Guide to the Human Genome
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Search of human proteins with 239755176

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755176 PREDICTED: similar to solute carrier family 25,
member 25 isoform 2 [Homo sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755176 PREDICTED: similar to solute carrier family 25, mem...   937   0.0  
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ...   937   0.0  
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ...   832   0.0  
gi|239755174 PREDICTED: similar to solute carrier family 25, mem...   832   0.0  
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ...   832   0.0  
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ...   731   0.0  
gi|48476342 solute carrier family 25, member 23 [Homo sapiens]        605   e-173
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ...   585   e-167
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s...   584   e-167
gi|149274607 solute carrier family 25, member 41 [Homo sapiens]       324   1e-88
gi|60460887 solute carrier family 25, member 42 [Homo sapiens]        176   4e-44
gi|27544933 solute carrier family 25, member 16 [Homo sapiens]        171   1e-42
gi|21687151 mitochondrial solute carrier protein [Homo sapiens]       125   1e-28
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade...   116   5e-26
gi|156071459 solute carrier family 25, member 5 [Homo sapiens]        115   7e-26
gi|156071462 solute carrier family 25, member A6 [Homo sapiens]       115   1e-25
gi|186928856 solute carrier family 25, member 19 [Homo sapiens]       115   1e-25
gi|186928860 solute carrier family 25, member 19 [Homo sapiens]       115   1e-25
gi|186928858 solute carrier family 25, member 19 [Homo sapiens]       115   1e-25
gi|21314739 solute carrier family 25, member 32 [Homo sapiens]        113   3e-25
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade...   113   4e-25
gi|157388989 solute carrier family 25, member 36 isoform a [Homo...   108   8e-24
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho...   106   5e-23
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H...   106   5e-23
gi|157388991 solute carrier family 25, member 36 isoform b [Homo...   105   1e-22
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]      102   1e-21
gi|58197562 solute carrier family 25, member 30 [Homo sapiens]        100   5e-21
gi|82775373 solute carrier family 25, member 37 [Homo sapiens]         93   5e-19
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ...    93   6e-19
gi|149274643 solute carrier family 25, member 28 [Homo sapiens]        92   1e-18

>gi|239755176 PREDICTED: similar to solute carrier family 25, member
           25 isoform 2 [Homo sapiens]
          Length = 469

 Score =  937 bits (2423), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60
           MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD
Sbjct: 1   MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60

Query: 61  KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120
           KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE
Sbjct: 61  KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120

Query: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180
           KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE
Sbjct: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180

Query: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
           RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR
Sbjct: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240

Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
           SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300

Query: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
           MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360

Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420
           KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS
Sbjct: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420

Query: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469


>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
           sapiens]
          Length = 469

 Score =  937 bits (2423), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60
           MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD
Sbjct: 1   MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60

Query: 61  KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120
           KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE
Sbjct: 61  KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120

Query: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180
           KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE
Sbjct: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180

Query: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
           RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR
Sbjct: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240

Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
           SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300

Query: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
           MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360

Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420
           KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS
Sbjct: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420

Query: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469


>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
           sapiens]
          Length = 489

 Score =  832 bits (2150), Expect = 0.0
 Identities = 417/420 (99%), Positives = 419/420 (99%)

Query: 50  QWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRD 109
           Q+ +KIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRD
Sbjct: 70  QFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRD 129

Query: 110 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGEN 169
           LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGEN
Sbjct: 130 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGEN 189

Query: 170 LTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGG 229
           LTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGG
Sbjct: 190 LTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGG 249

Query: 230 FTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL 289
           FTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL
Sbjct: 250 FTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL 309

Query: 290 AGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPY 349
           AGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPY
Sbjct: 310 AGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPY 369

Query: 350 AGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA 409
           AGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA
Sbjct: 370 AGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA 429

Query: 410 SIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           SIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 430 SIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 489


>gi|239755174 PREDICTED: similar to solute carrier family 25, member
           25 isoform 1 [Homo sapiens]
          Length = 503

 Score =  832 bits (2149), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 53  QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
           QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 87  QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146

Query: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
           KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206

Query: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
           PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266

Query: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
           MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326

Query: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
           IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386

Query: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
           DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446

Query: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 20/65 (30%), Positives = 38/65 (58%)

Query: 78  DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 137
           DH  +L  +F++LD   DG +   ++   LR LG+  +E + +KI+++ DK+    +D+ 
Sbjct: 45  DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104

Query: 138 EWRDY 142
           E+  Y
Sbjct: 105 EFVHY 109


>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
           sapiens]
          Length = 503

 Score =  832 bits (2149), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 53  QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
           QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 87  QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146

Query: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
           KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206

Query: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
           PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266

Query: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
           MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326

Query: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
           IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386

Query: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
           DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446

Query: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 20/65 (30%), Positives = 38/65 (58%)

Query: 78  DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 137
           DH  +L  +F++LD   DG +   ++   LR LG+  +E + +KI+++ DK+    +D+ 
Sbjct: 45  DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104

Query: 138 EWRDY 142
           E+  Y
Sbjct: 105 EFVHY 109


>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
           sapiens]
          Length = 366

 Score =  731 bits (1886), Expect = 0.0
 Identities = 366/366 (100%), Positives = 366/366 (100%)

Query: 104 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 163
           MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI
Sbjct: 1   MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 60

Query: 164 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 223
           FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN
Sbjct: 61  FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 120

Query: 224 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 283
           MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER
Sbjct: 121 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 180

Query: 284 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 343
           LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM
Sbjct: 181 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 240

Query: 344 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 403
           LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT
Sbjct: 241 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 300

Query: 404 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 463
           RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT
Sbjct: 301 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 360

Query: 464 LGVQSR 469
           LGVQSR
Sbjct: 361 LGVQSR 366


>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
          Length = 468

 Score =  605 bits (1560), Expect = e-173
 Identities = 296/418 (70%), Positives = 344/418 (82%)

Query: 52  KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111
           +Q I   GD D DG LD EEF  YLQ+ E++L L+F SLD+  DG ID  EI QS R LG
Sbjct: 51  QQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALG 110

Query: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171
           + IS +QAEKIL SMD++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LT
Sbjct: 111 ISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLT 170

Query: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231
           VPDEF+ +E+ TGMWW+ LVAG  AGAVSRT TAPLDRLKV MQVHAS++N + I+GG  
Sbjct: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLR 230

Query: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291
            M+ EGG RSLWRGNGINVLKIAPESAIKFMAYEQIKR +   QETL + ER VAGSLAG
Sbjct: 231 SMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAG 290

Query: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
           A AQ+ IYPMEVLKTR+ LR+TGQY G+LDCARRIL REG  AFY+GY+PN+LGIIPYAG
Sbjct: 291 ATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350

Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
           IDLAVYETLKN WLQ Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASI
Sbjct: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410

Query: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           EG P+++M  L +HIL  EG  GLYRG+APNFMKVIPAVSISYVVYEN+K  LGV SR
Sbjct: 411 EGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468


>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
           sapiens]
          Length = 477

 Score =  585 bits (1507), Expect = e-167
 Identities = 276/418 (66%), Positives = 347/418 (83%)

Query: 52  KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111
           ++KI   GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG
Sbjct: 60  EEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLG 119

Query: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171
           + ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST  D+G++LT
Sbjct: 120 LTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLT 179

Query: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231
           +PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF 
Sbjct: 180 IPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR 239

Query: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291
           QM++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+  + + +   ER ++GS+AG
Sbjct: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299

Query: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
           A AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL  EG+ AFYKGYVPN+LGIIPYAG
Sbjct: 300 ATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359

Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
           IDLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +
Sbjct: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419

Query: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           EG+P++ M  LF+ I+  EG  GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV  +
Sbjct: 420 EGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477


>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
           sapiens]
          Length = 458

 Score =  584 bits (1505), Expect = e-167
 Identities = 276/417 (66%), Positives = 346/417 (82%)

Query: 53  QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
           +KI   GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+
Sbjct: 42  KKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 101

Query: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
            ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST  D+G++LT+
Sbjct: 102 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 161

Query: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
           PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Q
Sbjct: 162 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 221

Query: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
           M++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+  + + +   ER ++GS+AGA
Sbjct: 222 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 281

Query: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
            AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL  EG+ AFYKGYVPN+LGIIPYAGI
Sbjct: 282 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 341

Query: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
           DLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +E
Sbjct: 342 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 401

Query: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
           G+P++ M  LF+ I+  EG  GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV  +
Sbjct: 402 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458


>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
          Length = 370

 Score =  324 bits (830), Expect = 1e-88
 Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)

Query: 163 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 222
           + D GE L VP E    + +  +W + L++G  AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 70  VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128

Query: 223 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 282
              ++GG   M++EGG RSLWRGNGINVLKIAPE AIKF  +EQ K      Q +    E
Sbjct: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188

Query: 283 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 342
           RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG  A Y+GY+PN
Sbjct: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248

Query: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
           MLGIIPYA  DLAVYE L+  W++    +  DP   V L+  T+S+TCGQ+ASYPL LVR
Sbjct: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307

Query: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
           TRMQAQ ++EG+   TM  + + IL  +G  GLYRG+ P  +KV+PA  ISYVVYE +K 
Sbjct: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366

Query: 463 TLGV 466
           TLG+
Sbjct: 367 TLGI 370


>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
          Length = 318

 Score =  176 bits (446), Expect = 4e-44
 Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)

Query: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 249
           L+ G  AGA+++T  APLDR K++ QV + R +               G  SLWRGN   
Sbjct: 37  LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96

Query: 250 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
           ++++ P +AI+F A+E+ KR++GS      E L    RL AG+LAG  A S  YP+++++
Sbjct: 97  MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156

Query: 306 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
            RMA+     YS +     RI   EG+   Y G++P +LG+IPYAG+    YETLK+  L
Sbjct: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214

Query: 366 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 425
                    P  F  +  G  +   GQ ASYPL +VR RMQ  A + G P  +++   + 
Sbjct: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273

Query: 426 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
           I+R EGA  GLY+GL+ N++K   AV IS+  ++ ++I L
Sbjct: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)

Query: 271 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 327
           V S ++  ++   L+ G+LAGA+A++++ P++  +T++  + + +     +  R +    
Sbjct: 24  VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81

Query: 328 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 387
             EG  + ++G    M+ ++PYA I  + +E  K     +Y         +  L  G ++
Sbjct: 82  LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141

Query: 388 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 444
            T     +YPL LVR RM         P+   S++F     I R EG   LY G  P  +
Sbjct: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195

Query: 445 KVIPAVSISYVVYENLK 461
            VIP   +S+  YE LK
Sbjct: 196 GVIPYAGLSFFTYETLK 212



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 384 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 443
           G ++    + A  PL   +   Q  +    A E      + ++   EG   L+RG +   
Sbjct: 40  GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97

Query: 444 MKVIPAVSISYVVYENLKITLG 465
           ++V+P  +I +  +E  K  LG
Sbjct: 98  VRVVPYAAIQFSAHEEYKRILG 119


>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
          Length = 332

 Score =  171 bits (434), Expect = 1e-42
 Identities = 102/296 (34%), Positives = 164/296 (55%), Gaps = 15/296 (5%)

Query: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
           R+   W R  +AGG AG  ++T  APLDR+KVL+Q H     ++G+      + ++ G  
Sbjct: 31  RRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFL 90

Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
            L++GNG  +++I P  AI+FMA+E  K L+ +         RL+AGS+AG  A    YP
Sbjct: 91  GLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYP 150

Query: 301 MEVLKTRMALRKTGQ--YSGMLDCARRILARE-GVAAFYKGYVPNMLGIIPYAGIDLAVY 357
           +++++ R+A +  G+  Y+G++   + I A+E G   FY+G +P +LG+ PYAG+    +
Sbjct: 151 LDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTF 210

Query: 358 ETLKNAWLQHYAV-----NSADPGVFVL-----LACGTMSSTCGQLASYPLALVRTRMQA 407
            TLK+  L H        +S +P V VL     L CG ++    Q  SYP  + R RMQ 
Sbjct: 211 GTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQL 270

Query: 408 QASI-EGAPEVTMSSLFKHILRTEG-AFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
              + E    +TM    K++    G   GLYRGL+ N+++ IP+ ++++  YE +K
Sbjct: 271 GTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMK 326



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 14/90 (15%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHA---------SRSNNMGIVGGFTQMIREGGA 239
           +L+ GG AGA+++T + P D  +  MQ+           +  + M  V G       G  
Sbjct: 243 NLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYG-----HHGIR 297

Query: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKR 269
           + L+RG  +N ++  P  A+ F  YE +K+
Sbjct: 298 KGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327


>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
          Length = 341

 Score =  125 bits (313), Expect = 1e-28
 Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
           + L+  G AG +S + TAPL+   VL QV   R +  G      ++ R  G R+LW+GN 
Sbjct: 14  QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73

Query: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
           +  L++ P SA++  AY +   L   D   +     ++AGSLAG ++    YP +++KTR
Sbjct: 74  VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133

Query: 308 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
           + ++      Y G+L     I  +EG  A Y+G    ++G +P++   L VY  L+  W 
Sbjct: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192

Query: 366 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 419
                 +     F L    A   +++   Q  S+P   V+ +MQAQ+      G  +V  
Sbjct: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246

Query: 420 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           S     F+ I++ +G  GL+ GL  N +K++P   I +  +E  K
Sbjct: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)

Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 245
           W  ++AG  AG VS   T P D +K  L+  +    +  G++  F+ + ++ G  +L+RG
Sbjct: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166

Query: 246 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
             + V+   P SA   + Y  ++++    ++   + +      LA A+ Q+  +P E +K
Sbjct: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226

Query: 306 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 356
            +M      L  +G     +SG +DC R+I+  +GV   + G   N+L I+PY GI  + 
Sbjct: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286

Query: 357 YETLKNAWL 365
           +E  K   L
Sbjct: 287 FEFCKRICL 295


>gi|13775208 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 31 [Homo
           sapiens]
          Length = 315

 Score =  116 bits (290), Expect = 5e-26
 Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 241
           + L+AGG A AVS+T  AP++R+K+L+QV AS       +   G+V    ++ RE G  S
Sbjct: 22  KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81

Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 296
            WRGN  NV++  P  A+ F   ++ K+L    V  +++  R     L +G  AGA +  
Sbjct: 82  FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141

Query: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
            +YP++  +TR+ +      +  Q+ G+ DC  +I   +G+A  Y+G+  ++ GII Y  
Sbjct: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201

Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
                Y+T+K                 V      + +TC  + SYP   VR RM  Q+  
Sbjct: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256

Query: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
                      F  I + EG    +RG   N ++     ++  V+Y+ +K
Sbjct: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)

Query: 179 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 233
           +E+Q   W+   +A GG AGA S     PLD  +  + V   +        G+     ++
Sbjct: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176

Query: 234 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 293
            +  G   L++G G++V  I    A  F AY+ +K L+   ++T      LV+  +A  +
Sbjct: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232

Query: 294 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 344
              S    YP + ++ RM ++      QY G LDC  +I   EG+++F++G   N+L
Sbjct: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289


>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
          Length = 298

 Score =  115 bits (289), Expect = 7e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 241
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69

Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 296
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129

Query: 297 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189

Query: 352 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 407
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240

Query: 408 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295


>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
          Length = 298

 Score =  115 bits (287), Expect = 1e-25
 Identities = 89/296 (30%), Positives = 149/296 (50%), Gaps = 32/296 (10%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASRS-----NNMGIVGGFTQMIREGGARS 241
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GIV    ++ +E G  S
Sbjct: 10  KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69

Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 296
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T         L +G  AGA +  
Sbjct: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129

Query: 297 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
            +YP++  +TR+A  + K+G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189

Query: 352 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 407
               VY+T K            DP     V   +   T+++  G + SYP   VR RM  
Sbjct: 190 AYFGVYDTAKGM--------LPDPKNTHIVVSWMIAQTVTAVAG-VVSYPFDTVRRRMMM 240

Query: 408 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           Q+  +GA  +   ++  ++ I R EG    ++G   N ++ +    +  V+Y+ LK
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDELK 295



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 46/197 (23%), Positives = 90/197 (45%), Gaps = 10/197 (5%)

Query: 275 QETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTG-------QYSGMLDCARRIL 327
           ++ +   +  +AG +A AI+++++ P+E +K  + ++          QY G++DC  RI 
Sbjct: 3   EQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIP 62

Query: 328 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTM 386
             +GV +F++G + N++   P   ++ A  +  K  +L     ++     F   LA G  
Sbjct: 63  KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGA 122

Query: 387 SSTCGQLASYPLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFM 444
           +        YPL   RTR+ A     G       +      I +++G  GLY+G + +  
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQ 182

Query: 445 KVIPAVSISYVVYENLK 461
            +I   +  + VY+  K
Sbjct: 183 GIIIYRAAYFGVYDTAK 199


>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score =  115 bits (287), Expect = 1e-25
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139

Query: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199

Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259

Query: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137

Query: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193

Query: 455 VVYENLK 461
             Y +LK
Sbjct: 194 SCYSSLK 200



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180

Query: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237

Query: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297

Query: 352 IDLAVYETLKNAW 364
                YE   N +
Sbjct: 298 FMFFSYEFFCNVF 310



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277

Query: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265
           A   ++G   ++LK A  +   F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304


>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score =  115 bits (287), Expect = 1e-25
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139

Query: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199

Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259

Query: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137

Query: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193

Query: 455 VVYENLK 461
             Y +LK
Sbjct: 194 SCYSSLK 200



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180

Query: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237

Query: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297

Query: 352 IDLAVYETLKNAW 364
                YE   N +
Sbjct: 298 FMFFSYEFFCNVF 310



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277

Query: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265
           A   ++G   ++LK A  +   F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304


>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score =  115 bits (287), Expect = 1e-25
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139

Query: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199

Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259

Query: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137

Query: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193

Query: 455 VVYENLK 461
             Y +LK
Sbjct: 194 SCYSSLK 200



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180

Query: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237

Query: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297

Query: 352 IDLAVYETLKNAW 364
                YE   N +
Sbjct: 298 FMFFSYEFFCNVF 310



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277

Query: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265
           A   ++G   ++LK A  +   F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304


>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
          Length = 315

 Score =  113 bits (283), Expect = 3e-25
 Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 17/286 (5%)

Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS---RSNNMGIVGGFTQMIREGGARSLW 243
           + +L+AG   G +S     PLD +K+   V      R    GI+   T + +  G R L+
Sbjct: 23  YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82

Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLVGSDQ-ETLRIHERLVAGSLAGAIAQSSIYPME 302
           +G   N+        + F  Y  IK      + E L   E LV+ + AGA+      P+ 
Sbjct: 83  QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLW 142

Query: 303 VLKTRMALRKTG-------QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
           V KTR+ L+          QY GM D   +I   EGV   YKG+VP + G   +  +   
Sbjct: 143 VTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFM 201

Query: 356 VYETLKNAWLQHY-AVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGA 414
            YE LK  + QH   +  A       ++   +S      A+YP  +VR R+Q Q      
Sbjct: 202 AYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG 261

Query: 415 PEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
               +  +     R EG  G Y+G+APN ++V PA  I++VVYEN+
Sbjct: 262 ----VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENV 303



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 49/185 (26%), Positives = 90/185 (48%), Gaps = 13/185 (7%)

Query: 189 HLVAGGGAGAVSRTCTAPL--DRLKVLMQ----VHASRSNNMGIVGGFTQMIREGGARSL 242
           +LV+   AGA++   T PL   + ++++Q    V++      G+     ++ +  G R L
Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGL 182

Query: 243 WRGNGINVLKIAPESAIKFMAYEQIKRLVGSD-----QETLRIHERLVAGSLAGAIAQSS 297
           ++G  +  L      A++FMAYE +K           +  L   E +   +L+   A ++
Sbjct: 183 YKGF-VPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAA 241

Query: 298 IYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVY 357
            YP +V++ R+  +    YSG++D   +   +EGV  FYKG  PN++ + P   I   VY
Sbjct: 242 TYPYQVVRARLQDQHMF-YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVY 300

Query: 358 ETLKN 362
           E + +
Sbjct: 301 ENVSH 305



 Score = 32.3 bits (72), Expect = 0.95
 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 1/82 (1%)

Query: 381 LACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT-MSSLFKHILRTEGAFGLYRGL 439
           L  G        LA +PL LV+ R      +E  P+   +      I + +G  GLY+G+
Sbjct: 26  LIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGV 85

Query: 440 APNFMKVIPAVSISYVVYENLK 461
            PN      +  + +  Y  +K
Sbjct: 86  TPNIWGAGLSWGLYFFFYNAIK 107



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 11/47 (23%), Positives = 24/47 (51%)

Query: 225 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLV 271
           G++   T+  R+ G    ++G   N++++ P   I F+ YE +   +
Sbjct: 261 GVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307


>gi|55749577 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 4 [Homo
           sapiens]
          Length = 298

 Score =  113 bits (282), Expect = 4e-25
 Identities = 84/292 (28%), Positives = 144/292 (49%), Gaps = 24/292 (8%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASRSNNM-----GIVGGFTQMIREGGARS 241
           +  +AGG A AVS+T  AP++R+K+L+QV HAS+  +      GI+    ++ +E G  S
Sbjct: 10  KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69

Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 296
            WRGN  NV++  P  A+ F   ++ K+L     +  +   R  AG+L     AGA +  
Sbjct: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129

Query: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
            +YP++  +TR+A          ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189

Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
               VY+T K        V+     +FV        +    L SYP   VR RM  Q+  
Sbjct: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244

Query: 412 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           +GA  +   ++  ++ I + EGA   ++G   N ++ +    +  V+Y+ +K
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295


>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
           sapiens]
          Length = 311

 Score =  108 bits (271), Expect = 8e-24
 Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 41/303 (13%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 230
           HL AGG  G V    T PL+ +K  +Q                     +R  + G +   
Sbjct: 9   HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68

Query: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 288
             ++ + G RSL+RG G N++ +AP  AI F AY   K  +    D ++ ++H  +++ +
Sbjct: 69  KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126

Query: 289 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
           +AG  A ++  P+ ++KTR+ L  R  G+   G  +C R++   +G+  FY+G   +  G
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186

Query: 346 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 395
           I     I   +YE++K   L++           +V  A   V ++LA  T S TC    +
Sbjct: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244

Query: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
           YP  +VRTR++     EG    +       +++ EG   LYRGL  + ++ IP  +I   
Sbjct: 245 YPHEVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 300

Query: 456 VYE 458
            YE
Sbjct: 301 TYE 303



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)

Query: 379 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 422
           V L  G    T G + + PL +V+TR+Q+ +      EV ++++                
Sbjct: 8   VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67

Query: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
            K IL  EG   L+RGL PN + V P+ +I +  Y N K
Sbjct: 68  LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106


>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
           sapiens]
          Length = 325

 Score =  106 bits (264), Expect = 5e-23
 Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)

Query: 177 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 232
           TV    +G+ W+  V GG A  V+   T P+D  K  +QV      +R   +   G F  
Sbjct: 31  TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90

Query: 233 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 287
           + R   E G  +L+ G    +L+ A    IK   Y+ +KRL     + ETL I+  ++ G
Sbjct: 91  LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148

Query: 288 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 347
            ++G I+ +   P +VLK RM  + +     M+     I  +EG    ++G VP      
Sbjct: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208

Query: 348 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 406
              G++L VY+  K   +    +       FV    CG      G LAS P+ +VRTRM 
Sbjct: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264

Query: 407 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
            Q +I G  ++   T+  + K + + EG F LY+G  PN++++ P   I ++ YE LK
Sbjct: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 244
           H V+    G      + P+D ++  M    +   ++    G V G  +M +  G  +L++
Sbjct: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297

Query: 245 GNGINVLKIAPESAIKFMAYEQIKRL 270
           G   N L++ P + I F+ YEQ+KRL
Sbjct: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323


>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
           sapiens]
          Length = 322

 Score =  106 bits (264), Expect = 5e-23
 Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)

Query: 177 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 232
           TV    +G+ W+  V GG A  V+   T P+D  K  +QV      +R   +   G F  
Sbjct: 28  TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 87

Query: 233 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 287
           + R   E G  +L+ G    +L+ A    IK   Y+ +KRL     + ETL I+  ++ G
Sbjct: 88  LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 145

Query: 288 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 347
            ++G I+ +   P +VLK RM  + +     M+     I  +EG    ++G VP      
Sbjct: 146 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 205

Query: 348 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 406
              G++L VY+  K   +    +       FV    CG      G LAS P+ +VRTRM 
Sbjct: 206 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 261

Query: 407 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
            Q +I G  ++   T+  + K + + EG F LY+G  PN++++ P   I ++ YE LK
Sbjct: 262 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 244
           H V+    G      + P+D ++  M    +   ++    G V G  +M +  G  +L++
Sbjct: 235 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 294

Query: 245 GNGINVLKIAPESAIKFMAYEQIKRL 270
           G   N L++ P + I F+ YEQ+KRL
Sbjct: 295 GFWPNWLRLGPWNIIFFITYEQLKRL 320


>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
           sapiens]
          Length = 310

 Score =  105 bits (261), Expect = 1e-22
 Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 230
           HL AGG  G V    T PL+ +K  +Q                     +R  + G +   
Sbjct: 9   HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68

Query: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 288
             ++ + G RSL+RG G N++ +AP  AI F AY   K  +    D ++ ++H  +++ +
Sbjct: 69  KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126

Query: 289 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
           +AG  A ++  P+ ++KTR+ L  R  G+   G  +C R++   +G+  FY+G   +  G
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186

Query: 346 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 395
           I     I   +YE++K   L++           +V  A   V ++LA  T S TC    +
Sbjct: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244

Query: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
           YP  +VRTR++     EG    +       +++ EG   LYRGL  + ++ IP  +I   
Sbjct: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299

Query: 456 VYE 458
            YE
Sbjct: 300 TYE 302



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)

Query: 379 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 422
           V L  G    T G + + PL +V+TR+Q+ +      EV ++++                
Sbjct: 8   VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67

Query: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
            K IL  EG   L+RGL PN + V P+ +I +  Y N K
Sbjct: 68  LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106


>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
          Length = 321

 Score =  102 bits (253), Expect = 1e-21
 Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 229
           HL AGG  G V    T PL+ +K  +Q             VH    +  G+V       G
Sbjct: 14  HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73

Query: 230 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 284
             Q+++    + G +SL+RG G N++ +AP  A+ F  Y + K +  G       I    
Sbjct: 74  LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133

Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 341
            AGS A  I  S + P+ ++KTRM L    +  +    L CAR +   EG+  FY+G   
Sbjct: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192

Query: 342 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 395
           +  GI     I  A+YE+LK    +    +SA+         F L+A   +S  C    +
Sbjct: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251

Query: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
           YP  ++RTR++     EG    +     + + R EG    YRGL    ++ IP  +I   
Sbjct: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307

Query: 456 VYE 458
            YE
Sbjct: 308 TYE 310



 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)

Query: 272 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 309
           G  +E   +H  L AG   G +      P+EV+KTR+                       
Sbjct: 5   GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62

Query: 310 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
             +R T    G+    + IL +EG  + ++G  PN++G+ P   +  A Y   K  +   
Sbjct: 63  GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122

Query: 368 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 427
           +  NS    +  + + G+ +     L + P+ +V+TRMQ +  + G+ ++      +++ 
Sbjct: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178

Query: 428 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           +TEG  G YRGL  ++  +   + I + +YE+LK
Sbjct: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
           H+ + G A  ++ +   P+  +K  MQ+      S  M  +     + +  G R  +RG 
Sbjct: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190

Query: 247 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 296
             +   I+ E+ I F  YE +K+ +          G+++ +      + A +L+   A  
Sbjct: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249

Query: 297 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
             YP EV++TR  LR+ G +Y   +  AR +   EG  AFY+G    ++  IP   I L+
Sbjct: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307

Query: 356 VYETL 360
            YE +
Sbjct: 308 TYELI 312


>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
          Length = 291

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)

Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 239
           W+  V GG A   +   T P+D  K  +Q+    ++         G++    ++ RE G 
Sbjct: 6   WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65

Query: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 299
           ++L+ G    +L+ A    IK   Y+ +KRL     E   +   ++ G L+G I+ +   
Sbjct: 66  KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125

Query: 300 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 358
           P +VLK RM  +      GM+     I  +EG    +KG            G++L VY+ 
Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185

Query: 359 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 418
           T K+  L     ++          CG      G LAS P+ +VRTRM  Q  +       
Sbjct: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241

Query: 419 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
            +     +L+T   EG F LY+G  PN++++ P   I +V YE LK
Sbjct: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)

Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 239
           + H ++    G      + P+D ++  M     R    G   G+T       Q  +  G 
Sbjct: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258

Query: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 270
            +L++G   N L++ P + I F+ YEQ+K+L
Sbjct: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289


>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
          Length = 338

 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
           H+ AG  AG +  +   P+D +K  MQ  +   ++    I G   +++R  G     RG 
Sbjct: 48  HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107

Query: 247 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 303
            + ++   P  A+ F  YE +KR + +D    + +  L   +AGS+A  +  + + P EV
Sbjct: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166

Query: 304 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 363
           +K R+ +  + Q+   + C R +   EG+ AFY+ Y   +   IP+  I    YE L+  
Sbjct: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225

Query: 364 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 416
              H   N         +  G ++      A+ PL + +T +  Q       A+I G   
Sbjct: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280

Query: 417 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
             M++ F+ + +  G  G ++G+    +  +P+ +IS+ VYE  K  L
Sbjct: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)

Query: 280 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 336
           +   + AG++AG +  S +YP++ +KTRM   +     QY+ +    ++I+  EG     
Sbjct: 45  VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104

Query: 337 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 393
           +G    ++G  P   +  A YE +K   N    H   +    G+      G+M++     
Sbjct: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159

Query: 394 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 453
              P  +V+ R+Q    +  +   +  S  + + RTEG    YR         IP  SI 
Sbjct: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215

Query: 454 YVVYENLK 461
           ++ YE L+
Sbjct: 216 FITYEFLQ 223


>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
           sapiens]
          Length = 314

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)

Query: 187 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
           W HL      V G     + R    P   ++  +QV   +S   G    F +++R  G  
Sbjct: 12  WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71

Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
            L+RG  +N   +          YE  ++ V    ++  + + LVAG  A  +AQS   P
Sbjct: 72  GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129

Query: 301 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 342
           ++V+   + +++ G+  G                    D  R+IL  +G+  FY+GYV +
Sbjct: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189

Query: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
           +L  IP + +    Y     A    Y      P +      G +++    + + P+ ++R
Sbjct: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247

Query: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           TR+Q    +EG   + ++  F+ ++  EG +GL +GL+   +   P+  +  V YE+LK
Sbjct: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)

Query: 188 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 230
           + LVAGG A  V+++ T P+D +   ++MQ    +     + G                 
Sbjct: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170

Query: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 286
            Q+++  G R  +RG   ++L   P SA+ +  Y    EQ+  L    +E   I  + V+
Sbjct: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228

Query: 287 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 346
           G LA A A     PM+V++TR+ +   G+ S +L   R+++A EG     KG    ++  
Sbjct: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285

Query: 347 IPYAGIDLAVYETLKNAWLQHYAVNS 372
            P   + +  YE+LK   L+   V+S
Sbjct: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311


>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
          Length = 364

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 77/289 (26%), Positives = 126/289 (43%), Gaps = 29/289 (10%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRSNNMGIVGGFTQMIREGGARSLWR 244
           H+VAG  AG +      P+D +K  MQ      A+R  N  ++    ++IR  G     R
Sbjct: 75  HMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRN--VLEALWRIIRTEGLWRPMR 132

Query: 245 GNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH---ERLVAGSLAGAIA----QSS 297
           G  +      P  A+ F  YE++K+ +        IH      +A   AG +A     ++
Sbjct: 133 GLNVTATGAGPAHALYFACYEKLKKTLSDV-----IHPGGNSHIANGAAGCVATLLHDAA 187

Query: 298 IYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVY 357
           + P EV+K RM +  +  Y  + DC R +   EG  AFY+ Y   +   +P+  I    Y
Sbjct: 188 MNPAEVVKQRMQMYNS-PYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTY 246

Query: 358 ETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEV 417
           E L+  +      N   P   VL   G  +      A+ PL + +T +  Q S+     +
Sbjct: 247 EFLQEHFNPQRRYN---PSSHVL--SGACAGAVAAAATTPLDVCKTLLNTQESLALNSHI 301

Query: 418 T-----MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
           T     M+S F+ + +  G    +RG+    +  IP+ +I++ VYE  K
Sbjct: 302 TGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFK 350



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 51/205 (24%), Positives = 85/205 (41%), Gaps = 13/205 (6%)

Query: 272 GSDQETL----RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRK---TGQYSGMLDCAR 324
           G D E L     +   +VAG++AG +    +YP++ +KTRM   +     +Y  +L+   
Sbjct: 60  GPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALW 119

Query: 325 RILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACG 384
           RI+  EG+    +G      G  P   +  A YE LK        ++          A G
Sbjct: 120 RIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSD--VIHPGGNSHIANGAAG 177

Query: 385 TMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFM 444
            +++     A  P  +V+ RMQ   S    P   ++   + + + EGA   YR       
Sbjct: 178 CVATLLHDAAMNPAEVVKQRMQMYNS----PYHRVTDCVRAVWQNEGAGAFYRSYTTQLT 233

Query: 445 KVIPAVSISYVVYENLKITLGVQSR 469
             +P  +I ++ YE L+     Q R
Sbjct: 234 MNVPFQAIHFMTYEFLQEHFNPQRR 258



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMI-------REGGARS 241
           H+++G  AGAV+   T PLD  K L+    S + N  I G  T M        + GG  +
Sbjct: 264 HVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTA 323

Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLR 279
            +RG    V+   P +AI +  YE  K L+   QE  R
Sbjct: 324 YFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWR 361


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,101,994
Number of Sequences: 37866
Number of extensions: 674281
Number of successful extensions: 2740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 1794
Number of HSP's gapped (non-prelim): 542
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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