Search of human proteins with 28373070

Search of human proteins with 28373070

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
         (390 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]              786   0.0  
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]              755   0.0  
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]               744   0.0  
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]              709   0.0  
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]              681   0.0  
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]              676   0.0  
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]              491   e-139
gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]              299   3e-81
gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]              258   8e-69
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...   230   1e-60
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...   230   1e-60
gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]              223   3e-58
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H...   198   6e-51
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]               192   6e-49
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [...   115   5e-26
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H...   115   5e-26
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H...   104   1e-22
gi|21264332 sialyltransferase 7A [Homo sapiens]                        97   2e-20
gi|192448440 sialyltransferase 7B [Homo sapiens]                       80   3e-15
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    69   6e-12
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ...    69   6e-12
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    65   1e-10
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    64   2e-10
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]              60   4e-09
gi|13569938 sialyltransferase 7E [Homo sapiens]                        60   4e-09
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i...    59   7e-09
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ...    59   7e-09
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    58   1e-08
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran...    55   1e-07
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]                54   2e-07

>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
          Length = 390

 Score =  786 bits (2029), Expect = 0.0
 Identities = 390/390 (100%), Positives = 390/390 (100%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
           FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 180
           APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
Sbjct: 121 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 180

Query: 181 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 240
           GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
Sbjct: 181 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 240

Query: 241 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 300
           FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
Sbjct: 241 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 300

Query: 301 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 360
           GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
Sbjct: 301 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 360

Query: 361 ESWTHNIQREKEFLRKLVKARVITDLSSGI 390
           ESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 361 ESWTHNIQREKEFLRKLVKARVITDLSSGI 390


>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
          Length = 444

 Score =  755 bits (1949), Expect = 0.0
 Identities = 389/444 (87%), Positives = 389/444 (87%), Gaps = 54/444 (12%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKL------------------PAE-------------- 88
           FDSAGQTLGSEYDRLGFLLNLDSKL                  P E              
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120

Query: 89  ----------------------LATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 126
                                 LATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180

Query: 127 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 186
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240

Query: 187 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 246
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300

Query: 247 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 306
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360

Query: 307 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 366
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420

Query: 367 IQREKEFLRKLVKARVITDLSSGI 390
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 421 IQREKEFLRKLVKARVITDLSSGI 444


>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
          Length = 375

 Score =  744 bits (1921), Expect = 0.0
 Identities = 374/390 (95%), Positives = 375/390 (96%), Gaps = 15/390 (3%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS+               SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSN---------------SVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
           FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 105

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 180
           APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
Sbjct: 106 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 165

Query: 181 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 240
           GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
Sbjct: 166 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 225

Query: 241 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 300
           FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
Sbjct: 226 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 285

Query: 301 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 360
           GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
Sbjct: 286 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 345

Query: 361 ESWTHNIQREKEFLRKLVKARVITDLSSGI 390
           ESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 346 ESWTHNIQREKEFLRKLVKARVITDLSSGI 375


>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
          Length = 359

 Score =  709 bits (1830), Expect = 0.0
 Identities = 358/390 (91%), Positives = 359/390 (92%), Gaps = 31/390 (7%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
                    S+YDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 39  ---------SKYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 89

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 180
           APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
Sbjct: 90  APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 149

Query: 181 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 240
           GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
Sbjct: 150 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 209

Query: 241 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 300
           FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI
Sbjct: 210 FVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLI 269

Query: 301 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 360
           GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK
Sbjct: 270 GLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIK 329

Query: 361 ESWTHNIQREKEFLRKLVKARVITDLSSGI 390
           ESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 330 ESWTHNIQREKEFLRKLVKARVITDLSSGI 359


>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
          Length = 413

 Score =  681 bits (1757), Expect = 0.0
 Identities = 357/414 (86%), Positives = 361/414 (87%), Gaps = 25/414 (6%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYS------HSSSPQEKPVA 54
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS KY       +  S       
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS-KYDRLGFLLNLDSKLSPRTL 59

Query: 55  DSVVLSFD----SAGQT-------------LGSEYDRLGFLLN-LDSKLPAELATKYANF 96
            +VV   D    S G+              L S  +   F L  L    PAELATKYANF
Sbjct: 60  CTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFLKLPRPAELATKYANF 119

Query: 97  SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILS 156
           SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILS
Sbjct: 120 SEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILS 179

Query: 157 VTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216
           VTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS
Sbjct: 180 VTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239

Query: 217 KTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATR 276
           KTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATR
Sbjct: 240 KTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATR 299

Query: 277 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 336
           VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG
Sbjct: 300 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 359

Query: 337 FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 390
           FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 360 FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI 413


>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
          Length = 429

 Score =  676 bits (1743), Expect = 0.0
 Identities = 355/429 (82%), Positives = 361/429 (84%), Gaps = 39/429 (9%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVAD----- 55
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS+    S     + +       
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRL 60

Query: 56  ----------------SVVLSFD----SAGQT-------------LGSEYDRLGFLLN-L 81
                           +VV   D    S G+              L S  +   F L  L
Sbjct: 61  GFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDAAFALGFL 120

Query: 82  DSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP 141
               PAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP
Sbjct: 121 KLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPP 180

Query: 142 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 201
           FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR
Sbjct: 181 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 240

Query: 202 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 261
           LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE
Sbjct: 241 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 300

Query: 262 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA 321
           RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA
Sbjct: 301 RVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVA 360

Query: 322 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR 381
           VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR
Sbjct: 361 VTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKAR 420

Query: 382 VITDLSSGI 390
           VITDLSSGI
Sbjct: 421 VITDLSSGI 429


>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
          Length = 277

 Score =  491 bits (1263), Expect = e-139
 Identities = 248/264 (93%), Positives = 249/264 (94%), Gaps = 15/264 (5%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS+               SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSN---------------SVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
           FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 105

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 180
           APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN
Sbjct: 106 APMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGN 165

Query: 181 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 240
           GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL
Sbjct: 166 GGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSL 225

Query: 241 FVLAGFKWQDFKWLKYIVYKERVS 264
           FVLAGFKWQDFKWLKYIVYKERVS
Sbjct: 226 FVLAGFKWQDFKWLKYIVYKERVS 249



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 29/29 (100%), Positives = 29/29 (100%)

Query: 362 SWTHNIQREKEFLRKLVKARVITDLSSGI 390
           SWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 249 SWTHNIQREKEFLRKLVKARVITDLSSGI 277


>gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]
          Length = 170

 Score =  299 bits (766), Expect = 3e-81
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
           FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQ 147
           APMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 121 APMFLDDSFRKWARIREFVPPFGIKGQ 147


>gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]
          Length = 155

 Score =  258 bits (658), Expect = 8e-69
 Identities = 131/147 (89%), Positives = 132/147 (89%), Gaps = 15/147 (10%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS+               SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSN---------------SVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
           FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 105

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQ 147
           APMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 106 APMFLDDSFRKWARIREFVPPFGIKGQ 132


>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 2 [Homo sapiens]
          Length = 395

 Score =  230 bits (587), Expect = 1e-60
 Identities = 124/307 (40%), Positives = 185/307 (60%), Gaps = 6/307 (1%)

Query: 90  ATKYAN-FSEGACKPGYASALMTAIFP-RFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 147
           A KYA    +  C+P +A   M  +F  R+S     F+  + +      ++ PPFG +  
Sbjct: 85  AQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKF 144

Query: 148 DNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 207
            + ++ +L +  E+ L   L +  CRRC+++G+GG+L    LG  ++ +D+V+RLNSAPV
Sbjct: 145 SSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPV 204

Query: 208 KGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS--A 265
           +G+ + VG+KTT+R+TYPEGA     +Y  + LFV   FK  DF WL+ +V KE +    
Sbjct: 205 EGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWV 264

Query: 266 SDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPF-NNGLMGRG-NIPTLGSVAVT 323
              FWK VA ++P +P   RILNP  I+E AF ++      +   GR  N+PT+G +AV 
Sbjct: 265 RLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVV 324

Query: 324 MALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 383
           +A H CDEV++AGFGYD++ P  PLHY+++  MAA+     HN+  E +FL KLVK  V+
Sbjct: 325 LATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVV 384

Query: 384 TDLSSGI 390
            DLS GI
Sbjct: 385 KDLSGGI 391


>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 1 [Homo sapiens]
          Length = 418

 Score =  230 bits (587), Expect = 1e-60
 Identities = 124/307 (40%), Positives = 185/307 (60%), Gaps = 6/307 (1%)

Query: 90  ATKYAN-FSEGACKPGYASALMTAIFP-RFSKPAPMFLDDSFRKWARIREFVPPFGIKGQ 147
           A KYA    +  C+P +A   M  +F  R+S     F+  + +      ++ PPFG +  
Sbjct: 108 AQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKF 167

Query: 148 DNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 207
            + ++ +L +  E+ L   L +  CRRC+++G+GG+L    LG  ++ +D+V+RLNSAPV
Sbjct: 168 SSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPV 227

Query: 208 KGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVS--A 265
           +G+ + VG+KTT+R+TYPEGA     +Y  + LFV   FK  DF WL+ +V KE +    
Sbjct: 228 EGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWV 287

Query: 266 SDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPF-NNGLMGRG-NIPTLGSVAVT 323
              FWK VA ++P +P   RILNP  I+E AF ++      +   GR  N+PT+G +AV 
Sbjct: 288 RLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVV 347

Query: 324 MALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 383
           +A H CDEV++AGFGYD++ P  PLHY+++  MAA+     HN+  E +FL KLVK  V+
Sbjct: 348 LATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVV 407

Query: 384 TDLSSGI 390
            DLS GI
Sbjct: 408 KDLSGGI 414


>gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]
          Length = 139

 Score =  223 bits (567), Expect = 3e-58
 Identities = 115/147 (78%), Positives = 116/147 (78%), Gaps = 31/147 (21%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 120
                    S+YDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP
Sbjct: 39  ---------SKYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKP 89

Query: 121 APMFLDDSFRKWARIREFVPPFGIKGQ 147
           APMFLDDSFRKWARIREFVPPFGIKGQ
Sbjct: 90  APMFLDDSFRKWARIREFVPPFGIKGQ 116


>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
           sapiens]
          Length = 329

 Score =  198 bits (504), Expect = 6e-51
 Identities = 112/291 (38%), Positives = 171/291 (58%), Gaps = 7/291 (2%)

Query: 101 CKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIRE-FVPPFGIKGQDNLIKAILSVTK 159
           C  G A +  + +F  +S+  P+FL      W +    +  P+G KG ++L+  +L++T 
Sbjct: 42  CLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITS 101

Query: 160 EYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTT 219
              +   + SLRCRRC++VGNG  L N SLG  I+ YD+V+RLN+APV G+E DVGSKTT
Sbjct: 102 S-SIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTT 160

Query: 220 LRITYPEGAMQRPE-QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 278
           +R+ YPE A   P+ +   D+L VL  FK  DF W++ I+  ++     GFWK       
Sbjct: 161 MRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETIL-SDKKRVRKGFWKQPPLIWD 219

Query: 279 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 338
             P +IRILNP+F++ AA  L+ LP       +   PT G +A+T+ALH CD V +AGFG
Sbjct: 220 VNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQK-PTTGLLAITLALHLCDLVHIAGFG 278

Query: 339 Y-DMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSS 388
           Y D       +HYYE + + ++  S  HN+ +E   ++++++   I +L+S
Sbjct: 279 YPDAYNKKQTIHYYEQITLKSMAGS-GHNVSQEALAIKRMLEMGAIKNLTS 328


>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
          Length = 331

 Score =  192 bits (487), Expect = 6e-49
 Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)

Query: 102 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 158
           KP +AS L      RF +  P      FRK A +    +F  P+G++      +  LS  
Sbjct: 48  KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101

Query: 159 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 218
           +   L    D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161

Query: 219 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 278
           T R+ YPE     P   + ++  +L  FK  D +WL  ++  ++++ ++GFWK  A  + 
Sbjct: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220

Query: 279 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 338
            +P +IRIL+P+ I+ AA+ L+  P       +   PT G +A+T+A + C EV +AGF 
Sbjct: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280

Query: 339 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 387
           Y+ S   +PLHYY    M+ + ++  HN+  E+ FL+ +++  ++ +L+
Sbjct: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329


>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
           [Homo sapiens]
          Length = 340

 Score =  115 bits (289), Expect = 5e-26
 Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)

Query: 126 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 183
           DD++R W R++    P  +   ++ IK +  V     + P L+  S+ CRRC +VGN G 
Sbjct: 95  DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150

Query: 184 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 243
           L   S G  ID +D V+R+N AP  GFE DVG+KTT  + YPE   +  +        +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206

Query: 244 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 303
             FK  D +W+   +    +S +   +  V  ++  +  +I I +P FI+          
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255

Query: 304 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 362
           F+N L G G  P+ G ++V  ++H CDEV + GFG D  +     HY+E    A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313

Query: 363 WTHNIQREKEFLRKLVKARVI 383
             H+   E      L     I
Sbjct: 314 GVHDADFESNVTATLASINKI 334


>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
           sapiens]
          Length = 340

 Score =  115 bits (289), Expect = 5e-26
 Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)

Query: 126 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 183
           DD++R W R++    P  +   ++ IK +  V     + P L+  S+ CRRC +VGN G 
Sbjct: 95  DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150

Query: 184 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 243
           L   S G  ID +D V+R+N AP  GFE DVG+KTT  + YPE   +  +        +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206

Query: 244 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 303
             FK  D +W+   +    +S +   +  V  ++  +  +I I +P FI+          
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255

Query: 304 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 362
           F+N L G G  P+ G ++V  ++H CDEV + GFG D  +     HY+E    A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313

Query: 363 WTHNIQREKEFLRKLVKARVI 383
             H+   E      L     I
Sbjct: 314 GVHDADFESNVTATLASINKI 334


>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
           sapiens]
          Length = 350

 Score =  104 bits (260), Expect = 1e-22
 Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)

Query: 168 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 227
           D  +CRRC +VGN G L     G  +D ++ ++R+N AP  GFE+DVGS+TT    YPE 
Sbjct: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204

Query: 228 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 287
           A   P        FVL  FK  D  W+   +   ++  +    KS   RV KE  +++I 
Sbjct: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257

Query: 288 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 347
           NP F +           +      G  P+ G + +  ALH CDEV V GFG D S  N  
Sbjct: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308

Query: 348 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 383
            HY+E  R A   +++  H+   E   +  L KA  I
Sbjct: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344


>gi|21264332 sialyltransferase 7A [Homo sapiens]
          Length = 600

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)

Query: 123 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 172
           +FLD       +W R+  F PPFG    + +L++ +++    V ++  L  +L   SLRC
Sbjct: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362

Query: 173 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 220
             C +VGNGG+L N  +G  ID +D V RL+ A +KG+E+DVG++T            +L
Sbjct: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422

Query: 221 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 276
            I    G    P   +   L  L G +  D++WL+ ++  + V + + FW       A R
Sbjct: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480

Query: 277 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 336
                    +L+P F++      +     +G   R   PT G++ +  AL  CD+V+  G
Sbjct: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540

Query: 337 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 377
           F   G++  +     HYY+T        SW        H+ + E+E  ++L
Sbjct: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579


>gi|192448440 sialyltransferase 7B [Homo sapiens]
          Length = 374

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)

Query: 132 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 185
           W R+ +   P+G +G  + + A    +L+ ++  +L  P  D+  +C RC +VGNGG+L 
Sbjct: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161

Query: 186 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 233
               G  ID +D V RLN A +KGFE+DVG+KT+             ++Y   G    P+
Sbjct: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221

Query: 234 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 289
             +   +F+ +  +  D+  L+  +    V   +G  K         P     + ++L+P
Sbjct: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277

Query: 290 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 349
            FI       +     N   G   +P+ G++ +  ALH CD+V+  GF    +      H
Sbjct: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336

Query: 350 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 383
           Y+E  +M  +     H++  E    R L KA ++
Sbjct: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369


>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)

Query: 162 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 217 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 273
           KTT+RI   +        +   SL+   +L  +    +     + YK+        +   
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397

Query: 274 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 333
             R P +P    IL+P FI +       +  N     + N P+ G + + + +  C EV 
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452

Query: 334 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 377
           V  + Y  S     L HY+E    AA      H +  EK  +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495


>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)

Query: 162 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 217 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 273
           KTT+RI   +        +   SL+   +L  +    +     + YK+        +   
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397

Query: 274 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 333
             R P +P    IL+P FI +       +  N     + N P+ G + + + +  C EV 
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452

Query: 334 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 377
           V  + Y  S     L HY+E    AA      H +  EK  +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495


>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform b [Homo sapiens]
          Length = 466

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 162 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 217 KTTLRI 222
           KTT+RI
Sbjct: 338 KTTIRI 343


>gi|5174677 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 2 [Homo sapiens]
          Length = 375

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 58/242 (23%), Positives = 98/242 (40%), Gaps = 48/242 (19%)

Query: 161 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 217
           Y L P    L+ +    C IVGN GVL N   G  ID +  V+R N APV+ + +DVG K
Sbjct: 140 YELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLK 199

Query: 218 TTL----------------RITYPEGAMQRPEQYERDSLFV---LAGFKWQDFKWLKYIV 258
           T L                  T+ E  +QR        L++   +A    +  +W+  ++
Sbjct: 200 TDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELI 259

Query: 259 YKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLG 318
            K  V+    +            P +R+L+          + G    N +  +   PT G
Sbjct: 260 LKHHVNVRTAY------------PSLRLLH---------AVRGYWLTNKVHIKR--PTTG 296

Query: 319 SVAVTMALHGCDEVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR 375
            +  T+A   C ++ + G   F  D +      HYY++++     ++  H +  E + L+
Sbjct: 297 LLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALK 356

Query: 376 KL 377
            L
Sbjct: 357 SL 358


>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
          Length = 302

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 49/200 (24%), Positives = 82/200 (41%), Gaps = 30/200 (15%)

Query: 172 CRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQR 231
           CR C +V + G +    LG+ ID  + V R+N AP  GFE DVG ++TLR+         
Sbjct: 73  CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 132

Query: 232 PEQYE------RDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIR 285
              Y       RD+L+++    W   + +  ++         G       ++ +  P ++
Sbjct: 133 LRNYSHYFQKARDTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQ 180

Query: 286 ILNPYFIQEAAFTLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD- 340
           +   Y   E         F +         G+  + G   + +AL  C+E+ V G   D 
Sbjct: 181 V---YTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237

Query: 341 ----MSTPNAPLHYYETVRM 356
                S P+ P HY+E  R+
Sbjct: 238 YCREKSHPSVPYHYFEKGRL 257


>gi|13569938 sialyltransferase 7E [Homo sapiens]
          Length = 336

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)

Query: 170 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 229
           + CR C +V + G L +   GS+ID  + V+R+N AP +G+ +DVG++T+LR+     ++
Sbjct: 91  MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149

Query: 230 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 282
           QR  +   D L V  G     W    ++    K  VY      S    +  A  + +   
Sbjct: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207

Query: 283 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 337
           ++   +  F QE   T      +N  +      + G   +T+AL  CD + V G     F
Sbjct: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258

Query: 338 GYDMSTPNAPLHYYE 352
             D + P+ P HYYE
Sbjct: 259 CRDPNHPSVPYHYYE 273


>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 174 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 233
           RC +V + G L +  LG  IDD+D V+R N AP   F++DVG+KTT+R+   +  +   +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241

Query: 234 QYERDSLF 241
           ++ +DSL+
Sbjct: 242 RFLKDSLY 249


>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 174 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 233
           RC +V + G L +  LG  IDD+D V+R N AP   F++DVG+KTT+R+   +  +   +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241

Query: 234 QYERDSLF 241
           ++ +DSL+
Sbjct: 242 RFLKDSLY 249


>gi|5031999 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
          Length = 359

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 56/230 (24%), Positives = 94/230 (40%), Gaps = 24/230 (10%)

Query: 161 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 217
           + L P +  ++ RR   C +VGN G+L +   G  ID ++ V+R N APV  F  DVG+K
Sbjct: 125 HSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTK 184

Query: 218 TTLRITYPEGAMQRP-----EQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKS 272
           +   IT     +QR       + +R+              W+   +    V   +   + 
Sbjct: 185 SDF-ITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFM----VKGGEKHVEW 239

Query: 273 VATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNI--PTLGSVAVTMALHGCD 330
           V   + K   ++R   P      +  LI       L  +  I  P+ G +  T+A   CD
Sbjct: 240 VNALILKNKLKVRTAYP------SLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCD 293

Query: 331 EVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 377
           E+ + G   F  D++      HYY+ ++      +  H +  E + L  L
Sbjct: 294 EIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVL 343


>gi|110815855 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 3 [Homo sapiens]
          Length = 380

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)

Query: 152 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 207
           K + S++  +R L P +  +  +    C +VGN G+L     G  ID  D V R N AP 
Sbjct: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194

Query: 208 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 262
           + F++DVG KT L  T+    +++         +R++ F+          W+    +   
Sbjct: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253

Query: 263 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 313
            + +                  R L  +F++      + L +   +M   N         
Sbjct: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295

Query: 314 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 367
               + G +  T+A   C+E+ + G   FG+D +T  + P HYY+  +       W  + 
Sbjct: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354

Query: 368 QREKEF 373
           Q   EF
Sbjct: 355 QLPAEF 360


>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
          Length = 356

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)

Query: 170 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 228
           L  ++C +VGNGG+L     G +ID+ + V+R N  P+   + KDVGSK+ L    P   
Sbjct: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192

Query: 229 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 288
            QR +         +   K  +  ++    +  +                     +   N
Sbjct: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252

Query: 289 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 347
           P F++      IG  + +  +    + T G   V+ AL  C+EVA+ GF  + ++    P
Sbjct: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306

Query: 348 L--HYYETV 354
           +  HYY+ V
Sbjct: 307 ISHHYYDNV 315


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,981,408
Number of Sequences: 37866
Number of extensions: 658440
Number of successful extensions: 1297
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1219
Number of HSP's gapped (non-prelim): 58
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.