BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24308013 peptidase (mitochondrial processing) alpha [Homo sapiens] (525 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24308013 peptidase (mitochondrial processing) alpha [Homo sap... 1051 0.0 gi|94538354 mitochondrial processing peptidase beta subunit prec... 191 1e-48 gi|46593007 ubiquinol-cytochrome c reductase core protein I [Hom... 166 6e-41 gi|50592988 ubiquinol-cytochrome c reductase core protein II [Ho... 139 6e-33 gi|156071452 nardilysin isoform b [Homo sapiens] 41 0.003 gi|156071450 nardilysin isoform a [Homo sapiens] 41 0.003 gi|155969707 insulin-degrading enzyme [Homo sapiens] 40 0.007 gi|226492499 septin 12 isoform 1 [Homo sapiens] 31 3.2 gi|226492421 septin 12 isoform 2 [Homo sapiens] 31 3.2 gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho... 30 5.4 gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [H... 30 5.4 gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Ho... 30 5.4 gi|21314671 transient receptor potential cation channel, subfami... 30 7.1 gi|4501869 acyl-Coenzyme A oxidase 2 [Homo sapiens] 29 9.2 >gi|24308013 peptidase (mitochondrial processing) alpha [Homo sapiens] Length = 525 Score = 1051 bits (2719), Expect = 0.0 Identities = 525/525 (100%), Positives = 525/525 (100%) Query: 1 MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVD 60 MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVD Sbjct: 1 MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVD 60 Query: 61 GQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSST 120 GQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSST Sbjct: 61 GQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSST 120 Query: 121 ARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEE 180 ARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEE Sbjct: 121 ARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEE 180 Query: 181 VEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHS 240 VEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHS Sbjct: 181 VEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHS 240 Query: 241 YLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKL 300 YLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKL Sbjct: 241 YLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKL 300 Query: 301 ERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMF 360 ERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMF Sbjct: 301 ERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMF 360 Query: 361 SRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVD 420 SRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVD Sbjct: 361 SRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVD 420 Query: 421 TVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRV 480 TVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRV Sbjct: 421 TVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRV 480 Query: 481 ASKMLRGKPAVAALGDLTDLPTYEHIQTALSSKDGRLPRTYRLFR 525 ASKMLRGKPAVAALGDLTDLPTYEHIQTALSSKDGRLPRTYRLFR Sbjct: 481 ASKMLRGKPAVAALGDLTDLPTYEHIQTALSSKDGRLPRTYRLFR 525 >gi|94538354 mitochondrial processing peptidase beta subunit precursor [Homo sapiens] Length = 489 Score = 191 bits (485), Expect = 1e-48 Identities = 135/445 (30%), Positives = 233/445 (52%), Gaps = 21/445 (4%) Query: 66 ETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDS 125 ET+VT L++GLRVAS++ CTVG+ I++GSRYE + +G AHFLE +AF T + S Sbjct: 57 ETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKK-RS 115 Query: 126 KDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTR 185 + ++ L +E G + TSR+ T+Y A SK L V +LAD++ L + E+E R Sbjct: 116 QLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERER 175 Query: 186 MAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNY 245 + E+++ + + + ++ + +H AY+ +G PTEN+ I+R+ L Y+ + Sbjct: 176 GVILREMQE--VETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTH 233 Query: 246 YTPDRMVLAGV-GVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDM 304 Y R+VLA GV H+ L+D A K+ G E + ++TG ++ D Sbjct: 234 YKGPRIVLAAAGGVSHDELLDLA-KFHFGDSLCTHKGEIPAL--PPCKFTGSEIRVRDDK 290 Query: 305 SNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLY 364 L H+ + +E+ + D I V N ++G S GG G + S+L Sbjct: 291 M----------PLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDR-SFGG-GMNLSSKL- 337 Query: 365 LNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVDTVEL 424 + + ++ S++ SY DTGL ++ + V +M+ ++ KE++ + +V E+ Sbjct: 338 AQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEV 397 Query: 425 ERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIRNVKPEDVKRVASKM 484 RA+ L + +++ L+ I ED+GRQ+L R EL I V E ++ V +K Sbjct: 398 ARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKY 457 Query: 485 LRGK-PAVAALGDLTDLPTYEHIQT 508 + + PA+AA+G + LP ++ I++ Sbjct: 458 IYNRSPAIAAVGPIKQLPDFKQIRS 482 >gi|46593007 ubiquinol-cytochrome c reductase core protein I [Homo sapiens] Length = 480 Score = 166 bits (419), Expect = 6e-41 Identities = 134/456 (29%), Positives = 219/456 (48%), Gaps = 38/456 (8%) Query: 66 ETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDS 125 ET+V+ LDNGLRVAS+ CTVG+ I+ GSR+E + +G +FLE LAF T Sbjct: 47 ETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPG 106 Query: 126 KDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTR 185 + +E G + ++R+ T Y + A SK L V LL D+V L D ++E R Sbjct: 107 -SALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKER 165 Query: 186 MAVQFELE--DLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHSYLR 243 + E++ D ++R ++ +H A++ + P+ENV K++R L YL Sbjct: 166 DVILREMQENDASMR----DVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLS 221 Query: 244 NYYTPDRMVLAGV-GVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLER 302 +Y RMVLA GVEH+ L+D A+K+L G+ W AE + ++TG Sbjct: 222 THYKAPRMVLAAAGGVEHQQLLDLAQKHLGGI--PWTYAEDAVPTLTPCRFTG------- 272 Query: 303 DMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMG------GGGSFSAGGPG 356 S + +P H+ + +E + D + V N ++G GGG + Sbjct: 273 --SEIRHRDDALP-FAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLA 329 Query: 357 KGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMG 416 G V N+ + S Y +TGLL H D ++ +M+ ++ +++ + Sbjct: 330 SGA-------VANKLCQSFQTFSI--CYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLC 380 Query: 417 GTVDTVELERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLP-HELCTLIRNVKPE 475 + E+ R K L + L+ +L+ + ED+GR +L T R++P E + I V Sbjct: 381 TSATESEVARGKNILRNALVSHLDGTTPVCEDIGRSLL-TYGRRIPLAEWESRIAEVDAS 439 Query: 476 DVKRVASKMLRGK-PAVAALGDLTDLPTYEHIQTAL 510 V+ + SK + + PAVA G + LP Y I++ + Sbjct: 440 VVREICSKYIYDQCPAVAGYGPIEQLPDYNRIRSGM 475 >gi|50592988 ubiquinol-cytochrome c reductase core protein II [Homo sapiens] Length = 453 Score = 139 bits (350), Expect = 6e-33 Identities = 116/479 (24%), Positives = 204/479 (42%), Gaps = 35/479 (7%) Query: 29 AYRRFSSGGAYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFC 88 ++ RF S P + ++ G P + + + T L NGL +AS + Sbjct: 9 SFSRFYSLKVAPKVKATAAPAGAPP---------QPQDLEFTKLPNGLVIASLENYSPVS 59 Query: 89 TVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDT 148 +G+ I +GSRYE G H L +L S T + S +I +E GG +R+ Sbjct: 60 RIGLFIKAGSRYEDFSNLGTTHLL-RLTSSLTTKGASSFKITRGIEAVGGKLSVTATREN 118 Query: 149 TMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELEDLNLRPDPEPLLTEM 208 Y V +D ++ L +V P EV + Q +++ +P+ + E Sbjct: 119 MAYTVECLRGDVDILMEFLLNVTTAPEFRRWEV--ADLQPQLKIDKAVAFQNPQTHVIEN 176 Query: 209 IHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCAR 268 +H AAYR N + +CP + K+ E LH +++N++T RM L G+GV H L A Sbjct: 177 LHAAAYR-NALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAE 235 Query: 269 KYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDMSNVSLGPTPIPELTHIMVGLESCS 328 ++L + + + A Y GG + + S L H ES Sbjct: 236 QFL-------NMRGGLGLSGAKANYRGGEIREQNGDS-----------LVHAAFVAESAV 277 Query: 329 FLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTG 388 + F+VL ++G G G S L+ V ++ ++++ SY D+G Sbjct: 278 AGSAEANAFSVLQHVLGAGPHVKR---GSNTTSHLHQAVAKATQQPFDVSAFNASYSDSG 334 Query: 389 LLCIHASADPRQVREMVEIITKEF-ILMGGTVDTVELERAKTQLTSMLMMNLESRPVIFE 447 L I+ + ++++ + + G + +++ AK +L + +M++ES E Sbjct: 335 LFGIYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLE 394 Query: 448 DVGRQVLATRSRKLPHELCTLIRNVKPEDVKRVASKMLRGKPAVAALGDLTDLPTYEHI 506 +VG Q L S P + I +V D+ A K + G+ ++AA G+L P + + Sbjct: 395 EVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL 453 >gi|156071452 nardilysin isoform b [Homo sapiens] Length = 1151 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/102 (22%), Positives = 45/102 (44%) Query: 92 ILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMY 151 + + GS + L G+AHFLE + F + ++ ++ L+KHGG + T + T++ Sbjct: 215 LCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVF 274 Query: 152 AVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELE 193 K + A + P + + ++ AV E + Sbjct: 275 QFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQ 316 >gi|156071450 nardilysin isoform a [Homo sapiens] Length = 1219 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/102 (22%), Positives = 45/102 (44%) Query: 92 ILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMY 151 + + GS + L G+AHFLE + F + ++ ++ L+KHGG + T + T++ Sbjct: 283 LCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVF 342 Query: 152 AVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELE 193 K + A + P + + ++ AV E + Sbjct: 343 QFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQ 384 >gi|155969707 insulin-degrading enzyme [Homo sapiens] Length = 1019 Score = 39.7 bits (91), Expect = 0.007 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 2/123 (1%) Query: 58 TVDGQEKFETKVTTLDNGLRVAS-QNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLA 116 T ++K E + L NG++V + + + ++ GS + ++G++HF E + Sbjct: 55 TKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHML 114 Query: 117 FSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRL 176 F T ++ ++E L +H G + TS + T Y + L+ + A L P L Sbjct: 115 FLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCP-L 173 Query: 177 TDE 179 DE Sbjct: 174 FDE 176 >gi|226492499 septin 12 isoform 1 [Homo sapiens] Length = 312 Score = 30.8 bits (68), Expect = 3.2 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 7/50 (14%) Query: 233 INREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAE 282 IN ++L+S LR DR+ A VG + EHLV+ + +LG + WG E Sbjct: 186 INDKILNSKLR-----DRIPFAVVGADQEHLVN--GRCVLGRKTKWGIIE 228 >gi|226492421 septin 12 isoform 2 [Homo sapiens] Length = 358 Score = 30.8 bits (68), Expect = 3.2 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 7/50 (14%) Query: 233 INREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAE 282 IN ++L+S LR DR+ A VG + EHLV+ + +LG + WG E Sbjct: 232 INDKILNSKLR-----DRIPFAVVGADQEHLVN--GRCVLGRKTKWGIIE 274 >gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo sapiens] Length = 864 Score = 30.0 bits (66), Expect = 5.4 Identities = 17/68 (25%), Positives = 33/68 (48%) Query: 178 DEEVEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREV 237 DE ++ R A++ + ++L + D L +M YRE L + PT+ + I + Sbjct: 97 DEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAI 156 Query: 238 LHSYLRNY 245 + L++Y Sbjct: 157 AYHLLKDY 164 >gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [Homo sapiens] Length = 429 Score = 30.0 bits (66), Expect = 5.4 Identities = 17/68 (25%), Positives = 33/68 (48%) Query: 178 DEEVEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREV 237 DE ++ R A++ + ++L + D L +M YRE L + PT+ + I + Sbjct: 97 DEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAI 156 Query: 238 LHSYLRNY 245 + L++Y Sbjct: 157 AYHLLKDY 164 >gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Homo sapiens] Length = 311 Score = 30.0 bits (66), Expect = 5.4 Identities = 17/68 (25%), Positives = 33/68 (48%) Query: 178 DEEVEMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREV 237 DE ++ R A++ + ++L + D L +M YRE L + PT+ + I + Sbjct: 97 DEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAI 156 Query: 238 LHSYLRNY 245 + L++Y Sbjct: 157 AYHLLKDY 164 >gi|21314671 transient receptor potential cation channel, subfamily M, member 4 [Homo sapiens] Length = 1214 Score = 29.6 bits (65), Expect = 7.1 Identities = 15/28 (53%), Positives = 18/28 (64%), Gaps = 5/28 (17%) Query: 343 MMGGGGSFSAGGPGKGMFS-----RLYL 365 + GGGGS ++GGPG G S RLYL Sbjct: 833 LSGGGGSLASGGPGPGHASLSQRLRLYL 860 >gi|4501869 acyl-Coenzyme A oxidase 2 [Homo sapiens] Length = 681 Score = 29.3 bits (64), Expect = 9.2 Identities = 17/42 (40%), Positives = 21/42 (50%) Query: 91 GILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLT 132 GIL NSG +LSG + + A+ R KD ILLT Sbjct: 583 GILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLT 624 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,936,556 Number of Sequences: 37866 Number of extensions: 915246 Number of successful extensions: 2563 Number of sequences better than 10.0: 14 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 2537 Number of HSP's gapped (non-prelim): 15 length of query: 525 length of database: 18,247,518 effective HSP length: 107 effective length of query: 418 effective length of database: 14,195,856 effective search space: 5933867808 effective search space used: 5933867808 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.