Guide to the Human Genome
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Search of human proteins with 24308336

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24308336 hypothetical protein LOC84553 [Homo sapiens]
         (409 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24308336 hypothetical protein LOC84553 [Homo sapiens]              861   0.0  
gi|5729937 metaxin 2 [Homo sapiens]                                    67   2e-11
gi|38569475 metaxin 1 isoform 1 [Homo sapiens]                         50   5e-06
gi|148806867 metaxin 3 [Homo sapiens]                                  46   5e-05
gi|38569477 metaxin 1 isoform 2 [Homo sapiens]                         39   0.009
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    36   0.055
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]                      30   3.0  
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]                      30   3.0  
gi|38708299 solute carrier family 29 (nucleoside transporters), ...    30   5.2  
gi|42519916 forkhead box O3A [Homo sapiens]                            29   8.8  
gi|4503739 forkhead box O3A [Homo sapiens]                             29   8.8  

>gi|24308336 hypothetical protein LOC84553 [Homo sapiens]
          Length = 409

 Score =  861 bits (2224), Expect = 0.0
 Identities = 409/409 (100%), Positives = 409/409 (100%)

Query: 1   MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSD 60
           MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSD
Sbjct: 1   MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSD 60

Query: 61  PWWKKTLYLTGGALLAAAAYLLHELLVIRKQQEIDSKDAIILHQFARPNNGVPSLSPFCL 120
           PWWKKTLYLTGGALLAAAAYLLHELLVIRKQQEIDSKDAIILHQFARPNNGVPSLSPFCL
Sbjct: 61  PWWKKTLYLTGGALLAAAAYLLHELLVIRKQQEIDSKDAIILHQFARPNNGVPSLSPFCL 120

Query: 121 KMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNHEKVSGTEFIIDFLEEKLGVNLNKNLG 180
           KMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNHEKVSGTEFIIDFLEEKLGVNLNKNLG
Sbjct: 121 KMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNHEKVSGTEFIIDFLEEKLGVNLNKNLG 180

Query: 181 PHERAISRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCHITKG 240
           PHERAISRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCHITKG
Sbjct: 181 PHERAISRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCHITKG 240

Query: 241 IVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAM 300
           IVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAM
Sbjct: 241 IVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAM 300

Query: 301 WTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLD 360
           WTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLD
Sbjct: 301 WTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLD 360

Query: 361 FSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMDDYTDHEQCK 409
           FSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMDDYTDHEQCK
Sbjct: 361 FSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMDDYTDHEQCK 409


>gi|5729937 metaxin 2 [Homo sapiens]
          Length = 263

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 54/218 (24%), Positives = 104/218 (47%), Gaps = 7/218 (3%)

Query: 120 LKMETYLRMADLPYQNYFGGK---LSAQGKMPWIEYNHEKVSGTEFIIDFLEEKLGVNLN 176
           L ++ +L+M +LP +         +S  GK+P+I   ++ VS    I+ F++ K G +L+
Sbjct: 42  LAVQAFLQMCNLPIKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAK-GHSLS 100

Query: 177 KNLGPHERAISRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCH 236
             L   ++A  +A  ++V         Y QW D      ++     G P+   L  ++ +
Sbjct: 101 DGLEEVQKAEMKAYMELVNNMLLTAELYLQWCDEAT-VGEITHARYGSPYPWPLNHILAY 159

Query: 237 ITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHL 296
             +  VKR+M   G G+ + +++   +++  ++L+  LG + Y    + + LDA VFGHL
Sbjct: 160 QKQWEVKRKMKAIGWGKKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHL 219

Query: 297 AQAMWT-LPGTRPERLIKGELINLAMYCERIRRKFWPE 333
              + T L        +K    NL  +C RI + ++ +
Sbjct: 220 YTILTTQLTNDELSEKVK-NYSNLLAFCRRIEQHYFED 256


>gi|38569475 metaxin 1 isoform 1 [Homo sapiens]
          Length = 466

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 57/230 (24%), Positives = 98/230 (42%), Gaps = 9/230 (3%)

Query: 111 GVPSLSPFCLKMETYLRMADLPYQNYFGGK--LSAQGKMPWIEYNHEKVSGTEFIIDFLE 168
           G+PS+    L + TY R    P + +       S  G +P +  +H +V      I    
Sbjct: 164 GLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHL 223

Query: 169 EKLGVNLNKNLGPHERAISRAVTKMVEEHFYWTLAYCQWVDNLNE---TRKMLSLSGGGP 225
            K   N + +L   + A + A   ++EE     L +  W+D  N    TRK  + +   P
Sbjct: 224 RKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFP 283

Query: 226 FSNLL--RWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGP 283
            +  L  R    ++ +  +    H        E+E+Y    + +  L+  LG +K+  G 
Sbjct: 284 LNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGD 343

Query: 284 KLSTLDATVFGHLAQAMWT-LPGTRPERLIKGELINLAMYCERIRRKFWP 332
             ++LDA VF +LA  +   LP  + +  ++G L NL  YC  I   ++P
Sbjct: 344 APASLDAFVFSYLALLLQAKLPSGKLQVHLRG-LHNLCAYCTHILSLYFP 392


>gi|148806867 metaxin 3 [Homo sapiens]
          Length = 312

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 58/235 (24%), Positives = 103/235 (43%), Gaps = 22/235 (9%)

Query: 111 GVPSLSPFCLKMETYLRMADLPYQ-----NYFGGKLSAQGKMPWIEYNHEKVSGTEFIID 165
           G+PS+    L +  Y + +  P +     N + G   ++G +P +    + VS    I++
Sbjct: 15  GLPSVHSESLVVMAYAKFSGAPLKVNVIDNTWRG---SRGDVPILTTEDDMVSQPAKILN 71

Query: 166 FLEEKLGVNLNKNLGPHERAISRAVTKMVEEHFYWTLAYCQWVDNLNE---TRKMLSLSG 222
           FL  K   N +  L   + A + A   ++EE     + +  WV++ N    T+   +   
Sbjct: 72  FLR-KQKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYFTVTKPWFASQI 130

Query: 223 GGPFSNLLRWVVCHITKGIVKREMHGHGIG-----RFSEEEIYMLMEKDMRSLAGLLGDK 277
             P S +L      ++KG + R +   G       R  E +IY   ++ +  L+  LG  
Sbjct: 131 PFPLSLILPG---RMSKGALNRILLTRGQPPLYHLREVEAQIYRDAKECLNLLSNRLGTS 187

Query: 278 KYIMGPKLSTLDATVFGHLAQAMWT-LPGTRPERLIKGELINLAMYCERIRRKFW 331
           ++  G   STLDA VFG LA       P  + +  +K +L NL  +C+ I   ++
Sbjct: 188 QFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLK-QLSNLCRFCDDILSSYF 241


>gi|38569477 metaxin 1 isoform 2 [Homo sapiens]
          Length = 435

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)

Query: 256 EEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWT-LPGTRPERLIKG 314
           E+E+Y    + +  L+  LG +K+  G   ++LDA VF +LA  +   LP  + +  ++G
Sbjct: 285 EKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRG 344

Query: 315 ELINLAMYCERIRRKFWP 332
            L NL  YC  I   ++P
Sbjct: 345 -LHNLCAYCTHILSLYFP 361


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
            sapiens]
          Length = 2715

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 27/131 (20%)

Query: 252  GRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQ--AMWTLPGTRPE 309
            G++SEEE          S +G+ GD    +G +L    A     L Q   +++      +
Sbjct: 2046 GKYSEEE-------SKSSTSGITGD----IGDELQEARAPTIAQLLQEKTLYSFSEWPKD 2094

Query: 310  RLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLDFSFYSRTET 369
            R+I   L N+   C  + +  WP            S++        TP+L  S  SRT  
Sbjct: 2095 RVIINRLDNI---CHVVLKGKWPS-----------SQQYEPSGTLPTPVLTSSAGSRTSL 2140

Query: 370  FEDEGAENSFS 380
             E E AE+SFS
Sbjct: 2141 SEPEAAEHSFS 2151


>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
          Length = 520

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 12/69 (17%)

Query: 333 EWHHDDDNTIYESEESSEGSKTHTPLLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSL 392
           EW + D+N +   EE  E +  + P             EDE AEN   +   T+    S 
Sbjct: 24  EWLYGDENEVERPEE--ENASANPP----------SGIEDETAENGVPKPKVTETEDDSD 71

Query: 393 FDSDVDMDD 401
            DSD D DD
Sbjct: 72  SDSDDDEDD 80


>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
          Length = 588

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 12/69 (17%)

Query: 333 EWHHDDDNTIYESEESSEGSKTHTPLLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSL 392
           EW + D+N +   EE  E +  + P             EDE AEN   +   T+    S 
Sbjct: 24  EWLYGDENEVERPEE--ENASANPP----------SGIEDETAENGVPKPKVTETEDDSD 71

Query: 393 FDSDVDMDD 401
            DSD D DD
Sbjct: 72  SDSDDDEDD 80


>gi|38708299 solute carrier family 29 (nucleoside transporters),
           member 2 [Homo sapiens]
          Length = 456

 Score = 29.6 bits (65), Expect = 5.2
 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 10/129 (7%)

Query: 51  GGIMAGLGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQEIDSKDAIILHQFARPNN 110
           G +   LG+ P    TL+L+G  L    A L    +++     +D++ +  L  F  P  
Sbjct: 146 GSLFGQLGTMPSTYSTLFLSGQGLAGIFAAL---AMLLSMASGVDAETS-ALGYFITPCV 201

Query: 111 GVPSLSPFCLKMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNHEKVSGTEFIIDFLEEK 170
           G+       + +  YL +  L +  Y+    S+Q +   +E   E +   E  I    +K
Sbjct: 202 GI------LMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAELLQSDENGIPSSPQK 255

Query: 171 LGVNLNKNL 179
           + + L+ +L
Sbjct: 256 VALTLDLDL 264


>gi|42519916 forkhead box O3A [Homo sapiens]
          Length = 673

 Score = 28.9 bits (63), Expect = 8.8
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 345 SEESSEGSKTHTPLLDFSFYSRTETFEDEGAENS-FSRTPDTDFTGHSLFDSDVDMDDYT 403
           SE SS GS  H      S     +T  D  + +S +S + +    GH  F SD+D+D + 
Sbjct: 560 SESSSLGSAKHQQQSPVS--QSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFN 617

Query: 404 DHEQC 408
              +C
Sbjct: 618 GSLEC 622


>gi|4503739 forkhead box O3A [Homo sapiens]
          Length = 673

 Score = 28.9 bits (63), Expect = 8.8
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 345 SEESSEGSKTHTPLLDFSFYSRTETFEDEGAENS-FSRTPDTDFTGHSLFDSDVDMDDYT 403
           SE SS GS  H      S     +T  D  + +S +S + +    GH  F SD+D+D + 
Sbjct: 560 SESSSLGSAKHQQQSPVS--QSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFN 617

Query: 404 DHEQC 408
              +C
Sbjct: 618 GSLEC 622


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,445,129
Number of Sequences: 37866
Number of extensions: 735636
Number of successful extensions: 1443
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1436
Number of HSP's gapped (non-prelim): 11
length of query: 409
length of database: 18,247,518
effective HSP length: 105
effective length of query: 304
effective length of database: 14,271,588
effective search space: 4338562752
effective search space used: 4338562752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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