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Search of human proteins with 25121966
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
(379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 750 0.0
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 445 e-125
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 445 e-125
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 445 e-125
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 355 5e-98
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 355 5e-98
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 355 5e-98
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 355 5e-98
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 355 5e-98
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 282 3e-76
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 279 3e-75
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 273 2e-73
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 273 2e-73
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 270 1e-72
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 270 1e-72
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 270 1e-72
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 269 4e-72
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 268 8e-72
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 268 8e-72
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 268 8e-72
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 263 1e-70
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 263 1e-70
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 263 1e-70
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 258 8e-69
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 255 4e-68
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 244 9e-65
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 226 3e-59
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 226 3e-59
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 226 3e-59
gi|148728188 integrin, alpha E precursor [Homo sapiens] 33 0.42
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 750 bits (1936), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 1 MTSVAKVYYSQTTQTESRPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFI 60
MTSVAKVYYSQTTQTESRPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFI
Sbjct: 1 MTSVAKVYYSQTTQTESRPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFI 60
Query: 61 DMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFL 120
DMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFL
Sbjct: 61 DMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFL 120
Query: 121 FSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIR 180
FSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIR
Sbjct: 121 FSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIR 180
Query: 181 FSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQV 240
FSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQV
Sbjct: 181 FSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQV 240
Query: 241 DTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSY 300
DTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSY
Sbjct: 241 DTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSY 300
Query: 301 LPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEES 360
LPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEES
Sbjct: 301 LPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEES 360
Query: 361 LREQAEKEGSALSVRISNV 379
LREQAEKEGSALSVRISNV
Sbjct: 361 LREQAEKEGSALSVRISNV 379
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 445 bits (1144), Expect = e-125
Identities = 231/363 (63%), Positives = 283/363 (77%), Gaps = 11/363 (3%)
Query: 22 GPGIR--RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTW 79
G G++ R RV++K G SNVR++ + LYL+DLWTT IDM+WRYKL LF+ATF TW
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTW 78
Query: 80 FLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEE 139
FLFGV++Y +A HGDL +P +NHTPC+++V +LTGAFLFSLESQTTIGYG R I+EE
Sbjct: 79 FLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEE 138
Query: 140 CPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIR 199
CP AI LL+AQLV+TT++EIFITGTFLAKIARPKKRAETI+FS AV+ NGK CL+I+
Sbjct: 139 CPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQ 198
Query: 200 VANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVV 259
VANMRKSLLI CQ++GKLLQTH TKEGE I LNQ V F VD++S+SPFLILP+TFYHV+
Sbjct: 199 VANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVL 258
Query: 260 DETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS 318
DETSPL+DL P E +FELV++L+ TVESTSA CQ RTSY+PEEI WG+EF P +SLS
Sbjct: 259 DETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS 318
Query: 319 ASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLR--EQAEKEGSALSVRI 376
+GKY+ADFS F+Q+ K SP D T D EK +LEE R +Q E+E L ++
Sbjct: 319 KNGKYVADFSQFEQIRK--SP----DCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQ 372
Query: 377 SNV 379
SNV
Sbjct: 373 SNV 375
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 445 bits (1144), Expect = e-125
Identities = 231/363 (63%), Positives = 283/363 (77%), Gaps = 11/363 (3%)
Query: 22 GPGIR--RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTW 79
G G++ R RV++K G SNVR++ + LYL+DLWTT IDM+WRYKL LF+ATF TW
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTW 78
Query: 80 FLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEE 139
FLFGV++Y +A HGDL +P +NHTPC+++V +LTGAFLFSLESQTTIGYG R I+EE
Sbjct: 79 FLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEE 138
Query: 140 CPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIR 199
CP AI LL+AQLV+TT++EIFITGTFLAKIARPKKRAETI+FS AV+ NGK CL+I+
Sbjct: 139 CPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQ 198
Query: 200 VANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVV 259
VANMRKSLLI CQ++GKLLQTH TKEGE I LNQ V F VD++S+SPFLILP+TFYHV+
Sbjct: 199 VANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVL 258
Query: 260 DETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS 318
DETSPL+DL P E +FELV++L+ TVESTSA CQ RTSY+PEEI WG+EF P +SLS
Sbjct: 259 DETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS 318
Query: 319 ASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLR--EQAEKEGSALSVRI 376
+GKY+ADFS F+Q+ K SP D T D EK +LEE R +Q E+E L ++
Sbjct: 319 KNGKYVADFSQFEQIRK--SP----DCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQ 372
Query: 377 SNV 379
SNV
Sbjct: 373 SNV 375
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 445 bits (1144), Expect = e-125
Identities = 231/363 (63%), Positives = 283/363 (77%), Gaps = 11/363 (3%)
Query: 22 GPGIR--RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTW 79
G G++ R RV++K G SNVR++ + LYL+DLWTT IDM+WRYKL LF+ATF TW
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTW 78
Query: 80 FLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEE 139
FLFGV++Y +A HGDL +P +NHTPC+++V +LTGAFLFSLESQTTIGYG R I+EE
Sbjct: 79 FLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEE 138
Query: 140 CPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIR 199
CP AI LL+AQLV+TT++EIFITGTFLAKIARPKKRAETI+FS AV+ NGK CL+I+
Sbjct: 139 CPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQ 198
Query: 200 VANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVV 259
VANMRKSLLI CQ++GKLLQTH TKEGE I LNQ V F VD++S+SPFLILP+TFYHV+
Sbjct: 199 VANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVL 258
Query: 260 DETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS 318
DETSPL+DL P E +FELV++L+ TVESTSA CQ RTSY+PEEI WG+EF P +SLS
Sbjct: 259 DETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS 318
Query: 319 ASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLR--EQAEKEGSALSVRI 376
+GKY+ADFS F+Q+ K SP D T D EK +LEE R +Q E+E L ++
Sbjct: 319 KNGKYVADFSQFEQIRK--SP----DCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQ 372
Query: 377 SNV 379
SNV
Sbjct: 373 SNV 375
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 355 bits (910), Expect = 5e-98
Identities = 172/320 (53%), Positives = 227/320 (70%), Gaps = 2/320 (0%)
Query: 22 GPGIRRRRVLTKDGRSNVRMEHI-ADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWF 80
G +R R+++KDGR N+ ++ A RF++ D+WTT +D++WRYK+ +F F G+WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 81 LFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEEC 140
FG++WY VA H DL E P ANHTPCV ++ LT AFLFSLE+Q TIGYGFR ++E+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 141 PLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRV 200
AI LLI Q +L I+ F+ G LAKI+RPKKRA+TI FS++AV++ GK CL+IRV
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 201 ANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVD 260
AN+RKSLLIG + GKLL+T T EGE I L+Q+N+ F VD +++ F I PLT YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 261 ETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSA 319
SP + + + DFELV+ L GTVESTSATCQVRTSY+PEE+LWGY F P +S +
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 SGKYIADFSLFDQVVKVASP 339
GKY DF F + V+V +P
Sbjct: 315 EGKYRVDFHNFSKTVEVETP 334
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 355 bits (910), Expect = 5e-98
Identities = 172/320 (53%), Positives = 227/320 (70%), Gaps = 2/320 (0%)
Query: 22 GPGIRRRRVLTKDGRSNVRMEHI-ADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWF 80
G +R R+++KDGR N+ ++ A RF++ D+WTT +D++WRYK+ +F F G+WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 81 LFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEEC 140
FG++WY VA H DL E P ANHTPCV ++ LT AFLFSLE+Q TIGYGFR ++E+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 141 PLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRV 200
AI LLI Q +L I+ F+ G LAKI+RPKKRA+TI FS++AV++ GK CL+IRV
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 201 ANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVD 260
AN+RKSLLIG + GKLL+T T EGE I L+Q+N+ F VD +++ F I PLT YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 261 ETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSA 319
SP + + + DFELV+ L GTVESTSATCQVRTSY+PEE+LWGY F P +S +
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 SGKYIADFSLFDQVVKVASP 339
GKY DF F + V+V +P
Sbjct: 315 EGKYRVDFHNFSKTVEVETP 334
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 355 bits (910), Expect = 5e-98
Identities = 172/320 (53%), Positives = 227/320 (70%), Gaps = 2/320 (0%)
Query: 22 GPGIRRRRVLTKDGRSNVRMEHI-ADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWF 80
G +R R+++KDGR N+ ++ A RF++ D+WTT +D++WRYK+ +F F G+WF
Sbjct: 34 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 93
Query: 81 LFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEEC 140
FG++WY VA H DL E P ANHTPCV ++ LT AFLFSLE+Q TIGYGFR ++E+C
Sbjct: 94 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 153
Query: 141 PLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRV 200
AI LLI Q +L I+ F+ G LAKI+RPKKRA+TI FS++AV++ GK CL+IRV
Sbjct: 154 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 213
Query: 201 ANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVD 260
AN+RKSLLIG + GKLL+T T EGE I L+Q+N+ F VD +++ F I PLT YHV+D
Sbjct: 214 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 273
Query: 261 ETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSA 319
SP + + + DFELV+ L GTVESTSATCQVRTSY+PEE+LWGY F P +S +
Sbjct: 274 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 333
Query: 320 SGKYIADFSLFDQVVKVASP 339
GKY DF F + V+V +P
Sbjct: 334 EGKYRVDFHNFSKTVEVETP 353
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 355 bits (910), Expect = 5e-98
Identities = 172/320 (53%), Positives = 227/320 (70%), Gaps = 2/320 (0%)
Query: 22 GPGIRRRRVLTKDGRSNVRMEHI-ADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWF 80
G +R R+++KDGR N+ ++ A RF++ D+WTT +D++WRYK+ +F F G+WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 81 LFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEEC 140
FG++WY VA H DL E P ANHTPCV ++ LT AFLFSLE+Q TIGYGFR ++E+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 141 PLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRV 200
AI LLI Q +L I+ F+ G LAKI+RPKKRA+TI FS++AV++ GK CL+IRV
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 201 ANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVD 260
AN+RKSLLIG + GKLL+T T EGE I L+Q+N+ F VD +++ F I PLT YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 261 ETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSA 319
SP + + + DFELV+ L GTVESTSATCQVRTSY+PEE+LWGY F P +S +
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 SGKYIADFSLFDQVVKVASP 339
GKY DF F + V+V +P
Sbjct: 315 EGKYRVDFHNFSKTVEVETP 334
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 355 bits (910), Expect = 5e-98
Identities = 172/320 (53%), Positives = 227/320 (70%), Gaps = 2/320 (0%)
Query: 22 GPGIRRRRVLTKDGRSNVRMEHI-ADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWF 80
G +R R+++KDGR N+ ++ A RF++ D+WTT +D++WRYK+ +F F G+WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 81 LFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEEC 140
FG++WY VA H DL E P ANHTPCV ++ LT AFLFSLE+Q TIGYGFR ++E+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 141 PLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRV 200
AI LLI Q +L I+ F+ G LAKI+RPKKRA+TI FS++AV++ GK CL+IRV
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 201 ANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVD 260
AN+RKSLLIG + GKLL+T T EGE I L+Q+N+ F VD +++ F I PLT YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 261 ETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSA 319
SP + + + DFELV+ L GTVESTSATCQVRTSY+PEE+LWGY F P +S +
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 SGKYIADFSLFDQVVKVASP 339
GKY DF F + V+V +P
Sbjct: 315 EGKYRVDFHNFSKTVEVETP 334
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 282 bits (722), Expect = 3e-76
Identities = 141/313 (45%), Positives = 209/313 (66%), Gaps = 3/313 (0%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
R R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LFG+++
Sbjct: 43 RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102
Query: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
+++AVAHGDL E TPCV+QVH AFLFS+E+QTTIGYG R ++EECP+A+ +
Sbjct: 103 WVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
Query: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
++AQ ++ I++ F+ G +AK+ARPKKRA+T+ FS +AVVA +GK CLM RV N+RKS
Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
Query: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLK 266
++ V +L++ T+EGE I L+Q+++ D D FL+ P+T H +DE SPL
Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
Query: 267 DLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIA 325
+ + E DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P + +Y
Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVL-FEEKNQYKI 340
Query: 326 DFSLFDQVVKVAS 338
D+S F + +V S
Sbjct: 341 DYSHFHKTYEVPS 353
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 279 bits (714), Expect = 3e-75
Identities = 142/315 (45%), Positives = 209/315 (66%), Gaps = 7/315 (2%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
R R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LFGV++
Sbjct: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
Query: 87 YLVAVAHGDLLELDPPANH--TPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAI 144
+++AVAHGDL +P H TPCV+QVH AFLFS+E+QTTIGYG R ++EEC +A+
Sbjct: 103 WVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
Query: 145 VLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMR 204
+++AQ ++ I++ F+ G +AK+ARPKKRA T+ FS +AVVA +GK CLM RV N+R
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
Query: 205 KSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSP 264
KS ++ V +L++ T+EGE I L+Q+++ D D FL+ P+T H +DE SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
Query: 265 LKDLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKY 323
L + + E DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P + +Y
Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVL-FEEKNQY 338
Query: 324 IADFSLFDQVVKVAS 338
D+S F + +V S
Sbjct: 339 KIDYSHFHKTYEVPS 353
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 273 bits (698), Expect = 2e-73
Identities = 144/349 (41%), Positives = 215/349 (61%), Gaps = 8/349 (2%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
R+R + KDGR NV+ ++ + + YL DL+TT +D+QWR LL F +A TW FG +W
Sbjct: 21 RQRYVEKDGRCNVQQGNVRET-YRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIW 79
Query: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
+L+A GDL L+ A TPCV ++ AFLFS+E++TTIGYG R I+++CP IVL
Sbjct: 80 WLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVL 138
Query: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
L+ Q +L +++ F+ G KI++P KRA T+ FS HAVV+ +G+ CLM RV ++R S
Sbjct: 139 LLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSS 198
Query: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLK 266
++ + KL+++ QT EGE I L+Q +++ DT D FL+ PL H +D SP
Sbjct: 199 HIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFW 258
Query: 267 DLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIA 325
+ R+ E DFE+V+IL G VE+T TCQ R+SYL +E+LWG+ FT ++L G Y
Sbjct: 259 EASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLE-DGFYEV 317
Query: 326 DFSLFDQVVKVASPS----GLRDSTVRYGDPEKLKLEESLREQAEKEGS 370
D++ F + +V +PS L ++ R + L E+ E+EG+
Sbjct: 318 DYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGA 366
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 273 bits (697), Expect = 2e-73
Identities = 134/318 (42%), Positives = 203/318 (63%), Gaps = 3/318 (0%)
Query: 23 PGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82
P +R+R + K+GR NV+ ++ + YL DL+TT +D++WR+ L +F T+ W
Sbjct: 39 PKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
Query: 83 GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
+W+++A GDL + N+TPCV V+ AFLF +E++ TIGYG+RYI+++CP
Sbjct: 99 ASMWWVIAYTRGDLNKAHV-GNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
Query: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
I+L + Q +L +I++ F+ G K+++PKKRAET+ FS+HAV++ +GK LM RV N
Sbjct: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
Query: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262
+R S ++ Q+ KLL++ QT EGE + L+Q+ + T +D FL+ PLT HV+D
Sbjct: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
Query: 263 SPLKDLPLRSGEGD-FELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321
SP DL RS + + FE+V+IL G VE+T TCQ RTSY +E+LWG+ F P ISL G
Sbjct: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLE-EG 336
Query: 322 KYIADFSLFDQVVKVASP 339
+ D+S F +V +P
Sbjct: 337 FFKVDYSQFHATFEVPTP 354
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 270 bits (691), Expect = 1e-72
Identities = 139/317 (43%), Positives = 205/317 (64%), Gaps = 7/317 (2%)
Query: 26 RRR---RVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82
RRR R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LF
Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 83 GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
GV+++++AVAHGDL E TPCV+QVH AFLFS+++Q TI YG R ++EECP+
Sbjct: 99 GVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPV 157
Query: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
A+ +++AQ ++ I+ F+ G +AK+ RPKKRA+T+ FS +AVVA +GK C M RV N
Sbjct: 158 AVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGN 217
Query: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262
+RKS ++ V +L++ TKEGE I L+Q+++ D D FL+ P+T H +DE
Sbjct: 218 LRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEA 277
Query: 263 SPLKDLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321
SPL + + + DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P L
Sbjct: 278 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKN 335
Query: 322 KYIADFSLFDQVVKVAS 338
+Y D+ F + +V S
Sbjct: 336 QYKIDYLHFHKTYEVPS 352
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 270 bits (691), Expect = 1e-72
Identities = 139/317 (43%), Positives = 205/317 (64%), Gaps = 7/317 (2%)
Query: 26 RRR---RVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82
RRR R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LF
Sbjct: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
Query: 83 GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
GV+++++AVAHGDL E TPCV+QVH AFLFS+++Q TI YG R ++EECP+
Sbjct: 201 GVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPV 259
Query: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
A+ +++AQ ++ I+ F+ G +AK+ RPKKRA+T+ FS +AVVA +GK C M RV N
Sbjct: 260 AVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGN 319
Query: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262
+RKS ++ V +L++ TKEGE I L+Q+++ D D FL+ P+T H +DE
Sbjct: 320 LRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEA 379
Query: 263 SPLKDLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321
SPL + + + DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P L
Sbjct: 380 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKN 437
Query: 322 KYIADFSLFDQVVKVAS 338
+Y D+ F + +V S
Sbjct: 438 QYKIDYLHFHKTYEVPS 454
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 270 bits (691), Expect = 1e-72
Identities = 139/317 (43%), Positives = 205/317 (64%), Gaps = 7/317 (2%)
Query: 26 RRR---RVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82
RRR R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LF
Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 83 GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
GV+++++AVAHGDL E TPCV+QVH AFLFS+++Q TI YG R ++EECP+
Sbjct: 99 GVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPV 157
Query: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
A+ +++AQ ++ I+ F+ G +AK+ RPKKRA+T+ FS +AVVA +GK C M RV N
Sbjct: 158 AVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGN 217
Query: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262
+RKS ++ V +L++ TKEGE I L+Q+++ D D FL+ P+T H +DE
Sbjct: 218 LRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEA 277
Query: 263 SPLKDLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321
SPL + + + DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P L
Sbjct: 278 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKN 335
Query: 322 KYIADFSLFDQVVKVAS 338
+Y D+ F + +V S
Sbjct: 336 QYKIDYLHFHKTYEVPS 352
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 269 bits (687), Expect = 4e-72
Identities = 136/346 (39%), Positives = 214/346 (61%), Gaps = 8/346 (2%)
Query: 28 RRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWY 87
+R + KDG+ NV ++ + + YL D++TT +D++WR+ LL+F + TW FG++W+
Sbjct: 54 QRYVRKDGKCNVHHGNVRET-YRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWW 112
Query: 88 LVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLL 147
L+A GD+ ++ P+ TPCV ++ AFLFS+E++TTIGYG+R I+++CP I+LL
Sbjct: 113 LIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILL 171
Query: 148 IAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSL 207
+ Q VL +I+ F+ G KI++PKKRAET+ FS HAV++ +GK CLM RV ++R S
Sbjct: 172 LIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSH 231
Query: 208 LIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKD 267
++ + KL+++ QT EGE I LNQ ++ T D FL+ PL H +++ SP +
Sbjct: 232 IVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWE 291
Query: 268 L-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIAD 326
+ + + + E+V+IL G VE+T TCQ R+SY+ EILWGY FTP ++L G Y D
Sbjct: 292 ISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLE-DGFYEVD 350
Query: 327 FSLFDQVVKVASPS----GLRDSTVRYGDPEKLKLEESLREQAEKE 368
++ F + + ++PS L + R P + L + AE E
Sbjct: 351 YNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELE 396
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 268 bits (684), Expect = 8e-72
Identities = 135/311 (43%), Positives = 202/311 (64%), Gaps = 5/311 (1%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
R R + KDG NV+ ++ +K YL D++TT +D++WR+ L++F F +W FG V+
Sbjct: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
Query: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
+L+A+ HGDL D CV +V++ T AFLFS+E+QTTIGYGFR +++ECP+A+ +
Sbjct: 104 WLIALLHGDL---DASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
Query: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
++ Q ++ I++ FI G +AK+A+PKKR ET+ FS +AV+A +GK CLM RV N+RKS
Sbjct: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
Query: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLK 266
L+ V +LL++ T EGE I L+Q+++ D+ D FL+ P+T H +DE SPL
Sbjct: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
Query: 267 DLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIA 325
DL + DFE+V+IL G VE+T+ T Q R+SYL EILWG+ + P + Y
Sbjct: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVL-FEEKHYYKV 339
Query: 326 DFSLFDQVVKV 336
D+S F + +V
Sbjct: 340 DYSRFHKTYEV 350
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 268 bits (684), Expect = 8e-72
Identities = 136/329 (41%), Positives = 206/329 (62%), Gaps = 19/329 (5%)
Query: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
RR R + K+G+ NV ++++K Y+ D++TT +D +WRY L++FSA F +W FG++
Sbjct: 17 RRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLL 76
Query: 86 WYLVAVAHGDLLELDP----------------PANHTPCVVQVHTLTGAFLFSLESQTTI 129
++ +A HGDL E P P PC++ V+ GAFLFS+E+QTTI
Sbjct: 77 FWCIAFFHGDL-EASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTI 135
Query: 130 GYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVAS 189
GYGFR ++EECPLA++ ++ Q ++ +++ F+ GT +AK+ARPKKRA+T+ FS HAV++
Sbjct: 136 GYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISV 195
Query: 190 HNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFL 249
+GK CLM RV N+RKS ++ V +L++ + T+EGE + L+Q ++ D D FL
Sbjct: 196 RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFL 255
Query: 250 ILPLTFYHVVDETSPLKDLPLRSGEG-DFELVLILSGTVESTSATCQVRTSYLPEEILWG 308
+ P+ H +DE SPL + E DFE+V+IL G VE+T+ T Q R+SYL EILWG
Sbjct: 256 VSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWG 315
Query: 309 YEFTPAISLSASGKYIADFSLFDQVVKVA 337
+ F P + Y D+S F + +VA
Sbjct: 316 HRFEPVV-FEEKSHYKVDYSRFHKTYEVA 343
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 268 bits (684), Expect = 8e-72
Identities = 136/329 (41%), Positives = 206/329 (62%), Gaps = 19/329 (5%)
Query: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
RR R + K+G+ NV ++++K Y+ D++TT +D +WRY L++FSA F +W FG++
Sbjct: 17 RRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLL 76
Query: 86 WYLVAVAHGDLLELDP----------------PANHTPCVVQVHTLTGAFLFSLESQTTI 129
++ +A HGDL E P P PC++ V+ GAFLFS+E+QTTI
Sbjct: 77 FWCIAFFHGDL-EASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTI 135
Query: 130 GYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVAS 189
GYGFR ++EECPLA++ ++ Q ++ +++ F+ GT +AK+ARPKKRA+T+ FS HAV++
Sbjct: 136 GYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISV 195
Query: 190 HNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFL 249
+GK CLM RV N+RKS ++ V +L++ + T+EGE + L+Q ++ D D FL
Sbjct: 196 RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFL 255
Query: 250 ILPLTFYHVVDETSPLKDLPLRSGEG-DFELVLILSGTVESTSATCQVRTSYLPEEILWG 308
+ P+ H +DE SPL + E DFE+V+IL G VE+T+ T Q R+SYL EILWG
Sbjct: 256 VSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWG 315
Query: 309 YEFTPAISLSASGKYIADFSLFDQVVKVA 337
+ F P + Y D+S F + +VA
Sbjct: 316 HRFEPVV-FEEKSHYKVDYSRFHKTYEVA 343
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 263 bits (673), Expect = 1e-70
Identities = 132/328 (40%), Positives = 205/328 (62%), Gaps = 5/328 (1%)
Query: 15 TESRPLMGPGIR-RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSA 73
T+ L+ G + R+R + K G+ NV ++ + + YL DL+TT +D++WR+ LL+F+
Sbjct: 37 TDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQET-YRYLSDLFTTLVDLKWRFNLLVFTM 95
Query: 74 TFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGF 133
+ TW FG +W+L+A GDL + PCV + AFLFS+E++TTIGYGF
Sbjct: 96 VYTVTWLFFGFIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGF 154
Query: 134 RYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGK 193
R I+E+CP I+LL+ Q +L +I+ F+ G KI++PKKRAET+ FS +AV++ + K
Sbjct: 155 RVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEK 214
Query: 194 PCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPL 253
CLM RV ++R S ++ + KL+++ QTKEGE I LNQ ++ DT D FL+ PL
Sbjct: 215 LCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPL 274
Query: 254 TFYHVVDETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFT 312
H +++ SP ++ + + +FE+V+IL G VE+T TCQ R+SY+ E+LWG+ FT
Sbjct: 275 IISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFT 334
Query: 313 PAISLSASGKYIADFSLFDQVVKVASPS 340
P ++L G Y D++ F + +PS
Sbjct: 335 PVLTLE-KGFYEVDYNTFHDTYETNTPS 361
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 263 bits (673), Expect = 1e-70
Identities = 139/320 (43%), Positives = 198/320 (61%), Gaps = 6/320 (1%)
Query: 19 PLMGP-GIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAG 77
P+ P G RR R + KDG NVR ++ + YL DL+TT +D++WR+ LLFS +F
Sbjct: 40 PVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLA 99
Query: 78 TWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYIS 137
+W LFG+ ++L+A HGDL PPA PC V + AFLF+LE+QT+IGYG R ++
Sbjct: 100 SWLLFGLAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVT 156
Query: 138 EECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLM 197
EECP A+ ++ Q + +L+ F+ G +AK+A+PKKR ET+ FS++AVVA + + CLM
Sbjct: 157 EECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLM 216
Query: 198 IRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYH 257
RV N+R+S L+ V +LLQ T EGE I L+ +V D +D FL+ P+T H
Sbjct: 217 WRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVH 276
Query: 258 VVDETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAIS 316
+D SPL +L DFELV+IL G VE+T+ T Q R+SYLP E+LWG+ F P +
Sbjct: 277 EIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL- 335
Query: 317 LSASGKYIADFSLFDQVVKV 336
+Y D+ F + +V
Sbjct: 336 FQRGSQYEVDYRHFHRTYEV 355
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 263 bits (673), Expect = 1e-70
Identities = 139/320 (43%), Positives = 198/320 (61%), Gaps = 6/320 (1%)
Query: 19 PLMGP-GIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAG 77
P+ P G RR R + KDG NVR ++ + YL DL+TT +D++WR+ LLFS +F
Sbjct: 40 PVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLA 99
Query: 78 TWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYIS 137
+W LFG+ ++L+A HGDL PPA PC V + AFLF+LE+QT+IGYG R ++
Sbjct: 100 SWLLFGLAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVT 156
Query: 138 EECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLM 197
EECP A+ ++ Q + +L+ F+ G +AK+A+PKKR ET+ FS++AVVA + + CLM
Sbjct: 157 EECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLM 216
Query: 198 IRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYH 257
RV N+R+S L+ V +LLQ T EGE I L+ +V D +D FL+ P+T H
Sbjct: 217 WRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVH 276
Query: 258 VVDETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAIS 316
+D SPL +L DFELV+IL G VE+T+ T Q R+SYLP E+LWG+ F P +
Sbjct: 277 EIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL- 335
Query: 317 LSASGKYIADFSLFDQVVKV 336
+Y D+ F + +V
Sbjct: 336 FQRGSQYEVDYRHFHRTYEV 355
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 258 bits (658), Expect = 8e-69
Identities = 129/316 (40%), Positives = 201/316 (63%), Gaps = 6/316 (1%)
Query: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
RR R ++K G NV ++I ++ +L+D++TT +D++W + LL+F+ +F +W LF +
Sbjct: 31 RRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMA 89
Query: 86 WYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIV 145
W+L+A AHGDL + A PCV +H+ + AFLFS+E Q TIG+G R ++EECPLAI+
Sbjct: 90 WWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147
Query: 146 LLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRK 205
+LI Q ++ ++ + G K A+ +RAET+ FS+HAV+A +G+ C M+RV ++RK
Sbjct: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207
Query: 206 SLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPL 265
S++I + ++++ + EGE + L+QV++ + +S FL+ PL YHV+D SPL
Sbjct: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267
Query: 266 KDLPLRS--GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKY 323
DL D E+++IL G VE+T T Q RTSYL +EILWG F P ++ G+Y
Sbjct: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDGRY 326
Query: 324 IADFSLFDQVVKVASP 339
D+S F VKV +P
Sbjct: 327 SVDYSKFGNTVKVPTP 342
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 255 bits (652), Expect = 4e-68
Identities = 144/314 (45%), Positives = 195/314 (62%), Gaps = 12/314 (3%)
Query: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
R RR++TKDG S ++M+ A + YL+D W +DM+WR+ +L+FSA+F W +F V+
Sbjct: 16 RYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVL 74
Query: 86 WYLVAVAHGDLLELD---PPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
WY++A +GDL ELD PP NHT CV + + T AF FSLE+Q TIGYG + S +CP
Sbjct: 75 WYVLAEMNGDL-ELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
Query: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
AI LL Q++L +LE FITG F+AKIARPK RA +IRF+ AVVA +GKP L+ +VAN
Sbjct: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
Query: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVD--TASDSPFLILPLTFYHVVD 260
R S L +V+ L Q E EN +L Q +V F +D ++ + PF I PLT+YH +
Sbjct: 194 TRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSIT 248
Query: 261 ETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSAS 320
+SPL L FELV+ LS E T CQ RTSYLP EI+ + F ++ +
Sbjct: 249 PSSPLATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSK 308
Query: 321 GKYIADFSLFDQVV 334
G+Y FD+ V
Sbjct: 309 GEYQIKMENFDKTV 322
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 244 bits (623), Expect = 9e-65
Identities = 128/330 (38%), Positives = 200/330 (60%), Gaps = 10/330 (3%)
Query: 18 RPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAG 77
+P + + + R + K G N+ ++I ++ +L+D++TT +D++WR+ L++F+ +F
Sbjct: 24 KPRIRDRLPKARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLC 82
Query: 78 TWFLFGVVWYLVAVAHGDLLELDPPAN-------HTPCVVQVHTLTGAFLFSLESQTTIG 130
+W LF ++W+LVA AHGD+ + T CV V + T AFLFS+E Q TIG
Sbjct: 83 SWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIG 142
Query: 131 YGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASH 190
+G R ++EECPLAI +LI Q ++ I+ + G K A+ +RAET+ FS+HAV+A
Sbjct: 143 FGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVR 202
Query: 191 NGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLI 250
NGK C M RV ++RKS++I V ++++ T EGE + ++Q+++ S++ FL+
Sbjct: 203 NGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLV 262
Query: 251 LPLTFYHVVDETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGY 309
PL HV+D+ SPL D+ D E+++IL G VE+T T Q RTSY+ EEI WG+
Sbjct: 263 APLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGH 322
Query: 310 EFTPAISLSASGKYIADFSLFDQVVKVASP 339
F +I G Y D+S F VKVA+P
Sbjct: 323 RFV-SIVTEEEGVYSVDYSKFGNTVKVAAP 351
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 226 bits (576), Expect = 3e-59
Identities = 124/315 (39%), Positives = 196/315 (62%), Gaps = 12/315 (3%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
RRR+L KDG NV +HI + Y+ D++TT +D +WR+ ++FS ++ +W +FG V+
Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
+L+A HGDLL DP TPCV VH+ TGAFLFSLE+QTTIGYG+R ++EEC +A+++
Sbjct: 93 WLIAFHHGDLLN-DPDI--TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
Query: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
+I Q +L+ I+ FI G LAK+A +KRA+TIRFS A++ +GK CLM R+ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
Query: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQ-VDTASDSPFLILPLTFYHVVDETSPL 265
++ V +LL+ + EG ++ + F+ + +D L+ P+T H +D SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
Query: 266 KDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYI 324
L ++ + +FE+++ T +ST + Q R+SY+P EILWG+ F + + Y
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
Query: 325 ADFSLFDQVVKVASP 339
+ F+ V+V +P
Sbjct: 323 VNCLQFEGSVEVYAP 337
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 226 bits (576), Expect = 3e-59
Identities = 124/315 (39%), Positives = 196/315 (62%), Gaps = 12/315 (3%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
RRR+L KDG NV +HI + Y+ D++TT +D +WR+ ++FS ++ +W +FG V+
Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
+L+A HGDLL DP TPCV VH+ TGAFLFSLE+QTTIGYG+R ++EEC +A+++
Sbjct: 93 WLIAFHHGDLLN-DPDI--TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
Query: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
+I Q +L+ I+ FI G LAK+A +KRA+TIRFS A++ +GK CLM R+ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
Query: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQ-VDTASDSPFLILPLTFYHVVDETSPL 265
++ V +LL+ + EG ++ + F+ + +D L+ P+T H +D SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
Query: 266 KDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYI 324
L ++ + +FE+++ T +ST + Q R+SY+P EILWG+ F + + Y
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
Query: 325 ADFSLFDQVVKVASP 339
+ F+ V+V +P
Sbjct: 323 VNCLQFEGSVEVYAP 337
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 226 bits (576), Expect = 3e-59
Identities = 124/315 (39%), Positives = 196/315 (62%), Gaps = 12/315 (3%)
Query: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
RRR+L KDG NV +HI + Y+ D++TT +D +WR+ ++FS ++ +W +FG V+
Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
+L+A HGDLL DP TPCV VH+ TGAFLFSLE+QTTIGYG+R ++EEC +A+++
Sbjct: 93 WLIAFHHGDLLN-DPDI--TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
Query: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
+I Q +L+ I+ FI G LAK+A +KRA+TIRFS A++ +GK CLM R+ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
Query: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQ-VDTASDSPFLILPLTFYHVVDETSPL 265
++ V +LL+ + EG ++ + F+ + +D L+ P+T H +D SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
Query: 266 KDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYI 324
L ++ + +FE+++ T +ST + Q R+SY+P EILWG+ F + + Y
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
Query: 325 ADFSLFDQVVKVASP 339
+ F+ V+V +P
Sbjct: 323 VNCLQFEGSVEVYAP 337
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 33.1 bits (74), Expect = 0.42
Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 10/138 (7%)
Query: 163 GTFLAKIARPKKRAETIRFSQ--HAVVASHNGKPCLMIRVANMRK----SLLIGCQVTGK 216
G FL + A AE ++S +AV H K C + +A + + Q G+
Sbjct: 440 GRFLNQTAAAAADAEAAQYSYLGYAVAVLH--KTCSLSYIAGAPRYKHHGAVFELQKEGR 497
Query: 217 LLQTHQTKEGENIR--LNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSGE 274
EGE + +D + FL++ FYHV E + L +
Sbjct: 498 EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQD 557
Query: 275 GDFELVLILSGTVESTSA 292
G F L ILSG T+A
Sbjct: 558 GSFSLARILSGHPGFTNA 575
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,052,140
Number of Sequences: 37866
Number of extensions: 528945
Number of successful extensions: 1188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1101
Number of HSP's gapped (non-prelim): 39
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.