Search of human proteins with 239788483

Search of human proteins with 239788483

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo
sapiens]
         (408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo sapi...   837   0.0  
gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo sapi...   724   0.0  
gi|40807366 PP3111 protein [Homo sapiens]                              85   1e-16
gi|31742496 dihydrouridine synthase 4-like [Homo sapiens]              77   2e-14
gi|8923374 dihydrouridine synthase 2-like, SMM1 homolog [Homo sa...    73   4e-13
gi|41350212 bromodomain containing 7 [Homo sapiens]                    30   3.9  
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]              29   6.7  
gi|55770836 saccharopine dehydrogenase (putative) [Homo sapiens]       29   6.7  
gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]       29   8.8  

>gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo
           sapiens]
          Length = 408

 Score =  837 bits (2162), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETELD 60
           MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETELD
Sbjct: 1   MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETELD 60

Query: 61  IRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIF 120
           IRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIF
Sbjct: 61  IRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIF 120

Query: 121 GVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVR 180
           GVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVR
Sbjct: 121 GVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVR 180

Query: 181 GMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYI 240
           GMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYI
Sbjct: 181 GMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYI 240

Query: 241 EECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKPWLFTEIKEQRHWDIS 300
           EECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKPWLFTEIKEQRHWDIS
Sbjct: 241 EECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKPWLFTEIKEQRHWDIS 300

Query: 301 SSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGLLERLPQRINERP 360
           SSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGLLERLPQRINERP
Sbjct: 301 SSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGLLERLPQRINERP 360

Query: 361 PYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK 408
           PYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK
Sbjct: 361 PYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK 408


>gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo
           sapiens]
          Length = 650

 Score =  724 bits (1870), Expect = 0.0
 Identities = 351/357 (98%), Positives = 353/357 (98%)

Query: 52  KTCRETELDIRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALL 111
           + C +  LDIRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALL
Sbjct: 294 RPCEKKRLDIRGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALL 353

Query: 112 KRHQCEDIFGVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNR 171
           KRHQCEDIFGVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNR
Sbjct: 354 KRHQCEDIFGVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNR 413

Query: 172 STKFQQIVRGMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRY 231
           STKFQQIVRGMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRY
Sbjct: 414 STKFQQIVRGMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRY 473

Query: 232 TKLADWQYIEECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKPWLFTEI 291
           TKLADWQYIEECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKPWLFTEI
Sbjct: 474 TKLADWQYIEECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKPWLFTEI 533

Query: 292 KEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGLLER 351
           KEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGLLER
Sbjct: 534 KEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGLLER 593

Query: 352 LPQRINERPPYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK 408
           LPQRINERPPYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK
Sbjct: 594 LPQRINERPPYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK 650



 Score =  121 bits (303), Expect = 1e-27
 Identities = 58/59 (98%), Positives = 59/59 (100%)

Query: 1  MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETEL 59
          MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETE+
Sbjct: 1  MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETEV 59


>gi|40807366 PP3111 protein [Homo sapiens]
          Length = 473

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 59/169 (34%), Positives = 97/169 (57%), Gaps = 10/169 (5%)

Query: 146 DFVDINVGCPIDLVYKKGG-GCALMNRSTKFQQIVRGMNQVLDVPLTVKIRTGVQERVNL 204
           D +D+N+GCP  ++ K+G  G  L +     Q+++   ++ L VP+T KIR  V   ++ 
Sbjct: 100 DAIDLNLGCP-QMIAKRGHYGAFLQDEWDLLQRMILLAHEKLSVPVTCKIR--VFPEIDK 156

Query: 205 AHRLLPELRDWGVALVTLHGRSREQR--YTKLADWQYIEECVQAASPMPLFGNGDILSFE 262
             R    L   G  L+T+HGR++EQ+   +  A W++I + V+ A  +P+F NG+I   +
Sbjct: 157 TVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHI-KAVRKAVAIPVFANGNIQCLQ 215

Query: 263 DANRAMQ-TGVTGIMIARGALLKPWLFTEIKEQRHWDISSSERLDILRD 310
           D  R ++ TGV G+M A G L  P LF E +    W++ + E LDI+R+
Sbjct: 216 DVERCLRDTGVQGVMSAEGNLHNPALF-EGRSPAVWEL-AEEYLDIVRE 262


>gi|31742496 dihydrouridine synthase 4-like [Homo sapiens]
          Length = 317

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 55/228 (24%), Positives = 108/228 (47%), Gaps = 6/228 (2%)

Query: 68  APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGA 127
           AP+     L FR + +++  D+    M V  + ++   +  +    +Q +    VQ    
Sbjct: 32  APMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAAN 91

Query: 128 FPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLD 187
               ++  A ++      + +DIN GCP      +G G  L+N+    Q +V+ +   ++
Sbjct: 92  DARLLSDAARIVCPYA--NGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVE 149

Query: 188 VP-LTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQA 246
            P  +V I+  + + +     L  +    GV+ +T+HGR+ E+R+  +  +  I + ++ 
Sbjct: 150 TPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPV-HYDSI-KIIKE 207

Query: 247 ASPMPLFGNGDILSFEDANRAMQ-TGVTGIMIARGALLKPWLFTEIKE 293
              +P+  NGDI S ++A    + TG  G+M+ARG L  P +F   +E
Sbjct: 208 NMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEE 255


>gi|8923374 dihydrouridine synthase 2-like, SMM1 homolog [Homo
           sapiens]
          Length = 493

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 68/251 (27%), Positives = 113/251 (45%), Gaps = 37/251 (14%)

Query: 64  KLYLAPLTTCGNLPFRRICKRFGADVT-CGE-----MAVCTNLLQGQMSE---------- 107
           KL LAP+   G LP R +   +GAD+  C E     M  C  ++   +S           
Sbjct: 13  KLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRV 72

Query: 108 -WALLKRHQCEDIFGVQLEGAFPDTMTKCAELLSRTVEVDF--VDINVGCPIDLVYKKGG 164
            +   +R Q   +F +    A      + A  ++R VE D   +D+N+GCP     K G 
Sbjct: 73  VFRTCEREQNRVVFQMGTSDA------ERALAVARLVENDVAGIDVNMGCPKQYSTKGGM 126

Query: 165 GCALMNRSTKFQQIVRGMNQVLDVPLTVKIR--TGVQERVNLAHRLLPELRDWGVALVTL 222
           G AL++   K ++I+  + +    P+T KIR    +++ ++L  R    +   G+A + +
Sbjct: 127 GAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKR----IERTGIAAIAV 182

Query: 223 HGRSREQRYTKLADWQYIEECVQAASPMPLFGNG----DILSFEDANRAMQ-TGVTGIMI 277
           HGR RE+R       + I+      S +P+  NG     I  + D     Q T  + +M+
Sbjct: 183 HGRKREERPQHPVSCEVIKAIADTLS-IPVIANGGSHDHIQQYSDIEDFRQATAASSVMV 241

Query: 278 ARGALLKPWLF 288
           AR A+  P +F
Sbjct: 242 ARAAMWNPSIF 252


>gi|41350212 bromodomain containing 7 [Homo sapiens]
          Length = 651

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 9/92 (9%)

Query: 289 TEIKEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGL 348
           TE++     D S+ +RL  L+  TN+G+     D++  E  ++ L E    L       L
Sbjct: 502 TEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEAEIFQKKLDETTRLLRE-----L 556

Query: 349 LERLPQRINERPP----YYLGRDYLETLMASQ 376
            E   +R++ RPP      LG  Y E  +A Q
Sbjct: 557 QEAQNERLSTRPPPNMICLLGPSYREMHLAEQ 588


>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
          Length = 3062

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 28/114 (24%), Positives = 57/114 (50%), Gaps = 12/114 (10%)

Query: 175  FQQIVRGMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRD-WGVALVTLHGRSREQRYTK 233
            FQ ++RG+   +D    +++   ++ ++ ++  + PELR  + +     HG   EQ   +
Sbjct: 1244 FQAVLRGL---IDYDTGIRL---LETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQ 1297

Query: 234  LADWQYIEECVQAASP--MPLFGNGDILSFEDANRAMQTGVTGIMIARGALLKP 285
            L +    +E + AASP  +P+    D L+      +M   V  I+++ G+L+ P
Sbjct: 1298 LKELSKAKEIISAASPTTIPVL---DALAQSMITESMAIKVLEILLSTGSLVIP 1348


>gi|55770836 saccharopine dehydrogenase (putative) [Homo sapiens]
          Length = 429

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 283 LKPWLFTEIKEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLE 335
           LKP      K +R W IS        R+   Y +   GSD   V +T+R+L E
Sbjct: 219 LKPVPLIGPKLKRRWPIS------YCRELKGYSIPFMGSDVSVVRRTQRYLYE 265


>gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]
          Length = 399

 Score = 28.9 bits (63), Expect = 8.8
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 5/53 (9%)

Query: 4  GTAEAPLENGGGGDSGAGALERGVAP-IKRQYLTTKEQFH----QFLEAKGQE 51
          G    P  NG GG++ A  L R  AP    Q    K  F+    QF  A GQE
Sbjct: 47 GVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQE 99


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,792,621
Number of Sequences: 37866
Number of extensions: 699880
Number of successful extensions: 1635
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1622
Number of HSP's gapped (non-prelim): 11
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.