Guide to the Human Genome
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Search of human proteins with 27436889

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27436889 protein O-fucosyltransferase 1 isoform 1 precursor
[Homo sapiens]
         (388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27436889 protein O-fucosyltransferase 1 isoform 1 precursor [...   811   0.0  
gi|27436891 protein O-fucosyltransferase 1 isoform 2 precursor [...   391   e-109
gi|34147487 protein O-fucosyltransferase 2 isoform C [Homo sapiens]    37   0.040
gi|5902106 SRY-box 15 [Homo sapiens]                                   32   1.3  
gi|197209974 coiled-coil and C2 domain containing 2A isoform a [...    31   2.2  
gi|197209817 coiled-coil and C2 domain containing 2A isoform b [...    31   2.2  
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              31   2.2  
gi|122937199 protein phosphatase 1B-like [Homo sapiens]                29   6.3  
gi|126723564 pecanex-like 1 [Homo sapiens]                             29   8.3  
gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens]    29   8.3  
gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens]      29   8.3  

>gi|27436889 protein O-fucosyltransferase 1 isoform 1 precursor
           [Homo sapiens]
          Length = 388

 Score =  811 bits (2095), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL 60
           MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL
Sbjct: 1   MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL 60

Query: 61  LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE 120
           LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE
Sbjct: 61  LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE 120

Query: 121 KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ 180
           KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ
Sbjct: 121 KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ 180

Query: 181 RFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIHLR 240
           RFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIHLR
Sbjct: 181 RFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIHLR 240

Query: 241 IGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRS 300
           IGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRS
Sbjct: 241 IGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRS 300

Query: 301 LDAQSVYVATDSESYVPELQQLFKGKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTA 360
           LDAQSVYVATDSESYVPELQQLFKGKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTA
Sbjct: 301 LDAQSVYVATDSESYVPELQQLFKGKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTA 360

Query: 361 FVKRERDLQGRPSSFFGMDRPPKLRDEF 388
           FVKRERDLQGRPSSFFGMDRPPKLRDEF
Sbjct: 361 FVKRERDLQGRPSSFFGMDRPPKLRDEF 388


>gi|27436891 protein O-fucosyltransferase 1 isoform 2 precursor
           [Homo sapiens]
          Length = 194

 Score =  391 bits (1005), Expect = e-109
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL 60
           MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL
Sbjct: 1   MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL 60

Query: 61  LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE 120
           LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE
Sbjct: 61  LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE 120

Query: 121 KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ 180
           KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ
Sbjct: 121 KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ 180

Query: 181 R 181
           R
Sbjct: 181 R 181


>gi|34147487 protein O-fucosyltransferase 2 isoform C [Homo sapiens]
          Length = 429

 Score = 36.6 bits (83), Expect = 0.040
 Identities = 85/379 (22%), Positives = 141/379 (37%), Gaps = 64/379 (16%)

Query: 34  YLLYC--PCMGRFGNQADHFLGSLAFAKLLNRT----LAVPPWIEYQH-HKPPFTNLHVS 86
           YLLY   P  G F  + D ++   +  K L +T    L +PPW    H   P    + + 
Sbjct: 45  YLLYDVNPPEG-FNLRRDVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIP 103

Query: 87  YQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPEKRVAYCFEVAAQRSPDKKTCPMKEGN 146
           + ++F L  L     VI  E F   +A +  P   +V Y  +  A+     K    +E  
Sbjct: 104 WSEFFDLPSLNKNIPVIEYEQF---IAESGGPFIDQV-YVLQSYAE---GWKEGTWEEKV 156

Query: 147 PFGPFWDQFHVSFNKSELFTGISFSASYREQ-------WSQRFSPKEHPVLALPGAPAQF 199
              P  DQ   S +K E + G  +   Y E         S + S      L L    A+ 
Sbjct: 157 DERPCIDQLLYSQDKHEYYRGWFWG--YEETRGLNVSCLSVQGSASIVAPLLLRNTSARS 214

Query: 200 PVLE-------------EHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIHLRIGSDWK 246
            +L+             E+   ++ MV++  + + G+     HL        +    DW 
Sbjct: 215 VMLDRAENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWM 274

Query: 247 NACAMLKDGTAGS----HFMASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRSLD 302
                L     G     H        G+ +           +P L+   R ++  +++  
Sbjct: 275 KMKVKLGSALGGPYLGVHLRRKDFIWGHRQD----------VPSLEGAVRKIRSLMKTHR 324

Query: 303 AQSVYVATDSESYVPELQQLFKGKVKVVSLKPE-----------VAQVDLYILGQADHFI 351
              V+VATD+     E ++L K   ++V  +P            VA +D +I   A  FI
Sbjct: 325 LDKVFVATDAVR--KEYEELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARFFI 382

Query: 352 GNCVSSFTAFVKRERDLQG 370
           G  VS+F+  +  ER++ G
Sbjct: 383 GTSVSTFSFRIHEEREILG 401


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 179 SQRFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIH 238
           S    P+E      P AP   P+ +  RP+  +MVWS    +   AQ +  +      I 
Sbjct: 24  SSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQ-RRQMAQQNPKMHNS--EIS 80

Query: 239 LRIGSDWK 246
            R+G+ WK
Sbjct: 81  KRLGAQWK 88


>gi|197209974 coiled-coil and C2 domain containing 2A isoform a [Homo
            sapiens]
          Length = 1620

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 13/87 (14%)

Query: 13   SFLLLLLPLPGMPAG---SWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPP 69
            ++LL+   +P  P     +W+   YL++ PC G F  Q D       F  L N    + P
Sbjct: 1383 AWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFD------TFCPLKNVGCLIGP 1436

Query: 70   ---WIEYQHHKPPF-TNLHVSYQKYFK 92
               W   Q ++ P   N  V+  K +K
Sbjct: 1437 DNIWFNIQRYESPLRINFDVTRPKLWK 1463


>gi|197209817 coiled-coil and C2 domain containing 2A isoform b [Homo
            sapiens]
          Length = 1512

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 13/87 (14%)

Query: 13   SFLLLLLPLPGMPAG---SWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPP 69
            ++LL+   +P  P     +W+   YL++ PC G F  Q D       F  L N    + P
Sbjct: 1275 AWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFD------TFCPLKNVGCLIGP 1328

Query: 70   ---WIEYQHHKPPF-TNLHVSYQKYFK 92
               W   Q ++ P   N  V+  K +K
Sbjct: 1329 DNIWFNIQRYESPLRINFDVTRPKLWK 1355


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 4/57 (7%)

Query: 174  YREQWSQRFSPKEHPVLALPGAP----AQFPVLEEHRPLQKYMVWSDEMVKTGEAQI 226
            ++ +W  R SP++    +LP  P    A  P+ E  R  +   + SD +V +G ++I
Sbjct: 1379 HQSEWEGRISPEQVDTSSLPLVPQHSFASLPLNESERNQEPCSINSDNIVSSGHSEI 1435


>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
          Length = 430

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 18/85 (21%)

Query: 128 EVAAQRSPDKK----TCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQRFS 183
           E A +R+P+      T P +   P G            +E   G+ F AS  + W  R  
Sbjct: 32  EEAGRRAPEGPRSLLTAPRRAQRPHGG-----------AEASGGLRFGASAAQGWRARME 80

Query: 184 PKEHPVLALPGAP---AQFPVLEEH 205
                 L+LPG P   A F VL+ H
Sbjct: 81  DAHCTWLSLPGLPPGWALFAVLDGH 105


>gi|126723564 pecanex-like 1 [Homo sapiens]
          Length = 2341

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 14/46 (30%), Positives = 28/46 (60%)

Query: 299  RSLDAQSVYVATDSESYVPELQQLFKGKVKVVSLKPEVAQVDLYIL 344
            R+L   S +++++ ES++  L  LFKG  ++ S++ E    D+ +L
Sbjct: 1802 RALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELL 1847


>gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens]
          Length = 331

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 30/143 (20%), Positives = 54/143 (37%), Gaps = 18/143 (12%)

Query: 170 FSASYREQWSQRFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAH 229
           +S ++  +WSQ   PK++P+      PAQ+  L        Y +W               
Sbjct: 43  YSITFTGKWSQTAFPKQYPLFR---PPAQWSSLLGAAHSSDYSMWRKNQ----------- 88

Query: 230 LVRPYVGIHLRIGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKE 289
               YV   LR  ++   A A++K+  A    + S   V  + +  +    T    +++ 
Sbjct: 89  ----YVSNGLRDFAERGEAWALMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQR 144

Query: 290 IQRAVKLWVRSLDAQSVYVATDS 312
               V   VR + +   +V  DS
Sbjct: 145 RHSLVSFVVRIVPSPDWFVGVDS 167


>gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens]
          Length = 331

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 30/143 (20%), Positives = 54/143 (37%), Gaps = 18/143 (12%)

Query: 170 FSASYREQWSQRFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAH 229
           +S ++  +WSQ   PK++P+      PAQ+  L        Y +W               
Sbjct: 43  YSITFTGKWSQTAFPKQYPLFR---PPAQWSSLLGAAHSSDYSMWRKNQ----------- 88

Query: 230 LVRPYVGIHLRIGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKE 289
               YV   LR  ++   A A++K+  A    + S   V  + +  +    T    +++ 
Sbjct: 89  ----YVSNGLRDFAERGEAWALMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQR 144

Query: 290 IQRAVKLWVRSLDAQSVYVATDS 312
               V   VR + +   +V  DS
Sbjct: 145 RHSLVSFVVRIVPSPDWFVGVDS 167


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,721,460
Number of Sequences: 37866
Number of extensions: 777876
Number of successful extensions: 1550
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1540
Number of HSP's gapped (non-prelim): 16
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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