Search of human proteins with 239582767

Search of human proteins with 239582767

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239582767 slingshot homolog 3 [Homo sapiens]
         (659 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239582767 slingshot homolog 3 [Homo sapiens]                      1318   0.0  
gi|239047414 slingshot 1 isoform 1 [Homo sapiens]                     440   e-123
gi|239047441 slingshot 1 isoform 2 [Homo sapiens]                     440   e-123
gi|239047498 slingshot 1 isoform 3 [Homo sapiens]                     427   e-119
gi|37674210 slingshot 2 [Homo sapiens]                                422   e-118
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi...   102   1e-21
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             97   4e-20
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             96   1e-19
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              90   6e-18
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    90   6e-18
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    90   8e-18
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              89   1e-17
gi|4503421 dual specificity phosphatase 9 [Homo sapiens]               88   3e-17
gi|75750526 dual specificity phosphatase 28 [Homo sapiens]             87   5e-17
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]             84   4e-16
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     83   9e-16
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]    83   9e-16
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               82   1e-15
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]               82   1e-15
gi|238231453 dual specificity phosphatase 7 [Homo sapiens]             79   1e-14
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    79   2e-14
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    79   2e-14
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    79   2e-14
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             78   2e-14
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              75   3e-13
gi|6005956 dual specificity phosphatase 12 [Homo sapiens]              74   3e-13
gi|56117820 testis and skeletal muscle-specific dual specificity...    74   4e-13
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    74   4e-13
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    74   4e-13
gi|56117818 muscle-restricted dual specificity phosphatase isofo...    74   6e-13

>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 1318 bits (3412), Expect = 0.0
 Identities = 659/659 (100%), Positives = 659/659 (100%)

Query: 1   MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEA 60
           MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEA
Sbjct: 1   MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEA 60

Query: 61  SSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAP 120
           SSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAP
Sbjct: 61  SSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAP 120

Query: 121 RPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDGDGG 180
           RPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDGDGG
Sbjct: 121 RPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDGDGG 180

Query: 181 FSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQ 240
           FSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQ
Sbjct: 181 FSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQ 240

Query: 241 SCLNEWTAMADLESLRPPSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQAL 300
           SCLNEWTAMADLESLRPPSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQAL
Sbjct: 241 SCLNEWTAMADLESLRPPSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQAL 300

Query: 301 ELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILN 360
           ELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILN
Sbjct: 301 ELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILN 360

Query: 361 MAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRS 420
           MAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRS
Sbjct: 361 MAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRS 420

Query: 421 AATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKV 480
           AATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKV
Sbjct: 421 AATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKV 480

Query: 481 GGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRS 540
           GGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRS
Sbjct: 481 GGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRS 540

Query: 541 ISLLEPSLELESTSETSDMPEVFSSHESSHEEPLQPFPQLARTKGGQQVDRGPQPALKSR 600
           ISLLEPSLELESTSETSDMPEVFSSHESSHEEPLQPFPQLARTKGGQQVDRGPQPALKSR
Sbjct: 541 ISLLEPSLELESTSETSDMPEVFSSHESSHEEPLQPFPQLARTKGGQQVDRGPQPALKSR 600

Query: 601 QSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA 659
           QSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA
Sbjct: 601 QSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA 659


>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
          Length = 1049

 Score =  440 bits (1131), Expect = e-123
 Identities = 243/528 (46%), Positives = 337/528 (63%), Gaps = 40/528 (7%)

Query: 1   MALVTVSRSPPGSGASTPVGPWDQAV----QRRSRLQRRQSFAVLRGAVLGLQDGGDNDD 56
           MALVT+ RSP  S AS+     +        R+  L   +SF +++GA L LQ G     
Sbjct: 1   MALVTLQRSPTPSAASSSASNSELEAGSEEDRKLNLSLSESFFMVKGAALFLQQG----- 55

Query: 57  AAEASSEPTEKAPSEEELHGDQTDFGQGS-QSPQKQE-EQRQHLHLMVQLLRPQDDIRLA 114
                S P                 GQ S Q P K   +  QHL +M+ LLR +D I+LA
Sbjct: 56  -----SSPQ----------------GQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLA 94

Query: 115 AQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVY 174
            +LE+    R+RY++VV +   +    +E +LLGVDF    S SCT+G+VL LWSDT+++
Sbjct: 95  VRLESAWADRVRYMVVVYSSGRQ--DTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIH 152

Query: 175 LDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQE 234
           LDGDGGFSV++ G+  IFKP+S+Q MW+ LQVLH+ACE A      PGG AL WA++Y+ 
Sbjct: 153 LDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYES 212

Query: 235 RLNSEQSCLNEWTAMADLESLRP--PSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVT 292
            ++SEQSC+NEW AM DLES RP  P+      +E E+ E+ I+A+L  ++   DLE+VT
Sbjct: 213 CISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVT 272

Query: 293 SKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQR 352
           SKEIR  LE ++   L++ ++FIDN+MLL++ Q D+ S IF HLYLGSEWNA+NLEELQ 
Sbjct: 273 SKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQG 332

Query: 353 NRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVH 412
           + V +ILN+ REIDNF+P  F YHN+R++DEE+  LL HW E + FI  A+   +  LVH
Sbjct: 333 SGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVH 392

Query: 413 CKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQ 472
           CKMGVSRSA+TV+AYAMK++   LE+A  +V++ R I RPN GF+RQL  Y+GIL AS+Q
Sbjct: 393 CKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQ 452

Query: 473 SH--VWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEES 518
            H  +W Q+    S  + P  + + P   LP  P+G  E ++  ++++
Sbjct: 453 RHNKLWRQQTD--SSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDA 498


>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
          Length = 692

 Score =  440 bits (1131), Expect = e-123
 Identities = 243/528 (46%), Positives = 337/528 (63%), Gaps = 40/528 (7%)

Query: 1   MALVTVSRSPPGSGASTPVGPWDQAV----QRRSRLQRRQSFAVLRGAVLGLQDGGDNDD 56
           MALVT+ RSP  S AS+     +        R+  L   +SF +++GA L LQ G     
Sbjct: 1   MALVTLQRSPTPSAASSSASNSELEAGSEEDRKLNLSLSESFFMVKGAALFLQQG----- 55

Query: 57  AAEASSEPTEKAPSEEELHGDQTDFGQGS-QSPQKQE-EQRQHLHLMVQLLRPQDDIRLA 114
                S P                 GQ S Q P K   +  QHL +M+ LLR +D I+LA
Sbjct: 56  -----SSPQ----------------GQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLA 94

Query: 115 AQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVY 174
            +LE+    R+RY++VV +   +    +E +LLGVDF    S SCT+G+VL LWSDT+++
Sbjct: 95  VRLESAWADRVRYMVVVYSSGRQ--DTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIH 152

Query: 175 LDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQE 234
           LDGDGGFSV++ G+  IFKP+S+Q MW+ LQVLH+ACE A      PGG AL WA++Y+ 
Sbjct: 153 LDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYES 212

Query: 235 RLNSEQSCLNEWTAMADLESLRP--PSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVT 292
            ++SEQSC+NEW AM DLES RP  P+      +E E+ E+ I+A+L  ++   DLE+VT
Sbjct: 213 CISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVT 272

Query: 293 SKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQR 352
           SKEIR  LE ++   L++ ++FIDN+MLL++ Q D+ S IF HLYLGSEWNA+NLEELQ 
Sbjct: 273 SKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQG 332

Query: 353 NRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVH 412
           + V +ILN+ REIDNF+P  F YHN+R++DEE+  LL HW E + FI  A+   +  LVH
Sbjct: 333 SGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVH 392

Query: 413 CKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQ 472
           CKMGVSRSA+TV+AYAMK++   LE+A  +V++ R I RPN GF+RQL  Y+GIL AS+Q
Sbjct: 393 CKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQ 452

Query: 473 SH--VWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEES 518
            H  +W Q+    S  + P  + + P   LP  P+G  E ++  ++++
Sbjct: 453 RHNKLWRQQTD--SSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDA 498


>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
          Length = 703

 Score =  427 bits (1098), Expect = e-119
 Identities = 230/489 (47%), Positives = 320/489 (65%), Gaps = 36/489 (7%)

Query: 36  QSFAVLRGAVLGLQDGGDNDDAAEASSEPTEKAPSEEELHGDQTDFGQGS-QSPQKQE-E 93
           +SF +++GA L LQ G          S P                 GQ S Q P K   +
Sbjct: 51  ESFFMVKGAALFLQQG----------SSPQ----------------GQRSLQHPHKHAGD 84

Query: 94  QRQHLHLMVQLLRPQDDIRLAAQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPD 153
             QHL +M+ LLR +D I+LA +LE+    R+RY++VV +   +    +E +LLGVDF  
Sbjct: 85  LPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMVVVYSSGRQ--DTEENILLGVDFSS 142

Query: 154 SSSPSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEA 213
             S SCT+G+VL LWSDT+++LDGDGGFSV++ G+  IFKP+S+Q MW+ LQVLH+ACE 
Sbjct: 143 KESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEV 202

Query: 214 ALGSGLVPGGSALTWASHYQERLNSEQSCLNEWTAMADLESLRP--PSAEPGGSSEQEQM 271
           A      PGG AL WA++Y+  ++SEQSC+NEW AM DLES RP  P+      +E E+ 
Sbjct: 203 ARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERT 262

Query: 272 EQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASR 331
           E+ I+A+L  ++   DLE+VTSKEIR  LE ++   L++ ++FIDN+MLL++ Q D+ S 
Sbjct: 263 ERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSL 322

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           IF HLYLGSEWNA+NLEELQ + V +ILN+ REIDNF+P  F YHN+R++DEE+  LL H
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 382

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           W E + FI  A+   +  LVHCKMGVSRSA+TV+AYAMK++   LE+A  +V++ R I R
Sbjct: 383 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 442

Query: 452 PNPGFLRQLQIYQGILTASRQSH--VWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGE 509
           PN GF+RQL  Y+GIL AS+Q H  +W Q+    S  + P  + + P   LP  P+G  E
Sbjct: 443 PNAGFMRQLSEYEGILDASKQRHNKLWRQQTD--SSLQQPVDDPAGPGDFLPETPDGTPE 500

Query: 510 EKVVGMEES 518
            ++  ++++
Sbjct: 501 SQLPFLDDA 509


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score =  422 bits (1085), Expect = e-118
 Identities = 217/479 (45%), Positives = 315/479 (65%), Gaps = 31/479 (6%)

Query: 1   MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRR---QSFAVLRGAVLGLQDGGDNDDA 57
           MALVTV RSP  S  S+P      + +   R Q R   +SF  ++GA L L  G      
Sbjct: 1   MALVTVQRSPTPSTTSSPCASEADSGEEECRSQPRSISESFLTVKGAALFLPRG------ 54

Query: 58  AEASSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQL 117
              +   T +       H                 + +QHL  M  LLRP+D+IRLA +L
Sbjct: 55  ---NGSSTPRISHRRNKHAG---------------DLQQHLQAMFILLRPEDNIRLAVRL 96

Query: 118 EAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDG 177
           E+    R RY++VVST   +    +E+++LG+DF  + S +CT+GLVLPLWSDT ++LDG
Sbjct: 97  ESTYQNRTRYMVVVSTNGRQ--DTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDG 154

Query: 178 DGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLN 237
           DGGFSV++  +  IFKP+S+Q MW+ LQ LH+ACE A      PG   LTW S+Y+  +N
Sbjct: 155 DGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARAHNYYPGSLFLTWVSYYESHIN 214

Query: 238 SEQSCLNEWTAMADLESLRP--PSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKE 295
           S+QS +NEW AM D++S RP  P+      +E+E+ E+ I+ +L +++   DLE++TSKE
Sbjct: 215 SDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENITSKE 274

Query: 296 IRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRV 355
           IR  LE+++   L+++++FIDN+M++++ Q D  ++IF H++LGSEWNA+NLE+LQ   V
Sbjct: 275 IRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGV 334

Query: 356 THILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKM 415
            +ILN+ REIDNF+P  F YHN+R++DEE+  LL +W +T++FI  A+  G+  LVHCKM
Sbjct: 335 RYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKM 394

Query: 416 GVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSH 474
           GVSRSA+TV+AYAMK+Y  +L++A  +V+E R + +PNP F+RQL+ YQGIL AS+Q H
Sbjct: 395 GVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRH 453


>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
           sapiens]
          Length = 217

 Score =  102 bits (254), Expect = 1e-21
 Identities = 54/133 (40%), Positives = 79/133 (59%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           I P L LGS+  A +L+ L++N+VTHILN+A  ++N +   FTY ++ + D     +L +
Sbjct: 69  IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           + E   FIE A+ +   VLVHC  GVSR+AA V+ + M   + S   A   V+  RP   
Sbjct: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188

Query: 452 PNPGFLRQLQIYQ 464
           PN GF+ QL+ YQ
Sbjct: 189 PNSGFMEQLRTYQ 201


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 68/205 (33%), Positives = 97/205 (47%), Gaps = 11/205 (5%)

Query: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREI---DNFYPERFTYHNVRLWDEESA 386
           +RI PHLYLGS+ +  N + + +N ++++LN +      D     RF    V + D    
Sbjct: 162 TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFM--RVPINDNYCE 219

Query: 387 QLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQEL 446
           +LLP   ++  FI+ A+     V+VHC  G+SRSA   +AY MK    S + A R V++ 
Sbjct: 220 KLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDR 279

Query: 447 RPIARPNPGFLRQLQIYQGI--LTASRQSHVWEQKVGGVSPEEHPAPEVSTPFPPL-PPE 503
           RP   PN  FL QL  Y+    L A+ Q    +      +PE  P+P    P P L PP 
Sbjct: 280 RPSISPNFNFLGQLLEYERSLKLLAALQG---DPGTPSGTPEPPPSPAAGAPLPRLPPPT 336

Query: 504 PEGGGEEKVVGMEESQAAPKEEPGP 528
            E          E   +A  E P P
Sbjct: 337 SESAATGNAAAREGGLSAGGEPPAP 361


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 68/205 (33%), Positives = 104/205 (50%), Gaps = 14/205 (6%)

Query: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREID--NFYPERFTYHNVRLWDEESAQ 387
           +RI P+LYLG + +  N E +Q+N + ++LN +      +F PE   +  V + D    +
Sbjct: 160 TRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-FLRVPVNDSFCEK 218

Query: 388 LLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELR 447
           +LP   ++  FIE A+A    VLVHC  G+SRSA   +AY MK+ + SL++A R V+E R
Sbjct: 219 ILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKR 278

Query: 448 PIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSPEEH-PAPEVSTPFPPLPPEPEG 506
           P   PN  FL QL  Y+  +         + + G   P+       +  P  P+P   EG
Sbjct: 279 PTISPNFNFLGQLLDYEKKI---------KNQTGASGPKSKLKLLHLEKPNEPVPAVSEG 329

Query: 507 GGE-EKVVGMEESQAAPKEEPGPRP 530
           G + E  +    + +A  E  G RP
Sbjct: 330 GQKSETPLSPPCADSATSEAAGQRP 354


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 60/158 (37%), Positives = 84/158 (53%), Gaps = 7/158 (4%)

Query: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYP--ERFTYHNVRLWDEESAQ 387
           ++I P LY+G+  +A + E+L +N+VTHIL++    D+  P  E   Y  +   D  S  
Sbjct: 6   NKILPGLYIGNFKDARDAEQLSKNKVTHILSVH---DSARPMLEGVKYLCIPAADSPSQN 62

Query: 388 LLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELR 447
           L  H+KE+ +FI   R +G   LVHC  GVSRS   V+AY M   +   E AL  V+  R
Sbjct: 63  LTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGR 122

Query: 448 PIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSP 485
             A PN GF RQLQ ++       Q   W ++  G SP
Sbjct: 123 SCANPNVGFQRQLQEFE--KHEVHQYRQWLKEEYGESP 158


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 2/152 (1%)

Query: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLL 389
           +++ P LYLG+  +A +L++L RN++THI+++  E      +  TY  + + D     + 
Sbjct: 6   TKVLPGLYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLLQDITYLRIPVADTPEVPIK 64

Query: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
            H+KE   FI   R  G + LVHC  G+SRS   V AY M          L  ++  RPI
Sbjct: 65  KHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPI 124

Query: 450 ARPNPGFLRQLQIYQGILTASRQSHVWEQKVG 481
           A PNPGF +QL+ + G  ++ +     E++ G
Sbjct: 125 ANPNPGFRQQLEEF-GWASSQKLRRQLEERFG 155


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 50/154 (32%), Positives = 82/154 (53%), Gaps = 2/154 (1%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPER--FTYHNVRLWDEESAQLL 389
           I P L+LG+E +A +L+ +QR  + +++N+   +  ++ E+  F Y  +   D     L 
Sbjct: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR 384

Query: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
            +++E   FIE A   G  +L+HC+ GVSRSA  V+AY MK    ++  A + V+  RPI
Sbjct: 385 QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444

Query: 450 ARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGV 483
             PN  F+ QL  ++  L       +   K+ GV
Sbjct: 445 ISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGV 478


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 47/139 (33%), Positives = 76/139 (54%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           I P LYLGS ++A+  E L    +T +LN++R           Y  + + D  +A +  H
Sbjct: 182 ILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSH 241

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           ++E   FI+  R +G  VLVHC+ G+SRS    +AY MK  +  L++A  ++++ R +  
Sbjct: 242 FQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVS 301

Query: 452 PNPGFLRQLQIYQGILTAS 470
           PN GF+ QL  Y+  +  S
Sbjct: 302 PNFGFMGQLLQYESEILPS 320


>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
          Length = 384

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 59/169 (34%), Positives = 86/169 (50%), Gaps = 4/169 (2%)

Query: 331 RIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPER--FTYHNVRLWDEESAQL 388
           +I P+LYLGS  ++ANLE L +  + +ILN+   + NF+ +   F Y  + + D  S  L
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265

Query: 389 LPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP 448
              + E   FI+ A +Q   VLVHC  GVSRS    +AY M++   SL  A   V+  + 
Sbjct: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325

Query: 449 IARPNPGFLRQLQIYQGILTASRQSHVWEQKVGG-VSPEEHPAPEVSTP 496
              PN  F+ QL  ++  L    + H  EQ  GG  S   +P    +TP
Sbjct: 326 NISPNFNFMGQLLDFERSLRL-EERHSQEQGSGGQASAASNPPSFFTTP 373


>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
          Length = 176

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 55/139 (39%), Positives = 75/139 (53%)

Query: 331 RIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLP 390
           R+ P L+LGS   A   E+L R  VT  +N++R+             V ++D+ +  LL 
Sbjct: 21  RVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLA 80

Query: 391 HWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIA 450
           H + T   +EAA   G   LV+CK G SRSAA   AY M+    SL +A + V+  RP+A
Sbjct: 81  HLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVA 140

Query: 451 RPNPGFLRQLQIYQGILTA 469
            PNPGF  QLQ Y+  L A
Sbjct: 141 EPNPGFWSQLQKYEEALQA 159


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 54/140 (38%), Positives = 77/140 (55%), Gaps = 7/140 (5%)

Query: 327 DRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFT-----YHNVRLW 381
           + A  ++P LYLG +  A N  EL+R  +TH+LN +       PE +      Y  V   
Sbjct: 60  NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAH 119

Query: 382 DEESAQLLPHWKETHRFIEAARAQ-GTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQAL 440
           D  +  +  H++    FI  A +Q G  +LVHC +GVSRSA  VLAY M  +  +L +A+
Sbjct: 120 DSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAI 179

Query: 441 RHVQELRPIARPNPGFLRQL 460
           + V++ R I  PN GFLRQL
Sbjct: 180 KKVKDHRGII-PNRGFLRQL 198


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 82.8 bits (203), Expect = 9e-16
 Identities = 46/139 (33%), Positives = 74/139 (53%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           I P LYLGS ++AA  + L    +T +LN++ +  N +   + Y  + + D   A +   
Sbjct: 199 ILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSW 258

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           + E   +I+A +     VLVHC+ G+SRSA   LAY M +    LE+A   V++ R I  
Sbjct: 259 FMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIIS 318

Query: 452 PNPGFLRQLQIYQGILTAS 470
           PN  F+ QL  ++  + A+
Sbjct: 319 PNFSFMGQLLQFESQVLAT 337


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score = 82.8 bits (203), Expect = 9e-16
 Identities = 46/139 (33%), Positives = 74/139 (53%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           I P LYLGS ++AA  + L    +T +LN++ +  N +   + Y  + + D   A +   
Sbjct: 108 ILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSW 167

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           + E   +I+A +     VLVHC+ G+SRSA   LAY M +    LE+A   V++ R I  
Sbjct: 168 FMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIIS 227

Query: 452 PNPGFLRQLQIYQGILTAS 470
           PN  F+ QL  ++  + A+
Sbjct: 228 PNFSFMGQLLQFESQVLAT 246


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 43/138 (31%), Positives = 73/138 (52%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           I P LYLGS ++A+  + L    +T ++N++    N +   + Y ++ + D   A +   
Sbjct: 177 ILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSW 236

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           + E   FI++ +  G  V VHC+ G+SRSA   LAY M+     L++A   V++ R I  
Sbjct: 237 FNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIIS 296

Query: 452 PNPGFLRQLQIYQGILTA 469
           PN  F+ QL  ++  + A
Sbjct: 297 PNFSFMGQLLQFESQVLA 314


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 43/129 (33%), Positives = 74/129 (57%)

Query: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
           I P+L+LGS  ++++L+ LQ   +T +LN++    N +   F Y ++ + D +  ++   
Sbjct: 176 ILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAW 235

Query: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
           ++E   FI+  +  G  VLVHC+ G+SRSA   LAY M+     L++A   V++ R +  
Sbjct: 236 FQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVIS 295

Query: 452 PNPGFLRQL 460
           PN  F+ QL
Sbjct: 296 PNFSFMGQL 304


>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
          Length = 419

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 4/162 (2%)

Query: 331 RIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPE--RFTYHNVRLWDEESAQL 388
           +I P+LYLG   ++ NL+ L +  + +ILN+   + N +     FTY  + + D  S  L
Sbjct: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 306

Query: 389 LPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP 448
              + E   FI+ AR++   VLVHC  G+SRS    +AY M++   SL  A   V+  + 
Sbjct: 307 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 366

Query: 449 IARPNPGFLRQLQIYQGILTASR--QSHVWEQKVGGVSPEEH 488
              PN  F+ QL  ++  L  S    +H   +++   +P  H
Sbjct: 367 NISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNH 408


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 326 RDRASRIFPHLYLGSEWNA--ANLEELQRNRVTHILNMAREID-NF----YPERFTYHNV 378
           R     I P L+LG   +A  + L  LQ++ +THI+ + + I+ NF    + + F Y  +
Sbjct: 26  RREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVL 85

Query: 379 RLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQ 438
            + D     ++  +  T  FI+ +   G  VLVH   G+SRSAA V+AY M+ +      
Sbjct: 86  DIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRD 145

Query: 439 ALRHVQELRPIARPNPGFLRQLQIYQGILTA 469
           A  +VQE R    PN GF+ QLQ Y+ I  A
Sbjct: 146 AFAYVQERRFCINPNAGFVHQLQEYEAIYLA 176


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 326 RDRASRIFPHLYLGSEWNA--ANLEELQRNRVTHILNMAREID-NF----YPERFTYHNV 378
           R     I P L+LG   +A  + L  LQ++ +THI+ + + I+ NF    + + F Y  +
Sbjct: 26  RREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVL 85

Query: 379 RLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQ 438
            + D     ++  +  T  FI+ +   G  VLVH   G+SRSAA V+AY M+ +      
Sbjct: 86  DIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRD 145

Query: 439 ALRHVQELRPIARPNPGFLRQLQIYQGILTA 469
           A  +VQE R    PN GF+ QLQ Y+ I  A
Sbjct: 146 AFAYVQERRFCINPNAGFVHQLQEYEAIYLA 176


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 326 RDRASRIFPHLYLGSEWNA--ANLEELQRNRVTHILNMAREID-NF----YPERFTYHNV 378
           R     I P L+LG   +A  + L  LQ++ +THI+ + + I+ NF    + + F Y  +
Sbjct: 26  RREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVL 85

Query: 379 RLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQ 438
            + D     ++  +  T  FI+ +   G  VLVH   G+SRSAA V+AY M+ +      
Sbjct: 86  DIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRD 145

Query: 439 ALRHVQELRPIARPNPGFLRQLQIYQGILTA 469
           A  +VQE R    PN GF+ QLQ Y+ I  A
Sbjct: 146 AFAYVQERRFCINPNAGFVHQLQEYEAIYLA 176


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 51/152 (33%), Positives = 73/152 (48%)

Query: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLL 389
           S+I   LY+ +   A N   L  N++T ++N++ E+ N   E   Y  V + D  +++L 
Sbjct: 21  SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80

Query: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
             +      I +   +    L+HC  GVSRSAA  LAY MK +  SL  A    +  RPI
Sbjct: 81  DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140

Query: 450 ARPNPGFLRQLQIYQGILTASRQSHVWEQKVG 481
            RPN GF  QL  Y+  L      H+    VG
Sbjct: 141 IRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVG 172


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 50/135 (37%), Positives = 68/135 (50%)

Query: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLL 389
           ++I   L+LG    A+N   LQ   +T I+N   EI NF   +F Y  V L D   A + 
Sbjct: 28  AQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIG 87

Query: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
            ++      I +   +    LVHC  GVSRSA   +AY MK +   L +A   V+  RP+
Sbjct: 88  LYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPV 147

Query: 450 ARPNPGFLRQLQIYQ 464
            RPN GF RQL  Y+
Sbjct: 148 IRPNVGFWRQLIDYE 162


>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
          Length = 340

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 4/137 (2%)

Query: 334 PHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLW----DEESAQLL 389
           P LY G     A  + L+   +T +L +  E  +F          RL+    D+    LL
Sbjct: 32  PGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLL 91

Query: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
            H      FI  ARA+G  VLVHC  GVSRS A + A+ MK  +   E+A   +Q L+P 
Sbjct: 92  SHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPE 151

Query: 450 ARPNPGFLRQLQIYQGI 466
           A+ N GF  QL++YQ +
Sbjct: 152 AKMNEGFEWQLKLYQAM 168


>gi|56117820 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 2 [Homo sapiens]
          Length = 248

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 68/217 (31%), Positives = 110/217 (50%), Gaps = 27/217 (12%)

Query: 270 QMEQAIRA---------ELWKVLDVSD-LESVTSKEIRQALELRLGLPLQQYRD--FIDN 317
           ++E+ +RA         E+W  L + D ++S+  +++R+  ++   +    Y+       
Sbjct: 23  ELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRRP-KIHGAVQASPYQPPTLASL 81

Query: 318 QMLLLVAQR---DRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAR---EIDN---F 368
           Q LL V Q    +    ++P L+LG  + A +  +L +  +TH++N A    ++D    F
Sbjct: 82  QRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKF 141

Query: 369 YPER-FTYHNVRLWDEESAQLLPHWKETHRFIEAARA--QGTHVLVHCKMGVSRSAATVL 425
           Y      Y+ +   D     L  ++    R+I AA +  QG  VLVHC MGVSRSA  VL
Sbjct: 142 YRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQG-RVLVHCAMGVSRSATLVL 200

Query: 426 AYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQI 462
           A+ M     +L +A++ VQ  R I  PN GFLRQLQ+
Sbjct: 201 AFLMICENMTLVEAIQTVQAHRNIC-PNSGFLRQLQV 236


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 42/136 (30%), Positives = 69/136 (50%), Gaps = 2/136 (1%)

Query: 350 LQRNRVTHILNMAREIDNFYPER--FTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGT 407
           +QR  + +++N+   +  ++ E+  F Y  +   D     L  +++E   FIE A   G 
Sbjct: 1   MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60

Query: 408 HVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGIL 467
            +L+HC+ GVSRSA  V+AY MK    ++  A + V+  RPI  PN  F+ QL  ++  L
Sbjct: 61  GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120

Query: 468 TASRQSHVWEQKVGGV 483
                  +   K+ GV
Sbjct: 121 NNGVTPRILTPKLMGV 136


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 42/136 (30%), Positives = 69/136 (50%), Gaps = 2/136 (1%)

Query: 350 LQRNRVTHILNMAREIDNFYPER--FTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGT 407
           +QR  + +++N+   +  ++ E+  F Y  +   D     L  +++E   FIE A   G 
Sbjct: 1   MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60

Query: 408 HVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGIL 467
            +L+HC+ GVSRSA  V+AY MK    ++  A + V+  RPI  PN  F+ QL  ++  L
Sbjct: 61  GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120

Query: 468 TASRQSHVWEQKVGGV 483
                  +   K+ GV
Sbjct: 121 NNGVTPRILTPKLMGV 136


>gi|56117818 muscle-restricted dual specificity phosphatase isoform
           1 [Homo sapiens]
          Length = 188

 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 51/140 (36%), Positives = 70/140 (50%), Gaps = 8/140 (5%)

Query: 328 RASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREI------DNFYPERFTYHNVRLW 381
           R   ++P+L++G    A N  EL +  +TH+LN A +        +FY    +Y  V   
Sbjct: 37  RVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAH 96

Query: 382 DEESAQLLPHWKETHRFIEAA-RAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQAL 440
           D     +  ++     FI  A    G  VLVHC +GVSRSA  VLAY M     SL QA+
Sbjct: 97  DLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAV 156

Query: 441 RHVQELRPIARPNPGFLRQL 460
             V++ R +  PN GFL QL
Sbjct: 157 ITVRQHRWVF-PNRGFLHQL 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,920,541
Number of Sequences: 37866
Number of extensions: 1543498
Number of successful extensions: 7707
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 7158
Number of HSP's gapped (non-prelim): 686
length of query: 659
length of database: 18,247,518
effective HSP length: 109
effective length of query: 550
effective length of database: 14,120,124
effective search space: 7766068200
effective search space used: 7766068200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.