Guide to the Human Genome
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Search of human proteins with 239755066

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755066 PREDICTED: similar to tight junction protein 2
(zona occludens 2) [Homo sapiens]
         (163 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755066 PREDICTED: similar to tight junction protein 2 (zon...   335   8e-93
gi|239749588 PREDICTED: hypothetical protein XP_002347097 [Homo ...   335   8e-93
gi|239743857 PREDICTED: hypothetical protein XP_002342979 [Homo ...   333   3e-92
gi|46410931 attractin-like 1 [Homo sapiens]                            28   2.7  
gi|40254988 LSM domain containing 1 [Homo sapiens]                     28   2.7  
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]              28   3.5  
gi|21717832 sperm equatorial segment protein 1 [Homo sapiens]          28   3.5  
gi|115511057 hypothetical protein LOC256643 [Homo sapiens]             28   4.6  
gi|54607051 glucocerebrosidase precursor [Homo sapiens]                27   7.8  
gi|54607049 glucocerebrosidase precursor [Homo sapiens]                27   7.8  
gi|54607047 glucocerebrosidase precursor [Homo sapiens]                27   7.8  
gi|54607045 glucocerebrosidase precursor [Homo sapiens]                27   7.8  
gi|54607043 glucocerebrosidase precursor [Homo sapiens]                27   7.8  
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...    27   7.8  
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...    27   7.8  

>gi|239755066 PREDICTED: similar to tight junction protein 2 (zona
           occludens 2) [Homo sapiens]
          Length = 163

 Score =  335 bits (860), Expect = 8e-93
 Identities = 163/163 (100%), Positives = 163/163 (100%)

Query: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60
           MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK
Sbjct: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60

Query: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120
           RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS
Sbjct: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120

Query: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163
           VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV
Sbjct: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163


>gi|239749588 PREDICTED: hypothetical protein XP_002347097 [Homo
           sapiens]
          Length = 163

 Score =  335 bits (860), Expect = 8e-93
 Identities = 163/163 (100%), Positives = 163/163 (100%)

Query: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60
           MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK
Sbjct: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60

Query: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120
           RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS
Sbjct: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120

Query: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163
           VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV
Sbjct: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163


>gi|239743857 PREDICTED: hypothetical protein XP_002342979 [Homo
           sapiens]
          Length = 163

 Score =  333 bits (855), Expect = 3e-92
 Identities = 162/163 (99%), Positives = 162/163 (99%)

Query: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60
           MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK
Sbjct: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60

Query: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120
           RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQ EPS
Sbjct: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS 120

Query: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163
           VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV
Sbjct: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163


>gi|46410931 attractin-like 1 [Homo sapiens]
          Length = 1379

 Score = 28.5 bits (62), Expect = 2.7
 Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 31   ACTFKMLALLKAVW-VLHVAWDSKGKEEAAKRQLLMRKNSYCFLIYILQVRKQNTDF--G 87
            +C   +L +   VW +    W S+ +E+  + +  M    +  +   L+V  + T+F  G
Sbjct: 1239 SCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRG 1298

Query: 88   PLK 90
            PL+
Sbjct: 1299 PLE 1301


>gi|40254988 LSM domain containing 1 [Homo sapiens]
          Length = 173

 Score = 28.5 bits (62), Expect = 2.7
 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 11/100 (11%)

Query: 45  VLHVAWDSKGKEE--AAKRQLLMRKNSYCFLIYILQVRKQNTDFGPLKQV---TGSDCSV 99
           +LH A DS G+ E  AA+R    R+     L   +++R   TD   L      T  DC+V
Sbjct: 70  LLHPAQDSDGEREDSAAERA---RQQLEALLNKTMRIRM--TDGRTLVGCFLCTDRDCNV 124

Query: 100 LLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTHELE 139
           +L S Q+    S+     EP VL L  + PG  + + E++
Sbjct: 125 ILGSAQEFLKPSDSFSAGEPRVLGL-AMVPGHHIVSIEVQ 163


>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
          Length = 636

 Score = 28.1 bits (61), Expect = 3.5
 Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 3/64 (4%)

Query: 86  FGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTHELESHHVSM 145
           F PL ++TG D +V  +    A  S  P P  +P        S  F + T E ++   S 
Sbjct: 83  FDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSG---TSSEFEVVTPEEQNSPESS 139

Query: 146 VHSN 149
            H+N
Sbjct: 140 SHAN 143


>gi|21717832 sperm equatorial segment protein 1 [Homo sapiens]
          Length = 350

 Score = 28.1 bits (61), Expect = 3.5
 Identities = 10/41 (24%), Positives = 26/41 (63%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120
           +K++T+  P   +  ++ S++L++E+   ++  P P+ EP+
Sbjct: 112 KKKHTESTPFWSIKPNNVSIVLHAEEPYIENEEPEPEPEPA 152


>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
          Length = 682

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 96  DCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLS 128
           DC    NS     D S  +P ++PS +NL + S
Sbjct: 378 DCRKESNSSSNQLDKSQKLPDVKPSPINLRKKS 410


>gi|54607051 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607049 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607047 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607045 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607043 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 20  ETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSK----GKEEAAKRQLLMRKNSYCFLIY 75
           +TH      PSA T K+L LL     ++ A+ +K     KE A  RQ +  K     L +
Sbjct: 492 DTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQ-VGNKTECALLGF 550

Query: 76  ILQVRKQNTDFGPLKQVTGSD 96
           +L +++   DF P+++    D
Sbjct: 551 VLDLKR---DFQPVREQIPED 568


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
           sapiens]
          Length = 1173

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 20  ETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSK----GKEEAAKRQLLMRKNSYCFLIY 75
           +TH      PSA T K+L LL     ++ A+ +K     KE A  RQ +  K     L +
Sbjct: 492 DTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQ-VGNKTECALLGF 550

Query: 76  ILQVRKQNTDFGPLKQVTGSD 96
           +L +++   DF P+++    D
Sbjct: 551 VLDLKR---DFQPVREQIPED 568


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.129    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,855,560
Number of Sequences: 37866
Number of extensions: 287693
Number of successful extensions: 598
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 593
Number of HSP's gapped (non-prelim): 15
length of query: 163
length of database: 18,247,518
effective HSP length: 94
effective length of query: 69
effective length of database: 14,688,114
effective search space: 1013479866
effective search space used: 1013479866
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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