BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116256329 membrane metallo-endopeptidase [Homo sapiens] (750 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 1524 0.0 gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 1524 0.0 gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 1524 0.0 gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 1524 0.0 gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] 832 0.0 gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapi... 541 e-153 gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapi... 541 e-153 gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapi... 541 e-153 gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] 541 e-153 gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 487 e-137 gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 487 e-137 gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 487 e-137 gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi... 487 e-137 gi|90403592 phosphate-regulating neutral endopeptidase [Homo sap... 480 e-135 gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] 443 e-124 gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] 216 6e-56 gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 34 0.44 gi|157364974 sucrase-isomaltase [Homo sapiens] 34 0.44 gi|221316699 maltase-glucoamylase [Homo sapiens] 34 0.57 gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 34 0.57 gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 34 0.57 gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 34 0.57 gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 34 0.57 gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 34 0.57 gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 34 0.57 gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ... 33 0.74 gi|139948432 adlican [Homo sapiens] 33 0.74 gi|4758104 cytochrome P450, family 7, subfamily B, polypeptide 1... 33 0.97 gi|14043022 methionyl-tRNA synthetase [Homo sapiens] 33 0.97 gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 33 1.3 >gi|116256333 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 1524 bits (3946), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS Sbjct: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 Query: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD Sbjct: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 Query: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA Sbjct: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 Query: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE Sbjct: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 Query: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY Sbjct: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 Query: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT Sbjct: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 Query: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME Sbjct: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 Query: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI Sbjct: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 Query: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA Sbjct: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 Query: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD Sbjct: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 Query: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR Sbjct: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 Query: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII Sbjct: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 Query: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW Sbjct: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 >gi|116256331 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 1524 bits (3946), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS Sbjct: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 Query: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD Sbjct: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 Query: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA Sbjct: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 Query: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE Sbjct: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 Query: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY Sbjct: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 Query: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT Sbjct: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 Query: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME Sbjct: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 Query: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI Sbjct: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 Query: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA Sbjct: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 Query: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD Sbjct: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 Query: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR Sbjct: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 Query: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII Sbjct: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 Query: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW Sbjct: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 >gi|116256327 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 1524 bits (3946), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS Sbjct: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 Query: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD Sbjct: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 Query: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA Sbjct: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 Query: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE Sbjct: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 Query: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY Sbjct: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 Query: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT Sbjct: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 Query: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME Sbjct: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 Query: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI Sbjct: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 Query: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA Sbjct: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 Query: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD Sbjct: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 Query: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR Sbjct: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 Query: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII Sbjct: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 Query: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW Sbjct: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 >gi|116256329 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 1524 bits (3946), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS Sbjct: 1 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS 60 Query: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD Sbjct: 61 DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD 120 Query: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA Sbjct: 121 VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA 180 Query: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE Sbjct: 181 SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE 240 Query: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY Sbjct: 241 ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY 300 Query: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT Sbjct: 301 NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT 360 Query: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME Sbjct: 361 KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME 420 Query: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI Sbjct: 421 NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI 480 Query: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA Sbjct: 481 GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 Query: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD Sbjct: 541 VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD 600 Query: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR Sbjct: 601 GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR 660 Query: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII Sbjct: 661 AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII 720 Query: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW Sbjct: 721 GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 >gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] Length = 779 Score = 832 bits (2149), Expect = 0.0 Identities = 382/696 (54%), Positives = 529/696 (76%), Gaps = 5/696 (0%) Query: 56 ICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELE 115 +C + C+ +AAR++QNMD TTEPC DF+++ACGGWL+R+VIPET+SRY FD+LRDELE Sbjct: 88 VCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELE 147 Query: 116 VVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWE 175 V+LK VL+ +D AV+KA+ LYRSC+N+S I+ RG +PLL +L + GWPVA + W Sbjct: 148 VILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWN 207 Query: 176 QKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECT 235 + G W E+ +A +NS++ ++VLI+LF+ DD+NS H+I+IDQP LG+PSR+YY Sbjct: 208 ETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNG 267 Query: 236 GIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRND 295 G ++ AY+ FM+SVA L+R++ LP D + +M +V+ELE ++A AT E+R+D Sbjct: 268 GSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHD 327 Query: 296 PMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKL 355 + LY++M L ++Q+ F L K F+W F ++S+V I + +E+VVVY YL L Sbjct: 328 VIALYHRMGLEELQSQFGL----KGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383 Query: 356 KPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYV 415 + I+ YSAR +QN + WR ++D + SLS+ +K++R +RKAL+GT E WR C YV Sbjct: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYV 443 Query: 416 NGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALA 475 N NMENAVG LYV AF G+SK +V +LI ++R VF++TLD+L WMD E+KK+A+EKA++ Sbjct: 444 NSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMS 503 Query: 476 IKERIGYPDDIVSNDNK-LNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE 534 I+E+IG+PD I+ N+ L+ EY LN+ ED YFEN +QNLK + L+KLREKVD + Sbjct: 504 IREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNL 563 Query: 535 WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNG 594 WI GAAVVNAFYS RNQIVFPAGILQPPFFS +Q +LN+GGIGMVIGHEITHGFDDNG Sbjct: 564 WIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNG 623 Query: 595 RNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGG 654 RNF+K+G+++DWW+ S +F+EQS+CM+YQYGN+SWDLA Q++NG NTLGENIADNGG Sbjct: 624 RNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGG 683 Query: 655 LGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSP 714 + QAY+AY ++ + G+++ LPGLDL H+QLFF+N+AQVWCG+YRPE+A+ SIKTDVHSP Sbjct: 684 VRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSP 743 Query: 715 GNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 +R++G+LQN A F++ FHC + + M+P+++CRVW Sbjct: 744 LKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779 >gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapiens] Length = 767 Score = 541 bits (1393), Expect = e-153 Identities = 290/747 (38%), Positives = 429/747 (57%), Gaps = 32/747 (4%) Query: 13 INTPKPKKKQR-W---TPLEISLSVLVLLLTIIAVTMIAL----YATYDDGICKSSDCIK 64 +N P+ QR W T +E L VLV+LL V +A Y T +C S C+ Sbjct: 44 VNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVS 103 Query: 65 SAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQE 124 + ++ +MD T +PC DFF YACGGW+K N +P+ SR+G F L + + ++K +L+ Sbjct: 104 VTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN 163 Query: 125 PKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTA 184 A +KA+ YR+C+NE+ I+ +PL++L+ + GW + T W A Sbjct: 164 STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI-TGPW-----AKDNF 217 Query: 185 EKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTA 244 + + + + Y +++V D KNS ++VI +DQ LGLPSRDYY ++ T Sbjct: 218 QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTG 277 Query: 245 YVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMT 304 Y+++M+ + +L+ DE + +M ++++ E +AN T E R D L+Y+K+T Sbjct: 278 YLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVT 332 Query: 305 LAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSA 364 A++Q +WL F N I V I+ E +VVY EYL ++ ++ Sbjct: 333 AAELQTL------APAINWLPFLNTIFYPVEIN--ESEPIVVYDKEYLEQISTLINTTDR 384 Query: 365 RDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAV 423 L N M W + S L + ++++ F + +YGT W+ C + N+ A+ Sbjct: 385 CLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFAL 444 Query: 424 GRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYP 483 G ++V+A FA +SK + ++I +I++ F ++L L WMD ET+K A+EKA AI IGYP Sbjct: 445 GPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYP 504 Query: 484 DDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVN 543 + I+ + +L+ + + D YFEN ++ FS +LR+ ++D+W +VN Sbjct: 505 NFIM-DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVN 563 Query: 544 AFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDL 603 A+YS +N+IVFPAGILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++KDG+L Sbjct: 564 AYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNL 623 Query: 604 VDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQ 663 WW S FK Q++CMV QY N+S G+ +NG +TLGENIADNGGL AYRAYQ Sbjct: 624 RPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRHTLGENIADNGGLKAAYRAYQ 680 Query: 664 NYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTL 723 N++KKNG E LP L L + QLFFL FAQVWC PE + + TD HSP FR+IG+L Sbjct: 681 NWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSL 740 Query: 724 QNSAEFSEAFHCRKNSYMNPEKKCRVW 750 NS EFSE F C S MNP KC VW Sbjct: 741 SNSKEFSEHFRCPPGSPMNPPHKCEVW 767 >gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapiens] Length = 754 Score = 541 bits (1393), Expect = e-153 Identities = 290/747 (38%), Positives = 429/747 (57%), Gaps = 32/747 (4%) Query: 13 INTPKPKKKQR-W---TPLEISLSVLVLLLTIIAVTMIAL----YATYDDGICKSSDCIK 64 +N P+ QR W T +E L VLV+LL V +A Y T +C S C+ Sbjct: 31 VNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVS 90 Query: 65 SAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQE 124 + ++ +MD T +PC DFF YACGGW+K N +P+ SR+G F L + + ++K +L+ Sbjct: 91 VTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN 150 Query: 125 PKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTA 184 A +KA+ YR+C+NE+ I+ +PL++L+ + GW + T W A Sbjct: 151 STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI-TGPW-----AKDNF 204 Query: 185 EKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTA 244 + + + + Y +++V D KNS ++VI +DQ LGLPSRDYY ++ T Sbjct: 205 QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTG 264 Query: 245 YVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMT 304 Y+++M+ + +L+ DE + +M ++++ E +AN T E R D L+Y+K+T Sbjct: 265 YLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVT 319 Query: 305 LAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSA 364 A++Q +WL F N I V I+ E +VVY EYL ++ ++ Sbjct: 320 AAELQTL------APAINWLPFLNTIFYPVEIN--ESEPIVVYDKEYLEQISTLINTTDR 371 Query: 365 RDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAV 423 L N M W + S L + ++++ F + +YGT W+ C + N+ A+ Sbjct: 372 CLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFAL 431 Query: 424 GRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYP 483 G ++V+A FA +SK + ++I +I++ F ++L L WMD ET+K A+EKA AI IGYP Sbjct: 432 GPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYP 491 Query: 484 DDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVN 543 + I+ + +L+ + + D YFEN ++ FS +LR+ ++D+W +VN Sbjct: 492 NFIM-DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVN 550 Query: 544 AFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDL 603 A+YS +N+IVFPAGILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++KDG+L Sbjct: 551 AYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNL 610 Query: 604 VDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQ 663 WW S FK Q++CMV QY N+S G+ +NG +TLGENIADNGGL AYRAYQ Sbjct: 611 RPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRHTLGENIADNGGLKAAYRAYQ 667 Query: 664 NYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTL 723 N++KKNG E LP L L + QLFFL FAQVWC PE + + TD HSP FR+IG+L Sbjct: 668 NWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSL 727 Query: 724 QNSAEFSEAFHCRKNSYMNPEKKCRVW 750 NS EFSE F C S MNP KC VW Sbjct: 728 SNSKEFSEHFRCPPGSPMNPPHKCEVW 754 >gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapiens] Length = 758 Score = 541 bits (1393), Expect = e-153 Identities = 290/747 (38%), Positives = 429/747 (57%), Gaps = 32/747 (4%) Query: 13 INTPKPKKKQR-W---TPLEISLSVLVLLLTIIAVTMIAL----YATYDDGICKSSDCIK 64 +N P+ QR W T +E L VLV+LL V +A Y T +C S C+ Sbjct: 35 VNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVS 94 Query: 65 SAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQE 124 + ++ +MD T +PC DFF YACGGW+K N +P+ SR+G F L + + ++K +L+ Sbjct: 95 VTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN 154 Query: 125 PKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTA 184 A +KA+ YR+C+NE+ I+ +PL++L+ + GW + T W A Sbjct: 155 STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI-TGPW-----AKDNF 208 Query: 185 EKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTA 244 + + + + Y +++V D KNS ++VI +DQ LGLPSRDYY ++ T Sbjct: 209 QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTG 268 Query: 245 YVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMT 304 Y+++M+ + +L+ DE + +M ++++ E +AN T E R D L+Y+K+T Sbjct: 269 YLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVT 323 Query: 305 LAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSA 364 A++Q +WL F N I V I+ E +VVY EYL ++ ++ Sbjct: 324 AAELQTL------APAINWLPFLNTIFYPVEIN--ESEPIVVYDKEYLEQISTLINTTDR 375 Query: 365 RDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAV 423 L N M W + S L + ++++ F + +YGT W+ C + N+ A+ Sbjct: 376 CLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFAL 435 Query: 424 GRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYP 483 G ++V+A FA +SK + ++I +I++ F ++L L WMD ET+K A+EKA AI IGYP Sbjct: 436 GPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYP 495 Query: 484 DDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVN 543 + I+ + +L+ + + D YFEN ++ FS +LR+ ++D+W +VN Sbjct: 496 NFIM-DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVN 554 Query: 544 AFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDL 603 A+YS +N+IVFPAGILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++KDG+L Sbjct: 555 AYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNL 614 Query: 604 VDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQ 663 WW S FK Q++CMV QY N+S G+ +NG +TLGENIADNGGL AYRAYQ Sbjct: 615 RPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRHTLGENIADNGGLKAAYRAYQ 671 Query: 664 NYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTL 723 N++KKNG E LP L L + QLFFL FAQVWC PE + + TD HSP FR+IG+L Sbjct: 672 NWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSL 731 Query: 724 QNSAEFSEAFHCRKNSYMNPEKKCRVW 750 NS EFSE F C S MNP KC VW Sbjct: 732 SNSKEFSEHFRCPPGSPMNPPHKCEVW 758 >gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] Length = 770 Score = 541 bits (1393), Expect = e-153 Identities = 290/747 (38%), Positives = 429/747 (57%), Gaps = 32/747 (4%) Query: 13 INTPKPKKKQR-W---TPLEISLSVLVLLLTIIAVTMIAL----YATYDDGICKSSDCIK 64 +N P+ QR W T +E L VLV+LL V +A Y T +C S C+ Sbjct: 47 VNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVS 106 Query: 65 SAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQE 124 + ++ +MD T +PC DFF YACGGW+K N +P+ SR+G F L + + ++K +L+ Sbjct: 107 VTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN 166 Query: 125 PKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTA 184 A +KA+ YR+C+NE+ I+ +PL++L+ + GW + T W A Sbjct: 167 STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNI-TGPW-----AKDNF 220 Query: 185 EKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTA 244 + + + + Y +++V D KNS ++VI +DQ LGLPSRDYY ++ T Sbjct: 221 QDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTG 280 Query: 245 YVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMT 304 Y+++M+ + +L+ DE + +M ++++ E +AN T E R D L+Y+K+T Sbjct: 281 YLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVT 335 Query: 305 LAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSA 364 A++Q +WL F N I V I+ E +VVY EYL ++ ++ Sbjct: 336 AAELQTL------APAINWLPFLNTIFYPVEIN--ESEPIVVYDKEYLEQISTLINTTDR 387 Query: 365 RDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAV 423 L N M W + S L + ++++ F + +YGT W+ C + N+ A+ Sbjct: 388 CLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFAL 447 Query: 424 GRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYP 483 G ++V+A FA +SK + ++I +I++ F ++L L WMD ET+K A+EKA AI IGYP Sbjct: 448 GPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYP 507 Query: 484 DDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVN 543 + I+ + +L+ + + D YFEN ++ FS +LR+ ++D+W +VN Sbjct: 508 NFIM-DPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVN 566 Query: 544 AFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDL 603 A+YS +N+IVFPAGILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++KDG+L Sbjct: 567 AYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNL 626 Query: 604 VDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQ 663 WW S FK Q++CMV QY N+S G+ +NG +TLGENIADNGGL AYRAYQ Sbjct: 627 RPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRHTLGENIADNGGLKAAYRAYQ 683 Query: 664 NYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTL 723 N++KKNG E LP L L + QLFFL FAQVWC PE + + TD HSP FR+IG+L Sbjct: 684 NWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSL 743 Query: 724 QNSAEFSEAFHCRKNSYMNPEKKCRVW 750 NS EFSE F C S MNP KC VW Sbjct: 744 SNSKEFSEHFRCPPGSPMNPPHKCEVW 770 >gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapiens] Length = 765 Score = 487 bits (1254), Expect = e-137 Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%) Query: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79 T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P Sbjct: 57 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 116 Query: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138 C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK + Sbjct: 117 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 176 Query: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198 Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y Sbjct: 177 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 230 Query: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258 +++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+ Sbjct: 231 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 290 Query: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318 P + +M +V+ELE ++AN T + R D +Y+KM+++++Q Sbjct: 291 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 338 Query: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378 WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W + Sbjct: 339 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 396 Query: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437 SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK Sbjct: 397 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 456 Query: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497 + E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y Sbjct: 457 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 515 Query: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557 ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA Sbjct: 516 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 575 Query: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617 GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+ Sbjct: 576 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 635 Query: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677 + CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP Sbjct: 636 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 692 Query: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737 + L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C Sbjct: 693 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 752 Query: 738 NSYMNPEKKCRVW 750 S MNP + C VW Sbjct: 753 GSPMNPGQLCEVW 765 >gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapiens] Length = 811 Score = 487 bits (1254), Expect = e-137 Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%) Query: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79 T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P Sbjct: 103 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 162 Query: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138 C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK + Sbjct: 163 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 222 Query: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198 Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y Sbjct: 223 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 276 Query: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258 +++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+ Sbjct: 277 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 336 Query: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318 P + +M +V+ELE ++AN T + R D +Y+KM+++++Q Sbjct: 337 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 384 Query: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378 WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W + Sbjct: 385 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 442 Query: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437 SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK Sbjct: 443 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 502 Query: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497 + E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y Sbjct: 503 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 561 Query: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557 ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA Sbjct: 562 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 621 Query: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617 GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+ Sbjct: 622 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 681 Query: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677 + CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP Sbjct: 682 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 738 Query: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737 + L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C Sbjct: 739 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 798 Query: 738 NSYMNPEKKCRVW 750 S MNP + C VW Sbjct: 799 GSPMNPGQLCEVW 811 >gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] Length = 736 Score = 487 bits (1254), Expect = e-137 Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%) Query: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79 T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P Sbjct: 28 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 87 Query: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138 C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK + Sbjct: 88 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 147 Query: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198 Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y Sbjct: 148 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 201 Query: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258 +++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+ Sbjct: 202 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 261 Query: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318 P + +M +V+ELE ++AN T + R D +Y+KM+++++Q Sbjct: 262 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 309 Query: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378 WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W + Sbjct: 310 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 367 Query: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437 SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK Sbjct: 368 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 427 Query: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497 + E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y Sbjct: 428 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 486 Query: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557 ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA Sbjct: 487 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 546 Query: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617 GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+ Sbjct: 547 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 606 Query: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677 + CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP Sbjct: 607 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 663 Query: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737 + L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C Sbjct: 664 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 723 Query: 738 NSYMNPEKKCRVW 750 S MNP + C VW Sbjct: 724 GSPMNPGQLCEVW 736 >gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapiens] Length = 883 Score = 487 bits (1254), Expect = e-137 Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%) Query: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79 T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P Sbjct: 175 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 234 Query: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138 C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK + Sbjct: 235 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 294 Query: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198 Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y Sbjct: 295 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 348 Query: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258 +++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+ Sbjct: 349 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 408 Query: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318 P + +M +V+ELE ++AN T + R D +Y+KM+++++Q Sbjct: 409 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 456 Query: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378 WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W + Sbjct: 457 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 514 Query: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437 SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK Sbjct: 515 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 574 Query: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497 + E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y Sbjct: 575 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 633 Query: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557 ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA Sbjct: 634 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 693 Query: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617 GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+ Sbjct: 694 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 753 Query: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677 + CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP Sbjct: 754 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 810 Query: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737 + L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C Sbjct: 811 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 870 Query: 738 NSYMNPEKKCRVW 750 S MNP + C VW Sbjct: 871 GSPMNPGQLCEVW 883 >gi|90403592 phosphate-regulating neutral endopeptidase [Homo sapiens] Length = 749 Score = 480 bits (1236), Expect = e-135 Identities = 265/738 (35%), Positives = 417/738 (56%), Gaps = 40/738 (5%) Query: 33 VLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWL 92 VL +L +++ +++L A + C +CI++AA ++ ++ + +PC +FF++AC GW+ Sbjct: 32 VLGTILFLVSQGLLSLQAKQE--YCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWI 89 Query: 93 KRNVIPETSSRYGNFDILRDELEVVLKDVLQEP--KTEDIVAVQKAKALYRSCINESAID 150 N IPE YG + LR +++ LK++L++ + D A+QKAK LY SC+NE AI+ Sbjct: 90 SNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIE 149 Query: 151 SRGGEPLLKLLPDI-YGWPVATEN------WEQKYGASWTAEKAIAQLNSKYGKKVLINL 203 +PLL +L + WPV N W ++ ++ + +A +Y V I L Sbjct: 150 KADAKPLLHILRHSPFRWPVLESNIGPEGVWSER---KFSLLQTLATFRGQYSNSVFIRL 206 Query: 204 FVGTDDKNSVNHVIHIDQPRLGLPSR-DYYECTGIYKEACTAYVDFMISVARLIRQEERL 262 +V DDK S H++ +DQ L L R DY + + K A FM+ A L L Sbjct: 207 YVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVL------L 260 Query: 263 PIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFS 322 + ++ +M V+ LE +IA E+R + YNKM ++++ F Sbjct: 261 GANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAM-YNKMNISELSAMIP------QFD 313 Query: 323 WLNFTNEIMSTVNI----SITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378 WL + +++ T I+ E+VVV P+Y L IL + + N + WR + Sbjct: 314 WLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYS 373 Query: 379 LVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKH 438 + +LSR ++ F + + GTT+ W +C N++ + VG+++V+ F + K Sbjct: 374 RIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKE 433 Query: 439 VVEDLIAQIREVFIQTLD-DLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497 ++E+L+ +R FI L+ + WMDA TK++A+EKA A+ ++GYP+ I+ ND +N + Sbjct: 434 MMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIM-NDTHVNEDL 492 Query: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557 + + E +YF N++Q K+ LR+ V K EW + VNAFYS+ NQI FPA Sbjct: 493 KAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPA 552 Query: 558 GILQPPFF-SAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFK 616 G LQ PFF + SL+YG IG+++GHE THGFD+NGR ++K+G+L WW+ +S FK Sbjct: 553 GELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFK 612 Query: 617 EQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYI---KKNGEEK 673 E+++CM+ QY N+ W A G ++ G TLGENIADNGGL +A+RAY+ +I ++ EE Sbjct: 613 EKTKCMINQYSNYYWKKA-GLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEP 671 Query: 674 LLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAF 733 LLPG+ + QLFFL++A V C +YRPE A ++ HSP FR+ G + N EF +AF Sbjct: 672 LLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAF 731 Query: 734 HCRKNSYMN-PEKKCRVW 750 +C NS MN CR+W Sbjct: 732 NCPPNSTMNRGMDSCRLW 749 >gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] Length = 775 Score = 443 bits (1140), Expect = e-124 Identities = 257/744 (34%), Positives = 390/744 (52%), Gaps = 38/744 (5%) Query: 23 RWTPLEISL-SVLVLLLTIIAVTMIALYATYDDGI----------CKSSDCIKSAAR-LI 70 RW E+ L S LV + A+ L Y + C AAR L Sbjct: 54 RWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLA 113 Query: 71 QNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDI 130 N+DA+ +PC DF+ +ACGGWL+R+ IP+ YG + ++ E L+ +L P Sbjct: 114 ANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPG 173 Query: 131 VAVQ-KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIA 189 A Q K +A +RSC++ I+ G P+L+++ D GW + A W + + Sbjct: 174 GAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLY 233 Query: 190 QLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEAC-TAYVDF 248 + Y L +L V DD+NS +VI IDQ L LP R Y E AY F Sbjct: 234 KAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVF 293 Query: 249 MISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED--RNDPMLLYNKMTLA 306 M V L+ + + + +++++E+++AN T D R D +YNK+TL Sbjct: 294 MERVLSLLGADA--------VEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLG 345 Query: 307 QIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARD 366 Q+Q W ++I + EE+VV+ A +Y+ ++ ++ R Sbjct: 346 QLQKITP------HLRWKWLLDQIFQE---DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396 Query: 367 LQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRL 426 L N + WR ++ L LS ++E+ + + + G+ R C N + A+G L Sbjct: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGAL 456 Query: 427 YVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDI 486 +V F+ SK V+ L+ I+ + Q L++L WMDAET+ A K + +GYPD + Sbjct: 457 FVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFL 516 Query: 487 VSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFY 546 + D ++ EY E E YF+NI+ +++FS +KK+R++VDK W+ +NA+Y Sbjct: 517 LKPD-AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574 Query: 547 SSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDW 606 +NQ+VFPAGILQP + SLNYGGIG +IGHE+THG+DD G +++ G+L+ W Sbjct: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634 Query: 607 WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYI 666 WT+ S S F +++C+V Y NF+ Q +NG +TLGENIAD GGL AY AYQ ++ Sbjct: 635 WTEASYSRFLRKAECIVRLYDNFT---VYNQRVNGKHTLGENIADMGGLKLAYHAYQKWV 691 Query: 667 KKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726 +++G E LP L H QLFF+ FAQ WC R + + TD H+P ++R++G++ Sbjct: 692 REHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQF 751 Query: 727 AEFSEAFHCRKNSYMNPEKKCRVW 750 EF AFHC K+S MNP KC VW Sbjct: 752 EEFGRAFHCPKDSPMNPAHKCSVW 775 >gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] Length = 732 Score = 216 bits (550), Expect = 6e-56 Identities = 173/749 (23%), Positives = 332/749 (44%), Gaps = 80/749 (10%) Query: 24 WTPLEISLSVLVLLLTIIAVTMIALYATYDDGI--CKSSDCIKSAARLIQNMDATTEPCT 81 W L+ +++L ++ +++ Y + G C++S C+ + + + + PCT Sbjct: 42 WAVARRVLTAILILGLLLCFSVLLFYNFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCT 101 Query: 82 DFFKYACGGWLK-RNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALY 140 DFF +ACG + N E +++ N + LR LEV + +KA Y Sbjct: 102 DFFSFACGRAKETNNSFQELATK--NKNRLRRILEV-------QNSWHPGSGEEKAFQFY 152 Query: 141 RSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTA---EKAIAQLNSKYGK 197 SC++ AI++ G PL +++ ++ GW ++ WT+ + + L S+YG Sbjct: 153 NSCMDTLAIEAAGTGPLRQVIEELGGWRIS---------GKWTSLNFNRTLRLLMSQYGH 203 Query: 198 KVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIR 257 ++G + VI IDQP +P + E IY + Y+ ++ + L+ Sbjct: 204 FPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQE-QKIYAQIFREYLTYLNQLGTLLG 262 Query: 258 QEERLPIDENQLALEM-NKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEI 316 + + + L++ + +++ + + + E R L+ +T+ Q++ Sbjct: 263 GDPSKVQEHSSLSISITSRLFQFLRPL-------EQRRAQGKLFQMVTIDQLKEM----- 310 Query: 317 NGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARD---LQNLMSW 373 WL+ + +++S + + +VV+ EYL + ++ + + LQ+ M Sbjct: 311 -APAIDWLSCLQATFTPMSLSPS--QSLVVHDVEYLKNMSQLVEEMLLKQRDFLQSHMIL 367 Query: 374 RFIMDLVSSLSRTYKESRNAFRKALYGTTSETAT-----WRRCANYVNGNMENAVGRLYV 428 ++ L +L ++E+R + L T + W +C E + L+V Sbjct: 368 GLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPTLAALFV 427 Query: 429 EAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVS 488 AF ++ L IR+ I L +L WM+ ET+ A++K ++ +G + Sbjct: 428 REAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMG------A 481 Query: 489 NDNKLNNEYLELNYKE----DEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNA 544 ++ L E Y + + ++++ ++ +++ ++ + + W VNA Sbjct: 482 SEWALKPELARQEYNDIQLGSSFLQSVLSCVRSLRARIVQSFLQPHPQHRWKVSPWDVNA 541 Query: 545 FYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDD---NGRNFNKDG 601 +YS + +VFPAG+LQPPFF ++N+G G ++ HE+ H F G D Sbjct: 542 YYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIFYQLLLPGGCLACDN 601 Query: 602 DLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRA 661 + +E C+ Y F L N T EN AD GGL A +A Sbjct: 602 HAL-----------QEAHLCLKRHYAAF--PLPSRTSFNDSLTFLENAADVGGLAIALQA 648 Query: 662 YQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIG 721 Y + ++ E +LP LDL+ +Q+FF ++AQV C P+ + D HSP + R+ G Sbjct: 649 YSKRLLRHHGETVLPSLDLSPQQIFFRSYAQVMCRKPSPQDS-----HDTHSPPHLRVHG 703 Query: 722 TLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750 L ++ F+ F C + + +NP +C++W Sbjct: 704 PLSSTPAFARYFRCARGALLNPSSRCQLW 732 >gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] Length = 438 Score = 34.3 bits (77), Expect = 0.44 Identities = 31/132 (23%), Positives = 62/132 (46%), Gaps = 11/132 (8%) Query: 404 ETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLD------- 456 ET ++ + N M+ A L + GE ++E + + ++ +Q L+ Sbjct: 270 ETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSG 329 Query: 457 DLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLK 516 +LT D E ++ EE + +++ERI + DD+V K + +E E+ ++ + L Sbjct: 330 ELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVE----ENNELQSRLDYLT 385 Query: 517 FSQSKQLKKLRE 528 +Q+K + RE Sbjct: 386 ETQAKTEVETRE 397 >gi|157364974 sucrase-isomaltase [Homo sapiens] Length = 1827 Score = 34.3 bits (77), Expect = 0.44 Identities = 17/47 (36%), Positives = 31/47 (65%) Query: 21 KQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAA 67 +++++ LEISL VL +++TIIA+ +I + AT + + SD + A Sbjct: 3 RKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPA 49 >gi|221316699 maltase-glucoamylase [Homo sapiens] Length = 1857 Score = 33.9 bits (76), Expect = 0.57 Identities = 17/32 (53%), Positives = 25/32 (78%) Query: 19 KKKQRWTPLEISLSVLVLLLTIIAVTMIALYA 50 KK +++T LEI LSVL+L+L II++ +I L A Sbjct: 4 KKLKKFTTLEIVLSVLLLVLFIISIVLIVLLA 35 >gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] Length = 2355 Score = 33.9 bits (76), Expect = 0.57 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 605 DWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN-TLGENIADNGGLGQ 657 D W + S S FK QC+ + G+F D + H NG+N +GE G GQ Sbjct: 2188 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQ 2241 >gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] Length = 2477 Score = 33.9 bits (76), Expect = 0.57 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 605 DWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN-TLGENIADNGGLGQ 657 D W + S S FK QC+ + G+F D + H NG+N +GE G GQ Sbjct: 2310 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQ 2363 >gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] Length = 2330 Score = 33.9 bits (76), Expect = 0.57 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 605 DWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN-TLGENIADNGGLGQ 657 D W + S S FK QC+ + G+F D + H NG+N +GE G GQ Sbjct: 2163 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQ 2216 >gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] Length = 2296 Score = 33.9 bits (76), Expect = 0.57 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 605 DWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN-TLGENIADNGGLGQ 657 D W + S S FK QC+ + G+F D + H NG+N +GE G GQ Sbjct: 2129 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQ 2182 >gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] Length = 2421 Score = 33.9 bits (76), Expect = 0.57 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 605 DWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN-TLGENIADNGGLGQ 657 D W + S S FK QC+ + G+F D + H NG+N +GE G GQ Sbjct: 2254 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQ 2307 >gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] Length = 2176 Score = 33.9 bits (76), Expect = 0.57 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 605 DWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN-TLGENIADNGGLGQ 657 D W + S S FK QC+ + G+F D + H NG+N +GE G GQ Sbjct: 2009 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQ 2062 >gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 isoform 1 [Homo sapiens] Length = 443 Score = 33.5 bits (75), Expect = 0.74 Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 39/224 (17%) Query: 277 MELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNI 336 ++LE + N+ A ED DP K L+ Q LE+ G+ W + M +N Sbjct: 30 VDLENQYYNSKALKED--DP-----KAALSSFQK--VLELEGEKGEWGFKALKQMIKINF 80 Query: 337 SITNEEDVVVYAPEYLTKLKPILTK-YSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFR 395 +TN +++ + LT ++ +T+ YS + + +++ + + L Y+ + A + Sbjct: 81 KLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALK 140 Query: 396 KALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLI----------- 444 A W + +G+LY+E G+ + ++ L Sbjct: 141 DA-----KNDRLWFK--------TNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDD 187 Query: 445 ----AQIREVFIQTLDDLTWMDAETKKRA-EEKALAIKERIGYP 483 Q+ E++ + T K +A E++L IK I +P Sbjct: 188 LKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHP 231 >gi|139948432 adlican [Homo sapiens] Length = 2828 Score = 33.5 bits (75), Expect = 0.74 Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 1/30 (3%) Query: 627 GNFSWDLAGGQHLNGINTLGE-NIADNGGL 655 G FSW L G HL G TLG ++ DNG L Sbjct: 2667 GRFSWTLPNGMHLEGPQTLGRVSLLDNGTL 2696 >gi|4758104 cytochrome P450, family 7, subfamily B, polypeptide 1 [Homo sapiens] Length = 506 Score = 33.1 bits (74), Expect = 0.97 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Query: 439 VVEDLIAQIREVFI-QTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497 ++E ++ +++VF Q L +W AE I Y IV ++NK +E Sbjct: 153 LLESMMQNLKQVFEPQLLKTTSWDTAELYPFCSSIIFEITFTTIYGKVIVCDNNKFISEL 212 Query: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDK 532 + K D+ F ++ N+ +K +REK+ K Sbjct: 213 RDDFLKFDDKFAYLVSNIPIELLGNVKSIREKIIK 247 >gi|14043022 methionyl-tRNA synthetase [Homo sapiens] Length = 900 Score = 33.1 bits (74), Expect = 0.97 Identities = 14/49 (28%), Positives = 31/49 (63%) Query: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292 A +D + ++R+ + D+N++A E+ K+++L+K++A A KP + Sbjct: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892 >gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] Length = 971 Score = 32.7 bits (73), Expect = 1.3 Identities = 21/102 (20%), Positives = 52/102 (50%), Gaps = 1/102 (0%) Query: 440 VEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLE 499 +E+ + Q+ E +TL++L W + A+ K+++ + N +KLN E + Sbjct: 348 LEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDK 407 Query: 500 LNYKED-EYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA 540 +++ E + ++++ + ++++ L++ V K E G+A Sbjct: 408 NQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSA 449 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,470,328 Number of Sequences: 37866 Number of extensions: 1197793 Number of successful extensions: 3094 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 2986 Number of HSP's gapped (non-prelim): 60 length of query: 750 length of database: 18,247,518 effective HSP length: 110 effective length of query: 640 effective length of database: 14,082,258 effective search space: 9012645120 effective search space used: 9012645120 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.