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Search of human proteins with 25121970
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
(393 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 795 0.0
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 558 e-159
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 521 e-148
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 440 e-124
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 395 e-110
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 390 e-108
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 382 e-106
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 382 e-106
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 382 e-106
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 379 e-105
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 379 e-105
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 379 e-105
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 358 5e-99
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 358 5e-99
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 351 7e-97
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 341 8e-94
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 306 2e-83
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 306 2e-83
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 306 2e-83
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 306 2e-83
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 306 2e-83
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 286 2e-77
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 286 2e-77
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 286 2e-77
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 273 2e-73
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 238 5e-63
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 238 5e-63
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 238 5e-63
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 187 2e-47
gi|6912446 potassium voltage-gated channel, subfamily H, member ... 32 1.3
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 795 bits (2052), Expect = 0.0
Identities = 393/393 (100%), Positives = 393/393 (100%)
Query: 1 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS 60
MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS
Sbjct: 1 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS 60
Query: 61 LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT 120
LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT
Sbjct: 61 LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT 120
Query: 121 IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS 180
IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS
Sbjct: 121 IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS 180
Query: 181 LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF 240
LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF
Sbjct: 181 LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF 240
Query: 241 LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW 300
LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW
Sbjct: 241 LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW 300
Query: 301 GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK 360
GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK
Sbjct: 301 GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK 360
Query: 361 VEEEGAGEGAGGEAGADKEQNGCLPPPESESKV 393
VEEEGAGEGAGGEAGADKEQNGCLPPPESESKV
Sbjct: 361 VEEEGAGEGAGGEAGADKEQNGCLPPPESESKV 393
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 558 bits (1439), Expect = e-159
Identities = 270/376 (71%), Positives = 320/376 (85%), Gaps = 2/376 (0%)
Query: 18 RRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGA 77
+R QRYV KDG+CNV GNVRETYRYLTD+FTTLVDL+WR +LL FV+ Y +TWLFFG
Sbjct: 50 KRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGM 109
Query: 78 IWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIV 137
IWWLIAY RGD++H+ED +WTPCV NLNGFV+AFLFSIETETTIGYG+RVITD+CPEGI+
Sbjct: 110 IWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGII 169
Query: 138 LLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRS 197
LLL+Q++LGS+VNAFMVGCMFVKISQP KRA TLVFS+HAV+S+RDG+LCLMFRVGDLR+
Sbjct: 170 LLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRN 229
Query: 198 SHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPF 257
SHIVEASIRAKLI+S+QT EGEFIPL+QTD++VG+ TGDDRLFLVSPL+ISHEI+ SPF
Sbjct: 230 SHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPF 289
Query: 258 WEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEV 317
WE S+ L +++ EIVVILEGMVEATGMTCQARSSY+ E+LWG+RFT VLTLEDGFYEV
Sbjct: 290 WEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEV 349
Query: 318 DYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGAD 377
DY SFHET+E TPS SA+ELAE A+R + L WS+ S+L++ E E E E
Sbjct: 350 DYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLE--EQ 407
Query: 378 KEQNGCLPPPESESKV 393
E+NG + E+ESKV
Sbjct: 408 TERNGDVANLENESKV 423
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 521 bits (1342), Expect = e-148
Identities = 258/371 (69%), Positives = 305/371 (82%), Gaps = 14/371 (3%)
Query: 18 RRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGA 77
++ RQRY+EK G+CNV GNV+ETYRYL+DLFTTLVDL+WR +LL F + Y +TWLFFG
Sbjct: 47 KKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGF 106
Query: 78 IWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIV 137
IWWLIAY RGDL+H+ D W PCV NL+GFV+AFLFSIETETTIGYG RVIT++CPEGI+
Sbjct: 107 IWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGII 166
Query: 138 LLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRS 197
LLL+QAILGS+VNAFMVGCMFVKISQP KRA TL+FS++AV+S+RD +LCLMFRVGDLR+
Sbjct: 167 LLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRN 226
Query: 198 SHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPF 257
SHIVEASIRAKLI+SRQT EGEFIPL+QTD++VGFDTGDDRLFLVSPL+ISHEI+ SPF
Sbjct: 227 SHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPF 286
Query: 258 WEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEV 317
WE S+ L +++FE+VVILEGMVEATGMTCQARSSY+ EVLWGHRFT VLTLE GFYEV
Sbjct: 287 WEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEV 346
Query: 318 DYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPS----------RLDEKVE--EEG 365
DY +FH+T+E TPSC A+ELAE + + L +PS LD + E EE
Sbjct: 347 DYNTFHDTYETNTPSCCAKELAE--MKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
Query: 366 AGEGAGGEAGA 376
+G GG A
Sbjct: 405 EPKGLGGSREA 415
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 440 bits (1132), Expect = e-124
Identities = 210/332 (63%), Positives = 267/332 (80%), Gaps = 2/332 (0%)
Query: 10 PGQEEPPRRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAY 68
P Q+ P+++ RQR+V+K+GRCNVQ GN+ ET RYL+DLFTTLVDL+WR +L F+L Y
Sbjct: 33 PQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTY 91
Query: 69 ALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVI 128
+ WLF ++WW+IAY RGDL +TPCV N+ F +AFLF IETE TIGYG+R I
Sbjct: 92 TVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYI 151
Query: 129 TDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCL 188
TD+CPEGI+L L Q+ILGS+V+AF++GCMF+K+SQP KRA TL+FS HAV+S+RDG+L L
Sbjct: 152 TDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTL 211
Query: 189 MFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVIS 248
MFRVG+LR+SH+V A IR KL++SRQT EGEF+PL Q +L VGF TG D+LFLVSPL I
Sbjct: 212 MFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTIC 271
Query: 249 HEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVL 308
H IDA SPF++ S+R+++ + FEIVVILEG+VE TGMTCQAR+SY DEVLWGHRF V+
Sbjct: 272 HVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVI 331
Query: 309 TLEDGFYEVDYASFHETFEVPTPSCSARELAE 340
+LE+GF++VDY+ FH TFEVPTP S +E E
Sbjct: 332 SLEEGFFKVDYSQFHATFEVPTPPYSVKEQEE 363
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 395 bits (1016), Expect = e-110
Identities = 199/360 (55%), Positives = 266/360 (73%), Gaps = 7/360 (1%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
RRR R R+V+K+G+CN++ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 39 RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G I+W+IA GDLE E TPCV ++GF+AAFLFSIET+TTIGYG R +T++CP
Sbjct: 99 GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+ +++ Q+I+G ++++FM+G + K+++P KRA TL+FS +AVV+LRDG+LCLM+RVG+L
Sbjct: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G DR+FLVSP+ I HEID AS
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEAS 278
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + SR+ LE DDFEIVVILEGMVEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 279 PLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
Query: 316 EVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL-----DEKVEEEGAGEG 369
++DY+ FH+T+EVP TP CSA++L E L + + + L DE+ E +G +G
Sbjct: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDG 398
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 390 bits (1002), Expect = e-108
Identities = 198/360 (55%), Positives = 264/360 (73%), Gaps = 7/360 (1%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
RRR R R+V+K+G+CN+ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G I+W+IA GDLE E TPCV ++GF+AAFLFSIET+TTIGYG R +T++C
Sbjct: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+ +++ Q+I+G ++++FM+G + K+++P KRA TL+FS +AVV+LRDG+LCLM+RVG+L
Sbjct: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G DR+FLVSP+ I HEID AS
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEAS 278
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + SR+ LE DDFEIVVILEGMVEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 279 PLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
Query: 316 EVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL-----DEKVEEEGAGEG 369
++DY+ FH+T+EVP TP CSA++L E L + + + L DE+ E +G +G
Sbjct: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDG 398
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 382 bits (982), Expect = e-106
Identities = 185/326 (56%), Positives = 253/326 (77%), Gaps = 4/326 (1%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNVRET-YRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
R++ R R+V+KDG CNVQ NV E RYL D+FTT VD++WR L+ F LA+ L+WLFF
Sbjct: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G ++WLIA GDL+ ++ CV+ +N F AAFLFSIET+TTIGYG R +TD+CP
Sbjct: 100 GCVFWLIALLHGDLDASKEGK--ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIA 157
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+ +++ Q+I+G +++AF++G + K+++P KR TLVFS +AV+++RDG+LCLM+RVG+L
Sbjct: 158 VFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNL 217
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R SH+VEA +RA+L++SR T EGE+IPL Q D++VGFD+G DR+FLVSP+ I HEID S
Sbjct: 218 RKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDS 277
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P ++ S++ ++ DFEIVVILEGMVEAT MT Q RSSYL +E+LWGHR+ VL E +Y
Sbjct: 278 PLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYY 337
Query: 316 EVDYASFHETFEVP-TPSCSARELAE 340
+VDY+ FH+T+EVP TP CSAR+LAE
Sbjct: 338 KVDYSRFHKTYEVPNTPLCSARDLAE 363
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 382 bits (982), Expect = e-106
Identities = 197/403 (48%), Positives = 275/403 (68%), Gaps = 34/403 (8%)
Query: 11 GQEEPPRRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYA 69
GQ PRR+ R R+V+K+G+CNV N+ ++ RY+ D+FTT VD +WR L+ F A+
Sbjct: 8 GQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFL 67
Query: 70 LTWLFFGAIWWLIAYGRGDLEH----------------LEDTAWTPCVNNLNGFVAAFLF 113
++WLFFG ++W IA+ GDLE A PC+ ++NGF+ AFLF
Sbjct: 68 VSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLF 127
Query: 114 SIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVF 173
S+ET+TTIGYG R +T++CP ++ +++Q+I+G ++++FM+G + K+++P KRA TL+F
Sbjct: 128 SVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLF 187
Query: 174 SSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFD 233
S HAV+S+RDG+LCLM+RVG+LR SHIVEA +RA+LI+ T EGE++PL Q DL+VG+D
Sbjct: 188 SHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYD 247
Query: 234 TGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSY 293
G DR+FLVSP++I HEID SP + + LE +DFEIVVILEGMVEAT MT QARSSY
Sbjct: 248 IGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSY 307
Query: 294 LVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAARL------- 345
L E+LWGHRF V+ E Y+VDY+ FH+T+EV TP CSAREL E+ +
Sbjct: 308 LASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPP 367
Query: 346 -DAHLY---WSIPSRLDEKVEEEGA-----GEGAGGEAGADKE 379
A Y ++ S+ +E++EEE A G G EAG+ +E
Sbjct: 368 PSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEE 410
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 382 bits (982), Expect = e-106
Identities = 197/403 (48%), Positives = 275/403 (68%), Gaps = 34/403 (8%)
Query: 11 GQEEPPRRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYA 69
GQ PRR+ R R+V+K+G+CNV N+ ++ RY+ D+FTT VD +WR L+ F A+
Sbjct: 8 GQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFL 67
Query: 70 LTWLFFGAIWWLIAYGRGDLEH----------------LEDTAWTPCVNNLNGFVAAFLF 113
++WLFFG ++W IA+ GDLE A PC+ ++NGF+ AFLF
Sbjct: 68 VSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLF 127
Query: 114 SIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVF 173
S+ET+TTIGYG R +T++CP ++ +++Q+I+G ++++FM+G + K+++P KRA TL+F
Sbjct: 128 SVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLF 187
Query: 174 SSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFD 233
S HAV+S+RDG+LCLM+RVG+LR SHIVEA +RA+LI+ T EGE++PL Q DL+VG+D
Sbjct: 188 SHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYD 247
Query: 234 TGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSY 293
G DR+FLVSP++I HEID SP + + LE +DFEIVVILEGMVEAT MT QARSSY
Sbjct: 248 IGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSY 307
Query: 294 LVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAARL------- 345
L E+LWGHRF V+ E Y+VDY+ FH+T+EV TP CSAREL E+ +
Sbjct: 308 LASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPPP 367
Query: 346 -DAHLY---WSIPSRLDEKVEEEGA-----GEGAGGEAGADKE 379
A Y ++ S+ +E++EEE A G G EAG+ +E
Sbjct: 368 PSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEE 410
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 379 bits (973), Expect = e-105
Identities = 191/360 (53%), Positives = 258/360 (71%), Gaps = 6/360 (1%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
RRR R+V+K+G+CN++ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G I+W+IA GDLE E TPCV ++GF+AAFLFSI+T+ TI YG R +T++CP
Sbjct: 99 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 158
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+ +++ Q+I+G ++N+FM+G + K+ +P KRA TL+FS +AVV+LRDG+LC M+RVG+L
Sbjct: 159 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 218
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G D FLVSP+ I HEID AS
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 278
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + SR+ L+ DDFEIV+ILEG+VEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 279 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 337
Query: 316 EVDYASFHETFEVP-TPSCSARELAE---AAARLDAHLYWSIPSRLDEKVEEEGAGEGAG 371
++DY FH+T+EVP TP CSA++L E R ++ Y + + L E+E G+ G
Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDG 397
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 379 bits (973), Expect = e-105
Identities = 191/360 (53%), Positives = 258/360 (71%), Gaps = 6/360 (1%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
RRR R+V+K+G+CN++ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G I+W+IA GDLE E TPCV ++GF+AAFLFSI+T+ TI YG R +T++CP
Sbjct: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+ +++ Q+I+G ++N+FM+G + K+ +P KRA TL+FS +AVV+LRDG+LC M+RVG+L
Sbjct: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G D FLVSP+ I HEID AS
Sbjct: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + SR+ L+ DDFEIV+ILEG+VEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439
Query: 316 EVDYASFHETFEVP-TPSCSARELAE---AAARLDAHLYWSIPSRLDEKVEEEGAGEGAG 371
++DY FH+T+EVP TP CSA++L E R ++ Y + + L E+E G+ G
Sbjct: 440 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDG 499
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 379 bits (973), Expect = e-105
Identities = 191/360 (53%), Positives = 258/360 (71%), Gaps = 6/360 (1%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
RRR R+V+K+G+CN++ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G I+W+IA GDLE E TPCV ++GF+AAFLFSI+T+ TI YG R +T++CP
Sbjct: 99 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 158
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+ +++ Q+I+G ++N+FM+G + K+ +P KRA TL+FS +AVV+LRDG+LC M+RVG+L
Sbjct: 159 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 218
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G D FLVSP+ I HEID AS
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 278
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + SR+ L+ DDFEIV+ILEG+VEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 279 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 337
Query: 316 EVDYASFHETFEVP-TPSCSARELAE---AAARLDAHLYWSIPSRLDEKVEEEGAGEGAG 371
++DY FH+T+EVP TP CSA++L E R ++ Y + + L E+E G+ G
Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDG 397
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 358 bits (919), Expect = 5e-99
Identities = 187/352 (53%), Positives = 244/352 (69%), Gaps = 4/352 (1%)
Query: 8 FSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVR-ETYRYLTDLFTTLVDLQWRLSLLFFVL 66
++P + P R R R+V+KDG CNV+ N+ + RYL+DLFTT VD++WR L F
Sbjct: 36 WAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSC 95
Query: 67 AYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHR 126
++ +WL FG +WLIA GDL A PC +++ F+AAFLF++ET+T+IGYG R
Sbjct: 96 SFLASWLLFGLAFWLIASLHGDLAAPPPPA--PCFSHVASFLAAFLFALETQTSIGYGVR 153
Query: 127 VITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRL 186
+T++CP + ++LQ I G +++AF+VG + K+++P KR TLVFS +AVV+LRD RL
Sbjct: 154 SVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRL 213
Query: 187 CLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLV 246
CLM+RVG+LR SH+VEA +RA+L++ R T EGE+IPL D+ VGFD G DR+FLVSP+
Sbjct: 214 CLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPIT 273
Query: 247 ISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTS 306
I HEID+ASP +E R L R DFE+VVILEGMVEAT MT Q RSSYL E+LWGHRF
Sbjct: 274 IVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEP 333
Query: 307 VLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL 357
VL YEVDY FH T+EVP TP CSA+EL E A + L S P L
Sbjct: 334 VLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSL 385
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 358 bits (919), Expect = 5e-99
Identities = 187/352 (53%), Positives = 244/352 (69%), Gaps = 4/352 (1%)
Query: 8 FSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVR-ETYRYLTDLFTTLVDLQWRLSLLFFVL 66
++P + P R R R+V+KDG CNV+ N+ + RYL+DLFTT VD++WR L F
Sbjct: 36 WAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSC 95
Query: 67 AYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHR 126
++ +WL FG +WLIA GDL A PC +++ F+AAFLF++ET+T+IGYG R
Sbjct: 96 SFLASWLLFGLAFWLIASLHGDLAAPPPPA--PCFSHVASFLAAFLFALETQTSIGYGVR 153
Query: 127 VITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRL 186
+T++CP + ++LQ I G +++AF+VG + K+++P KR TLVFS +AVV+LRD RL
Sbjct: 154 SVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRL 213
Query: 187 CLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLV 246
CLM+RVG+LR SH+VEA +RA+L++ R T EGE+IPL D+ VGFD G DR+FLVSP+
Sbjct: 214 CLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPIT 273
Query: 247 ISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTS 306
I HEID+ASP +E R L R DFE+VVILEGMVEAT MT Q RSSYL E+LWGHRF
Sbjct: 274 IVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEP 333
Query: 307 VLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL 357
VL YEVDY FH T+EVP TP CSA+EL E A + L S P L
Sbjct: 334 VLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSL 385
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 351 bits (900), Expect = 7e-97
Identities = 173/341 (50%), Positives = 239/341 (70%), Gaps = 7/341 (2%)
Query: 13 EEP--PRRRGRQR---YVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLA 67
E+P PR R RQR +V K G CNV N+RE R+L D+FTTLVDL+W +LL F ++
Sbjct: 19 EDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMS 78
Query: 68 YALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRV 127
+ +WL F WWLIA+ GDL E TA PCV +++ F +AFLFSIE + TIG+G R+
Sbjct: 79 FLCSWLLFAMAWWLIAFAHGDLAPSEGTA-EPCVTSIHSFSSAFLFSIEVQVTIGFGGRM 137
Query: 128 ITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLC 187
+T++CP I++L++Q I+G M+NA M+GC+F+K +Q ++RA TL+FS HAV++LR GRLC
Sbjct: 138 VTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLC 197
Query: 188 LMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVI 247
M RVGDLR S I+ A+I +++R + EGE +PLHQ D+ + G + +FLV+PL+I
Sbjct: 198 FMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLII 257
Query: 248 SHEIDAASPFWEASRRAL-ERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTS 306
H IDA SP ++ + L D EI+VILEG+VE TG+T QAR+SYL DE+LWG RF
Sbjct: 258 YHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVP 317
Query: 307 VLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA 347
++ EDG Y VDY+ F T +VPTP C+AR+L E + L+A
Sbjct: 318 IVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEA 358
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 341 bits (874), Expect = 8e-94
Identities = 160/336 (47%), Positives = 233/336 (69%), Gaps = 11/336 (3%)
Query: 16 PRRRGR---QRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTW 72
PR R R R++ K G CN+ N+RE R+L D+FTTLVDL+WR +L+ F +++ +W
Sbjct: 25 PRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSW 84
Query: 73 LFFGAIWWLIAYGRGDL-EHLEDTAW-------TPCVNNLNGFVAAFLFSIETETTIGYG 124
L F +WWL+A+ GD+ ++E + T CV N+ F +AFLFSIE + TIG+G
Sbjct: 85 LLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFG 144
Query: 125 HRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDG 184
R++T++CP I +L+LQ I+G ++NA M+GC+F+K +Q ++RA TL+FS HAV+++R+G
Sbjct: 145 GRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNG 204
Query: 185 RLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSP 244
+LC MFRVGDLR S I+ AS+R ++++ T EGE +P+HQ D+ V + +FLV+P
Sbjct: 205 KLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAP 264
Query: 245 LVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRF 304
L+I H ID SP ++ S L D E++VILEG+VE TG+T QAR+SY+ +E+ WGHRF
Sbjct: 265 LIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRF 324
Query: 305 TSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAE 340
S++T E+G Y VDY+ F T +V P CSAREL E
Sbjct: 325 VSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE 360
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 306 bits (785), Expect = 2e-83
Identities = 149/320 (46%), Positives = 216/320 (67%), Gaps = 4/320 (1%)
Query: 19 RGRQRYVEKDGRCNVQQGNVRETYRYL--TDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
R R R V KDGRCN++ GNV R++ D++TT++DL+WR + F+ A+ +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
+W+ +AY DL +A TPCV N+NG +AFLFS+ET+ TIGYG R +T+QC
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q+ILG ++N+FM G + KIS+P KRA T+ FS +AV+S R G+LCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S ++ + I KL+++ T EGE I L Q +++ D G++ LF +SPL I H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLT-LEDGF 314
PF+ + L + DFE+VV L+G VE+T TCQ R+SY+ +EVLWG+RF +++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 315 YEVDYASFHETFEVPTPSCS 334
Y VD+ +F +T EV TP C+
Sbjct: 318 YRVDFHNFSKTVEVETPHCA 337
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 306 bits (785), Expect = 2e-83
Identities = 149/320 (46%), Positives = 216/320 (67%), Gaps = 4/320 (1%)
Query: 19 RGRQRYVEKDGRCNVQQGNVRETYRYL--TDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
R R R V KDGRCN++ GNV R++ D++TT++DL+WR + F+ A+ +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
+W+ +AY DL +A TPCV N+NG +AFLFS+ET+ TIGYG R +T+QC
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q+ILG ++N+FM G + KIS+P KRA T+ FS +AV+S R G+LCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S ++ + I KL+++ T EGE I L Q +++ D G++ LF +SPL I H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLT-LEDGF 314
PF+ + L + DFE+VV L+G VE+T TCQ R+SY+ +EVLWG+RF +++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 315 YEVDYASFHETFEVPTPSCS 334
Y VD+ +F +T EV TP C+
Sbjct: 318 YRVDFHNFSKTVEVETPHCA 337
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 306 bits (785), Expect = 2e-83
Identities = 149/320 (46%), Positives = 216/320 (67%), Gaps = 4/320 (1%)
Query: 19 RGRQRYVEKDGRCNVQQGNVRETYRYL--TDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
R R R V KDGRCN++ GNV R++ D++TT++DL+WR + F+ A+ +W FFG
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
+W+ +AY DL +A TPCV N+NG +AFLFS+ET+ TIGYG R +T+QC
Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q+ILG ++N+FM G + KIS+P KRA T+ FS +AV+S R G+LCL+ RV +L
Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S ++ + I KL+++ T EGE I L Q +++ D G++ LF +SPL I H ID S
Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 276
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLT-LEDGF 314
PF+ + L + DFE+VV L+G VE+T TCQ R+SY+ +EVLWG+RF +++ ++G
Sbjct: 277 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 336
Query: 315 YEVDYASFHETFEVPTPSCS 334
Y VD+ +F +T EV TP C+
Sbjct: 337 YRVDFHNFSKTVEVETPHCA 356
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 306 bits (785), Expect = 2e-83
Identities = 149/320 (46%), Positives = 216/320 (67%), Gaps = 4/320 (1%)
Query: 19 RGRQRYVEKDGRCNVQQGNVRETYRYL--TDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
R R R V KDGRCN++ GNV R++ D++TT++DL+WR + F+ A+ +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
+W+ +AY DL +A TPCV N+NG +AFLFS+ET+ TIGYG R +T+QC
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q+ILG ++N+FM G + KIS+P KRA T+ FS +AV+S R G+LCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S ++ + I KL+++ T EGE I L Q +++ D G++ LF +SPL I H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLT-LEDGF 314
PF+ + L + DFE+VV L+G VE+T TCQ R+SY+ +EVLWG+RF +++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 315 YEVDYASFHETFEVPTPSCS 334
Y VD+ +F +T EV TP C+
Sbjct: 318 YRVDFHNFSKTVEVETPHCA 337
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 306 bits (785), Expect = 2e-83
Identities = 149/320 (46%), Positives = 216/320 (67%), Gaps = 4/320 (1%)
Query: 19 RGRQRYVEKDGRCNVQQGNVRETYRYL--TDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
R R R V KDGRCN++ GNV R++ D++TT++DL+WR + F+ A+ +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
+W+ +AY DL +A TPCV N+NG +AFLFS+ET+ TIGYG R +T+QC
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q+ILG ++N+FM G + KIS+P KRA T+ FS +AV+S R G+LCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S ++ + I KL+++ T EGE I L Q +++ D G++ LF +SPL I H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLT-LEDGF 314
PF+ + L + DFE+VV L+G VE+T TCQ R+SY+ +EVLWG+RF +++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 315 YEVDYASFHETFEVPTPSCS 334
Y VD+ +F +T EV TP C+
Sbjct: 318 YRVDFHNFSKTVEVETPHCA 337
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 286 bits (733), Expect = 2e-77
Identities = 141/323 (43%), Positives = 219/323 (67%), Gaps = 8/323 (2%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
+RR R+R + KDG CNV ++ E Y+ D+FTTLVD +WR + F L+Y L+WL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G+++WLIA+ GDL L D TPCV+N++ F AFLFS+ET+TTIGYG+R +T++C
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+++++LQ+IL ++N F++G K++ KRA T+ FS A++ +RDG+LCLM+R+GD
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R +H+VE ++RA+L+R + EG + + DL + +D++ LV+P+ I HEID S
Sbjct: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHES 261
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + R+A+ +D+FEI+V ++TG + Q+RSSY+ E+LWGHRF VL ++ +Y
Sbjct: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
Query: 316 EVDYASFHETFEVPTPSCSAREL 338
+V+ F + EV P CSA++L
Sbjct: 322 KVNCLQFEGSVEVYAPFCSAKQL 344
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 286 bits (733), Expect = 2e-77
Identities = 141/323 (43%), Positives = 219/323 (67%), Gaps = 8/323 (2%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
+RR R+R + KDG CNV ++ E Y+ D+FTTLVD +WR + F L+Y L+WL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G+++WLIA+ GDL L D TPCV+N++ F AFLFS+ET+TTIGYG+R +T++C
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+++++LQ+IL ++N F++G K++ KRA T+ FS A++ +RDG+LCLM+R+GD
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R +H+VE ++RA+L+R + EG + + DL + +D++ LV+P+ I HEID S
Sbjct: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHES 261
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + R+A+ +D+FEI+V ++TG + Q+RSSY+ E+LWGHRF VL ++ +Y
Sbjct: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
Query: 316 EVDYASFHETFEVPTPSCSAREL 338
+V+ F + EV P CSA++L
Sbjct: 322 KVNCLQFEGSVEVYAPFCSAKQL 344
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 286 bits (733), Expect = 2e-77
Identities = 141/323 (43%), Positives = 219/323 (67%), Gaps = 8/323 (2%)
Query: 17 RRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
+RR R+R + KDG CNV ++ E Y+ D+FTTLVD +WR + F L+Y L+WL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
G+++WLIA+ GDL L D TPCV+N++ F AFLFS+ET+TTIGYG+R +T++C
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
+++++LQ+IL ++N F++G K++ KRA T+ FS A++ +RDG+LCLM+R+GD
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R +H+VE ++RA+L+R + EG + + DL + +D++ LV+P+ I HEID S
Sbjct: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHES 261
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
P + R+A+ +D+FEI+V ++TG + Q+RSSY+ E+LWGHRF VL ++ +Y
Sbjct: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
Query: 316 EVDYASFHETFEVPTPSCSAREL 338
+V+ F + EV P CSA++L
Sbjct: 322 KVNCLQFEGSVEVYAPFCSAKQL 344
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 273 bits (698), Expect = 2e-73
Identities = 144/349 (41%), Positives = 215/349 (61%), Gaps = 8/349 (2%)
Query: 21 RQRYVEKDGRCNVQQGNVRET-YRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIW 79
R+R + KDGR NV+ ++ + + YL DL+TT +D+QWR LL F +A TW FG +W
Sbjct: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
Query: 80 WLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVL 138
+L+A GDL L+ A TPCV ++ AFLFS+E++TTIGYG R I+++CP IVL
Sbjct: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
Query: 139 LLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSS 198
L+ Q +L +++ F+ G KI++P KRA T+ FS HAVV+ +G+ CLM RV ++R S
Sbjct: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
Query: 199 HIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFW 258
++ + KL+++ QT EGE I L+Q +++ DT D FL+ PL H +D SP
Sbjct: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLK 266
Query: 259 EASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLE-DGFYEV 317
+ R+ E DFE+V+IL G VE+T TCQ R+SYL +E+LWG+ FT ++L G Y
Sbjct: 267 DLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIA 325
Query: 318 DYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGA 366
D++ F + +V +PS L ++ R + L E+ E+EG+
Sbjct: 326 DFSLFDQVVKVASPS----GLRDSTVRYGDPEKLKLEESLREQAEKEGS 370
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 238 bits (608), Expect = 5e-63
Identities = 117/315 (37%), Positives = 193/315 (61%), Gaps = 3/315 (0%)
Query: 18 RRGRQRYVEKDGRCNVQQGNVRETYR-YLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
+ R R + K G NV+ V Y YL DL+TT++D++WR L F + +TW FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
I++ IA+ GDLE E + TPC+ ++ AFLFS+E++TTIGYG R IT++CP
Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q ++ +++ F+ G KI++P KRA T+ FS AV++ ++G+LCL+ +V ++
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S +++ + KL+++ T EGE I L+Q + D+ + FL+ P+ H +D S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGF 314
P + + + L+ +FE+VV+L VE+T CQ+R+SY+ +E+ WG F V++L ++G
Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
Query: 315 YEVDYASFHETFEVP 329
Y D++ F + + P
Sbjct: 323 YVADFSQFEQIRKSP 337
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 238 bits (608), Expect = 5e-63
Identities = 117/315 (37%), Positives = 193/315 (61%), Gaps = 3/315 (0%)
Query: 18 RRGRQRYVEKDGRCNVQQGNVRETYR-YLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
+ R R + K G NV+ V Y YL DL+TT++D++WR L F + +TW FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
I++ IA+ GDLE E + TPC+ ++ AFLFS+E++TTIGYG R IT++CP
Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q ++ +++ F+ G KI++P KRA T+ FS AV++ ++G+LCL+ +V ++
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S +++ + KL+++ T EGE I L+Q + D+ + FL+ P+ H +D S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGF 314
P + + + L+ +FE+VV+L VE+T CQ+R+SY+ +E+ WG F V++L ++G
Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
Query: 315 YEVDYASFHETFEVP 329
Y D++ F + + P
Sbjct: 323 YVADFSQFEQIRKSP 337
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 238 bits (608), Expect = 5e-63
Identities = 117/315 (37%), Positives = 193/315 (61%), Gaps = 3/315 (0%)
Query: 18 RRGRQRYVEKDGRCNVQQGNVRETYR-YLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
+ R R + K G NV+ V Y YL DL+TT++D++WR L F + +TW FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
I++ IA+ GDLE E + TPC+ ++ AFLFS+E++TTIGYG R IT++CP
Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
Query: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
I LL+ Q ++ +++ F+ G KI++P KRA T+ FS AV++ ++G+LCL+ +V ++
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
Query: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
R S +++ + KL+++ T EGE I L+Q + D+ + FL+ P+ H +D S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
Query: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGF 314
P + + + L+ +FE+VV+L VE+T CQ+R+SY+ +E+ WG F V++L ++G
Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
Query: 315 YEVDYASFHETFEVP 329
Y D++ F + + P
Sbjct: 323 YVADFSQFEQIRKSP 337
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 187 bits (474), Expect = 2e-47
Identities = 114/320 (35%), Positives = 168/320 (52%), Gaps = 13/320 (4%)
Query: 22 QRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWL 81
+R V KDG +Q + YL D + L+D++WR +L F ++ + WL F +W++
Sbjct: 18 RRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
Query: 82 IAYGRGDLEHLEDTA---WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVL 138
+A GDLE D T CV + F AAF FS+ET+ TIGYG + CP I L
Sbjct: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
Query: 139 LLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSS 198
L +Q +LG M+ AF+ G KI++P RA ++ F+ AVV+ DG+ L+F+V + R S
Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
Query: 199 HIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFD--TGDDRLFLVSPLVISHEIDAASP 256
+ + A L + R+ + L+QT + D + D+ F + PL H I +SP
Sbjct: 198 PLTSVRVSAVLYQERENGK-----LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
Query: 257 FWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGFY 315
+ FE+VV L M E TG CQ R+SYL E++ H F S+LT G Y
Sbjct: 253 LATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
Query: 316 EVDYASFHETF-EVPTPSCS 334
++ +F +T E PTP S
Sbjct: 312 QIKMENFDKTVPEFPTPLVS 331
>gi|6912446 potassium voltage-gated channel, subfamily H, member 4
[Homo sapiens]
Length = 1017
Score = 31.6 bits (70), Expect = 1.3
Identities = 26/117 (22%), Positives = 52/117 (44%), Gaps = 26/117 (22%)
Query: 59 LSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAW-------------TPCVNNLN 105
L+LL V A W+ IW++I GR ++E + W P VN
Sbjct: 362 LTLLMSVFALLAHWM--ACIWYVI--GRREMEANDPLLWDIGWLHELGKRLEVPYVNGSV 417
Query: 106 G-------FVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVG 155
G ++AA F++ + T++G+G+ + + + ++G++++A + G
Sbjct: 418 GGPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEK--IFSICTMLIGALMHAVVFG 472
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,160,436
Number of Sequences: 37866
Number of extensions: 644401
Number of successful extensions: 2216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2112
Number of HSP's gapped (non-prelim): 51
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.