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Search of human proteins with 24797141
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797141 potassium inwardly-rectifying channel J5 [Homo
sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 856 0.0
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 599 e-171
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 521 e-148
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 450 e-126
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 389 e-108
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 389 e-108
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 389 e-108
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 387 e-108
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 383 e-106
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 371 e-103
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 371 e-103
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 371 e-103
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 351 8e-97
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 351 8e-97
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 337 2e-92
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 330 1e-90
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 316 2e-86
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 316 2e-86
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 316 2e-86
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 316 2e-86
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 316 2e-86
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 278 5e-75
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 278 5e-75
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 278 5e-75
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 263 2e-70
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 258 9e-69
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 258 9e-69
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 258 9e-69
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 182 4e-46
gi|31377765 transmembrane protein 87A isoform 1 [Homo sapiens] 32 0.82
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 856 bits (2211), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKC 60
MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKC
Sbjct: 1 MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKC 60
Query: 61 NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDH 120
NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDH
Sbjct: 61 NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDH 120
Query: 121 VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNA 180
VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNA
Sbjct: 121 VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNA 180
Query: 181 FMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIK 240
FMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIK
Sbjct: 181 FMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIK 240
Query: 241 SRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFE 300
SRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFE
Sbjct: 241 SRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFE 300
Query: 301 VVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTP 360
VVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTP
Sbjct: 301 VVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTP 360
Query: 361 SCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV 419
SCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
Sbjct: 361 SCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV 419
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 599 bits (1544), Expect = e-171
Identities = 305/421 (72%), Positives = 345/421 (81%), Gaps = 20/421 (4%)
Query: 1 MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVP--IATDRTRLLAEGKKPRQRYMEKSG 58
+ GDS M+QD+E V PK +PKQARD +P I+ DRT K+ QRY+ K G
Sbjct: 12 LEGDS---MDQDVESPVAIHQPK-LPKQARDDLPRHISRDRT------KRKIQRYVRKDG 61
Query: 59 KCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDL 118
KCNVHHGNV+ETYRYL+D+FTTLVDLKWRFNLL+F MVYTVTWLFFG IWWLIAYIRGD+
Sbjct: 62 KCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDM 121
Query: 119 DHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIV 178
DH+ D W PCV NL+GFVSAFLFSIETETTIGYG+RVIT+KCPEGIILLL+Q++LGSIV
Sbjct: 122 DHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIV 181
Query: 179 NAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKL 238
NAFMVGCMFVKISQPKKRAETL+FS +AVISMRD KLCLMFRVGDLRNSHIVEASIRAKL
Sbjct: 182 NAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKL 241
Query: 239 IKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEE 298
IKS+QT EGEFIPLNQTDINVG+ TGDDRLFLVSPLIISHEINQ+SPFWE+S+AQL +EE
Sbjct: 242 IKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEE 301
Query: 299 FEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETN 358
E+VVILEGMVEATGMTCQARSSY+ +E+LWG+RFTPVLTLE GFYEVDYN+FH+TYET+
Sbjct: 302 LEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETS 361
Query: 359 TPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGS 418
TPS AKELAE+ L L + L+ AE E+E K L E G
Sbjct: 362 TPSLSAKELAELASRAEL--------PLSWSVSSKLNQHAELETEEEEKNLEEQTERNGD 413
Query: 419 V 419
V
Sbjct: 414 V 414
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 521 bits (1342), Expect = e-148
Identities = 258/371 (69%), Positives = 305/371 (82%), Gaps = 14/371 (3%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGF 106
++ RQRY+EK G+CNV GNV+ETYRYL+DLFTTLVDL+WR +LL F + Y +TWLFFG
Sbjct: 18 RRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGA 77
Query: 107 IWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGII 166
IWWLIAY RGDL+H+ D W PCV NL+GFV+AFLFSIETETTIGYG RVIT++CPEGI+
Sbjct: 78 IWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIV 137
Query: 167 LLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRN 226
LLL+QAILGS+VNAFMVGCMFVKISQP KRA TL+FS++AV+S+RD +LCLMFRVGDLR+
Sbjct: 138 LLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRS 197
Query: 227 SHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPF 286
SHIVEASIRAKLI+SRQT EGEFIPL+QTD++VGFDTGDDRLFLVSPL+ISHEI+ SPF
Sbjct: 198 SHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPF 257
Query: 287 WEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEV 346
WE S+ L +++FE+VVILEGMVEATGMTCQARSSY+ EVLWGHRFT VLTLE GFYEV
Sbjct: 258 WEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEV 317
Query: 347 DYNTFHDTYETNTPSCCAKELAE--MKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
DY +FH+T+E TPSC A+ELAE + + L +PS LD + E EE
Sbjct: 318 DYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPS----------RLDEKVE--EEG 365
Query: 405 EPKGLGGSREA 415
+G GG A
Sbjct: 366 AGEGAGGEAGA 376
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 450 bits (1158), Expect = e-126
Identities = 218/327 (66%), Positives = 268/327 (81%), Gaps = 5/327 (1%)
Query: 47 KKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
KK RQR+++K+G+CNV HGN+ ET RYLSDLFTTLVDLKWR+NL +F + YTV WLF
Sbjct: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
Query: 106 FIWWLIAYIRGDLD--HVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163
+WW+IAY RGDL+ HVG+ + PCV N+ F SAFLF IETE TIGYG+R IT+KCPE
Sbjct: 100 SMWWVIAYTRGDLNKAHVGN--YTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
Query: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223
GIIL L Q+ILGSIV+AF++GCMF+K+SQPKKRAETLMFS +AVISMRD KL LMFRVG+
Sbjct: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
Query: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283
LRNSH+V A IR KL+KSRQT EGEF+PL+Q +++VGF TG D+LFLVSPL I H I+ K
Sbjct: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
Query: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGF 343
SPF+++SQ + E+FE+VVILEG+VE TGMTCQAR+SY + EVLWGHRF PV++LE+GF
Sbjct: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGF 337
Query: 344 YEVDYNTFHDTYETNTPSCCAKELAEM 370
++VDY+ FH T+E TP KE EM
Sbjct: 338 FKVDYSQFHATFEVPTPPYSVKEQEEM 364
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 389 bits (1000), Expect = e-108
Identities = 191/389 (49%), Positives = 275/389 (70%), Gaps = 21/389 (5%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQ-ETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+K R R+++K+G+CNV+ N+ ++ RY++D+FTT VD +WR+ L++F+ + V+WLFFG
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 106 FIWWLIAYIRGDLD----------------HVGDQEWIPCVENLSGFVSAFLFSIETETT 149
++W IA+ GDL+ PC+ +++GF+ AFLFS+ET+TT
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 150 IGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVIS 209
IGYGFR +TE+CP +I ++VQ+I+G ++++FM+G + K+++PKKRA+TL+FS++AVIS
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 210 MRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLF 269
+RD KLCLM+RVG+LR SHIVEA +RA+LIK T+EGE++PL+Q D+NVG+D G DR+F
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 270 LVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLW 329
LVSP+II HEI++ SP + M + +L E+FE+VVILEGMVEAT MT QARSSY+ +E+LW
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
Query: 330 GHRFTPVLTLEKGFYEVDYNTFHDTYE-TNTPSCCAKELAEMKREGRLLQYLPSPPLLGG 388
GHRF PV+ EK Y+VDY+ FH TYE TP C A+EL E K + P PP
Sbjct: 315 GHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESK---ITVLPAPPPPPSAF 371
Query: 389 CAEAGLDAEAEQNEEDEPKGLGGSREARG 417
C E L +++ EE E + + A G
Sbjct: 372 CYENELALMSQEEEEMEEEAAAAAAVAAG 400
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 389 bits (1000), Expect = e-108
Identities = 191/389 (49%), Positives = 275/389 (70%), Gaps = 21/389 (5%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQ-ETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+K R R+++K+G+CNV+ N+ ++ RY++D+FTT VD +WR+ L++F+ + V+WLFFG
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 106 FIWWLIAYIRGDLD----------------HVGDQEWIPCVENLSGFVSAFLFSIETETT 149
++W IA+ GDL+ PC+ +++GF+ AFLFS+ET+TT
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 150 IGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVIS 209
IGYGFR +TE+CP +I ++VQ+I+G ++++FM+G + K+++PKKRA+TL+FS++AVIS
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 210 MRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLF 269
+RD KLCLM+RVG+LR SHIVEA +RA+LIK T+EGE++PL+Q D+NVG+D G DR+F
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 270 LVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLW 329
LVSP+II HEI++ SP + M + +L E+FE+VVILEGMVEAT MT QARSSY+ +E+LW
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
Query: 330 GHRFTPVLTLEKGFYEVDYNTFHDTYE-TNTPSCCAKELAEMKREGRLLQYLPSPPLLGG 388
GHRF PV+ EK Y+VDY+ FH TYE TP C A+EL E K + P PP
Sbjct: 315 GHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESK---ITVLPAPPPPPSAF 371
Query: 389 CAEAGLDAEAEQNEEDEPKGLGGSREARG 417
C E L +++ EE E + + A G
Sbjct: 372 CYENELALMSQEEEEMEEEAAAAAAVAAG 400
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 389 bits (999), Expect = e-108
Identities = 194/373 (52%), Positives = 271/373 (72%), Gaps = 11/373 (2%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
++ R R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 40 RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
I+W+IA GDL+ + PCV + GF++AFLFSIET+TTIGYG R +TE+CP +
Sbjct: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159
Query: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
+++ Q+I+G I+++FM+G + K+++PKKRA+TL+FS+NAV+++RD KLCLM+RVG+LR
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219
Query: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
SHIVEA +RA+LIK R T+EGE+IPL+Q DI+VGFD G DR+FLVSP+ I HEI++ SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
Query: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
+ +S+ L ++FE+VVILEGMVEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339
Query: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
+DY+ FH TYE +TP C AK+L E K LPS C E L A ++EED
Sbjct: 340 IDYSHFHKTYEVPSTPRCSAKDLVENK------FLLPSANSF--CYENEL-AFLSRDEED 390
Query: 405 EPKGLGGSREARG 417
E G R G
Sbjct: 391 EADGDQDGRSRDG 403
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 387 bits (995), Expect = e-108
Identities = 183/324 (56%), Positives = 253/324 (78%), Gaps = 4/324 (1%)
Query: 50 RQRYMEKSGKCNVHHGNVQET-YRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
R R+++K G CNV NV E RYL+D+FTT VD++WR+ L++F + + ++WLFFG ++
Sbjct: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
Query: 109 WLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILL 168
WLIA + GDLD +E CV ++ F +AFLFSIET+TTIGYGFR +T++CP + ++
Sbjct: 104 WLIALLHGDLD--ASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMV 161
Query: 169 LVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSH 228
+ Q+I+G I++AF++G + K+++PKKR ETL+FS+NAVI+MRD KLCLM+RVG+LR SH
Sbjct: 162 VFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSH 221
Query: 229 IVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWE 288
+VEA +RA+L+KSR T EGE+IPL+Q DINVGFD+G DR+FLVSP+ I HEI++ SP ++
Sbjct: 222 LVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYD 281
Query: 289 MSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDY 348
+S+ + +FE+VVILEGMVEAT MT Q RSSY+ E+LWGHR+ PVL EK +Y+VDY
Sbjct: 282 LSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDY 341
Query: 349 NTFHDTYET-NTPSCCAKELAEMK 371
+ FH TYE NTP C A++LAE K
Sbjct: 342 SRFHKTYEVPNTPLCSARDLAEKK 365
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 383 bits (983), Expect = e-106
Identities = 193/373 (51%), Positives = 268/373 (71%), Gaps = 11/373 (2%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
++ R R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 40 RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
I+W+IA GDL+ PCV + GF++AFLFSIET+TTIGYG R +TE+C +
Sbjct: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
Query: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
+++ Q+I+G I+++FM+G + K+++PKKRA TL+FS+NAV+++RD KLCLM+RVG+LR
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
Query: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
SHIVEA +RA+LIK R T+EGE+IPL+Q DI+VGFD G DR+FLVSP+ I HEI++ SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
Query: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
+ +S+ L ++FE+VVILEGMVEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339
Query: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
+DY+ FH TYE +TP C AK+L E K LPS C E L A ++EED
Sbjct: 340 IDYSHFHKTYEVPSTPRCSAKDLVENK------FLLPSANSF--CYENEL-AFLSRDEED 390
Query: 405 EPKGLGGSREARG 417
E G R G
Sbjct: 391 EADGDQDGRSRDG 403
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 371 bits (953), Expect = e-103
Identities = 185/375 (49%), Positives = 262/375 (69%), Gaps = 12/375 (3%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
++ R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 40 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
I+W+IA GDL+ + PCV + GF++AFLFSI+T+ TI YG R +TE+CP +
Sbjct: 100 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
+++ Q+I+G I+N+FM+G + K+ +PKKRA+TL+FS+NAV+++RD KLC M+RVG+LR
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
SHIVEA +RA+LIK R TKEGE+IPL+Q DI+VGFD G D FLVSP+ I HEI++ SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 279
Query: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
+ +S+ L ++FE+V+ILEG+VEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 280 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 338
Query: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
+DY FH TYE +TP C AK+L E K P C + L A ++EED
Sbjct: 339 IDYLHFHKTYEVPSTPRCSAKDLVENK--------FLLPRANSFCYKNEL-AFLSRDEED 389
Query: 405 EPKGLGGSREARGSV 419
E G R G +
Sbjct: 390 EADGDQDGRSREGLI 404
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 371 bits (953), Expect = e-103
Identities = 185/375 (49%), Positives = 262/375 (69%), Gaps = 12/375 (3%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
++ R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 142 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 201
Query: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
I+W+IA GDL+ + PCV + GF++AFLFSI+T+ TI YG R +TE+CP +
Sbjct: 202 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
Query: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
+++ Q+I+G I+N+FM+G + K+ +PKKRA+TL+FS+NAV+++RD KLC M+RVG+LR
Sbjct: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
Query: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
SHIVEA +RA+LIK R TKEGE+IPL+Q DI+VGFD G D FLVSP+ I HEI++ SP
Sbjct: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 381
Query: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
+ +S+ L ++FE+V+ILEG+VEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 382 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 440
Query: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
+DY FH TYE +TP C AK+L E K P C + L A ++EED
Sbjct: 441 IDYLHFHKTYEVPSTPRCSAKDLVENK--------FLLPRANSFCYKNEL-AFLSRDEED 491
Query: 405 EPKGLGGSREARGSV 419
E G R G +
Sbjct: 492 EADGDQDGRSREGLI 506
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 371 bits (953), Expect = e-103
Identities = 185/375 (49%), Positives = 262/375 (69%), Gaps = 12/375 (3%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
++ R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 40 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
I+W+IA GDL+ + PCV + GF++AFLFSI+T+ TI YG R +TE+CP +
Sbjct: 100 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
+++ Q+I+G I+N+FM+G + K+ +PKKRA+TL+FS+NAV+++RD KLC M+RVG+LR
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
SHIVEA +RA+LIK R TKEGE+IPL+Q DI+VGFD G D FLVSP+ I HEI++ SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 279
Query: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
+ +S+ L ++FE+V+ILEG+VEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 280 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 338
Query: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
+DY FH TYE +TP C AK+L E K P C + L A ++EED
Sbjct: 339 IDYLHFHKTYEVPSTPRCSAKDLVENK--------FLLPRANSFCYKNEL-AFLSRDEED 389
Query: 405 EPKGLGGSREARGSV 419
E G R G +
Sbjct: 390 EADGDQDGRSREGLI 404
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 351 bits (900), Expect = 8e-97
Identities = 182/375 (48%), Positives = 253/375 (67%), Gaps = 9/375 (2%)
Query: 50 RQRYMEKSGKCNVHHGNVQ-ETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
R R+++K G CNV N+ + RYLSDLFTT VD++WR+ L+F+ + +WL FG +
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 109 WLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILL 168
WLIA + GDL PC +++ F++AFLF++ET+T+IGYG R +TE+CP + +
Sbjct: 109 WLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAV 166
Query: 169 LVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSH 228
++Q I G +++AF+VG + K+++PKKR ETL+FS NAV+++RD +LCLM+RVG+LR SH
Sbjct: 167 VLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSH 226
Query: 229 IVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWE 288
+VEA +RA+L++ R T EGE+IPL+ D++VGFD G DR+FLVSP+ I HEI+ SP +E
Sbjct: 227 LVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYE 286
Query: 289 MSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDY 348
+ +A+L + +FE+VVILEGMVEAT MT Q RSSY+ E+LWGHRF PVL YEVDY
Sbjct: 287 LGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDY 346
Query: 349 NTFHDTYET-NTPSCCAKELAEMKREG--RLLQYLPSPPLLGGC--AEAGLDAEAEQNEE 403
FH TYE TP C AKEL E + L P L C E L E++E+
Sbjct: 347 RHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPG-SLTAFCYENELALSCCQEEDED 405
Query: 404 DEPKGLGGSREARGS 418
DE + G G+
Sbjct: 406 DETEEGNGVETEDGA 420
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 351 bits (900), Expect = 8e-97
Identities = 182/375 (48%), Positives = 253/375 (67%), Gaps = 9/375 (2%)
Query: 50 RQRYMEKSGKCNVHHGNVQ-ETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
R R+++K G CNV N+ + RYLSDLFTT VD++WR+ L+F+ + +WL FG +
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 109 WLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILL 168
WLIA + GDL PC +++ F++AFLF++ET+T+IGYG R +TE+CP + +
Sbjct: 109 WLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAV 166
Query: 169 LVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSH 228
++Q I G +++AF+VG + K+++PKKR ETL+FS NAV+++RD +LCLM+RVG+LR SH
Sbjct: 167 VLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSH 226
Query: 229 IVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWE 288
+VEA +RA+L++ R T EGE+IPL+ D++VGFD G DR+FLVSP+ I HEI+ SP +E
Sbjct: 227 LVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYE 286
Query: 289 MSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDY 348
+ +A+L + +FE+VVILEGMVEAT MT Q RSSY+ E+LWGHRF PVL YEVDY
Sbjct: 287 LGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDY 346
Query: 349 NTFHDTYET-NTPSCCAKELAEMKREG--RLLQYLPSPPLLGGC--AEAGLDAEAEQNEE 403
FH TYE TP C AKEL E + L P L C E L E++E+
Sbjct: 347 RHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPG-SLTAFCYENELALSCCQEEDED 405
Query: 404 DEPKGLGGSREARGS 418
DE + G G+
Sbjct: 406 DETEEGNGVETEDGA 420
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 337 bits (863), Expect = 2e-92
Identities = 160/329 (48%), Positives = 231/329 (70%), Gaps = 8/329 (2%)
Query: 49 PRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
P+ R++ KSG CN+ H N++E R+L D+FTTLVDLKWR L++FTM + +WL F +W
Sbjct: 32 PKARFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
Query: 109 WLIAYIRGDLDHVGDQ--------EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160
WL+A+ GD+ ++ E CV N+ F SAFLFSIE + TIG+G R++TE+
Sbjct: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
Query: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220
CP I +L++Q I+G I+NA M+GC+F+K +Q +RAETL+FS +AVI++R+ KLC MFR
Sbjct: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
Query: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280
VGDLR S I+ AS+R +++K T EGE +P++Q DI V + +FLV+PLII H I
Sbjct: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
Query: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340
+++SP +++S L ++ EV+VILEG+VE TG+T QAR+SY+ E+ WGHRF ++T E
Sbjct: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
Query: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAE 369
+G Y VDY+ F +T + P C A+EL E
Sbjct: 332 EGVYSVDYSKFGNTVKVAAPRCSARELDE 360
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 330 bits (847), Expect = 1e-90
Identities = 163/339 (48%), Positives = 232/339 (68%), Gaps = 11/339 (3%)
Query: 40 TRLLAEGKKPRQR-------YMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLV 92
TRL + KPR R ++ K G CNV H N++E R+L D+FTTLVDLKW LL+
Sbjct: 15 TRLAEDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLI 74
Query: 93 FTMVYTVTWLFFGFIWWLIAYIRGDL-DHVGDQEWIPCVENLSGFVSAFLFSIETETTIG 151
FTM + +WL F WWLIA+ GDL G E PCV ++ F SAFLFSIE + TIG
Sbjct: 75 FTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIG 132
Query: 152 YGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMR 211
+G R++TE+CP I++L+VQ I+G ++NA M+GC+F+K +Q +RAETL+FS +AVI++R
Sbjct: 133 FGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALR 192
Query: 212 DEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLV 271
+LC M RVGDLR S I+ A+I ++++ + EGE +PL+Q DI + G + +FLV
Sbjct: 193 HGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLV 252
Query: 272 SPLIISHEINQKSPFWEMSQAQL-HQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWG 330
+PLII H I+ SP ++++ + L H ++ E++VILEG+VE TG+T QAR+SY+ E+LWG
Sbjct: 253 APLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWG 312
Query: 331 HRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAE 369
RF P++ E G Y VDY+ F +T + TP C A++L E
Sbjct: 313 QRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDE 351
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 162/364 (44%), Positives = 229/364 (62%), Gaps = 14/364 (3%)
Query: 48 KPRQRYMEKSGKCNVHHGNVQETYRYLS--DLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+ R R + K G+CN+ GNV+ R++ D++TT++DLKWR+ + +F + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 FIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEG 164
+W+ +AYI DL PCVEN++G SAFLFS+ET+ TIGYGFR +TE+C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 165 IILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDL 224
I LL+ Q+ILG I+N+FM G + KIS+PKKRA+T+ FS NAVIS R KLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 225 RNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKS 284
R S ++ + I KL+K+ T EGE I L+Q +IN D G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 285 PFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-GF 343
PF+ M+ L Q++FE+VV L+G VE+T TCQ R+SY+ EVLWG+RF P+++ K G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 344 YEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEE 403
Y VD++ F T E TP C E R+ + +P + +E NE
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKRGYDNPNFI----------LSEVNET 367
Query: 404 DEPK 407
D+ K
Sbjct: 368 DDTK 371
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 162/364 (44%), Positives = 229/364 (62%), Gaps = 14/364 (3%)
Query: 48 KPRQRYMEKSGKCNVHHGNVQETYRYLS--DLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+ R R + K G+CN+ GNV+ R++ D++TT++DLKWR+ + +F + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 FIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEG 164
+W+ +AYI DL PCVEN++G SAFLFS+ET+ TIGYGFR +TE+C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 165 IILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDL 224
I LL+ Q+ILG I+N+FM G + KIS+PKKRA+T+ FS NAVIS R KLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 225 RNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKS 284
R S ++ + I KL+K+ T EGE I L+Q +IN D G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 285 PFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-GF 343
PF+ M+ L Q++FE+VV L+G VE+T TCQ R+SY+ EVLWG+RF P+++ K G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 344 YEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEE 403
Y VD++ F T E TP C E R+ + +P + +E NE
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKRGYDNPNFI----------LSEVNET 367
Query: 404 DEPK 407
D+ K
Sbjct: 368 DDTK 371
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 316 bits (810), Expect = 2e-86
Identities = 162/364 (44%), Positives = 229/364 (62%), Gaps = 14/364 (3%)
Query: 48 KPRQRYMEKSGKCNVHHGNVQETYRYLS--DLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+ R R + K G+CN+ GNV+ R++ D++TT++DLKWR+ + +F + +W FFG
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 106 FIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEG 164
+W+ +AYI DL PCVEN++G SAFLFS+ET+ TIGYGFR +TE+C
Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156
Query: 165 IILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDL 224
I LL+ Q+ILG I+N+FM G + KIS+PKKRA+T+ FS NAVIS R KLCL+ RV +L
Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216
Query: 225 RNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKS 284
R S ++ + I KL+K+ T EGE I L+Q +IN D G++ LF +SPL I H I+ S
Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 276
Query: 285 PFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-GF 343
PF+ M+ L Q++FE+VV L+G VE+T TCQ R+SY+ EVLWG+RF P+++ K G
Sbjct: 277 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 336
Query: 344 YEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEE 403
Y VD++ F T E TP C E R+ + +P + +E NE
Sbjct: 337 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKRGYDNPNFI----------LSEVNET 386
Query: 404 DEPK 407
D+ K
Sbjct: 387 DDTK 390
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 162/364 (44%), Positives = 229/364 (62%), Gaps = 14/364 (3%)
Query: 48 KPRQRYMEKSGKCNVHHGNVQETYRYLS--DLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+ R R + K G+CN+ GNV+ R++ D++TT++DLKWR+ + +F + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 FIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEG 164
+W+ +AYI DL PCVEN++G SAFLFS+ET+ TIGYGFR +TE+C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 165 IILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDL 224
I LL+ Q+ILG I+N+FM G + KIS+PKKRA+T+ FS NAVIS R KLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 225 RNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKS 284
R S ++ + I KL+K+ T EGE I L+Q +IN D G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 285 PFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-GF 343
PF+ M+ L Q++FE+VV L+G VE+T TCQ R+SY+ EVLWG+RF P+++ K G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 344 YEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEE 403
Y VD++ F T E TP C E R+ + +P + +E NE
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKRGYDNPNFI----------LSEVNET 367
Query: 404 DEPK 407
D+ K
Sbjct: 368 DDTK 371
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 162/364 (44%), Positives = 229/364 (62%), Gaps = 14/364 (3%)
Query: 48 KPRQRYMEKSGKCNVHHGNVQETYRYLS--DLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
+ R R + K G+CN+ GNV+ R++ D++TT++DLKWR+ + +F + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 FIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEG 164
+W+ +AYI DL PCVEN++G SAFLFS+ET+ TIGYGFR +TE+C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 165 IILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDL 224
I LL+ Q+ILG I+N+FM G + KIS+PKKRA+T+ FS NAVIS R KLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 225 RNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKS 284
R S ++ + I KL+K+ T EGE I L+Q +IN D G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 285 PFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-GF 343
PF+ M+ L Q++FE+VV L+G VE+T TCQ R+SY+ EVLWG+RF P+++ K G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 344 YEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEE 403
Y VD++ F T E TP C E R+ + +P + +E NE
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKRGYDNPNFI----------LSEVNET 367
Query: 404 DEPK 407
D+ K
Sbjct: 368 DDTK 371
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 278 bits (712), Expect = 5e-75
Identities = 136/349 (38%), Positives = 228/349 (65%), Gaps = 11/349 (3%)
Query: 42 LLAEGKKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT 100
++AE ++ R+R + K G CNV+ ++ E Y+ D+FTTLVD KWR ++F++ Y ++
Sbjct: 25 IIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILS 84
Query: 101 WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160
WL FG ++WLIA+ GDL + D + PCV+N+ F AFLFS+ET+TTIGYG+R +TE+
Sbjct: 85 WLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEE 142
Query: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220
C ++++++Q+IL I+N F++G K++ +KRA+T+ FS A+I MRD KLCLM+R
Sbjct: 143 CSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWR 202
Query: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280
+GD R +H+VE ++RA+L++ + EG + + D+ + +D++ LV+P+ I HEI
Sbjct: 203 IGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEI 257
Query: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340
+ +SP + + + + ++ FE++V ++TG + Q+RSSY+ E+LWGHRF VL ++
Sbjct: 258 DHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVK 317
Query: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGC 389
+ +Y+V+ F + E P C AK+L ++ L +PP+ C
Sbjct: 318 RKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQ---LHIEKAPPVRESC 363
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 278 bits (712), Expect = 5e-75
Identities = 136/349 (38%), Positives = 228/349 (65%), Gaps = 11/349 (3%)
Query: 42 LLAEGKKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT 100
++AE ++ R+R + K G CNV+ ++ E Y+ D+FTTLVD KWR ++F++ Y ++
Sbjct: 25 IIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILS 84
Query: 101 WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160
WL FG ++WLIA+ GDL + D + PCV+N+ F AFLFS+ET+TTIGYG+R +TE+
Sbjct: 85 WLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEE 142
Query: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220
C ++++++Q+IL I+N F++G K++ +KRA+T+ FS A+I MRD KLCLM+R
Sbjct: 143 CSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWR 202
Query: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280
+GD R +H+VE ++RA+L++ + EG + + D+ + +D++ LV+P+ I HEI
Sbjct: 203 IGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEI 257
Query: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340
+ +SP + + + + ++ FE++V ++TG + Q+RSSY+ E+LWGHRF VL ++
Sbjct: 258 DHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVK 317
Query: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGC 389
+ +Y+V+ F + E P C AK+L ++ L +PP+ C
Sbjct: 318 RKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQ---LHIEKAPPVRESC 363
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 278 bits (712), Expect = 5e-75
Identities = 136/349 (38%), Positives = 228/349 (65%), Gaps = 11/349 (3%)
Query: 42 LLAEGKKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT 100
++AE ++ R+R + K G CNV+ ++ E Y+ D+FTTLVD KWR ++F++ Y ++
Sbjct: 25 IIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILS 84
Query: 101 WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160
WL FG ++WLIA+ GDL + D + PCV+N+ F AFLFS+ET+TTIGYG+R +TE+
Sbjct: 85 WLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEE 142
Query: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220
C ++++++Q+IL I+N F++G K++ +KRA+T+ FS A+I MRD KLCLM+R
Sbjct: 143 CSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWR 202
Query: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280
+GD R +H+VE ++RA+L++ + EG + + D+ + +D++ LV+P+ I HEI
Sbjct: 203 IGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEI 257
Query: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340
+ +SP + + + + ++ FE++V ++TG + Q+RSSY+ E+LWGHRF VL ++
Sbjct: 258 DHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVK 317
Query: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGC 389
+ +Y+V+ F + E P C AK+L ++ L +PP+ C
Sbjct: 318 RKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQ---LHIEKAPPVRESC 363
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 263 bits (673), Expect = 2e-70
Identities = 132/328 (40%), Positives = 205/328 (62%), Gaps = 5/328 (1%)
Query: 37 TDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQET-YRYLSDLFTTLVDLKWRFNLLVFTM 95
T+ L+ G + R+R + K G+ NV ++ + + YL DL+TT +D++WR+ LL+F+
Sbjct: 15 TESRPLMGPGIR-RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSA 73
Query: 96 VYTVTWLFFGFIWWLIAYIRGDLDHVGDQ-EWIPCVENLSGFVSAFLFSIETETTIGYGF 154
+ TW FG +W+L+A GDL + PCV + AFLFS+E++TTIGYGF
Sbjct: 74 TFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGF 133
Query: 155 RVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEK 214
R I+E+CP I+LL+ Q +L +I+ F+ G KI++PKKRAET+ FS +AV++ + K
Sbjct: 134 RYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGK 193
Query: 215 LCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPL 274
CLM RV ++R S ++ + KL+++ QTKEGE I LNQ ++ DT D FL+ PL
Sbjct: 194 PCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPL 253
Query: 275 IISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFT 334
H +++ SP ++ + + +FE+V+IL G VE+T TCQ R+SY+ E+LWG+ FT
Sbjct: 254 TFYHVVDETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFT 312
Query: 335 PVLTLE-KGFYEVDYNTFHDTYETNTPS 361
P ++L G Y D++ F + +PS
Sbjct: 313 PAISLSASGKYIADFSLFDQVVKVASPS 340
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 258 bits (658), Expect = 9e-69
Identities = 129/320 (40%), Positives = 198/320 (61%), Gaps = 7/320 (2%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQETYR-YLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
K R R M KSG NV V Y YL DL+TT++D+KWR+ L +F + +TW FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 106 FIWWLIAYIRGDLDHVGD--QEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163
I++ IA+I GDL+ G+ PC+ + AFLFS+E++TTIGYG R ITE+CP
Sbjct: 83 VIYYAIAFIHGDLEP-GEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPH 141
Query: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223
I LL+ Q ++ +++ F+ G KI++PKKRAET+ FS+ AVI+ ++ KLCL+ +V +
Sbjct: 142 AIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVAN 201
Query: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283
+R S +++ + KL+++ TKEGE I LNQ + D+ + FL+ P+ H +++
Sbjct: 202 MRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDET 261
Query: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-G 342
SP +++ L ++EFE+VV+L VE+T CQ+R+SY+ E+ WG F PV++L K G
Sbjct: 262 SPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
Query: 343 FYEVDYNTFHDTYETNTPSC 362
Y D++ F +P C
Sbjct: 322 KYVADFSQFEQI--RKSPDC 339
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 258 bits (658), Expect = 9e-69
Identities = 129/320 (40%), Positives = 198/320 (61%), Gaps = 7/320 (2%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQETYR-YLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
K R R M KSG NV V Y YL DL+TT++D+KWR+ L +F + +TW FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 106 FIWWLIAYIRGDLDHVGD--QEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163
I++ IA+I GDL+ G+ PC+ + AFLFS+E++TTIGYG R ITE+CP
Sbjct: 83 VIYYAIAFIHGDLEP-GEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPH 141
Query: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223
I LL+ Q ++ +++ F+ G KI++PKKRAET+ FS+ AVI+ ++ KLCL+ +V +
Sbjct: 142 AIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVAN 201
Query: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283
+R S +++ + KL+++ TKEGE I LNQ + D+ + FL+ P+ H +++
Sbjct: 202 MRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDET 261
Query: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-G 342
SP +++ L ++EFE+VV+L VE+T CQ+R+SY+ E+ WG F PV++L K G
Sbjct: 262 SPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
Query: 343 FYEVDYNTFHDTYETNTPSC 362
Y D++ F +P C
Sbjct: 322 KYVADFSQFEQI--RKSPDC 339
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 258 bits (658), Expect = 9e-69
Identities = 129/320 (40%), Positives = 198/320 (61%), Gaps = 7/320 (2%)
Query: 47 KKPRQRYMEKSGKCNVHHGNVQETYR-YLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
K R R M KSG NV V Y YL DL+TT++D+KWR+ L +F + +TW FG
Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
Query: 106 FIWWLIAYIRGDLDHVGD--QEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163
I++ IA+I GDL+ G+ PC+ + AFLFS+E++TTIGYG R ITE+CP
Sbjct: 83 VIYYAIAFIHGDLEP-GEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPH 141
Query: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223
I LL+ Q ++ +++ F+ G KI++PKKRAET+ FS+ AVI+ ++ KLCL+ +V +
Sbjct: 142 AIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVAN 201
Query: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283
+R S +++ + KL+++ TKEGE I LNQ + D+ + FL+ P+ H +++
Sbjct: 202 MRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDET 261
Query: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-G 342
SP +++ L ++EFE+VV+L VE+T CQ+R+SY+ E+ WG F PV++L K G
Sbjct: 262 SPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
Query: 343 FYEVDYNTFHDTYETNTPSC 362
Y D++ F +P C
Sbjct: 322 KYVADFSQFEQI--RKSPDC 339
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 182 bits (463), Expect = 4e-46
Identities = 107/310 (34%), Positives = 168/310 (54%), Gaps = 12/310 (3%)
Query: 51 QRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWL 110
+R + K G + Q YL D + L+D++WR+ +LVF+ + V WL F +W++
Sbjct: 18 RRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
Query: 111 IAYIRGDL--DHVGDQE-WIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIIL 167
+A + GDL DH E CV+ ++ F +AF FS+ET+ TIGYG + CP I L
Sbjct: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
Query: 168 LLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNS 227
L +Q +LG ++ AF+ G KI++PK RA ++ F++ AV++ D K L+F+V + R S
Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
Query: 228 HIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFD--TGDDRLFLVSPLIISHEINQKSP 285
+ + A L + R+ + L QT ++ D + D+ F + PL H I SP
Sbjct: 198 PLTSVRVSAVLYQERENGK-----LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
Query: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTL-EKGFY 344
+ Q + + FE+VV L M E TG CQ R+SY+ +E++ H F +LT KG Y
Sbjct: 253 LATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
Query: 345 EVDYNTFHDT 354
++ F T
Sbjct: 312 QIKMENFDKT 321
>gi|31377765 transmembrane protein 87A isoform 1 [Homo sapiens]
Length = 555
Score = 32.3 bits (72), Expect = 0.82
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 13/67 (19%)
Query: 74 LSDLFTTLVDLKWRFN--------LLVFTMVYTVTWLFFGFIW--WLIAYIRGDLDHVGD 123
LS+LFT V++K + L++F MV + ++ FG +W W Y R D +
Sbjct: 202 LSNLFTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWR---DLLRI 258
Query: 124 QEWIPCV 130
Q WI V
Sbjct: 259 QFWIGAV 265
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,061,051
Number of Sequences: 37866
Number of extensions: 635314
Number of successful extensions: 1672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1575
Number of HSP's gapped (non-prelim): 45
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.