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Search of human proteins with 239757991
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
(534 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 1093 0.0
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 875 0.0
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 875 0.0
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 833 0.0
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 818 0.0
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 593 e-169
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 524 e-149
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 524 e-149
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 463 e-130
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 463 e-130
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 379 e-105
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 371 e-103
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 366 e-101
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 354 1e-97
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 328 1e-89
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 320 3e-87
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 319 3e-87
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 319 3e-87
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 319 3e-87
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 319 3e-87
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 319 3e-87
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 303 2e-82
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 303 2e-82
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 303 2e-82
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 272 5e-73
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 272 5e-73
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 272 5e-73
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 270 2e-72
gi|239751251 PREDICTED: hypothetical protein [Homo sapiens] 186 6e-47
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 178 1e-44
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 1093 bits (2827), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 1 MTRWKSLKAPGPHKSSPCQLVASRQCLSAPALAASFWRVQESGAEPPSQHSLRGAPCLRL 60
MTRWKSLKAPGPHKSSPCQLVASRQCLSAPALAASFWRVQESGAEPPSQHSLRGAPCLRL
Sbjct: 1 MTRWKSLKAPGPHKSSPCQLVASRQCLSAPALAASFWRVQESGAEPPSQHSLRGAPCLRL 60
Query: 61 PTSWPRQKQCPPFQPCVPAPQRHGAALPGASLGESQGPPTPGMTAASRANPYSIVSSEED 120
PTSWPRQKQCPPFQPCVPAPQRHGAALPGASLGESQGPPTPGMTAASRANPYSIVSSEED
Sbjct: 61 PTSWPRQKQCPPFQPCVPAPQRHGAALPGASLGESQGPPTPGMTAASRANPYSIVSSEED 120
Query: 121 GLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDI 180
GLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDI
Sbjct: 121 GLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDI 180
Query: 181 RWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSI 240
RWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSI
Sbjct: 181 RWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSI 240
Query: 241 KTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSH 300
KTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSH
Sbjct: 241 KTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSH 300
Query: 301 NAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKG 360
NAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKG
Sbjct: 301 NAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKG 360
Query: 361 LDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLA 420
LDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLA
Sbjct: 361 LDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLA 420
Query: 421 NEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKN 480
NEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKN
Sbjct: 421 NEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKN 480
Query: 481 ELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI 534
ELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI
Sbjct: 481 ELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI 534
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 875 bits (2260), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 103 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 162
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM
Sbjct: 1 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 60
Query: 163 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 222
DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR
Sbjct: 61 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 120
Query: 223 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 282
TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 180
Query: 283 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 342
MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE
Sbjct: 181 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 240
Query: 343 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 402
GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 300
Query: 403 GIVEATAMTTQARSSYLANEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKD 462
GIVEATAMTTQARSSYLANEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKD
Sbjct: 301 GIVEATAMTTQARSSYLANEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKD 360
Query: 463 LVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGV 522
LVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGV
Sbjct: 361 LVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGV 420
Query: 523 LEQRPYRRESEI 534
LEQRPYRRESEI
Sbjct: 421 LEQRPYRRESEI 432
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 875 bits (2260), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 103 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 162
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM
Sbjct: 1 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 60
Query: 163 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 222
DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR
Sbjct: 61 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 120
Query: 223 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 282
TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 180
Query: 283 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 342
MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE
Sbjct: 181 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 240
Query: 343 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 402
GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 300
Query: 403 GIVEATAMTTQARSSYLANEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKD 462
GIVEATAMTTQARSSYLANEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKD
Sbjct: 301 GIVEATAMTTQARSSYLANEILWGHRFEPVLFEKNQYKIDYLHFHKTYEVPSTPRCSAKD 360
Query: 463 LVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGV 522
LVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGV
Sbjct: 361 LVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGV 420
Query: 523 LEQRPYRRESEI 534
LEQRPYRRESEI
Sbjct: 421 LEQRPYRRESEI 432
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 833 bits (2151), Expect = 0.0
Identities = 411/433 (94%), Positives = 421/433 (97%), Gaps = 1/433 (0%)
Query: 103 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 162
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNIEFANM
Sbjct: 1 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
Query: 163 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 222
DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFG+IFWVIAVAHGDLEPAEGRGR
Sbjct: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
Query: 223 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 282
TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEECPVAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
Query: 283 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 342
MAKM RPKKRAQTLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
Query: 343 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 402
GEYIPLDQIDIDVGFDKGLD FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
Query: 403 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 461
G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
Query: 462 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 521
DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
Query: 522 VLEQRPYRRESEI 534
VLEQRPYRRESEI
Sbjct: 421 VLEQRPYRRESEI 433
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 818 bits (2113), Expect = 0.0
Identities = 406/433 (93%), Positives = 415/433 (95%), Gaps = 1/433 (0%)
Query: 103 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 162
MTAASRANPYSIVS EEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNI FANM
Sbjct: 1 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60
Query: 163 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 222
DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEG GR
Sbjct: 61 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120
Query: 223 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 282
TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEEC VAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180
Query: 283 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 342
MAKM RPKKRA TLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
Query: 343 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 402
GEYIPLDQIDIDVGFDKGLD FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
Query: 403 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 461
G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
Query: 462 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 521
DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
Query: 522 VLEQRPYRRESEI 534
VLEQRPYRR SEI
Sbjct: 421 VLEQRPYRRGSEI 433
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 593 bits (1528), Expect = e-169
Identities = 291/431 (67%), Positives = 350/431 (81%), Gaps = 12/431 (2%)
Query: 108 RANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCHNRFVKKNGQCNIEFANMDEK 165
R N YSIVSSEEDG+ L TM+ ANGFGNGK VHTR++C +RFVKK+G CN++F N+ EK
Sbjct: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
Query: 166 SQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPA-EGRGRTP 224
QRYLADIFTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ + EG+
Sbjct: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKA--- 121
Query: 225 CVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMA 284
CV +V+ F AAFLFSI+TQ TI YG RCVT+ECP+AVFMVV QSIVGCII++F+IGA+MA
Sbjct: 122 CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMA 181
Query: 285 KMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGE 344
KM +PKKR +TL+FSHNAV+A+RDGKLC MWRVGNLRKSH+VEAHVRAQL+K R+T EGE
Sbjct: 182 KMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGE 241
Query: 345 YIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGI 404
YIPLDQIDI+VGFD G+D FLVSPITI+HEIDE SPL+ +S+QD+ DFEIV+ILEG+
Sbjct: 242 YIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGM 301
Query: 405 VEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDL 463
VEATAMTTQ RSSYLANEILWGHR+EPVLF EK+ YK+DY FHKTYEVP+TP CSA+DL
Sbjct: 302 VEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDL 361
Query: 464 VENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVL 523
E K++L ANSFCY+NE+A S++E+D +G + S + D D L
Sbjct: 362 AEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPL 416
Query: 524 EQRPYRRESEI 534
E RP RRESEI
Sbjct: 417 EPRPLRRESEI 427
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 524 bits (1350), Expect = e-149
Identities = 272/440 (61%), Positives = 330/440 (75%), Gaps = 41/440 (9%)
Query: 135 NGKVHT-RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAF 193
NG+ H RR+ NRFVKKNGQCN+ FAN+ KSQRY+ADIFTTCVD RWRYML+IFS AF
Sbjct: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
Query: 194 LASWLLFGVIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 237
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
Query: 238 FSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLL 297
FS++TQ TI YG RCVTEECP+AV VV QSIVGC+I+SFMIG IMAKM RPKKRAQTLL
Sbjct: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
Query: 298 FSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGF 357
FSH+AV+++RDGKLC MWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
Query: 358 DKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSS 417
D GLD FLVSPI I+HEIDE SPL+G+ +++L+ +DFEIV+ILEG+VEATAMTTQARSS
Sbjct: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
Query: 418 YLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL-----P 471
YLA+EILWGHRFEPV+F EK+ YK+DY FHKTYEV TP CSA++L E+K + P
Sbjct: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
Query: 472 RANSFCYKNELAFLSRDEEDEAD------------GDQDGRSRE-GLIPQ----ARHDFD 514
++FCY+NELA +S++EE+ + G + G E G+I + D +
Sbjct: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426
Query: 515 RLQAGGGVLEQRPYRRESEI 534
R+QA L+ YRRES I
Sbjct: 427 RMQA-SLPLDNISYRRESAI 445
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 524 bits (1350), Expect = e-149
Identities = 272/440 (61%), Positives = 330/440 (75%), Gaps = 41/440 (9%)
Query: 135 NGKVHT-RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAF 193
NG+ H RR+ NRFVKKNGQCN+ FAN+ KSQRY+ADIFTTCVD RWRYML+IFS AF
Sbjct: 7 NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66
Query: 194 LASWLLFGVIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 237
L SWL FG++FW IA HGDLE PA G G PC+M V+GF+ AFL
Sbjct: 67 LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126
Query: 238 FSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLL 297
FS++TQ TI YG RCVTEECP+AV VV QSIVGC+I+SFMIG IMAKM RPKKRAQTLL
Sbjct: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186
Query: 298 FSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGF 357
FSH+AV+++RDGKLC MWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246
Query: 358 DKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSS 417
D GLD FLVSPI I+HEIDE SPL+G+ +++L+ +DFEIV+ILEG+VEATAMTTQARSS
Sbjct: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306
Query: 418 YLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL-----P 471
YLA+EILWGHRFEPV+F EK+ YK+DY FHKTYEV TP CSA++L E+K + P
Sbjct: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366
Query: 472 RANSFCYKNELAFLSRDEEDEAD------------GDQDGRSRE-GLIPQ----ARHDFD 514
++FCY+NELA +S++EE+ + G + G E G+I + D +
Sbjct: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426
Query: 515 RLQAGGGVLEQRPYRRESEI 534
R+QA L+ YRRES I
Sbjct: 427 RMQA-SLPLDNISYRRESAI 445
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 463 bits (1191), Expect = e-130
Identities = 232/386 (60%), Positives = 288/386 (74%), Gaps = 17/386 (4%)
Query: 131 NGFGNGKVHT---RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLL 187
NG+ V + RRR RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L
Sbjct: 34 NGWAPAPVQSPVGRRR--GRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCL 91
Query: 188 IFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTIS 247
+FS +FLASWLLFG+ FW+IA HGDL A PC V F+AAFLF+++TQ +I
Sbjct: 92 LFSCSFLASWLLFGLAFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIG 149
Query: 248 YGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALR 307
YG+R VTEECP AV VV Q I GC++++F++GA+MAKM +PKKR +TL+FS NAVVALR
Sbjct: 150 YGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALR 209
Query: 308 DGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLV 367
D +LC MWRVGNLR+SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G D FLV
Sbjct: 210 DHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLV 269
Query: 368 SPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGH 427
SPITI+HEID ASPL+ + R +L DFE+V+ILEG+VEATAMTTQ RSSYL E+LWGH
Sbjct: 270 SPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGH 329
Query: 428 RFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRCSAKDLVEN--------KFLLPRA-NSFC 477
RFEPVLF++ +QY++DY HFH+TYEVP TP CSAK+L E K P + +FC
Sbjct: 330 RFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFC 389
Query: 478 YKNELAFLSRDEEDEADGDQDGRSRE 503
Y+NELA EEDE D ++G E
Sbjct: 390 YENELALSCCQEEDEDDETEEGNGVE 415
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 463 bits (1191), Expect = e-130
Identities = 232/386 (60%), Positives = 288/386 (74%), Gaps = 17/386 (4%)
Query: 131 NGFGNGKVHT---RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLL 187
NG+ V + RRR RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L
Sbjct: 34 NGWAPAPVQSPVGRRR--GRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCL 91
Query: 188 IFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTIS 247
+FS +FLASWLLFG+ FW+IA HGDL A PC V F+AAFLF+++TQ +I
Sbjct: 92 LFSCSFLASWLLFGLAFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIG 149
Query: 248 YGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALR 307
YG+R VTEECP AV VV Q I GC++++F++GA+MAKM +PKKR +TL+FS NAVVALR
Sbjct: 150 YGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALR 209
Query: 308 DGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLV 367
D +LC MWRVGNLR+SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G D FLV
Sbjct: 210 DHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLV 269
Query: 368 SPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGH 427
SPITI+HEID ASPL+ + R +L DFE+V+ILEG+VEATAMTTQ RSSYL E+LWGH
Sbjct: 270 SPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGH 329
Query: 428 RFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRCSAKDLVEN--------KFLLPRA-NSFC 477
RFEPVLF++ +QY++DY HFH+TYEVP TP CSAK+L E K P + +FC
Sbjct: 330 RFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFC 389
Query: 478 YKNELAFLSRDEEDEADGDQDGRSRE 503
Y+NELA EEDE D ++G E
Sbjct: 390 YENELALSCCQEEDEDDETEEGNGVE 415
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 379 bits (973), Expect = e-105
Identities = 191/360 (53%), Positives = 258/360 (71%), Gaps = 6/360 (1%)
Query: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
RRR R+V+K+G+CN++ N+ E + RYL D+FTT VD++WR LL F LA+ +WL F
Sbjct: 17 RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
Query: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260
G I+W+IA GDLE E TPCV ++GF+AAFLFSI+T+ TI YG R +T++CP
Sbjct: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
Query: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320
+ +++ Q+I+G ++N+FM+G + K+ +P KRA TL+FS +AVV+LRDG+LC M+RVG+L
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
Query: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380
R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G D FLVSP+ I HEID AS
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
Query: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439
P + SR+ L+ DDFEIV+ILEG+VEAT MT QARSSYL +E+LWGHRF VL E Y
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
Query: 440 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDG 499
++DY FH+T+EVP TP CSA++L E R ++ Y + + L E+E G+ G
Sbjct: 316 EVDYASFHETFEVP-TPSCSARELAE---AAARLDAHLYWSIPSRLDEKVEEEGAGEGAG 371
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 371 bits (953), Expect = e-103
Identities = 185/375 (49%), Positives = 262/375 (69%), Gaps = 12/375 (3%)
Query: 142 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 201
++ R+++K+G+CN+ N+ E + RYL+D+FTT VD++WR+ LL+F++ + +WL FG
Sbjct: 47 KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
Query: 202 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
I+W+IA GDL+ + PCV + GF++AFLFSI+T+ TI YG R +TE+CP +
Sbjct: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165
Query: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
+++ Q+I+G I+N+FM+G + K+ +PKKRA+TL+FS+NAV+++RD KLC M+RVG+LR
Sbjct: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225
Query: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 381
SHIVEA +RA+LIK R TKEGE+IPL+Q DI+VGFD G D FLVSP+ I HEI++ SP
Sbjct: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285
Query: 382 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 440
+ +S+ L ++FE+V+ILEG+VEAT MT QARSSY+ E+LWGHRF PVL EK Y+
Sbjct: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345
Query: 441 IDYLHFHKTYEVPSTPRCSAKDLVENK--------FLLPRANSFCYKNEL-AFLSRDEED 491
+DY FH TYE +TP C AK+L E K P C + L A ++EED
Sbjct: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404
Query: 492 EADGDQDGRSREGLI 506
E G R G +
Sbjct: 405 EPKGLGGSREARGSV 419
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 366 bits (940), Expect = e-101
Identities = 185/364 (50%), Positives = 265/364 (72%), Gaps = 6/364 (1%)
Query: 142 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 201
+R R+V+K+G+CN+ N+ E + RYL DIFTT VD++WR+ LLIF + + +WL FG
Sbjct: 50 KRKIQRYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
Query: 202 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
+I+W+IA GD++ E TPCV ++GF++AFLFSI+T+ TI YG R +T++CP +
Sbjct: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168
Query: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
+++ QS++G I+N+FM+G + K+ +PKKRA+TL+FS +AV+++RDGKLC M+RVG+LR
Sbjct: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228
Query: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 381
SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G D FLVSP+ I HEI++ SP
Sbjct: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288
Query: 382 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 440
+ IS+ L ++ EIV+ILEG+VEAT MT QARSSY+ +EILWG+RF PVL E Y+
Sbjct: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348
Query: 441 IDYLHFHKTYEVPSTPRCSAKDLVE--NKFLLPRANSFCYK-NELAFLSRDEEDEADGDQ 497
+DY FH+TYE STP SAK+L E ++ LP + S K N+ A L +EE++ +Q
Sbjct: 349 VDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQ 407
Query: 498 DGRS 501
R+
Sbjct: 408 TERN 411
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 354 bits (909), Expect = 1e-97
Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%)
Query: 112 YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 171
Y +V++ G L V ++R RFV KNG+CN++ N+ ++ RYL+
Sbjct: 12 YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69
Query: 172 DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 231
D+FTT VD++WR+ L IF L + +WL ++WVIA GDL A TPCV V+
Sbjct: 70 DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129
Query: 232 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 291
F +AFLF I+T+ TI YG R +T++CP + + + QSI+G I+++F+IG + KM +PKK
Sbjct: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189
Query: 292 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 351
RA+TL+FS +AV+++RDGKL M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+
Sbjct: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249
Query: 352 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 411
++DVGF G D FLVSP+TI H ID SP + +S++ +Q + FEIV+ILEGIVE T MT
Sbjct: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309
Query: 412 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 465
QAR+SY +E+LWGHRF PV+ E+ +K+DY FH T+EVP TP S K+ E
Sbjct: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 328 bits (840), Expect = 1e-89
Identities = 165/331 (49%), Positives = 233/331 (70%), Gaps = 5/331 (1%)
Query: 142 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 201
R+ RFV K G CN+ N+ E+ R+L D+FTT VD++W + LLIF+++FL SWLLF
Sbjct: 29 RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
Query: 202 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
+ +W+IA AHGDL P+EG PCV +H F +AFLFSI+ Q TI +G R VTEECP+A+
Sbjct: 88 MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146
Query: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
+++ Q+IVG +IN+ M+G I K + +RA+TL+FS +AV+ALR G+LCFM RVG+LR
Sbjct: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206
Query: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 381
KS I+ A + Q+++ + EGE +PL Q+DI + G + FLV+P+ I H ID SP
Sbjct: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266
Query: 382 LFGISRQDL-QMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLFEKN-QY 439
L+ ++ DL D EI++ILEG+VE T +TTQAR+SYLA+EILWG RF P++ E++ +Y
Sbjct: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326
Query: 440 KIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 470
+DY F T +VP TP C+A+ L E+ LL
Sbjct: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 320 bits (819), Expect = 3e-87
Identities = 161/333 (48%), Positives = 230/333 (69%), Gaps = 11/333 (3%)
Query: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206
RF+ K+G CN+ N+ E+ R+L DIFTT VD++WR+ L+IF+++FL SWLLF +++W+
Sbjct: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
Query: 207 IAVAHGDLEP--------AEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECP 258
+A AHGD+ G T CV V F +AFLFSI+ Q TI +G R +TEECP
Sbjct: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
Query: 259 VAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVG 318
+A+ +++ Q+IVG IIN+ M+G I K + +RA+TL+FS +AV+A+R+GKLCFM+RVG
Sbjct: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
Query: 319 NLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDE 378
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V ++ FLV+P+ I H ID+
Sbjct: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
Query: 379 ASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKN 437
SPL+ IS DL D E+++ILEG+VE T +TTQAR+SY+A EI WGHRF ++ E+
Sbjct: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
Query: 438 QYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 470
Y +DY F T +V + PRCSA++L E +L
Sbjct: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 319 bits (818), Expect = 3e-87
Identities = 158/325 (48%), Positives = 229/325 (70%), Gaps = 7/325 (2%)
Query: 139 HTRRRCHNRFVKKNGQCNIEFANMDEKSQR-YLADIFTTCVDIRWRYMLLIFSLAFLASW 197
H+R+R R V K+G+CNIEF N++ +S+ + DI+TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRA--RLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 198 LLFGVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEE 256
FG++++ +A H DL E TPCV ++G +AFLFS++TQ TI YG RCVTE+
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 257 CPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWR 316
C A+F+++ QSI+G IINSFM GAI+AK+ RPKKRA+T+ FS NAV++ R GKLC + R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 317 VGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEI 376
V NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G ++ F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 377 DEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL--F 434
D SP F ++ + L DFE+V+ L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 435 EKNQYKIDYLHFHKTYEVPSTPRCS 459
++ +Y++D+ +F KT EV TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 319 bits (818), Expect = 3e-87
Identities = 158/325 (48%), Positives = 229/325 (70%), Gaps = 7/325 (2%)
Query: 139 HTRRRCHNRFVKKNGQCNIEFANMDEKSQR-YLADIFTTCVDIRWRYMLLIFSLAFLASW 197
H+R+R R V K+G+CNIEF N++ +S+ + DI+TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRA--RLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 198 LLFGVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEE 256
FG++++ +A H DL E TPCV ++G +AFLFS++TQ TI YG RCVTE+
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 257 CPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWR 316
C A+F+++ QSI+G IINSFM GAI+AK+ RPKKRA+T+ FS NAV++ R GKLC + R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 317 VGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEI 376
V NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G ++ F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 377 DEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL--F 434
D SP F ++ + L DFE+V+ L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 435 EKNQYKIDYLHFHKTYEVPSTPRCS 459
++ +Y++D+ +F KT EV TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 319 bits (818), Expect = 3e-87
Identities = 158/325 (48%), Positives = 229/325 (70%), Gaps = 7/325 (2%)
Query: 139 HTRRRCHNRFVKKNGQCNIEFANMDEKSQR-YLADIFTTCVDIRWRYMLLIFSLAFLASW 197
H+R+R R V K+G+CNIEF N++ +S+ + DI+TT +D++WRY + IF AFL SW
Sbjct: 35 HSRQRA--RLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 92
Query: 198 LLFGVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEE 256
FG++++ +A H DL E TPCV ++G +AFLFS++TQ TI YG RCVTE+
Sbjct: 93 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 152
Query: 257 CPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWR 316
C A+F+++ QSI+G IINSFM GAI+AK+ RPKKRA+T+ FS NAV++ R GKLC + R
Sbjct: 153 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 212
Query: 317 VGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEI 376
V NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G ++ F +SP+TI H I
Sbjct: 213 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 272
Query: 377 DEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL--F 434
D SP F ++ + L DFE+V+ L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 273 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 332
Query: 435 EKNQYKIDYLHFHKTYEVPSTPRCS 459
++ +Y++D+ +F KT EV TP C+
Sbjct: 333 KEGKYRVDFHNFSKTVEV-ETPHCA 356
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 319 bits (818), Expect = 3e-87
Identities = 158/325 (48%), Positives = 229/325 (70%), Gaps = 7/325 (2%)
Query: 139 HTRRRCHNRFVKKNGQCNIEFANMDEKSQR-YLADIFTTCVDIRWRYMLLIFSLAFLASW 197
H+R+R R V K+G+CNIEF N++ +S+ + DI+TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRA--RLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 198 LLFGVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEE 256
FG++++ +A H DL E TPCV ++G +AFLFS++TQ TI YG RCVTE+
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 257 CPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWR 316
C A+F+++ QSI+G IINSFM GAI+AK+ RPKKRA+T+ FS NAV++ R GKLC + R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 317 VGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEI 376
V NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G ++ F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 377 DEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL--F 434
D SP F ++ + L DFE+V+ L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 435 EKNQYKIDYLHFHKTYEVPSTPRCS 459
++ +Y++D+ +F KT EV TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 319 bits (818), Expect = 3e-87
Identities = 158/325 (48%), Positives = 229/325 (70%), Gaps = 7/325 (2%)
Query: 139 HTRRRCHNRFVKKNGQCNIEFANMDEKSQR-YLADIFTTCVDIRWRYMLLIFSLAFLASW 197
H+R+R R V K+G+CNIEF N++ +S+ + DI+TT +D++WRY + IF AFL SW
Sbjct: 16 HSRQRA--RLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 198 LLFGVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEE 256
FG++++ +A H DL E TPCV ++G +AFLFS++TQ TI YG RCVTE+
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 257 CPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWR 316
C A+F+++ QSI+G IINSFM GAI+AK+ RPKKRA+T+ FS NAV++ R GKLC + R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 317 VGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEI 376
V NLRKS ++ +H+ +L+K VT EGE I LDQI+I+ D G ++ F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 377 DEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL--F 434
D SP F ++ + L DFE+V+ L+G VE+T+ T Q R+SY+ E+LWG+RF P++
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 435 EKNQYKIDYLHFHKTYEVPSTPRCS 459
++ +Y++D+ +F KT EV TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 303 bits (777), Expect = 2e-82
Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%)
Query: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
+RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260
G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320
V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380
R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S
Sbjct: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261
Query: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439
PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y
Sbjct: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
Query: 440 KIDYLHFHKTYEVPSTPRCSAKDL 463
K++ L F + EV P CSAK L
Sbjct: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 303 bits (777), Expect = 2e-82
Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%)
Query: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
+RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260
G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320
V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380
R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S
Sbjct: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261
Query: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439
PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y
Sbjct: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
Query: 440 KIDYLHFHKTYEVPSTPRCSAKDL 463
K++ L F + EV P CSAK L
Sbjct: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 303 bits (777), Expect = 2e-82
Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%)
Query: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
+RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260
G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA
Sbjct: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
Query: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320
V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
Query: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380
R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S
Sbjct: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261
Query: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439
PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y
Sbjct: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
Query: 440 KIDYLHFHKTYEVPSTPRCSAKDL 463
K++ L F + EV P CSAK L
Sbjct: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 272 bits (696), Expect = 5e-73
Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)
Query: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206
R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++
Sbjct: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
Query: 207 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 265
IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
Query: 266 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 325
AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS +
Sbjct: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
Query: 326 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 385
++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL +
Sbjct: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
Query: 386 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 443
+ Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+
Sbjct: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
Query: 444 LHFHKTYEVPSTPRC------SAKDLVENKF 468
F ++ +P C S K +E K+
Sbjct: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 272 bits (696), Expect = 5e-73
Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)
Query: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206
R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++
Sbjct: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
Query: 207 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 265
IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
Query: 266 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 325
AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS +
Sbjct: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
Query: 326 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 385
++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL +
Sbjct: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
Query: 386 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 443
+ Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+
Sbjct: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
Query: 444 LHFHKTYEVPSTPRC------SAKDLVENKF 468
F ++ +P C S K +E K+
Sbjct: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 272 bits (696), Expect = 5e-73
Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)
Query: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206
R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++
Sbjct: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
Query: 207 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 265
IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
Query: 266 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 325
AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS +
Sbjct: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
Query: 326 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 385
++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL +
Sbjct: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
Query: 386 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 443
+ Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+
Sbjct: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
Query: 444 LHFHKTYEVPSTPRC------SAKDLVENKF 468
F ++ +P C S K +E K+
Sbjct: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 270 bits (691), Expect = 2e-72
Identities = 139/317 (43%), Positives = 205/317 (64%), Gaps = 7/317 (2%)
Query: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
RRR R + K+G+ N+ ++ +K YL D++TT +D++WRY LL+FS F +W LF
Sbjct: 26 RRR---RVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82
Query: 201 GVIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPV 259
GV+++++AVAHGDL E TPCV+QVH AFLFS+++Q TI YG R ++EECP+
Sbjct: 83 GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
Query: 260 AVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGN 319
A+ +++AQ ++ I+ F+ G +AK+ RPKKRA+T+ FS +AVVA +GK C M RV N
Sbjct: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
Query: 320 LRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEA 379
+RKS ++ V +L++ TKEGE I L+Q+++ D D FL+ P+T H +DE
Sbjct: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262
Query: 380 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKN 437
SPL + + + DFE+V+IL G VE+T+ T Q R+SYL EILWG+ F P L
Sbjct: 263 SPLKDLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321
Query: 438 QYKIDYLHFHKTYEVPS 454
+Y D+ F + +V S
Sbjct: 322 KYIADFSLFDQVVKVAS 338
>gi|239751251 PREDICTED: hypothetical protein [Homo sapiens]
Length = 201
Score = 186 bits (471), Expect = 6e-47
Identities = 84/93 (90%), Positives = 87/93 (93%)
Query: 1 MTRWKSLKAPGPHKSSPCQLVASRQCLSAPALAASFWRVQESGAEPPSQHSLRGAPCLRL 60
MTRWKSLKAPGPHKSSPCQLVASRQCLSAPALAASFWRVQESGAEPPSQHSLRGAPC RL
Sbjct: 77 MTRWKSLKAPGPHKSSPCQLVASRQCLSAPALAASFWRVQESGAEPPSQHSLRGAPCRRL 136
Query: 61 PTSWPRQKQCPPFQPCVPAPQRHGAALPGASLG 93
PTSWPRQKQCPPFQPCVPAPQRHG + + +G
Sbjct: 137 PTSWPRQKQCPPFQPCVPAPQRHGEVVSRSGVG 169
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 178 bits (451), Expect = 1e-44
Identities = 111/322 (34%), Positives = 173/322 (53%), Gaps = 14/322 (4%)
Query: 145 HNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 204
+ R V K+G ++ ++ YL D + +D+RWR+M+L+FS +F+ WL+F V++
Sbjct: 17 YRRMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
Query: 205 WVIAVAHGDLE---PAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
+V+A +GDLE A T CV + F AAF FS++TQ TI YG + +CP A+
Sbjct: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
Query: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
++ Q ++G ++ +F+ GA +AK+ RPK RA ++ F+ AVVA DGK +++V N R
Sbjct: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
Query: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFD--KGLDHSFLVSPITILHEIDEA 379
S + V A L + R E L Q +D D + F + P+T H I +
Sbjct: 196 PSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
Query: 380 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF--EKN 437
SPL + + + FE+V+ L + E T Q R+SYL +EI+ H F +L K
Sbjct: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
Query: 438 QYKIDYLHFHKTYEVPSTPRCS 459
+Y+I +F KT TP S
Sbjct: 310 EYQIKMENFDKTVPEFPTPLVS 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,982,076
Number of Sequences: 37866
Number of extensions: 1075953
Number of successful extensions: 3907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 3773
Number of HSP's gapped (non-prelim): 133
length of query: 534
length of database: 18,247,518
effective HSP length: 107
effective length of query: 427
effective length of database: 14,195,856
effective search space: 6061630512
effective search space used: 6061630512
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.