Search of human proteins with 28373082

Search of human proteins with 28373082

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
         (359 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]              727   0.0  
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]               715   0.0  
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]              709   0.0  
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]              684   0.0  
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]              678   0.0  
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]              630   0.0  
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]              461   e-130
gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]              240   1e-63
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...   231   1e-60
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...   231   1e-60
gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]              228   5e-60
gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]              223   3e-58
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H...   198   5e-51
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]               193   2e-49
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [...   115   5e-26
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H...   115   5e-26
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H...   104   1e-22
gi|21264332 sialyltransferase 7A [Homo sapiens]                        97   2e-20
gi|192448440 sialyltransferase 7B [Homo sapiens]                       80   3e-15
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    69   5e-12
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ...    69   5e-12
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    65   9e-11
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    64   2e-10
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]              60   4e-09
gi|13569938 sialyltransferase 7E [Homo sapiens]                        60   4e-09
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i...    59   7e-09
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ...    59   7e-09
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    58   1e-08
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran...    55   1e-07
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]                54   2e-07

>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
          Length = 359

 Score =  727 bits (1876), Expect = 0.0
 Identities = 359/359 (100%), Positives = 359/359 (100%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELAT 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELAT
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELAT 60

Query: 61  KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI 120
           KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI
Sbjct: 61  KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI 120

Query: 121 KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE 180
           KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE
Sbjct: 121 KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE 180

Query: 181 KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK 240
           KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK
Sbjct: 181 KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK 240

Query: 241 SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE 300
           SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE
Sbjct: 241 SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE 300

Query: 301 VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 359
           VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 301 VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 359


>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
          Length = 375

 Score =  715 bits (1845), Expect = 0.0
 Identities = 358/375 (95%), Positives = 359/375 (95%), Gaps = 16/375 (4%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL 44
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS                +YDRL
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL 60

Query: 45  GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI 104
           GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
Sbjct: 61  GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI 120

Query: 105 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD 164
           REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
Sbjct: 121 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD 180

Query: 165 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK 224
           YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
Sbjct: 181 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK 240

Query: 225 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP 284
           YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP
Sbjct: 241 YIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIP 300

Query: 285 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR 344
           TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR
Sbjct: 301 TLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR 360

Query: 345 KLVKARVITDLSSGI 359
           KLVKARVITDLSSGI
Sbjct: 361 KLVKARVITDLSSGI 375


>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
          Length = 390

 Score =  709 bits (1830), Expect = 0.0
 Identities = 358/390 (91%), Positives = 359/390 (92%), Gaps = 31/390 (7%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 39  ---------SKYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 89
                    S+YDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120

Query: 90  APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 149
           APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
Sbjct: 121 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 180

Query: 150 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 209
           GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
Sbjct: 181 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 240

Query: 210 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 269
           FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
Sbjct: 241 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 300

Query: 270 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 329
           GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
Sbjct: 301 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 360

Query: 330 ESWTHNIQREKEFLRKLVKARVITDLSSGI 359
           ESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 361 ESWTHNIQREKEFLRKLVKARVITDLSSGI 390


>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
          Length = 429

 Score =  684 bits (1765), Expect = 0.0
 Identities = 357/429 (83%), Positives = 358/429 (83%), Gaps = 70/429 (16%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED----------------SKYDRL 44
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                S+YDRL
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL 60

Query: 45  GFLLNLDSKL------------------PAE----------------------------- 57
           GFLLNLDSKL                  P E                             
Sbjct: 61  GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFL 120

Query: 58  -------LATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP 110
                  LATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
Sbjct: 121 KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP 180

Query: 111 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 170
           FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
Sbjct: 181 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 240

Query: 171 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 230
           LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
Sbjct: 241 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 300

Query: 231 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA 290
           RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
Sbjct: 301 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA 360

Query: 291 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR 350
           VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
Sbjct: 361 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR 420

Query: 351 VITDLSSGI 359
           VITDLSSGI
Sbjct: 421 VITDLSSGI 429


>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
          Length = 444

 Score =  678 bits (1750), Expect = 0.0
 Identities = 357/444 (80%), Positives = 358/444 (80%), Gaps = 85/444 (19%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 39  ---------SKYDRLGFLLNLDSKL------------------PAE-------------- 57
                    S+YDRLGFLLNLDSKL                  P E              
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120

Query: 58  ----------------------LATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 95
                                 LATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180

Query: 96  DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 155
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240

Query: 156 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 215
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300

Query: 216 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 275
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360

Query: 276 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 335
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420

Query: 336 IQREKEFLRKLVKARVITDLSSGI 359
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 421 IQREKEFLRKLVKARVITDLSSGI 444


>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
          Length = 413

 Score =  630 bits (1625), Expect = 0.0
 Identities = 339/419 (80%), Positives = 341/419 (81%), Gaps = 66/419 (15%)

Query: 1   MGLLVFVRNLLLALCLFLV------------------------LGFLYYSAWKLH----- 31
           MGLLVFVRNLLLALCLFLV                        LGFL     KL      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLSPRTLC 60

Query: 32  -----------------------------LLQWEEDSKYDRLGFLLNLDSKLP--AELAT 60
                                        L    ED+ +  LGFL     KLP  AELAT
Sbjct: 61  TVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAF-ALGFL-----KLPRPAELAT 114

Query: 61  KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI 120
           KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI
Sbjct: 115 KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLI 174

Query: 121 KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE 180
           KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE
Sbjct: 175 KAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFE 234

Query: 181 KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK 240
           KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK
Sbjct: 235 KDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWK 294

Query: 241 SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE 300
           SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE
Sbjct: 295 SVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDE 354

Query: 301 VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 359
           VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 355 VAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413


>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
          Length = 277

 Score =  461 bits (1187), Expect = e-130
 Identities = 232/249 (93%), Positives = 233/249 (93%), Gaps = 16/249 (6%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL 44
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS                +YDRL
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL 60

Query: 45  GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI 104
           GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
Sbjct: 61  GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI 120

Query: 105 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD 164
           REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD
Sbjct: 121 REFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDD 180

Query: 165 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK 224
           YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK
Sbjct: 181 YDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLK 240

Query: 225 YIVYKERVS 233
           YIVYKERVS
Sbjct: 241 YIVYKERVS 249



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 29/29 (100%), Positives = 29/29 (100%)

Query: 331 SWTHNIQREKEFLRKLVKARVITDLSSGI 359
           SWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 249 SWTHNIQREKEFLRKLVKARVITDLSSGI 277


>gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]
          Length = 139

 Score =  240 bits (613), Expect = 1e-63
 Identities = 116/116 (100%), Positives = 116/116 (100%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELAT 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELAT
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELAT 60

Query: 61  KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 116
           KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 61  KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 116


>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 2 [Homo sapiens]
          Length = 395

 Score =  231 bits (588), Expect = 1e-60
 Identities = 129/343 (37%), Positives = 200/343 (58%), Gaps = 7/343 (2%)

Query: 23  LYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELATKYAN-FSEGACKPGYASALMTA 81
           L +  W L++L+    ++   +  +  +D     + A KYA    +  C+P +A   M  
Sbjct: 50  LVFGVWILYILKLNYTTEECDMKKMHYVDPD-HVKRAQKYAQQVLQKECRPKFAKTSMAL 108

Query: 82  IFP-RFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLR 140
           +F  R+S     F+  + +      ++ PPFG +   + ++ +L +  E+ L   L +  
Sbjct: 109 LFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKT 168

Query: 141 CRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQR 200
           CRRC+++G+GG+L    LG  ++ +D+V+RLNSAPV+G+ + VG+KTT+R+TYPEGA   
Sbjct: 169 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLS 228

Query: 201 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS--ASDGFWKSVATRVPKEPPEIRILNP 258
             +Y  + LFV   FK  DF WL+ +V KE +       FWK VA ++P +P   RILNP
Sbjct: 229 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNP 288

Query: 259 YFIQEAAFTLIGLPF-NNGLMGRG-NIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 316
             I+E AF ++      +   GR  N+PT+G +AV +A H CDEV++AGFGYD++ P  P
Sbjct: 289 VIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTP 348

Query: 317 LHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 359
           LHY+++  MAA+     HN+  E +FL KLVK  V+ DLS GI
Sbjct: 349 LHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDLSGGI 391


>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 1 [Homo sapiens]
          Length = 418

 Score =  231 bits (588), Expect = 1e-60
 Identities = 129/343 (37%), Positives = 200/343 (58%), Gaps = 7/343 (2%)

Query: 23  LYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELATKYAN-FSEGACKPGYASALMTA 81
           L +  W L++L+    ++   +  +  +D     + A KYA    +  C+P +A   M  
Sbjct: 73  LVFGVWILYILKLNYTTEECDMKKMHYVDPD-HVKRAQKYAQQVLQKECRPKFAKTSMAL 131

Query: 82  IFP-RFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLR 140
           +F  R+S     F+  + +      ++ PPFG +   + ++ +L +  E+ L   L +  
Sbjct: 132 LFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKT 191

Query: 141 CRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQR 200
           CRRC+++G+GG+L    LG  ++ +D+V+RLNSAPV+G+ + VG+KTT+R+TYPEGA   
Sbjct: 192 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLS 251

Query: 201 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS--ASDGFWKSVATRVPKEPPEIRILNP 258
             +Y  + LFV   FK  DF WL+ +V KE +       FWK VA ++P +P   RILNP
Sbjct: 252 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNP 311

Query: 259 YFIQEAAFTLIGLPF-NNGLMGRG-NIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 316
             I+E AF ++      +   GR  N+PT+G +AV +A H CDEV++AGFGYD++ P  P
Sbjct: 312 VIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTP 371

Query: 317 LHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 359
           LHY+++  MAA+     HN+  E +FL KLVK  V+ DLS GI
Sbjct: 372 LHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDLSGGI 414


>gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]
          Length = 155

 Score =  228 bits (582), Expect = 5e-60
 Identities = 115/132 (87%), Positives = 116/132 (87%), Gaps = 16/132 (12%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS----------------KYDRL 44
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS                +YDRL
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL 60

Query: 45  GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI 104
           GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI
Sbjct: 61  GFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARI 120

Query: 105 REFVPPFGIKGQ 116
           REFVPPFGIKGQ
Sbjct: 121 REFVPPFGIKGQ 132


>gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]
          Length = 170

 Score =  223 bits (567), Expect = 3e-58
 Identities = 115/147 (78%), Positives = 116/147 (78%), Gaps = 31/147 (21%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 39  ---------SKYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 89
                    S+YDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120

Query: 90  APMFLDDSFRKWARIREFVPPFGIKGQ 116
           APMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 121 APMFLDDSFRKWARIREFVPPFGIKGQ 147


>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
           sapiens]
          Length = 329

 Score =  198 bits (504), Expect = 5e-51
 Identities = 112/291 (38%), Positives = 171/291 (58%), Gaps = 7/291 (2%)

Query: 70  CKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIRE-FVPPFGIKGQDNLIKAILSVTK 128
           C  G A +  + +F  +S+  P+FL      W +    +  P+G KG ++L+  +L++T 
Sbjct: 42  CLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITS 101

Query: 129 EYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTT 188
              +   + SLRCRRC++VGNG  L N SLG  I+ YD+V+RLN+APV G+E DVGSKTT
Sbjct: 102 S-SIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTT 160

Query: 189 LRITYPEGAMQRPE-QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 247
           +R+ YPE A   P+ +   D+L VL  FK  DF W++ I+  ++     GFWK       
Sbjct: 161 MRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETIL-SDKKRVRKGFWKQPPLIWD 219

Query: 248 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 307
             P +IRILNP+F++ AA  L+ LP       +   PT G +A+T+ALH CD V +AGFG
Sbjct: 220 VNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQK-PTTGLLAITLALHLCDLVHIAGFG 278

Query: 308 Y-DMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSS 357
           Y D       +HYYE + + ++  S  HN+ +E   ++++++   I +L+S
Sbjct: 279 YPDAYNKKQTIHYYEQITLKSMAGS-GHNVSQEALAIKRMLEMGAIKNLTS 328


>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
          Length = 331

 Score =  193 bits (491), Expect = 2e-49
 Identities = 111/346 (32%), Positives = 186/346 (53%), Gaps = 25/346 (7%)

Query: 14  LCLFLVLGFLYYSAWKLHLLQWEEDSKYDRLGFLLNLDSKLPAELATKYANFSEGACKPG 73
           + +FL   FLYY    LH + W             N+    P E+  +         KP 
Sbjct: 6   VAIFLSAVFLYYV---LHCILWGT-----------NVYWVAPVEMKRRN-KIQPCLSKPA 50

Query: 74  YASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVTKEY 130
           +AS L      RF +  P      FRK A +    +F  P+G++      +  LS  +  
Sbjct: 51  FASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSC 104

Query: 131 RLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR 190
            L    D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +TT R
Sbjct: 105 DLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFR 164

Query: 191 ITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEP 250
           + YPE     P   + ++  +L  FK  D +WL  ++  ++++ ++GFWK  A  +  +P
Sbjct: 165 LFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLIYKP 223

Query: 251 PEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDM 310
            +IRIL+P+ I+ AA+ L+  P       +   PT G +A+T+A + C EV +AGF Y+ 
Sbjct: 224 YQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNF 283

Query: 311 STPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 356
           S   +PLHYY    M+ + ++  HN+  E+ FL+ +++  ++ +L+
Sbjct: 284 SDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329


>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
           [Homo sapiens]
          Length = 340

 Score =  115 bits (289), Expect = 5e-26
 Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)

Query: 95  DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 152
           DD++R W R++    P  +   ++ IK +  V     + P L+  S+ CRRC +VGN G 
Sbjct: 95  DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150

Query: 153 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 212
           L   S G  ID +D V+R+N AP  GFE DVG+KTT  + YPE   +  +        +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206

Query: 213 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 272
             FK  D +W+   +    +S +   +  V  ++  +  +I I +P FI+          
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255

Query: 273 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 331
           F+N L G G  P+ G ++V  ++H CDEV + GFG D  +     HY+E    A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313

Query: 332 WTHNIQREKEFLRKLVKARVI 352
             H+   E      L     I
Sbjct: 314 GVHDADFESNVTATLASINKI 334


>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
           sapiens]
          Length = 340

 Score =  115 bits (289), Expect = 5e-26
 Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)

Query: 95  DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 152
           DD++R W R++    P  +   ++ IK +  V     + P L+  S+ CRRC +VGN G 
Sbjct: 95  DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150

Query: 153 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 212
           L   S G  ID +D V+R+N AP  GFE DVG+KTT  + YPE   +  +        +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206

Query: 213 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 272
             FK  D +W+   +    +S +   +  V  ++  +  +I I +P FI+          
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255

Query: 273 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 331
           F+N L G G  P+ G ++V  ++H CDEV + GFG D  +     HY+E    A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313

Query: 332 WTHNIQREKEFLRKLVKARVI 352
             H+   E      L     I
Sbjct: 314 GVHDADFESNVTATLASINKI 334


>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
           sapiens]
          Length = 350

 Score =  104 bits (260), Expect = 1e-22
 Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)

Query: 137 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 196
           D  +CRRC +VGN G L     G  +D ++ ++R+N AP  GFE+DVGS+TT    YPE 
Sbjct: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204

Query: 197 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 256
           A   P        FVL  FK  D  W+   +   ++  +    KS   RV KE  +++I 
Sbjct: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257

Query: 257 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 316
           NP F +           +      G  P+ G + +  ALH CDEV V GFG D S  N  
Sbjct: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308

Query: 317 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 352
            HY+E  R A   +++  H+   E   +  L KA  I
Sbjct: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344


>gi|21264332 sialyltransferase 7A [Homo sapiens]
          Length = 600

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)

Query: 92  MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 141
           +FLD       +W R+  F PPFG    + +L++ +++    V ++  L  +L   SLRC
Sbjct: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362

Query: 142 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 189
             C +VGNGG+L N  +G  ID +D V RL+ A +KG+E+DVG++T            +L
Sbjct: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422

Query: 190 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 245
            I    G    P   +   L  L G +  D++WL+ ++  + V + + FW       A R
Sbjct: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480

Query: 246 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 305
                    +L+P F++      +     +G   R   PT G++ +  AL  CD+V+  G
Sbjct: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540

Query: 306 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 346
           F   G++  +     HYY+T        SW        H+ + E+E  ++L
Sbjct: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579


>gi|192448440 sialyltransferase 7B [Homo sapiens]
          Length = 374

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)

Query: 101 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 154
           W R+ +   P+G +G  + + A    +L+ ++  +L  P  D+  +C RC +VGNGG+L 
Sbjct: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161

Query: 155 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 202
               G  ID +D V RLN A +KGFE+DVG+KT+             ++Y   G    P+
Sbjct: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221

Query: 203 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 258
             +   +F+ +  +  D+  L+  +    V   +G  K         P     + ++L+P
Sbjct: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277

Query: 259 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 318
            FI       +     N   G   +P+ G++ +  ALH CD+V+  GF    +      H
Sbjct: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336

Query: 319 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 352
           Y+E  +M  +     H++  E    R L KA ++
Sbjct: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369


>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)

Query: 131 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 185
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 186 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 242
           KTT+RI   +        +   SL+   +L  +    +     + YK+        +   
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397

Query: 243 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 302
             R P +P    IL+P FI +       +  N     + N P+ G + + + +  C EV 
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452

Query: 303 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 346
           V  + Y  S     L HY+E    AA      H +  EK  +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495


>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)

Query: 131 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 185
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 186 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 242
           KTT+RI   +        +   SL+   +L  +    +     + YK+        +   
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397

Query: 243 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 302
             R P +P    IL+P FI +       +  N     + N P+ G + + + +  C EV 
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452

Query: 303 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 346
           V  + Y  S     L HY+E    AA      H +  EK  +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495


>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform b [Homo sapiens]
          Length = 466

 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 131 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 185
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 186 KTTLRI 191
           KTT+RI
Sbjct: 338 KTTIRI 343


>gi|5174677 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 2 [Homo sapiens]
          Length = 375

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 58/242 (23%), Positives = 98/242 (40%), Gaps = 48/242 (19%)

Query: 130 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 186
           Y L P    L+ +    C IVGN GVL N   G  ID +  V+R N APV+ + +DVG K
Sbjct: 140 YELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLK 199

Query: 187 TTL----------------RITYPEGAMQRPEQYERDSLFV---LAGFKWQDFKWLKYIV 227
           T L                  T+ E  +QR        L++   +A    +  +W+  ++
Sbjct: 200 TDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELI 259

Query: 228 YKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLG 287
            K  V+    +            P +R+L+          + G    N +  +   PT G
Sbjct: 260 LKHHVNVRTAY------------PSLRLLH---------AVRGYWLTNKVHIKR--PTTG 296

Query: 288 SVAVTMALHGCDEVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR 344
            +  T+A   C ++ + G   F  D +      HYY++++     ++  H +  E + L+
Sbjct: 297 LLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALK 356

Query: 345 KL 346
            L
Sbjct: 357 SL 358


>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
          Length = 302

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 49/200 (24%), Positives = 82/200 (41%), Gaps = 30/200 (15%)

Query: 141 CRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQR 200
           CR C +V + G +    LG+ ID  + V R+N AP  GFE DVG ++TLR+         
Sbjct: 73  CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 132

Query: 201 PEQYE------RDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIR 254
              Y       RD+L+++    W   + +  ++         G       ++ +  P ++
Sbjct: 133 LRNYSHYFQKARDTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQ 180

Query: 255 ILNPYFIQEAAFTLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD- 309
           +   Y   E         F +         G+  + G   + +AL  C+E+ V G   D 
Sbjct: 181 V---YTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237

Query: 310 ----MSTPNAPLHYYETVRM 325
                S P+ P HY+E  R+
Sbjct: 238 YCREKSHPSVPYHYFEKGRL 257


>gi|13569938 sialyltransferase 7E [Homo sapiens]
          Length = 336

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)

Query: 139 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 198
           + CR C +V + G L +   GS+ID  + V+R+N AP +G+ +DVG++T+LR+     ++
Sbjct: 91  MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149

Query: 199 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 251
           QR  +   D L V  G     W    ++    K  VY      S    +  A  + +   
Sbjct: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207

Query: 252 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 306
           ++   +  F QE   T      +N  +      + G   +T+AL  CD + V G     F
Sbjct: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258

Query: 307 GYDMSTPNAPLHYYE 321
             D + P+ P HYYE
Sbjct: 259 CRDPNHPSVPYHYYE 273


>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 143 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 202
           RC +V + G L +  LG  IDD+D V+R N AP   F++DVG+KTT+R+   +  +   +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241

Query: 203 QYERDSLF 210
           ++ +DSL+
Sbjct: 242 RFLKDSLY 249


>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 143 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 202
           RC +V + G L +  LG  IDD+D V+R N AP   F++DVG+KTT+R+   +  +   +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241

Query: 203 QYERDSLF 210
           ++ +DSL+
Sbjct: 242 RFLKDSLY 249


>gi|5031999 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
          Length = 359

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 56/230 (24%), Positives = 94/230 (40%), Gaps = 24/230 (10%)

Query: 130 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 186
           + L P +  ++ RR   C +VGN G+L +   G  ID ++ V+R N APV  F  DVG+K
Sbjct: 125 HSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTK 184

Query: 187 TTLRITYPEGAMQRP-----EQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKS 241
           +   IT     +QR       + +R+              W+   +    V   +   + 
Sbjct: 185 SDF-ITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFM----VKGGEKHVEW 239

Query: 242 VATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNI--PTLGSVAVTMALHGCD 299
           V   + K   ++R   P      +  LI       L  +  I  P+ G +  T+A   CD
Sbjct: 240 VNALILKNKLKVRTAYP------SLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCD 293

Query: 300 EVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 346
           E+ + G   F  D++      HYY+ ++      +  H +  E + L  L
Sbjct: 294 EIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVL 343


>gi|110815855 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 3 [Homo sapiens]
          Length = 380

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)

Query: 121 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 176
           K + S++  +R L P +  +  +    C +VGN G+L     G  ID  D V R N AP 
Sbjct: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194

Query: 177 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 231
           + F++DVG KT L  T+    +++         +R++ F+          W+    +   
Sbjct: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253

Query: 232 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 282
            + +                  R L  +F++      + L +   +M   N         
Sbjct: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295

Query: 283 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 336
               + G +  T+A   C+E+ + G   FG+D +T  + P HYY+  +       W  + 
Sbjct: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354

Query: 337 QREKEF 342
           Q   EF
Sbjct: 355 QLPAEF 360


>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
          Length = 356

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)

Query: 139 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 197
           L  ++C +VGNGG+L     G +ID+ + V+R N  P+   + KDVGSK+ L    P   
Sbjct: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192

Query: 198 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 257
            QR +         +   K  +  ++    +  +                     +   N
Sbjct: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252

Query: 258 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 316
           P F++      IG  + +  +    + T G   V+ AL  C+EVA+ GF  + ++    P
Sbjct: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306

Query: 317 L--HYYETV 323
           +  HYY+ V
Sbjct: 307 ISHHYYDNV 315


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,751,140
Number of Sequences: 37866
Number of extensions: 599509
Number of successful extensions: 1102
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1025
Number of HSP's gapped (non-prelim): 60
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.