Search of human proteins with 24307989

Search of human proteins with 24307989

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24307989 nicotinamide mononucleotide adenylyltransferase 2
isoform 1 [Homo sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24307989 nicotinamide mononucleotide adenylyltransferase 2 is...   629   e-180
gi|25141325 nicotinamide mononucleotide adenylyltransferase 2 is...   572   e-163
gi|20070321 nicotinamide mononucleotide adenylyltransferase 1 [H...   179   3e-45
gi|30039706 nicotinamide mononucleotide adenylyltransferase 3 [H...    89   4e-18
gi|189083681 paired box gene 6 isoform a [Homo sapiens]                33   0.32 
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                  33   0.32 
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                  33   0.32 
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]            31   1.6  
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    30   2.7  
gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]           30   3.5  
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof...    28   7.8  
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof...    28   7.8  
gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo sapiens]    28   7.8  

>gi|24307989 nicotinamide mononucleotide adenylyltransferase 2
           isoform 1 [Homo sapiens]
          Length = 307

 Score =  629 bits (1621), Expect = e-180
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL 60
           MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
Sbjct: 1   MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL 60

Query: 61  VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP 120
           VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
Sbjct: 61  VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP 120

Query: 121 SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA 180
           SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
Sbjct: 121 SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA 180

Query: 181 NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI 240
           NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI
Sbjct: 181 NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI 240

Query: 241 MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ 300
           MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ
Sbjct: 241 MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ 300

Query: 301 LYINASG 307
           LYINASG
Sbjct: 301 LYINASG 307


>gi|25141325 nicotinamide mononucleotide adenylyltransferase 2
           isoform 2 [Homo sapiens]
          Length = 302

 Score =  572 bits (1474), Expect = e-163
 Identities = 279/283 (98%), Positives = 281/283 (99%)

Query: 25  IQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDP 84
           + + ERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDP
Sbjct: 20  VTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDP 79

Query: 85  WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVA 144
           WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVA
Sbjct: 80  WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVA 139

Query: 145 TKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLL 204
           TKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLL
Sbjct: 140 TKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLL 199

Query: 205 ESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHP 264
           ESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHP
Sbjct: 200 ESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHP 259

Query: 265 MSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG 307
           MSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG
Sbjct: 260 MSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG 302


>gi|20070321 nicotinamide mononucleotide adenylyltransferase 1 [Homo
           sapiens]
          Length = 279

 Score =  179 bits (454), Expect = 3e-45
 Identities = 103/307 (33%), Positives = 165/307 (53%), Gaps = 50/307 (16%)

Query: 1   MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL 60
           M  + KT V+LLACGSFNPIT  H+++FE A+DY++ TGR+ V+ GI+SPV D+Y K+GL
Sbjct: 1   MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGL 60

Query: 61  VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP 120
           + + HR+IM +LA +NS W+ VD WE  Q  W+ T  VL HH++ ++       S+ +  
Sbjct: 61  IPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLE------ASDCDHQ 114

Query: 121 SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA 180
             +P + +P  +                                       ++T   +++
Sbjct: 115 QNSPTLERPGRK--------------------------------------RKWTETQDSS 136

Query: 181 NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI 240
              ++    +   ++ LLCG+DLLESF +P LW   D+  IV ++G++ V R   D  + 
Sbjct: 137 QKKSLEPKTKAVPKVKLLCGADLLESFAVPNLWKSEDITQIVANYGLICVTRAGNDAQKF 196

Query: 241 MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVI-DYILKS 299
           +  S +L K+++NI VV + I +    +SSTK R AL+ G    + YL   ++ +YI K 
Sbjct: 197 IYESDVLWKHRSNIHVVNEWIAND---ISSTKIRRALRRGQS--IRYLVPDLVQEYIEKH 251

Query: 300 QLYINAS 306
            LY + S
Sbjct: 252 NLYSSES 258


>gi|30039706 nicotinamide mononucleotide adenylyltransferase 3 [Homo
           sapiens]
          Length = 215

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 81/265 (30%), Positives = 110/265 (41%), Gaps = 69/265 (26%)

Query: 43  VIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHH 102
           VI GI+SPV+D+YGK+ L +S HR+ M +LA+Q SDWIRVDPWE  Q  W  T  VL HH
Sbjct: 4   VIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHH 63

Query: 103 RDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSR 162
              + R                    PQ E P        + + P A   L        +
Sbjct: 64  HSKLLR------------------SPPQMEGPD---HGKALFSTPAAVPEL--------K 94

Query: 163 ICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIV 222
           + C    ++ F    +  NL      +EI            +E F               
Sbjct: 95  LLCGADVLKTF----QTPNLWKDAHIQEI------------VEKF--------------- 123

Query: 223 GDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDG 282
              G+V V R   D    +  S ILR +++NI + K+ + +    +S+T  R AL  G G
Sbjct: 124 ---GLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNE---ISATYIRRAL--GQG 175

Query: 283 HVVDYL-SQPVIDYILKSQLYINAS 306
             V YL    VI YI    LY   S
Sbjct: 176 QSVKYLIPDAVITYIKDHGLYTKGS 200


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 17/60 (28%), Positives = 27/60 (45%)

Query: 118 NTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVD 177
           NTPS  P+         QPI Q +   +  T+  +LG+   +L+      PP+  FT  +
Sbjct: 280 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN 339


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 17/60 (28%), Positives = 27/60 (45%)

Query: 118 NTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVD 177
           NTPS  P+         QPI Q +   +  T+  +LG+   +L+      PP+  FT  +
Sbjct: 294 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN 353


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 17/60 (28%), Positives = 27/60 (45%)

Query: 118 NTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVD 177
           NTPS  P+         QPI Q +   +  T+  +LG+   +L+      PP+  FT  +
Sbjct: 280 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN 339


>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
          Length = 511

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 11/85 (12%)

Query: 92  WQTTC-SVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATK--PT 148
           WQ TC   ++    +M      ++  + TP+ TPV G PQ     P+ + SNV  K   T
Sbjct: 225 WQETCVDAIKVPEKIMN-----MIEEIKTPASTPVSGTPQ---ASPMIERSNVVRKDYDT 276

Query: 149 AAKILGKVGESLSRICCVRPPVERF 173
            +K   K+  + S      P ++ F
Sbjct: 277 LSKCSPKMPPAPSGRAYTSPLIDMF 301


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 104  DLMKRVTG--CILSNVNTPSMTPVIGQPQNETPQPIYQNS 141
            D+M  V+G    +SN  T S+   I QPQ  TP PI   S
Sbjct: 1025 DIMAAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPS 1064


>gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]
          Length = 267

 Score = 29.6 bits (65), Expect = 3.5
 Identities = 13/33 (39%), Positives = 18/33 (54%)

Query: 85  WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNV 117
           W+ YQ  W    SVL HH   +K+V   +L N+
Sbjct: 228 WKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNI 260


>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform
           b [Homo sapiens]
          Length = 867

 Score = 28.5 bits (62), Expect = 7.8
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 46  GIVSPVH--DSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWE---CYQDTWQTTCSVLE 100
           G+V  +H  D +GK  LV+   R     L   N  ++RVD  +     +D    T  + E
Sbjct: 266 GVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKE 325

Query: 101 HHRDLM 106
           H +D++
Sbjct: 326 HDQDVL 331


>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform
           a [Homo sapiens]
          Length = 1011

 Score = 28.5 bits (62), Expect = 7.8
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 46  GIVSPVH--DSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWE---CYQDTWQTTCSVLE 100
           G+V  +H  D +GK  LV+   R     L   N  ++RVD  +     +D    T  + E
Sbjct: 410 GVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKE 469

Query: 101 HHRDLM 106
           H +D++
Sbjct: 470 HDQDVL 475


>gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo sapiens]
          Length = 411

 Score = 28.5 bits (62), Expect = 7.8
 Identities = 11/26 (42%), Positives = 19/26 (73%), Gaps = 1/26 (3%)

Query: 202 DLLESFCIPGLWNEADMEVIVGDFGI 227
           D+L+    PG WN+ DM +++G+FG+
Sbjct: 237 DILQPVAGPGHWNDPDM-LLIGNFGL 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,509,598
Number of Sequences: 37866
Number of extensions: 495845
Number of successful extensions: 994
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 983
Number of HSP's gapped (non-prelim): 15
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.