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Search of human proteins with 118722349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118722349 RNA binding motif protein 12B [Homo sapiens]
(1001 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118722349 RNA binding motif protein 12B [Homo sapiens] 2100 0.0
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 199 1e-50
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 199 1e-50
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 103 1e-21
gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Hom... 89 3e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 87 6e-17
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap... 85 4e-16
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi... 85 4e-16
gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo sapi... 83 1e-15
gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Hom... 83 1e-15
gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens] 77 6e-14
gi|148746195 trichohyalin [Homo sapiens] 77 8e-14
gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b... 77 8e-14
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap... 74 9e-13
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap... 74 9e-13
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap... 74 9e-13
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap... 74 9e-13
gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo sap... 74 9e-13
gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens] 74 9e-13
gi|45935393 RNA binding motif protein 35B [Homo sapiens] 74 9e-13
gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a... 74 9e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 69 2e-11
gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens] 68 5e-11
gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens] 68 5e-11
gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens] 68 5e-11
gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens] 68 5e-11
gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens] 68 5e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 65 2e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 65 2e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 65 2e-10
>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
Length = 1001
Score = 2100 bits (5442), Expect = 0.0
Identities = 1001/1001 (100%), Positives = 1001/1001 (100%)
Query: 1 MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRS 60
MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRS
Sbjct: 1 MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRS 60
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS
Sbjct: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV 180
GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV
Sbjct: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV 180
Query: 181 DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNA 240
DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNA
Sbjct: 181 DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNA 240
Query: 241 VKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDL 300
VKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDL
Sbjct: 241 VKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDL 300
Query: 301 RNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISR 360
RNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISR
Sbjct: 301 RNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISR 360
Query: 361 KQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFF 420
KQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFF
Sbjct: 361 KQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFF 420
Query: 421 ADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQI 480
ADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQI
Sbjct: 421 ADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQI 480
Query: 481 QEFGVNFSVMSSEKMQARSQSRERGDHSHLFDSKDPPIYSVGAFENFRHQLEDLRQLDNF 540
QEFGVNFSVMSSEKMQARSQSRERGDHSHLFDSKDPPIYSVGAFENFRHQLEDLRQLDNF
Sbjct: 481 QEFGVNFSVMSSEKMQARSQSRERGDHSHLFDSKDPPIYSVGAFENFRHQLEDLRQLDNF 540
Query: 541 KHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWE 600
KHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWE
Sbjct: 541 KHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWE 600
Query: 601 EDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLR 660
EDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLR
Sbjct: 601 EDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLR 660
Query: 661 WLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQ 720
WLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQ
Sbjct: 661 WLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQ 720
Query: 721 EHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFR 780
EHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFR
Sbjct: 721 EHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFR 780
Query: 781 RPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSD 840
RPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSD
Sbjct: 781 RPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSD 840
Query: 841 EDFRQLPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDFGK 900
EDFRQLPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDFGK
Sbjct: 841 EDFRQLPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDFGK 900
Query: 901 HNMGSFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYN 960
HNMGSFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYN
Sbjct: 901 HNMGSFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYN 960
Query: 961 EQGLPTGEAIVAMINYNEAMAAIKDLNDRPVGPRKVKLTLL 1001
EQGLPTGEAIVAMINYNEAMAAIKDLNDRPVGPRKVKLTLL
Sbjct: 961 EQGLPTGEAIVAMINYNEAMAAIKDLNDRPVGPRKVKLTLL 1001
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 199 bits (505), Expect = 1e-50
Identities = 120/348 (34%), Positives = 195/348 (56%), Gaps = 19/348 (5%)
Query: 146 KTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCV 205
K P+ ++ Y+ + G+P+ E+DVR FF GL VD V LK H GRNNG+ +VKF S
Sbjct: 295 KPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQ 354
Query: 206 DASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFR 265
D LK +R M R++EV +E+QW+ GG+ + ++ + H PP+ +
Sbjct: 355 DTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTL------ 408
Query: 266 KRSHSKSP---RRTRSRSP--LGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKD 320
SKSP +R+RSRSP GF V+LK L + + + +FF+ D+ ++ I Y
Sbjct: 409 --PRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGP 466
Query: 321 ENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLE 379
+ T FV F+ DY AL HK + R + + PI++K ML+ I +KR +
Sbjct: 467 NGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMI-RKRLQNFS 525
Query: 380 RDRPGHVSQKYSQEGN-SGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKG 438
D+ + + EG+ + K+C +I N PF +TK++V +F + E+ +++L D+ G
Sbjct: 526 YDQREMI---LNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNG 582
Query: 439 VGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVN 486
GLG+ALV+FK+E+ A K+ERL+R++ G E + +++ ++E N
Sbjct: 583 QGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKN 630
Score = 129 bits (325), Expect = 1e-29
Identities = 63/87 (72%), Positives = 72/87 (82%)
Query: 1 MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRS 60
MAVVIRL GLP +AG +DIRHFF+GLTIPDGGVHI+GGE+GEAFI+FATDEDAR + R+
Sbjct: 1 MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKR 87
GG IK S V L LSSK EMQ IE+ R
Sbjct: 61 GGTIKGSKVTLLLSSKTEMQNMIELSR 87
Score = 103 bits (256), Expect = 1e-21
Identities = 49/88 (55%), Positives = 67/88 (76%), Gaps = 2/88 (2%)
Query: 915 PKINCGSGRVTP--IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVA 972
P SG+ P IK+ N+PF +++EILDFF+GY++IP SV ++YNE+G+PTGEA+VA
Sbjct: 844 PGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVA 903
Query: 973 MINYNEAMAAIKDLNDRPVGPRKVKLTL 1000
+ +EA AA+ DLNDRP+G RKVKL L
Sbjct: 904 FESRDEATAAVIDLNDRPIGSRKVKLVL 931
Score = 61.6 bits (148), Expect = 4e-09
Identities = 53/216 (24%), Positives = 91/216 (42%), Gaps = 17/216 (7%)
Query: 269 HSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YA 327
+S+S + +P YV + + S E D+R+FF G L + + L R
Sbjct: 289 NSQSSVKPLPINPDDLYVSVHGMPFSAMENDVRDFFHG--LRVDAVHLLKDHVGRNNGNG 346
Query: 328 FVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYE-KKRSGSLERDRPGHV 386
V F + +D AL ++ ++ R V + P + +Q + K+ G + P
Sbjct: 347 LVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQ 406
Query: 387 SQKYSQEGNSGQK-----------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYD 435
+ S + SGQK C+Y++ PF+ V FF + ED IY+ Y
Sbjct: 407 TLPRS-KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYG 465
Query: 436 DKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVL 471
G GE V+F++E KA ++++G +
Sbjct: 466 PNGKATGEGFVEFRNEAD-YKAALCRHKQYMGNRFI 500
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/384 (21%), Positives = 148/384 (38%), Gaps = 54/384 (14%)
Query: 9 GLPFIAGPVDIRHFFTGLTIPDGGVHI----IGGEIGEAFIIFATDEDARRAISRSGGFI 64
G+PF A D+R FF GL + VH+ +G G + F + +D A+ R+ +
Sbjct: 310 GMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLM 367
Query: 65 KDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGS 124
VE+ T+R G T K+ SG
Sbjct: 368 IQRYVEV-------------SPATERQWVAAGGHIT------------FKQNMGPSGQTH 402
Query: 125 SINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DG 182
Q + + G R R P +A ++L+GLP+ V FF L + D
Sbjct: 403 PPPQT--LPRSKSPSGQKRSRSRSPHEA-GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS 459
Query: 183 VIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVK 242
+ +G+ G+ V+F + D L H+ +MG+RFI+V +++ +E
Sbjct: 460 IYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLE------- 512
Query: 243 EGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRN 302
+ D++R+ + + + +R +P + + + H+ N+ SI + D+
Sbjct: 513 KIDMIRKR--------LQNFSYDQREMILNPEGDVNSAKV--CAHITNIPFSITKMDVLQ 562
Query: 303 FFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRK 361
F G + + + L + + A V FK D + LH+ L R + ++ +
Sbjct: 563 FLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLE 622
Query: 362 QMLKFIARYEKKRSGSLERDRPGH 385
M + + L+ PG+
Sbjct: 623 DMREIEKNPPAQGKKGLKMPVPGN 646
Score = 44.7 bits (104), Expect = 4e-04
Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 50/239 (20%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+ L GLPF A + FF L I + ++I G GE F+ F + D + A+ R
Sbjct: 432 VYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRH 491
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
++ + +++ +K M + I+M R L NF +E N
Sbjct: 492 KQYMGNRFIQVHPITKKGMLEKIDMIR----------------KRLQNFSYDQREMILNP 535
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV 180
G++ K + +P+ + + DV F G+ V
Sbjct: 536 ------------------EGDVNSAKV--------CAHITNIPFSITKMDVLQFLEGIPV 569
Query: 181 D--GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSR--FIEVMQGSEQQWIE 235
D V L ++G+ G A+V+F + DA + HR + R F+ V+ + + IE
Sbjct: 570 DENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIE 628
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Query: 391 SQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
S G G + I ++N PF V+ E+ FF + + + L Y++KG+ GEA+V F+S
Sbjct: 848 SSSGKPGPTV-IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFES 906
Query: 451 EEQAMKA 457
++A A
Sbjct: 907 RDEATAA 913
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 14/104 (13%)
Query: 893 GGKFDFGKHNMG----SFPEGRFMPDPKINCGSGRVTP---------IKIMNLPFKANVN 939
GG F K NMG + P + +P K G R + + LPF+A
Sbjct: 386 GGHITF-KQNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENK 444
Query: 940 EILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
++DFF I+ DS+ I Y G TGE V N + AA+
Sbjct: 445 HVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
Score = 37.7 bits (86), Expect = 0.054
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
+ + +PF A N++ DFFHG R+ D+V + + G G +V ++ + A+K
Sbjct: 306 VSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALK 361
Score = 35.8 bits (81), Expect = 0.21
Identities = 15/58 (25%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRA 56
V + +PF +D+ F G+ + + VH++ G +G+A + F ++DAR++
Sbjct: 544 VCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKS 601
Score = 34.7 bits (78), Expect = 0.46
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCV-DGVIFLKHHDGRNNGDAIVKFASCVDASGGL 211
L+GLP + D+R FFSGL + DG + H G G+A + FA+ DA G+
Sbjct: 7 LQGLPIVAGTMDIRHFFSGLTIPDGGV---HIVGGELGEAFIVFATDEDARLGM 57
Score = 32.3 bits (72), Expect = 2.3
Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 905 SFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGL 964
S+ + + +P+ + S +V I N+PF ++L F G + ++V + + G
Sbjct: 525 SYDQREMILNPEGDVNSAKVCA-HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQ 583
Query: 965 PTGEAIVAMINYNEA 979
G+A+V N ++A
Sbjct: 584 GLGQALVQFKNEDDA 598
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 199 bits (505), Expect = 1e-50
Identities = 120/348 (34%), Positives = 195/348 (56%), Gaps = 19/348 (5%)
Query: 146 KTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCV 205
K P+ ++ Y+ + G+P+ E+DVR FF GL VD V LK H GRNNG+ +VKF S
Sbjct: 295 KPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQ 354
Query: 206 DASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFR 265
D LK +R M R++EV +E+QW+ GG+ + ++ + H PP+ +
Sbjct: 355 DTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTL------ 408
Query: 266 KRSHSKSP---RRTRSRSP--LGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKD 320
SKSP +R+RSRSP GF V+LK L + + + +FF+ D+ ++ I Y
Sbjct: 409 --PRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGP 466
Query: 321 ENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLE 379
+ T FV F+ DY AL HK + R + + PI++K ML+ I +KR +
Sbjct: 467 NGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMI-RKRLQNFS 525
Query: 380 RDRPGHVSQKYSQEGN-SGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKG 438
D+ + + EG+ + K+C +I N PF +TK++V +F + E+ +++L D+ G
Sbjct: 526 YDQREMI---LNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNG 582
Query: 439 VGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVN 486
GLG+ALV+FK+E+ A K+ERL+R++ G E + +++ ++E N
Sbjct: 583 QGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKN 630
Score = 129 bits (325), Expect = 1e-29
Identities = 63/87 (72%), Positives = 72/87 (82%)
Query: 1 MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRS 60
MAVVIRL GLP +AG +DIRHFF+GLTIPDGGVHI+GGE+GEAFI+FATDEDAR + R+
Sbjct: 1 MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKR 87
GG IK S V L LSSK EMQ IE+ R
Sbjct: 61 GGTIKGSKVTLLLSSKTEMQNMIELSR 87
Score = 103 bits (256), Expect = 1e-21
Identities = 49/88 (55%), Positives = 67/88 (76%), Gaps = 2/88 (2%)
Query: 915 PKINCGSGRVTP--IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVA 972
P SG+ P IK+ N+PF +++EILDFF+GY++IP SV ++YNE+G+PTGEA+VA
Sbjct: 844 PGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVA 903
Query: 973 MINYNEAMAAIKDLNDRPVGPRKVKLTL 1000
+ +EA AA+ DLNDRP+G RKVKL L
Sbjct: 904 FESRDEATAAVIDLNDRPIGSRKVKLVL 931
Score = 61.6 bits (148), Expect = 4e-09
Identities = 53/216 (24%), Positives = 91/216 (42%), Gaps = 17/216 (7%)
Query: 269 HSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YA 327
+S+S + +P YV + + S E D+R+FF G L + + L R
Sbjct: 289 NSQSSVKPLPINPDDLYVSVHGMPFSAMENDVRDFFHG--LRVDAVHLLKDHVGRNNGNG 346
Query: 328 FVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYE-KKRSGSLERDRPGHV 386
V F + +D AL ++ ++ R V + P + +Q + K+ G + P
Sbjct: 347 LVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQ 406
Query: 387 SQKYSQEGNSGQK-----------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYD 435
+ S + SGQK C+Y++ PF+ V FF + ED IY+ Y
Sbjct: 407 TLPRS-KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYG 465
Query: 436 DKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVL 471
G GE V+F++E KA ++++G +
Sbjct: 466 PNGKATGEGFVEFRNEAD-YKAALCRHKQYMGNRFI 500
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/384 (21%), Positives = 148/384 (38%), Gaps = 54/384 (14%)
Query: 9 GLPFIAGPVDIRHFFTGLTIPDGGVHI----IGGEIGEAFIIFATDEDARRAISRSGGFI 64
G+PF A D+R FF GL + VH+ +G G + F + +D A+ R+ +
Sbjct: 310 GMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLM 367
Query: 65 KDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGS 124
VE+ T+R G T K+ SG
Sbjct: 368 IQRYVEV-------------SPATERQWVAAGGHIT------------FKQNMGPSGQTH 402
Query: 125 SINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DG 182
Q + + G R R P +A ++L+GLP+ V FF L + D
Sbjct: 403 PPPQT--LPRSKSPSGQKRSRSRSPHEA-GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS 459
Query: 183 VIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVK 242
+ +G+ G+ V+F + D L H+ +MG+RFI+V +++ +E
Sbjct: 460 IYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLE------- 512
Query: 243 EGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRN 302
+ D++R+ + + + +R +P + + + H+ N+ SI + D+
Sbjct: 513 KIDMIRKR--------LQNFSYDQREMILNPEGDVNSAKV--CAHITNIPFSITKMDVLQ 562
Query: 303 FFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRK 361
F G + + + L + + A V FK D + LH+ L R + ++ +
Sbjct: 563 FLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLE 622
Query: 362 QMLKFIARYEKKRSGSLERDRPGH 385
M + + L+ PG+
Sbjct: 623 DMREIEKNPPAQGKKGLKMPVPGN 646
Score = 44.7 bits (104), Expect = 4e-04
Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 50/239 (20%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+ L GLPF A + FF L I + ++I G GE F+ F + D + A+ R
Sbjct: 432 VYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRH 491
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
++ + +++ +K M + I+M R L NF +E N
Sbjct: 492 KQYMGNRFIQVHPITKKGMLEKIDMIR----------------KRLQNFSYDQREMILNP 535
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV 180
G++ K + +P+ + + DV F G+ V
Sbjct: 536 ------------------EGDVNSAKV--------CAHITNIPFSITKMDVLQFLEGIPV 569
Query: 181 D--GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSR--FIEVMQGSEQQWIE 235
D V L ++G+ G A+V+F + DA + HR + R F+ V+ + + IE
Sbjct: 570 DENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIE 628
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Query: 391 SQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
S G G + I ++N PF V+ E+ FF + + + L Y++KG+ GEA+V F+S
Sbjct: 848 SSSGKPGPTV-IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFES 906
Query: 451 EEQAMKA 457
++A A
Sbjct: 907 RDEATAA 913
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 14/104 (13%)
Query: 893 GGKFDFGKHNMG----SFPEGRFMPDPKINCGSGRVTP---------IKIMNLPFKANVN 939
GG F K NMG + P + +P K G R + + LPF+A
Sbjct: 386 GGHITF-KQNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENK 444
Query: 940 EILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
++DFF I+ DS+ I Y G TGE V N + AA+
Sbjct: 445 HVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
Score = 37.7 bits (86), Expect = 0.054
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
+ + +PF A N++ DFFHG R+ D+V + + G G +V ++ + A+K
Sbjct: 306 VSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALK 361
Score = 35.8 bits (81), Expect = 0.21
Identities = 15/58 (25%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRA 56
V + +PF +D+ F G+ + + VH++ G +G+A + F ++DAR++
Sbjct: 544 VCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKS 601
Score = 34.7 bits (78), Expect = 0.46
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCV-DGVIFLKHHDGRNNGDAIVKFASCVDASGGL 211
L+GLP + D+R FFSGL + DG + H G G+A + FA+ DA G+
Sbjct: 7 LQGLPIVAGTMDIRHFFSGLTIPDGGV---HIVGGELGEAFIVFATDEDARLGM 57
Score = 32.3 bits (72), Expect = 2.3
Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 905 SFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGL 964
S+ + + +P+ + S +V I N+PF ++L F G + ++V + + G
Sbjct: 525 SYDQREMILNPEGDVNSAKVCA-HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQ 583
Query: 965 PTGEAIVAMINYNEA 979
G+A+V N ++A
Sbjct: 584 GLGQALVQFKNEDDA 598
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 103 bits (256), Expect = 1e-21
Identities = 88/351 (25%), Positives = 113/351 (32%), Gaps = 17/351 (4%)
Query: 541 KHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWE 600
+H + + + P +R + R P E RH+P + R PSE R E
Sbjct: 1528 RHLKDKLTHKEHNHPSFYRERTP--RGPSERTRHNPS------WRNHRSPSERSQRSSLE 1579
Query: 601 EDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLR 660
P + P ++ P E WR P + + P L E P + R
Sbjct: 1580 RRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHR 1639
Query: 661 WLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRP-------PEEDFRHSPEE 713
+ P E R P E R + R P + R P P E SP +
Sbjct: 1640 GPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQ 1699
Query: 714 DFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRR 773
+ P E P + R P R P E P E P E P E
Sbjct: 1700 RSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHC 1759
Query: 774 PPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFR-SPQE 832
P E P E R P E S E H P E P E RH P E R S E
Sbjct: 1760 SPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLE 1819
Query: 833 EDFRCPSDEDFRQLPEEDLREAPEEDPRLPD-NFRPPGEDFRSPPDDFRSH 882
R PS+ + E R E + + P E R P + R H
Sbjct: 1820 RSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGH 1870
Score = 95.9 bits (237), Expect = 2e-19
Identities = 105/406 (25%), Positives = 123/406 (30%), Gaps = 41/406 (10%)
Query: 522 GAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPED--F 579
G E RH + QR + H P H S P SP + +
Sbjct: 1552 GPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCS-----PSRKNHSSPSERSW 1606
Query: 580 RRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSP 639
R P + + P E E P + R P + P E R P E R S
Sbjct: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSS 1666
Query: 640 TEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDF 699
R + R P E E R P + R P E P + R P
Sbjct: 1667 ERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSH 1726
Query: 700 RRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPP 759
R P E HSP E SP E P E P E P E R P E P
Sbjct: 1727 RSPSERS-HHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSP 1785
Query: 760 PEHFRRPPPEHFRRPPPEHFRRPPQEH---------FRRPPQEHFRRSREEDFR------ 804
E P E P E R P E R P + RS E R
Sbjct: 1786 SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERS 1845
Query: 805 HPPDEDFRGPPDEDFRHPPDE---------DFRSPQEEDFRCPSDEDFRQLPEEDLREAP 855
H P E P E R P E SP E R PS + E R +
Sbjct: 1846 HSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
Query: 856 EEDPRLPDNF---RPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDF 898
E P RP G + SP + RS R + EG K+ F
Sbjct: 1906 ERTRHSPSEMRPGRPSGRNHCSPSE--RSRRSPLK----EGLKYSF 1945
>gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Homo
sapiens]
Length = 480
Score = 88.6 bits (218), Expect = 3e-17
Identities = 80/337 (23%), Positives = 135/337 (40%), Gaps = 74/337 (21%)
Query: 160 RGLPYLVNEDDVRVFFSGLCV----DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHR 215
+GLP+ +DV FFS + +G+ FL + DG+ GDA+++ S D L+ HR
Sbjct: 155 QGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHR 214
Query: 216 SFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRR 275
+MG R++EV + + + + D L +S + +ND
Sbjct: 215 MYMGQRYVEVYEINNE-----------DVDALMKSLQVKSSPVVNDG------------- 250
Query: 276 TRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLK 335
V L+ L S +E+D+ +FF G ++ D Y+ +T A+V F+ +
Sbjct: 251 ---------VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPE 301
Query: 336 DYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSL----------------- 378
N AL H+ + R + I P R ++ + Y+ K+ S
Sbjct: 302 MANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHE 361
Query: 379 ---------------ERDRPGHVSQKYSQE---GNSGQKLCIYIRNFPFDVTKVEVQKFF 420
E + P V +K + G + +++R PF ++ FF
Sbjct: 362 VNEDIQPMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF 421
Query: 421 ADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA 457
A L I + Y G GEA V F++ E A+ A
Sbjct: 422 AP--LKPVRITMEYSSSGKATGEADVHFETHEDAVAA 456
Score = 62.4 bits (150), Expect = 2e-09
Identities = 80/381 (20%), Positives = 145/381 (38%), Gaps = 89/381 (23%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
+IR GLP+ D+ +FF+ I +G G+H + G G+A I +++D ++A+
Sbjct: 151 LIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ ++ VE++ E+ D VD+L ++
Sbjct: 211 EKHRMYMGQRYVEVY-----------EINNED-------------VDALMKSLQVKSSPV 246
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
N G + LRGLPY NE D+ FF+G
Sbjct: 247 VNDGV----------------------------------VRLRGLPYSCNEKDIVDFFAG 272
Query: 178 LCVDGVIFLKHHDG-RNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ-WIE 235
L + + F+ + G R G+A V+F A+ L HR +G+R+IE+ +
Sbjct: 273 LNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTH 332
Query: 236 FGGNAVKEGDVLRRSEEHSPPRGINDRH-----------FRKRSHSKSPRRTRSRSPLG- 283
G K+ ++ + P + + H F + P+ + P
Sbjct: 333 VGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMTAFESEKEIELPKEVPEKLPEAA 392
Query: 284 --------FYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTL 334
+VH++ L + +D+ NFF L +I Y + T A V F+T
Sbjct: 393 DFGTTSSLHFVHMRGLPFQANAQDIINFF--APLKPVRITMEYSSSGKATGEADVHFETH 450
Query: 335 KDYNTALSLHKTVLQYRPVHI 355
+D A+ ++ + +R + +
Sbjct: 451 EDAVAAMLKDRSHVHHRYIEL 471
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/241 (24%), Positives = 96/241 (39%), Gaps = 31/241 (12%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPD-GGVHIIGG--EIGEAFIIFATDEDARRAISRS 60
V+RL GLP+ DI FF GL I D V G + GEA++ F E A +A+ +
Sbjct: 251 VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKH 310
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSL------------SN 108
I + +E+F S + E++ + + ++ + + +
Sbjct: 311 REEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMT 370
Query: 109 FIESVKEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNE 168
ES KE + + A F T + H ++ +RGLP+ N
Sbjct: 371 AFESEKEIELPKEVPEKLPEAADFGTTSSLH----------------FVHMRGLPFQANA 414
Query: 169 DDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQG 228
D+ FF+ L + G+ G+A V F + DA + RS + R+IE+
Sbjct: 415 QDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLN 474
Query: 229 S 229
S
Sbjct: 475 S 475
Score = 40.0 bits (92), Expect = 0.011
Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 4/63 (6%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+ + LPF+AN +I++FF + P ++++Y+ G TGEA V + +A+AA+ L
Sbjct: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAM--L 458
Query: 987 NDR 989
DR
Sbjct: 459 KDR 461
Score = 32.7 bits (73), Expect = 1.8
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 402 IYIRNFPFDVTKVEVQKFFADFLL--AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAER 459
I + P+ T +V FF+D + E+ I+ L + G G+AL++ +SE+ KA
Sbjct: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
Query: 460 LNR 462
+R
Sbjct: 212 KHR 214
Score = 30.8 bits (68), Expect = 6.7
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIV 971
+++ LP+ N +I+DFF G I+ + + Y + TGEA V
Sbjct: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGR-RKTGEAYV 295
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 87.4 bits (215), Expect = 6e-17
Identities = 97/277 (35%), Positives = 105/277 (37%), Gaps = 38/277 (13%)
Query: 623 LEEDWRRPLEEDFRRSPTEDFRQL---PEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPP 679
LE PL E+ P + L PEE PP E R P PPEE P
Sbjct: 426 LEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSP------PPEELPASPL 479
Query: 680 EEDFR--RPLQ-GEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPP 736
E RPL+ PPE+ PP E SP E+ SP E PP P
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE--ESPPSPALETP-- 535
Query: 737 EHFRRPPPEHFRRPPP--EHFRRPPPEHF-RRPPPEHFR-RPPPEH--FRRPPQEHFRRP 790
PPPE PP E PPPE PPPE R PPPE PP+E P
Sbjct: 536 ---LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 791 PQEH---FRRSREEDFRHPPDEDFRGPPDEDFR-HPPDED--FRSPQEEDFRCPSDEDFR 844
P E F E PP+E PP E R PP ED P EE P E R
Sbjct: 593 PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 845 QLP---EEDLREAPEEDPRLPDNFRPPGEDFRSPPDD 878
P L PEE P P PP E SPP +
Sbjct: 653 LSPLPVVSRLSPPPEESPLSP----PPEESPTSPPPE 685
Score = 81.3 bits (199), Expect = 4e-15
Identities = 123/408 (30%), Positives = 138/408 (33%), Gaps = 93/408 (22%)
Query: 550 PDRHPPEDFRHSSEDFRFPPEDFRHSPED----FRRPREEDFRRPSEEDFR--------- 596
P PPE R S PPE+ SP RP EE P E+
Sbjct: 457 PTSPPPEASRLSP-----PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511
Query: 597 -RPWEEDFRRPPEDDFRHPREED----------WRRPLEEDWRRPLEEDFRRSPTEDFRQ 645
P EE PPE+ P E P EE P E+ SP + +
Sbjct: 512 FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR 571
Query: 646 L------------PEEDFRQPPEEDLRWLP---EEDFRRPPEEDWRRPPEEDFRRPLQGE 690
L PEE PP E R P E PPEE PP E R
Sbjct: 572 LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS---- 627
Query: 691 WRRPPEDD-FRRPPEEDFRHSPEEDFRQSPQEHFRR---PPQEHFRRPPPEHF-RRPPPE 745
PPED PPEE P E R SP R PP+E PPPE PPPE
Sbjct: 628 --PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE 685
Query: 746 HFR-RPPPEHF-RRPPPEHF-RRPPPEHF----------------------RRPPPEHFR 780
R PPPE PPPE PPPE R P
Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
Query: 781 RPPQEHFR-RPPQEHFRRSREEDFRHPPDED--FRGPPDEDFRHPPDE-DFRSPQEEDFR 836
RP + H RP + H EE P E+ P+E P E SPQ E+
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
Query: 837 -CPSDED--FRQLPEED-LREAPEEDPRLPDNFRP-----PGEDFRSP 875
P E+ +PEE L PEE P + P P E SP
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSP 853
Score = 49.3 bits (116), Expect = 2e-05
Identities = 66/230 (28%), Positives = 84/230 (36%), Gaps = 30/230 (13%)
Query: 568 PPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRR--PPEDDFRHPREED--WRRPL 623
PPE+ SP P E P E P ED PPED P ED PL
Sbjct: 665 PPEESPLSPP----PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 624 EEDWRRPLEEDFRRSPTEDFRQL---PEEDFRQPPEEDLRWLPEED----FRRPPEEDWR 676
EE PL E+ + P + L PEE P E+ P+ + +P E
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780
Query: 677 RPPEEDFRRP-LQGEWRRPPEDDFRRPPEEDFRHS---PEEDFR--QSPQEHFRRPPQEH 730
PEE P +G P ++ P+ + H PEE Q + H +E
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 731 FRRPPPEHFRRPPPEHFRRPP----PEHFRRPPPEHFRRPPPEHFRRPPP 776
P PE P +PP PE +PP E + P PE PP
Sbjct: 841 CLSPRPEESHLSP--ELEKPPLSPRPE---KPPEEPGQCPAPEELPLFPP 885
>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 84.7 bits (208), Expect = 4e-16
Identities = 78/256 (30%), Positives = 117/256 (45%), Gaps = 36/256 (14%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGG----VHIIGGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G V G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQ-------KTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESV 113
I +E+F SS+AE++ K + M+R R G G + + + F E +
Sbjct: 173 KERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGF-ERM 231
Query: 114 KEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLK------AENPY----------- 156
+ A GYG D G + +G G G+ R R L +++ Y
Sbjct: 232 RRGAYGGGYGGY--DDYGGYNDGYGFGS--DRFGRDLNYCFSGMSDHRYGDGGSSFQSTT 287
Query: 157 ---LFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKC 213
+ +RGLPY E+D+ FFS L V DGR G+A V+FA+ DA +
Sbjct: 288 GHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAK 347
Query: 214 HRSFMGSRFIEVMQGS 229
++ M R++E+ S
Sbjct: 348 DKANMQHRYVELFLNS 363
Score = 60.5 bits (145), Expect = 8e-09
Identities = 54/237 (22%), Positives = 96/237 (40%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V+++ GLP+ ++ FF+ I +G G+ I G GEAF+ ++E+ + A+
Sbjct: 12 VVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + VE+F S+ EM ++ G P + G
Sbjct: 72 KKDRETMGHRYVEVFKSNSVEMDWVLK-----HTGPNSPDTANDG--------------- 111
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
++ LRGLP+ +++++ FFSG
Sbjct: 112 --------------------------------------FVRLRGLPFGCSKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ GR+ G+A V+FAS A LK H+ +G R+IE+ + S +
Sbjct: 134 LEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAE 190
Score = 60.5 bits (145), Expect = 8e-09
Identities = 80/365 (21%), Positives = 134/365 (36%), Gaps = 101/365 (27%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
+RGLP+ + D+V FFS + G+ F+ +GR +G+A V+ S + LK
Sbjct: 15 VRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALKKD 74
Query: 215 RSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPR 274
R MG R++EV F N+V+ VL+ + +SP ND
Sbjct: 75 RETMGHRYVEV----------FKSNSVEMDWVLKHTGPNSPDTA-NDG------------ 111
Query: 275 RTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKT 333
+V L+ L + ++ FF G ++ + + R T AFV F +
Sbjct: 112 ----------FVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFAS 161
Query: 334 LKDYNTALSLHKTVLQYRPV------------HIDPISRKQMLKFIARYEKK-------- 373
+ AL HK + +R + H DP + ++ Y++
Sbjct: 162 QEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNS 221
Query: 374 --RSGSLERDR------------------------------------PGHVSQKYSQEGN 395
R ER R G +Y G+
Sbjct: 222 IGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGS 281
Query: 396 SGQKL---CIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEE 452
S Q C+++R P+ T+ ++ FF+ L +++ G GEA V+F + E
Sbjct: 282 SFQSTTGHCVHMRGLPYRATENDIYNFFSP--LNPMRVHIEIGPDGRVTGEADVEFATHE 339
Query: 453 QAMKA 457
A+ A
Sbjct: 340 DAVAA 344
Score = 52.4 bits (124), Expect = 2e-06
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 24/186 (12%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTD--EQIRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V ++ L S ++ FF + + IRF+Y E R + AFV ++ ++
Sbjct: 10 GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRP-GHVSQKYSQEGNSGQ 398
AL + + +R V + +S S+E D H N G
Sbjct: 70 ALKKDRETMGHRYVEVF-----------------KSNSVEMDWVLKHTGPNSPDTANDG- 111
Query: 399 KLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAE 458
+ +R PF +K E+ +FF+ + + + L D +G GEA V+F S+E A KA
Sbjct: 112 --FVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 459 RLNRRR 464
+ ++ R
Sbjct: 170 KKHKER 175
Score = 45.8 bits (107), Expect = 2e-04
Identities = 23/72 (31%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEI 183
Score = 40.0 bits (92), Expect = 0.011
Identities = 30/81 (37%), Positives = 42/81 (51%), Gaps = 14/81 (17%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTI--------PDGGVHIIGGEIGEAFIIFATDEDARRA 56
+ + GLP+ A DI +FF+ L PDG V GEA + FAT EDA A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRV------TGEADVEFATHEDAVAA 344
Query: 57 ISRSGGFIKDSSVELFLSSKA 77
+++ ++ VELFL+S A
Sbjct: 345 MAKDKANMQHRYVELFLNSTA 365
Score = 36.6 bits (83), Expect = 0.12
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 18/112 (16%)
Query: 888 FGRPEGGKFDFGKHNMG-SFPEGRF----------MPDPKINCGSGRVTP-----IKIMN 931
+G GG D+G +N G F RF M D + G + +
Sbjct: 236 YGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRG 295
Query: 932 LPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
LP++A N+I +FF + P V I+ G TGEA V + +A+AA+
Sbjct: 296 LPYRATENDIYNFFS--PLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAM 345
Score = 36.2 bits (82), Expect = 0.16
Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQ--YNEQGLPTGEAIVAMINYNEAMAAIK 984
+K+ LP+ + +E++ FF +I + I+ Y +G P+GEA V + + E A+K
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 84.7 bits (208), Expect = 4e-16
Identities = 78/256 (30%), Positives = 117/256 (45%), Gaps = 36/256 (14%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGG----VHIIGGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G V G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQ-------KTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESV 113
I +E+F SS+AE++ K + M+R R G G + + + F E +
Sbjct: 173 KERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGF-ERM 231
Query: 114 KEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLK------AENPY----------- 156
+ A GYG D G + +G G G+ R R L +++ Y
Sbjct: 232 RRGAYGGGYGGY--DDYGGYNDGYGFGS--DRFGRDLNYCFSGMSDHRYGDGGSSFQSTT 287
Query: 157 ---LFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKC 213
+ +RGLPY E+D+ FFS L V DGR G+A V+FA+ DA +
Sbjct: 288 GHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAK 347
Query: 214 HRSFMGSRFIEVMQGS 229
++ M R++E+ S
Sbjct: 348 DKANMQHRYVELFLNS 363
Score = 60.5 bits (145), Expect = 8e-09
Identities = 54/237 (22%), Positives = 96/237 (40%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V+++ GLP+ ++ FF+ I +G G+ I G GEAF+ ++E+ + A+
Sbjct: 12 VVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + VE+F S+ EM ++ G P + G
Sbjct: 72 KKDRETMGHRYVEVFKSNSVEMDWVLK-----HTGPNSPDTANDG--------------- 111
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
++ LRGLP+ +++++ FFSG
Sbjct: 112 --------------------------------------FVRLRGLPFGCSKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ GR+ G+A V+FAS A LK H+ +G R+IE+ + S +
Sbjct: 134 LEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAE 190
Score = 60.5 bits (145), Expect = 8e-09
Identities = 80/365 (21%), Positives = 134/365 (36%), Gaps = 101/365 (27%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
+RGLP+ + D+V FFS + G+ F+ +GR +G+A V+ S + LK
Sbjct: 15 VRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALKKD 74
Query: 215 RSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPR 274
R MG R++EV F N+V+ VL+ + +SP ND
Sbjct: 75 RETMGHRYVEV----------FKSNSVEMDWVLKHTGPNSPDTA-NDG------------ 111
Query: 275 RTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKT 333
+V L+ L + ++ FF G ++ + + R T AFV F +
Sbjct: 112 ----------FVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFAS 161
Query: 334 LKDYNTALSLHKTVLQYRPV------------HIDPISRKQMLKFIARYEKK-------- 373
+ AL HK + +R + H DP + ++ Y++
Sbjct: 162 QEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNS 221
Query: 374 --RSGSLERDR------------------------------------PGHVSQKYSQEGN 395
R ER R G +Y G+
Sbjct: 222 IGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGS 281
Query: 396 SGQKL---CIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEE 452
S Q C+++R P+ T+ ++ FF+ L +++ G GEA V+F + E
Sbjct: 282 SFQSTTGHCVHMRGLPYRATENDIYNFFSP--LNPMRVHIEIGPDGRVTGEADVEFATHE 339
Query: 453 QAMKA 457
A+ A
Sbjct: 340 DAVAA 344
Score = 52.4 bits (124), Expect = 2e-06
Identities = 48/186 (25%), Positives = 81/186 (43%), Gaps = 24/186 (12%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTD--EQIRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V ++ L S ++ FF + + IRF+Y E R + AFV ++ ++
Sbjct: 10 GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRP-GHVSQKYSQEGNSGQ 398
AL + + +R V + +S S+E D H N G
Sbjct: 70 ALKKDRETMGHRYVEVF-----------------KSNSVEMDWVLKHTGPNSPDTANDG- 111
Query: 399 KLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAE 458
+ +R PF +K E+ +FF+ + + + L D +G GEA V+F S+E A KA
Sbjct: 112 --FVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 459 RLNRRR 464
+ ++ R
Sbjct: 170 KKHKER 175
Score = 45.8 bits (107), Expect = 2e-04
Identities = 23/72 (31%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEI 183
Score = 40.0 bits (92), Expect = 0.011
Identities = 30/81 (37%), Positives = 42/81 (51%), Gaps = 14/81 (17%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTI--------PDGGVHIIGGEIGEAFIIFATDEDARRA 56
+ + GLP+ A DI +FF+ L PDG V GEA + FAT EDA A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRV------TGEADVEFATHEDAVAA 344
Query: 57 ISRSGGFIKDSSVELFLSSKA 77
+++ ++ VELFL+S A
Sbjct: 345 MAKDKANMQHRYVELFLNSTA 365
Score = 36.6 bits (83), Expect = 0.12
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 18/112 (16%)
Query: 888 FGRPEGGKFDFGKHNMG-SFPEGRF----------MPDPKINCGSGRVTP-----IKIMN 931
+G GG D+G +N G F RF M D + G + +
Sbjct: 236 YGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRG 295
Query: 932 LPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
LP++A N+I +FF + P V I+ G TGEA V + +A+AA+
Sbjct: 296 LPYRATENDIYNFFS--PLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAM 345
Score = 36.2 bits (82), Expect = 0.16
Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQ--YNEQGLPTGEAIVAMINYNEAMAAIK 984
+K+ LP+ + +E++ FF +I + I+ Y +G P+GEA V + + E A+K
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
>gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo
sapiens]
Length = 449
Score = 82.8 bits (203), Expect = 1e-15
Identities = 76/256 (29%), Positives = 117/256 (45%), Gaps = 36/256 (14%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQ-------KTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESV 113
I +E+F SS+AE++ K + M+R R G G + + + F E +
Sbjct: 173 KERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGF-ERM 231
Query: 114 KEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLK------AENPY----------- 156
+ A GYG D + +G G G+ R R L +++ Y
Sbjct: 232 RRGAYGGGYGGY--DDYNGYNDGYGFGS--DRFGRDLNYCFSGMSDHRYGDGGSTFQSTT 287
Query: 157 ---LFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKC 213
+ +RGLPY E+D+ FFS L V DGR G+A V+FA+ DA +
Sbjct: 288 GHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSK 347
Query: 214 HRSFMGSRFIEVMQGS 229
++ M R++E+ S
Sbjct: 348 DKANMQHRYVELFLNS 363
Score = 63.5 bits (153), Expect = 9e-10
Identities = 87/407 (21%), Positives = 148/407 (36%), Gaps = 114/407 (28%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V+++ GLP+ +++ FF+ I +G G+ I G GEAF+ ++++ + A+
Sbjct: 12 VVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + VE+F S+ EM ++ G P + G
Sbjct: 72 KKDRETMGHRYVEVFKSNNVEMDWVLK-----HTGPNSPDTANDG--------------- 111
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
++ LRGLP+ +++++ FFSG
Sbjct: 112 --------------------------------------FVRLRGLPFGCSKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS------ 229
L + +G+ GR+ G+A V+FAS A LK H+ +G R+IE+ + S
Sbjct: 134 LEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRT 193
Query: 230 -----------------EQQWIEFGGNAVKEGDVLRRSEE---------HSPPRGINDRH 263
++ G N++ G R + G ND +
Sbjct: 194 HYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGY 253
Query: 264 --------------FRKRS-HSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTD 308
F S H + +S G VH++ L E D+ NFF +
Sbjct: 254 GFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLN 313
Query: 309 LTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHI 355
I + D T A V F T +D A+S K +Q+R V +
Sbjct: 314 PVRVHIE-IGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVEL 359
Score = 59.7 bits (143), Expect = 1e-08
Identities = 80/365 (21%), Positives = 134/365 (36%), Gaps = 101/365 (27%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
+RGLP+ + D+V+ FFS + G+ F+ +GR +G+A V+ S + LK
Sbjct: 15 VRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKD 74
Query: 215 RSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPR 274
R MG R++EV F N V+ VL+ + +SP ND
Sbjct: 75 RETMGHRYVEV----------FKSNNVEMDWVLKHTGPNSPDTA-NDG------------ 111
Query: 275 RTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKT 333
+V L+ L + ++ FF G ++ I + R T AFV F +
Sbjct: 112 ----------FVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFAS 161
Query: 334 LKDYNTALSLHKTVLQYRPV------------HIDPISRKQMLKFIARYEKK-------- 373
+ AL HK + +R + H DP + ++ Y++
Sbjct: 162 QEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNS 221
Query: 374 --RSGSLERDR------------------------------------PGHVSQKYSQEGN 395
R ER R G +Y G+
Sbjct: 222 IGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGS 281
Query: 396 SGQKL---CIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEE 452
+ Q C+++R P+ T+ ++ FF+ L +++ G GEA V+F + E
Sbjct: 282 TFQSTTGHCVHMRGLPYRATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFATHE 339
Query: 453 QAMKA 457
A+ A
Sbjct: 340 DAVAA 344
Score = 53.1 bits (126), Expect = 1e-06
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 24/186 (12%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTD--EQIRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V ++ L S +++ FF + + + IRF+Y E R + AFV ++ +
Sbjct: 10 GFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKL 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRP-GHVSQKYSQEGNSGQ 398
AL + + +R V + +S ++E D H N G
Sbjct: 70 ALKKDRETMGHRYVEVF-----------------KSNNVEMDWVLKHTGPNSPDTANDG- 111
Query: 399 KLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAE 458
+ +R PF +K E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 --FVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 459 RLNRRR 464
+ ++ R
Sbjct: 170 KKHKER 175
Score = 46.6 bits (109), Expect = 1e-04
Identities = 23/72 (31%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEI 183
Score = 41.2 bits (95), Expect = 0.005
Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 14/81 (17%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTI--------PDGGVHIIGGEIGEAFIIFATDEDARRA 56
+ + GLP+ A DI +FF+ L PDG V GEA + FAT EDA A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEDAVAA 344
Query: 57 ISRSGGFIKDSSVELFLSSKA 77
+S+ ++ VELFL+S A
Sbjct: 345 MSKDKANMQHRYVELFLNSTA 365
Score = 36.2 bits (82), Expect = 0.16
Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 397 GQKLCIYIRNFPFDVTKVEVQKFFADFLL--AEDDIYLLYDDKGVGLGEALVKFKSEEQA 454
G+ + +R P+ + EVQ+FF+D + I +Y +G GEA V+ +SE++
Sbjct: 8 GEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEV 67
Query: 455 MKAERLNR 462
A + +R
Sbjct: 68 KLALKKDR 75
Score = 35.0 bits (79), Expect = 0.35
Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQ--YNEQGLPTGEAIVAMINYNEAMAAIK 984
+K+ LP+ + +E+ FF +I + I+ Y +G P+GEA V + + +E A+K
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Score = 34.3 bits (77), Expect = 0.60
Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 18/112 (16%)
Query: 888 FGRPEGGKFDFGKHNMG-SFPEGRF----------MPDPKINCGSGRVTP-----IKIMN 931
+G GG D+ +N G F RF M D + G + +
Sbjct: 236 YGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRG 295
Query: 932 LPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
LP++A N+I +FF + P V I+ G TGEA V + +A+AA+
Sbjct: 296 LPYRATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAM 345
>gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Homo
sapiens]
Length = 318
Score = 82.8 bits (203), Expect = 1e-15
Identities = 77/328 (23%), Positives = 130/328 (39%), Gaps = 74/328 (22%)
Query: 169 DDVRVFFSGLCV----DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIE 224
+DV FFS + +G+ FL + DG+ GDA+++ S D L+ HR +MG R++E
Sbjct: 2 EDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVE 61
Query: 225 VMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGF 284
V + + + + D L +S + +ND
Sbjct: 62 VYEINNE-----------DVDALMKSLQVKSSPVVNDG---------------------- 88
Query: 285 YVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLH 344
V L+ L S +E+D+ +FF G ++ D Y+ +T A+V F+ + N AL H
Sbjct: 89 VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKH 148
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSL-------------------------- 378
+ + R + I P R ++ + Y+ K+ S
Sbjct: 149 REEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMT 208
Query: 379 ------ERDRPGHVSQKYSQE---GNSGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDD 429
E + P V +K + G + +++R PF ++ FFA L
Sbjct: 209 AFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAP--LKPVR 266
Query: 430 IYLLYDDKGVGLGEALVKFKSEEQAMKA 457
I + Y G GEA V F++ E A+ A
Sbjct: 267 ITMEYSSSGKATGEADVHFETHEDAVAA 294
Score = 57.0 bits (136), Expect = 9e-08
Identities = 53/220 (24%), Positives = 93/220 (42%), Gaps = 25/220 (11%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDG-RNNGDAIVKFASCVDASGGLKCHRSF 217
LRGLPY NE D+ FF+GL + + F+ + G R G+A V+F A+ L HR
Sbjct: 92 LRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREE 151
Query: 218 MGSRFIEVMQGSEQQ-WIEFGGNAVKEGDVLRRSEEHSPPRGINDRH-----------FR 265
+G+R+IE+ + G K+ ++ + P + + H F
Sbjct: 152 IGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMTAFE 211
Query: 266 KRSHSKSPRRTRSRSPLG---------FYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRF 316
+ P+ + P +VH++ L + +D+ NFF L +I
Sbjct: 212 SEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFF--APLKPVRITM 269
Query: 317 LYKDENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHI 355
Y + T A V F+T +D A+ ++ + +R + +
Sbjct: 270 EYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIEL 309
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/241 (24%), Positives = 96/241 (39%), Gaps = 31/241 (12%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPD-GGVHIIGG--EIGEAFIIFATDEDARRAISRS 60
V+RL GLP+ DI FF GL I D V G + GEA++ F E A +A+ +
Sbjct: 89 VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKH 148
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSL------------SN 108
I + +E+F S + E++ + + ++ + + +
Sbjct: 149 REEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQPMT 208
Query: 109 FIESVKEEASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNE 168
ES KE + + A F T + H ++ +RGLP+ N
Sbjct: 209 AFESEKEIELPKEVPEKLPEAADFGTTSSLH----------------FVHMRGLPFQANA 252
Query: 169 DDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQG 228
D+ FF+ L + G+ G+A V F + DA + RS + R+IE+
Sbjct: 253 QDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLN 312
Query: 229 S 229
S
Sbjct: 313 S 313
Score = 40.0 bits (92), Expect = 0.011
Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 4/63 (6%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+ + LPF+AN +I++FF + P ++++Y+ G TGEA V + +A+AA+ L
Sbjct: 241 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAM--L 296
Query: 987 NDR 989
DR
Sbjct: 297 KDR 299
Score = 30.8 bits (68), Expect = 6.7
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIV 971
+++ LP+ N +I+DFF G I+ + + Y + TGEA V
Sbjct: 90 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGR-RKTGEAYV 133
>gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens]
Length = 1180
Score = 77.4 bits (189), Expect = 6e-14
Identities = 88/334 (26%), Positives = 109/334 (32%), Gaps = 14/334 (4%)
Query: 553 HPPEDFRHSSED---FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPP 607
H PE + S + F P HSPE +R P FR P +R P FR P
Sbjct: 108 HSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPE 167
Query: 608 EDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDF 667
+R P +R P +R P E RSP PE PE + PE
Sbjct: 168 AAVYRSPEAAVFRSPEAAVYRSP-EAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAV 226
Query: 668 RRPPEEDWRRPPEED-FRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH-FRR 725
R PE PE + P + P F P F HSP SP +
Sbjct: 227 YRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVF-HSPGAAVYHSPGAAVYHS 285
Query: 726 PPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQE 785
P + P + P + P F P F P F P F P
Sbjct: 286 PGAAVYHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAA 345
Query: 786 HFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQ 845
+ P + FR P FR P +R P FRSP+ +R P +R
Sbjct: 346 VYHSPGAAVYHSPGAAVFRSPGAAVFRSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRS 405
Query: 846 LPEEDLREAPE----EDPRLPDNFRPPGEDFRSP 875
PE + PE P P F SP
Sbjct: 406 -PEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSP 438
Score = 74.3 bits (181), Expect = 5e-13
Identities = 65/234 (27%), Positives = 80/234 (34%), Gaps = 8/234 (3%)
Query: 644 RQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPP 703
R+ PE PE + PE PE PE + PE P
Sbjct: 43 RRAPEAAVFHSPEAAVYHSPEATVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAVYHSP 102
Query: 704 EEDFRHSPEEDFRQSPQEH-FRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEH 762
E HSPE SP+ F P F P +R P FR P +R P
Sbjct: 103 EAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEAAV 162
Query: 763 FRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHP 822
FR P +R P FR P +R P +R F P F P +R P
Sbjct: 163 FRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSP 222
Query: 823 PDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDNFRPPGED-FRSP 875
+RSP+ F CP + PE + +PE F PG F SP
Sbjct: 223 EAAVYRSPEAAVFHCPEAAVYHS-PEAAVYHSPEASV-----FHSPGAAVFHSP 270
Score = 72.4 bits (176), Expect = 2e-12
Identities = 82/294 (27%), Positives = 103/294 (35%), Gaps = 6/294 (2%)
Query: 565 FRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLE 624
FR P SPE P +R P +R +R +R +R P
Sbjct: 747 FRSPEAAVYRSPEA-AVPGAAVYRSPGAAVYRSRGAAVYRSRGAAVYRSRGAAVYRSPGA 805
Query: 625 EDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEED-F 683
+R FR SP + PE + PE + PE PE PE F
Sbjct: 806 AVYRSREAAVFR-SPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVF 864
Query: 684 RRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH-FRRPPQEHFRRPPPEHFRRP 742
P + P F P F HSP SP +R P +R P +R P
Sbjct: 865 HSPEAAVYHSPEAAVFHSPGAAVF-HSPGAAVFHSPGAAVYRSPGAAVYRSPGAAVYRSP 923
Query: 743 PPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREED 802
+R P +R P FR P FR P +R P FR P +R
Sbjct: 924 GAAVYRSPGAAVYRSPGAAVFRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAV 983
Query: 803 FRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPE 856
FR P +R P FR P +RSP FR P FR PE + +PE
Sbjct: 984 FRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVFR-CPEAAVYHSPE 1036
Score = 69.3 bits (168), Expect = 2e-11
Identities = 72/306 (23%), Positives = 100/306 (32%), Gaps = 8/306 (2%)
Query: 547 FRQPDR---HPPEDFRHSSED---FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRP 598
+R P+ H PE + S + + P HSP F P + P F P
Sbjct: 403 YRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSP 462
Query: 599 WEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEED 658
+ P + P + P + P F + F P
Sbjct: 463 GAAVYHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAV 522
Query: 659 LRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQS 718
R FR P +R P FR P +R P FR P +R +R
Sbjct: 523 YRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSP 582
Query: 719 PQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEH 778
+R P +R P +R P +R P +R P FR P +R P
Sbjct: 583 GAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAV 642
Query: 779 FRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCP 838
FR P +R P +R +R P FR P +R P +RSP +R P
Sbjct: 643 FRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSP 702
Query: 839 SDEDFR 844
+R
Sbjct: 703 GAAVYR 708
Score = 68.2 bits (165), Expect = 4e-11
Identities = 83/333 (24%), Positives = 104/333 (31%), Gaps = 12/333 (3%)
Query: 553 HPPED-FRHSSED--FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPP 607
H PE HS E + P HSPE F P + P F P F P
Sbjct: 76 HSPEAAVFHSPEAAVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPE 135
Query: 608 EDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDF 667
+R P +R P +R P FR SP + PE + PE + PE
Sbjct: 136 AAVYRSPEAAVFRSPEAAVYRSPEAAVFR-SPEAAVYRSPEAAVFRSPEAAVYRSPEAAV 194
Query: 668 RRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH-FRRP 726
R PE PE + R PE R PE H PE SP+ + P
Sbjct: 195 YRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSP 254
Query: 727 PQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEH 786
F P F P + P + P + P + P + P
Sbjct: 255 EASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAV 314
Query: 787 FRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQL 846
F P F F P F P + P + SP FR P FR
Sbjct: 315 FHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFRSPGAAVFRS- 373
Query: 847 PEEDLREAPE----EDPRLPDNFRPPGEDFRSP 875
P + +PE P P +RSP
Sbjct: 374 PGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSP 406
Score = 67.8 bits (164), Expect = 5e-11
Identities = 73/313 (23%), Positives = 100/313 (31%), Gaps = 2/313 (0%)
Query: 565 FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRP 622
F P HSP + P F P + P F P + P + P
Sbjct: 459 FHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSP 518
Query: 623 LEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEED 682
+R P FR +R FR P R FR P +R P
Sbjct: 519 GAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAV 578
Query: 683 FRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRP 742
+R P +R P +R P +R +R +R P FR P +R P
Sbjct: 579 YRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSP 638
Query: 743 PPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREED 802
FR P +R P +R P +R P FR P +R P +R
Sbjct: 639 GAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAV 698
Query: 803 FRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLP 862
+R P +R +R +RS +R P +R R R P
Sbjct: 699 YRSPGAAVYRSRGAAVYRSRGAAVYRSRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSP 758
Query: 863 DNFRPPGEDFRSP 875
+ P +RSP
Sbjct: 759 EAAVPGAAVYRSP 771
Score = 64.7 bits (156), Expect = 4e-10
Identities = 64/267 (23%), Positives = 86/267 (32%), Gaps = 2/267 (0%)
Query: 565 FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRP 622
F P HSP F P + P + P F P + P + P
Sbjct: 443 FHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSP 502
Query: 623 LEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEED 682
+ P F +R FR P R FR P +R P
Sbjct: 503 GAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAV 562
Query: 683 FRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRP 742
FR P +R P +R P +R +R +R P +R P +R P
Sbjct: 563 FRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSP 622
Query: 743 PPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREED 802
FR P +R P FR P +R P +R P +R P FR
Sbjct: 623 GAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAV 682
Query: 803 FRHPPDEDFRGPPDEDFRHPPDEDFRS 829
+R P +R P +R P +RS
Sbjct: 683 YRSPGAAVYRSPGAAVYRSPGAAVYRS 709
Score = 61.2 bits (147), Expect = 5e-09
Identities = 67/292 (22%), Positives = 86/292 (29%), Gaps = 6/292 (2%)
Query: 552 RHPPEDFRHSSED--FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPP 607
R P HS E + P HSPE + P F P + P + P
Sbjct: 44 RAPEAAVFHSPEAAVYHSPEATVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAVYHSPE 103
Query: 608 EDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDF 667
F P + P + P F +R FR P R F
Sbjct: 104 AAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVF 163
Query: 668 RRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH-FRRP 726
R P +R P FR P + R PE R PE HSPE P+ +R P
Sbjct: 164 RSPEAAVYRSPEAAVFRSP-EAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSP 222
Query: 727 PQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEH 786
+R P F P + P + P F P F P + P
Sbjct: 223 EAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAV 282
Query: 787 FRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCP 838
+ P + + P + P F P F SP F P
Sbjct: 283 YHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSP 334
Score = 61.2 bits (147), Expect = 5e-09
Identities = 75/315 (23%), Positives = 95/315 (30%), Gaps = 29/315 (9%)
Query: 553 HPPEDFRHSSED---FRFPPEDFRHSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPP 607
H PE + S + FR P SPE FR P +R P FR P +R P
Sbjct: 132 HSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPE 191
Query: 608 EDDFRHPREEDWRRPLEEDWRRPLEEDFR-------RSPTEDFRQLPEEDFRQPPEEDLR 660
+R P + P + P +R RSP PE PE +
Sbjct: 192 AAVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVY 251
Query: 661 WLPEED---------FRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRP-------PE 704
PE F P + P + P + P + P P
Sbjct: 252 HSPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPG 311
Query: 705 EDFRHSPEEDFRQSPQEH-FRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHF 763
HSP SP F P F P + P + P FR P F
Sbjct: 312 AAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFRSPGAAVF 371
Query: 764 RRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPP 823
R P +R P FR P +R P +R F P + P + P
Sbjct: 372 RSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPE 431
Query: 824 DEDFRSPQEEDFRCP 838
F SP F P
Sbjct: 432 ASVFHSPGAAVFHSP 446
Score = 58.5 bits (140), Expect = 3e-08
Identities = 76/308 (24%), Positives = 92/308 (29%), Gaps = 7/308 (2%)
Query: 574 HSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPL 631
HSP + P F P F P F P F P + P + P
Sbjct: 300 HSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHSPG 359
Query: 632 EEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEW 691
FR FR +R P R PE R PE R PE +
Sbjct: 360 AAVFRSPGAAVFRSPGAAVYRSPEAAVFR-SPEAAVYRSPEAAVYRSPEAAVFHCPEAAV 418
Query: 692 RRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH-FRRPPQEHFRRPPPEHFRRPPPEHFRRP 750
PE PE HSP SP + P F P + P + P
Sbjct: 419 YHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSP 478
Query: 751 PPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDED 810
F P + P F P + P F P +R FR P
Sbjct: 479 GAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAAV 538
Query: 811 FRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDN--FRPP 868
+R P FR P +RSP FR P +R R R P +R P
Sbjct: 539 YRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSP 598
Query: 869 GED-FRSP 875
G +RSP
Sbjct: 599 GAAVYRSP 606
Score = 58.2 bits (139), Expect = 4e-08
Identities = 76/308 (24%), Positives = 92/308 (29%), Gaps = 7/308 (2%)
Query: 574 HSPED--FRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPL 631
HSP + P + P F P F P F P + P + P
Sbjct: 292 HSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPG 351
Query: 632 EEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEW 691
+ FR FR P R PE R PE R PE R +
Sbjct: 352 AAVYHSPGAAVFRSPGAAVFRSPGAAVYR-SPEAAVFRSPEAAVYRSPEAAVYRSPEAAV 410
Query: 692 RRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH-FRRPPQEHFRRPPPEHFRRPPPEHFRRP 750
PE PE HSPE SP F P + P F P + P
Sbjct: 411 FHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSP 470
Query: 751 PPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDED 810
+ P F P + P F P + P F +R P
Sbjct: 471 GAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYRSPGAAV 530
Query: 811 FRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDN--FRPP 868
FR P +R P FRSP +R P FR R R P +R P
Sbjct: 531 FRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSP 590
Query: 869 GED-FRSP 875
G +RSP
Sbjct: 591 GAAVYRSP 598
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 77.0 bits (188), Expect = 8e-14
Identities = 124/493 (25%), Positives = 192/493 (38%), Gaps = 47/493 (9%)
Query: 447 KFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQI--QEFGVNFSVMSSEKMQARSQSRER 504
KF EEQ ++ ER R+F E LL+ E Q+ QE F E+ Q R Q R+R
Sbjct: 1447 KFLEEEQQLRQER--HRKFREEEQLLQEREEQQLHRQERDRKFL---EEEQQLRRQERDR 1501
Query: 505 GDHSHLFDSKDPPIYSVGAFENFRHQ------LEDLRQLDNFKHPQRDFRQPDR--HPPE 556
S++P + + Q L++ +QL + Q+ + DR E
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 557 DFRHSSEDFRFPPED----FRHSPEDFRRPREEDFRRPSEEDFRRP-------WEEDFRR 605
R E+ + ++ FR + RR +E E+ RR E D +
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 606 PPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEE-DFRQPPEEDLRWLPE 664
++ REE E D R+ LEE+ + E +QL + D + EE L E
Sbjct: 1622 REDEQLLQEREEQQLHRQERD-RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 665 EDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQ-SPQEHF 723
E R E D + EE R + E + E+ R E + + EE RQ + QE
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 724 RRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPP 783
RR QE +R+ E RP E + E R+ FR E R+ E R
Sbjct: 1741 RR--QERYRKILEEEQLRPEREEQQLRRQERDRK-----FRE--EEQLRQEREEQQLRSQ 1791
Query: 784 QEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDF 843
+ + +E R+ REE P D + +E+ +++ R QE D + ++E F
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF 1851
Query: 844 -----RQLPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDFRSHRPFVNF----GRPEGG 894
+ E++L + E+ R + E R + + HR G+ G
Sbjct: 1852 ATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Query: 895 KFDFGKHNMGSFP 907
+ G H S P
Sbjct: 1912 LLEPGTHQFASVP 1924
Score = 66.2 bits (160), Expect = 1e-10
Identities = 109/456 (23%), Positives = 182/456 (39%), Gaps = 63/456 (13%)
Query: 449 KSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHS 508
K + + + ER +FL E L+ AQ + + E+ +++ Q R++
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Query: 509 HLFDSKDPPIYSVGAFENFRHQLEDLRQL--DNFKHPQRDFRQPDRHPPEDFRHSSEDFR 566
L + + +++ A + QL +QL + + QR+ R+ R ++ ++ E+
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 567 FPPEDFRHSPEDFRRPREE-----------------------DFRRPSEEDFRRPWEEDF 603
E+ E +R R+E + RR E + + EE+
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 604 RRPPEDDFRHPREEDWRRPLEEDWRRP-----------LEEDFRRSPTEDFRQLPEEDFR 652
++ E R RE+ R+ E +R+ EE +R E RQ EE+
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 653 QPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPE 712
Q EE L E + RR E + + EE+ ++ + R PE +R +E R E
Sbjct: 1057 QQEEEQLLG-EERETRRRQELERQYRKEEELQQEEEQLLREEPE---KRRRQERERQCRE 1112
Query: 713 EDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFR 772
E+ Q +E R +E RR E R+ E + E R PE RR E R
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELE--RQYREEEEVQQEEEQLLREEPEKRRRQELE--R 1168
Query: 773 RPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRS--- 829
+ E + +E R QE R+ RE +R +E R + +R DED RS
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQYRE-EEELQRQKRKQRYR---DEDQRSDLK 1224
Query: 830 ----PQEED--------FRCPSDEDFRQLPEEDLRE 853
P++E+ + +E FRQL + LR+
Sbjct: 1225 WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Score = 64.7 bits (156), Expect = 4e-10
Identities = 77/338 (22%), Positives = 135/338 (39%), Gaps = 4/338 (1%)
Query: 525 ENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPRE 584
E R Q D + + + Q QP R D + E+ R + + E+ R R+
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 585 EDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFR 644
E R+ +E+ + +E ++ +D R REE+ + +E R+ EE+ + E R
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 645 QLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPE 704
+ EE+ + E ++ EE + EE E D R+ L+ E + ++ R+ E
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD-RKFLEEEQQLRRQERDRKFRE 1505
Query: 705 EDFR-HSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHF 763
++ R PE F + Q+ R+ Q F + + R+ + R+ FR
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 764 RRPPPEHFRRPPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPP 823
R + R+ FR Q+ R+ + F ++ R + R D FR
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE-- 1623
Query: 824 DEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRL 861
DE +EE + D + L EE E + +L
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Score = 63.9 bits (154), Expect = 7e-10
Identities = 106/450 (23%), Positives = 165/450 (36%), Gaps = 44/450 (9%)
Query: 449 KSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHS 508
+ EEQ ++ ER RRR E+ + E ++Q+ EK + + R+ +
Sbjct: 1118 QEEEQLLREEREKRRR---QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 509 HLFDSKDPPIYSVGAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFP 568
L ++ + E + + E RQ + QR R+ R+ ED R S +++
Sbjct: 1175 ELQQEEEQLLRE----EQEKRRQERERQYREEEELQRQKRK-QRYRDEDQR-SDLKWQWE 1228
Query: 569 PEDFR-----------HSPEDFRRPREEDFR-RPSEEDFR--------RPWEEDFRRPPE 608
PE E FR+ + R R S++D + R E++ RR +
Sbjct: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ 1288
Query: 609 DDFRHPREEDWRRPLEEDWRR-----PLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLP 663
D P EE R +++ +R E+ R E+ R+ E D + EE L
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Query: 664 EEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFR-QSPQEH 722
EE R E D R+ EE+ R QG E RR E E+ R Q ++
Sbjct: 1349 EEQPLRRQERD-RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 723 FRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRP 782
R+ FR + R+ FR + RR E + R+ FR
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFRE-EEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 783 PQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFR------HPPDEDFRSPQEEDFR 836
Q R Q+ R+ R+ F + R D FR P+ F +++ R
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 837 CPSDEDFRQLPEEDLREAPEEDPRLPDNFR 866
F Q E+ LR R D R
Sbjct: 1527 QQRQRKFLQ-EEQQLRRQERGQQRRQDRDR 1555
Score = 63.2 bits (152), Expect = 1e-09
Identities = 95/431 (22%), Positives = 158/431 (36%), Gaps = 59/431 (13%)
Query: 447 KFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGD 506
K + E+Q ++ ER +RR T+ R E Q+ + E+ R Q R+R
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFR--EEEQL--------LQEREEQPLRRQERDRKF 1362
Query: 507 HSHLFDSKDPPIYSVGAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFR 566
E RHQ + + L+ + +R R+ F + R
Sbjct: 1363 RE----------------EELRHQEQGRKFLEEEQRLRRQERE------RKFLKEEQQLR 1400
Query: 567 FPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEED 626
+ + R+ R+ FR ++ R+ + FR E++ + R+E R+ LEE+
Sbjct: 1401 CQERE-----QQLRQDRDRKFREEEQQLSRQERDRKFR---EEEQQVRRQERERKFLEEE 1452
Query: 627 WRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWR--------RP 678
+ E + E Q EE E D ++L EE R E D + +
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 679 PEEDFRRPLQGEWRRPPEDDF--------RRPPEEDFRHSPEEDFRQSPQEHFRRPPQEH 730
PE F Q R+ + F R+ + R + FR+ Q R Q+
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
Query: 731 FRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRP 790
R+ FR + R+ F + R+ + R+ FR Q R
Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQERE 1632
Query: 791 PQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEED 850
Q+ R+ R+ F + R ++ RH D FR +EE +E + E D
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR--EEEQLLQEGEEQQLRRQERD 1690
Query: 851 LREAPEEDPRL 861
R+ EE+ +L
Sbjct: 1691 -RKFREEEQQL 1700
Score = 58.9 bits (141), Expect = 2e-08
Identities = 83/342 (24%), Positives = 140/342 (40%), Gaps = 35/342 (10%)
Query: 535 RQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEED 594
RQ + + P R+ R+ E R E P E+ + RR RE++ + EE+
Sbjct: 781 RQRLSARPPLREQRERQLRAEE--RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 595 F--RRPWEEDFRRPPE---DDFRHPREEDWRRPLEEDWRRPLEEDFRR-------SPTED 642
RR + + + +D R ++ RR ++ WR LEE+ +R P
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 643 FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRP 702
+ E+ Q EE+L+ E + RR E++ + EE ++ + R E + RR
Sbjct: 897 EQLRKEQQLLQEEEEELQ-REEREKRRRQEQERQYREEEQLQQEEEQLLRE--EREKRRR 953
Query: 703 PEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEH 762
E + ++ ++ +Q ++ P++ R+ + +R E + E R E
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE---EEELQQEEEQLLREEREK 1010
Query: 763 FRRPPPEHFRRPPPEHFRRPPQ----EHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDED 818
RR E R E + Q E +R QE R+ REE+ +E G E
Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERET 1070
Query: 819 FRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPR 860
R R E +R +E+ +Q E+ LRE PE+ R
Sbjct: 1071 RR-------RQELERQYR--KEEELQQEEEQLLREEPEKRRR 1103
Score = 57.0 bits (136), Expect = 9e-08
Identities = 115/446 (25%), Positives = 176/446 (39%), Gaps = 77/446 (17%)
Query: 453 QAMKAERLNRRRFLGTEVLLRLISEAQIQE-FGVNFSVMSSEKMQARSQSRERGDHSHLF 511
QA + R R G E LL+ + + Q F + E Q R Q R+ +
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE--- 147
Query: 512 DSKDPPIYSVGAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPED 571
+ E + E L Q D + + +RQ + R + E+ +
Sbjct: 148 ---------LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKG 198
Query: 572 FRHSPEDFRRPREEDFRRPSEEDFRRPWEEDF---RRPPEDD-FRHPREEDWRRP---LE 624
H E+F P EE RR + RR E+ RR +D F+ E++WR+ L
Sbjct: 199 --HETEEF--PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR 254
Query: 625 EDWRRPLEEDFRRS-----PTEDFRQLPEEDFRQPPEED----LRWLPEEDFRRPPEEDW 675
++ + EE+ +R E R+L ++ R+ +E+ R E+ RR EE+
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 676 RRPPEE----DFRRPLQGEWRRPPEDDFRRPPEE----DFRHSPEEDFRQS----PQEHF 723
R EE RR Q E R E RR EE R EE+ R+ QE
Sbjct: 315 REQQEERREQQERREQQEERR---EQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 724 RRPPQ----EHFRRPP----PEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPP 775
RR Q + RR + RR + RR + RR + RR + RR
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRR--EQQLRR--EQQLRR--EQQLRR--EQQLRR-- 421
Query: 776 PEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDE--DFRGPPDEDFRHPPD---EDFRSP 830
+ RR +E R Q+H + RE+ + +E D+ +E RH + + +
Sbjct: 422 EQQLRREQEE--ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 831 QEEDFRCPSDEDFRQLPEEDLREAPE 856
QEE+ R E + +L EE+ RE E
Sbjct: 480 QEEERR----ERWLKLEEEERREQQE 501
Score = 53.5 bits (127), Expect = 1e-06
Identities = 112/493 (22%), Positives = 190/493 (38%), Gaps = 93/493 (18%)
Query: 241 VKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDL 300
++E LRR E R DR FR+ + R + S ++ ++E+ +
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR-----QERDRKFRLEEQKV 1588
Query: 301 RNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYR---PVHIDP 357
R EQ R +DE + R + ++ + + +LQ R +H
Sbjct: 1589 RR--------QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 358 ISRKQMLK--FIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYIRNFPFDVTKVE 415
RK + + + R E+++ +RDR ++ QEG Q+L R+ F + +
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE-QQLRRQERDRKFREEEQQ 1699
Query: 416 VQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQ-AMKAERLNRRRFLGTEVLLRL 474
+++ E + L +++ + E KF+ EEQ + E+ RR E ++
Sbjct: 1700 LRR-------QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR---QERYRKI 1749
Query: 475 ISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHLFDSKDPPIYSVGAFENFRHQLEDL 534
+ E Q++ E+ Q R Q R+R FR + E L
Sbjct: 1750 LEEEQLRP--------EREEQQLRRQERDR---------------------KFREE-EQL 1779
Query: 535 RQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEED 594
RQ +R+ +Q R D +F E E R+ REE RP + D
Sbjct: 1780 RQ-------EREEQQ--------LRSQESDRKFREE------EQLRQEREEQQLRPQQRD 1818
Query: 595 FRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQP 654
+ WEE+ + E + R +E D + EE + +E RR E +++ E+ RQ
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF--ATQEKSRREEQELWQE-EEQKRRQE 1875
Query: 655 PEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPL---QGEWRRPPEDDFRRPPEEDFRHSP 711
E LR EE RR +E+ R + + G P F P R SP
Sbjct: 1876 RERKLR---EEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVP---VRSSP 1929
Query: 712 EEDFRQSPQEHFR 724
++ Q + +R
Sbjct: 1930 LYEYIQEQRSQYR 1942
Score = 49.3 bits (116), Expect = 2e-05
Identities = 64/279 (22%), Positives = 107/279 (38%), Gaps = 27/279 (9%)
Query: 532 EDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPS 591
+ LR+ + Q+ R+ + R + R E+ RH + + RE+ +R
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQ-LRREQEEERHEQKHEQERREQRLKREQ 451
Query: 592 EEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDF 651
EE RR W + REE+ R +E ++ L+ D E + +L EE+
Sbjct: 452 EE--RRDWLK-------------REEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
Query: 652 RQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSP 711
R+ E + L E R + R+ EE ++ L+ E + E + RR E+ +
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR--EQLLKREE 554
Query: 712 EEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHF-RRPPPEHFRRPPPE- 769
E+ Q +E + QE R + + +R E +R E R E
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Query: 770 ----HFRRPPPEHFRRP---PQEHFRRPPQEHFRRSREE 801
+R PE RR E Q+ RR ++E
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Score = 48.5 bits (114), Expect = 3e-05
Identities = 72/303 (23%), Positives = 112/303 (36%), Gaps = 35/303 (11%)
Query: 449 KSEEQAMKAERLNRR------------RFLGTEVLLRLISEAQIQ--------EFGVNFS 488
+ EEQ+ K ERL +R R E R E Q+Q EF
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 489 VMSSEKMQARSQSRERGDHSHLFDSKDPPIYSVGAFENFRHQLEDLRQLDNFKHPQRDFR 548
+ E ++ R + RE + ++ + +R + LR+ + + R
Sbjct: 210 LRRRELLELRRKGREEKQQQRR--ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 549 QPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPE 608
Q + E+ E E + R RE+ RR EE+ R EE R +
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE---RREQ 324
Query: 609 DDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFR--QLPEEDFRQPPEEDLRWLPEED 666
+ R +EE + L + E+ RR E+ R QL E + E+ LR E+
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR--REQQ 382
Query: 667 FRRPP----EEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEH 722
RR E+ RR + + L+ E + E RR E+ R EE+ + E
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR--EQQLRREQEEERHEQKHEQ 440
Query: 723 FRR 725
RR
Sbjct: 441 ERR 443
Score = 47.8 bits (112), Expect = 5e-05
Identities = 96/433 (22%), Positives = 166/433 (38%), Gaps = 51/433 (11%)
Query: 452 EQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHLF 511
EQ ++ E+ RR + L R E ++Q+ + + E+ + R Q +R + L
Sbjct: 504 EQQLRREQEERRE----QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 512 DSKDPPIYSVGAFENFRHQL---EDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFP 568
+ E R QL E+ R+ K Q + R R E+ ++ R
Sbjct: 560 QERREQRLKREQEER-RDQLLKREEERRQQRLKREQEE-RLEQRLKREEVERLEQEERRE 617
Query: 569 PEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWR 628
R PE+ RR + + E++ RR ++ RR ++ RE+ +R EE+
Sbjct: 618 QRLKREEPEEERR---QQLLKSEEQEERR--QQQLRREQQER----REQRLKREEEEE-- 666
Query: 629 RPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFR---- 684
LE+ +R E+ R E++ + +E R E R P+ W+ E D R
Sbjct: 667 -RLEQRLKREHEEERR---EQELAEEEQEQAR---ERIKSRIPKWQWQLESEADARQSKV 719
Query: 685 ----RPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRR-------PPQEHFRR 733
R +G+ RR +++ RR E + + EE + QE +R +E R
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
Query: 734 PPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPQEHFRRPPQE 793
RPP R R E P E + + R + F ++
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 794 HFRRSR------EEDFRHPPDEDFRGPP---DEDFRHPPDEDFRSPQEEDFRCPSDEDFR 844
RR R EED E R D+ +R +E+ + + + P+ ++
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 845 QLPEEDLREAPEE 857
+ ++ L+E EE
Sbjct: 900 RKEQQLLQEEEEE 912
>gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b
[Homo sapiens]
Length = 331
Score = 77.0 bits (188), Expect = 8e-14
Identities = 72/239 (30%), Positives = 105/239 (43%), Gaps = 16/239 (6%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF GL I G+ + G GEAF+ FA+ E A A+ +
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRT---------DRVGRGRPGSGTSGVDSLSNFIE 111
I +E+F SS++E++ + R DR GR G +G S F +
Sbjct: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDD 137
Query: 112 SVKEEASNSGYGSSINQDAGFHTNGT-GHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDD 170
+N GYG+ D G GHG ++ +RGLP+ E+D
Sbjct: 138 --YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATEND 195
Query: 171 VRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
+ FFS L V DGR G+A V+F + DA + ++ M R+IE+ S
Sbjct: 196 IANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNS 254
Score = 55.5 bits (132), Expect = 3e-07
Identities = 58/242 (23%), Positives = 94/242 (38%), Gaps = 36/242 (14%)
Query: 149 PLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNNGDAIVKFASCVD 206
P A + + LRGLP+ +++++ FF GL + +G+ + GR+ G+A V+FAS
Sbjct: 10 PNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEI 69
Query: 207 ASGGLKCHRSFMGSRFIEVMQGSEQQWIEF-------------------GGNAVKEGDVL 247
A L H+ +G R+IE+ + S + F GG G
Sbjct: 70 AENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGR 129
Query: 248 RRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGF--------------YVHLKNLSL 293
G N+ + R R G+ +VH++ L
Sbjct: 130 GSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPF 189
Query: 294 SIDERDLRNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPV 353
E D+ NFF + I + D T A V F T +D A+S K +Q+R +
Sbjct: 190 RATENDIANFFSPLNPIRVHID-IGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYI 248
Query: 354 HI 355
+
Sbjct: 249 EL 250
Score = 43.9 bits (102), Expect = 8e-04
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 78 KER-IGHRYIEI 88
Score = 38.9 bits (89), Expect = 0.024
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 402 IYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLN 461
+ +R PF +K E+ +FF + + I L D +G GEA V+F S+E A A +
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 462 RRRFLGTEVLLRLISEAQIQEF 483
+ R + + S ++I+ F
Sbjct: 78 KERIGHRYIEIFRSSRSEIKGF 99
Score = 37.7 bits (86), Expect = 0.054
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI-KD 985
+ + LPF+A N+I +FF + P V I G TGEA V + + +A+AA+ KD
Sbjct: 182 VHMRGLPFRATENDIANFFS--PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
Query: 986 LND 988
N+
Sbjct: 240 KNN 242
Score = 34.7 bits (78), Expect = 0.46
Identities = 47/220 (21%), Positives = 82/220 (37%), Gaps = 50/220 (22%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLH 344
V L+ L + ++ FF+G ++ I + R T AFV F + + AL H
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 345 KTVLQYRPVHIDPISRKQMLKFI---ARYEKKRSGSLER--------------------D 381
K + +R + I SR ++ F R +R G +R D
Sbjct: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDD 137
Query: 382 RPGHVSQKYSQEG-----NSGQKL-------------------CIYIRNFPFDVTKVEVQ 417
G+ + Y +G G+ + +++R PF T+ ++
Sbjct: 138 YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIA 197
Query: 418 KFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA 457
FF+ L +++ G GEA V+F + E A+ A
Sbjct: 198 NFFSP--LNPIRVHIDIGADGRATGEADVEFVTHEDAVAA 235
>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 26/251 (10%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQK----TIEMKRTDRVGR-GRPGSGTSGVDSLSNF-IESVK 114
I +E+F SS+ E++ ++ R G RPG+ + + +E ++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMR 232
Query: 115 EEASNSGYG-----SSINQDAGFHTNGTGHG-----------NLRPRKTRPLKAENPYLF 158
A ++GYG S ++ GF T+ G + +
Sbjct: 233 PGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVH 292
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFM 218
+RGLPY E+D+ FFS L V DGR G+A V+FA+ +A + R+ M
Sbjct: 293 MRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANM 352
Query: 219 GSRFIEVMQGS 229
R+IE+ S
Sbjct: 353 QHRYIELFLNS 363
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/237 (24%), Positives = 103/237 (43%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V++L GLP+ D+++F + TI DG GVH I G + GEAF+ +++D + A+
Sbjct: 12 VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + +E+F S + EM ++ SG + DS
Sbjct: 72 KKDRESMGHRYIEVFKSHRTEMDWVLKH------------SGPNSADS------------ 107
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
A + ++ LRGLP+ ++++ FFSG
Sbjct: 108 ----------------------------------ANDGFVRLRGLPFGCTKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ +G+ G+A V+FAS A L H+ +G R+IEV + S+++
Sbjct: 134 LEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEE 190
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 110/432 (25%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
LRGLP+ + +DV+ F S + GV F+ +GR +G+A V+ S D LK
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 215 RSFMGSRFIEVMQG--SEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKS 272
R MG R+IEV + +E W+ +HS P +
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWV----------------LKHSGPNSAD------------ 106
Query: 273 PRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMF 331
S +V L+ L + ++ FF G ++ I E + T AFV F
Sbjct: 107 -------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQF 159
Query: 332 KTLKDYNTALSLHKTVLQYRPVHIDPISRKQM-------LKFIA-----RYEKK------ 373
+ + AL HK + +R + + S++++ LKF++ Y++
Sbjct: 160 ASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRY 219
Query: 374 ----RSGSLERDRPGHVSQKY-SQEGNSGQK----------------------------- 399
+ LER RPG S Y E SG
Sbjct: 220 IGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS 279
Query: 400 ---------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
C+++R P+ T+ ++ FF+ L +++ G GEA V+F +
Sbjct: 280 EFTVQSTTGHCVHMRGLPYKATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFAT 337
Query: 451 EEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHL 510
E+A+ A +R + L L S G + SS+ MQ S + +S L
Sbjct: 338 HEEAVAAMSKDRANMQHRYIELFLNSTT-----GASNGAYSSQVMQGMGVSAAQATYSGL 392
Query: 511 FDSKDPPIYSVG 522
Y G
Sbjct: 393 ESQSVSGCYGAG 404
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 27/189 (14%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ--IRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V L+ L S D++NF + D + F+Y E R + AFV + D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQK 399
AL + + +R + + R +M + K SG D N G
Sbjct: 70 ALKKDRESMGHRYIEVFKSHRTEM-----DWVLKHSGPNSAD-----------SANDG-- 111
Query: 400 LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA-- 457
+ +R PF TK E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 -FVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALG 170
Query: 458 ---ERLNRR 463
ER+ R
Sbjct: 171 KHKERIGHR 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF EI+ FF G I+P+ +++ + +G TGEA V + A A+
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEV 183
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
+ + LP+KA N+I +FF + P V I+ G TGEA V + EA+AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345
>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 26/251 (10%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQK----TIEMKRTDRVGR-GRPGSGTSGVDSLSNF-IESVK 114
I +E+F SS+ E++ ++ R G RPG+ + + +E ++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMR 232
Query: 115 EEASNSGYG-----SSINQDAGFHTNGTGHG-----------NLRPRKTRPLKAENPYLF 158
A ++GYG S ++ GF T+ G + +
Sbjct: 233 PGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVH 292
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFM 218
+RGLPY E+D+ FFS L V DGR G+A V+FA+ +A + R+ M
Sbjct: 293 MRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANM 352
Query: 219 GSRFIEVMQGS 229
R+IE+ S
Sbjct: 353 QHRYIELFLNS 363
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/237 (24%), Positives = 103/237 (43%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V++L GLP+ D+++F + TI DG GVH I G + GEAF+ +++D + A+
Sbjct: 12 VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + +E+F S + EM ++ SG + DS
Sbjct: 72 KKDRESMGHRYIEVFKSHRTEMDWVLKH------------SGPNSADS------------ 107
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
A + ++ LRGLP+ ++++ FFSG
Sbjct: 108 ----------------------------------ANDGFVRLRGLPFGCTKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ +G+ G+A V+FAS A L H+ +G R+IEV + S+++
Sbjct: 134 LEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEE 190
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 110/432 (25%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
LRGLP+ + +DV+ F S + GV F+ +GR +G+A V+ S D LK
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 215 RSFMGSRFIEVMQG--SEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKS 272
R MG R+IEV + +E W+ +HS P +
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWV----------------LKHSGPNSAD------------ 106
Query: 273 PRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMF 331
S +V L+ L + ++ FF G ++ I E + T AFV F
Sbjct: 107 -------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQF 159
Query: 332 KTLKDYNTALSLHKTVLQYRPVHIDPISRKQM-------LKFIA-----RYEKK------ 373
+ + AL HK + +R + + S++++ LKF++ Y++
Sbjct: 160 ASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRY 219
Query: 374 ----RSGSLERDRPGHVSQKY-SQEGNSGQK----------------------------- 399
+ LER RPG S Y E SG
Sbjct: 220 IGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS 279
Query: 400 ---------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
C+++R P+ T+ ++ FF+ L +++ G GEA V+F +
Sbjct: 280 EFTVQSTTGHCVHMRGLPYKATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFAT 337
Query: 451 EEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHL 510
E+A+ A +R + L L S G + SS+ MQ S + +S L
Sbjct: 338 HEEAVAAMSKDRANMQHRYIELFLNSTT-----GASNGAYSSQVMQGMGVSAAQATYSGL 392
Query: 511 FDSKDPPIYSVG 522
Y G
Sbjct: 393 ESQSVSGCYGAG 404
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 27/189 (14%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ--IRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V L+ L S D++NF + D + F+Y E R + AFV + D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQK 399
AL + + +R + + R +M + K SG D N G
Sbjct: 70 ALKKDRESMGHRYIEVFKSHRTEM-----DWVLKHSGPNSAD-----------SANDG-- 111
Query: 400 LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA-- 457
+ +R PF TK E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 -FVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALG 170
Query: 458 ---ERLNRR 463
ER+ R
Sbjct: 171 KHKERIGHR 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF EI+ FF G I+P+ +++ + +G TGEA V + A A+
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEV 183
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
+ + LP+KA N+I +FF + P V I+ G TGEA V + EA+AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345
>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 26/251 (10%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQK----TIEMKRTDRVGR-GRPGSGTSGVDSLSNF-IESVK 114
I +E+F SS+ E++ ++ R G RPG+ + + +E ++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMR 232
Query: 115 EEASNSGYG-----SSINQDAGFHTNGTGHG-----------NLRPRKTRPLKAENPYLF 158
A ++GYG S ++ GF T+ G + +
Sbjct: 233 PGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVH 292
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFM 218
+RGLPY E+D+ FFS L V DGR G+A V+FA+ +A + R+ M
Sbjct: 293 MRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANM 352
Query: 219 GSRFIEVMQGS 229
R+IE+ S
Sbjct: 353 QHRYIELFLNS 363
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/237 (24%), Positives = 103/237 (43%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V++L GLP+ D+++F + TI DG GVH I G + GEAF+ +++D + A+
Sbjct: 12 VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + +E+F S + EM ++ SG + DS
Sbjct: 72 KKDRESMGHRYIEVFKSHRTEMDWVLKH------------SGPNSADS------------ 107
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
A + ++ LRGLP+ ++++ FFSG
Sbjct: 108 ----------------------------------ANDGFVRLRGLPFGCTKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ +G+ G+A V+FAS A L H+ +G R+IEV + S+++
Sbjct: 134 LEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEE 190
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 110/432 (25%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
LRGLP+ + +DV+ F S + GV F+ +GR +G+A V+ S D LK
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 215 RSFMGSRFIEVMQG--SEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKS 272
R MG R+IEV + +E W+ +HS P +
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWV----------------LKHSGPNSAD------------ 106
Query: 273 PRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMF 331
S +V L+ L + ++ FF G ++ I E + T AFV F
Sbjct: 107 -------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQF 159
Query: 332 KTLKDYNTALSLHKTVLQYRPVHIDPISRKQM-------LKFIA-----RYEKK------ 373
+ + AL HK + +R + + S++++ LKF++ Y++
Sbjct: 160 ASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRY 219
Query: 374 ----RSGSLERDRPGHVSQKY-SQEGNSGQK----------------------------- 399
+ LER RPG S Y E SG
Sbjct: 220 IGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS 279
Query: 400 ---------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
C+++R P+ T+ ++ FF+ L +++ G GEA V+F +
Sbjct: 280 EFTVQSTTGHCVHMRGLPYKATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFAT 337
Query: 451 EEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHL 510
E+A+ A +R + L L S G + SS+ MQ S + +S L
Sbjct: 338 HEEAVAAMSKDRANMQHRYIELFLNSTT-----GASNGAYSSQVMQGMGVSAAQATYSGL 392
Query: 511 FDSKDPPIYSVG 522
Y G
Sbjct: 393 ESQSVSGCYGAG 404
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 27/189 (14%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ--IRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V L+ L S D++NF + D + F+Y E R + AFV + D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQK 399
AL + + +R + + R +M + K SG D N G
Sbjct: 70 ALKKDRESMGHRYIEVFKSHRTEM-----DWVLKHSGPNSAD-----------SANDG-- 111
Query: 400 LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA-- 457
+ +R PF TK E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 -FVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALG 170
Query: 458 ---ERLNRR 463
ER+ R
Sbjct: 171 KHKERIGHR 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF EI+ FF G I+P+ +++ + +G TGEA V + A A+
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEV 183
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
+ + LP+KA N+I +FF + P V I+ G TGEA V + EA+AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345
>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 26/251 (10%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQK----TIEMKRTDRVGR-GRPGSGTSGVDSLSNF-IESVK 114
I +E+F SS+ E++ ++ R G RPG+ + + +E ++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMR 232
Query: 115 EEASNSGYG-----SSINQDAGFHTNGTGHG-----------NLRPRKTRPLKAENPYLF 158
A ++GYG S ++ GF T+ G + +
Sbjct: 233 PGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVH 292
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFM 218
+RGLPY E+D+ FFS L V DGR G+A V+FA+ +A + R+ M
Sbjct: 293 MRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANM 352
Query: 219 GSRFIEVMQGS 229
R+IE+ S
Sbjct: 353 QHRYIELFLNS 363
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/237 (24%), Positives = 103/237 (43%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V++L GLP+ D+++F + TI DG GVH I G + GEAF+ +++D + A+
Sbjct: 12 VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + +E+F S + EM ++ SG + DS
Sbjct: 72 KKDRESMGHRYIEVFKSHRTEMDWVLKH------------SGPNSADS------------ 107
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
A + ++ LRGLP+ ++++ FFSG
Sbjct: 108 ----------------------------------ANDGFVRLRGLPFGCTKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ +G+ G+A V+FAS A L H+ +G R+IEV + S+++
Sbjct: 134 LEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEE 190
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 110/432 (25%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
LRGLP+ + +DV+ F S + GV F+ +GR +G+A V+ S D LK
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 215 RSFMGSRFIEVMQG--SEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKS 272
R MG R+IEV + +E W+ +HS P +
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWV----------------LKHSGPNSAD------------ 106
Query: 273 PRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMF 331
S +V L+ L + ++ FF G ++ I E + T AFV F
Sbjct: 107 -------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQF 159
Query: 332 KTLKDYNTALSLHKTVLQYRPVHIDPISRKQM-------LKFIA-----RYEKK------ 373
+ + AL HK + +R + + S++++ LKF++ Y++
Sbjct: 160 ASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRY 219
Query: 374 ----RSGSLERDRPGHVSQKY-SQEGNSGQK----------------------------- 399
+ LER RPG S Y E SG
Sbjct: 220 IGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS 279
Query: 400 ---------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
C+++R P+ T+ ++ FF+ L +++ G GEA V+F +
Sbjct: 280 EFTVQSTTGHCVHMRGLPYKATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFAT 337
Query: 451 EEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHL 510
E+A+ A +R + L L S G + SS+ MQ S + +S L
Sbjct: 338 HEEAVAAMSKDRANMQHRYIELFLNSTT-----GASNGAYSSQVMQGMGVSAAQATYSGL 392
Query: 511 FDSKDPPIYSVG 522
Y G
Sbjct: 393 ESQSVSGCYGAG 404
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 27/189 (14%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ--IRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V L+ L S D++NF + D + F+Y E R + AFV + D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQK 399
AL + + +R + + R +M + K SG D N G
Sbjct: 70 ALKKDRESMGHRYIEVFKSHRTEM-----DWVLKHSGPNSAD-----------SANDG-- 111
Query: 400 LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA-- 457
+ +R PF TK E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 -FVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALG 170
Query: 458 ---ERLNRR 463
ER+ R
Sbjct: 171 KHKERIGHR 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF EI+ FF G I+P+ +++ + +G TGEA V + A A+
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEV 183
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
+ + LP+KA N+I +FF + P V I+ G TGEA V + EA+AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345
>gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 26/251 (10%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQK----TIEMKRTDRVGR-GRPGSGTSGVDSLSNF-IESVK 114
I +E+F SS+ E++ ++ R G RPG+ + + +E ++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMR 232
Query: 115 EEASNSGYG-----SSINQDAGFHTNGTGHG-----------NLRPRKTRPLKAENPYLF 158
A ++GYG S ++ GF T+ G + +
Sbjct: 233 PGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVH 292
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFM 218
+RGLPY E+D+ FFS L V DGR G+A V+FA+ +A + R+ M
Sbjct: 293 MRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANM 352
Query: 219 GSRFIEVMQGS 229
R+IE+ S
Sbjct: 353 QHRYIELFLNS 363
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/237 (24%), Positives = 103/237 (43%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V++L GLP+ D+++F + TI DG GVH I G + GEAF+ +++D + A+
Sbjct: 12 VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + +E+F S + EM ++ SG + DS
Sbjct: 72 KKDRESMGHRYIEVFKSHRTEMDWVLKH------------SGPNSADS------------ 107
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
A + ++ LRGLP+ ++++ FFSG
Sbjct: 108 ----------------------------------ANDGFVRLRGLPFGCTKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ +G+ G+A V+FAS A L H+ +G R+IEV + S+++
Sbjct: 134 LEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEE 190
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 110/432 (25%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
LRGLP+ + +DV+ F S + GV F+ +GR +G+A V+ S D LK
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 215 RSFMGSRFIEVMQG--SEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKS 272
R MG R+IEV + +E W+ +HS P +
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWV----------------LKHSGPNSAD------------ 106
Query: 273 PRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMF 331
S +V L+ L + ++ FF G ++ I E + T AFV F
Sbjct: 107 -------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQF 159
Query: 332 KTLKDYNTALSLHKTVLQYRPVHIDPISRKQM-------LKFIA-----RYEKK------ 373
+ + AL HK + +R + + S++++ LKF++ Y++
Sbjct: 160 ASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRY 219
Query: 374 ----RSGSLERDRPGHVSQKY-SQEGNSGQK----------------------------- 399
+ LER RPG S Y E SG
Sbjct: 220 IGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS 279
Query: 400 ---------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
C+++R P+ T+ ++ FF+ L +++ G GEA V+F +
Sbjct: 280 EFTVQSTTGHCVHMRGLPYKATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFAT 337
Query: 451 EEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHL 510
E+A+ A +R + L L S G + SS+ MQ S + +S L
Sbjct: 338 HEEAVAAMSKDRANMQHRYIELFLNSTT-----GASNGAYSSQVMQGMGVSAAQATYSGL 392
Query: 511 FDSKDPPIYSVG 522
Y G
Sbjct: 393 ESQSVSGCYGAG 404
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 27/189 (14%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ--IRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V L+ L S D++NF + D + F+Y E R + AFV + D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQK 399
AL + + +R + + R +M + K SG D N G
Sbjct: 70 ALKKDRESMGHRYIEVFKSHRTEM-----DWVLKHSGPNSAD-----------SANDG-- 111
Query: 400 LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA-- 457
+ +R PF TK E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 -FVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALG 170
Query: 458 ---ERLNRR 463
ER+ R
Sbjct: 171 KHKERIGHR 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF EI+ FF G I+P+ +++ + +G TGEA V + A A+
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEV 183
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
+ + LP+KA N+I +FF + P V I+ G TGEA V + EA+AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345
>gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 26/251 (10%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF+GL I G+ + G GEAF+ FA+ E A +A+ +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 61 GGFIKDSSVELFLSSKAEMQK----TIEMKRTDRVGR-GRPGSGTSGVDSLSNF-IESVK 114
I +E+F SS+ E++ ++ R G RPG+ + + +E ++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMR 232
Query: 115 EEASNSGYG-----SSINQDAGFHTNGTGHG-----------NLRPRKTRPLKAENPYLF 158
A ++GYG S ++ GF T+ G + +
Sbjct: 233 PGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVH 292
Query: 159 LRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFM 218
+RGLPY E+D+ FFS L V DGR G+A V+FA+ +A + R+ M
Sbjct: 293 MRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANM 352
Query: 219 GSRFIEVMQGS 229
R+IE+ S
Sbjct: 353 QHRYIELFLNS 363
Score = 70.5 bits (171), Expect = 8e-12
Identities = 59/237 (24%), Positives = 103/237 (43%), Gaps = 66/237 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII----GGEIGEAFIIFATDEDARRAI 57
V++L GLP+ D+++F + TI DG GVH I G + GEAF+ +++D + A+
Sbjct: 12 VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71
Query: 58 SRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEA 117
+ + +E+F S + EM ++ SG + DS
Sbjct: 72 KKDRESMGHRYIEVFKSHRTEMDWVLKH------------SGPNSADS------------ 107
Query: 118 SNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSG 177
A + ++ LRGLP+ ++++ FFSG
Sbjct: 108 ----------------------------------ANDGFVRLRGLPFGCTKEEIVQFFSG 133
Query: 178 LCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQ 232
L + +G+ +G+ G+A V+FAS A L H+ +G R+IEV + S+++
Sbjct: 134 LEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEE 190
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 110/432 (25%)
Query: 159 LRGLPYLVNEDDVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCH 214
LRGLP+ + +DV+ F S + GV F+ +GR +G+A V+ S D LK
Sbjct: 15 LRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKD 74
Query: 215 RSFMGSRFIEVMQG--SEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKS 272
R MG R+IEV + +E W+ +HS P +
Sbjct: 75 RESMGHRYIEVFKSHRTEMDWV----------------LKHSGPNSAD------------ 106
Query: 273 PRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMF 331
S +V L+ L + ++ FF G ++ I E + T AFV F
Sbjct: 107 -------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQF 159
Query: 332 KTLKDYNTALSLHKTVLQYRPVHIDPISRKQM-------LKFIA-----RYEKK------ 373
+ + AL HK + +R + + S++++ LKF++ Y++
Sbjct: 160 ASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRY 219
Query: 374 ----RSGSLERDRPGHVSQKY-SQEGNSGQK----------------------------- 399
+ LER RPG S Y E SG
Sbjct: 220 IGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDS 279
Query: 400 ---------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450
C+++R P+ T+ ++ FF+ L +++ G GEA V+F +
Sbjct: 280 EFTVQSTTGHCVHMRGLPYKATENDIYNFFSP--LNPVRVHIEIGPDGRVTGEADVEFAT 337
Query: 451 EEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVNFSVMSSEKMQARSQSRERGDHSHL 510
E+A+ A +R + L L S G + SS+ MQ S + +S L
Sbjct: 338 HEEAVAAMSKDRANMQHRYIELFLNSTT-----GASNGAYSSQVMQGMGVSAAQATYSGL 392
Query: 511 FDSKDPPIYSVG 522
Y G
Sbjct: 393 ESQSVSGCYGAG 404
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 27/189 (14%)
Query: 283 GFYVHLKNLSLSIDERDLRNFFRGTDLTDEQ--IRFLYKDENR-TRYAFVMFKTLKDYNT 339
GF V L+ L S D++NF + D + F+Y E R + AFV + D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 340 ALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQK 399
AL + + +R + + R +M + K SG D N G
Sbjct: 70 ALKKDRESMGHRYIEVFKSHRTEM-----DWVLKHSGPNSAD-----------SANDG-- 111
Query: 400 LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA-- 457
+ +R PF TK E+ +FF+ + + I L D +G GEA V+F S+E A KA
Sbjct: 112 -FVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALG 170
Query: 458 ---ERLNRR 463
ER+ R
Sbjct: 171 KHKERIGHR 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF EI+ FF G I+P+ +++ + +G TGEA V + A A+
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 173 KER-IGHRYIEV 183
Score = 36.2 bits (82), Expect = 0.16
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983
+ + LP+KA N+I +FF + P V I+ G TGEA V + EA+AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345
>gi|45935393 RNA binding motif protein 35B [Homo sapiens]
Length = 717
Score = 73.6 bits (179), Expect = 9e-13
Identities = 73/266 (27%), Positives = 110/266 (41%), Gaps = 59/266 (22%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGV-------HIIGGEIGEAFIIFATDEDARR 55
V++RL GLPF AGP D+ F GG H G G+AF +FA +E A+
Sbjct: 348 VILRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQA 407
Query: 56 AISRSGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKE 115
A+ R G + +ELF S+ AE+Q+ + R SG + +L+ + +
Sbjct: 408 ALRRHKGMLGKRYIELFRSTAAEVQQVL----------NRYASGPL-LPTLTAPLLPIPF 456
Query: 116 EASNSGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFF 175
+ GTG +R LRGLPY +D+ F
Sbjct: 457 PLA----------------PGTGRDCVR---------------LRGLPYTATIEDILSFL 485
Query: 176 SGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDA-SGGLKCHRSFMGSRFIEVMQGSE 230
D GV + + GR +GDA ++ S A + +CH+ M R++EV+ S
Sbjct: 486 GEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQRCHKKVMKERYVEVVPCST 545
Query: 231 QQWIEFGGNAVKEGDVLRRSEEHSPP 256
++ + V G L RS PP
Sbjct: 546 EEM-----SRVLMGGTLGRSGMSPPP 566
Score = 65.1 bits (157), Expect = 3e-10
Identities = 66/307 (21%), Positives = 125/307 (40%), Gaps = 43/307 (14%)
Query: 160 RGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSF 217
RGLP+ ++ DV FF GL V GV + GR NG+A+++F L+ H+
Sbjct: 252 RGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHH 311
Query: 218 MGSRFIEVMQGSEQQWIEF-GGNAVKEGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRT 276
MG R+IEV + + +++++ GG +++ L R ++
Sbjct: 312 MGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQ------------------------ 347
Query: 277 RSRSPLGFYVHLKNLSLSIDERDLRNFFRG----TDLTDEQIRFLYKDENRTRYAFVMFK 332
+ L+ L S D+ F T T+ + + D T AF +F
Sbjct: 348 -------VILRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFA 400
Query: 333 TLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQ 392
+ AL HK +L R + + + ++ + + RY SG L +
Sbjct: 401 CEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRY---ASGPLLPTLTAPLLPIPFP 457
Query: 393 EGNSGQKLCIYIRNFPFDVTKVEVQKFFADFL--LAEDDIYLLYDDKGVGLGEALVKFKS 450
+ C+ +R P+ T ++ F + + ++++ + +G G+A ++ S
Sbjct: 458 LAPGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTS 517
Query: 451 EEQAMKA 457
E+A+ A
Sbjct: 518 AERALAA 524
Score = 40.4 bits (93), Expect = 0.008
Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 920 GSGRVTPIKIMNLPFKANVNEILDFFH--GYRIIPDSVSIQYNEQGLPTGEAIVAMINYN 977
G+GR +++ LP+ A + +IL F I P V + N+QG P+G+A + M +
Sbjct: 461 GTGRDC-VRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAE 519
Query: 978 EAMAAIKDLNDRPVGPRKVKL 998
A+AA + + + + R V++
Sbjct: 520 RALAAAQRCHKKVMKERYVEV 540
Score = 38.5 bits (88), Expect = 0.032
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISR 59
V+R GLP+ + D+ FF GL + GGV + G GEA I F E A+ R
Sbjct: 248 VVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQR 307
Query: 60 SGGFIKDSSVELFLSSKAEMQK 81
+ +E++ ++ E K
Sbjct: 308 HKHHMGVRYIEVYKATGEEFVK 329
Score = 33.5 bits (75), Expect = 1.0
Identities = 14/60 (23%), Positives = 32/60 (53%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
T ++ LP++++ ++ FF G + V++ N QG GEA++ ++ + A++
Sbjct: 247 TVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQ 306
Score = 32.7 bits (73), Expect = 1.8
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 361 KQMLKFIARYEKKRSGSLERDRPGHVSQKY-----SQEGNSGQKLCIYIRNFPFDVTKVE 415
K M+ I K+ S L +P + QKY S+ + + R P+ + +
Sbjct: 204 KTMVAVILHLLKEPSSQLF-SKPEVIKQKYETGPCSKADVVDSETVVRARGLPWQSSDQD 262
Query: 416 VQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQ 453
V +FF +A + L + +G GEAL++F EQ
Sbjct: 263 VARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQ 300
>gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a
[Homo sapiens]
Length = 346
Score = 73.6 bits (179), Expect = 9e-13
Identities = 71/254 (27%), Positives = 111/254 (43%), Gaps = 31/254 (12%)
Query: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
+RL GLPF +I FF GL I G+ + G GEAF+ FA+ E A A+ +
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRT---------DRVGRGRPGSGTSGVDSLSNFIE 111
I +E+F SS++E++ + R DR GR G +G S+ + +
Sbjct: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
Query: 112 SVKEEASNSGYGSSINQDAGFHTNGTGHGNL--RPRKTRPLKAE--------------NP 155
+ + GYG + G++ G G+ R R R +
Sbjct: 138 R-GGDGYDGGYG-GFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH 195
Query: 156 YLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHR 215
++ +RGLP+ E+D+ FFS L V DGR G+A V+F + DA + +
Sbjct: 196 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 255
Query: 216 SFMGSRFIEVMQGS 229
+ M R+IE+ S
Sbjct: 256 NNMQHRYIELFLNS 269
Score = 53.1 bits (126), Expect = 1e-06
Identities = 61/257 (23%), Positives = 99/257 (38%), Gaps = 51/257 (19%)
Query: 149 PLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNNGDAIVKFASCVD 206
P A + + LRGLP+ +++++ FF GL + +G+ + GR+ G+A V+FAS
Sbjct: 10 PNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEI 69
Query: 207 ASGGLKCHRSFMGSRFIEVMQGSEQQWIEF-------------------GGNAVKEG--- 244
A L H+ +G R+IE+ + S + F GG G
Sbjct: 70 AENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGR 129
Query: 245 ----DVLRRSEE--------HSPPRGINDRHFRKRSHSKSPRRTRSRSPLGF-------- 284
D +RR + G N+ + R R G+
Sbjct: 130 GSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASS 189
Query: 285 ------YVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTRYAFVMFKTLKDYN 338
+VH++ L E D+ NFF + I + D T A V F T +D
Sbjct: 190 GFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHID-IGADGRATGEADVEFVTHEDAV 248
Query: 339 TALSLHKTVLQYRPVHI 355
A+S K +Q+R + +
Sbjct: 249 AAMSKDKNNMQHRYIEL 265
Score = 43.9 bits (102), Expect = 8e-04
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 987 NDRPVGPRKVKL 998
+R +G R +++
Sbjct: 78 KER-IGHRYIEI 88
Score = 38.9 bits (89), Expect = 0.024
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 402 IYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLN 461
+ +R PF +K E+ +FF + + I L D +G GEA V+F S+E A A +
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 462 RRRFLGTEVLLRLISEAQIQEF 483
+ R + + S ++I+ F
Sbjct: 78 KERIGHRYIEIFRSSRSEIKGF 99
Score = 37.7 bits (86), Expect = 0.054
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
Query: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI-KD 985
+ + LPF+A N+I +FF + P V I G TGEA V + + +A+AA+ KD
Sbjct: 197 VHMRGLPFRATENDIANFFS--PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
Query: 986 LND 988
N+
Sbjct: 255 KNN 257
Score = 33.1 bits (74), Expect = 1.3
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLH 344
V L+ L + ++ FF+G ++ I + R T AFV F + + AL H
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPG 384
K + +R + I SR ++ F Y+ R L RPG
Sbjct: 78 KERIGHRYIEIFRSSRSEIKGF---YDPPR--RLLGQRPG 112
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 69.3 bits (168), Expect = 2e-11
Identities = 80/347 (23%), Positives = 154/347 (44%), Gaps = 53/347 (15%)
Query: 554 PPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSE----EDFRRPWEEDFRRPPED 609
P E+ ++ + P ++ SP + + P +E+ + P+E E + P +E+ + PPE
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE- 563
Query: 610 DFRHPREEDWRRPLE----EDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEE 665
+ P +E+ + P E E + P +E+ +SP E + PE+ + P +E+ +
Sbjct: 564 -AKSPEKEEAKSPAEVKSPEKAKSPAKEE-AKSPAE--AKSPEK-AKSPVKEEAK--SPA 616
Query: 666 DFRRPPEEDWRRPPE----EDFRRPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQE 721
+ + P +E+ + P E E + P + E + P + + PE++ SPE+ +SP +
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK---AKSPEKEEAKSPEK--AKSPVK 671
Query: 722 HFRRPPQE-----HFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRP----PPEHFR 772
+ P++ PE + P E + PE + P E + P P
Sbjct: 672 AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK--SPEKAKSPVKEEAKSPEKAKSPVKEE 729
Query: 773 RPPPEHFRRPPQEHFRRPPQ-EHFRRSREEDFRHPPDEDFRGPPDEDFRHPPD---EDFR 828
PE + P +E + P + + +++ D + P + + P E+ R P D E +
Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP---EAKTPAKEEARSPADKFPEKAK 786
Query: 829 SPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDNFRPPGEDFRSP 875
SP +E+ + P E + +ED + P+ P E+ +SP
Sbjct: 787 SPVKEEVKSP----------EKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Score = 67.8 bits (164), Expect = 5e-11
Identities = 84/334 (25%), Positives = 148/334 (44%), Gaps = 56/334 (16%)
Query: 577 EDFRRPREEDFRRPS--EEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEED 634
E+ + +EE+ + EE+ EE+ + PP ++ P E++ + P++E+ + P E
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASP-EKEAKSPVKEEAKSPAE-- 529
Query: 635 FRRSPTEDFRQLP-----EEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPE----EDFRR 685
+SP ++ + P E + P +E+ + PE + P +E+ + P E E +
Sbjct: 530 -AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA--KSPEKEEAKSPAEVKSPEKAKS 586
Query: 686 PLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRP----PPEHFRR 741
P + E + P E + PE+ SP ++ +SP E + P +E + P PE +
Sbjct: 587 PAKEEAKSPAE---AKSPEK--AKSPVKEEAKSPAE-AKSPVKEEAKSPAEVKSPEKAKS 640
Query: 742 PPPEHFRRP----PPEHFRRPPPEHFRRP------PPEHFRRP------PPEHFRRPPQE 785
P E + P PE PE + P PE + P PE + P +E
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE 700
Query: 786 HFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQ 845
+ P E + +E+ + P E + P E+ + P E +SP +E+ + P + +
Sbjct: 701 EAKSP--EKAKSPVKEEAKSP--EKAKSPVKEEAKTP--EKAKSPVKEEAKSP---EKAK 751
Query: 846 LPEEDLREAPEEDPRLPDNFRPPGEDFRSPPDDF 879
PE +A D + P+ P E+ RSP D F
Sbjct: 752 SPE----KAKTLDVKSPEAKTPAKEEARSPADKF 781
Score = 41.2 bits (95), Expect = 0.005
Identities = 47/233 (20%), Positives = 103/233 (44%), Gaps = 28/233 (12%)
Query: 532 EDLRQLDNFKHP-QRDFRQPDR--HPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFR 588
E+ + + K P + + + P++ P ++ + E + P ++ SPE + P +
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 589 RPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPE 648
+ + P +E+ R P D F E + P++E+ + P + +SP ++ + PE
Sbjct: 760 DVKSPEAKTPAKEE-ARSPADKF----PEKAKSPVKEEVKSP---EKAKSPLKEDAKAPE 811
Query: 649 EDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDFR 708
++ P +E+++ P ++ +P E + PP+ + E + P P E+ +
Sbjct: 812 KEI--PKKEEVK-SPVKEEEKPQEVKVKEPPK-------KAEEEKAP----ATPKTEEKK 857
Query: 709 HSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPE 761
S +E ++P++ +P E + P E + E + + + P PE
Sbjct: 858 DSKKE---EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
>gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens]
Length = 604
Score = 67.8 bits (164), Expect = 5e-11
Identities = 83/399 (20%), Positives = 163/399 (40%), Gaps = 58/399 (14%)
Query: 77 AEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSINQDAGFHTNG 136
A M + + +++ V R G S V+ + N I ++ E N + + F +
Sbjct: 159 ATMTEYLNFEKSSSVSR----YGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGT 214
Query: 137 TGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNN 194
L +N + RGLP+ ++ D+ FF GL + G + GR N
Sbjct: 215 CSKMELID--------DNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRN 266
Query: 195 GDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHS 254
G+A+V+F S L+ H+ MG+R+IEV + + + +++ G E E
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQ- 325
Query: 255 PPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFF-RGTDLT--D 311
V ++ L + ++ FF + +T
Sbjct: 326 -----------------------------VIVRMRGLPFTATAEEVVAFFGQHCPITGGK 356
Query: 312 EQIRFL-YKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARY 370
E I F+ Y D T AFV+F + AL HK +L R + + + ++ + + R+
Sbjct: 357 EGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRF 416
Query: 371 EKKRSGSLERDRPGHV---SQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFL--L 425
+ + P + Q++ N + CI +R P+ T ++ F +F +
Sbjct: 417 SS--APLIPLPTPPIIPVLPQQFVPPTN--VRDCIRLRGLPYAATIEDILDFLGEFATDI 472
Query: 426 AEDDIYLLYDDKGVGLGEALVKFKSEEQA-MKAERLNRR 463
++++ + +G G+A ++ KS ++A M A++ +++
Sbjct: 473 RTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKK 511
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/236 (24%), Positives = 91/236 (38%), Gaps = 66/236 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISR 59
V+R GLP+ + DI FF GL I GG + G GEA + F ++E A+ R
Sbjct: 226 VVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQR 285
Query: 60 SGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASN 119
+ +E++ ++ + K
Sbjct: 286 HKHHMGTRYIEVYKATGEDFLKIA------------------------------------ 309
Query: 120 SGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-LRGLPYLVNEDDVRVFFSGL 178
G + N+ A F L EN + +RGLP+ ++V FF
Sbjct: 310 ---GGTSNEVAQF-----------------LSKENQVIVRMRGLPFTATAEEVVAFFGQH 349
Query: 179 C-----VDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
C +G++F+ + DGR GDA V FA A L+ H+ +G R+IE+ + +
Sbjct: 350 CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRST 405
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/272 (26%), Positives = 102/272 (37%), Gaps = 69/272 (25%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVH--IIGGEIGEAFIIFATDEDARRAISRS 60
V++R+ GLPF A ++ FF G H I GG+ G I+F T D R
Sbjct: 326 VIVRMRGLPFTATAEEVVAFF--------GQHCPITGGKEG---ILFVTYPDGRPT---G 371
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
F+ L + E + K D +G+ +IE + A+
Sbjct: 372 DAFV--------LFACEEYAQNALRKHKDLLGK--------------RYIELFRSTAAE- 408
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-----------LRGLPYLVNED 169
+ Q N L P T P+ P F LRGLPY +
Sbjct: 409 -----VQQVL----NRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIE 459
Query: 170 DVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDA-SGGLKCHRSFMGSRFIE 224
D+ F D GV + +H GR +GDA ++ S A KCH+ M R++E
Sbjct: 460 DILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVE 519
Query: 225 VMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPP 256
V Q S ++ N V G L R+ PP
Sbjct: 520 VFQCSAEEM-----NFVLMGGTLNRNGLSPPP 546
Score = 39.7 bits (91), Expect = 0.014
Identities = 46/208 (22%), Positives = 80/208 (38%), Gaps = 22/208 (10%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YAFVMFKTLKDYNTALSLH 344
V + L ++D+ FF+G ++ + R A V F + + + AL H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYI 404
K + R + + + + LK G S + +Q + ++ + +
Sbjct: 287 KHHMGTRYIEVYKATGEDFLKIA----------------GGTSNEVAQFLSKENQVIVRM 330
Query: 405 RNFPFDVTKVEVQKFFADFLL----AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERL 460
R PF T EV FF E +++ Y D G G+A V F EE A A R
Sbjct: 331 RGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPD-GRPTGDAFVLFACEEYAQNALRK 389
Query: 461 NRRRFLGTEVLLRLISEAQIQEFGVNFS 488
++ + L + A++Q+ FS
Sbjct: 390 HKDLLGKRYIELFRSTAAEVQQVLNRFS 417
Score = 37.4 bits (85), Expect = 0.071
Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYR--IIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
I++ LP+ A + +ILDF + I V + N QG P+G+A + M + + A A +
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 985 DLNDRPVGPRKVKL 998
+ + + R V++
Sbjct: 507 KCHKKNMKDRYVEV 520
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/51 (29%), Positives = 27/51 (52%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMIN 975
T ++ LP++++ +I FF G I ++ N QG GEA+V ++
Sbjct: 225 TVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVS 275
>gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens]
Length = 659
Score = 67.8 bits (164), Expect = 5e-11
Identities = 83/399 (20%), Positives = 163/399 (40%), Gaps = 58/399 (14%)
Query: 77 AEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSINQDAGFHTNG 136
A M + + +++ V R G S V+ + N I ++ E N + + F +
Sbjct: 159 ATMTEYLNFEKSSSVSR----YGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGT 214
Query: 137 TGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNN 194
L +N + RGLP+ ++ D+ FF GL + G + GR N
Sbjct: 215 CSKMELID--------DNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRN 266
Query: 195 GDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHS 254
G+A+V+F S L+ H+ MG+R+IEV + + + +++ G E E
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQ- 325
Query: 255 PPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFF-RGTDLT--D 311
V ++ L + ++ FF + +T
Sbjct: 326 -----------------------------VIVRMRGLPFTATAEEVVAFFGQHCPITGGK 356
Query: 312 EQIRFL-YKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARY 370
E I F+ Y D T AFV+F + AL HK +L R + + + ++ + + R+
Sbjct: 357 EGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRF 416
Query: 371 EKKRSGSLERDRPGHV---SQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFL--L 425
+ + P + Q++ N + CI +R P+ T ++ F +F +
Sbjct: 417 SS--APLIPLPTPPIIPVLPQQFVPPTN--VRDCIRLRGLPYAATIEDILDFLGEFATDI 472
Query: 426 AEDDIYLLYDDKGVGLGEALVKFKSEEQA-MKAERLNRR 463
++++ + +G G+A ++ KS ++A M A++ +++
Sbjct: 473 RTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKK 511
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/236 (24%), Positives = 91/236 (38%), Gaps = 66/236 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISR 59
V+R GLP+ + DI FF GL I GG + G GEA + F ++E A+ R
Sbjct: 226 VVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQR 285
Query: 60 SGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASN 119
+ +E++ ++ + K
Sbjct: 286 HKHHMGTRYIEVYKATGEDFLKIA------------------------------------ 309
Query: 120 SGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-LRGLPYLVNEDDVRVFFSGL 178
G + N+ A F L EN + +RGLP+ ++V FF
Sbjct: 310 ---GGTSNEVAQF-----------------LSKENQVIVRMRGLPFTATAEEVVAFFGQH 349
Query: 179 C-----VDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
C +G++F+ + DGR GDA V FA A L+ H+ +G R+IE+ + +
Sbjct: 350 CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRST 405
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/272 (26%), Positives = 102/272 (37%), Gaps = 69/272 (25%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVH--IIGGEIGEAFIIFATDEDARRAISRS 60
V++R+ GLPF A ++ FF G H I GG+ G I+F T D R
Sbjct: 326 VIVRMRGLPFTATAEEVVAFF--------GQHCPITGGKEG---ILFVTYPDGRPT---G 371
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
F+ L + E + K D +G+ +IE + A+
Sbjct: 372 DAFV--------LFACEEYAQNALRKHKDLLGK--------------RYIELFRSTAAE- 408
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-----------LRGLPYLVNED 169
+ Q N L P T P+ P F LRGLPY +
Sbjct: 409 -----VQQVL----NRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIE 459
Query: 170 DVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDA-SGGLKCHRSFMGSRFIE 224
D+ F D GV + +H GR +GDA ++ S A KCH+ M R++E
Sbjct: 460 DILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVE 519
Query: 225 VMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPP 256
V Q S ++ N V G L R+ PP
Sbjct: 520 VFQCSAEEM-----NFVLMGGTLNRNGLSPPP 546
Score = 39.7 bits (91), Expect = 0.014
Identities = 46/208 (22%), Positives = 80/208 (38%), Gaps = 22/208 (10%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YAFVMFKTLKDYNTALSLH 344
V + L ++D+ FF+G ++ + R A V F + + + AL H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYI 404
K + R + + + + LK G S + +Q + ++ + +
Sbjct: 287 KHHMGTRYIEVYKATGEDFLKIA----------------GGTSNEVAQFLSKENQVIVRM 330
Query: 405 RNFPFDVTKVEVQKFFADFLL----AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERL 460
R PF T EV FF E +++ Y D G G+A V F EE A A R
Sbjct: 331 RGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPD-GRPTGDAFVLFACEEYAQNALRK 389
Query: 461 NRRRFLGTEVLLRLISEAQIQEFGVNFS 488
++ + L + A++Q+ FS
Sbjct: 390 HKDLLGKRYIELFRSTAAEVQQVLNRFS 417
Score = 37.4 bits (85), Expect = 0.071
Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYR--IIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
I++ LP+ A + +ILDF + I V + N QG P+G+A + M + + A A +
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 985 DLNDRPVGPRKVKL 998
+ + + R V++
Sbjct: 507 KCHKKNMKDRYVEV 520
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/51 (29%), Positives = 27/51 (52%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMIN 975
T ++ LP++++ +I FF G I ++ N QG GEA+V ++
Sbjct: 225 TVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVS 275
>gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens]
Length = 608
Score = 67.8 bits (164), Expect = 5e-11
Identities = 83/399 (20%), Positives = 163/399 (40%), Gaps = 58/399 (14%)
Query: 77 AEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSINQDAGFHTNG 136
A M + + +++ V R G S V+ + N I ++ E N + + F +
Sbjct: 159 ATMTEYLNFEKSSSVSR----YGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGT 214
Query: 137 TGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNN 194
L +N + RGLP+ ++ D+ FF GL + G + GR N
Sbjct: 215 CSKMELID--------DNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRN 266
Query: 195 GDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHS 254
G+A+V+F S L+ H+ MG+R+IEV + + + +++ G E E
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQ- 325
Query: 255 PPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFF-RGTDLT--D 311
V ++ L + ++ FF + +T
Sbjct: 326 -----------------------------VIVRMRGLPFTATAEEVVAFFGQHCPITGGK 356
Query: 312 EQIRFL-YKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARY 370
E I F+ Y D T AFV+F + AL HK +L R + + + ++ + + R+
Sbjct: 357 EGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRF 416
Query: 371 EKKRSGSLERDRPGHV---SQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFL--L 425
+ + P + Q++ N + CI +R P+ T ++ F +F +
Sbjct: 417 SS--APLIPLPTPPIIPVLPQQFVPPTN--VRDCIRLRGLPYAATIEDILDFLGEFATDI 472
Query: 426 AEDDIYLLYDDKGVGLGEALVKFKSEEQA-MKAERLNRR 463
++++ + +G G+A ++ KS ++A M A++ +++
Sbjct: 473 RTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKK 511
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/236 (24%), Positives = 91/236 (38%), Gaps = 66/236 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISR 59
V+R GLP+ + DI FF GL I GG + G GEA + F ++E A+ R
Sbjct: 226 VVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQR 285
Query: 60 SGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASN 119
+ +E++ ++ + K
Sbjct: 286 HKHHMGTRYIEVYKATGEDFLKIA------------------------------------ 309
Query: 120 SGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-LRGLPYLVNEDDVRVFFSGL 178
G + N+ A F L EN + +RGLP+ ++V FF
Sbjct: 310 ---GGTSNEVAQF-----------------LSKENQVIVRMRGLPFTATAEEVVAFFGQH 349
Query: 179 C-----VDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
C +G++F+ + DGR GDA V FA A L+ H+ +G R+IE+ + +
Sbjct: 350 CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRST 405
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/272 (26%), Positives = 102/272 (37%), Gaps = 69/272 (25%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVH--IIGGEIGEAFIIFATDEDARRAISRS 60
V++R+ GLPF A ++ FF G H I GG+ G I+F T D R
Sbjct: 326 VIVRMRGLPFTATAEEVVAFF--------GQHCPITGGKEG---ILFVTYPDGRPT---G 371
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
F+ L + E + K D +G+ +IE + A+
Sbjct: 372 DAFV--------LFACEEYAQNALRKHKDLLGK--------------RYIELFRSTAAE- 408
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-----------LRGLPYLVNED 169
+ Q N L P T P+ P F LRGLPY +
Sbjct: 409 -----VQQVL----NRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIE 459
Query: 170 DVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDA-SGGLKCHRSFMGSRFIE 224
D+ F D GV + +H GR +GDA ++ S A KCH+ M R++E
Sbjct: 460 DILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVE 519
Query: 225 VMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPP 256
V Q S ++ N V G L R+ PP
Sbjct: 520 VFQCSAEEM-----NFVLMGGTLNRNGLSPPP 546
Score = 39.7 bits (91), Expect = 0.014
Identities = 46/208 (22%), Positives = 80/208 (38%), Gaps = 22/208 (10%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YAFVMFKTLKDYNTALSLH 344
V + L ++D+ FF+G ++ + R A V F + + + AL H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYI 404
K + R + + + + LK G S + +Q + ++ + +
Sbjct: 287 KHHMGTRYIEVYKATGEDFLKIA----------------GGTSNEVAQFLSKENQVIVRM 330
Query: 405 RNFPFDVTKVEVQKFFADFLL----AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERL 460
R PF T EV FF E +++ Y D G G+A V F EE A A R
Sbjct: 331 RGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPD-GRPTGDAFVLFACEEYAQNALRK 389
Query: 461 NRRRFLGTEVLLRLISEAQIQEFGVNFS 488
++ + L + A++Q+ FS
Sbjct: 390 HKDLLGKRYIELFRSTAAEVQQVLNRFS 417
Score = 37.4 bits (85), Expect = 0.071
Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYR--IIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
I++ LP+ A + +ILDF + I V + N QG P+G+A + M + + A A +
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 985 DLNDRPVGPRKVKL 998
+ + + R V++
Sbjct: 507 KCHKKNMKDRYVEV 520
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/51 (29%), Positives = 27/51 (52%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMIN 975
T ++ LP++++ +I FF G I ++ N QG GEA+V ++
Sbjct: 225 TVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVS 275
>gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens]
Length = 677
Score = 67.8 bits (164), Expect = 5e-11
Identities = 83/399 (20%), Positives = 163/399 (40%), Gaps = 58/399 (14%)
Query: 77 AEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSINQDAGFHTNG 136
A M + + +++ V R G S V+ + N I ++ E N + + F +
Sbjct: 159 ATMTEYLNFEKSSSVSR----YGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGT 214
Query: 137 TGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNN 194
L +N + RGLP+ ++ D+ FF GL + G + GR N
Sbjct: 215 CSKMELID--------DNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRN 266
Query: 195 GDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHS 254
G+A+V+F S L+ H+ MG+R+IEV + + + +++ G E E
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQ- 325
Query: 255 PPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFF-RGTDLT--D 311
V ++ L + ++ FF + +T
Sbjct: 326 -----------------------------VIVRMRGLPFTATAEEVVAFFGQHCPITGGK 356
Query: 312 EQIRFL-YKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARY 370
E I F+ Y D T AFV+F + AL HK +L R + + + ++ + + R+
Sbjct: 357 EGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRF 416
Query: 371 EKKRSGSLERDRPGHV---SQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFL--L 425
+ + P + Q++ N + CI +R P+ T ++ F +F +
Sbjct: 417 SS--APLIPLPTPPIIPVLPQQFVPPTN--VRDCIRLRGLPYAATIEDILDFLGEFATDI 472
Query: 426 AEDDIYLLYDDKGVGLGEALVKFKSEEQA-MKAERLNRR 463
++++ + +G G+A ++ KS ++A M A++ +++
Sbjct: 473 RTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKK 511
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/236 (24%), Positives = 91/236 (38%), Gaps = 66/236 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISR 59
V+R GLP+ + DI FF GL I GG + G GEA + F ++E A+ R
Sbjct: 226 VVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQR 285
Query: 60 SGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASN 119
+ +E++ ++ + K
Sbjct: 286 HKHHMGTRYIEVYKATGEDFLKIA------------------------------------ 309
Query: 120 SGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-LRGLPYLVNEDDVRVFFSGL 178
G + N+ A F L EN + +RGLP+ ++V FF
Sbjct: 310 ---GGTSNEVAQF-----------------LSKENQVIVRMRGLPFTATAEEVVAFFGQH 349
Query: 179 C-----VDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
C +G++F+ + DGR GDA V FA A L+ H+ +G R+IE+ + +
Sbjct: 350 CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRST 405
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/272 (26%), Positives = 102/272 (37%), Gaps = 69/272 (25%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVH--IIGGEIGEAFIIFATDEDARRAISRS 60
V++R+ GLPF A ++ FF G H I GG+ G I+F T D R
Sbjct: 326 VIVRMRGLPFTATAEEVVAFF--------GQHCPITGGKEG---ILFVTYPDGRPT---G 371
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
F+ L + E + K D +G+ +IE + A+
Sbjct: 372 DAFV--------LFACEEYAQNALRKHKDLLGK--------------RYIELFRSTAAE- 408
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-----------LRGLPYLVNED 169
+ Q N L P T P+ P F LRGLPY +
Sbjct: 409 -----VQQVL----NRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIE 459
Query: 170 DVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDA-SGGLKCHRSFMGSRFIE 224
D+ F D GV + +H GR +GDA ++ S A KCH+ M R++E
Sbjct: 460 DILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVE 519
Query: 225 VMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPP 256
V Q S ++ N V G L R+ PP
Sbjct: 520 VFQCSAEEM-----NFVLMGGTLNRNGLSPPP 546
Score = 39.7 bits (91), Expect = 0.014
Identities = 46/208 (22%), Positives = 80/208 (38%), Gaps = 22/208 (10%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YAFVMFKTLKDYNTALSLH 344
V + L ++D+ FF+G ++ + R A V F + + + AL H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYI 404
K + R + + + + LK G S + +Q + ++ + +
Sbjct: 287 KHHMGTRYIEVYKATGEDFLKIA----------------GGTSNEVAQFLSKENQVIVRM 330
Query: 405 RNFPFDVTKVEVQKFFADFLL----AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERL 460
R PF T EV FF E +++ Y D G G+A V F EE A A R
Sbjct: 331 RGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPD-GRPTGDAFVLFACEEYAQNALRK 389
Query: 461 NRRRFLGTEVLLRLISEAQIQEFGVNFS 488
++ + L + A++Q+ FS
Sbjct: 390 HKDLLGKRYIELFRSTAAEVQQVLNRFS 417
Score = 37.4 bits (85), Expect = 0.071
Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYR--IIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
I++ LP+ A + +ILDF + I V + N QG P+G+A + M + + A A +
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 985 DLNDRPVGPRKVKL 998
+ + + R V++
Sbjct: 507 KCHKKNMKDRYVEV 520
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/51 (29%), Positives = 27/51 (52%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMIN 975
T ++ LP++++ +I FF G I ++ N QG GEA+V ++
Sbjct: 225 TVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVS 275
Score = 30.8 bits (68), Expect = 6.7
Identities = 13/38 (34%), Positives = 21/38 (55%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQ 962
T +++ L + V EIL+FF GY+ + I N+Q
Sbjct: 629 TVVRMQGLAYNTGVKEILNFFQGYQYATEDGLIHTNDQ 666
>gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens]
Length = 681
Score = 67.8 bits (164), Expect = 5e-11
Identities = 83/399 (20%), Positives = 163/399 (40%), Gaps = 58/399 (14%)
Query: 77 AEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSINQDAGFHTNG 136
A M + + +++ V R G S V+ + N I ++ E N + + F +
Sbjct: 159 ATMTEYLNFEKSSSVSR----YGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGT 214
Query: 137 TGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNN 194
L +N + RGLP+ ++ D+ FF GL + G + GR N
Sbjct: 215 CSKMELID--------DNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRN 266
Query: 195 GDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHS 254
G+A+V+F S L+ H+ MG+R+IEV + + + +++ G E E
Sbjct: 267 GEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQ- 325
Query: 255 PPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFF-RGTDLT--D 311
V ++ L + ++ FF + +T
Sbjct: 326 -----------------------------VIVRMRGLPFTATAEEVVAFFGQHCPITGGK 356
Query: 312 EQIRFL-YKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARY 370
E I F+ Y D T AFV+F + AL HK +L R + + + ++ + + R+
Sbjct: 357 EGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRF 416
Query: 371 EKKRSGSLERDRPGHV---SQKYSQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFL--L 425
+ + P + Q++ N + CI +R P+ T ++ F +F +
Sbjct: 417 SS--APLIPLPTPPIIPVLPQQFVPPTN--VRDCIRLRGLPYAATIEDILDFLGEFATDI 472
Query: 426 AEDDIYLLYDDKGVGLGEALVKFKSEEQA-MKAERLNRR 463
++++ + +G G+A ++ KS ++A M A++ +++
Sbjct: 473 RTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKK 511
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/236 (24%), Positives = 91/236 (38%), Gaps = 66/236 (27%)
Query: 4 VIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISR 59
V+R GLP+ + DI FF GL I GG + G GEA + F ++E A+ R
Sbjct: 226 VVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQR 285
Query: 60 SGGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASN 119
+ +E++ ++ + K
Sbjct: 286 HKHHMGTRYIEVYKATGEDFLKIA------------------------------------ 309
Query: 120 SGYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-LRGLPYLVNEDDVRVFFSGL 178
G + N+ A F L EN + +RGLP+ ++V FF
Sbjct: 310 ---GGTSNEVAQF-----------------LSKENQVIVRMRGLPFTATAEEVVAFFGQH 349
Query: 179 C-----VDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
C +G++F+ + DGR GDA V FA A L+ H+ +G R+IE+ + +
Sbjct: 350 CPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRST 405
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/272 (26%), Positives = 102/272 (37%), Gaps = 69/272 (25%)
Query: 3 VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVH--IIGGEIGEAFIIFATDEDARRAISRS 60
V++R+ GLPF A ++ FF G H I GG+ G I+F T D R
Sbjct: 326 VIVRMRGLPFTATAEEVVAFF--------GQHCPITGGKEG---ILFVTYPDGRPT---G 371
Query: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120
F+ L + E + K D +G+ +IE + A+
Sbjct: 372 DAFV--------LFACEEYAQNALRKHKDLLGK--------------RYIELFRSTAAE- 408
Query: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLF-----------LRGLPYLVNED 169
+ Q N L P T P+ P F LRGLPY +
Sbjct: 409 -----VQQVL----NRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIE 459
Query: 170 DVRVFFSGLCVD----GVIFLKHHDGRNNGDAIVKFASCVDA-SGGLKCHRSFMGSRFIE 224
D+ F D GV + +H GR +GDA ++ S A KCH+ M R++E
Sbjct: 460 DILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVE 519
Query: 225 VMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPP 256
V Q S ++ N V G L R+ PP
Sbjct: 520 VFQCSAEEM-----NFVLMGGTLNRNGLSPPP 546
Score = 39.7 bits (91), Expect = 0.014
Identities = 46/208 (22%), Positives = 80/208 (38%), Gaps = 22/208 (10%)
Query: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YAFVMFKTLKDYNTALSLH 344
V + L ++D+ FF+G ++ + R A V F + + + AL H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPGHVSQKYSQEGNSGQKLCIYI 404
K + R + + + + LK G S + +Q + ++ + +
Sbjct: 287 KHHMGTRYIEVYKATGEDFLKIA----------------GGTSNEVAQFLSKENQVIVRM 330
Query: 405 RNFPFDVTKVEVQKFFADFLL----AEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERL 460
R PF T EV FF E +++ Y D G G+A V F EE A A R
Sbjct: 331 RGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPD-GRPTGDAFVLFACEEYAQNALRK 389
Query: 461 NRRRFLGTEVLLRLISEAQIQEFGVNFS 488
++ + L + A++Q+ FS
Sbjct: 390 HKDLLGKRYIELFRSTAAEVQQVLNRFS 417
Score = 37.4 bits (85), Expect = 0.071
Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 927 IKIMNLPFKANVNEILDFFHGYR--IIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984
I++ LP+ A + +ILDF + I V + N QG P+G+A + M + + A A +
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 985 DLNDRPVGPRKVKL 998
+ + + R V++
Sbjct: 507 KCHKKNMKDRYVEV 520
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/51 (29%), Positives = 27/51 (52%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMIN 975
T ++ LP++++ +I FF G I ++ N QG GEA+V ++
Sbjct: 225 TVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVS 275
Score = 30.8 bits (68), Expect = 6.7
Identities = 13/38 (34%), Positives = 21/38 (55%)
Query: 925 TPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQ 962
T +++ L + V EIL+FF GY+ + I N+Q
Sbjct: 633 TVVRMQGLAYNTGVKEILNFFQGYQYATEDGLIHTNDQ 670
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 65.5 bits (158), Expect = 2e-10
Identities = 66/206 (32%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 531 LEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRP 590
LE L+QL+ K + E R +E E+ R E+ RR +EE RR
Sbjct: 717 LEQLQQLEKAKAAKL----------EQERREAEMRAKREEEERKRQEELRRQQEEILRRQ 766
Query: 591 SEEDFRRPWEEDF-RRPPEDDFRHPREED--WRRPLEEDWRRPLEEDFR----RSPTEDF 643
EE+ +R EE+ RR E+ R RE++ RR EE+ R+ EE R R E+
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 826
Query: 644 RQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPP 703
R+ EE R+ EE +W EE EE RR E R + R E++ +R
Sbjct: 827 RRKQEELLRKQEEEAAKWAREE------EEAQRRLEENRLRMEEEAARLRHEEEERKRKE 880
Query: 704 EEDFRHSPEEDFRQSPQEHFRRPPQE 729
E R RQ QE RR Q+
Sbjct: 881 LEVQRQKELMRQRQQQQEALRRLQQQ 906
Score = 65.1 bits (157), Expect = 3e-10
Identities = 57/169 (33%), Positives = 80/169 (47%), Gaps = 11/169 (6%)
Query: 571 DFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDF-RHPREEDWRRPLEED--W 627
+ R E+ R R+E+ RR EE RR EE+ +R E++ R +EE RR E++
Sbjct: 739 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIAL 798
Query: 628 RRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEED---WRRPPEEDFR 684
RR EE+ R+ E R+L E R+ EE+ R +E+ R EE+ W R EE R
Sbjct: 799 RRQREEEERQQQEEALRRLEE---RRREEEERR--KQEELLRKQEEEAAKWAREEEEAQR 853
Query: 685 RPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRR 733
R + R E R EE+ + E RQ R+ QE RR
Sbjct: 854 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR 902
Score = 60.8 bits (146), Expect = 6e-09
Identities = 57/172 (33%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 583 REEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDW-RRPLEEDFRRSPTE 641
RE + R EE+ R+ +E+ RR E+ R +EE+ +R EE+ RR EE RR +
Sbjct: 736 REAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQ 794
Query: 642 D--FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQ--GEWRRPPED 697
+ R+ EE+ RQ EE LR L E R EE+ RR EE R+ + +W R E+
Sbjct: 795 EIALRRQREEEERQQQEEALRRLEE----RRREEEERRKQEELLRKQEEEAAKWAREEEE 850
Query: 698 DFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRR 749
RR E R E + +E +R E R+ R+ E RR
Sbjct: 851 AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR 902
Score = 42.0 bits (97), Expect = 0.003
Identities = 53/173 (30%), Positives = 73/173 (42%), Gaps = 24/173 (13%)
Query: 525 ENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPED---FRR 581
E + Q E RQ + Q++ + R E R E E R E RR
Sbjct: 747 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE------EALRRQREQEIALRR 800
Query: 582 PREEDFRRPSEEDFRR----PWEEDFRRPPEDDFRHPREE--DWRRPLEEDWRRPLEEDF 635
REE+ R+ EE RR EE+ RR E+ R EE W R EE+ +R LEE+
Sbjct: 801 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE-EEEAQRRLEENR 859
Query: 636 RRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQ 688
R + EE R EE+ R E + +R E +R +++ R LQ
Sbjct: 860 LR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 904
Score = 36.6 bits (83), Expect = 0.12
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Query: 528 RHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDF 587
R Q E LR+ + +R+ + R E+ + R E+ R+ +EE
Sbjct: 757 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR--RQREEEERQQQEEAL 814
Query: 588 RRPSE----EDFRRPWEEDFRRPPEDDFRHPREEDW-RRPLEEDWRRPLEEDFRRSPTED 642
RR E E+ RR EE R+ E+ + REE+ +R LEE+ R EE R E+
Sbjct: 815 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
Query: 643 FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEW 691
R+ E + ++ E + +++ R ++ ++ + P W
Sbjct: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 923
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 65.5 bits (158), Expect = 2e-10
Identities = 66/206 (32%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 531 LEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRP 590
LE L+QL+ K + E R +E E+ R E+ RR +EE RR
Sbjct: 744 LEQLQQLEKAKAAKL----------EQERREAEMRAKREEEERKRQEELRRQQEEILRRQ 793
Query: 591 SEEDFRRPWEEDF-RRPPEDDFRHPREED--WRRPLEEDWRRPLEEDFR----RSPTEDF 643
EE+ +R EE+ RR E+ R RE++ RR EE+ R+ EE R R E+
Sbjct: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 853
Query: 644 RQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPP 703
R+ EE R+ EE +W EE EE RR E R + R E++ +R
Sbjct: 854 RRKQEELLRKQEEEAAKWAREE------EEAQRRLEENRLRMEEEAARLRHEEEERKRKE 907
Query: 704 EEDFRHSPEEDFRQSPQEHFRRPPQE 729
E R RQ QE RR Q+
Sbjct: 908 LEVQRQKELMRQRQQQQEALRRLQQQ 933
Score = 65.1 bits (157), Expect = 3e-10
Identities = 57/169 (33%), Positives = 80/169 (47%), Gaps = 11/169 (6%)
Query: 571 DFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDF-RHPREEDWRRPLEED--W 627
+ R E+ R R+E+ RR EE RR EE+ +R E++ R +EE RR E++
Sbjct: 766 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIAL 825
Query: 628 RRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEED---WRRPPEEDFR 684
RR EE+ R+ E R+L E R+ EE+ R +E+ R EE+ W R EE R
Sbjct: 826 RRQREEEERQQQEEALRRLEE---RRREEEERR--KQEELLRKQEEEAAKWAREEEEAQR 880
Query: 685 RPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRR 733
R + R E R EE+ + E RQ R+ QE RR
Sbjct: 881 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR 929
Score = 60.8 bits (146), Expect = 6e-09
Identities = 57/172 (33%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 583 REEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDW-RRPLEEDFRRSPTE 641
RE + R EE+ R+ +E+ RR E+ R +EE+ +R EE+ RR EE RR +
Sbjct: 763 REAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQ 821
Query: 642 D--FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQ--GEWRRPPED 697
+ R+ EE+ RQ EE LR L E R EE+ RR EE R+ + +W R E+
Sbjct: 822 EIALRRQREEEERQQQEEALRRLEE----RRREEEERRKQEELLRKQEEEAAKWAREEEE 877
Query: 698 DFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRR 749
RR E R E + +E +R E R+ R+ E RR
Sbjct: 878 AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR 929
Score = 42.0 bits (97), Expect = 0.003
Identities = 53/173 (30%), Positives = 73/173 (42%), Gaps = 24/173 (13%)
Query: 525 ENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPED---FRR 581
E + Q E RQ + Q++ + R E R E E R E RR
Sbjct: 774 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE------EALRRQREQEIALRR 827
Query: 582 PREEDFRRPSEEDFRR----PWEEDFRRPPEDDFRHPREE--DWRRPLEEDWRRPLEEDF 635
REE+ R+ EE RR EE+ RR E+ R EE W R EE+ +R LEE+
Sbjct: 828 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE-EEEAQRRLEENR 886
Query: 636 RRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQ 688
R + EE R EE+ R E + +R E +R +++ R LQ
Sbjct: 887 LR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 931
Score = 36.6 bits (83), Expect = 0.12
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Query: 528 RHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDF 587
R Q E LR+ + +R+ + R E+ + R E+ R+ +EE
Sbjct: 784 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR--RQREEEERQQQEEAL 841
Query: 588 RRPSE----EDFRRPWEEDFRRPPEDDFRHPREEDW-RRPLEEDWRRPLEEDFRRSPTED 642
RR E E+ RR EE R+ E+ + REE+ +R LEE+ R EE R E+
Sbjct: 842 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
Query: 643 FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEW 691
R+ E + ++ E + +++ R ++ ++ + P W
Sbjct: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 950
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 65.5 bits (158), Expect = 2e-10
Identities = 66/206 (32%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 531 LEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRP 590
LE L+QL+ K + E R +E E+ R E+ RR +EE RR
Sbjct: 723 LEQLQQLEKAKAAKL----------EQERREAEMRAKREEEERKRQEELRRQQEEILRRQ 772
Query: 591 SEEDFRRPWEEDF-RRPPEDDFRHPREED--WRRPLEEDWRRPLEEDFR----RSPTEDF 643
EE+ +R EE+ RR E+ R RE++ RR EE+ R+ EE R R E+
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE 832
Query: 644 RQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPP 703
R+ EE R+ EE +W EE EE RR E R + R E++ +R
Sbjct: 833 RRKQEELLRKQEEEAAKWAREE------EEAQRRLEENRLRMEEEAARLRHEEEERKRKE 886
Query: 704 EEDFRHSPEEDFRQSPQEHFRRPPQE 729
E R RQ QE RR Q+
Sbjct: 887 LEVQRQKELMRQRQQQQEALRRLQQQ 912
Score = 65.1 bits (157), Expect = 3e-10
Identities = 57/169 (33%), Positives = 80/169 (47%), Gaps = 11/169 (6%)
Query: 571 DFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDF-RHPREEDWRRPLEED--W 627
+ R E+ R R+E+ RR EE RR EE+ +R E++ R +EE RR E++
Sbjct: 745 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIAL 804
Query: 628 RRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEED---WRRPPEEDFR 684
RR EE+ R+ E R+L E R+ EE+ R +E+ R EE+ W R EE R
Sbjct: 805 RRQREEEERQQQEEALRRLEE---RRREEEERR--KQEELLRKQEEEAAKWAREEEEAQR 859
Query: 685 RPLQGEWRRPPEDDFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRR 733
R + R E R EE+ + E RQ R+ QE RR
Sbjct: 860 RLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR 908
Score = 60.8 bits (146), Expect = 6e-09
Identities = 57/172 (33%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 583 REEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDW-RRPLEEDFRRSPTE 641
RE + R EE+ R+ +E+ RR E+ R +EE+ +R EE+ RR EE RR +
Sbjct: 742 REAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQ 800
Query: 642 D--FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQ--GEWRRPPED 697
+ R+ EE+ RQ EE LR L E R EE+ RR EE R+ + +W R E+
Sbjct: 801 EIALRRQREEEERQQQEEALRRLEE----RRREEEERRKQEELLRKQEEEAAKWAREEEE 856
Query: 698 DFRRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRR 749
RR E R E + +E +R E R+ R+ E RR
Sbjct: 857 AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR 908
Score = 42.0 bits (97), Expect = 0.003
Identities = 53/173 (30%), Positives = 73/173 (42%), Gaps = 24/173 (13%)
Query: 525 ENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPED---FRR 581
E + Q E RQ + Q++ + R E R E E R E RR
Sbjct: 753 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE------EALRRQREQEIALRR 806
Query: 582 PREEDFRRPSEEDFRR----PWEEDFRRPPEDDFRHPREE--DWRRPLEEDWRRPLEEDF 635
REE+ R+ EE RR EE+ RR E+ R EE W R EE+ +R LEE+
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE-EEEAQRRLEENR 865
Query: 636 RRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQ 688
R + EE R EE+ R E + +R E +R +++ R LQ
Sbjct: 866 LR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 910
Score = 36.6 bits (83), Expect = 0.12
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Query: 528 RHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDF 587
R Q E LR+ + +R+ + R E+ + R E+ R+ +EE
Sbjct: 763 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR--RQREEEERQQQEEAL 820
Query: 588 RRPSE----EDFRRPWEEDFRRPPEDDFRHPREEDW-RRPLEEDWRRPLEEDFRRSPTED 642
RR E E+ RR EE R+ E+ + REE+ +R LEE+ R EE R E+
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Query: 643 FRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEW 691
R+ E + ++ E + +++ R ++ ++ + P W
Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.141 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,112,946
Number of Sequences: 37866
Number of extensions: 3567232
Number of successful extensions: 17311
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 10686
Number of HSP's gapped (non-prelim): 3219
length of query: 1001
length of database: 18,247,518
effective HSP length: 112
effective length of query: 889
effective length of database: 14,006,526
effective search space: 12451801614
effective search space used: 12451801614
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.