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Search of human proteins with 239758082
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239758082 PREDICTED: similar to thyrotoxic periodic
paralysis susceptibility ion channel [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 876 0.0
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 859 0.0
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 818 0.0
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 818 0.0
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 818 0.0
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 613 e-176
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 547 e-156
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 547 e-156
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 482 e-136
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 482 e-136
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 390 e-108
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 383 e-106
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 376 e-104
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 366 e-101
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 338 7e-93
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 329 3e-90
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 325 5e-89
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 325 5e-89
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 325 5e-89
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 325 5e-89
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 325 5e-89
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 312 3e-85
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 312 3e-85
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 312 3e-85
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 281 1e-75
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 281 1e-75
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 281 1e-75
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 279 3e-75
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 187 2e-47
gi|7706363 map kinase phosphatase-like protein MK-STYX [Homo sap... 32 1.1
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 876 bits (2263), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM
Sbjct: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
Query: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR
Sbjct: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
Query: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
Sbjct: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
Sbjct: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
Sbjct: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
Query: 421 VLEQRPYRRGSEI 433
VLEQRPYRRGSEI
Sbjct: 421 VLEQRPYRRGSEI 433
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 859 bits (2220), Expect = 0.0
Identities = 426/433 (98%), Positives = 427/433 (98%)
Query: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
MTAASRANPYSIVS EEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNI FANM
Sbjct: 1 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
Query: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG+IFWVIAVAHGDLEPAEG GR
Sbjct: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEEC VAVFMVVAQSIVGCIIDSFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
Query: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
MAKMARPKKRA TLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
Sbjct: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
Sbjct: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
Sbjct: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
Query: 421 VLEQRPYRRGSEI 433
VLEQRPYRR SEI
Sbjct: 421 VLEQRPYRRESEI 433
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 818 bits (2113), Expect = 0.0
Identities = 406/433 (93%), Positives = 415/433 (95%), Gaps = 1/433 (0%)
Query: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
MTAASRANPYSIVS EEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNI FANM
Sbjct: 1 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 60
Query: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEG GR
Sbjct: 61 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 120
Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEEC VAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 180
Query: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
MAKM RPKKRA TLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 181 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 240
Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
GEYIPLDQIDIDVGFDKGLD FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 300
Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 301 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 359
Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 360 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 419
Query: 421 VLEQRPYRRGSEI 433
VLEQRPYRR SEI
Sbjct: 420 VLEQRPYRRESEI 432
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 818 bits (2113), Expect = 0.0
Identities = 406/433 (93%), Positives = 415/433 (95%), Gaps = 1/433 (0%)
Query: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
MTAASRANPYSIVS EEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNI FANM
Sbjct: 103 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 162
Query: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEG GR
Sbjct: 163 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 222
Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEEC VAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 223 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 282
Query: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
MAKM RPKKRA TLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 283 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 342
Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
GEYIPLDQIDIDVGFDKGLD FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 343 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 402
Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 403 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 461
Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 462 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 521
Query: 421 VLEQRPYRRGSEI 433
VLEQRPYRR SEI
Sbjct: 522 VLEQRPYRRESEI 534
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 818 bits (2113), Expect = 0.0
Identities = 406/433 (93%), Positives = 415/433 (95%), Gaps = 1/433 (0%)
Query: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
MTAASRANPYSIVS EEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNI FANM
Sbjct: 1 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 60
Query: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEG GR
Sbjct: 61 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 120
Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEEC VAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 180
Query: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
MAKM RPKKRA TLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 181 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 240
Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
GEYIPLDQIDIDVGFDKGLD FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 300
Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 301 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 359
Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 360 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 419
Query: 421 VLEQRPYRRGSEI 433
VLEQRPYRR SEI
Sbjct: 420 VLEQRPYRRESEI 432
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 613 bits (1581), Expect = e-176
Identities = 302/430 (70%), Positives = 355/430 (82%), Gaps = 9/430 (2%)
Query: 6 RANPYSIVSLEEDGLHLVTMSGANGFGNGK--VHTRRRCRNRFVKKNGQCNIAFANMDEK 63
R N YSIVS EEDG+ L TM+ ANGFGNGK VHTR++CR+RFVKK+G CN+ F N+ EK
Sbjct: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
Query: 64 SQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGRTPC 123
QRYLAD+FTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ A G+ C
Sbjct: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLD-ASKEGKA-C 122
Query: 124 VMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAK 183
V +V+ F AAFLFSIETQTTIGYG RCVT+EC +AVFMVV QSIVGCIID+F+IGA+MAK
Sbjct: 123 VSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAK 182
Query: 184 MARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEY 243
MA+PKKR TL+FSHNAV+A+RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K R+T EGEY
Sbjct: 183 MAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEY 242
Query: 244 IPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMV 303
IPLDQIDI+VGFD G+DRIFLVSPITI+HEIDE SPL+ +S+QD++ DFEIVVILEGMV
Sbjct: 243 IPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMV 302
Query: 304 EATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLV 363
EATAMTTQ RSSYLANEILWGHR+EPVLFEEK+ YK+DYS FHKTYEVP+TP CSA+DL
Sbjct: 303 EATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLA 362
Query: 364 ENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLE 423
E K++L +ANSFCYENE+A S++E+D +G + S D D D LE
Sbjct: 363 EKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPLE 417
Query: 424 QRPYRRGSEI 433
RP RR SEI
Sbjct: 418 PRPLRRESEI 427
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 547 bits (1409), Expect = e-156
Identities = 268/380 (70%), Positives = 315/380 (82%), Gaps = 22/380 (5%)
Query: 33 NGKVHT-RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAF 91
NG+ H RR+ RNRFVKKNGQCN+ FAN+ KSQRY+AD+FTTCVD RWRYML+IFS AF
Sbjct: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
Query: 92 LASWLLFGVIFWVIAVAHGDLE----------PAEGHGRT------PCVMQVHGFMAAFL 135
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
Query: 136 FSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLL 195
FS+ETQTTIGYG RCVTEEC +AV VV QSIVGC+IDSFMIG IMAKMARPKKRA TLL
Sbjct: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
Query: 196 FSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGF 255
FSH+AV+++RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
Query: 256 DKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSS 315
D GLDRIFLVSPI I+HEIDE SPL+G+ +++LE++DFEIVVILEGMVEATAMTTQARSS
Sbjct: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
Query: 316 YLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL-----P 370
YLA+EILWGHRFEPV+FEEK+ YK+DYS FHKTYEV TP CSA++L E+K + P
Sbjct: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
Query: 371 SANSFCYENELAFLSRDEED 390
++FCYENELA +S++EE+
Sbjct: 367 PPSAFCYENELALMSQEEEE 386
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 547 bits (1409), Expect = e-156
Identities = 268/380 (70%), Positives = 315/380 (82%), Gaps = 22/380 (5%)
Query: 33 NGKVHT-RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAF 91
NG+ H RR+ RNRFVKKNGQCN+ FAN+ KSQRY+AD+FTTCVD RWRYML+IFS AF
Sbjct: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
Query: 92 LASWLLFGVIFWVIAVAHGDLE----------PAEGHGRT------PCVMQVHGFMAAFL 135
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
Query: 136 FSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLL 195
FS+ETQTTIGYG RCVTEEC +AV VV QSIVGC+IDSFMIG IMAKMARPKKRA TLL
Sbjct: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
Query: 196 FSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGF 255
FSH+AV+++RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
Query: 256 DKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSS 315
D GLDRIFLVSPI I+HEIDE SPL+G+ +++LE++DFEIVVILEGMVEATAMTTQARSS
Sbjct: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
Query: 316 YLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL-----P 370
YLA+EILWGHRFEPV+FEEK+ YK+DYS FHKTYEV TP CSA++L E+K + P
Sbjct: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
Query: 371 SANSFCYENELAFLSRDEED 390
++FCYENELA +S++EE+
Sbjct: 367 PPSAFCYENELALMSQEEEE 386
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 482 bits (1241), Expect = e-136
Identities = 238/367 (64%), Positives = 284/367 (77%), Gaps = 11/367 (2%)
Query: 41 RCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGV 100
R R RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L+FS +FLASWLLFG+
Sbjct: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
Query: 101 IFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVF 160
FW+IA HGDL A PC V F+AAFLF++ETQT+IGYG+R VTEEC AV
Sbjct: 107 AFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
Query: 161 MVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRK 220
VV Q I GC++D+F++GA+MAKMA+PKKR TL+FS NAVVALRD +LCLMWRVGNLR+
Sbjct: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
Query: 221 SHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPL 280
SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G DRIFLVSPITI+HEID ASPL
Sbjct: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
Query: 281 FGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKI 340
+ + R +L DFE+VVILEGMVEATAMTTQ RSSYL E+LWGHRFEPVLF+ +QY++
Sbjct: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
Query: 341 DYSHFHKTYEVPSTPRCSAKDLVEN--------KFLLP-SANSFCYENELAFLSRDEEDE 391
DY HFH+TYEVP TP CSAK+L E K P S +FCYENELA EEDE
Sbjct: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
Query: 392 ADGDQDG 398
D ++G
Sbjct: 405 DDETEEG 411
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 482 bits (1241), Expect = e-136
Identities = 238/367 (64%), Positives = 284/367 (77%), Gaps = 11/367 (2%)
Query: 41 RCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGV 100
R R RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L+FS +FLASWLLFG+
Sbjct: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
Query: 101 IFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVF 160
FW+IA HGDL A PC V F+AAFLF++ETQT+IGYG+R VTEEC AV
Sbjct: 107 AFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
Query: 161 MVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRK 220
VV Q I GC++D+F++GA+MAKMA+PKKR TL+FS NAVVALRD +LCLMWRVGNLR+
Sbjct: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
Query: 221 SHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPL 280
SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G DRIFLVSPITI+HEID ASPL
Sbjct: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
Query: 281 FGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKI 340
+ + R +L DFE+VVILEGMVEATAMTTQ RSSYL E+LWGHRFEPVLF+ +QY++
Sbjct: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
Query: 341 DYSHFHKTYEVPSTPRCSAKDLVEN--------KFLLP-SANSFCYENELAFLSRDEEDE 391
DY HFH+TYEVP TP CSAK+L E K P S +FCYENELA EEDE
Sbjct: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
Query: 392 ADGDQDG 398
D ++G
Sbjct: 405 DDETEEG 411
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 390 bits (1002), Expect = e-108
Identities = 198/360 (55%), Positives = 264/360 (73%), Gaps = 7/360 (1%)
Query: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
RRR R R+V+K+G+CN+ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
Query: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158
G I+W+IA GDLE E TPCV ++GF+AAFLFSIET+TTIGYG R +T++C
Sbjct: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218
+ +++ Q+I+G ++++FM+G + K+++P KRA TL+FS +AVV+LRDG+LCLM+RVG+L
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
Query: 219 RKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEAS 278
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G DR+FLVSP+ I HEID AS
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
Query: 279 PLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
P + SR+ LE DDFEIVVILEGMVEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
Query: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDG 398
++DY+ FH+T+EVP TP CSA++L E L + + + L DE+ E +G +G
Sbjct: 316 EVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL-----DEKVEEEGAGEG 369
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 383 bits (983), Expect = e-106
Identities = 193/373 (51%), Positives = 268/373 (71%), Gaps = 11/373 (2%)
Query: 40 RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
++ R R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
Query: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
I+W+IA GDL+ PCV + GF++AFLFSIET+TTIGYG R +TE+C +
Sbjct: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
+++ Q+I+G I+++FM+G + K+++PKKRA TL+FS+NAV+++RD KLCLM+RVG+LR
Sbjct: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
SHIVEA +RA+LIK R T+EGE+IPL+Q DI+VGFD G DR+FLVSP+ I HEI++ SP
Sbjct: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
Query: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339
+ +S+ L ++FE+VVILEGMVEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
Query: 340 IDYSHFHKTYEVPSTPRCSAKDLVENK------FLLPSANSF--CYENEL-AFLSRDEED 390
+DY+ FH TYE +TP C AK+L E K LPS C E L A ++EED
Sbjct: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
Query: 391 EADGDQDGRSRDG 403
E G R G
Sbjct: 405 EPKGLGGSREARG 417
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 376 bits (966), Expect = e-104
Identities = 190/368 (51%), Positives = 274/368 (74%), Gaps = 6/368 (1%)
Query: 38 TRRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLL 97
T+R+ + R+V+K+G+CN+ N+ E + RYL D+FTT VD++WR+ LLIF + + +WL
Sbjct: 49 TKRKIQ-RYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106
Query: 98 FGVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLV 157
FG+I+W+IA GD++ E TPCV ++GF++AFLFSIET+TTIGYG R +T++C
Sbjct: 107 FGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPE 166
Query: 158 AVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGN 217
+ +++ QS++G I+++FM+G + K+++PKKRA TL+FS +AV+++RDGKLCLM+RVG+
Sbjct: 167 GIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGD 226
Query: 218 LRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
LR SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G DR+FLVSP+ I HEI++
Sbjct: 227 LRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQ 286
Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
SP + IS+ L ++ EIVVILEGMVEAT MT QARSSY+ +EILWG+RF PVL E
Sbjct: 287 SPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGF 346
Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDLVE--NKFLLPSANSFCYE-NELAFLSRDEEDEADG 394
Y++DY+ FH+TYE STP SAK+L E ++ LP + S + N+ A L +EE++
Sbjct: 347 YEVDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLE 405
Query: 395 DQDGRSRD 402
+Q R+ D
Sbjct: 406 EQTERNGD 413
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 366 bits (940), Expect = e-101
Identities = 171/325 (52%), Positives = 238/325 (73%), Gaps = 1/325 (0%)
Query: 40 RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
++ R RFV KNG+CN+ N+ ++ RYL+D+FTT VD++WR+ L IF L + +WL
Sbjct: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
Query: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
++WVIA GDL A TPCV V+ F +AFLF IET+ TIGYG R +T++C +
Sbjct: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
+ + QSI+G I+D+F+IG + KM++PKKRA TL+FS +AV+++RDGKL LM+RVGNLR
Sbjct: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
SH+V A +R +L+K R T EGE++PLDQ+++DVGF G D++FLVSP+TI H ID SP
Sbjct: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
Query: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339
+ +S++ ++T+ FEIVVILEG+VE T MT QAR+SY +E+LWGHRF PV+ E+ +K
Sbjct: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339
Query: 340 IDYSHFHKTYEVPSTPRCSAKDLVE 364
+DYS FH T+EVP TP S K+ E
Sbjct: 340 VDYSQFHATFEVP-TPPYSVKEQEE 363
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 338 bits (866), Expect = 7e-93
Identities = 171/331 (51%), Positives = 235/331 (70%), Gaps = 4/331 (1%)
Query: 40 RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
R+ R RFV K G CN+A N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
Query: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
+ +W+IA AHGDL P+EG PCV +H F +AFLFSIE Q TIG+G R VTEEC +A+
Sbjct: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
+++ Q+IVG +I++ M+G I K A+ +RA TL+FS +AV+ALR G+LC M RVG+LR
Sbjct: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
KS I+ A + Q+++ + EGE +PL Q+DI + G + IFLV+P+ I H ID SP
Sbjct: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
Query: 280 LFGISRQDL-ETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
L+ ++ DL D EI+VILEG+VE T +TTQAR+SYLA+EILWG RF P++ EE +Y
Sbjct: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
Query: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
+DYS F T +VP TP C+A+ L E+ LL
Sbjct: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 329 bits (843), Expect = 3e-90
Identities = 165/333 (49%), Positives = 232/333 (69%), Gaps = 10/333 (3%)
Query: 45 RFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
RF+ K+G CN+A N+ E+ R+L D+FTT VD++WR+ L+IF+++FL SWLLF +++W+
Sbjct: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
Query: 105 IAVAHGDLEP--------AEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECL 156
+A AHGD+ G T CV V F +AFLFSIE Q TIG+G R +TEEC
Sbjct: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
Query: 157 VAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVG 216
+A+ +++ Q+IVG II++ M+G I K A+ +RA TL+FS +AV+A+R+GKLC M+RVG
Sbjct: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
Query: 217 NLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDE 276
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V + IFLV+P+ I H ID+
Sbjct: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
Query: 277 ASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN 336
SPL+ IS DL D E++VILEG+VE T +TTQAR+SY+A EI WGHRF ++ EE+
Sbjct: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
Query: 337 QYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
Y +DYS F T +V + PRCSA++L E +L
Sbjct: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 325 bits (833), Expect = 5e-89
Identities = 161/327 (49%), Positives = 232/327 (70%), Gaps = 10/327 (3%)
Query: 37 HTRRRCRNRFVKKNGQCNIAFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
H+R+R R V K+G+CNI F N++ +S+ + D++TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 96 LLFGVIFWVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVT 152
FG++++ +A H DL P+ H TPCV ++G +AFLFS+ETQ TIGYG RCVT
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANH--TPCVENINGLTSAFLFSLETQVTIGYGFRCVT 131
Query: 153 EECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLM 212
E+C A+F+++ QSI+G II+SFM GAI+AK++RPKKRA T+ FS NAV++ R GKLCL+
Sbjct: 132 EQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLL 191
Query: 213 WRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILH 272
RV NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G + +F +SP+TI H
Sbjct: 192 IRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYH 251
Query: 273 EIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLF 332
ID SP F ++ + L DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 252 VIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVS 311
Query: 333 EEK-NQYKIDYSHFHKTYEVPSTPRCS 358
+ K +Y++D+ +F KT EV TP C+
Sbjct: 312 KTKEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 325 bits (833), Expect = 5e-89
Identities = 161/327 (49%), Positives = 232/327 (70%), Gaps = 10/327 (3%)
Query: 37 HTRRRCRNRFVKKNGQCNIAFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
H+R+R R V K+G+CNI F N++ +S+ + D++TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 96 LLFGVIFWVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVT 152
FG++++ +A H DL P+ H TPCV ++G +AFLFS+ETQ TIGYG RCVT
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANH--TPCVENINGLTSAFLFSLETQVTIGYGFRCVT 131
Query: 153 EECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLM 212
E+C A+F+++ QSI+G II+SFM GAI+AK++RPKKRA T+ FS NAV++ R GKLCL+
Sbjct: 132 EQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLL 191
Query: 213 WRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILH 272
RV NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G + +F +SP+TI H
Sbjct: 192 IRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYH 251
Query: 273 EIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLF 332
ID SP F ++ + L DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 252 VIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVS 311
Query: 333 EEK-NQYKIDYSHFHKTYEVPSTPRCS 358
+ K +Y++D+ +F KT EV TP C+
Sbjct: 312 KTKEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 325 bits (833), Expect = 5e-89
Identities = 161/327 (49%), Positives = 232/327 (70%), Gaps = 10/327 (3%)
Query: 37 HTRRRCRNRFVKKNGQCNIAFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
H+R+R R V K+G+CNI F N++ +S+ + D++TT +D++WRY + IF AFL SW
Sbjct: 35 HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 92
Query: 96 LLFGVIFWVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVT 152
FG++++ +A H DL P+ H TPCV ++G +AFLFS+ETQ TIGYG RCVT
Sbjct: 93 FFFGLLWYAVAYIHKDLPEFHPSANH--TPCVENINGLTSAFLFSLETQVTIGYGFRCVT 150
Query: 153 EECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLM 212
E+C A+F+++ QSI+G II+SFM GAI+AK++RPKKRA T+ FS NAV++ R GKLCL+
Sbjct: 151 EQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLL 210
Query: 213 WRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILH 272
RV NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G + +F +SP+TI H
Sbjct: 211 IRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYH 270
Query: 273 EIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLF 332
ID SP F ++ + L DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 271 VIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVS 330
Query: 333 EEK-NQYKIDYSHFHKTYEVPSTPRCS 358
+ K +Y++D+ +F KT EV TP C+
Sbjct: 331 KTKEGKYRVDFHNFSKTVEV-ETPHCA 356
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 325 bits (833), Expect = 5e-89
Identities = 161/327 (49%), Positives = 232/327 (70%), Gaps = 10/327 (3%)
Query: 37 HTRRRCRNRFVKKNGQCNIAFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
H+R+R R V K+G+CNI F N++ +S+ + D++TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 96 LLFGVIFWVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVT 152
FG++++ +A H DL P+ H TPCV ++G +AFLFS+ETQ TIGYG RCVT
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANH--TPCVENINGLTSAFLFSLETQVTIGYGFRCVT 131
Query: 153 EECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLM 212
E+C A+F+++ QSI+G II+SFM GAI+AK++RPKKRA T+ FS NAV++ R GKLCL+
Sbjct: 132 EQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLL 191
Query: 213 WRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILH 272
RV NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G + +F +SP+TI H
Sbjct: 192 IRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYH 251
Query: 273 EIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLF 332
ID SP F ++ + L DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 252 VIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVS 311
Query: 333 EEK-NQYKIDYSHFHKTYEVPSTPRCS 358
+ K +Y++D+ +F KT EV TP C+
Sbjct: 312 KTKEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 325 bits (833), Expect = 5e-89
Identities = 161/327 (49%), Positives = 232/327 (70%), Gaps = 10/327 (3%)
Query: 37 HTRRRCRNRFVKKNGQCNIAFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
H+R+R R V K+G+CNI F N++ +S+ + D++TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 96 LLFGVIFWVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVT 152
FG++++ +A H DL P+ H TPCV ++G +AFLFS+ETQ TIGYG RCVT
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANH--TPCVENINGLTSAFLFSLETQVTIGYGFRCVT 131
Query: 153 EECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLM 212
E+C A+F+++ QSI+G II+SFM GAI+AK++RPKKRA T+ FS NAV++ R GKLCL+
Sbjct: 132 EQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLL 191
Query: 213 WRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILH 272
RV NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G + +F +SP+TI H
Sbjct: 192 IRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYH 251
Query: 273 EIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLF 332
ID SP F ++ + L DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 252 VIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVS 311
Query: 333 EEK-NQYKIDYSHFHKTYEVPSTPRCS 358
+ K +Y++D+ +F KT EV TP C+
Sbjct: 312 KTKEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 312 bits (800), Expect = 3e-85
Identities = 162/325 (49%), Positives = 223/325 (68%), Gaps = 10/325 (3%)
Query: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
+RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158
G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218
V MV+ QSI+ CII++F+IGA +AKMA +KRA T+ FS+ A++ +RDGKLCLMWR+G+
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID
Sbjct: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260
Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++
Sbjct: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320
Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
YK++ F + EV P CSAK L
Sbjct: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 312 bits (800), Expect = 3e-85
Identities = 162/325 (49%), Positives = 223/325 (68%), Gaps = 10/325 (3%)
Query: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
+RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158
G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218
V MV+ QSI+ CII++F+IGA +AKMA +KRA T+ FS+ A++ +RDGKLCLMWR+G+
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID
Sbjct: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260
Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++
Sbjct: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320
Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
YK++ F + EV P CSAK L
Sbjct: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 312 bits (800), Expect = 3e-85
Identities = 162/325 (49%), Positives = 223/325 (68%), Gaps = 10/325 (3%)
Query: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
+RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158
G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218
V MV+ QSI+ CII++F+IGA +AKMA +KRA T+ FS+ A++ +RDGKLCLMWR+G+
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID
Sbjct: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260
Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++
Sbjct: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320
Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
YK++ F + EV P CSAK L
Sbjct: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 281 bits (718), Expect = 1e-75
Identities = 142/333 (42%), Positives = 214/333 (64%), Gaps = 11/333 (3%)
Query: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI+
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 103 WVIAVAHGDLEPAEG-HGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFM 161
+ IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEEC A+F+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
+VAQ ++ +I+ F+ G +AK+ARPKKRA T+ FSH AV+ ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
+++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
D+S F ++ +P C S K +E K+
Sbjct: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 281 bits (718), Expect = 1e-75
Identities = 142/333 (42%), Positives = 214/333 (64%), Gaps = 11/333 (3%)
Query: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI+
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 103 WVIAVAHGDLEPAEG-HGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFM 161
+ IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEEC A+F+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
+VAQ ++ +I+ F+ G +AK+ARPKKRA T+ FSH AV+ ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
+++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
D+S F ++ +P C S K +E K+
Sbjct: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 281 bits (718), Expect = 1e-75
Identities = 142/333 (42%), Positives = 214/333 (64%), Gaps = 11/333 (3%)
Query: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI+
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 103 WVIAVAHGDLEPAEG-HGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFM 161
+ IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEEC A+F+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
+VAQ ++ +I+ F+ G +AK+ARPKKRA T+ FSH AV+ ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
+++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
D+S F ++ +P C S K +E K+
Sbjct: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 279 bits (714), Expect = 3e-75
Identities = 142/315 (45%), Positives = 209/315 (66%), Gaps = 7/315 (2%)
Query: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
R R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LFGV++
Sbjct: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
Query: 103 WVIAVAHGDL---EPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
+++AVAHGDL +P H TPCV+QVH AFLFS+E+QTTIGYG R ++EEC +A+
Sbjct: 87 YLVAVAHGDLLELDPPANH--TPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAI 144
Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
+++AQ ++ I++ F+ G +AK+ARPKKRA T+ FS +AVVA +GK CLM RV N+R
Sbjct: 145 VLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMR 204
Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
KS ++ V +L++ T+EGE I L+Q+++ D D FL+ P+T H +DE SP
Sbjct: 205 KSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSP 264
Query: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVL-FEEKNQY 338
L + + E DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P + +Y
Sbjct: 265 LKDLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKY 323
Query: 339 KIDYSHFHKTYEVPS 353
D+S F + +V S
Sbjct: 324 IADFSLFDQVVKVAS 338
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 187 bits (475), Expect = 2e-47
Identities = 119/322 (36%), Positives = 178/322 (55%), Gaps = 17/322 (5%)
Query: 45 RFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
R V K+G + ++ YL D + +D+RWR+M+L+FS +F+ WL+F V+++V
Sbjct: 19 RMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
Query: 105 IAVAHGDLE-----PAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
+A +GDLE P E H T CV + F AAF FS+ETQ TIGYG + +C A+
Sbjct: 78 LAEMNGDLELDHDAPPENH--TICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
++ Q ++G ++++F+ GA +AK+ARPK RA ++ F+ AVVA DGK L+++V N R
Sbjct: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFD--KGLDRIFLVSPITILHEIDEA 277
S + V A L + R E G+ L Q +D D + F + P+T H I +
Sbjct: 196 PSPLTSVRVSAVLYQER--ENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-EKN 336
SPL + + + FE+VV L M E T Q R+SYL +EI+ H F +L K
Sbjct: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
Query: 337 QYKIDYSHFHKTYEVPSTPRCS 358
+Y+I +F KT TP S
Sbjct: 310 EYQIKMENFDKTVPEFPTPLVS 331
>gi|7706363 map kinase phosphatase-like protein MK-STYX [Homo
sapiens]
Length = 313
Score = 32.0 bits (71), Expect = 1.1
Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 22/95 (23%)
Query: 331 LFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANS-----FC--YENE--- 380
L + +++++ D SH V + R K+ N++LLP + +C Y+N
Sbjct: 33 LLDVRSKWEYDESH------VITALRVKKKN---NEYLLPESVDLECVKYCVVYDNNSST 83
Query: 381 LAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRL 415
L L +D++D++D D DG+ L PQA ++ R+
Sbjct: 84 LEILLKDDDDDSDSDGDGKD---LVPQAAIEYGRI 115
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,067,033
Number of Sequences: 37866
Number of extensions: 694029
Number of successful extensions: 2114
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2031
Number of HSP's gapped (non-prelim): 35
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.