Guide to the Human Genome
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Search of human proteins with 116812636

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812636 O-sialoglycoprotein endopeptidase-like 1 [Homo
sapiens]
         (414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812636 O-sialoglycoprotein endopeptidase-like 1 [Homo sapi...   823   0.0  
gi|8923380 O-sialoglycoprotein endopeptidase [Homo sapiens]           108   7e-24
gi|239752808 PREDICTED: similar to c-jun [Homo sapiens]                33   0.47 
gi|239747354 PREDICTED: hypothetical protein XP_002346430 [Homo ...    33   0.47 
gi|239741179 PREDICTED: hypothetical protein XP_002342128 [Homo ...    33   0.47 
gi|55743075 angio-associated, migratory cell protein [Homo sapiens]    32   1.4  
gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]    31   1.8  
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ...    30   5.2  
gi|14589900 mitogen-activated protein kinase kinase 6 [Homo sapi...    29   6.9  
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]           29   9.0  
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]           29   9.0  
gi|17998698 GATA binding protein 5 [Homo sapiens]                      29   9.0  

>gi|116812636 O-sialoglycoprotein endopeptidase-like 1 [Homo
           sapiens]
          Length = 414

 Score =  823 bits (2125), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MLILTKTAGVFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNV 60
           MLILTKTAGVFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNV
Sbjct: 1   MLILTKTAGVFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNV 60

Query: 61  LGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGL 120
           LGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGL
Sbjct: 61  LGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGL 120

Query: 121 ALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALV 180
           ALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALV
Sbjct: 121 ALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALV 180

Query: 181 QGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIK 240
           QGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIK
Sbjct: 181 QGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIK 240

Query: 241 PPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKR 300
           PPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKR
Sbjct: 241 PPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKR 300

Query: 301 THRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNG 360
           THRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNG
Sbjct: 301 THRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNG 360

Query: 361 IMIAWNGIERLRAGLGILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI 414
           IMIAWNGIERLRAGLGILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI
Sbjct: 361 IMIAWNGIERLRAGLGILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI 414


>gi|8923380 O-sialoglycoprotein endopeptidase [Homo sapiens]
          Length = 335

 Score =  108 bits (271), Expect = 7e-24
 Identities = 99/337 (29%), Positives = 155/337 (45%), Gaps = 31/337 (9%)

Query: 39  VLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEA 98
           VLG E S +     VV + G VL      +T V     G +P    + HR  I  ++QEA
Sbjct: 4   VLGFEGSANKIGVGVVRD-GKVLANP--RRTYVTPPGTGFLPGDTARHHRAVILDLLQEA 60

Query: 99  LSASGVSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQL-KKPFIPIHHMEAHALTIRL 157
           L+ SG++  D+  IA T  PG+   L V ++   + V QL  KP + ++H   H    RL
Sbjct: 61  LTESGLTSQDIDCIAYTKGPGMGAPL-VSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRL 119

Query: 158 TNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECS 217
                 P  VL +SGG+  + +      + + G+++DIA G+ LD+ AR L +   P   
Sbjct: 120 ITGATSP-TVLYVSGGNTQV-IAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDP--- 174

Query: 218 TMSGGKAIEHLAKQGNRFHFDIKPPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQ 277
             S G  IE +AK+G +    ++ P +  K  D SF+G+    + +  +      +  G+
Sbjct: 175 --SPGYNIEQMAKRGKKL---VELP-YTVKGMDVSFSGILSFIEDVAHRM-----LATGE 223

Query: 278 ILSSAADIAATVQHTMACHLVKRTHRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRAL 337
              +  D+  ++Q T+   LV+ T RA+  C  ++ L          GGV  N  ++  +
Sbjct: 224 --CTPEDLCFSLQETVFAMLVEITERAMAHCGSQEAL--------IVGGVGCNVRLQEMM 273

Query: 338 EILTNATQCTLLCPPPRLCTDNGIMIAWNGIERLRAG 374
             +       L     R C DNG MIA  G E  RAG
Sbjct: 274 ATMCQERGARLFATDERFCIDNGAMIAQAGWEMFRAG 310


>gi|239752808 PREDICTED: similar to c-jun [Homo sapiens]
          Length = 324

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 25/97 (25%)

Query: 127 GLSFSLQLVGQLKKPFIPIHHMEA--HALTIRLTNKVEFPFLVLLISGG----------H 174
           G  F LQ    L+ PF  +   +A  HAL +RL      P L L + GG          H
Sbjct: 105 GFHFFLQPGDSLQLPFSALGGSDAVPHALPLRLD-----PLLGLHVDGGQGRCLAGHLGH 159

Query: 175 CLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLI 211
           CL  L+QG+   +L         G +L +V RRL L+
Sbjct: 160 CLRLLLQGLQPRVL--------HGHLLGQVVRRLLLL 188


>gi|239747354 PREDICTED: hypothetical protein XP_002346430 [Homo
           sapiens]
          Length = 324

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 25/97 (25%)

Query: 127 GLSFSLQLVGQLKKPFIPIHHMEA--HALTIRLTNKVEFPFLVLLISGG----------H 174
           G  F LQ    L+ PF  +   +A  HAL +RL      P L L + GG          H
Sbjct: 105 GFHFFLQPGDSLQLPFSALGGSDAVPHALPLRLD-----PLLGLHVDGGQGRCLAGHLGH 159

Query: 175 CLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLI 211
           CL  L+QG+   +L         G +L +V RRL L+
Sbjct: 160 CLRLLLQGLQPRVL--------HGHLLGQVVRRLLLL 188


>gi|239741179 PREDICTED: hypothetical protein XP_002342128 [Homo
           sapiens]
          Length = 324

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 25/97 (25%)

Query: 127 GLSFSLQLVGQLKKPFIPIHHMEA--HALTIRLTNKVEFPFLVLLISGG----------H 174
           G  F LQ    L+ PF  +   +A  HAL +RL      P L L + GG          H
Sbjct: 105 GFHFFLQPGDSLQLPFSALGGSDAVPHALPLRLD-----PLLGLHVDGGQGRCLAGHLGH 159

Query: 175 CLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLI 211
           CL  L+QG+   +L         G +L +V RRL L+
Sbjct: 160 CLRLLLQGLQPRVL--------HGHLLGQVVRRLLLL 188


>gi|55743075 angio-associated, migratory cell protein [Homo sapiens]
          Length = 434

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 257 QHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKRTHRAILFCKQRDLLPQ 316
           Q + D    ++E+EEG E+G +L     +  +++      +    H A +FC   D  P+
Sbjct: 45  QEMEDVDFEEEEEEEGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLD--PK 102

Query: 317 NNAVLVASG 325
            N + V  G
Sbjct: 103 TNTLAVTGG 111


>gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]
          Length = 1603

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 4/76 (5%)

Query: 282 AADIAATVQHTMACHLVKRTHRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILT 341
           AA+ A     TMA   VK+  R     KQ+   PQ +    A+   A    +   L  L 
Sbjct: 568 AAEAATVAAATMAMPEVKKRRRR----KQKLASPQPSYAADANDSKAEYSDVLAKLAFLN 623

Query: 342 NATQCTLLCPPPRLCT 357
             +QC   C PPR  T
Sbjct: 624 RQSQCAGRCSPPRCWT 639


>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
            sapiens]
          Length = 1726

 Score = 29.6 bits (65), Expect = 5.2
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 6/87 (6%)

Query: 28   FHPGTLFLHKIVLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLH 87
            FHPG  +     +  E   D T  +V   TG  +   I       LK+GG  PP++Q   
Sbjct: 1386 FHPGVPWKGLQNIDPENDPDVTPGSV--PTGPTINTTIQDVNRYLLKSGGSSPPSSQ--- 1440

Query: 88   RENIQRIVQEALSASGVSPSDLSAIAT 114
               +       LSASG S S  S+IA+
Sbjct: 1441 NATLPSSSAWPLSASGYS-SSFSSIAS 1466


>gi|14589900 mitogen-activated protein kinase kinase 6 [Homo
           sapiens]
          Length = 334

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 19/65 (29%)

Query: 197 PGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIKP------PLHHAKNCD 250
           P D+L K+A  +S++K           A+EHL  + +  H D+KP       L   K CD
Sbjct: 151 PEDILGKIA--VSIVK-----------ALEHLHSKLSVIHRDVKPSNVLINALGQVKMCD 197

Query: 251 FSFTG 255
           F  +G
Sbjct: 198 FGISG 202


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 319  AVLVASGGVASNFYIRRALEILTNATQCTLLCP------PPRLCTDNGIMIAWNGIERLR 372
            A+L+ S  V S + + +AL +L   T  + LCP       P LC     +  W     LR
Sbjct: 4043 AILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLCVGLWALRLWGA---LR 4099

Query: 373  AGLGIL----HDIEGIRYEP 388
             G  IL    H + G  Y P
Sbjct: 4100 LGAVILRWRYHALRGELYRP 4119


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 319  AVLVASGGVASNFYIRRALEILTNATQCTLLCP------PPRLCTDNGIMIAWNGIERLR 372
            A+L+ S  V S + + +AL +L   T  + LCP       P LC     +  W     LR
Sbjct: 4044 AILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLCVGLWALRLWGA---LR 4100

Query: 373  AGLGIL----HDIEGIRYEP 388
             G  IL    H + G  Y P
Sbjct: 4101 LGAVILRWRYHALRGELYRP 4120


>gi|17998698 GATA binding protein 5 [Homo sapiens]
          Length = 397

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 19/105 (18%)

Query: 59  NVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQ------RIVQEALSASG--------- 103
           N  GE + +   +++K  G+  P A +  +E+IQ      + + +A  +SG         
Sbjct: 257 NSEGEPVCNACGLYMKLHGVPRPLAMK--KESIQTRKRKPKTIAKARGSSGSTRNASASP 314

Query: 104 --VSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQLKKPFIPIH 146
             V+ +D SA  +  KP LA  +  G S + Q  GQ      P H
Sbjct: 315 SAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGH 359


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,787,076
Number of Sequences: 37866
Number of extensions: 678110
Number of successful extensions: 1484
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1474
Number of HSP's gapped (non-prelim): 15
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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