Search of human proteins with 24307907

Search of human proteins with 24307907

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24307907 plasminogen activator inhibitor type 1, member 2
isoform a precursor [Homo sapiens]
         (398 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   790   0.0  
gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   781   0.0  
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   781   0.0  
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   781   0.0  
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]          295   4e-80
gi|170295807 neuroserpin precursor [Homo sapiens]                     234   8e-62
gi|4826904 neuroserpin precursor [Homo sapiens]                       234   8e-62
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   211   7e-55
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   189   3e-48
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   188   8e-48
gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]   187   2e-47
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   181   1e-45
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   181   1e-45
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   176   3e-44
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   176   3e-44
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   171   8e-43
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   171   8e-43
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   170   2e-42
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   163   2e-40
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   163   2e-40
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   162   6e-40
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   161   1e-39
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   158   9e-39
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   155   6e-38
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ...   147   1e-35
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a...   147   1e-35
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   144   2e-34
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   143   3e-34
gi|73858566 heparin cofactor II precursor [Homo sapiens]              142   4e-34
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (...   138   8e-33

>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  790 bits (2040), Expect = 0.0
 Identities = 398/398 (100%), Positives = 398/398 (100%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360
           QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA
Sbjct: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360

Query: 361 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 361 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398


>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  781 bits (2016), Expect = 0.0
 Identities = 396/398 (99%), Positives = 396/398 (99%), Gaps = 1/398 (0%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 13  MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 72

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 73  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 132

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 133 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 192

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 193 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 252

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 253 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 312

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360
           QTDLKEPLKVLGITDMFDSSKANFAKIT  SENLHVSHILQKAKIEVSEDGTKASAATTA
Sbjct: 313 QTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVSEDGTKASAATTA 371

Query: 361 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 372 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  781 bits (2016), Expect = 0.0
 Identities = 396/398 (99%), Positives = 396/398 (99%), Gaps = 1/398 (0%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360
           QTDLKEPLKVLGITDMFDSSKANFAKIT  SENLHVSHILQKAKIEVSEDGTKASAATTA
Sbjct: 301 QTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVSEDGTKASAATTA 359

Query: 361 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 360 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  781 bits (2016), Expect = 0.0
 Identities = 396/398 (99%), Positives = 396/398 (99%), Gaps = 1/398 (0%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360
           QTDLKEPLKVLGITDMFDSSKANFAKIT  SENLHVSHILQKAKIEVSEDGTKASAATTA
Sbjct: 301 QTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVSEDGTKASAATTA 359

Query: 361 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 360 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
          Length = 402

 Score =  295 bits (756), Expect = 4e-80
 Identities = 157/380 (41%), Positives = 234/380 (61%), Gaps = 4/380 (1%)

Query: 21  HFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMV 80
           H  P  +  L S+ G++VF Q+ ++    N+V SP+G+ASVL MLQL   G T++Q+   
Sbjct: 25  HHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA 84

Query: 81  MRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138
           M + ++  G+   L+ + K ++   NKD ++  +A+FV+   ++   F+     +F+  V
Sbjct: 85  MGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTV 144

Query: 139 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 198
           + V+F +   A   IN WVK  T+ MI NLL    +D  LTRLVLVNA+YF G WK+ F 
Sbjct: 145 KQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQ-LTRLVLVNALYFNGQWKTPFP 203

Query: 199 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 258
             +T +R F  +DG +  VPM+AQ + F     + P+  +Y+ +ELPYHG+++SM IA P
Sbjct: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAP 263

Query: 259 TESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 318
            E   PLSA+   +S + I  W   M      ++LPKF+   + DL++PL+ LG+TDMF 
Sbjct: 264 YEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323

Query: 319 SSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFL 378
             +A+F  + +  E LHV+  LQK KIEV+E GT AS++T  I+ AR +P   I+DRPFL
Sbjct: 324 QFQADFTSL-SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFL 382

Query: 379 FFIRHNPTGAVLFMGQINKP 398
           F +RHNPTG VLFMGQ+ +P
Sbjct: 383 FVVRHNPTGTVLFMGQVMEP 402


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  234 bits (598), Expect = 8e-62
 Identities = 131/379 (34%), Positives = 222/379 (58%), Gaps = 12/379 (3%)

Query: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82

Query: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142

Query: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201

Query: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260

Query: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319

Query: 322 ANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLF 379
           AN   ++   E + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F
Sbjct: 320 ANLTGLSDNKE-IFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFF 378

Query: 380 FIRHNPTGAVLFMGQINKP 398
            IR+  TG +LFMG++  P
Sbjct: 379 LIRNRRTGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  234 bits (598), Expect = 8e-62
 Identities = 131/379 (34%), Positives = 222/379 (58%), Gaps = 12/379 (3%)

Query: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82

Query: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142

Query: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201

Query: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260

Query: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319

Query: 322 ANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLF 379
           AN   ++   E + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F
Sbjct: 320 ANLTGLSDNKE-IFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFF 378

Query: 380 FIRHNPTGAVLFMGQINKP 398
            IR+  TG +LFMG++  P
Sbjct: 379 LIRNRRTGTILFMGRVMHP 397


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  211 bits (538), Expect = 7e-55
 Identities = 123/355 (34%), Positives = 205/355 (57%), Gaps = 10/355 (2%)

Query: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK---ILKKINKAIVSKKNK 105
           DNI+ SP GI  VL M+QLGA G+ ++Q+   ++      G+   +LK    AI  KK +
Sbjct: 43  DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQE 102

Query: 106 DIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMI 165
               +ANA++++    ++  ++  NK+ FQ  ++ V+F+D  +  + I+ WV+ +T   I
Sbjct: 103 FTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKI 162

Query: 166 DNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSV 225
            ++ S +   G LTRLVLVNA+YFKG WK +F+ E+T+   F   +G + ++PM+  L  
Sbjct: 163 KDMFSGEEF-GPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221

Query: 226 FRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMV 285
            + G  S  + L Y  +EL Y G+  S++I LP E    +  +   I+ + I  W+S M 
Sbjct: 222 TKYGYFS-ESSLNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQ 279

Query: 286 PKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKI 345
            + V++ LP+F    + D K+ L  L IT++F S   + + IT  SE ++VS + QK   
Sbjct: 280 EEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSE-VYVSQVTQKVFF 337

Query: 346 EVSEDGTKASAATTAIL--IARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           E++EDG++A+ +T   +  I   +   FI + PFLF ++HNPT ++LFMG++  P
Sbjct: 338 EINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  189 bits (481), Expect = 3e-48
 Identities = 115/358 (32%), Positives = 202/358 (56%), Gaps = 16/358 (4%)

Query: 50  NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKD--- 106
           N+  SP  ++  L M+ +GA G T  Q+A ++ +  +G G  + +  ++++++ NK    
Sbjct: 26  NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQ 85

Query: 107 -IVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKNETRDM 164
            ++ +AN +F + + +    F    +  +Q E+  ++F          IN WV  +T   
Sbjct: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145

Query: 165 IDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLS 224
           I  LLSP  +D  LTRLVLVNAVYF+G W  +F  ENT++R F  +  +   V M+ + S
Sbjct: 146 IAELLSPGSVDP-LTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204

Query: 225 VFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSW--MS 282
            F+    +   +++   + LPY G+ ++M+I LP E +T L  +   ++ +    W  + 
Sbjct: 205 TFK---KTYIGEIFTQILVLPYVGKELNMIIMLPDE-TTDLRTVEKELTYEKFVEWTRLD 260

Query: 283 IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQK 342
           +M  + V+V LP+F      D++  L+ LG+TD F+  KA+F+ ++    +L +S ++ K
Sbjct: 261 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS--QTDLSLSKVVHK 318

Query: 343 AKIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           + +EV+E+GT+A+AAT AI++ R +   P F  D PFLFFI+H+ T  +LF G+ + P
Sbjct: 319 SFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  188 bits (477), Expect = 8e-48
 Identities = 129/387 (33%), Positives = 202/387 (52%), Gaps = 23/387 (5%)

Query: 27  LEELGS-NT--GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83
           +E+L S NT   + +F  + ++ P  NI ISP  I+S + M+ LG  G T  QL+    +
Sbjct: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60

Query: 84  G-VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 142
             V  V    + +N  I  +    I+ +AN ++ +        F+   +  +  ++ +V+
Sbjct: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120

Query: 143 FEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 201
           F+  +  A  +IN WVK +T   I  LL+  ++D  +T+LVLVNA+YFKG WK +F  E 
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDN-MTKLVLVNAIYFKGNWKDKFMKEA 179

Query: 202 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE- 260
           T    F         V M+ Q   F  G      DL    +ELPY GE +SM+I LP + 
Sbjct: 180 TTNAPFRLNKKDRKTVKMMYQKKKFAYGYIE---DLKCRVLELPYQGEELSMVILLPDDI 236

Query: 261 --SSTPLSAIIPHISTKTIDSWMSIMVPKR-----VQVILPKFTAVAQTDLKEPLKVLGI 313
              ST L  I   ++ + +  W     P+      V V LP+F       L   L  LG+
Sbjct: 237 EDESTGLKKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293

Query: 314 TDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPW--F 371
            D+F+SSKA+ + ++ G+ ++ +S I+ K+ +EV+E+GT+A+AAT  I       P   F
Sbjct: 294 QDLFNSSKADLSGMS-GARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENF 352

Query: 372 IVDRPFLFFIRHNPTGAVLFMGQINKP 398
             D PFLFFIRHN +G++LF+G+ + P
Sbjct: 353 TADHPFLFFIRHNSSGSILFLGRFSSP 379


>gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]
          Length = 424

 Score =  187 bits (474), Expect = 2e-47
 Identities = 126/401 (31%), Positives = 193/401 (48%), Gaps = 12/401 (2%)

Query: 5   LPLFLLASVTLPSICSHFNPLSLEE---LGSNTGIQVFNQIVKSRPHDNIVISPHGIASV 61
           +P FL+      S C   N    E    L +   + ++  +   R   N VISP G++  
Sbjct: 1   MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60

Query: 62  LGMLQLGADGRTKKQLAMVMRYGVNG--VGKILKKINKAIVSKKNKDIVTVANAVFVKNA 119
           L +LQ GA+G T +QLA  + Y V+   V   L  +   + +      + +A ++FV+  
Sbjct: 61  LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120

Query: 120 SEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSP-----DLI 174
           + +   FV          +   +  +P S     +     ET     +   P     + +
Sbjct: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSE-GPGGWPWEQV 179

Query: 175 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP 234
                +LVLV+ + F+G W+ RF   +T+   F  A G   QVPM+ Q +    G     
Sbjct: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239

Query: 235 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP 294
                  +ELPY G ++S+ + LP +  TPLS I PH++  TI  W + +   R+ V LP
Sbjct: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299

Query: 295 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKA 354
           +F    Q +LK  L   G+TD+FD  KAN   I +G +  +VS  + KAKIEV E+GTKA
Sbjct: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGI-SGQDGFYVSEAIHKAKIEVLEEGTKA 358

Query: 355 SAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQI 395
           S AT  +L+ RS  P F  DRPF++F+R   TG  +F  +I
Sbjct: 359 SGATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  181 bits (459), Expect = 1e-45
 Identities = 115/363 (31%), Positives = 194/363 (53%), Gaps = 18/363 (4%)

Query: 48  HDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV------NGVGKILKKINKAIVS 101
           +DNI +SP  I++   M +LGA   T +QL  V ++        + +     K+N  +  
Sbjct: 105 NDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYR 164

Query: 102 KKNKDIVTV-ANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKN 159
           K NK    V AN +F   +      +   ++ V+  +++ ++F++ A    + IN WV N
Sbjct: 165 KANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSN 224

Query: 160 ETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPM 219
           +T   I +++  + I+  LT LVLVN +YFKGLWKS+F PENT+K  F  ADG+S    M
Sbjct: 225 KTEGRITDVIPSEAINE-LTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASM 283

Query: 220 LAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDS 279
           + Q   FR    +    +    +ELP+ G+ I+M++ LP    + L+ +   ++ + +  
Sbjct: 284 MYQEGKFRYRRVAEGTQV----LELPFKGDDITMVLILPKPEKS-LAKVEKELTPEVLQE 338

Query: 280 WMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITT-GSENLHVSH 338
           W+  +    + V +P+F       LKE L+ +G+ D+F   K+    I   G ++L+VS 
Sbjct: 339 WLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSD 398

Query: 339 ILQKAKIEVSEDGTKASAATTAILIARSSPP---WFIVDRPFLFFIRHNPTGAVLFMGQI 395
              KA +EV+E+G++A+A+T  ++  RS  P    F  +RPFL FIR  P   ++FMG++
Sbjct: 399 AFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRV 458

Query: 396 NKP 398
             P
Sbjct: 459 ANP 461


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  181 bits (459), Expect = 1e-45
 Identities = 127/396 (32%), Positives = 207/396 (52%), Gaps = 31/396 (7%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMR--- 82
           SL E  +     +F Q  KS+  +NI  SP  I S LGM+ LGA   T +Q++ V+    
Sbjct: 3   SLSEANTKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61

Query: 83  -----------YGVNGVGKILKKINKAIVS-KKNKDI--VTVANAVFVKNASEIEVPFVT 128
                      Y V+  G +  +  K +    K+ D   + +AN +F +   +    ++ 
Sbjct: 62  VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLD 121

Query: 129 RNKDVFQCEVRNVNFED-PASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAV 187
             K  +Q  V + +F + P  +   IN+WV+++T + I NL  PD   G  T LVLVNA+
Sbjct: 122 AIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLF-PDGTIGNDTTLVLVNAI 180

Query: 188 YFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYH 247
           YFKG W+++F+ ENTK+  F         V M+ Q + F   + +   D+    +E+PY 
Sbjct: 181 YFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSF---NFALLEDVQAKVLEIPYK 237

Query: 248 GESISMLIALPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLK 305
           G+ +SM++ LP E    L  +   ++ + +  W S+  M    V + LP+F      DLK
Sbjct: 238 GKDLSMIVLLPNEID-GLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLK 296

Query: 306 EPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIAR 365
           + L+ +G+ ++F+   A+ + + T S  L VS +L KA +EV+E+G +A+AAT  +++  
Sbjct: 297 DTLRTMGMVNIFNGD-ADLSGM-TWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVEL 354

Query: 366 SSPPW---FIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           SSP     F  + PFLFFIR N T ++LF G+ + P
Sbjct: 355 SSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  176 bits (447), Expect = 3e-44
 Identities = 129/397 (32%), Positives = 206/397 (51%), Gaps = 33/397 (8%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMR--- 82
           SL E  +     +F Q  KS+  +NI  SP  I S LGM+ LGA   T +Q+  V+    
Sbjct: 3   SLSEANTKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61

Query: 83  -----------YGVNGVGKILKKINKAIVS-KKNKDI--VTVANAVFVKNASEIEVPFVT 128
                      Y V+  G +  +  K +    K+ D   + +AN +F +        ++ 
Sbjct: 62  VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLD 121

Query: 129 RNKDVFQCEVRNVNFED-PASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAV 187
             K  +Q  V +V+F + P  +   IN+WV+++T + I NL+ P+   G  T LVLVNA+
Sbjct: 122 AIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLI-PEGNIGSNTTLVLVNAI 180

Query: 188 YFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYH 247
           YFKG W+ +F  E+TK+  F         + M+ Q + F   S     D+    +E+PY 
Sbjct: 181 YFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASL---EDVQAKVLEIPYK 237

Query: 248 GESISMLIALPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLK 305
           G+ +SM++ LP E    L  +   ++ + +  W S+  M   RV + LP+F      DLK
Sbjct: 238 GKDLSMIVLLPNEID-GLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLK 296

Query: 306 EPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIAR 365
           + L+ +G+ D+F+   A+ + + TGS  L +S +L KA +EV+E+G +A+AA TA++   
Sbjct: 297 DTLRTMGMVDIFNGD-ADLSGM-TGSRGLVLSGVLHKAFVEVTEEGAEAAAA-TAVVGFG 353

Query: 366 SSP----PWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           SSP      F  + PFLFFIR N T ++LF G+ + P
Sbjct: 354 SSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  176 bits (446), Expect = 3e-44
 Identities = 116/386 (30%), Positives = 195/386 (50%), Gaps = 29/386 (7%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYG----------- 84
           + VF ++  +   DNI  S   +   L M+ LGA G T++QL  V+ +            
Sbjct: 13  LDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFK 72

Query: 85  ----VNGVGKILKKINKAIVSKKNKD---IVTVANAVFVKNASEIEVPFVTRNKDVFQCE 137
                +  G+I  +           D    +++AN ++          +++ ++  +Q  
Sbjct: 73  DSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQAR 132

Query: 138 VRNVNFEDPASAC-DSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSR 196
           ++ V+FE        +INAWV+N+T   + NL     ID     +VLVNA+YFKG W+++
Sbjct: 133 LQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSV-MVLVNAIYFKGQWQNK 191

Query: 197 FQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIA 256
           FQ   T K  F  ++GK+  V M+ Q+  F+      P       +ELPY    +SM+I 
Sbjct: 192 FQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ---MQVLELPYVNNKLSMIIL 248

Query: 257 LPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVLGIT 314
           LP   +  L  I   +++ T   W S   M+ + V+V LP+F    + +L   LK LG+T
Sbjct: 249 LPVGIAN-LKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVT 307

Query: 315 DMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFI 372
           D+F+  KA+ + ++  ++ L++S  + K+ ++VSE+GT+A+AAT   +  +S P    F 
Sbjct: 308 DLFNQVKADLSGMSP-TKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFK 366

Query: 373 VDRPFLFFIRHNPTGAVLFMGQINKP 398
            + PFLFFIRH  T  +LF G++  P
Sbjct: 367 ANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  171 bits (434), Expect = 8e-43
 Identities = 113/376 (30%), Positives = 194/376 (51%), Gaps = 13/376 (3%)

Query: 29  ELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVM-RYGVNG 87
           E      I +F  + +     N+  SP  I+S L M+ +GA G T  Q++  +  Y    
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD 65

Query: 88  VGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPA 147
           + +  + +   +     + ++  AN +F +   +    F    +  +Q E+  ++F +  
Sbjct: 66  IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDT 125

Query: 148 SACDS-INAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRT 206
             C   IN WV  +T   I  +L    +D  LT+LVLVNA+YFKG W  +F  + T+   
Sbjct: 126 EECRKHINDWVAEKTEGKISEVLDAGTVDP-LTKLVLVNAIYFKGKWNEQFDRKYTRGML 184

Query: 207 FVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLS 266
           F   + K   V M+ + + F+ G     +++    +ELPY  E +SM+I LP + +T L+
Sbjct: 185 FKTNEEKK-TVQMMFKEAKFKMGYA---DEVHTQVLELPYVEEELSMVILLP-DDNTDLA 239

Query: 267 AIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANF 324
            +   ++ +   +W +   +   +VQV LP+       DL+  L+ LG+ D FD +KA+F
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299

Query: 325 AKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIR 382
           + ++T  +N+ +S +  K  +EV+E+GT+A+AAT  +  +R S   P F  D PFLFFIR
Sbjct: 300 SGMST-EKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIR 358

Query: 383 HNPTGAVLFMGQINKP 398
           H+ T  +LF G+ + P
Sbjct: 359 HHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  171 bits (434), Expect = 8e-43
 Identities = 113/376 (30%), Positives = 194/376 (51%), Gaps = 13/376 (3%)

Query: 29  ELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVM-RYGVNG 87
           E      I +F  + +     N+  SP  I+S L M+ +GA G T  Q++  +  Y    
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD 65

Query: 88  VGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPA 147
           + +  + +   +     + ++  AN +F +   +    F    +  +Q E+  ++F +  
Sbjct: 66  IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDT 125

Query: 148 SACDS-INAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRT 206
             C   IN WV  +T   I  +L    +D  LT+LVLVNA+YFKG W  +F  + T+   
Sbjct: 126 EECRKHINDWVAEKTEGKISEVLDAGTVDP-LTKLVLVNAIYFKGKWNEQFDRKYTRGML 184

Query: 207 FVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLS 266
           F   + K   V M+ + + F+ G     +++    +ELPY  E +SM+I LP + +T L+
Sbjct: 185 FKTNEEKK-TVQMMFKEAKFKMGYA---DEVHTQVLELPYVEEELSMVILLP-DDNTDLA 239

Query: 267 AIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANF 324
            +   ++ +   +W +   +   +VQV LP+       DL+  L+ LG+ D FD +KA+F
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299

Query: 325 AKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIR 382
           + ++T  +N+ +S +  K  +EV+E+GT+A+AAT  +  +R S   P F  D PFLFFIR
Sbjct: 300 SGMST-EKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIR 358

Query: 383 HNPTGAVLFMGQINKP 398
           H+ T  +LF G+ + P
Sbjct: 359 HHKTNCILFCGRFSSP 374


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  170 bits (431), Expect = 2e-42
 Identities = 116/386 (30%), Positives = 191/386 (49%), Gaps = 24/386 (6%)

Query: 27  LEELGSNTG---IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83
           +E L + +G   I++   + +  P  N+  SP  I+S L M+ LGA G T  Q+A  +  
Sbjct: 1   METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60

Query: 84  GVN-----GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138
                       +L ++NKA      + ++  AN +F +   +    F       +  E+
Sbjct: 61  NTEEDIHRAFQSLLTEVNKA----GTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAEL 116

Query: 139 RNVNFEDPASACDS-INAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRF 197
           + ++F   A      IN WV  +T   I+ LL    ID   TRLVLVNA+YFKG W   F
Sbjct: 117 KELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAE-TRLVLVNAIYFKGKWNEPF 175

Query: 198 QPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIAL 257
               T++  F     +   V M+ Q + F+        ++    +ELPY  + +S+L+ L
Sbjct: 176 DETYTREMPFKINQEEQRPVQMMYQEATFKLAHVG---EVRAQLLELPYARKELSLLVLL 232

Query: 258 PTESSTPLSAIIPHISTKTIDSWMS--IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITD 315
           P +    LS +   ++ + + +W     M    V+V+LPKF      D++  L+ LGI D
Sbjct: 233 P-DDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVD 291

Query: 316 MFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIAR---SSPPWFI 372
            F   KA+ + ++    +L +S  + K+ +EV+E+GT+A+AA++  ++A     S P F 
Sbjct: 292 AFQQGKADLSAMSA-ERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFC 350

Query: 373 VDRPFLFFIRHNPTGAVLFMGQINKP 398
            D PFLFFIRHN   ++LF G+ + P
Sbjct: 351 ADHPFLFFIRHNRANSILFCGRFSSP 376


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  163 bits (413), Expect = 2e-40
 Identities = 112/409 (27%), Positives = 195/409 (47%), Gaps = 52/409 (12%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKI---- 91
           + +F  + K+ P  N+ +SP  I+S + M+ +G+ G T+ Q+A V+++   G   +    
Sbjct: 13  LNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMT 72

Query: 92  ----------------------------------LKKINKAIVSKKNKDIVTVANAVFVK 117
                                              + ++ AI +     ++   N +F +
Sbjct: 73  PENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGE 132

Query: 118 NASEIEVPFVTRNKDVFQCEVRNVNFEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDG 176
            ++     ++   +  +  E + V+F + A  A   IN+WVK +T+  I NLL    +DG
Sbjct: 133 KSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDG 192

Query: 177 VLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPND 236
             TR+VLVNAVYFKG WK+ F+ +      F     +   V M+        G      D
Sbjct: 193 D-TRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE---D 248

Query: 237 LWYNFIELPYHGESISMLIALPTES---STPLSAIIPHISTKTIDSWMSI--MVPKRVQV 291
           L    +ELPY G+ +SM + LP E    ST L  +   I+   ++ W S   M    V+V
Sbjct: 249 LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEV 307

Query: 292 ILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDG 351
            +P+F      +L+  L+ +G+ D F+  +ANF+ ++  ++ L +S +  +A ++V+E+G
Sbjct: 308 YIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERND-LFLSEVFHQAMVDVNEEG 366

Query: 352 TKASAATTAILIARSSP--PWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           T+A+A T  ++  R+    P F+ D PFLF I H  T  +LF G+ + P
Sbjct: 367 TEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  163 bits (413), Expect = 2e-40
 Identities = 112/409 (27%), Positives = 195/409 (47%), Gaps = 52/409 (12%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKI---- 91
           + +F  + K+ P  N+ +SP  I+S + M+ +G+ G T+ Q+A V+++   G   +    
Sbjct: 13  LNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMT 72

Query: 92  ----------------------------------LKKINKAIVSKKNKDIVTVANAVFVK 117
                                              + ++ AI +     ++   N +F +
Sbjct: 73  PENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGE 132

Query: 118 NASEIEVPFVTRNKDVFQCEVRNVNFEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDG 176
            ++     ++   +  +  E + V+F + A  A   IN+WVK +T+  I NLL    +DG
Sbjct: 133 KSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDG 192

Query: 177 VLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPND 236
             TR+VLVNAVYFKG WK+ F+ +      F     +   V M+        G      D
Sbjct: 193 D-TRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE---D 248

Query: 237 LWYNFIELPYHGESISMLIALPTES---STPLSAIIPHISTKTIDSWMSI--MVPKRVQV 291
           L    +ELPY G+ +SM + LP E    ST L  +   I+   ++ W S   M    V+V
Sbjct: 249 LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEV 307

Query: 292 ILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDG 351
            +P+F      +L+  L+ +G+ D F+  +ANF+ ++  ++ L +S +  +A ++V+E+G
Sbjct: 308 YIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERND-LFLSEVFHQAMVDVNEEG 366

Query: 352 TKASAATTAILIARSSP--PWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           T+A+A T  ++  R+    P F+ D PFLF I H  T  +LF G+ + P
Sbjct: 367 TEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  162 bits (409), Expect = 6e-40
 Identities = 120/394 (30%), Positives = 198/394 (50%), Gaps = 40/394 (10%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY----GVNGVGKI 91
           +++  ++ +S    NI  S   I++ L ++ LGA G T  Q+A V+++    GV    + 
Sbjct: 13  LELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPES 72

Query: 92  LKKINKAI------------------VSKKNKD-IVTVANAVFVKNASEIEVPFVTRNKD 132
            KK                       + K N D ++  ANA++ +        ++   K 
Sbjct: 73  EKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKT 132

Query: 133 VFQCEVRNVNFEDPASAC-DSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKG 191
            F  E + VNF + +      IN+WV+ +T   I NLL  D +D   TR++LVNA+YFKG
Sbjct: 133 YFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDST-TRMILVNALYFKG 191

Query: 192 LWKSRFQPENTKKRTFVAADGKSYQVPML---AQLSVFRCGSTSAPNDLWYNFIELPYHG 248
           +W+ +F  +NT ++ F   +  S  V M+    +L +F      A        ++L Y  
Sbjct: 192 IWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVG------LQLYYKS 245

Query: 249 ESISMLIALPTESSTPLSAIIPHISTKTIDSWMS--IMVPKRVQVILPKFTAVAQTDLKE 306
             +S+LI LP E    L  +   I+ + ++ W S  +M    VQ+ LPKF      DLK 
Sbjct: 246 RDLSLLILLP-EDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKS 304

Query: 307 PLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARS 366
            L  +G++D F  SKA+F+ +++ + NL +S++  KA +E++E GT+A+A + + +  R 
Sbjct: 305 TLSSMGMSDAFSQSKADFSGMSS-ARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRI 363

Query: 367 SPP--WFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
             P   F  + PFLFFIRHN T  +LF G++  P
Sbjct: 364 RVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  161 bits (407), Expect = 1e-39
 Identities = 119/400 (29%), Positives = 199/400 (49%), Gaps = 48/400 (12%)

Query: 38  VFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV------------ 85
           +F +I K   H NI  SP  +++ LGM++LGA   +  Q+  V+ +              
Sbjct: 15  LFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPC 74

Query: 86  --------------NGV-----GKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPF 126
                         +G+     G++L K+++     K    +++AN ++ +    I   +
Sbjct: 75  LKSNKQKAGSLNNESGLVSCYFGQLLSKLDRI----KTDYTLSIANRLYGEQEFPICQEY 130

Query: 127 VTRNKDVFQCEVRNVNFE-DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVN 185
           +      +   + +V+F+ +P  +   IN WV+ +++  I  L S D I+   T LVLVN
Sbjct: 131 LDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAE-TVLVLVN 189

Query: 186 AVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELP 245
           AVYFK  W++ F  ENT    F     ++  V M+ Q  ++R G      ++    +E+ 
Sbjct: 190 AVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFI---EEVKAQILEMR 246

Query: 246 YHGESISMLIALPTESSTPLSAIIP---HISTKTIDSWMSI--MVPKRVQVILPKFTAVA 300
           Y    +SM + LP+ S   L  +      I+ + + +W S   M  + V +  P+FT   
Sbjct: 247 YTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLED 306

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360
             DL   L+ +GITD+FD ++A+   I+  S NL++S I+ K  +EV E+GT+A+AAT A
Sbjct: 307 SYDLNSILQDMGITDIFDETRADLTGISP-SPNLYLSKIIHKTFVEVDENGTQAAAATGA 365

Query: 361 ILIARSSPPW--FIVDRPFLFFIRHNPTGAVLFMGQINKP 398
           ++  RS   W  F  + PFLFFIRHN T  +LF G++  P
Sbjct: 366 VVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  158 bits (399), Expect = 9e-39
 Identities = 107/381 (28%), Positives = 203/381 (53%), Gaps = 25/381 (6%)

Query: 30  LGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV---- 85
           L ++   +++ ++V   P  NI  SP  +++ L ML LGA   TK Q+   + + +    
Sbjct: 65  LNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTP 124

Query: 86  -NGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
            + + +  + +  ++        + + +A+FVK   +++  F+   K +++ EV + +F 
Sbjct: 125 ESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFS 184

Query: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGV--LTRLVLVNAVYFKGLWKSRFQPENT 202
           +P+ A   IN+ VK +T+  +      D+I G+  LT +VLVN ++FK  W+  F PE T
Sbjct: 185 NPSIAQARINSHVKKKTQGKV-----VDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYT 239

Query: 203 KKR-TFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTES 261
           +K   F+  +  +  VPM+ Q   F  G  +  N      +++ Y G++++  + LP++ 
Sbjct: 240 RKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCF---VLQMDYKGDAVAFFV-LPSKG 295

Query: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321
              +  +   +S +T+  W   +  + ++V +P+F+  A  +L+  L  +GI ++FD + 
Sbjct: 296 K--MRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN- 352

Query: 322 ANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARS--SPPWFIV--DRPF 377
           A+F+ I    ++L VS    KA ++VSE+GT+A+AATT   I RS   P +F V  +R F
Sbjct: 353 ADFSGIAK-RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 411

Query: 378 LFFIRHNPTGAVLFMGQINKP 398
           L  I +  T  +LF+G++  P
Sbjct: 412 LMMITNKATDGILFLGKVENP 432


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  155 bits (392), Expect = 6e-38
 Identities = 119/396 (30%), Positives = 187/396 (47%), Gaps = 30/396 (7%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV 85
           SL  + +  G  +F ++ K+    NI  SP GI + +GM+ LG  G T  QL  V     
Sbjct: 3   SLGAVSTRLGFDLFKELKKTND-GNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEK 61

Query: 86  NGVGKILKKINKAIV-----------------SKKNKDI-VTVANAVFVKNASEIEVPFV 127
                 +K   K ++                 SK   D  + + N +F +        ++
Sbjct: 62  ETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYL 121

Query: 128 TRNKDVFQCEVRNVNFEDPASAC-DSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNA 186
              +  +   +  V+F + A      IN+WV+++T + I +L  PD      T+LVLVN 
Sbjct: 122 DYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLF-PDGSISSSTKLVLVNM 180

Query: 187 VYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPY 246
           VYFKG W   F+ ENTK+  F      S  V M+ Q   F   S +   DL    + +PY
Sbjct: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSF---SFTFLEDLQAKILGIPY 237

Query: 247 HGESISMLIALPTESSTPLSAIIPHISTKTIDSWMS--IMVPKRVQVILPKFTAVAQTDL 304
               +SM + LP +    L  II  IS + +  W S   M  ++V + LP+F      DL
Sbjct: 238 KNNDLSMFVLLPNDID-GLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDL 296

Query: 305 KEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIA 364
           +  L  +G+ D F   KA+++ +++GS  L+    L  + + V+E+GT+A+AAT      
Sbjct: 297 EAVLAAMGMGDAFSEHKADYSGMSSGS-GLYAQKFLHSSFVAVTEEGTEAAAATGIGFTV 355

Query: 365 RSSPPWFIV--DRPFLFFIRHNPTGAVLFMGQINKP 398
            S+P    V  + PFLFFIRHN + ++LF G+ + P
Sbjct: 356 TSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  147 bits (372), Expect = 1e-35
 Identities = 110/375 (29%), Positives = 192/375 (51%), Gaps = 21/375 (5%)

Query: 32  SNTGIQVFNQIVKSRPHD-NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK 90
           SN G  +  +I  S  HD N+V SP G++  +  L LGA G T+ Q+   +        K
Sbjct: 80  SNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTK 137

Query: 91  --ILKKINKAIVSKKNKDI---VTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFED 145
             +L  + K +    ++++   +T  +  F+    +++  F   +K  F  E   +NF +
Sbjct: 138 PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN 197

Query: 146 PASACDSINAWVKNETRDMIDNLLSPDLIDGVL--TRLVLVNAVYFKGLWKSRFQPENTK 203
            + A   +N ++  ETR  I     P L D +   T+L+LV+ + FKG W + F P  T+
Sbjct: 198 ASQAKRLMNHYINKETRGKI-----PKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252

Query: 204 KRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESST 263
             TF     K+ +VPM+     F   +++   +   + ++LPY G + +ML+ L  +   
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKF---ASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGD 308

Query: 264 PLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKAN 323
            L A+  +++T  +++W+  M  + ++V  PKF    + ++ E L+ +GI  +F S  A+
Sbjct: 309 HL-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-SPFAD 366

Query: 324 FAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRH 383
            ++++    NL VS +LQ+  IEV E GT+A A   + + A S PP   VDRPF F I  
Sbjct: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426

Query: 384 NPTGAVLFMGQINKP 398
             +G +LF+G++  P
Sbjct: 427 ETSGMLLFLGRVVNP 441


>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  147 bits (372), Expect = 1e-35
 Identities = 110/375 (29%), Positives = 192/375 (51%), Gaps = 21/375 (5%)

Query: 32  SNTGIQVFNQIVKSRPHD-NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK 90
           SN G  +  +I  S  HD N+V SP G++  +  L LGA G T+ Q+   +        K
Sbjct: 80  SNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTK 137

Query: 91  --ILKKINKAIVSKKNKDI---VTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFED 145
             +L  + K +    ++++   +T  +  F+    +++  F   +K  F  E   +NF +
Sbjct: 138 PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN 197

Query: 146 PASACDSINAWVKNETRDMIDNLLSPDLIDGVL--TRLVLVNAVYFKGLWKSRFQPENTK 203
            + A   +N ++  ETR  I     P L D +   T+L+LV+ + FKG W + F P  T+
Sbjct: 198 ASQAKRLMNHYINKETRGKI-----PKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252

Query: 204 KRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESST 263
             TF     K+ +VPM+     F   +++   +   + ++LPY G + +ML+ L  +   
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKF---ASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGD 308

Query: 264 PLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKAN 323
            L A+  +++T  +++W+  M  + ++V  PKF    + ++ E L+ +GI  +F S  A+
Sbjct: 309 HL-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-SPFAD 366

Query: 324 FAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRH 383
            ++++    NL VS +LQ+  IEV E GT+A A   + + A S PP   VDRPF F I  
Sbjct: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426

Query: 384 NPTGAVLFMGQINKP 398
             +G +LF+G++  P
Sbjct: 427 ETSGMLLFLGRVVNP 441


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  144 bits (362), Expect = 2e-34
 Identities = 102/370 (27%), Positives = 186/370 (50%), Gaps = 24/370 (6%)

Query: 38  VFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG-----VGKIL 92
           ++  +V   P  NI ISP  I+  L ML LG  G T+ QL   + + +       + +  
Sbjct: 50  LYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGF 109

Query: 93  KKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS 152
           + +++          +T+ NA+F+  + E+   F    K  ++ EV  +NF+D A+A   
Sbjct: 110 QHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQ 169

Query: 153 INAWVKNETR----DMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFV 208
           IN++VKN+T+    D+   L SP +       LVLVN ++FKG W   F   +T++  F 
Sbjct: 170 INSYVKNKTQGKIVDLFSGLDSPAI-------LVLVNYIFFKGTWTQPFDLASTREENFY 222

Query: 209 AADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAI 268
             +    +VPM+ Q S     S     +L    +++ Y G   ++   LP +    ++ +
Sbjct: 223 VDETTVVKVPMMLQSSTI---SYLHDAELPCQLVQMNYVGNG-TVFFILPDKGK--MNTV 276

Query: 269 IPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKIT 328
           I  +S  TI+ W + +   +V + +PK T     DL + L+ +GI D+F +++ANF++IT
Sbjct: 277 IAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLF-TNQANFSRIT 335

Query: 329 TGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGA 388
             ++ L  S ++ KA ++++E+G   + +T   L   S P     ++PF+  I  + T +
Sbjct: 336 QDAQ-LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWS 394

Query: 389 VLFMGQINKP 398
            LF+ ++  P
Sbjct: 395 SLFLARVMNP 404


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  143 bits (360), Expect = 3e-34
 Identities = 102/373 (27%), Positives = 193/373 (51%), Gaps = 30/373 (8%)

Query: 38  VFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN---------GV 88
           ++  +  + P  +I  SP  I+  L ML LGA   TK Q+   +   +          G 
Sbjct: 52  LYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGF 111

Query: 89  GKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPAS 148
            ++L+++N+     ++   +++ NA+F     +++  FV+  K ++  +    NF D A 
Sbjct: 112 QQLLQELNQP----RDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAG 167

Query: 149 ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFV 208
           A   IN +V  +T+  I +LL     + V+   ++VN ++FK  W++ F  + T+++ F 
Sbjct: 168 AMKQINDYVAKQTKGKIVDLLKNLDSNAVV---IMVNYIFFKAKWETSFNHKGTQEQDFY 224

Query: 209 AADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAI 268
                  +VPM+++   +         +L    + +PY G + ++ I LP+E    +  +
Sbjct: 225 VTSETVVRVPMMSREDQYHY---LLDRNLSCRVVGVPYQGNATALFI-LPSEGK--MQQV 278

Query: 269 IPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKIT 328
              +S KT+  W+ +   +++++ LPKF+      L++ L  LGI+++F +S A+ + I+
Sbjct: 279 ENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVF-TSHADLSGIS 337

Query: 329 TGSENLHVSHILQKAKIEVSEDGTKASAATTAILI---ARSSPPWFIVDRPFLFFIRHNP 385
             S N+ VS ++ KA +EV E GT+A+AAT  I     AR +    + +RPFL FI  N 
Sbjct: 338 NHS-NIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN- 395

Query: 386 TGAVLFMGQINKP 398
              +LF+G++N+P
Sbjct: 396 --NILFLGKVNRP 406


>gi|73858566 heparin cofactor II precursor [Homo sapiens]
          Length = 499

 Score =  142 bits (359), Expect = 4e-34
 Identities = 99/360 (27%), Positives = 183/360 (50%), Gaps = 22/360 (6%)

Query: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVM----------RYGVNGVGKILKKINKA 98
           DNI I+P GI++ +GM+ LG  G T +Q+  ++          +Y +  +  + +K+   
Sbjct: 149 DNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHR 208

Query: 99  IVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVK 158
           +  +     +   N ++++    I + F T+ ++ +  E +  +F DPA    + N  +K
Sbjct: 209 LFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFISKTNNHIMK 268

Query: 159 NETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVP 218
             T+ +I + L  + ID   T+++++N +YFKG W ++F  E T    F   + +  +V 
Sbjct: 269 L-TKGLIKDAL--ENIDPA-TQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVS 324

Query: 219 MLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTID 278
           M+     F   +     +L  + ++L Y G  ISMLI +P + S  +  +   ++ + ++
Sbjct: 325 MMQTKGNFLAANDQ---ELDCDILQLEYVG-GISMLIVVPHKMSG-MKTLEAQLTPRVVE 379

Query: 279 SWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSH 338
            W   M  +  +V+LPKF      +L E LK++GI  +FD +  N A I+   + + +  
Sbjct: 380 RWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKN-GNMAGIS--DQRIAIDL 436

Query: 339 ILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
              +  I V+E+GT+A+  TT   +  S+   F VDRPFLF I  + T  +LFMG++  P
Sbjct: 437 FKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFMGRVANP 496


>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  138 bits (348), Expect = 8e-33
 Identities = 107/389 (27%), Positives = 189/389 (48%), Gaps = 27/389 (6%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMR--- 82
           SL    +     +F ++  ++ + N+  S   + + L +++LGA   +  Q+  ++    
Sbjct: 3   SLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNT 62

Query: 83  ---YG-----VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVF 134
              YG      +G+   LK++   I +      +++ N +F +        ++   + ++
Sbjct: 63  ASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLY 122

Query: 135 QCEVRNVNFEDPASACD-SINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLW 193
             +V  V+F +       +IN WV+NET   I N++    I      +VLVNAVYFKG W
Sbjct: 123 DAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAV-MVLVNAVYFKGKW 181

Query: 194 KSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISM 253
           +S F    T    F +       V M+ Q   F       P+      +EL Y+G  I+M
Sbjct: 182 QSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPS---MKILELRYNG-GINM 237

Query: 254 LIALPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVL 311
            + LP      LS I   ++ + +  W +   M  K V+V  P+F      ++K+ L+ L
Sbjct: 238 YVLLPEND---LSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRAL 294

Query: 312 GITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--P 369
           G+ D+FD SKA+ + I +G   L++S ++ K+ IEV+E+GT+A+AAT + ++ +  P   
Sbjct: 295 GLKDIFDESKADLSGIASGG-RLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQST 353

Query: 370 WFIVDRPFLFFIRHNPTGAVLFMGQINKP 398
            F  D PFLF IR +    +LF G+++ P
Sbjct: 354 LFRADHPFLFVIRKD--DIILFSGKVSCP 380


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,548,143
Number of Sequences: 37866
Number of extensions: 525761
Number of successful extensions: 1397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1135
Number of HSP's gapped (non-prelim): 89
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.