Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116536083
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116536083 phosphodiesterase 11A isoform 1 [Homo sapiens]
(489 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116536089 phosphodiesterase 11A isoform 2 [Homo sapiens] 981 0.0
gi|116536087 phosphodiesterase 11A isoform 3 [Homo sapiens] 981 0.0
gi|116536083 phosphodiesterase 11A isoform 1 [Homo sapiens] 981 0.0
gi|116536085 phosphodiesterase 11A isoform 4 [Homo sapiens] 981 0.0
gi|61744435 phosphodiesterase 5A isoform 1 [Homo sapiens] 410 e-114
gi|61744432 phosphodiesterase 5A isoform 3 [Homo sapiens] 410 e-114
gi|61744430 phosphodiesterase 5A isoform 2 [Homo sapiens] 410 e-114
gi|170650674 phosphodiesterase 6A [Homo sapiens] 334 9e-92
gi|157364939 phosphodiesterase 6C [Homo sapiens] 329 4e-90
gi|223718037 phosphodiesterase 6B isoform 2 [Homo sapiens] 326 3e-89
gi|223718019 phosphodiesterase 6B isoform 3 [Homo sapiens] 326 3e-89
gi|105990537 phosphodiesterase 6B isoform 1 [Homo sapiens] 326 3e-89
gi|5729972 phosphodiesterase 10A isoform 2 [Homo sapiens] 319 4e-87
gi|194595488 phosphodiesterase 10A isoform 1 [Homo sapiens] 319 4e-87
gi|226246591 phosphodiesterase 2A isoform 3 [Homo sapiens] 303 2e-82
gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens] 303 2e-82
gi|4505657 phosphodiesterase 2A isoform 1 [Homo sapiens] 303 2e-82
gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens] 159 7e-39
gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens] 159 7e-39
gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens] 159 7e-39
gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens] 159 7e-39
gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens] 159 7e-39
gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens] 159 7e-39
gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens] 159 7e-39
gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens] 159 7e-39
gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens] 159 7e-39
gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens] 159 7e-39
gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens] 159 7e-39
gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens] 159 7e-39
gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens] 159 7e-39
>gi|116536089 phosphodiesterase 11A isoform 2 [Homo sapiens]
Length = 575
Score = 981 bits (2537), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 60
MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI
Sbjct: 87 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 146
Query: 61 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY
Sbjct: 147 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 206
Query: 121 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 180
DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI
Sbjct: 207 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 266
Query: 181 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 240
TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG
Sbjct: 267 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 326
Query: 241 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 300
FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI
Sbjct: 327 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 386
Query: 301 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 360
LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR
Sbjct: 387 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 446
Query: 361 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 420
DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE
Sbjct: 447 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 506
Query: 421 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 480
LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS
Sbjct: 507 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 566
Query: 481 VMVAKEDRN 489
VMVAKEDRN
Sbjct: 567 VMVAKEDRN 575
>gi|116536087 phosphodiesterase 11A isoform 3 [Homo sapiens]
Length = 683
Score = 981 bits (2537), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 60
MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI
Sbjct: 195 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 254
Query: 61 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY
Sbjct: 255 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 314
Query: 121 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 180
DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI
Sbjct: 315 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 374
Query: 181 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 240
TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG
Sbjct: 375 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 434
Query: 241 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 300
FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI
Sbjct: 435 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 494
Query: 301 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 360
LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR
Sbjct: 495 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 554
Query: 361 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 420
DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE
Sbjct: 555 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 614
Query: 421 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 480
LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS
Sbjct: 615 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 674
Query: 481 VMVAKEDRN 489
VMVAKEDRN
Sbjct: 675 VMVAKEDRN 683
Score = 74.3 bits (181), Expect = 2e-13
Identities = 31/91 (34%), Positives = 64/91 (70%), Gaps = 1/91 (1%)
Query: 49 QDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRL-DGKPFDDADQRLFEAFV 107
+D RF+ E D+++G+ +S+LC+PI +S+ +IIGVAQ +N++ +G PF + D+++ + ++
Sbjct: 54 KDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYL 113
Query: 108 IFCGLGINNTIMYDQVKKSWAKQSVALDVLS 138
FCG+ I+N ++ +K + + L+V++
Sbjct: 114 PFCGIAISNAQLFAASRKEYERSRALLEVVN 144
>gi|116536083 phosphodiesterase 11A isoform 1 [Homo sapiens]
Length = 489
Score = 981 bits (2537), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 60
MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI
Sbjct: 1 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 60
Query: 61 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY
Sbjct: 61 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
Query: 121 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 180
DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI
Sbjct: 121 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 180
Query: 181 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 240
TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG
Sbjct: 181 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 240
Query: 241 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 300
FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI
Sbjct: 241 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 300
Query: 301 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 360
LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR
Sbjct: 301 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 360
Query: 361 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 420
DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE
Sbjct: 361 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 420
Query: 421 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 480
LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS
Sbjct: 421 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 480
Query: 481 VMVAKEDRN 489
VMVAKEDRN
Sbjct: 481 VMVAKEDRN 489
>gi|116536085 phosphodiesterase 11A isoform 4 [Homo sapiens]
Length = 933
Score = 981 bits (2537), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 60
MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI
Sbjct: 445 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI 504
Query: 61 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY
Sbjct: 505 SGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 564
Query: 121 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 180
DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI
Sbjct: 565 DQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMI 624
Query: 181 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 240
TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG
Sbjct: 625 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 684
Query: 241 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 300
FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI
Sbjct: 685 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 744
Query: 301 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 360
LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR
Sbjct: 745 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHR 804
Query: 361 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 420
DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE
Sbjct: 805 DIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDE 864
Query: 421 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 480
LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS
Sbjct: 865 LPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSPAS 924
Query: 481 VMVAKEDRN 489
VMVAKEDRN
Sbjct: 925 VMVAKEDRN 933
Score = 89.0 bits (219), Expect = 9e-18
Identities = 40/105 (38%), Positives = 72/105 (68%), Gaps = 1/105 (0%)
Query: 35 VASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRL-DGK 93
V G VNI DAYQD RF+ E D+++G+ +S+LC+PI +S+ +IIGVAQ +N++ +G
Sbjct: 290 VGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGA 349
Query: 94 PFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLS 138
PF + D+++ + ++ FCG+ I+N ++ +K + + L+V++
Sbjct: 350 PFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVN 394
>gi|61744435 phosphodiesterase 5A isoform 1 [Homo sapiens]
Length = 875
Score = 410 bits (1054), Expect = e-114
Identities = 214/473 (45%), Positives = 310/473 (65%), Gaps = 20/473 (4%)
Query: 15 ESMEKSS------YSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFH---I 65
E +EKSS + IN A+ V +T P+NI D +D RF + + I
Sbjct: 389 EELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCI 448
Query: 66 RSVLCVPIWNSN-HQIIGVAQVLNRLDG-----KPFDDADQRLFEAFVIFCGLGINNTIM 119
RS+LC PI N +++IGV Q++N+++ KPF+ D++ EAFVIFCGLGI NT M
Sbjct: 449 RSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQM 508
Query: 120 YDQVKKSWAKQSVALDVLSYHATCSKAEVDKFK---AANIPLVSELAIDDIHFDDFSLDV 176
Y+ V+++ AKQ V L+VLSYHA+ ++ E + + AA +P L I D F DF L
Sbjct: 509 YEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSD 568
Query: 177 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM-VLYHNWRHAFNVCQLMFAM 235
+RMF +L +VQ F++ +E LCRW+L+V+KNYR V YHNWRHAFN Q MFA
Sbjct: 569 LETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAA 628
Query: 236 LTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFN 295
L Q+ LT++EILA+++ L HDLDHRG NN++ +S LAQLY S +EHHHF+
Sbjct: 629 LKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSI-MEHHHFD 687
Query: 296 HAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 355
+MIL S G+ I + LS +EY ++++KQ+ILATDL LY +RR EFFEL+ K +++
Sbjct: 688 QCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLE 747
Query: 356 IKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDR 415
+ +++F +MLMTACDL A+TKPW I +++AELV +EFF+QGDRER EL + P+ + +R
Sbjct: 748 DPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNR 807
Query: 416 NRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKR 468
+K+++P +Q+ +ID+IC+ LY+AL V+ P+LD NR KW+ L +++
Sbjct: 808 EKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQ 860
Score = 97.4 bits (241), Expect = 3e-20
Identities = 51/133 (38%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Query: 9 AENSFKESMEKSSYS-DWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRS 67
AE S E + + +W N I VA+ G P+NI DAY+DPRF+AE DQI+G+ +S
Sbjct: 208 AEGSTLEEVSNNCIRLEW--NKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQS 265
Query: 68 VLCVPIWNSNHQIIGVAQVLNRLDGK--PFDDADQRLFEAFVIFCGLGINNTIMYDQVKK 125
+LC+PI N +++GVAQ +N+ G F + D++ F A++ FCG+ ++N +Y+
Sbjct: 266 ILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLL 325
Query: 126 SWAKQSVALDVLS 138
+ V LD+ S
Sbjct: 326 ENKRNQVLLDLAS 338
>gi|61744432 phosphodiesterase 5A isoform 3 [Homo sapiens]
Length = 823
Score = 410 bits (1054), Expect = e-114
Identities = 214/473 (45%), Positives = 310/473 (65%), Gaps = 20/473 (4%)
Query: 15 ESMEKSS------YSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFH---I 65
E +EKSS + IN A+ V +T P+NI D +D RF + + I
Sbjct: 337 EELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCI 396
Query: 66 RSVLCVPIWNSN-HQIIGVAQVLNRLDG-----KPFDDADQRLFEAFVIFCGLGINNTIM 119
RS+LC PI N +++IGV Q++N+++ KPF+ D++ EAFVIFCGLGI NT M
Sbjct: 397 RSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQM 456
Query: 120 YDQVKKSWAKQSVALDVLSYHATCSKAEVDKFK---AANIPLVSELAIDDIHFDDFSLDV 176
Y+ V+++ AKQ V L+VLSYHA+ ++ E + + AA +P L I D F DF L
Sbjct: 457 YEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSD 516
Query: 177 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM-VLYHNWRHAFNVCQLMFAM 235
+RMF +L +VQ F++ +E LCRW+L+V+KNYR V YHNWRHAFN Q MFA
Sbjct: 517 LETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAA 576
Query: 236 LTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFN 295
L Q+ LT++EILA+++ L HDLDHRG NN++ +S LAQLY S +EHHHF+
Sbjct: 577 LKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSI-MEHHHFD 635
Query: 296 HAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 355
+MIL S G+ I + LS +EY ++++KQ+ILATDL LY +RR EFFEL+ K +++
Sbjct: 636 QCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLE 695
Query: 356 IKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDR 415
+ +++F +MLMTACDL A+TKPW I +++AELV +EFF+QGDRER EL + P+ + +R
Sbjct: 696 DPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNR 755
Query: 416 NRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKR 468
+K+++P +Q+ +ID+IC+ LY+AL V+ P+LD NR KW+ L +++
Sbjct: 756 EKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQ 808
Score = 97.4 bits (241), Expect = 3e-20
Identities = 51/133 (38%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Query: 9 AENSFKESMEKSSYS-DWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRS 67
AE S E + + +W N I VA+ G P+NI DAY+DPRF+AE DQI+G+ +S
Sbjct: 156 AEGSTLEEVSNNCIRLEW--NKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQS 213
Query: 68 VLCVPIWNSNHQIIGVAQVLNRLDGK--PFDDADQRLFEAFVIFCGLGINNTIMYDQVKK 125
+LC+PI N +++GVAQ +N+ G F + D++ F A++ FCG+ ++N +Y+
Sbjct: 214 ILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLL 273
Query: 126 SWAKQSVALDVLS 138
+ V LD+ S
Sbjct: 274 ENKRNQVLLDLAS 286
>gi|61744430 phosphodiesterase 5A isoform 2 [Homo sapiens]
Length = 833
Score = 410 bits (1054), Expect = e-114
Identities = 214/473 (45%), Positives = 310/473 (65%), Gaps = 20/473 (4%)
Query: 15 ESMEKSS------YSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFH---I 65
E +EKSS + IN A+ V +T P+NI D +D RF + + I
Sbjct: 347 EELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCI 406
Query: 66 RSVLCVPIWNSN-HQIIGVAQVLNRLDG-----KPFDDADQRLFEAFVIFCGLGINNTIM 119
RS+LC PI N +++IGV Q++N+++ KPF+ D++ EAFVIFCGLGI NT M
Sbjct: 407 RSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQM 466
Query: 120 YDQVKKSWAKQSVALDVLSYHATCSKAEVDKFK---AANIPLVSELAIDDIHFDDFSLDV 176
Y+ V+++ AKQ V L+VLSYHA+ ++ E + + AA +P L I D F DF L
Sbjct: 467 YEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSD 526
Query: 177 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM-VLYHNWRHAFNVCQLMFAM 235
+RMF +L +VQ F++ +E LCRW+L+V+KNYR V YHNWRHAFN Q MFA
Sbjct: 527 LETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAA 586
Query: 236 LTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFN 295
L Q+ LT++EILA+++ L HDLDHRG NN++ +S LAQLY S +EHHHF+
Sbjct: 587 LKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSI-MEHHHFD 645
Query: 296 HAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 355
+MIL S G+ I + LS +EY ++++KQ+ILATDL LY +RR EFFEL+ K +++
Sbjct: 646 QCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLE 705
Query: 356 IKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDR 415
+ +++F +MLMTACDL A+TKPW I +++AELV +EFF+QGDRER EL + P+ + +R
Sbjct: 706 DPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNR 765
Query: 416 NRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKR 468
+K+++P +Q+ +ID+IC+ LY+AL V+ P+LD NR KW+ L +++
Sbjct: 766 EKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQ 818
Score = 97.4 bits (241), Expect = 3e-20
Identities = 51/133 (38%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Query: 9 AENSFKESMEKSSYS-DWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRS 67
AE S E + + +W N I VA+ G P+NI DAY+DPRF+AE DQI+G+ +S
Sbjct: 166 AEGSTLEEVSNNCIRLEW--NKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQS 223
Query: 68 VLCVPIWNSNHQIIGVAQVLNRLDGK--PFDDADQRLFEAFVIFCGLGINNTIMYDQVKK 125
+LC+PI N +++GVAQ +N+ G F + D++ F A++ FCG+ ++N +Y+
Sbjct: 224 ILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLL 283
Query: 126 SWAKQSVALDVLS 138
+ V LD+ S
Sbjct: 284 ENKRNQVLLDLAS 296
>gi|170650674 phosphodiesterase 6A [Homo sapiens]
Length = 860
Score = 334 bits (857), Expect = 9e-92
Identities = 174/474 (36%), Positives = 269/474 (56%), Gaps = 35/474 (7%)
Query: 25 WLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI--SGFHIRSVLCVPIWNSNHQIIG 82
W + + + VA GL NI +A + F + + + SG+ I++VL +PI N +I+G
Sbjct: 340 WALVSGLPAYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVG 399
Query: 83 VAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHAT 142
VA NR DGKPFD+ D+ L E+ F G + N Y+ + K ++ + D++ YH
Sbjct: 400 VATFYNRKDGKPFDEMDETLMESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVK 459
Query: 143 CSKAEVDKFKA----------------------ANIPLVSELAIDDIHFDDFSLDVDAMI 180
C E+ K A +P + I+ HF D L ++
Sbjct: 460 CDNEEIQKILKTREVYGKEPWECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELV 519
Query: 181 TAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAG 240
++M+ EL +V KF I E L R++ ++ K YR + YHNWRH FNV Q MF++L T
Sbjct: 520 KCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGK 579
Query: 241 FQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMI 300
+ T++E LA++ CHD+DHRGTNN +Q KS + LA+L+G S+ LE HH +
Sbjct: 580 LKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHG-SSILERHHLEFGKTL 638
Query: 301 LQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS-----KGEYDWN 355
L+ E NIF NL+ +++ + ++ +I+ATDL LYF++RT F ++V + E +W
Sbjct: 639 LRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWT 698
Query: 356 -----IKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPS 410
+ ++I +M+MTACDL A+TKPWE+ QVA LV +EF+EQGD ER L+ P
Sbjct: 699 QYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPI 758
Query: 411 AIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL 464
+ DRN+ DELP+LQ+ +ID +C +Y+ + + ++ PMLD + NR +W+ L
Sbjct: 759 PMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKAL 812
>gi|157364939 phosphodiesterase 6C [Homo sapiens]
Length = 858
Score = 329 bits (843), Expect = 4e-90
Identities = 174/475 (36%), Positives = 268/475 (56%), Gaps = 36/475 (7%)
Query: 25 WLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI--SGFHIRSVLCVPIWNSNHQIIG 82
W + + + VA G N+ +A D F + + +G+ I++VL +PI N I+G
Sbjct: 342 WTLISGLPTYVAENGFICNMMNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVG 401
Query: 83 VAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHAT 142
VA NR DGKPFD+ D+ + E F G + NT YD++ K ++ +A ++L
Sbjct: 402 VATFYNRKDGKPFDEHDEYITETLTQFLGWSLLNTDTYDKMNKLENRKDIAQEMLMNQTK 461
Query: 143 CSKAEVDKF----KAANIPLVSELA-------------------IDDIHFDDFSLDVDAM 179
+ E+ + N+ ++ + + + F DF L +
Sbjct: 462 ATPEEIKSILKFQEKLNVDVIDDCEEKQLVAILKEDLPDPRSAELYEFRFSDFPLTEHGL 521
Query: 180 ITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTA 239
I +R+F E+ +V+KFK+ E L RW+ TVRK YR V YHNWRH FNV Q MF +L T
Sbjct: 522 IKCGIRLFFEINVVEKFKVPVEVLTRWMYTVRKGYRAVTYHNWRHGFNVGQTMFTLLMTG 581
Query: 240 GFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVM 299
+ T++E A++ CHD+DHRGTNN +Q KS S LA+L+G S+ LE HH ++
Sbjct: 582 RLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQMKSTSPLARLHG-SSILERHHLEYSKT 640
Query: 300 ILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGE-------- 351
+LQ E NIF NL+ +++ ++ L + +I+ATDL LYF++RT F ++V E
Sbjct: 641 LLQDESLNIFQNLNKRQFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEEA 700
Query: 352 --YDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 409
Y ++I +M+MTACDL A+TKPWE+ QVA +V +EF+EQGD ER L+ P
Sbjct: 701 IKYVTVDPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQP 760
Query: 410 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL 464
+ DRN++DELP+LQ+ +ID +C +Y+ + + ++ PML + NR +W+ L
Sbjct: 761 IPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRFHKEITPMLSGLQNNRVEWKSL 815
>gi|223718037 phosphodiesterase 6B isoform 2 [Homo sapiens]
Length = 853
Score = 326 bits (836), Expect = 3e-89
Identities = 175/478 (36%), Positives = 266/478 (55%), Gaps = 35/478 (7%)
Query: 21 SYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI--SGFHIRSVLCVPIWNSNH 78
S W + + + VA +G NI +A D F + + SG+ I++VL +PI N
Sbjct: 334 SADHWALASGLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKE 393
Query: 79 QIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLS 138
+I+GVA NR DGKPFD+ D+ L E+ F G + NT YD++ K ++ +A D++
Sbjct: 394 EIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVL 453
Query: 139 YHATCSKAEVDKFKAANIPLVSELA----------------------IDDIHFDDFSLDV 176
YH C + E+ L E A I + HF D
Sbjct: 454 YHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTE 513
Query: 177 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAML 236
++ ++M+ ELG+V+KF+I E L R+L ++ K YR + YHNWRH FNV Q MF +L
Sbjct: 514 LDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLL 573
Query: 237 TTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNH 296
T + T++E A++ LCHD+DHRGTNN +Q KS + LA+L+G S+ LE HH
Sbjct: 574 MTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHG-SSILERHHLEF 632
Query: 297 AVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKG------ 350
+L E NI+ NL+ +++ ++ L+ +I+ATDL LYF++R F ++V +
Sbjct: 633 GKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDK 692
Query: 351 ----EYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELK 406
EY ++I +M+MTACDL A+TKPWE+ +VA LV +EF+EQGD ER L
Sbjct: 693 KSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLD 752
Query: 407 LTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL 464
P + DRN+ ELP+LQ+ +ID +C +Y+ + + ++ PM D + NR +W+ L
Sbjct: 753 QQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKAL 810
Score = 45.8 bits (107), Expect = 9e-05
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 35 VASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKP 94
VA T VN+ D + P F + AD+++ + +++L PI N ++ V +N+L+G
Sbjct: 142 VAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGK-DVVAVIMAVNKLNGPF 200
Query: 95 FDDADQRLFEAFVIFCGL 112
F D+ +F ++ F L
Sbjct: 201 FTSEDEDVFLKYLNFATL 218
>gi|223718019 phosphodiesterase 6B isoform 3 [Homo sapiens]
Length = 575
Score = 326 bits (836), Expect = 3e-89
Identities = 175/478 (36%), Positives = 266/478 (55%), Gaps = 35/478 (7%)
Query: 21 SYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI--SGFHIRSVLCVPIWNSNH 78
S W + + + VA +G NI +A D F + + SG+ I++VL +PI N
Sbjct: 55 SADHWALASGLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKE 114
Query: 79 QIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLS 138
+I+GVA NR DGKPFD+ D+ L E+ F G + NT YD++ K ++ +A D++
Sbjct: 115 EIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVL 174
Query: 139 YHATCSKAEVDKFKAANIPLVSELA----------------------IDDIHFDDFSLDV 176
YH C + E+ L E A I + HF D
Sbjct: 175 YHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTE 234
Query: 177 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAML 236
++ ++M+ ELG+V+KF+I E L R+L ++ K YR + YHNWRH FNV Q MF +L
Sbjct: 235 LDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLL 294
Query: 237 TTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNH 296
T + T++E A++ LCHD+DHRGTNN +Q KS + LA+L+G S+ LE HH
Sbjct: 295 MTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHG-SSILERHHLEF 353
Query: 297 AVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKG------ 350
+L E NI+ NL+ +++ ++ L+ +I+ATDL LYF++R F ++V +
Sbjct: 354 GKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDK 413
Query: 351 ----EYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELK 406
EY ++I +M+MTACDL A+TKPWE+ +VA LV +EF+EQGD ER L
Sbjct: 414 KSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLD 473
Query: 407 LTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL 464
P + DRN+ ELP+LQ+ +ID +C +Y+ + + ++ PM D + NR +W+ L
Sbjct: 474 QQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKAL 531
>gi|105990537 phosphodiesterase 6B isoform 1 [Homo sapiens]
Length = 854
Score = 326 bits (836), Expect = 3e-89
Identities = 175/478 (36%), Positives = 266/478 (55%), Gaps = 35/478 (7%)
Query: 21 SYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQI--SGFHIRSVLCVPIWNSNH 78
S W + + + VA +G NI +A D F + + SG+ I++VL +PI N
Sbjct: 334 SADHWALASGLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKE 393
Query: 79 QIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLS 138
+I+GVA NR DGKPFD+ D+ L E+ F G + NT YD++ K ++ +A D++
Sbjct: 394 EIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVL 453
Query: 139 YHATCSKAEVDKFKAANIPLVSELA----------------------IDDIHFDDFSLDV 176
YH C + E+ L E A I + HF D
Sbjct: 454 YHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTE 513
Query: 177 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAML 236
++ ++M+ ELG+V+KF+I E L R+L ++ K YR + YHNWRH FNV Q MF +L
Sbjct: 514 LDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLL 573
Query: 237 TTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNH 296
T + T++E A++ LCHD+DHRGTNN +Q KS + LA+L+G S+ LE HH
Sbjct: 574 MTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHG-SSILERHHLEF 632
Query: 297 AVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKG------ 350
+L E NI+ NL+ +++ ++ L+ +I+ATDL LYF++R F ++V +
Sbjct: 633 GKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDK 692
Query: 351 ----EYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELK 406
EY ++I +M+MTACDL A+TKPWE+ +VA LV +EF+EQGD ER L
Sbjct: 693 KSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLD 752
Query: 407 LTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL 464
P + DRN+ ELP+LQ+ +ID +C +Y+ + + ++ PM D + NR +W+ L
Sbjct: 753 QQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKAL 810
Score = 45.8 bits (107), Expect = 9e-05
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 35 VASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKP 94
VA T VN+ D + P F + AD+++ + +++L PI N ++ V +N+L+G
Sbjct: 142 VAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGK-DVVAVIMAVNKLNGPF 200
Query: 95 FDDADQRLFEAFVIFCGL 112
F D+ +F ++ F L
Sbjct: 201 FTSEDEDVFLKYLNFATL 218
>gi|5729972 phosphodiesterase 10A isoform 2 [Homo sapiens]
Length = 779
Score = 319 bits (817), Expect = 4e-87
Identities = 175/479 (36%), Positives = 277/479 (57%), Gaps = 9/479 (1%)
Query: 10 ENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVL 69
E K +K+ + I IA VA TG +NI DAY DPRF+ E D +G+ R++L
Sbjct: 309 EKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNIL 368
Query: 70 CVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAK 129
C+PI S +IGV Q++N++ G F D+ F+ F +FC L ++ MY +++ S
Sbjct: 369 CMPIV-SRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECI 427
Query: 130 QSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFME 189
V ++ LSYH+ C+ E +P+ I+ HFD + + + ++M
Sbjct: 428 YRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFE---NMWPGIFVYMV 484
Query: 190 LGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVE 249
+ E LCR++++V+KNYR V YHNW+HA V M+A+L + T++E
Sbjct: 485 HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLE 542
Query: 250 ILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIF 309
+++ CLCHDLDHRG +N++ K LA LY TS T+E HHF+ V ILQ EGHNIF
Sbjct: 543 RKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTS-TMEQHHFSQTVSILQLEGHNIF 601
Query: 310 ANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMT 369
+ LSS EY ++++++++I+ATDL LYF R + E+ G + N ++HRD ++MT
Sbjct: 602 STLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMT 661
Query: 370 ACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWI 429
ACDL +VTK W +++ A + +EF+ +GD E +L + P + DR++KDE+P+ QL +
Sbjct: 662 ACDLCSVTKLWPVTKLTANDIYAEFWAEGD-EMKKLGIQPIPMMDRDKKDEVPQGQLGFY 720
Query: 430 DSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASS-SPASVMVAKED 487
+++ +P Y L ++ +P+L + N S+WE++ + A+ SS S A A ED
Sbjct: 721 NAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED 779
Score = 37.4 bits (85), Expect = 0.031
Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 30 SIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNR 89
+++ VA + + + D D RF SG I+SVLC+PI + +IG+ ++
Sbjct: 150 TVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRH 209
Query: 90 LDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVL 137
+ F + Q + A + + + I+ QV + AKQ+ D L
Sbjct: 210 WGKEAFCLSHQEVATANLAWASVAIHQV----QVCRGLAKQTELNDFL 253
>gi|194595488 phosphodiesterase 10A isoform 1 [Homo sapiens]
Length = 789
Score = 319 bits (817), Expect = 4e-87
Identities = 175/479 (36%), Positives = 277/479 (57%), Gaps = 9/479 (1%)
Query: 10 ENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVL 69
E K +K+ + I IA VA TG +NI DAY DPRF+ E D +G+ R++L
Sbjct: 319 EKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNIL 378
Query: 70 CVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAK 129
C+PI S +IGV Q++N++ G F D+ F+ F +FC L ++ MY +++ S
Sbjct: 379 CMPIV-SRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECI 437
Query: 130 QSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFME 189
V ++ LSYH+ C+ E +P+ I+ HFD + + + ++M
Sbjct: 438 YRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFE---NMWPGIFVYMV 494
Query: 190 LGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVE 249
+ E LCR++++V+KNYR V YHNW+HA V M+A+L + T++E
Sbjct: 495 HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN--HTLFTDLE 552
Query: 250 ILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIF 309
+++ CLCHDLDHRG +N++ K LA LY TS T+E HHF+ V ILQ EGHNIF
Sbjct: 553 RKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTS-TMEQHHFSQTVSILQLEGHNIF 611
Query: 310 ANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMT 369
+ LSS EY ++++++++I+ATDL LYF R + E+ G + N ++HRD ++MT
Sbjct: 612 STLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMT 671
Query: 370 ACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWI 429
ACDL +VTK W +++ A + +EF+ +GD E +L + P + DR++KDE+P+ QL +
Sbjct: 672 ACDLCSVTKLWPVTKLTANDIYAEFWAEGD-EMKKLGIQPIPMMDRDKKDEVPQGQLGFY 730
Query: 430 DSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASS-SPASVMVAKED 487
+++ +P Y L ++ +P+L + N S+WE++ + A+ SS S A A ED
Sbjct: 731 NAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED 789
Score = 37.4 bits (85), Expect = 0.031
Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 30 SIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNR 89
+++ VA + + + D D RF SG I+SVLC+PI + +IG+ ++
Sbjct: 160 TVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRH 219
Query: 90 LDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVL 137
+ F + Q + A + + + I+ QV + AKQ+ D L
Sbjct: 220 WGKEAFCLSHQEVATANLAWASVAIHQV----QVCRGLAKQTELNDFL 263
>gi|226246591 phosphodiesterase 2A isoform 3 [Homo sapiens]
Length = 932
Score = 303 bits (776), Expect = 2e-82
Identities = 167/456 (36%), Positives = 257/456 (56%), Gaps = 12/456 (2%)
Query: 28 NNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVL 87
+ IA VA+TG +NI DAY P F D +GF R++LC PI N N ++IGVA+++
Sbjct: 453 DQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELV 512
Query: 88 NRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAE 147
N+++G F D+ L AF I+CG+ I ++++Y +V ++ + +A +++ YH S E
Sbjct: 513 NKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDE 572
Query: 148 VDKFKAANIPLVSELAIDDIHFDDF-----SLDVDAMITAALRMFMELGMVQKFKIDYET 202
K I V+ + D +F F SL D A L M ++ + +KID T
Sbjct: 573 YTKLLHDGIQPVAAI---DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPT 629
Query: 203 LCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDL 262
L R+ L V+K YR YHNW HAF+V + + + L ++EI A+ + C+CHDL
Sbjct: 630 LARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDL 689
Query: 263 DHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLM 321
DHRGTNN+FQ S S LA LY + + +E HHF A+ IL + G NIF + S K+Y ++
Sbjct: 690 DHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRML 749
Query: 322 QLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWE 381
L++ ILATDL + + ++ G YD N K H + +LMT+CDL TK W+
Sbjct: 750 DLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWK 808
Query: 382 ISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALV 441
+R++AEL+ EFF QGD E+ + P + DR K +P LQ+ +++ I MP+Y+ L
Sbjct: 809 TTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDR-EKAYIPELQISFMEHIAMPIYKLLQ 866
Query: 442 KVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS 477
+ K + + VA+NR W ++ K + S++
Sbjct: 867 DLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 902
Score = 35.0 bits (79), Expect = 0.15
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 62 GFHIRSVLCVPIWN-SNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
G ++++LCVP+ + + Q++ +A N+L+G F D D+ + + + + +T+ +
Sbjct: 315 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 374
Query: 121 DQVKK 125
+ +K
Sbjct: 375 QKEQK 379
>gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens]
Length = 934
Score = 303 bits (776), Expect = 2e-82
Identities = 167/456 (36%), Positives = 257/456 (56%), Gaps = 12/456 (2%)
Query: 28 NNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVL 87
+ IA VA+TG +NI DAY P F D +GF R++LC PI N N ++IGVA+++
Sbjct: 455 DQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELV 514
Query: 88 NRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAE 147
N+++G F D+ L AF I+CG+ I ++++Y +V ++ + +A +++ YH S E
Sbjct: 515 NKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDE 574
Query: 148 VDKFKAANIPLVSELAIDDIHFDDF-----SLDVDAMITAALRMFMELGMVQKFKIDYET 202
K I V+ + D +F F SL D A L M ++ + +KID T
Sbjct: 575 YTKLLHDGIQPVAAI---DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPT 631
Query: 203 LCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDL 262
L R+ L V+K YR YHNW HAF+V + + + L ++EI A+ + C+CHDL
Sbjct: 632 LARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDL 691
Query: 263 DHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLM 321
DHRGTNN+FQ S S LA LY + + +E HHF A+ IL + G NIF + S K+Y ++
Sbjct: 692 DHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRML 751
Query: 322 QLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWE 381
L++ ILATDL + + ++ G YD N K H + +LMT+CDL TK W+
Sbjct: 752 DLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWK 810
Query: 382 ISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALV 441
+R++AEL+ EFF QGD E+ + P + DR K +P LQ+ +++ I MP+Y+ L
Sbjct: 811 TTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDR-EKAYIPELQISFMEHIAMPIYKLLQ 868
Query: 442 KVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS 477
+ K + + VA+NR W ++ K + S++
Sbjct: 869 DLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 904
Score = 35.0 bits (79), Expect = 0.15
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 62 GFHIRSVLCVPIWN-SNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
G ++++LCVP+ + + Q++ +A N+L+G F D D+ + + + + +T+ +
Sbjct: 317 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 376
Query: 121 DQVKK 125
+ +K
Sbjct: 377 QKEQK 381
>gi|4505657 phosphodiesterase 2A isoform 1 [Homo sapiens]
Length = 941
Score = 303 bits (776), Expect = 2e-82
Identities = 167/456 (36%), Positives = 257/456 (56%), Gaps = 12/456 (2%)
Query: 28 NNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVL 87
+ IA VA+TG +NI DAY P F D +GF R++LC PI N N ++IGVA+++
Sbjct: 462 DQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELV 521
Query: 88 NRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAE 147
N+++G F D+ L AF I+CG+ I ++++Y +V ++ + +A +++ YH S E
Sbjct: 522 NKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDE 581
Query: 148 VDKFKAANIPLVSELAIDDIHFDDF-----SLDVDAMITAALRMFMELGMVQKFKIDYET 202
K I V+ + D +F F SL D A L M ++ + +KID T
Sbjct: 582 YTKLLHDGIQPVAAI---DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPT 638
Query: 203 LCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDL 262
L R+ L V+K YR YHNW HAF+V + + + L ++EI A+ + C+CHDL
Sbjct: 639 LARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDL 698
Query: 263 DHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLM 321
DHRGTNN+FQ S S LA LY + + +E HHF A+ IL + G NIF + S K+Y ++
Sbjct: 699 DHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRML 758
Query: 322 QLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWE 381
L++ ILATDL + + ++ G YD N K H + +LMT+CDL TK W+
Sbjct: 759 DLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWK 817
Query: 382 ISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALV 441
+R++AEL+ EFF QGD E+ + P + DR K +P LQ+ +++ I MP+Y+ L
Sbjct: 818 TTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDR-EKAYIPELQISFMEHIAMPIYKLLQ 875
Query: 442 KVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS 477
+ K + + VA+NR W ++ K + S++
Sbjct: 876 DLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 911
Score = 35.0 bits (79), Expect = 0.15
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 62 GFHIRSVLCVPIWN-SNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120
G ++++LCVP+ + + Q++ +A N+L+G F D D+ + + + + +T+ +
Sbjct: 324 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 383
Query: 121 DQVKK 125
+ +K
Sbjct: 384 QKEQK 388
>gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]
Length = 386
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 54 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 113
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 114 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 173
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 174 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 233
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 234 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 290
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 291 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]
Length = 386
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 54 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 113
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 114 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 173
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 174 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 233
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 234 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 290
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 291 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]
Length = 567
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 235 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 294
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 295 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 354
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 355 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 414
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 415 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 471
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 472 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 527
>gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]
Length = 552
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 220 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 279
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 280 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 339
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 340 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 399
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 400 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 456
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 457 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 512
>gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]
Length = 526
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 194 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 253
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 254 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 313
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 314 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 373
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 374 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 430
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 431 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 486
>gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]
Length = 376
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 44 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 103
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 104 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 163
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 164 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 223
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 224 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 280
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 281 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 336
>gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]
Length = 386
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 54 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 113
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 114 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 173
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 174 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 233
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 234 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 290
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 291 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]
Length = 491
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 159 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 218
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 219 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 278
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 279 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 338
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 339 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 395
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 396 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 451
>gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]
Length = 459
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 127 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 186
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 187 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 246
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 247 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 306
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 307 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 363
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 364 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 419
>gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]
Length = 376
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 44 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 103
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 104 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 163
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 164 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 223
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 224 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 280
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 281 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 336
>gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]
Length = 433
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 101 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 160
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 161 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 220
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 221 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 280
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 281 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 337
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 338 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 393
>gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]
Length = 507
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 175 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 234
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 235 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 294
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 295 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 354
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 355 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 411
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 412 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 467
>gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]
Length = 386
Score = 159 bits (401), Expect = 7e-39
Identities = 90/297 (30%), Positives = 161/297 (54%), Gaps = 5/297 (1%)
Query: 169 FDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNV 228
FD + + + M++ M+ +LG+V+ F I+ TL RWL V NYR +HN+RH F V
Sbjct: 54 FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCV 113
Query: 229 CQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT 288
Q+M++M+ Q+ ++ +IL ++ +CHDLDH G NN +Q + + LA Y +
Sbjct: 114 AQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISP 173
Query: 289 LEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVS 348
LE+HH A IL NIF+N+ + + Q + ILATD+ + E F E +
Sbjct: 174 LENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME 233
Query: 349 KGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLT 408
+D++ + H + + +L+ CD+ +P E++ + + E+F Q DRE+ E L
Sbjct: 234 --NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE-GLP 290
Query: 409 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKP-MLDSVATNRSKWEEL 464
+ DR++ + Q+ +I + +P+++ + K+ ++ ML + +R ++EEL
Sbjct: 291 VAPFMDRDKVTK-ATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,014,425
Number of Sequences: 37866
Number of extensions: 613917
Number of successful extensions: 1615
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1383
Number of HSP's gapped (non-prelim): 101
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.