
Identities = 353/413 (85%), Positives = 356/413 (86%), Gaps = 38/413 (9%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS L F
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSF-------------- 46
Query: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANFS 120
+S G+ L S + F L L PAELATKYANFS
Sbjct: 47 ----------DSAGQT-------------LGSEYDRLGFLLN-LDSKLPAELATKYANFS 82
Query: 121 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV 180
EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV
Sbjct: 83 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV 142
Query: 181 TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 240
TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK
Sbjct: 143 TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 202
Query: 241 TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRV 300
TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRV
Sbjct: 203 TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRV 262
Query: 301 PKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF 360
PKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF
Sbjct: 263 PKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF 322
Query: 361 GYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413
GYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 323 GYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 375
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 630 bits (1625), Expect = 0.0
Identities = 339/419 (80%), Positives = 341/419 (81%), Gaps = 66/419 (15%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
MGLLVFVRNLLLALCLFLV LGFL KL
Sbjct: 1 MGLLVFVRNLLLALCLFLV------------------------LGFLYYSAWKLH----- 31
Query: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAF-ALGFL-----KLPRPAELAT 114
L ED+ + LGFL KLP AELAT
Sbjct: 32 -----------------------------LLQWEEDSKYDRLGFLLNLDSKLP--AELAT 60
Query: 115 KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI 174
KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI
Sbjct: 61 KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI 120
Query: 175 KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE 234
KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE
Sbjct: 121 KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE 180
Query: 235 KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK 294
KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK
Sbjct: 181 KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK 240
Query: 295 SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE 354
SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE
Sbjct: 241 SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE 300
Query: 355 VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413
VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 301 VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 359
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 425 bits (1092), Expect = e-119
Identities = 227/287 (79%), Positives = 230/287 (80%), Gaps = 38/287 (13%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS L F
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSF-------------- 46
Query: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANFS 120
+S G+ L S + F L L PAELATKYANFS
Sbjct: 47 ----------DSAGQT-------------LGSEYDRLGFLLN-LDSKLPAELATKYANFS 82
Query: 121 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV 180
EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV
Sbjct: 83 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSV 142
Query: 181 TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 240
TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK
Sbjct: 143 TKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 202
Query: 241 TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS 287
TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS
Sbjct: 203 TTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS 249
Score = 60.8 bits (146), Expect = 2e-09
Identities = 29/29 (100%), Positives = 29/29 (100%)
Query: 385 SWTHNIQREKEFLRKLVKARVITDLSSGI 413
SWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 249 SWTHNIQREKEFLRKLVKARVITDLSSGI 277
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 231 bits (589), Expect = 9e-61
Identities = 125/313 (39%), Positives = 187/313 (59%), Gaps = 6/313 (1%)
Query: 107 PRPAELATKYAN-FSEGACKPGYASALMTAIFP-RFSKPAPMFLDDSFRKWARIREFVPP 164
P + A KYA + C+P +A M +F R+S F+ + + ++ PP
Sbjct: 79 PDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPP 138
Query: 165 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 224
FG + + ++ +L + E+ L L + CRRC+++G+GG+L LG ++ +D+V+R
Sbjct: 139 FGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIR 198
Query: 225 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 284
LNSAPV+G+ + VG+KTT+R+TYPEGA +Y + LFV FK DF WL+ +V KE
Sbjct: 199 LNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKE 258
Query: 285 RVS--ASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPF-NNGLMGRG-NIPTL 340
+ FWK VA ++P +P RILNP I+E AF ++ + GR N+PT+
Sbjct: 259 TLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTI 318
Query: 341 GSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 400
G +AV +A H CDEV++AGFGYD++ P PLHY+++ MAA+ HN+ E +FL KL
Sbjct: 319 GVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKL 378
Query: 401 VKARVITDLSSGI 413
VK V+ DLS GI
Sbjct: 379 VKEGVVKDLSGGI 391
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 231 bits (589), Expect = 9e-61
Identities = 125/313 (39%), Positives = 187/313 (59%), Gaps = 6/313 (1%)
Query: 107 PRPAELATKYAN-FSEGACKPGYASALMTAIFP-RFSKPAPMFLDDSFRKWARIREFVPP 164
P + A KYA + C+P +A M +F R+S F+ + + ++ PP
Sbjct: 102 PDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPP 161
Query: 165 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 224
FG + + ++ +L + E+ L L + CRRC+++G+GG+L LG ++ +D+V+R
Sbjct: 162 FGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIR 221
Query: 225 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 284
LNSAPV+G+ + VG+KTT+R+TYPEGA +Y + LFV FK DF WL+ +V KE
Sbjct: 222 LNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKE 281
Query: 285 RVS--ASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPF-NNGLMGRG-NIPTL 340
+ FWK VA ++P +P RILNP I+E AF ++ + GR N+PT+
Sbjct: 282 TLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTI 341
Query: 341 GSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 400
G +AV +A H CDEV++AGFGYD++ P PLHY+++ MAA+ HN+ E +FL KL
Sbjct: 342 GVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKL 401
Query: 401 VKARVITDLSSGI 413
VK V+ DLS GI
Sbjct: 402 VKEGVVKDLSGGI 414
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 198 bits (504), Expect = 7e-51
Identities = 112/291 (38%), Positives = 171/291 (58%), Gaps = 7/291 (2%)
Query: 124 CKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIRE-FVPPFGIKGQDNLIKAILSVTK 182
C G A + + +F +S+ P+FL W + + P+G KG ++L+ +L++T
Sbjct: 42 CLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITS 101
Query: 183 EYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTT 242
+ + SLRCRRC++VGNG L N SLG I+ YD+V+RLN+APV G+E DVGSKTT
Sbjct: 102 S-SIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTT 160
Query: 243 LRITYPEGAMQRPE-QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 301
+R+ YPE A P+ + D+L VL FK DF W++ I+ ++ GFWK
Sbjct: 161 MRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETIL-SDKKRVRKGFWKQPPLIWD 219
Query: 302 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 361
P +IRILNP+F++ AA L+ LP + PT G +A+T+ALH CD V +AGFG
Sbjct: 220 VNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQK-PTTGLLAITLALHLCDLVHIAGFG 278
Query: 362 Y-DMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSS 411
Y D +HYYE + + ++ S HN+ +E ++++++ I +L+S
Sbjct: 279 YPDAYNKKQTIHYYEQITLKSMAGS-GHNVSQEALAIKRMLEMGAIKNLTS 328
>gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]
Length = 170
Score = 194 bits (494), Expect = 9e-50
Identities = 114/171 (66%), Positives = 118/171 (69%), Gaps = 25/171 (14%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS-KYDRLGFLLNLDSKLSPRTL 59
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS KY + S
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYS------HSSSPQEKPVA 54
Query: 60 CTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANF 119
+VV D S G+ L S + F L L PAELATKYANF
Sbjct: 55 DSVVLSFD----SAGQT-------------LGSEYDRLGFLLN-LDSKLPAELATKYANF 96
Query: 120 SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 170
SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 97 SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 147
>gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]
Length = 155
Score = 192 bits (487), Expect = 6e-49
Identities = 110/170 (64%), Positives = 113/170 (66%), Gaps = 38/170 (22%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS L F
Sbjct: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSF-------------- 46
Query: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANFS 120
+S G+ L S + F L L PAELATKYANFS
Sbjct: 47 ----------DSAGQT-------------LGSEYDRLGFLLN-LDSKLPAELATKYANFS 82
Query: 121 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 170
EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 83 EGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 132
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 192 bits (487), Expect = 6e-49
Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)
Query: 125 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 181
KP +AS L RF + P FRK A + +F P+G++ + LS
Sbjct: 48 KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101
Query: 182 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 241
+ L D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161
Query: 242 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 301
T R+ YPE P + ++ +L FK D +WL ++ ++++ ++GFWK A +
Sbjct: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220
Query: 302 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 361
+P +IRIL+P+ I+ AA+ L+ P + PT G +A+T+A + C EV +AGF
Sbjct: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280
Query: 362 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 410
Y+ S +PLHYY M+ + ++ HN+ E+ FL+ +++ ++ +L+
Sbjct: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329
>gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]
Length = 139
Score = 144 bits (362), Expect = 2e-34
Identities = 96/176 (54%), Positives = 98/176 (55%), Gaps = 66/176 (37%)
Query: 1 MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60
MGLLVFVRNLLLALCLFLV LGFL KL
Sbjct: 1 MGLLVFVRNLLLALCLFLV------------------------LGFLYYSAWKLH----- 31
Query: 61 TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAF-ALGFL-----KLPRPAELAT 114
L ED+ + LGFL KLP AELAT
Sbjct: 32 -----------------------------LLQWEEDSKYDRLGFLLNLDSKLP--AELAT 60
Query: 115 KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 170
KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 61 KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 116
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 115 bits (289), Expect = 6e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 149 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 206
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
Query: 207 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 266
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
Query: 267 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 326
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
Query: 327 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 385
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
Query: 386 WTHNIQREKEFLRKLVKARVI 406
H+ E L I
Sbjct: 314 GVHDADFESNVTATLASINKI 334
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 115 bits (289), Expect = 6e-26
Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)
Query: 149 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 206
DD++R W R++ P + ++ IK + V + P L+ S+ CRRC +VGN G
Sbjct: 95 DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150
Query: 207 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 266
L S G ID +D V+R+N AP GFE DVG+KTT + YPE + + +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206
Query: 267 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 326
FK D +W+ + +S + + V ++ + +I I +P FI+
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255
Query: 327 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 385
F+N L G G P+ G ++V ++H CDEV + GFG D + HY+E A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313
Query: 386 WTHNIQREKEFLRKLVKARVI 406
H+ E L I
Sbjct: 314 GVHDADFESNVTATLASINKI 334
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 104 bits (260), Expect = 1e-22
Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 191 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 250
D +CRRC +VGN G L G +D ++ ++R+N AP GFE+DVGS+TT YPE
Sbjct: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204
Query: 251 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 310
A P FVL FK D W+ + ++ + KS RV KE +++I
Sbjct: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257
Query: 311 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 370
NP F + + G P+ G + + ALH CDEV V GFG D S N
Sbjct: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308
Query: 371 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 406
HY+E R A +++ H+ E + L KA I
Sbjct: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 97.1 bits (240), Expect = 3e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 146 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 195
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
Query: 196 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 243
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
Query: 244 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 299
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
Query: 300 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 359
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
Query: 360 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 400
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 155 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 208
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
Query: 209 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 256
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
Query: 257 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 312
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
Query: 313 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 372
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
Query: 373 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 406
Y+E +M + H++ E R L KA ++
Sbjct: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 69.3 bits (168), Expect = 6e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 185 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
Query: 240 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 296
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
Query: 297 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 356
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
Query: 357 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 400
V + Y S L HY+E AA H + EK +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 69.3 bits (168), Expect = 6e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 185 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
Query: 240 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 296
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
Query: 297 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 356
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
Query: 357 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 400
V + Y S L HY+E AA H + EK +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 65.1 bits (157), Expect = 1e-10
Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)
Query: 185 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
Query: 240 KTTLRI 245
KTT+RI
Sbjct: 338 KTTIRI 343
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 63.9 bits (154), Expect = 3e-10
Identities = 58/242 (23%), Positives = 98/242 (40%), Gaps = 48/242 (19%)
Query: 184 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 240
Y L P L+ + C IVGN GVL N G ID + V+R N APV+ + +DVG K
Sbjct: 140 YELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLK 199
Query: 241 TTL----------------RITYPEGAMQRPEQYERDSLFV---LAGFKWQDFKWLKYIV 281
T L T+ E +QR L++ +A + +W+ ++
Sbjct: 200 TDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELI 259
Query: 282 YKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLG 341
K V+ + P +R+L+ + G N + + PT G
Sbjct: 260 LKHHVNVRTAY------------PSLRLLH---------AVRGYWLTNKVHIKR--PTTG 296
Query: 342 SVAVTMALHGCDEVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR 398
+ T+A C ++ + G F D + HYY++++ ++ H + E + L+
Sbjct: 297 LLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALK 356
Query: 399 KL 400
L
Sbjct: 357 SL 358
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 59.7 bits (143), Expect = 5e-09
Identities = 49/200 (24%), Positives = 82/200 (41%), Gaps = 30/200 (15%)
Query: 195 CRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQR 254
CR C +V + G + LG+ ID + V R+N AP GFE DVG ++TLR+
Sbjct: 73 CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 132
Query: 255 PEQYE------RDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIR 308
Y RD+L+++ W + + ++ G ++ + P ++
Sbjct: 133 LRNYSHYFQKARDTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQ 180
Query: 309 ILNPYFIQEAAFTLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD- 363
+ Y E F + G+ + G + +AL C+E+ V G D
Sbjct: 181 V---YTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237
Query: 364 ----MSTPNAPLHYYETVRM 379
S P+ P HY+E R+
Sbjct: 238 YCREKSHPSVPYHYFEKGRL 257
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 59.7 bits (143), Expect = 5e-09
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)
Query: 193 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 252
+ CR C +V + G L + GS+ID + V+R+N AP +G+ +DVG++T+LR+ ++
Sbjct: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149
Query: 253 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 305
QR + D L V G W ++ K VY S + A + +
Sbjct: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207
Query: 306 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 360
++ + F QE T +N + + G +T+AL CD + V G F
Sbjct: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258
Query: 361 GYDMSTPNAPLHYYE 375
D + P+ P HYYE
Sbjct: 259 CRDPNHPSVPYHYYE 273
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 58.9 bits (141), Expect = 8e-09
Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 197 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 256
RC +V + G L + LG IDD+D V+R N AP F++DVG+KTT+R+ + + +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241
Query: 257 QYERDSLF 264
++ +DSL+
Sbjct: 242 RFLKDSLY 249
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 58.9 bits (141), Expect = 8e-09
Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 197 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 256
RC +V + G L + LG IDD+D V+R N AP F++DVG+KTT+R+ + + +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241
Query: 257 QYERDSLF 264
++ +DSL+
Sbjct: 242 RFLKDSLY 249
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/230 (24%), Positives = 94/230 (40%), Gaps = 24/230 (10%)
Query: 184 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 240
+ L P + ++ RR C +VGN G+L + G ID ++ V+R N APV F DVG+K
Sbjct: 125 HSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTK 184
Query: 241 TTLRITYPEGAMQRP-----EQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKS 295
+ IT +QR + +R+ W+ + V + +
Sbjct: 185 SDF-ITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFM----VKGGEKHVEW 239
Query: 296 VATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNI--PTLGSVAVTMALHGCD 353
V + K ++R P + LI L + I P+ G + T+A CD
Sbjct: 240 VNALILKNKLKVRTAYP------SLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCD 293
Query: 354 EVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 400
E+ + G F D++ HYY+ ++ + H + E + L L
Sbjct: 294 EIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVL 343
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)
Query: 175 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 230
K + S++ +R L P + + + C +VGN G+L G ID D V R N AP
Sbjct: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194
Query: 231 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 285
+ F++DVG KT L T+ +++ +R++ F+ W+ +
Sbjct: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253
Query: 286 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 336
+ + R L +F++ + L + +M N
Sbjct: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
Query: 337 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 390
+ G + T+A C+E+ + G FG+D +T + P HYY+ + W +
Sbjct: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354
Query: 391 QREKEF 396
Q EF
Sbjct: 355 QLPAEF 360
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 53.9 bits (128), Expect = 3e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 193 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 251
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
Query: 252 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 311
QR + + K + ++ + + + N
Sbjct: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
Query: 312 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 370
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
Query: 371 L--HYYETV 377
+ HYY+ V
Sbjct: 307 ISHHYYDNV 315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,261,570
Number of Sequences: 37866
Number of extensions: 734021
Number of successful extensions: 1399
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1321
Number of HSP's gapped (non-prelim): 58
length of query: 413
length of database: 18,247,518
effective HSP length: 105
effective length of query: 308
effective length of database: 14,271,588
effective search space: 4395649104
effective search space used: 4395649104
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.