Guide to the Human Genome
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Search of human proteins with 26787978

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26787978 interleukin 13 precursor [Homo sapiens]
         (146 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26787978 interleukin 13 precursor [Homo sapiens]                   291   1e-79
gi|24430210 interleukin 17 receptor E isoform 1 [Homo sapiens]         30   0.73 
gi|24430206 interleukin 17 receptor E isoform 2 [Homo sapiens]         30   0.73 
gi|24430204 interleukin 17 receptor E isoform 1 [Homo sapiens]         30   0.73 
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo...    29   1.2  
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap...    29   1.2  
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat...    29   1.6  
gi|119964718 desmoglein 3 preproprotein [Homo sapiens]                 28   2.8  
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    28   3.6  
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         28   3.6  
gi|21389623 prominin 2 [Homo sapiens]                                  27   4.7  
gi|13449277 cytochrome P450, family 2, subfamily S, polypeptide ...    27   6.2  

>gi|26787978 interleukin 13 precursor [Homo sapiens]
          Length = 146

 Score =  291 bits (746), Expect = 1e-79
 Identities = 146/146 (100%), Positives = 146/146 (100%)

Query: 1   MHPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAP 60
           MHPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAP
Sbjct: 1   MHPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAP 60

Query: 61  LCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRD 120
           LCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRD
Sbjct: 61  LCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRD 120

Query: 121 TKIEVAQFVKDLLLHLKKLFREGQFN 146
           TKIEVAQFVKDLLLHLKKLFREGQFN
Sbjct: 121 TKIEVAQFVKDLLLHLKKLFREGQFN 146


>gi|24430210 interleukin 17 receptor E isoform 1 [Homo sapiens]
          Length = 667

 Score = 30.0 bits (66), Expect = 0.73
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 8/57 (14%)

Query: 5   LNPLLLALGLMALLLTTVIALTCLGGFASPGPVPP--------STALRELIEELVNI 53
           L  L+LAL  +  LL  V+ALTC    + PGP  P        S A R L+  L  +
Sbjct: 455 LGLLILALLALLTLLGVVLALTCRRPQSGPGPARPVLLLHAADSEAQRRLVGALAEL 511


>gi|24430206 interleukin 17 receptor E isoform 2 [Homo sapiens]
          Length = 551

 Score = 30.0 bits (66), Expect = 0.73
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 8/57 (14%)

Query: 5   LNPLLLALGLMALLLTTVIALTCLGGFASPGPVPP--------STALRELIEELVNI 53
           L  L+LAL  +  LL  V+ALTC    + PGP  P        S A R L+  L  +
Sbjct: 339 LGLLILALLALLTLLGVVLALTCRRPQSGPGPARPVLLLHAADSEAQRRLVGALAEL 395


>gi|24430204 interleukin 17 receptor E isoform 1 [Homo sapiens]
          Length = 667

 Score = 30.0 bits (66), Expect = 0.73
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 8/57 (14%)

Query: 5   LNPLLLALGLMALLLTTVIALTCLGGFASPGPVPP--------STALRELIEELVNI 53
           L  L+LAL  +  LL  V+ALTC    + PGP  P        S A R L+  L  +
Sbjct: 455 LGLLILALLALLTLLGVVLALTCRRPQSGPGPARPVLLLHAADSEAQRRLVGALAEL 511


>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
            sapiens]
          Length = 1544

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 8/97 (8%)

Query: 47   IEELVNITQNQKAPLCNGSMVWSIN--LTAGMYCAALESLINVSGCSAIEKTQRMLSGFC 104
            +EEL N+   ++  +  G +VW +N   T  +Y   LE ++ +     ++K    L   C
Sbjct: 1007 VEELRNLDLTKRKMIHEGPLVWKVNRDKTIDLYTLLLEDILVL-----LQKQDDRLVLRC 1061

Query: 105  PHKVSAGQFSSLHVRDTKIEVAQ-FVKDLLLHLKKLF 140
              K+ A    S H     I+++   V+ +    K LF
Sbjct: 1062 HSKILASTADSKHTFSPVIKLSTVLVRQVATDNKALF 1098


>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
          Length = 4486

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 13/37 (35%), Positives = 23/37 (62%)

Query: 93   IEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFV 129
            +E+ QRM+   C ++ +  Q+S L+V D K  + QF+
Sbjct: 993  MERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFL 1029


>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase
          activating protein 11 [Homo sapiens]
          Length = 550

 Score = 28.9 bits (63), Expect = 1.6
 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)

Query: 28 LGGFASPGPVPPSTALRELIEELVNITQNQKAPLCNGSMVWS 69
          L  ++S  P+ PST+  +L    V  T N   P+C  SM WS
Sbjct: 50 LNNYSSSIPLTPSTSQEDLYFS-VPPTANTPTPICKQSMGWS 90


>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
          Length = 999

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 15/29 (51%), Positives = 18/29 (62%)

Query: 9   LLALGLMALLLTTVIALTCLGGFASPGPV 37
           LL LGL+ LLL  ++ LTC  G  S G V
Sbjct: 623 LLLLGLLLLLLAPLLLLTCDCGAGSTGGV 651


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 27.7 bits (60), Expect = 3.6
 Identities = 12/34 (35%), Positives = 19/34 (55%), Gaps = 4/34 (11%)

Query: 45  ELIEELVNITQNQKAPLCNGSMVWSINLTAGMYC 78
           E+I+ L  +T N + P+   S++W I    G YC
Sbjct: 483 EIIKHLAKLTDNIQVPMARASILWLI----GEYC 512


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 27.7 bits (60), Expect = 3.6
 Identities = 16/63 (25%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 81  LESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLF 140
           L+ L++V   S++++T  ML    P  ++A + S + + +   +  + V+ ++ HL++  
Sbjct: 251 LQDLVSVFPASSVQETS-MLVSLLPTSLNALRASGVDIEEETEKNLEKVQTIIEHLQEKR 309

Query: 141 REG 143
           REG
Sbjct: 310 REG 312


>gi|21389623 prominin 2 [Homo sapiens]
          Length = 834

 Score = 27.3 bits (59), Expect = 4.7
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 9/73 (12%)

Query: 7   PLLLALGLMALLLTTVIALTC-------LGGFA-SPGPVPPSTALRELIEELVNITQNQK 58
           PL+L +    L+   V  L C       L  FA +PG +PPS  L +L+    NI+ +Q 
Sbjct: 487 PLILLVFATFLVGGNVQTLVCRSWENGELFEFADTPGNLPPSMNLSQLLGLRKNISIHQA 546

Query: 59  APLC-NGSMVWSI 70
              C  G+ +W++
Sbjct: 547 YQQCKEGAALWTV 559


>gi|13449277 cytochrome P450, family 2, subfamily S, polypeptide 1
          [Homo sapiens]
          Length = 504

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 1/31 (3%)

Query: 8  LLLALGLMALLLTTVIALTCLGGFASPGPVP 38
          LLLAL L+ LLLT  ++ T   G   PGP P
Sbjct: 9  LLLALALL-LLLTLALSGTRARGHLPPGPTP 38


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,417,894
Number of Sequences: 37866
Number of extensions: 212015
Number of successful extensions: 677
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 671
Number of HSP's gapped (non-prelim): 12
length of query: 146
length of database: 18,247,518
effective HSP length: 92
effective length of query: 54
effective length of database: 14,763,846
effective search space: 797247684
effective search space used: 797247684
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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