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Search of human proteins with 24430144
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens] 438 e-123
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens] 395 e-110
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] 386 e-108
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens] 374 e-104
gi|169169045 PREDICTED: similar to glutathione S-transferase alp... 263 7e-71
gi|113417526 PREDICTED: similar to glutathione S-transferase alp... 263 7e-71
gi|113418092 PREDICTED: similar to glutathione S-transferase alp... 262 2e-70
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens] 253 1e-67
gi|4504183 glutathione transferase [Homo sapiens] 86 3e-17
gi|7657457 prostaglandin-D synthase [Homo sapiens] 68 7e-12
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens] 61 9e-10
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens] 60 1e-09
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi... 57 1e-08
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens] 56 3e-08
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens] 54 8e-08
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens] 54 1e-07
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens] 50 2e-06
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens] 48 8e-06
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens] 46 3e-05
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens] 44 1e-04
gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo sapi... 32 0.56
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 31 0.96
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept... 29 2.8
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso... 29 2.8
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof... 29 2.8
gi|19913398 smoothelin isoform a [Homo sapiens] 29 3.7
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens] 28 4.8
gi|44955921 ELK3 protein [Homo sapiens] 28 4.8
gi|33620755 YEATS domain containing 2 [Homo sapiens] 28 4.8
gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2 [... 28 8.2
>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
Length = 222
Score = 438 bits (1127), Expect = e-123
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
Length = 222
Score = 395 bits (1015), Expect = e-110
Identities = 201/222 (90%), Positives = 208/222 (93%)
Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
MA KPKLHYFN RGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI
Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMY EG+ADL EMILLLP+C PEEKDAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
+ALIKEK K+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL
Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
Length = 222
Score = 386 bits (992), Expect = e-108
Identities = 197/222 (88%), Positives = 208/222 (93%)
Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
MA KPKLHY N RGRME IRWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI
Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMY EG+ADL EMILLLP +PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
+ALI+EKTK+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL
Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
Length = 222
Score = 374 bits (959), Expect = e-104
Identities = 190/222 (85%), Positives = 202/222 (90%)
Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
MA KPKLHY N RG ME IRWLLAAAGVE EEKF+ SAEDL KLRNDGSL+FQQVPMVEI
Sbjct: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMYTEG+ DL EMILLL +C+PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
AL+KEK K+RYFPAFEKVL+SH QDYLVGNKLS ADI LVEL YYVEELDSSLIS+FPL
Sbjct: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGS RKPP D K+LEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 227
Score = 263 bits (673), Expect = 7e-71
Identities = 148/221 (66%), Positives = 165/221 (74%), Gaps = 16/221 (7%)
Query: 17 EPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIA 76
+P L+ + E E KF+ SA+DL KLRND S MFQQVPMVEIDGMKLVQTRAILNYI
Sbjct: 6 KPFSLTLSQSYEESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIV 65
Query: 77 SKYNLYGKDIKERA---------LIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEK 127
SKYNL GKDIKERA +DMY EG A L+E +L L PEEKDAK+ALIKE
Sbjct: 66 SKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEG 125
Query: 128 TKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK----- 182
T S YFP FE VL+SH QDYL+GNKLS+ADI LV+LLY+VEE DSSLISNFP+LK
Sbjct: 126 TTSHYFPVFETVLKSHEQDYLIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCA 185
Query: 183 --ALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221
ALK RIS LPTVKKFLQPGS RK P DAK L+EA KIF+
Sbjct: 186 LRALKIRISKLPTVKKFLQPGSLRKLPIDAKGLQEATKIFK 226
>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 263 bits (673), Expect = 7e-71
Identities = 147/210 (70%), Positives = 161/210 (76%), Gaps = 16/210 (7%)
Query: 28 VEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIK 87
VE E KF+ SA+DL KLRND S MFQQVPMVEIDGMKLVQTRAILNYIASKYNL GKDIK
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIK 65
Query: 88 ERA---------LIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEK 138
ERA +DMY EG A L+E +L L PEEKDAK+ALIKE T S YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK-------ALKTRISNL 191
VL+SH QDY +GNKLS+ADI LV+LLY+VEE DSSLISNFP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSPRKPPADAKALEEARKIFR 221
PTVKKFLQPGS RK P DAK L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 262 bits (669), Expect = 2e-70
Identities = 146/210 (69%), Positives = 160/210 (76%), Gaps = 16/210 (7%)
Query: 28 VEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIK 87
VE E KF+ SA+DL KLRND S MFQQVPMVEIDGMKLVQTRAILNYI SKYNL GKDIK
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIK 65
Query: 88 ERA---------LIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEK 138
ERA +DMY EG A L+E +L L PEEKDAK+ALIKE T S YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK-------ALKTRISNL 191
VL+SH QDY +GNKLS+ADI LV+LLY+VEE DSSLISNFP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSPRKPPADAKALEEARKIFR 221
PTVKKFLQPGS RK P DAK L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
Length = 222
Score = 253 bits (645), Expect = 1e-67
Identities = 118/221 (53%), Positives = 167/221 (75%)
Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
MA +PKLHY NGRGRME +RW+LAAAGVEF+E+F+ + E L KL++ L+FQQVPMVEI
Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG DL E++++ P +P+++ +
Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
+ + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S FP
Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221
L+ ++SN+PT+K+FL+PGS +KPP D + IFR
Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
>gi|4504183 glutathione transferase [Homo sapiens]
Length = 210
Score = 85.9 bits (211), Expect = 3e-17
Identities = 62/193 (32%), Positives = 100/193 (51%), Gaps = 9/193 (4%)
Query: 9 YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQT 68
YF RGR +R LLA G ++E+ + + E + S ++ Q+P + + L Q+
Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66
Query: 69 RAILNYIASKYNLYGKDIKERALIDMYTEGMADLN-EMILLLPLCRPEEKDAKIALIKEK 127
IL ++ LYGKD +E AL+DM +G+ DL + I L+ KD + + +
Sbjct: 67 NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126
Query: 128 TKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALK 185
K FE +L + G+ ++VG+++S AD +L++LL E L + FPLL A
Sbjct: 127 LK-----PFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181
Query: 186 TRISNLPTVKKFL 198
R+S P +K FL
Sbjct: 182 GRLSARPKLKAFL 194
>gi|7657457 prostaglandin-D synthase [Homo sapiens]
Length = 199
Score = 67.8 bits (164), Expect = 7e-12
Identities = 54/200 (27%), Positives = 104/200 (52%), Gaps = 18/200 (9%)
Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65
KL YFN RGR E IR++ A +++E+ I A D ++++ +L F ++P++E+DG+ L
Sbjct: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDGLTL 61
Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIK 125
Q+ AI Y+ +L G E+ +D + L++ + P +++D K +
Sbjct: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD---TLDDFMSCFPWAE-KKQDVKEQMFN 117
Query: 126 EKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRAD----ISLVELLYYVEELDSSLISNFP 179
E + P + L ++ G+++L+GN ++ AD I LL + + L+ N P
Sbjct: 118 E-LLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPD----LLDNHP 172
Query: 180 LLKALKTRISNLPTVKKFLQ 199
L L+ ++ +P V +++
Sbjct: 173 RLVTLRKKVQAIPAVANWIK 192
>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
Length = 225
Score = 60.8 bits (146), Expect = 9e-10
Identities = 58/224 (25%), Positives = 89/224 (39%), Gaps = 22/224 (9%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGK-----LRNDGSLMFQQVPMVE 59
L Y++ RG IR LL +EEK G A D + ++ L F +P +
Sbjct: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119
K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D L+ LC +
Sbjct: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ--LIRLCYSSD--- 123
Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174
EK K +Y L+ + G KL+ D ++L D
Sbjct: 124 -----HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178
Query: 175 ISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218
+ FP LKA R L + +LQ K P + K + K
Sbjct: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222
>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
Length = 218
Score = 60.5 bits (145), Expect = 1e-09
Identities = 59/206 (28%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y+N RG IR LL +EEK +G A D + + N+ L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L LC +
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD--SRMQLAKLCYDPD-- 119
Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHG-----QDYLVGNKLSRADISLVELLYYVEELDSS 173
EK K Y A ++L+ + Q + +G+K++ D ++L + + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173
Query: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199
+ FP LK +R L + +++
Sbjct: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199
>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
sapiens]
Length = 191
Score = 57.0 bits (136), Expect = 1e-08
Identities = 58/197 (29%), Positives = 90/197 (45%), Gaps = 24/197 (12%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y+N RG IR LL +EEK +G A D + + N+ L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L LC +
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD--SRMQLAKLCYDPD-- 119
Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHG-----QDYLVGNKLSRADISLVELLYYVEELDSS 173
EK K Y A ++L+ + Q + +G+K++ D ++L + + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173
Query: 174 LISNFPLLKALKTRISN 190
+ FP LK +R +
Sbjct: 174 CLDAFPNLKDFISRFEH 190
>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
Length = 218
Score = 55.8 bits (133), Expect = 3e-08
Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y++ RG IR LL +EEK +G A D + + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D N M L + PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174
EK K +Y + L+ + + + GNK++ D + ++L +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
Query: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199
+ FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
Length = 216
Score = 54.3 bits (129), Expect = 8e-08
Identities = 49/193 (25%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGK-LRNDGSLM--FQQVPMV 58
AGKP L+ + +R LA G+++E I +D G+ D + +QVP +
Sbjct: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTL 62
Query: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115
+IDG+ + Q+ AI+ Y+ L +D K+RA + M ++ +A + + L + +
Sbjct: 63 KIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQV 122
Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175
++ ++ + F A E++LQS Y VG++++ AD+ LV + E L
Sbjct: 123 GEEMQLTWAQNAITCG-FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL- 180
Query: 176 SNFPLLKALKTRI 188
+ +P + ++ R+
Sbjct: 181 TPYPTISSINKRL 193
>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
Length = 218
Score = 53.9 bits (128), Expect = 1e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 22/205 (10%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y++ RG IR LL +EEK +G A D + + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D++ L +C +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD--- 119
Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174
EK K Y ++Q Q + VG+K++ D ++L + +
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174
Query: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199
+ FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
Length = 195
Score = 50.1 bits (118), Expect = 2e-06
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 22/193 (11%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y++ RG IR LL +EEK +G A D + + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D++ L +C +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD--- 119
Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174
EK K Y ++Q Q + VG+K++ D ++L + +
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174
Query: 175 ISNFPLLKALKTR 187
+ FP LK +R
Sbjct: 175 LDAFPNLKDFISR 187
>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
Length = 218
Score = 47.8 bits (112), Expect = 8e-06
Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 22/205 (10%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y++ RG IR LL + EK +G A D + + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ + D N M L+ P+
Sbjct: 65 DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174
EK K +Y + L+ + + + G+K++ D ++L +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
Query: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199
+ F LK +R L + +++
Sbjct: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
Length = 161
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/139 (25%), Positives = 72/139 (51%), Gaps = 5/139 (3%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLL 109
+QVP ++IDG+ + Q+ AI+ Y+ L +D K+RA + M ++ +A + + L
Sbjct: 2 KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 61
Query: 110 PLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEE 169
+ + ++ ++ + F A E++LQS Y VG++++ AD+ LV + E
Sbjct: 62 SVLKQVGEEMQLTWAQNAITCG-FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 120
Query: 170 LDSSLISNFPLLKALKTRI 188
L + +P + ++ R+
Sbjct: 121 FKVDL-TPYPTISSINKRL 138
>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
Length = 181
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/127 (31%), Positives = 61/127 (48%), Gaps = 8/127 (6%)
Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59
L Y++ RG IR LL +EEK +G A D + + N+ L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D N M L + PE +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPEFEKL 123
Query: 120 KIALIKE 126
K ++E
Sbjct: 124 KPKYLEE 130
>gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
sapiens]
Length = 174
Score = 31.6 bits (70), Expect = 0.56
Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 44/190 (23%)
Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGK-LRNDGSLM--FQQVPMV 58
AGKP L+ + +R LA G+++E I +D G+ D + +QVP +
Sbjct: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTL 62
Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118
+IDG+ + Q+ S G++++ + T G
Sbjct: 63 KIDGITIHQSNL------SVLKQVGEEMQLTWAQNAITCG-------------------- 96
Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178
F A E++LQS Y VG++++ AD+ LV + E L + +
Sbjct: 97 --------------FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPY 141
Query: 179 PLLKALKTRI 188
P + ++ R+
Sbjct: 142 PTISSINKRL 151
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 30.8 bits (68), Expect = 0.96
Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 17 EPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF-------QQVPMVEIDGMKLVQTR 69
+PIR L+A A E E+ E+ + + SL + + + KL Q
Sbjct: 298 KPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNA 357
Query: 70 AILNYIASKYN-------LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122
IL ++ K L K + E+ D + + D+NE I L E + A
Sbjct: 358 CILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTA 417
Query: 123 LIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLS 154
+IKE + + P E + + Q+ + N +S
Sbjct: 418 VIKENEREKR-PKLENLPDTEDQETVDINSVS 448
>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
[Homo sapiens]
Length = 1068
Score = 29.3 bits (64), Expect = 2.8
Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 145 QDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKAL 184
+ YL +KLS+ I LV++L Y + LD+ L+ F L KAL
Sbjct: 620 EKYLTDDKLSQYLIQLVQVLKYEQYLDNLLV-RFLLKKAL 658
>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
isoform 1 [Homo sapiens]
Length = 435
Score = 29.3 bits (64), Expect = 2.8
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 31/158 (19%)
Query: 81 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL 140
+Y D+K + LI G D++E+ +P+ +E++ ++ I R+ +
Sbjct: 6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRF------MW 59
Query: 141 QSHGQDYLVGNKLSRADISLV-ELLY--------YVEEL-DSSLISNFPLLKALKTRISN 190
H YLV A +SLV LY Y +EL + S+ NF ++ L + +
Sbjct: 60 IKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMD 119
Query: 191 L----PTVKKFLQ-----------PGSPRKPPADAKAL 213
T K LQ G+PR P A+
Sbjct: 120 FGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAV 157
>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
2 [Homo sapiens]
Length = 423
Score = 29.3 bits (64), Expect = 2.8
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 31/158 (19%)
Query: 81 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL 140
+Y D+K + LI G D++E+ +P+ +E++ ++ I R+ +
Sbjct: 6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRF------MW 59
Query: 141 QSHGQDYLVGNKLSRADISLV-ELLY--------YVEEL-DSSLISNFPLLKALKTRISN 190
H YLV A +SLV LY Y +EL + S+ NF ++ L + +
Sbjct: 60 IKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMD 119
Query: 191 L----PTVKKFLQ-----------PGSPRKPPADAKAL 213
T K LQ G+PR P A+
Sbjct: 120 FGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAV 157
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 28.9 bits (63), Expect = 3.7
Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 39 EDLGKLRN-DGSLMFQQVPMVEIDGMKLV----QTRAILNYIASKYN 80
ED+ +LR D ++ VP+VE+D M ++ + + Y+ S YN
Sbjct: 880 EDMVRLREPDWKMLVDCVPLVEVDDMMIMGKKPDPKCVFTYVQSLYN 926
>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
Length = 240
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDIKERALIDMY 95
++VP ++ L ++ AIL Y+ KY + Y +D++ RA +D Y
Sbjct: 52 KKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEY 98
>gi|44955921 ELK3 protein [Homo sapiens]
Length = 407
Score = 28.5 bits (62), Expect = 4.8
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
Query: 168 EELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
E + S L S+F + + N P K ++ +PP D+ +EE R + RF
Sbjct: 136 EYIHSGLYSSFTI-----NSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRF 185
>gi|33620755 YEATS domain containing 2 [Homo sapiens]
Length = 1422
Score = 28.5 bits (62), Expect = 4.8
Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 19/118 (16%)
Query: 114 PEEKDAKIALIKEKTK----SRYFPAFEKVLQSHGQDYLVGNKLSRADIS-----LVELL 164
P+ +D +AL ++ K S A +K+ + + + K +I L+E
Sbjct: 13 PDYEDVSVALPNKRHKAIENSARDAAVQKIETIIKEQFALEMKNKEHEIEVIDQRLIEAR 72
Query: 165 YYVEELDSSLISNF----PLLKALK------TRISNLPTVKKFLQPGSPRKPPADAKA 212
+++L + +++N+ LLK + T + N P +KKFL+ S PA+ +A
Sbjct: 73 RMMDKLRACIVANYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPSRSSSPANQRA 130
>gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2
[Homo sapiens]
Length = 676
Score = 27.7 bits (60), Expect = 8.2
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
Query: 133 FPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSS---LISNFPLLKA- 183
+P +K L+ G+ D L+ +L+RA +L VE+L SS L + F L A
Sbjct: 573 YPEAKKALEEKGRQILMKDNLIDEELARAGADPKDLEEKVEQLGSSLDTLQTRFARLLAE 632
Query: 184 -------LKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218
+K R+S L + K G KP AD + +A K
Sbjct: 633 YNATQMKMKQRLSQLESQVK----GGGDKPLADGEVPGDATK 670
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,821,120
Number of Sequences: 37866
Number of extensions: 303149
Number of successful extensions: 927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 884
Number of HSP's gapped (non-prelim): 35
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.