Search of human proteins with 10835169

Search of human proteins with 10835169

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835169 solute carrier family 11 (proton-coupled divalent
metal ion transporters), member 2 [Homo sapiens]
         (561 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835169 solute carrier family 11 (proton-coupled divalent me...  1111   0.0  
gi|109255241 natural resistance-associated macrophage protein 1 ...   696   0.0  
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...    32   1.2  
gi|189571629 membrane bound O-acyltransferase domain containing ...    32   1.5  
gi|144953907 major facilitator superfamily domain containing 6 [...    32   2.0  
gi|15718767 TRAAK [Homo sapiens]                                       32   2.0  
gi|53793673 olfactory receptor, family 10, subfamily C, member 1...    31   2.6  
gi|37187860 chemokine (C-C motif) receptor 6 [Homo sapiens]            30   7.7  
gi|37188165 chemokine (C-C motif) receptor 6 [Homo sapiens]            30   7.7  
gi|42518076 testis expressed sequence 261 [Homo sapiens]               30   7.7  

>gi|10835169 solute carrier family 11 (proton-coupled divalent metal
           ion transporters), member 2 [Homo sapiens]
          Length = 561

 Score = 1111 bits (2874), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 60
           MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE
Sbjct: 1   MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE 60

Query: 61  EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 120
           EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR
Sbjct: 61  EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR 120

Query: 121 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 180
           LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI
Sbjct: 121 LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI 180

Query: 181 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 240
           PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM
Sbjct: 181 PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM 240

Query: 241 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 300
           FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES
Sbjct: 241 FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES 300

Query: 301 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 360
           CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG
Sbjct: 301 CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG 360

Query: 361 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 420
           VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI
Sbjct: 361 VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI 420

Query: 421 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 480
           IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG
Sbjct: 421 IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG 480

Query: 481 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 540
           GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC
Sbjct: 481 GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC 540

Query: 541 GHTVSISKGLLTEEATRGYVK 561
           GHTVSISKGLLTEEATRGYVK
Sbjct: 541 GHTVSISKGLLTEEATRGYVK 561


>gi|109255241 natural resistance-associated macrophage protein 1
           [Homo sapiens]
          Length = 550

 Score =  696 bits (1797), Expect = 0.0
 Identities = 346/543 (63%), Positives = 430/543 (79%), Gaps = 2/543 (0%)

Query: 14  VSGDHGESASLGNINPAYSNPSLSQSPGDSEEY-FATYFNEKISIPEEEYSCFSFRKLWA 72
           ++GD G     G+   + S+P+   SPG  +     TY +EKI IP+ +   FS RKLWA
Sbjct: 1   MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLSEKIPIPDTKPGTFSLRKLWA 60

Query: 73  FTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLH 132
           FTGPGFLMSIA+LDPGNIESDLQ+GAVAGFKLLW+LL AT++GLL QRLAARLGVVTG  
Sbjct: 61  FTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKD 120

Query: 133 LAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIAD 192
           L EVCH  YPKVPR +LWL +ELAI+GSDMQEVIG+AIA NLLS GRIPLWGGVLITI D
Sbjct: 121 LGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVD 180

Query: 193 TFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQ 252
           TF FLFLD YGLRKLEAFFG LITIMALTFGYEYV  +P Q  +L+G+F+PSC GC  P+
Sbjct: 181 TFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPE 240

Query: 253 IEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINV 312
           + QAVGIVGA+IMPHN+YLHSALVKSR+++R  + ++REAN YF IE+ IAL VSFIIN+
Sbjct: 241 LLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRADIREANMYFLIEATIALSVSFIINL 300

Query: 313 FVVSVFAEAFFGKTNEQVVEVCTNTS-SPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAA 371
           FV++VF +AF+ KTN+    +C N+S   +A +FP +N+T+AVDIY+GGV+LGC FGPAA
Sbjct: 301 FVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGVILGCLFGPAA 360

Query: 372 LYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQD 431
           LYIWA+G+LAAGQSSTMTGTY+GQFVMEGFL L+WSRFARV+LTRS AI+PT+LVAVF+D
Sbjct: 361 LYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRD 420

Query: 432 VEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSIN 491
           +  L+G+ND LNVLQSL LPFA++PILTFTS+  +M +FANGL  ++    +++++C+IN
Sbjct: 421 LRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAIN 480

Query: 492 MYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDCGHTVSISKGLL 551
           +YFVV Y+  L H A + +AA+++ AYLG   YL W C +A G +FL          GLL
Sbjct: 481 LYFVVSYLPSLPHPAYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHSSHHHFLYGLL 540

Query: 552 TEE 554
            E+
Sbjct: 541 EED 543


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
           plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/50 (32%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 244 SCSGCRTPQIEQAVGIV-GAVIMPHNMYLHSALVKSRQVNRNNKQEVREA 292
           SC   + P I+ A+ ++  AVI+PH+ + +S L   R++  ++ Q +R A
Sbjct: 666 SCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNA 715


>gi|189571629 membrane bound O-acyltransferase domain containing 4
           [Homo sapiens]
          Length = 435

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 4/98 (4%)

Query: 442 LNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRD 501
           ++  Q    PFAL+    +  +    S  A  L     GG L   + ++  Y V+V+   
Sbjct: 12  ISFYQGAAFPFALL--FNYLCIMDSFSTRARYLFLLTGGGALA--VAAMGSYAVLVFTPA 67

Query: 502 LGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLD 539
           +  VAL    A   V    F F + WQ L  LG+ + +
Sbjct: 68  VCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTE 105


>gi|144953907 major facilitator superfamily domain containing 6
           [Homo sapiens]
          Length = 791

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 35/154 (22%)

Query: 161 DMQEVIGSAIAINLLSVGRI-PLWGGVLITIADTFVFLFL----DKYGLRKLEAFFGFLI 215
           D QEV   AI + +L V  I   +    +TI DT    +L    D+YGL+++    G+ +
Sbjct: 280 DQQEV--EAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGL 337

Query: 216 TIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIE--QAVGIVGAVIMPHNMYLHS 273
            ++++  G +Y  ++     ++ G       GC+ P+    Q V IV  V+M   + + +
Sbjct: 338 AMLSVGIGIDYTHIE----VLIDG------KGCKPPEYRNYQIVFIVFGVLMTMALIVAT 387

Query: 274 AL----------------VKSRQVNRNNKQEVRE 291
                             V+  QV RNN  E  E
Sbjct: 388 QFRFRYNHFKNDDSKGKEVEIPQVERNNSTESSE 421


>gi|15718767 TRAAK [Homo sapiens]
          Length = 393

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 172 INLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKP 231
           + +LS     L G +L  +  TFVF +++ +   KLEA +  ++T+  + FG       P
Sbjct: 167 VRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWS--KLEAIYFVIVTLTTVGFGDYVAGADP 224

Query: 232 SQ 233
            Q
Sbjct: 225 RQ 226


>gi|53793673 olfactory receptor, family 10, subfamily C, member 1
           [Homo sapiens]
          Length = 312

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 21/62 (33%), Positives = 28/62 (45%)

Query: 187 LITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCS 246
           L+T+A  F+ + L           + FL T+ AL  GY  VTV      +L G    S S
Sbjct: 35  LLTVAGNFLIVVLVSTDAALQSPMYFFLRTLSALEIGYTSVTVPLLLHHLLTGRRHISRS 94

Query: 247 GC 248
           GC
Sbjct: 95  GC 96


>gi|37187860 chemokine (C-C motif) receptor 6 [Homo sapiens]
          Length = 374

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 21/89 (23%)

Query: 207 LEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIM- 265
           LE  FGF I +M + F Y ++     Q+Q  K                +A+ ++ AV++ 
Sbjct: 217 LELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKR--------------HKAIRVIIAVVLV 262

Query: 266 ------PHNMYLHSALVKSRQVNRNNKQE 288
                 PHNM L        ++NR+ + E
Sbjct: 263 FLACQIPHNMVLLVTAANLGKMNRSCQSE 291


>gi|37188165 chemokine (C-C motif) receptor 6 [Homo sapiens]
          Length = 374

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 21/89 (23%)

Query: 207 LEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIM- 265
           LE  FGF I +M + F Y ++     Q+Q  K                +A+ ++ AV++ 
Sbjct: 217 LELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKR--------------HKAIRVIIAVVLV 262

Query: 266 ------PHNMYLHSALVKSRQVNRNNKQE 288
                 PHNM L        ++NR+ + E
Sbjct: 263 FLACQIPHNMVLLVTAANLGKMNRSCQSE 291


>gi|42518076 testis expressed sequence 261 [Homo sapiens]
          Length = 196

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 22/140 (15%)

Query: 105 LWILLLATLVGLLLQRLAARLGVVTGL-HLAEVCHRQYPKVPRVI---LW----LMVELA 156
           +W + L + + L +Q     L V  GL +LAE+         R+I   +W    +++ L 
Sbjct: 1   MWFMYLLSWLSLFIQVAFITLAVAAGLYYLAELIEEYTVATSRIIKYMIWFSTAVLIGLY 60

Query: 157 IIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIAD--------------TFVFLFLDKY 202
           +       +IG  +  NL+  G +  +  +++T  +               F F   + Y
Sbjct: 61  VFERFPTSMIGVGLFTNLVYFGLLQTFPFIMLTSPNFILSCGLVVVNHYLAFQFFAEEYY 120

Query: 203 GLRKLEAFFGFLITIMALTF 222
              ++ A+F F + I+   F
Sbjct: 121 PFSEVLAYFTFCLWIIPFAF 140


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,320,835
Number of Sequences: 37866
Number of extensions: 803004
Number of successful extensions: 2163
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2158
Number of HSP's gapped (non-prelim): 10
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.