Guide to the Human Genome
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Search of human proteins with 28373068

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
         (444 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]              892   0.0  
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]              851   0.0  
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]              816   0.0  
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]              751   0.0  
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]               709   0.0  
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]              674   0.0  
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]              456   e-128
gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]              264   1e-70
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...   231   1e-60
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...   231   1e-60
gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]              223   4e-58
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H...   198   7e-51
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]               192   7e-49
gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]              187   1e-47
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [...   115   6e-26
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H...   115   6e-26
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H...   104   1e-22
gi|21264332 sialyltransferase 7A [Homo sapiens]                        97   3e-20
gi|192448440 sialyltransferase 7B [Homo sapiens]                       80   4e-15
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    69   7e-12
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ...    69   7e-12
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    65   1e-10
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    64   3e-10
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]              60   5e-09
gi|13569938 sialyltransferase 7E [Homo sapiens]                        60   5e-09
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i...    59   9e-09
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ...    59   9e-09
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    58   2e-08
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran...    55   2e-07
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]                54   3e-07

>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
          Length = 444

 Score =  892 bits (2306), Expect = 0.0
 Identities = 444/444 (100%), Positives = 444/444 (100%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
           LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300

Query: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360

Query: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420

Query: 421 IQREKEFLRKLVKARVITDLSSGI 444
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 421 IQREKEFLRKLVKARVITDLSSGI 444


>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
          Length = 429

 Score =  851 bits (2198), Expect = 0.0
 Identities = 428/444 (96%), Positives = 429/444 (96%), Gaps = 15/444 (3%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS+               SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSN---------------SVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 105

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
           LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 106 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 165

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 166 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 225

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 226 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 285

Query: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 286 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 345

Query: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 346 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 405

Query: 421 IQREKEFLRKLVKARVITDLSSGI 444
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 406 IQREKEFLRKLVKARVITDLSSGI 429


>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
          Length = 413

 Score =  816 bits (2107), Expect = 0.0
 Identities = 412/444 (92%), Positives = 413/444 (93%), Gaps = 31/444 (6%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS                     
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS--------------------- 39

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
                     +YDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI
Sbjct: 40  ----------KYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 89

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
           LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 90  LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 149

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 150 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 209

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 210 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 269

Query: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 270 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 329

Query: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 330 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 389

Query: 421 IQREKEFLRKLVKARVITDLSSGI 444
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 390 IQREKEFLRKLVKARVITDLSSGI 413


>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
          Length = 390

 Score =  751 bits (1938), Expect = 0.0
 Identities = 387/444 (87%), Positives = 387/444 (87%), Gaps = 54/444 (12%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKL P  L T                            
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKL-PAELAT---------------------------- 91

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 92  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 126

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 127 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 186

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 187 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 246

Query: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 247 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 306

Query: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 307 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 366

Query: 421 IQREKEFLRKLVKARVITDLSSGI 444
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 367 IQREKEFLRKLVKARVITDLSSGI 390


>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
          Length = 375

 Score =  709 bits (1830), Expect = 0.0
 Identities = 371/444 (83%), Positives = 372/444 (83%), Gaps = 69/444 (15%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS               +SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS---------------NSVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKL P  L T                            
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKL-PAELAT---------------------------- 76

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 77  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 111

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 112 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 171

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 172 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 231

Query: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 232 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 291

Query: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 292 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 351

Query: 421 IQREKEFLRKLVKARVITDLSSGI 444
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 352 IQREKEFLRKLVKARVITDLSSGI 375


>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
          Length = 359

 Score =  674 bits (1739), Expect = 0.0
 Identities = 355/444 (79%), Positives = 356/444 (80%), Gaps = 85/444 (19%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
                    S+YDRLGFLLNLDSKL P  L T                            
Sbjct: 39  ---------SKYDRLGFLLNLDSKL-PAELAT---------------------------- 60

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 61  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 95

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 96  DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 155

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 156 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 215

Query: 301 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 360
           KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN
Sbjct: 216 KWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNN 275

Query: 361 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 420
           GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN
Sbjct: 276 GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHN 335

Query: 421 IQREKEFLRKLVKARVITDLSSGI 444
           IQREKEFLRKLVKARVITDLSSGI
Sbjct: 336 IQREKEFLRKLVKARVITDLSSGI 359


>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
          Length = 277

 Score =  456 bits (1172), Expect = e-128
 Identities = 245/318 (77%), Positives = 246/318 (77%), Gaps = 69/318 (21%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS               +SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS---------------NSVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKL P  L T                            
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKL-PAELAT---------------------------- 76

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 77  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 111

Query: 181 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 240
           DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN
Sbjct: 112 DSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLAN 171

Query: 241 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 300
           KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF
Sbjct: 172 KSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGF 231

Query: 301 KWQDFKWLKYIVYKERVS 318
           KWQDFKWLKYIVYKERVS
Sbjct: 232 KWQDFKWLKYIVYKERVS 249



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 29/29 (100%), Positives = 29/29 (100%)

Query: 416 SWTHNIQREKEFLRKLVKARVITDLSSGI 444
           SWTHNIQREKEFLRKLVKARVITDLSSGI
Sbjct: 249 SWTHNIQREKEFLRKLVKARVITDLSSGI 277


>gi|28373072 sialyltransferase 6 isoform c [Homo sapiens]
          Length = 170

 Score =  264 bits (675), Expect = 1e-70
 Identities = 144/201 (71%), Positives = 144/201 (71%), Gaps = 54/201 (26%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKL P  L T                            
Sbjct: 61  FDSAGQTLGSEYDRLGFLLNLDSKL-PAELAT---------------------------- 91

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 92  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 126

Query: 181 DSFRKWARIREFVPPFGIKGQ 201
           DSFRKWARIREFVPPFGIKGQ
Sbjct: 127 DSFRKWARIREFVPPFGIKGQ 147


>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 2 [Homo sapiens]
          Length = 395

 Score =  231 bits (589), Expect = 1e-60
 Identities = 125/313 (39%), Positives = 187/313 (59%), Gaps = 6/313 (1%)

Query: 138 PRPAELATKYAN-FSEGACKPGYASALMTAIFP-RFSKPAPMFLDDSFRKWARIREFVPP 195
           P   + A KYA    +  C+P +A   M  +F  R+S     F+  + +      ++ PP
Sbjct: 79  PDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPP 138

Query: 196 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 255
           FG +   + ++ +L +  E+ L   L +  CRRC+++G+GG+L    LG  ++ +D+V+R
Sbjct: 139 FGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIR 198

Query: 256 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 315
           LNSAPV+G+ + VG+KTT+R+TYPEGA     +Y  + LFV   FK  DF WL+ +V KE
Sbjct: 199 LNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKE 258

Query: 316 RVS--ASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPF-NNGLMGRG-NIPTL 371
            +       FWK VA ++P +P   RILNP  I+E AF ++      +   GR  N+PT+
Sbjct: 259 TLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTI 318

Query: 372 GSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 431
           G +AV +A H CDEV++AGFGYD++ P  PLHY+++  MAA+     HN+  E +FL KL
Sbjct: 319 GVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKL 378

Query: 432 VKARVITDLSSGI 444
           VK  V+ DLS GI
Sbjct: 379 VKEGVVKDLSGGI 391


>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 1 [Homo sapiens]
          Length = 418

 Score =  231 bits (589), Expect = 1e-60
 Identities = 125/313 (39%), Positives = 187/313 (59%), Gaps = 6/313 (1%)

Query: 138 PRPAELATKYAN-FSEGACKPGYASALMTAIFP-RFSKPAPMFLDDSFRKWARIREFVPP 195
           P   + A KYA    +  C+P +A   M  +F  R+S     F+  + +      ++ PP
Sbjct: 102 PDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPP 161

Query: 196 FGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVR 255
           FG +   + ++ +L +  E+ L   L +  CRRC+++G+GG+L    LG  ++ +D+V+R
Sbjct: 162 FGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIR 221

Query: 256 LNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKE 315
           LNSAPV+G+ + VG+KTT+R+TYPEGA     +Y  + LFV   FK  DF WL+ +V KE
Sbjct: 222 LNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKE 281

Query: 316 RVS--ASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPF-NNGLMGRG-NIPTL 371
            +       FWK VA ++P +P   RILNP  I+E AF ++      +   GR  N+PT+
Sbjct: 282 TLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTI 341

Query: 372 GSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 431
           G +AV +A H CDEV++AGFGYD++ P  PLHY+++  MAA+     HN+  E +FL KL
Sbjct: 342 GVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKL 401

Query: 432 VKARVITDLSSGI 444
           VK  V+ DLS GI
Sbjct: 402 VKEGVVKDLSGGI 414


>gi|28373076 sialyltransferase 6 isoform e [Homo sapiens]
          Length = 155

 Score =  223 bits (567), Expect = 4e-58
 Identities = 128/201 (63%), Positives = 129/201 (64%), Gaps = 69/201 (34%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS               +SVVLS
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDS---------------NSVVLS 45

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
           FDSAGQTLGSEYDRLGFLLNLDSKL P  L T                            
Sbjct: 46  FDSAGQTLGSEYDRLGFLLNLDSKL-PAELAT---------------------------- 76

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 77  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 111

Query: 181 DSFRKWARIREFVPPFGIKGQ 201
           DSFRKWARIREFVPPFGIKGQ
Sbjct: 112 DSFRKWARIREFVPPFGIKGQ 132


>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
           sapiens]
          Length = 329

 Score =  198 bits (504), Expect = 7e-51
 Identities = 112/291 (38%), Positives = 171/291 (58%), Gaps = 7/291 (2%)

Query: 155 CKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIRE-FVPPFGIKGQDNLIKAILSVTK 213
           C  G A +  + +F  +S+  P+FL      W +    +  P+G KG ++L+  +L++T 
Sbjct: 42  CLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITS 101

Query: 214 EYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTT 273
              +   + SLRCRRC++VGNG  L N SLG  I+ YD+V+RLN+APV G+E DVGSKTT
Sbjct: 102 S-SIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTT 160

Query: 274 LRITYPEGAMQRPE-QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 332
           +R+ YPE A   P+ +   D+L VL  FK  DF W++ I+  ++     GFWK       
Sbjct: 161 MRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETIL-SDKKRVRKGFWKQPPLIWD 219

Query: 333 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 392
             P +IRILNP+F++ AA  L+ LP       +   PT G +A+T+ALH CD V +AGFG
Sbjct: 220 VNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQK-PTTGLLAITLALHLCDLVHIAGFG 278

Query: 393 Y-DMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSS 442
           Y D       +HYYE + + ++  S  HN+ +E   ++++++   I +L+S
Sbjct: 279 YPDAYNKKQTIHYYEQITLKSMAGS-GHNVSQEALAIKRMLEMGAIKNLTS 328


>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
          Length = 331

 Score =  192 bits (487), Expect = 7e-49
 Identities = 99/289 (34%), Positives = 168/289 (58%), Gaps = 10/289 (3%)

Query: 156 KPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIR---EFVPPFGIKGQDNLIKAILSVT 212
           KP +AS L      RF +  P      FRK A +    +F  P+G++      +  LS  
Sbjct: 48  KPAFASLL------RFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKL 101

Query: 213 KEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT 272
           +   L    D++ C++C++VGNGGVL NK+LG +ID YD+++R+N+ PV G E++VG +T
Sbjct: 102 QSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRT 161

Query: 273 TLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVP 332
           T R+ YPE     P   + ++  +L  FK  D +WL  ++  ++++ ++GFWK  A  + 
Sbjct: 162 TFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKIN-TNGFWKKPALNLI 220

Query: 333 KEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFG 392
            +P +IRIL+P+ I+ AA+ L+  P       +   PT G +A+T+A + C EV +AGF 
Sbjct: 221 YKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFK 280

Query: 393 YDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLS 441
           Y+ S   +PLHYY    M+ + ++  HN+  E+ FL+ +++  ++ +L+
Sbjct: 281 YNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLT 329


>gi|28373084 sialyltransferase 6 isoform h [Homo sapiens]
          Length = 139

 Score =  187 bits (476), Expect = 1e-47
 Identities = 112/201 (55%), Positives = 113/201 (56%), Gaps = 85/201 (42%)

Query: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSSKYSHSSSPQEKPVADSVVLS 60
           MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED                      
Sbjct: 1   MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEED---------------------- 38

Query: 61  FDSAGQTLGSEYDRLGFLLNLDSKLSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEI 120
                    S+YDRLGFLLNLDSKL P  L T                            
Sbjct: 39  ---------SKYDRLGFLLNLDSKL-PAELAT---------------------------- 60

Query: 121 LKSLSEDAAFALGFLKLPRPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 180
                                    KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD
Sbjct: 61  -------------------------KYANFSEGACKPGYASALMTAIFPRFSKPAPMFLD 95

Query: 181 DSFRKWARIREFVPPFGIKGQ 201
           DSFRKWARIREFVPPFGIKGQ
Sbjct: 96  DSFRKWARIREFVPPFGIKGQ 116


>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
           [Homo sapiens]
          Length = 340

 Score =  115 bits (289), Expect = 6e-26
 Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)

Query: 180 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 237
           DD++R W R++    P  +   ++ IK +  V     + P L+  S+ CRRC +VGN G 
Sbjct: 95  DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150

Query: 238 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 297
           L   S G  ID +D V+R+N AP  GFE DVG+KTT  + YPE   +  +        +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206

Query: 298 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 357
             FK  D +W+   +    +S +   +  V  ++  +  +I I +P FI+          
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255

Query: 358 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 416
           F+N L G G  P+ G ++V  ++H CDEV + GFG D  +     HY+E    A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313

Query: 417 WTHNIQREKEFLRKLVKARVI 437
             H+   E      L     I
Sbjct: 314 GVHDADFESNVTATLASINKI 334


>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
           sapiens]
          Length = 340

 Score =  115 bits (289), Expect = 6e-26
 Identities = 81/261 (31%), Positives = 126/261 (48%), Gaps = 24/261 (9%)

Query: 180 DDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALD--SLRCRRCIIVGNGGV 237
           DD++R W R++    P  +   ++ IK +  V     + P L+  S+ CRRC +VGN G 
Sbjct: 95  DDTYRWWLRLQREKKPNNL---NDTIKELFRVVPG-NVDPMLEKRSVGCRRCAVVGNSGN 150

Query: 238 LANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVL 297
           L   S G  ID +D V+R+N AP  GFE DVG+KTT  + YPE   +  +        +L
Sbjct: 151 LRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVS----MIL 206

Query: 298 AGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLP 357
             FK  D +W+   +    +S +   +  V  ++  +  +I I +P FI+          
Sbjct: 207 VPFKTIDLEWVVSAITTGTISHT---YIPVPAKIRVKQDKILIYHPAFIKYV-------- 255

Query: 358 FNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMA-AIKES 416
           F+N L G G  P+ G ++V  ++H CDEV + GFG D  +     HY+E    A A +++
Sbjct: 256 FDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGAD--SKGNWHHYWENNPSAGAFRKT 313

Query: 417 WTHNIQREKEFLRKLVKARVI 437
             H+   E      L     I
Sbjct: 314 GVHDADFESNVTATLASINKI 334


>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
           sapiens]
          Length = 350

 Score =  104 bits (260), Expect = 1e-22
 Identities = 75/217 (34%), Positives = 104/217 (47%), Gaps = 18/217 (8%)

Query: 222 DSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG 281
           D  +CRRC +VGN G L     G  +D ++ ++R+N AP  GFE+DVGS+TT    YPE 
Sbjct: 145 DPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPES 204

Query: 282 AMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRIL 341
           A   P        FVL  FK  D  W+   +   ++  +    KS   RV KE  +++I 
Sbjct: 205 AKNLPANVS----FVLVPFKVLDLLWIASALSTGQIRFTYAPVKSF-LRVDKE--KVQIY 257

Query: 342 NPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAP 401
           NP F +           +      G  P+ G + +  ALH CDEV V GFG D S  N  
Sbjct: 258 NPAFFKYI--------HDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGAD-SRGNWH 308

Query: 402 LHYYETVRMAA-IKESWTHNIQREKEFLRKLVKARVI 437
            HY+E  R A   +++  H+   E   +  L KA  I
Sbjct: 309 -HYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKI 344


>gi|21264332 sialyltransferase 7A [Homo sapiens]
          Length = 600

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)

Query: 177 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 226
           +FLD       +W R+  F PPFG    + +L++ +++    V ++  L  +L   SLRC
Sbjct: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362

Query: 227 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 274
             C +VGNGG+L N  +G  ID +D V RL+ A +KG+E+DVG++T            +L
Sbjct: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422

Query: 275 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 330
            I    G    P   +   L  L G +  D++WL+ ++  + V + + FW       A R
Sbjct: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480

Query: 331 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 390
                    +L+P F++      +     +G   R   PT G++ +  AL  CD+V+  G
Sbjct: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540

Query: 391 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 431
           F   G++  +     HYY+T        SW        H+ + E+E  ++L
Sbjct: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579


>gi|192448440 sialyltransferase 7B [Homo sapiens]
          Length = 374

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)

Query: 186 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 239
           W R+ +   P+G +G  + + A    +L+ ++  +L  P  D+  +C RC +VGNGG+L 
Sbjct: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161

Query: 240 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 287
               G  ID +D V RLN A +KGFE+DVG+KT+             ++Y   G    P+
Sbjct: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221

Query: 288 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 343
             +   +F+ +  +  D+  L+  +    V   +G  K         P     + ++L+P
Sbjct: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277

Query: 344 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 403
            FI       +     N   G   +P+ G++ +  ALH CD+V+  GF    +      H
Sbjct: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336

Query: 404 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 437
           Y+E  +M  +     H++  E    R L KA ++
Sbjct: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369


>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)

Query: 216 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 270
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 271 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 327
           KTT+RI   +        +   SL+   +L  +    +     + YK+        +   
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397

Query: 328 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 387
             R P +P    IL+P FI +       +  N     + N P+ G + + + +  C EV 
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452

Query: 388 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 431
           V  + Y  S     L HY+E    AA      H +  EK  +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495


>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)

Query: 216 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 270
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 271 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 327
           KTT+RI   +        +   SL+   +L  +    +     + YK+        +   
Sbjct: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397

Query: 328 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 387
             R P +P    IL+P FI +       +  N     + N P+ G + + + +  C EV 
Sbjct: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452

Query: 388 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 431
           V  + Y  S     L HY+E    AA      H +  EK  +++L
Sbjct: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495


>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform b [Homo sapiens]
          Length = 466

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 216 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 270
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337

Query: 271 KTTLRI 276
           KTT+RI
Sbjct: 338 KTTIRI 343


>gi|5174677 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 2 [Homo sapiens]
          Length = 375

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/242 (23%), Positives = 98/242 (40%), Gaps = 48/242 (19%)

Query: 215 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 271
           Y L P    L+ +    C IVGN GVL N   G  ID +  V+R N APV+ + +DVG K
Sbjct: 140 YELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLK 199

Query: 272 TTL----------------RITYPEGAMQRPEQYERDSLFV---LAGFKWQDFKWLKYIV 312
           T L                  T+ E  +QR        L++   +A    +  +W+  ++
Sbjct: 200 TDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELI 259

Query: 313 YKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLG 372
            K  V+    +            P +R+L+          + G    N +  +   PT G
Sbjct: 260 LKHHVNVRTAY------------PSLRLLH---------AVRGYWLTNKVHIKR--PTTG 296

Query: 373 SVAVTMALHGCDEVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLR 429
            +  T+A   C ++ + G   F  D +      HYY++++     ++  H +  E + L+
Sbjct: 297 LLMYTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALK 356

Query: 430 KL 431
            L
Sbjct: 357 SL 358


>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
          Length = 302

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 49/200 (24%), Positives = 82/200 (41%), Gaps = 30/200 (15%)

Query: 226 CRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQR 285
           CR C +V + G +    LG+ ID  + V R+N AP  GFE DVG ++TLR+         
Sbjct: 73  CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 132

Query: 286 PEQYE------RDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIR 339
              Y       RD+L+++    W   + +  ++         G       ++ +  P ++
Sbjct: 133 LRNYSHYFQKARDTLYMV----WGQGRHMDRVL--------GGRTYRTLLQLTRMYPGLQ 180

Query: 340 ILNPYFIQEAAFTLIGLPFNN----GLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYD- 394
           +   Y   E         F +         G+  + G   + +AL  C+E+ V G   D 
Sbjct: 181 V---YTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237

Query: 395 ----MSTPNAPLHYYETVRM 410
                S P+ P HY+E  R+
Sbjct: 238 YCREKSHPSVPYHYFEKGRL 257


>gi|13569938 sialyltransferase 7E [Homo sapiens]
          Length = 336

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 24/195 (12%)

Query: 224 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAM 283
           + CR C +V + G L +   GS+ID  + V+R+N AP +G+ +DVG++T+LR+     ++
Sbjct: 91  MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRV-IAHSSI 149

Query: 284 QRPEQYERDSLFVLAG---FKWQDFKWL----KYIVYKERVSASDGFWKSVATRVPKEPP 336
           QR  +   D L V  G     W    ++    K  VY      S    +  A  + +   
Sbjct: 150 QRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRH-- 207

Query: 337 EIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG-----F 391
           ++   +  F QE   T      +N  +      + G   +T+AL  CD + V G     F
Sbjct: 208 KMLQFDELFKQE---TGKDRKISNTWL------STGWFTMTIALELCDRINVYGMVPPDF 258

Query: 392 GYDMSTPNAPLHYYE 406
             D + P+ P HYYE
Sbjct: 259 CRDPNHPSVPYHYYE 273


>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 228 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 287
           RC +V + G L +  LG  IDD+D V+R N AP   F++DVG+KTT+R+   +  +   +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241

Query: 288 QYERDSLF 295
           ++ +DSL+
Sbjct: 242 RFLKDSLY 249


>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 27/68 (39%), Positives = 44/68 (64%), Gaps = 1/68 (1%)

Query: 228 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPE 287
           RC +V + G L +  LG  IDD+D V+R N AP   F++DVG+KTT+R+   +  +   +
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ-LVTTEK 241

Query: 288 QYERDSLF 295
           ++ +DSL+
Sbjct: 242 RFLKDSLY 249


>gi|5031999 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
          Length = 359

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 56/230 (24%), Positives = 94/230 (40%), Gaps = 24/230 (10%)

Query: 215 YRLTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSK 271
           + L P +  ++ RR   C +VGN G+L +   G  ID ++ V+R N APV  F  DVG+K
Sbjct: 125 HSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTK 184

Query: 272 TTLRITYPEGAMQRP-----EQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKS 326
           +   IT     +QR       + +R+              W+   +    V   +   + 
Sbjct: 185 SDF-ITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFM----VKGGEKHVEW 239

Query: 327 VATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNI--PTLGSVAVTMALHGCD 384
           V   + K   ++R   P      +  LI       L  +  I  P+ G +  T+A   CD
Sbjct: 240 VNALILKNKLKVRTAYP------SLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCD 293

Query: 385 EVAVAG---FGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKL 431
           E+ + G   F  D++      HYY+ ++      +  H +  E + L  L
Sbjct: 294 EIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVL 343


>gi|110815855 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 3 [Homo sapiens]
          Length = 380

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)

Query: 206 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 261
           K + S++  +R L P +  +  +    C +VGN G+L     G  ID  D V R N AP 
Sbjct: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194

Query: 262 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 316
           + F++DVG KT L  T+    +++         +R++ F+          W+    +   
Sbjct: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253

Query: 317 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 367
            + +                  R L  +F++      + L +   +M   N         
Sbjct: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295

Query: 368 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 421
               + G +  T+A   C+E+ + G   FG+D +T  + P HYY+  +       W  + 
Sbjct: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354

Query: 422 QREKEF 427
           Q   EF
Sbjct: 355 QLPAEF 360


>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
          Length = 356

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)

Query: 224 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 282
           L  ++C +VGNGG+L     G +ID+ + V+R N  P+   + KDVGSK+ L    P   
Sbjct: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192

Query: 283 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 342
            QR +         +   K  +  ++    +  +                     +   N
Sbjct: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252

Query: 343 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 401
           P F++      IG  + +  +    + T G   V+ AL  C+EVA+ GF  + ++    P
Sbjct: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306

Query: 402 L--HYYETV 408
           +  HYY+ V
Sbjct: 307 ISHHYYDNV 315


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,491,838
Number of Sequences: 37866
Number of extensions: 791508
Number of successful extensions: 1593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1515
Number of HSP's gapped (non-prelim): 58
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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