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Search of human proteins with 238859647
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238859647 G protein-coupled receptor 128 [Homo sapiens]
(797 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238859647 G protein-coupled receptor 128 [Homo sapiens] 1582 0.0
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho... 182 1e-45
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom... 182 1e-45
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho... 182 1e-45
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom... 182 1e-45
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 159 7e-39
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 159 7e-39
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 159 7e-39
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 159 7e-39
gi|163792198 latrophilin 3 precursor [Homo sapiens] 156 6e-38
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 148 2e-35
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 145 1e-34
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 145 1e-34
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 145 1e-34
gi|6912464 latrophilin 2 precursor [Homo sapiens] 139 1e-32
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 135 1e-31
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 135 1e-31
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 131 2e-30
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 126 9e-29
gi|24475871 G protein-coupled receptor 114 [Homo sapiens] 123 8e-28
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 119 1e-26
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 117 4e-26
gi|229093087 G protein-coupled receptor 97 [Homo sapiens] 117 5e-26
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] 116 7e-26
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 114 5e-25
gi|40807489 egf-like module containing, mucin-like, hormone rece... 110 4e-24
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 108 2e-23
gi|23397681 egf-like module containing, mucin-like, hormone rece... 107 3e-23
gi|23397693 egf-like module containing, mucin-like, hormone rece... 107 3e-23
gi|23397691 egf-like module containing, mucin-like, hormone rece... 107 3e-23
>gi|238859647 G protein-coupled receptor 128 [Homo sapiens]
Length = 797
Score = 1582 bits (4097), Expect = 0.0
Identities = 797/797 (100%), Positives = 797/797 (100%)
Query: 1 MASCRAWNLRVLVAVVCGLLTGIILGLGIWRIVIRIQRGKSTSSSSTPTEFCRNGGTWEN 60
MASCRAWNLRVLVAVVCGLLTGIILGLGIWRIVIRIQRGKSTSSSSTPTEFCRNGGTWEN
Sbjct: 1 MASCRAWNLRVLVAVVCGLLTGIILGLGIWRIVIRIQRGKSTSSSSTPTEFCRNGGTWEN 60
Query: 61 GRCICTEEWKGLRCTIANFCENSTYMGFTFARIPVGRYGPSLQTCGKDTPNAGNPMAVRL 120
GRCICTEEWKGLRCTIANFCENSTYMGFTFARIPVGRYGPSLQTCGKDTPNAGNPMAVRL
Sbjct: 61 GRCICTEEWKGLRCTIANFCENSTYMGFTFARIPVGRYGPSLQTCGKDTPNAGNPMAVRL 120
Query: 121 CSLSLYGEIELQKVTIGNCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENIT 180
CSLSLYGEIELQKVTIGNCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENIT
Sbjct: 121 CSLSLYGEIELQKVTIGNCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENIT 180
Query: 181 SATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVAATANDDALTTLIEQMET 240
SATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVAATANDDALTTLIEQMET
Sbjct: 181 SATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVAATANDDALTTLIEQMET 240
Query: 241 YSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLN 300
YSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLN
Sbjct: 241 YSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLN 300
Query: 301 PDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQS 360
PDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQS
Sbjct: 301 PDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQS 360
Query: 361 ASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAV 420
ASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAV
Sbjct: 361 ASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAV 420
Query: 421 LMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLI 480
LMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLI
Sbjct: 421 LMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLI 480
Query: 481 FNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVT 540
FNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVT
Sbjct: 481 FNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVT 540
Query: 541 FTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWE 600
FTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWE
Sbjct: 541 FTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWE 600
Query: 601 LDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTS 660
LDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTS
Sbjct: 601 LDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTS 660
Query: 661 TKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILY 720
TKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILY
Sbjct: 661 TKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILY 720
Query: 721 TVRTKVFQSEASKVLMLLSSIGRRKSLPSVTRPRLRVKMYNFLRSLPTLHERFRLLETSP 780
TVRTKVFQSEASKVLMLLSSIGRRKSLPSVTRPRLRVKMYNFLRSLPTLHERFRLLETSP
Sbjct: 721 TVRTKVFQSEASKVLMLLSSIGRRKSLPSVTRPRLRVKMYNFLRSLPTLHERFRLLETSP 780
Query: 781 STEEITLSESDNAKESI 797
STEEITLSESDNAKESI
Sbjct: 781 STEEITLSESDNAKESI 797
>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
sapiens]
Length = 1221
Score = 182 bits (461), Expect = 1e-45
Identities = 169/667 (25%), Positives = 284/667 (42%), Gaps = 103/667 (15%)
Query: 94 PVGRYGPSLQTCGKDTPNAGNP--MAVRLCSLSLYGEIELQ--KVTIGNCNENLETLEKQ 149
P G Y PS+Q P P A R+C + + V I NC +
Sbjct: 531 PKGYYWPSIQPSEYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEA------ 584
Query: 150 VKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVS 209
N +++++ LT+D LT+ NIT+ V +I N N + S
Sbjct: 585 --------NEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFS 636
Query: 210 QLLDASEDAFQRVAATANDDALTTLIEQMETYSL-SLGNQSVVEPNIAIQ------SANF 262
+L +S+ ++ +AL T+ E L S + ++ N+A+ N
Sbjct: 637 NILSSSDSDLLE----SSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNA 692
Query: 263 SSENAVG-PSNVRFSVQKGASSSLVS--SSTFIHTNV-DGLNPDAQTELQVLLNMTKNYT 318
S ++G PSN Q S V +S + N+ + L+P E VL+ +
Sbjct: 693 ISNFSIGLPSNNESYFQMDFESGQVDPLASVILPPNLLENLSP----EDSVLVRRAQ--- 745
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F + LFQ K+ S + S + Q+ V + Q ++
Sbjct: 746 ----FTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQ---EV 798
Query: 379 YSYACVYWNLSAKD----WDTYGCQKDKGTDGFLR-CRCNHTTNFAVLMTFKK-----DY 428
+ C +W+L+ W+T GC + +D C CNH T+F VLM + D
Sbjct: 799 HHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDA 858
Query: 429 QYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFG 488
+ K L +S +GC +S A T++ + K+R+ + +L+NL ++L NLLF+
Sbjct: 859 RNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLL- 917
Query: 489 IENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSA 548
DG I + + D +C A+A LLH+FLL TFTW L A
Sbjct: 918 -----------DGWITSFNVDG--------------LCIAVAVLLHFFLLATFTWMGLEA 952
Query: 549 AQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEK- 607
+Y L++ R +IL +IGWG+PA+VV++ V+ S+N N + Y +EK
Sbjct: 953 IHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSV---VLASRNNNEVYGKESYGKEKG 1009
Query: 608 --ICWLAIPEPNGVIKSPLLWSFIVP--VTIILISNVVMFITISIKVLWKNNQNLTSTKK 663
CW I+ P+++ ++ N+ MFI + +++ +N + T +
Sbjct: 1010 DEFCW---------IQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLR 1060
Query: 664 VSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVR 723
++ + S +S+ + G+TW A+ + I F Y+F +FN+ QGL IFI +
Sbjct: 1061 EEVLRNLRSVVSLTFLLGMTWGFAFFAW---GPLNIPFMYLFSIFNSLQGLFIFIFHCAM 1117
Query: 724 TKVFQSE 730
+ Q +
Sbjct: 1118 KENVQKQ 1124
>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
sapiens]
Length = 1250
Score = 182 bits (461), Expect = 1e-45
Identities = 169/667 (25%), Positives = 284/667 (42%), Gaps = 103/667 (15%)
Query: 94 PVGRYGPSLQTCGKDTPNAGNP--MAVRLCSLSLYGEIELQ--KVTIGNCNENLETLEKQ 149
P G Y PS+Q P P A R+C + + V I NC +
Sbjct: 531 PKGYYWPSIQPSEYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEA------ 584
Query: 150 VKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVS 209
N +++++ LT+D LT+ NIT+ V +I N N + S
Sbjct: 585 --------NEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFS 636
Query: 210 QLLDASEDAFQRVAATANDDALTTLIEQMETYSL-SLGNQSVVEPNIAIQ------SANF 262
+L +S+ ++ +AL T+ E L S + ++ N+A+ N
Sbjct: 637 NILSSSDSDLLE----SSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNA 692
Query: 263 SSENAVG-PSNVRFSVQKGASSSLVS--SSTFIHTNV-DGLNPDAQTELQVLLNMTKNYT 318
S ++G PSN Q S V +S + N+ + L+P E VL+ +
Sbjct: 693 ISNFSIGLPSNNESYFQMDFESGQVDPLASVILPPNLLENLSP----EDSVLVRRAQ--- 745
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F + LFQ K+ S + S + Q+ V + Q ++
Sbjct: 746 ----FTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQ---EV 798
Query: 379 YSYACVYWNLSAKD----WDTYGCQKDKGTDGFLR-CRCNHTTNFAVLMTFKK-----DY 428
+ C +W+L+ W+T GC + +D C CNH T+F VLM + D
Sbjct: 799 HHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDA 858
Query: 429 QYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFG 488
+ K L +S +GC +S A T++ + K+R+ + +L+NL ++L NLLF+
Sbjct: 859 RNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLL- 917
Query: 489 IENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSA 548
DG I + + D +C A+A LLH+FLL TFTW L A
Sbjct: 918 -----------DGWITSFNVDG--------------LCIAVAVLLHFFLLATFTWMGLEA 952
Query: 549 AQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEK- 607
+Y L++ R +IL +IGWG+PA+VV++ V+ S+N N + Y +EK
Sbjct: 953 IHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSV---VLASRNNNEVYGKESYGKEKG 1009
Query: 608 --ICWLAIPEPNGVIKSPLLWSFIVP--VTIILISNVVMFITISIKVLWKNNQNLTSTKK 663
CW I+ P+++ ++ N+ MFI + +++ +N + T +
Sbjct: 1010 DEFCW---------IQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLR 1060
Query: 664 VSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVR 723
++ + S +S+ + G+TW A+ + I F Y+F +FN+ QGL IFI +
Sbjct: 1061 EEVLRNLRSVVSLTFLLGMTWGFAFFAW---GPLNIPFMYLFSIFNSLQGLFIFIFHCAM 1117
Query: 724 TKVFQSE 730
+ Q +
Sbjct: 1118 KENVQKQ 1124
>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
sapiens]
Length = 1193
Score = 182 bits (461), Expect = 1e-45
Identities = 169/667 (25%), Positives = 284/667 (42%), Gaps = 103/667 (15%)
Query: 94 PVGRYGPSLQTCGKDTPNAGNP--MAVRLCSLSLYGEIELQ--KVTIGNCNENLETLEKQ 149
P G Y PS+Q P P A R+C + + V I NC +
Sbjct: 503 PKGYYWPSIQPSEYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEA------ 556
Query: 150 VKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVS 209
N +++++ LT+D LT+ NIT+ V +I N N + S
Sbjct: 557 --------NEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFS 608
Query: 210 QLLDASEDAFQRVAATANDDALTTLIEQMETYSL-SLGNQSVVEPNIAIQ------SANF 262
+L +S+ ++ +AL T+ E L S + ++ N+A+ N
Sbjct: 609 NILSSSDSDLLE----SSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNA 664
Query: 263 SSENAVG-PSNVRFSVQKGASSSLVS--SSTFIHTNV-DGLNPDAQTELQVLLNMTKNYT 318
S ++G PSN Q S V +S + N+ + L+P E VL+ +
Sbjct: 665 ISNFSIGLPSNNESYFQMDFESGQVDPLASVILPPNLLENLSP----EDSVLVRRAQ--- 717
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F + LFQ K+ S + S + Q+ V + Q ++
Sbjct: 718 ----FTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQ---EV 770
Query: 379 YSYACVYWNLSAKD----WDTYGCQKDKGTDGFLR-CRCNHTTNFAVLMTFKK-----DY 428
+ C +W+L+ W+T GC + +D C CNH T+F VLM + D
Sbjct: 771 HHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDA 830
Query: 429 QYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFG 488
+ K L +S +GC +S A T++ + K+R+ + +L+NL ++L NLLF+
Sbjct: 831 RNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLL- 889
Query: 489 IENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSA 548
DG I + + D +C A+A LLH+FLL TFTW L A
Sbjct: 890 -----------DGWITSFNVDG--------------LCIAVAVLLHFFLLATFTWMGLEA 924
Query: 549 AQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEK- 607
+Y L++ R +IL +IGWG+PA+VV++ V+ S+N N + Y +EK
Sbjct: 925 IHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSV---VLASRNNNEVYGKESYGKEKG 981
Query: 608 --ICWLAIPEPNGVIKSPLLWSFIVP--VTIILISNVVMFITISIKVLWKNNQNLTSTKK 663
CW I+ P+++ ++ N+ MFI + +++ +N + T +
Sbjct: 982 DEFCW---------IQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLR 1032
Query: 664 VSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVR 723
++ + S +S+ + G+TW A+ + I F Y+F +FN+ QGL IFI +
Sbjct: 1033 EEVLRNLRSVVSLTFLLGMTWGFAFFAW---GPLNIPFMYLFSIFNSLQGLFIFIFHCAM 1089
Query: 724 TKVFQSE 730
+ Q +
Sbjct: 1090 KENVQKQ 1096
>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
sapiens]
Length = 1222
Score = 182 bits (461), Expect = 1e-45
Identities = 169/667 (25%), Positives = 284/667 (42%), Gaps = 103/667 (15%)
Query: 94 PVGRYGPSLQTCGKDTPNAGNP--MAVRLCSLSLYGEIELQ--KVTIGNCNENLETLEKQ 149
P G Y PS+Q P P A R+C + + V I NC +
Sbjct: 503 PKGYYWPSIQPSEYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEA------ 556
Query: 150 VKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVS 209
N +++++ LT+D LT+ NIT+ V +I N N + S
Sbjct: 557 --------NEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFS 608
Query: 210 QLLDASEDAFQRVAATANDDALTTLIEQMETYSL-SLGNQSVVEPNIAIQ------SANF 262
+L +S+ ++ +AL T+ E L S + ++ N+A+ N
Sbjct: 609 NILSSSDSDLLE----SSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNA 664
Query: 263 SSENAVG-PSNVRFSVQKGASSSLVS--SSTFIHTNV-DGLNPDAQTELQVLLNMTKNYT 318
S ++G PSN Q S V +S + N+ + L+P E VL+ +
Sbjct: 665 ISNFSIGLPSNNESYFQMDFESGQVDPLASVILPPNLLENLSP----EDSVLVRRAQ--- 717
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F + LFQ K+ S + S + Q+ V + Q ++
Sbjct: 718 ----FTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQ---EV 770
Query: 379 YSYACVYWNLSAKD----WDTYGCQKDKGTDGFLR-CRCNHTTNFAVLMTFKK-----DY 428
+ C +W+L+ W+T GC + +D C CNH T+F VLM + D
Sbjct: 771 HHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDA 830
Query: 429 QYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFG 488
+ K L +S +GC +S A T++ + K+R+ + +L+NL ++L NLLF+
Sbjct: 831 RNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLL- 889
Query: 489 IENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSA 548
DG I + + D +C A+A LLH+FLL TFTW L A
Sbjct: 890 -----------DGWITSFNVDG--------------LCIAVAVLLHFFLLATFTWMGLEA 924
Query: 549 AQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEK- 607
+Y L++ R +IL +IGWG+PA+VV++ V+ S+N N + Y +EK
Sbjct: 925 IHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSV---VLASRNNNEVYGKESYGKEKG 981
Query: 608 --ICWLAIPEPNGVIKSPLLWSFIVP--VTIILISNVVMFITISIKVLWKNNQNLTSTKK 663
CW I+ P+++ ++ N+ MFI + +++ +N + T +
Sbjct: 982 DEFCW---------IQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLR 1032
Query: 664 VSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVR 723
++ + S +S+ + G+TW A+ + I F Y+F +FN+ QGL IFI +
Sbjct: 1033 EEVLRNLRSVVSLTFLLGMTWGFAFFAW---GPLNIPFMYLFSIFNSLQGLFIFIFHCAM 1089
Query: 724 TKVFQSE 730
+ Q +
Sbjct: 1090 KENVQKQ 1096
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 159 bits (403), Expect = 7e-39
Identities = 142/586 (24%), Positives = 258/586 (44%), Gaps = 70/586 (11%)
Query: 153 VTAPLN-NISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQL 211
V+AP N N +S + T N + ++ + + + + + P I VS+L
Sbjct: 328 VSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLG-SLEPNLAGEMINQVSRL 386
Query: 212 LDASEDAF----QRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENA 267
L + D QR+ +D L ++SL + S+ I + +++F++
Sbjct: 387 LHSPPDMLAPLAQRLLKVVDDIGLQL---NFSNTTISLTSPSLALAVIRVNASSFNTTTF 443
Query: 268 VG--PSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVV 325
V P+N++ S++ A + + + T + ++ L P EL + F
Sbjct: 444 VAQDPANLQVSLETQAPENSIGTITLPSSLMNNL-PAHDMELASRVQ----------FNF 492
Query: 326 YQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVY 385
++ LFQ + S S I SS + ++ + +V + N + +L + CV+
Sbjct: 493 FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLK-HINPSQDEL-TVRCVF 550
Query: 386 WNLSAKD----WDTYGCQ-KDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPK---SLDIL 437
W+L W GC KD+ + + C C+H T+F VL+ + P +L +
Sbjct: 551 WDLGRNGGRGGWSDNGCSVKDRRLNETI-CTCSHLTSFGVLLDLSRTSVLPAQMMALTFI 609
Query: 438 SNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQ 497
+ +GC LS L++T++ I K+R+ + +L+ LC ++L+ NL+F+ + +Q
Sbjct: 610 TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 669
Query: 498 TSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIR 557
+C ++A LHYFLLV+FTW L A +Y L++
Sbjct: 670 G--------------------------LCISVAVFLHYFLLVSFTWMGLEAFHMYLALVK 703
Query: 558 TMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWEL-DYRQEKICWLAIPEP 616
R +IL ++GWGVPA+VV I + + G + + + CW+
Sbjct: 704 VFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NN 760
Query: 617 NGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSV 676
N V ++ F V I + NV MFI + +++ + ++ +S++ + S +
Sbjct: 761 NAVFYITVVGYFCV----IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGL 816
Query: 677 AVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTV 722
+ GITW A+ + + F Y+F +FNT QG IFI Y V
Sbjct: 817 TFLLGITWGFAFFAW---GPVNVTFMYLFAIFNTLQGFFIFIFYCV 859
Score = 30.0 bits (66), Expect = 8.8
Identities = 16/60 (26%), Positives = 26/60 (43%)
Query: 683 TWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIG 742
+WI Y M S+ + Y + T GL+ F +Y KVF + K ++ +G
Sbjct: 661 SWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVG 720
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 159 bits (403), Expect = 7e-39
Identities = 142/586 (24%), Positives = 258/586 (44%), Gaps = 70/586 (11%)
Query: 153 VTAPLN-NISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQL 211
V+AP N N +S + T N + ++ + + + + + P I VS+L
Sbjct: 336 VSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLG-SLEPNLAGEMINQVSRL 394
Query: 212 LDASEDAF----QRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENA 267
L + D QR+ +D L ++SL + S+ I + +++F++
Sbjct: 395 LHSPPDMLAPLAQRLLKVVDDIGLQL---NFSNTTISLTSPSLALAVIRVNASSFNTTTF 451
Query: 268 VG--PSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVV 325
V P+N++ S++ A + + + T + ++ L P EL + F
Sbjct: 452 VAQDPANLQVSLETQAPENSIGTITLPSSLMNNL-PAHDMELASRVQ----------FNF 500
Query: 326 YQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVY 385
++ LFQ + S S I SS + ++ + +V + N + +L + CV+
Sbjct: 501 FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLK-HINPSQDEL-TVRCVF 558
Query: 386 WNLSAKD----WDTYGCQ-KDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPK---SLDIL 437
W+L W GC KD+ + + C C+H T+F VL+ + P +L +
Sbjct: 559 WDLGRNGGRGGWSDNGCSVKDRRLNETI-CTCSHLTSFGVLLDLSRTSVLPAQMMALTFI 617
Query: 438 SNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQ 497
+ +GC LS L++T++ I K+R+ + +L+ LC ++L+ NL+F+ + +Q
Sbjct: 618 TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 677
Query: 498 TSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIR 557
+C ++A LHYFLLV+FTW L A +Y L++
Sbjct: 678 G--------------------------LCISVAVFLHYFLLVSFTWMGLEAFHMYLALVK 711
Query: 558 TMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWEL-DYRQEKICWLAIPEP 616
R +IL ++GWGVPA+VV I + + G + + + CW+
Sbjct: 712 VFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NN 768
Query: 617 NGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSV 676
N V ++ F V I + NV MFI + +++ + ++ +S++ + S +
Sbjct: 769 NAVFYITVVGYFCV----IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGL 824
Query: 677 AVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTV 722
+ GITW A+ + + F Y+F +FNT QG IFI Y V
Sbjct: 825 TFLLGITWGFAFFAW---GPVNVTFMYLFAIFNTLQGFFIFIFYCV 867
Score = 30.0 bits (66), Expect = 8.8
Identities = 16/60 (26%), Positives = 26/60 (43%)
Query: 683 TWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIG 742
+WI Y M S+ + Y + T GL+ F +Y KVF + K ++ +G
Sbjct: 669 SWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVG 728
>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
Length = 1017
Score = 159 bits (403), Expect = 7e-39
Identities = 142/586 (24%), Positives = 258/586 (44%), Gaps = 70/586 (11%)
Query: 153 VTAPLN-NISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQL 211
V+AP N N +S + T N + ++ + + + + + P I VS+L
Sbjct: 350 VSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLG-SLEPNLAGEMINQVSRL 408
Query: 212 LDASEDAF----QRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENA 267
L + D QR+ +D L ++SL + S+ I + +++F++
Sbjct: 409 LHSPPDMLAPLAQRLLKVVDDIGLQL---NFSNTTISLTSPSLALAVIRVNASSFNTTTF 465
Query: 268 VG--PSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVV 325
V P+N++ S++ A + + + T + ++ L P EL + F
Sbjct: 466 VAQDPANLQVSLETQAPENSIGTITLPSSLMNNL-PAHDMELASRVQ----------FNF 514
Query: 326 YQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVY 385
++ LFQ + S S I SS + ++ + +V + N + +L + CV+
Sbjct: 515 FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLK-HINPSQDEL-TVRCVF 572
Query: 386 WNLSAKD----WDTYGCQ-KDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPK---SLDIL 437
W+L W GC KD+ + + C C+H T+F VL+ + P +L +
Sbjct: 573 WDLGRNGGRGGWSDNGCSVKDRRLNETI-CTCSHLTSFGVLLDLSRTSVLPAQMMALTFI 631
Query: 438 SNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQ 497
+ +GC LS L++T++ I K+R+ + +L+ LC ++L+ NL+F+ + +Q
Sbjct: 632 TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 691
Query: 498 TSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIR 557
+C ++A LHYFLLV+FTW L A +Y L++
Sbjct: 692 G--------------------------LCISVAVFLHYFLLVSFTWMGLEAFHMYLALVK 725
Query: 558 TMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWEL-DYRQEKICWLAIPEP 616
R +IL ++GWGVPA+VV I + + G + + + CW+
Sbjct: 726 VFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NN 782
Query: 617 NGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSV 676
N V ++ F V I + NV MFI + +++ + ++ +S++ + S +
Sbjct: 783 NAVFYITVVGYFCV----IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGL 838
Query: 677 AVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTV 722
+ GITW A+ + + F Y+F +FNT QG IFI Y V
Sbjct: 839 TFLLGITWGFAFFAW---GPVNVTFMYLFAIFNTLQGFFIFIFYCV 881
Score = 30.0 bits (66), Expect = 8.8
Identities = 16/60 (26%), Positives = 26/60 (43%)
Query: 683 TWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIG 742
+WI Y M S+ + Y + T GL+ F +Y KVF + K ++ +G
Sbjct: 683 SWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVG 742
>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
Length = 1014
Score = 159 bits (403), Expect = 7e-39
Identities = 142/586 (24%), Positives = 258/586 (44%), Gaps = 70/586 (11%)
Query: 153 VTAPLN-NISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQL 211
V+AP N N +S + T N + ++ + + + + + P I VS+L
Sbjct: 347 VSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLG-SLEPNLAGEMINQVSRL 405
Query: 212 LDASEDAF----QRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENA 267
L + D QR+ +D L ++SL + S+ I + +++F++
Sbjct: 406 LHSPPDMLAPLAQRLLKVVDDIGLQL---NFSNTTISLTSPSLALAVIRVNASSFNTTTF 462
Query: 268 VG--PSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVV 325
V P+N++ S++ A + + + T + ++ L P EL + F
Sbjct: 463 VAQDPANLQVSLETQAPENSIGTITLPSSLMNNL-PAHDMELASRVQ----------FNF 511
Query: 326 YQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVY 385
++ LFQ + S S I SS + ++ + +V + N + +L + CV+
Sbjct: 512 FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLK-HINPSQDEL-TVRCVF 569
Query: 386 WNLSAKD----WDTYGCQ-KDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPK---SLDIL 437
W+L W GC KD+ + + C C+H T+F VL+ + P +L +
Sbjct: 570 WDLGRNGGRGGWSDNGCSVKDRRLNETI-CTCSHLTSFGVLLDLSRTSVLPAQMMALTFI 628
Query: 438 SNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQ 497
+ +GC LS L++T++ I K+R+ + +L+ LC ++L+ NL+F+ + +Q
Sbjct: 629 TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 688
Query: 498 TSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIR 557
+C ++A LHYFLLV+FTW L A +Y L++
Sbjct: 689 G--------------------------LCISVAVFLHYFLLVSFTWMGLEAFHMYLALVK 722
Query: 558 TMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWEL-DYRQEKICWLAIPEP 616
R +IL ++GWGVPA+VV I + + G + + + CW+
Sbjct: 723 VFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI---NN 779
Query: 617 NGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSV 676
N V ++ F V I + NV MFI + +++ + ++ +S++ + S +
Sbjct: 780 NAVFYITVVGYFCV----IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGL 835
Query: 677 AVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTV 722
+ GITW A+ + + F Y+F +FNT QG IFI Y V
Sbjct: 836 TFLLGITWGFAFFAW---GPVNVTFMYLFAIFNTLQGFFIFIFYCV 878
Score = 30.0 bits (66), Expect = 8.8
Identities = 16/60 (26%), Positives = 26/60 (43%)
Query: 683 TWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIG 742
+WI Y M S+ + Y + T GL+ F +Y KVF + K ++ +G
Sbjct: 680 SWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVG 739
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 156 bits (395), Expect = 6e-38
Identities = 162/694 (23%), Positives = 287/694 (41%), Gaps = 129/694 (18%)
Query: 94 PVGRYGPSLQTC----------GKDTPNAGNPMAVRLCSLSLYGEI------ELQKVTIG 137
P G G S C G D N +P + GE EL + T
Sbjct: 522 PAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRN 581
Query: 138 NCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNAS 197
+ N D+T + + V +L LT SA R + ++ R+
Sbjct: 582 HLNAG---------DITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCR 632
Query: 198 PEAKKVAIVTVSQLLDASE-DAFQRVAATANDDALTTLIEQMETYSLSLGNQSVVEP--- 253
+ + + TV+ LL +A++ + + A T L+ +E + L + +
Sbjct: 633 AYVQAM-VETVNNLLQPQALNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVR 691
Query: 254 ----NIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQV 309
NI ++ A S+E + +++F G S++ S+ + N G N + + +
Sbjct: 692 ENTDNIKLEVARLSTEGNL--EDLKFPENMGHGSTIQLSANTLKQN--GRNGEIRVAFVL 747
Query: 310 LLNM-----TKNYTKTCGFVVYQNDK--LFQSKTFTA--KSDFSQKIISSKTDENEQDQS 360
N+ T+N + G + + S TA +FS K+ +
Sbjct: 748 YNNLGPYLSTENASMKLGTEALSTNHSVIVNSPVITAAINKEFSNKVYLADP-------- 799
Query: 361 ASVDMVFSPKYNQKEFQLYSYACVYWNLSAKD----WDTYGCQKDKGTDGFLRCRCNHTT 416
+VF+ K+ ++ + ++ C +W+ S + W T GC+ C CNH T
Sbjct: 800 ----VVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLT 855
Query: 417 NFAVLMTFKK----DYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLV 472
NFAVLM + D + LD+++ VG LS+ L + + R ++ T +
Sbjct: 856 NFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNT-IHK 914
Query: 473 NLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAAL 532
NLCIS+ + LLF+ GI +++ + C AAL
Sbjct: 915 NLCISLFVAELLFLIGINRTDQPIA----------------------------CAVFAAL 946
Query: 533 LHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQ 592
LH+F L FTW L QLY +L+ + F L+G+G+PA++VA++ V Y
Sbjct: 947 LHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFY-LVGYGMPALIVAVSAAVDYR- 1004
Query: 593 NGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLW 652
Y +K+CWL + + +WSFI P T+I++ NV+ F+ I++ ++
Sbjct: 1005 ---------SYGTDKVCWLR-------LDTYFIWSFIGPATLIIMLNVI-FLGIALYKMF 1047
Query: 653 KNN----------QNLTSTKKVSSMKK-IVSTLSVAVVFGITWILAYLMLVNDDSIRIVF 701
+ N+ +K ++ +++ + G+TW LM +N+ + ++
Sbjct: 1048 HHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFG-LMYINEST--VIM 1104
Query: 702 SYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVL 735
+Y+F +FN+ QG+ IFI + V K + E K L
Sbjct: 1105 AYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCL 1138
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 148 bits (373), Expect = 2e-35
Identities = 145/635 (22%), Positives = 277/635 (43%), Gaps = 97/635 (15%)
Query: 117 AVRLCSLSLY-GEIELQKVTIGNCN------------ENLETLEKQVKDVTAPLNNISSE 163
A R CS+S+ G+ + +K C N+ ++ +DV + N+ +E
Sbjct: 2422 ATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIVDLANITISDENAEDVAEHILNLINE 2481
Query: 164 VQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVA 223
L + K+ I+ + Q S N + V + ++ +L+ ++ +
Sbjct: 2482 SPALGKEETKIIVSKISD----ISQCDEISMNLT----HVMLQIINVVLEKQNNSASDLH 2533
Query: 224 ATANDDALTTLIEQ----METYSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQK 279
+N+ + +IE+ ME +S + N +V +A+ + + + G + S ++
Sbjct: 2534 EISNE--ILRIIERTGHKME-FSGQIANLTVAGLALAVLRGDHTFD---GMAFSIHSYEE 2587
Query: 280 GASSSLVSSSTFIHTNVDGLN-PDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFT 338
G + + + + + P + TE L N+ +T F + LF++K T
Sbjct: 2588 GTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNL-----QTILFNFFGQTSLFKTKNVT 2642
Query: 339 AKSDFSQKIISSKTDENEQDQSASVDMVFSPKY---NQKEFQLYSYACVYWNLSAKD--- 392
+ ++S+ ++ Q+ + +V + ++ NQ Q++ C +W+ +
Sbjct: 2643 KA--LTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVH---CAFWDFENNNGLG 2697
Query: 393 -WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKK---DYQYPKSLDILSNVGCALSVTG 448
W++ GC+ + + C+C+H T+F VLM + D + L +++ GC +S
Sbjct: 2698 GWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIF 2757
Query: 449 LALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDF 508
L + V+ I K+RK +L+NLC ++L+ NL+F+
Sbjct: 2758 LGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLI--------------------- 2796
Query: 509 DNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFIL 568
N+ + + + C A LHYFLLV+FTW L A +Y L++ ++IL
Sbjct: 2797 -NSWLSSFQKVGV----CITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYIL 2851
Query: 569 FISLIGWGVPAIVVAITVGVIYSQNGN-NPQWELDYRQEKICWLAIPEPNGVIKSPLLWS 627
L+GWG+PAI+VAITV V G +P CW+ S S
Sbjct: 2852 KFCLVGWGIPAIMVAITVSVKKDLYGTLSP-------TTPFCWIK-------DDSIFYIS 2897
Query: 628 FIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVFGITWILA 687
+ +I + N+ MF T+ +++ +Q + T++ + + T+S+ + G+TW A
Sbjct: 2898 VVAYFCLIFLMNLSMFCTVLVQLNSVKSQ-IQKTRRKMILHDLKGTMSLTFLLGLTWGFA 2956
Query: 688 YLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTV 722
+ +R F Y+F +FNT QG IF+ + V
Sbjct: 2957 FFAW---GPMRNFFLYLFAIFNTLQGFFIFVFHCV 2988
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 145 bits (366), Expect = 1e-34
Identities = 139/617 (22%), Positives = 265/617 (42%), Gaps = 96/617 (15%)
Query: 157 LNNISSEVQILTSDANKLTAE-NITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDAS 215
L+ +VQ L D+ +AE I + ++V ++ + A V + +QLL
Sbjct: 226 LSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNL 285
Query: 216 EDAFQRVAATA----------NDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSE 265
ED + +A + ++ LT +I++ ++++G S + + A +
Sbjct: 286 EDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSA---RMKLNWAVAAGA 342
Query: 266 NAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVL-------LNMTKNYT 318
GP+ + ++ L ++S +H+ Q EL+ + + + +
Sbjct: 343 EDPGPAVAGILSIQNMTTLLANASLNLHSK-------KQAELEEIYESSIRGVQLRRLSA 395
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F+ + N K S A S + S E +D A D++ P+
Sbjct: 396 VNSIFLSHNNTKELNSPILFAFSH-----LESSDGEAGRDPPAK-DVMPGPRQE------ 443
Query: 379 YSYACVYWNLSAK---DWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLD 435
C +W + W T GCQ +G C+C+H ++FA+LM + L
Sbjct: 444 --LLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDW--KLT 499
Query: 436 ILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKN 495
+++ VG ALS+ L L ++ ++ R ++ + T + ++LCI + + + +F+ GIEN
Sbjct: 500 LITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIFLAGIENEGGQ 558
Query: 496 LQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
+ C +A LLHY L F W +L +LY+L+
Sbjct: 559 VGLR--------------------------CRLVAGLLHYCFLAAFCWMSLEGLELYFLV 592
Query: 556 IRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPE 615
+R + ++ LIG+GVP ++V ++ IYS+ P++ CWL
Sbjct: 593 VRVFQGQGLS-TRWLCLIGYGVPLLIVGVS-AAIYSKGYGRPRY---------CWLD--- 638
Query: 616 PNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKI-VSTL 674
+ LWSF+ PVT I++ N V+F+T K+ K ++ KK+ + + ++ +
Sbjct: 639 ----FEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI 694
Query: 675 SVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKV 734
+ + G TW+ L + +D S +V +Y+F + N QG +++L+ + K + E K
Sbjct: 695 AQLFLLGCTWVFG-LFIFDDRS--LVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKW 751
Query: 735 LMLLSSIGRRKSLPSVT 751
L++ + S T
Sbjct: 752 ACLVAGGSKYSEFTSTT 768
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 145 bits (366), Expect = 1e-34
Identities = 139/617 (22%), Positives = 265/617 (42%), Gaps = 96/617 (15%)
Query: 157 LNNISSEVQILTSDANKLTAE-NITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDAS 215
L+ +VQ L D+ +AE I + ++V ++ + A V + +QLL
Sbjct: 182 LSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNL 241
Query: 216 EDAFQRVAATA----------NDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSE 265
ED + +A + ++ LT +I++ ++++G S + + A +
Sbjct: 242 EDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSA---RMKLNWAVAAGA 298
Query: 266 NAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVL-------LNMTKNYT 318
GP+ + ++ L ++S +H+ Q EL+ + + + +
Sbjct: 299 EDPGPAVAGILSIQNMTTLLANASLNLHSK-------KQAELEEIYESSIRGVQLRRLSA 351
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F+ + N K S A S + S E +D A D++ P+
Sbjct: 352 VNSIFLSHNNTKELNSPILFAFSH-----LESSDGEAGRDPPAK-DVMPGPRQE------ 399
Query: 379 YSYACVYWNLSAK---DWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLD 435
C +W + W T GCQ +G C+C+H ++FA+LM + L
Sbjct: 400 --LLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDW--KLT 455
Query: 436 ILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKN 495
+++ VG ALS+ L L ++ ++ R ++ + T + ++LCI + + + +F+ GIEN
Sbjct: 456 LITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIFLAGIENEGGQ 514
Query: 496 LQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
+ C +A LLHY L F W +L +LY+L+
Sbjct: 515 VGLR--------------------------CRLVAGLLHYCFLAAFCWMSLEGLELYFLV 548
Query: 556 IRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPE 615
+R + ++ LIG+GVP ++V ++ IYS+ P++ CWL
Sbjct: 549 VRVFQGQGLS-TRWLCLIGYGVPLLIVGVS-AAIYSKGYGRPRY---------CWLD--- 594
Query: 616 PNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKI-VSTL 674
+ LWSF+ PVT I++ N V+F+T K+ K ++ KK+ + + ++ +
Sbjct: 595 ----FEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI 650
Query: 675 SVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKV 734
+ + G TW+ L + +D S +V +Y+F + N QG +++L+ + K + E K
Sbjct: 651 AQLFLLGCTWVFG-LFIFDDRS--LVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKW 707
Query: 735 LMLLSSIGRRKSLPSVT 751
L++ + S T
Sbjct: 708 ACLVAGGSKYSEFTSTT 724
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 145 bits (366), Expect = 1e-34
Identities = 139/617 (22%), Positives = 265/617 (42%), Gaps = 96/617 (15%)
Query: 157 LNNISSEVQILTSDANKLTAE-NITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDAS 215
L+ +VQ L D+ +AE I + ++V ++ + A V + +QLL
Sbjct: 275 LSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNL 334
Query: 216 EDAFQRVAATA----------NDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSE 265
ED + +A + ++ LT +I++ ++++G S + + A +
Sbjct: 335 EDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSA---RMKLNWAVAAGA 391
Query: 266 NAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVL-------LNMTKNYT 318
GP+ + ++ L ++S +H+ Q EL+ + + + +
Sbjct: 392 EDPGPAVAGILSIQNMTTLLANASLNLHSK-------KQAELEEIYESSIRGVQLRRLSA 444
Query: 319 KTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQL 378
F+ + N K S A S + S E +D A D++ P+
Sbjct: 445 VNSIFLSHNNTKELNSPILFAFSH-----LESSDGEAGRDPPAK-DVMPGPRQE------ 492
Query: 379 YSYACVYWNLSAK---DWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLD 435
C +W + W T GCQ +G C+C+H ++FA+LM + L
Sbjct: 493 --LLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDW--KLT 548
Query: 436 ILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKN 495
+++ VG ALS+ L L ++ ++ R ++ + T + ++LCI + + + +F+ GIEN
Sbjct: 549 LITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIFLAGIENEGGQ 607
Query: 496 LQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
+ C +A LLHY L F W +L +LY+L+
Sbjct: 608 VGLR--------------------------CRLVAGLLHYCFLAAFCWMSLEGLELYFLV 641
Query: 556 IRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPE 615
+R + ++ LIG+GVP ++V ++ IYS+ P++ CWL
Sbjct: 642 VRVFQGQGLS-TRWLCLIGYGVPLLIVGVS-AAIYSKGYGRPRY---------CWLD--- 687
Query: 616 PNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKI-VSTL 674
+ LWSF+ PVT I++ N V+F+T K+ K ++ KK+ + + ++ +
Sbjct: 688 ----FEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI 743
Query: 675 SVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKV 734
+ + G TW+ L + +D S +V +Y+F + N QG +++L+ + K + E K
Sbjct: 744 AQLFLLGCTWVFG-LFIFDDRS--LVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKW 800
Query: 735 LMLLSSIGRRKSLPSVT 751
L++ + S T
Sbjct: 801 ACLVAGGSKYSEFTSTT 817
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 139 bits (350), Expect = 1e-32
Identities = 147/667 (22%), Positives = 287/667 (43%), Gaps = 102/667 (15%)
Query: 94 PVGRYGPSLQTCGKDTPNAGNPMAVRLCSLSLYGEIEL-QKVTIGNCNENLETLEKQV-K 151
P G G + C T NP L + + + +L QK+ G EN +L ++ K
Sbjct: 493 PKGTRGTASYLCMIST-GTWNPKGPDLSNCTSHWVNQLAQKIRSG---ENAASLANELAK 548
Query: 152 DVTAPL--NNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIV-TV 208
P+ ++SS V+++ + L A+ + ++ + ++++ + AIV TV
Sbjct: 549 HTKGPVFAGDVSSSVRLMEQLVDILDAQ--------LQELKPSEKDSAGRSYNKAIVDTV 600
Query: 209 SQLLDASE-DAFQRVAATANDDALTTLIEQMETYSLSLGNQSVVEP--------NIAIQS 259
LL ++++ + ++ T L++ +E + L + +++EP NI ++
Sbjct: 601 DNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLAD-NLLEPTRVSMPTENIVLEV 659
Query: 260 ANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTK 319
A S+E + ++ SS +S++T + +GL +L ++ Y
Sbjct: 660 AVLSTEGQIQDFKFPLGIKGAGSSIQLSANTVKQNSRNGL-----AKLVFII-----YRS 709
Query: 320 TCGFVVYQNDKLFQSKTFTAKSD---FSQKIISSKTDENEQDQSASVDMVFSPKYNQKEF 376
F+ +N + F ++ + +IS ++ + ++F+ + +
Sbjct: 710 LGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPD- 768
Query: 377 QLYSYACVYWNLSAKD----WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFK----KDY 428
++ C +WN S + W T GC+ C C+H TNFA+LM + KD
Sbjct: 769 NYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG 828
Query: 429 QYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFG 488
+ L +++ VG +S+ LA+ + R ++ T + NLCI++ I +F+ G
Sbjct: 829 VHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNT-IHKNLCINLFIAEFIFLIG 887
Query: 489 IENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSA 548
I+ + + C A LLH+F L F W L
Sbjct: 888 IDKTKYAIA----------------------------CPIFAGLLHFFFLAAFAWMCLEG 919
Query: 549 AQLYYLLIRTMK-PLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEK 607
QLY +L+ + R +++ G+ PA VV ++ + Y Y EK
Sbjct: 920 VQLYLMLVEVFESEYSRKKYYYVA--GYLFPATVVGVSAAIDYK----------SYGTEK 967
Query: 608 ICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSM 667
CWL + + +WSFI PVT I++ N++ + K++ +N + ++ ++
Sbjct: 968 ACWLH-------VDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENI 1020
Query: 668 KK-IVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKV 726
K ++ ++ + G+TW L+ +N+++ IV +Y+F +FN QG+ IFI + K
Sbjct: 1021 KSWVLGAFALLCLLGLTWSFG-LLFINEET--IVMAYLFTIFNAFQGVFIFIFHCALQKK 1077
Query: 727 FQSEASK 733
+ E K
Sbjct: 1078 VRKEYGK 1084
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 135 bits (340), Expect = 1e-31
Identities = 96/361 (26%), Positives = 161/361 (44%), Gaps = 58/361 (16%)
Query: 383 CVYWNLSAKD----WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKS---LD 435
C +WN S + W T GC+ + C C+H TNFAVLM ++ YQ + L
Sbjct: 802 CSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLS 861
Query: 436 ILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKN 495
+++ VG +S+ LA+ + R ++ T + NLCI++ + LLF+ GI+ +
Sbjct: 862 VITWVGIVISLVCLAICISTFCFLRGLQ-TDRNTIHKNLCINLFLAELLFLVGIDKTQYE 920
Query: 496 LQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
+ C A LLHYF L F+W L LY LL
Sbjct: 921 IA----------------------------CPIFAGLLHYFFLAAFSWLCLEGVHLYLLL 952
Query: 556 IRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPE 615
+ + + L G+ PA+VV I + Y Y EK CWL
Sbjct: 953 VEVFES-EYSRTKYYYLGGYCFPALVVGIAAAIDYR----------SYGTEKACWLR--- 998
Query: 616 PNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKK-IVSTL 674
+ + +WSFI PV+ +++ N+V + K++ ++ + ++ ++K + +
Sbjct: 999 ----VDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAI 1054
Query: 675 SVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKV 734
++ + G+TW L+ +N +S +V +Y+F FN QG+ IF+ + K E SK
Sbjct: 1055 ALLFLLGLTWAFG-LLFINKES--VVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKC 1111
Query: 735 L 735
L
Sbjct: 1112 L 1112
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 135 bits (340), Expect = 1e-31
Identities = 96/361 (26%), Positives = 161/361 (44%), Gaps = 58/361 (16%)
Query: 383 CVYWNLSAKD----WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKS---LD 435
C +WN S + W T GC+ + C C+H TNFAVLM ++ YQ + L
Sbjct: 797 CSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLS 856
Query: 436 ILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKN 495
+++ VG +S+ LA+ + R ++ T + NLCI++ + LLF+ GI+ +
Sbjct: 857 VITWVGIVISLVCLAICISTFCFLRGLQ-TDRNTIHKNLCINLFLAELLFLVGIDKTQYE 915
Query: 496 LQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
+ C A LLHYF L F+W L LY LL
Sbjct: 916 IA----------------------------CPIFAGLLHYFFLAAFSWLCLEGVHLYLLL 947
Query: 556 IRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPE 615
+ + + L G+ PA+VV I + Y Y EK CWL
Sbjct: 948 VEVFES-EYSRTKYYYLGGYCFPALVVGIAAAIDYR----------SYGTEKACWLR--- 993
Query: 616 PNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKK-IVSTL 674
+ + +WSFI PV+ +++ N+V + K++ ++ + ++ ++K + +
Sbjct: 994 ----VDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAI 1049
Query: 675 SVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKV 734
++ + G+TW L+ +N +S +V +Y+F FN QG+ IF+ + K E SK
Sbjct: 1050 ALLFLLGLTWAFG-LLFINKES--VVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKC 1106
Query: 735 L 735
L
Sbjct: 1107 L 1107
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 131 bits (330), Expect = 2e-30
Identities = 165/719 (22%), Positives = 284/719 (39%), Gaps = 118/719 (16%)
Query: 91 ARIPVGRYGPSLQTCGKDT----PNAGNPMAVRLCSLSLYGEIELQKVTIGNCNENLETL 146
A P G +G +++ C + PN N ++ L + E LQ+ G + + L
Sbjct: 1997 APCPKGSFGTAVRHCDEHRGWLPPNLFNCTSITFSELKGFAE-RLQRNESGLDSGRSQQL 2055
Query: 147 EKQVKDVTA-PLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAI 205
+++ T S+V++ A +L A T F S + +
Sbjct: 2056 ALLLRNATQHTAGYFGSDVKVAYQLATRLLAHESTQRG------FGLSATQDVHFTENLL 2109
Query: 206 VTVSQLLD-ASEDAFQRVAATANDDALTTLIEQMETYSLSLGNQ---------SVVEPNI 255
S LLD A++ ++ + T A L++ E Y+ +L ++V PNI
Sbjct: 2110 RVGSALLDTANKRHWELIQQTEGGTAW--LLQHYEAYASALAQNMRHTYLSPFTIVTPNI 2167
Query: 256 AIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNP---------DAQTE 306
I N G R+ +G + ++ + +V P +AQ
Sbjct: 2168 VISVVRLDKGNFAGAKLPRYEALRGEQPPDLETTVILPESVFRETPPVVRPAGPGEAQEP 2227
Query: 307 LQVLLNMTKN--------------YTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKT 352
++ ++ Y G + + D +S + + ++S
Sbjct: 2228 EELARRQRRHPELSQGEAVASVIIYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISV 2287
Query: 353 DENEQDQSASVDMVFSPKYNQKEFQLYSYA-CVYWNLS-----AKDWDTYGCQKDKGTDG 406
++E+ ++D + ++ E + + CV+WN S W GC+ +
Sbjct: 2288 HDDEELLPRALDKPVTVQFRLLETEERTKPICVFWNHSILVSGTGGWSARGCEVVFRNES 2347
Query: 407 FLRCRCNHTTNFAVLMTF-KKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKT 465
+ C+CNH T+FAVLM +++ L L+ V +++ L LT F + R +R
Sbjct: 2348 HVSCQCNHMTSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSN 2407
Query: 466 SVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPM 525
+ NL ++ + L+F+ GI + D+P
Sbjct: 2408 Q-HGIRRNLTAALGLAQLVFLLGINQA-------------------DLPFA--------- 2438
Query: 526 CTAIAALLHYFLLVTFTWNALSAAQLYYLL--IRTMKPLPRHFILFISLIGWGVPAIVVA 583
CT IA LLH+ L TF+W L A LY L +R + P F ++GWGVPA +
Sbjct: 2439 CTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNTGPMRFYY---MLGWGVPAFITG 2495
Query: 584 ITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMF 643
+ VG+ +P+ Y CWL+I + L+WSF PV + +V ++
Sbjct: 2496 LAVGL-------DPE---GYGNPDFCWLSIYD-------TLIWSFAGPVAFAVSMSVFLY 2538
Query: 644 ITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSY 703
I + Q VS ++ + +V ++ TW+LA L+ VN D+ ++F Y
Sbjct: 2539 ILAARASCAAQRQGFEKKGPVSGLQ---PSFAVLLLLSATWLLA-LLSVNSDT--LLFHY 2592
Query: 704 IFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIGRRKSL-PSVTRPRLRVKMYN 761
+F N QG IF+ Y V +K E K L L S R+ S P++T YN
Sbjct: 2593 LFATCNCIQGPFIFLSYVVLSK----EVRKALKLACS--RKPSPDPALTTKSTLTSSYN 2645
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 126 bits (316), Expect = 9e-29
Identities = 107/433 (24%), Positives = 186/433 (42%), Gaps = 78/433 (18%)
Query: 317 YTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASV---DMVFSPKYNQ 373
Y K+ G ++ +D S+ +++ISS + ++ + + ++
Sbjct: 301 YYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHR 360
Query: 374 KEFQLYSYACVYWNLSAK----DWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFK---- 425
K Y C +WN S W + GC+ + CRCNH T+FA+LM+
Sbjct: 361 KVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIG 420
Query: 426 -KDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLL 484
KDY L ++ +G +S+ LA+ + +++ T T + NLC S+ + L+
Sbjct: 421 IKDYNI---LTRITQLGIIISLICLAICIFTFWFFSEIQSTRTT-IHKNLCCSLFLAELV 476
Query: 485 FVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWN 544
F+ GI + L C+ IA LLHYF L F W
Sbjct: 477 FLVGINTNTNKL----------------------------FCSIIAGLLHYFFLAAFAWM 508
Query: 545 ALSAAQLYYLLIRTMKP---LPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWEL 601
+ LY +++ + L ++F +F G+ PA+VV + + Y G
Sbjct: 509 CIEGIHLYLIVVGVIYNKGFLHKNFYIF----GYLSPAVVVGFSAALGYRYYGTT----- 559
Query: 602 DYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTST 661
K+CWL+ ++ +WSFI P +I++ N++ F I KV +++ L
Sbjct: 560 -----KVCWLS-------TENNFIWSFIGPACLIILVNLLAFGVIIYKV-FRHTAGL--K 604
Query: 662 KKVSSMKKIVS----TLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIF 717
+VS + I S L++ + G TWI L +V+ +V +Y+F + N QG+ IF
Sbjct: 605 PEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVH---ASVVTAYLFTVSNAFQGMFIF 661
Query: 718 ILYTVRTKVFQSE 730
+ V ++ Q E
Sbjct: 662 LFLCVLSRKIQEE 674
>gi|24475871 G protein-coupled receptor 114 [Homo sapiens]
Length = 528
Score = 123 bits (308), Expect = 8e-28
Identities = 97/387 (25%), Positives = 166/387 (42%), Gaps = 57/387 (14%)
Query: 371 YNQKEFQLYSYACVYWNLSAKD-----WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFK 425
++ + + Y+ CV+W A+ W GC+ ++ + + CRCNH T FAVLM
Sbjct: 177 WHNQSLEGYTLTCVFWKEGARKQPWGGWSPEGCRTEQPSHSQVLCRCNHLTYFAVLMQLS 236
Query: 426 K---DYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFN 482
+ L +S VGC++S+ +TV+ RK + S+T + +NL S+L+ N
Sbjct: 237 PALVPAELLAPLTYISLVGCSISIVASLITVLLHFHFRK-QSDSLTRIHMNLHASVLLLN 295
Query: 483 LLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFT 542
+ F+ P +P CTA+AA LHY LL T
Sbjct: 296 IAFLLS-------------------------PAFAMSPVPGSACTALAAALHYALLSCLT 330
Query: 543 WNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGN-----NP 597
W A+ LY LL R R ++ + ++GWG PA++V +++ V S G
Sbjct: 331 WMAIEGFNLYLLLGRVYNIYIRRYVFKLGVLGWGAPALLVLLSLSVKSSVYGPCTIPVFD 390
Query: 598 QWE--LDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLW--K 653
WE ++ ICW ++SP++ S +V L S + + + LW +
Sbjct: 391 SWENGTGFQNMSICW---------VRSPVVHSVLVMGYGGLTS--LFNLVVLAWALWTLR 439
Query: 654 NNQNLTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQG 713
+ V + V+ L + V+ G TW LA+ + ++F + N+ G
Sbjct: 440 RLRERADAPSVRACHDTVTVLGLTVLLGTTWALAFFSF---GVFLLPQLFLFTILNSLYG 496
Query: 714 LQIFILYTVRTKVFQSEASKVLMLLSS 740
+F+ + + ++EA + SS
Sbjct: 497 FFLFLWFCSQRCRSEAEAKAQIEAFSS 523
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 119 bits (297), Expect = 1e-26
Identities = 91/362 (25%), Positives = 164/362 (45%), Gaps = 65/362 (17%)
Query: 383 CVYWNLSAK-----DWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTF-KKDYQYPKSLDI 436
CV+WN S W GC+ + C+C+HT +FAVLM +++ L I
Sbjct: 2411 CVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVLMDISRRENGEVLPLKI 2470
Query: 437 LSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNL 496
++ +LS+ L + + + R +R +++ + +L +++ + L+FV GI +
Sbjct: 2471 VTYAAVSLSLAALLVAFVLLSLVRMLR-SNLHSIHKHLAVALFLSQLVFVIGINQTE--- 2526
Query: 497 QTSDGDINNIDFDNNDIPRTDTINIPNP-MCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
NP +CT +A LLHY + TF W + + +Y +L
Sbjct: 2527 --------------------------NPFLCTVVAILLHYIYMSTFAWTLVESLHVYRML 2560
Query: 556 --IRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAI 613
+R + P F ++GWG+PAIV + VG+ +PQ Y CWL+
Sbjct: 2561 TEVRNIDTGPMRFYY---VVGWGIPAIVTGLAVGL-------DPQ---GYGNPDFCWLS- 2606
Query: 614 PEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVST 673
++ L+WSF P+ ++I N V + +S KV + + K + S+ + +
Sbjct: 2607 ------LQDTLIWSFAGPIGAVIIINTVTSV-LSAKVSCQRKHHYYGKKGIVSLLR--TA 2657
Query: 674 LSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASK 733
+ ++ TW+L L+ VN D++ F Y+F +F+ QG + + + V + +
Sbjct: 2658 FLLLLLISATWLLG-LLAVNRDALS--FHYLFAIFSGLQGPFVLLFHCVLNQEVRKHLKG 2714
Query: 734 VL 735
VL
Sbjct: 2715 VL 2716
Score = 31.2 bits (69), Expect = 4.0
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 42 TSSSSTPTEFCRNGGTWENGRCICTEEWKGLRCTIA---NFCEN 82
TSS P C + WE+ C+C + + G+ C A N CEN
Sbjct: 1877 TSSPCPPNSRCHDA--WEDYSCVCDKGYLGINCVDACHLNPCEN 1918
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 117 bits (293), Expect = 4e-26
Identities = 91/359 (25%), Positives = 155/359 (43%), Gaps = 59/359 (16%)
Query: 383 CVYWNLSAK--DWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNV 440
CVYW + + W GC C C+H ++FAVLM + P L +++ V
Sbjct: 304 CVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPV-LTVITYV 362
Query: 441 GCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSD 500
G ++S+ L L + ++ + +R TS T + + L + + + +LLF+ GI+ +
Sbjct: 363 GLSVSLLCLLLAALTFLLCKAIRNTS-TSLHLQLSLCLFLAHLLFLVGIDRTE------- 414
Query: 501 GDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYY----LLI 556
P +C+ IA LHY L FTW L L+ L +
Sbjct: 415 ---------------------PKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTV 453
Query: 557 RTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEP 616
+ R + +G+GVPA+ VAI+ W Y CWL + +
Sbjct: 454 VNYSSINRLMKWIMFPVGYGVPAVTVAISAA----------SWPHLYGTADRCWLHLDQ- 502
Query: 617 NGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSV 676
+WSF+ PV I +N+V+FI + +L + +L S ++++ +
Sbjct: 503 ------GFMWSFLGPVCAIFSANLVLFILV-FWILKRKLSSLNSEVSTIQNTRMLAFKAT 555
Query: 677 AVVF--GITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASK 733
A +F G TW L L + V +Y+F + N+ QG IF++Y + ++ Q + K
Sbjct: 556 AQLFILGCTWCLGLLQV---GPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQK 611
>gi|229093087 G protein-coupled receptor 97 [Homo sapiens]
Length = 549
Score = 117 bits (292), Expect = 5e-26
Identities = 93/370 (25%), Positives = 163/370 (44%), Gaps = 54/370 (14%)
Query: 363 VDMVFSPKYNQKEFQLYSYACVYWNLS---AKDWDTYGCQKDKGTDGFLRCRCNHTTNFA 419
+++VFS +Q+ + CV+W+++ DW + GC + +G + C C+H T FA
Sbjct: 198 LEIVFS---HQRPPPNMTLTCVFWDVTKGTTGDWSSEGCSTEVRPEGTVCC-CDHLTFFA 253
Query: 420 VLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTR----KVRKTSVTWVLVNLC 475
+L+ D L +S GC +S+ LA T+I R + + + V L
Sbjct: 254 LLLRPTLDQSTVHILTRISQAGCGVSMIFLAFTIILYAFLRLSRERFKSEDAPKIHVALG 313
Query: 476 ISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHY 535
S+ + NL F+ + + +K + C A A+ HY
Sbjct: 314 GSLFLLNLAFLVNVGSGSKGSDAA--------------------------CWARGAVFHY 347
Query: 536 FLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGN 595
FLL FTW L A LY L +R H+ L +SL+GWG+PA++V I G S
Sbjct: 348 FLLCAFTWMGLEAFHLYLLAVRVFNTYFGHYFLKLSLVGWGLPALMV-IGTGSANSYGLY 406
Query: 596 NPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWK-- 653
+ + ++CW + +++ + V + + + + V+WK
Sbjct: 407 TIRDRENRTSLELCWFR--------EGTTMYALYITVHGYFLITFLFGMVVLALVVWKIF 458
Query: 654 NNQNLTSTK-KVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQ 712
T+ K + + KK+++ L ++ + G+TW LA + ++ YIF LFN+ Q
Sbjct: 459 TLSRATAVKERGKNRKKVLTLLGLSSLVGVTWGLAIFTPLGLSTV-----YIFALFNSLQ 513
Query: 713 GLQIFILYTV 722
G+ I +T+
Sbjct: 514 GVFICCWFTI 523
>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
Length = 910
Score = 116 bits (291), Expect = 7e-26
Identities = 97/367 (26%), Positives = 165/367 (44%), Gaps = 52/367 (14%)
Query: 359 QSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNF 418
Q+ S++ VF +++ E L CV+W+ S W+ GC T + C+C H T+F
Sbjct: 511 QNYSINEVFL-FFSKIESNLSQPHCVFWDFSHLQWNDAGCHLVNETQDIVTCQCTHLTSF 569
Query: 419 AVLMT-FKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVT-----WVLV 472
++LM+ F +P + ++ VG +S+ L L +I + + K K S T +V
Sbjct: 570 SILMSPFVPSTIFP-VVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMV 628
Query: 473 NLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAAL 532
N+ +S+LI ++ F+ G T D +N P+ +CTA
Sbjct: 629 NIALSLLIADVWFIVG--------ATVDTTVN-----------------PSGVCTAAVFF 663
Query: 533 LHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISL-IGWGVPAIVVAITVGVIYS 591
H+F L F W + L Y +I + +H ++ + +G+G P I+ IT+ V
Sbjct: 664 THFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQP 723
Query: 592 QNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVL 651
N Y+++ +CWL N S L +F+VP I+ N V+ + + K L
Sbjct: 724 SN--------TYKRKDVCWL-----NWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTK-L 769
Query: 652 WKN--NQNLTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFN 709
W+ + L+ K + ++ S L + + G+TW +V DS + + IF L N
Sbjct: 770 WRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIV--DSQNLAWHVIFALLN 827
Query: 710 TTQGLQI 716
QG I
Sbjct: 828 AFQGFFI 834
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 114 bits (284), Expect = 5e-25
Identities = 96/379 (25%), Positives = 169/379 (44%), Gaps = 68/379 (17%)
Query: 383 CVYWN---LSAKD--WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDIL 437
CV W+ L+ + W C+ RCRC+ T F VLM + L++L
Sbjct: 2480 CVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELL 2539
Query: 438 S---NVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNK 494
+ +V A+SV L LT + R + K++V + N+ ++ + LLF+ GI ++
Sbjct: 2540 AVFTHVVVAVSVAALVLTAAILLSLRSL-KSNVRGIHANVAAALGVAELLFLLGIHRTHN 2598
Query: 495 NLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYL 554
L +CTA+A LLHYF L TF W + LY +
Sbjct: 2599 QL----------------------------VCTAVAILLHYFFLSTFAWLFVQGLHLYRM 2630
Query: 555 LIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIP 614
+ + + R + F +GWGVPA+++ + VG+ +P+ Y CW+++
Sbjct: 2631 QVEP-RNVDRGAMRFYHALGWGVPAVLLGLAVGL-------DPE---GYGNPDFCWISVH 2679
Query: 615 EPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTL 674
E PL+WSF PV ++++ N MF+ ++ + Q KK S++ + S+
Sbjct: 2680 E-------PLIWSFAGPVVLVIVMNGTMFL-LAARTSCSTGQR--EAKKTSAL-TLRSSF 2728
Query: 675 SVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKV 734
+ ++ +W+ L+ VN + F Y+ QGL + +L+ V + ++
Sbjct: 2729 LLLLLVSASWLFG-LLAVNHSI--LAFHYLHAGLCGLQGLAVLLLFCV-----LNADARA 2780
Query: 735 LMLLSSIGRRKSLPSVTRP 753
+ + +G RK+ P RP
Sbjct: 2781 AWMPACLG-RKAAPEEARP 2798
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 110 bits (276), Expect = 4e-24
Identities = 93/352 (26%), Positives = 166/352 (47%), Gaps = 71/352 (20%)
Query: 383 CVYWNLSAKD--WDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNV 440
CV W+ K W ++GC + ++ + C CN N AV+M + SL I+S+V
Sbjct: 550 CVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMA-SGELTMDFSLYIISHV 608
Query: 441 GCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSD 500
G +S+ L L + ++ R +R + T++ ++LC+ +L+ LF+ GI ++ +
Sbjct: 609 GIIISLVCLVLAIATFLLCRSIRNHN-TYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--- 664
Query: 501 GDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIRTMK 560
C IA LHY L F W L A + +L++R +K
Sbjct: 665 -------------------------CAIIAGFLHYLFLACFFW-MLVEAVILFLMVRNLK 698
Query: 561 PLPRHF------ILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIP 614
+ +F +L I G+G+P +VV I+ V PQ Y CWL
Sbjct: 699 -VVNYFSSRNIKMLHICAFGYGLPMLVVVISASV-------QPQ---GYGMHNRCWLN-- 745
Query: 615 EPNGVIKSPLLWSFIVPV-TIILISNVVMFITISIKVLWKNNQNLTSTK-KVSSMK--KI 670
++ +WSF+ PV T+I+I+++++ T LW Q L+S +VS++K ++
Sbjct: 746 -----TETGFIWSFLGPVCTVIVINSLLLTWT-----LWILRQRLSSVNAEVSTLKDTRL 795
Query: 671 VSTLSVAVVF--GITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILY 720
++ + A +F G +W+L + + V +Y+F + N+ QG IF+++
Sbjct: 796 LTFKAFAQLFILGCSWVLGIFQI---GPVAGVMAYLFTIINSLQGAFIFLIH 844
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 108 bits (270), Expect = 2e-23
Identities = 91/375 (24%), Positives = 159/375 (42%), Gaps = 91/375 (24%)
Query: 383 CVYWNLS-----AKDWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDY--QYPKSLD 435
C W+ S + DWDT CQ + RC+C H + FAVL KD + S
Sbjct: 874 CASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPS 933
Query: 436 ILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKN 495
+ +GCA+S L + + K+ + +L+N C+S+L N+L + G ++
Sbjct: 934 VPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVG-----QS 988
Query: 496 LQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLL 555
S G +CT AA LH+F L +F W A Q Y +
Sbjct: 989 RVLSKG-----------------------VCTMTAAFLHFFFLSSFCWVLTEAWQSYLAV 1025
Query: 556 IRTMKP--LPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAI 613
I M+ + + F+ +GWG+PA+VVA++VG ++ Y CWL+
Sbjct: 1026 IGRMRTRLVRKRFL----CLGWGLPALVVAVSVGFTRTKG---------YGTSSYCWLS- 1071
Query: 614 PEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQN---------------- 657
++ LL++F+ P +I++ N+++ I + K++ ++ +
Sbjct: 1072 ------LEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWA 1125
Query: 658 ----------------LTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVF 701
L+S ++M + S+ V + +TW+ A L + D ++F
Sbjct: 1126 SLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMT--DRRSVLF 1183
Query: 702 SYIFCLFNTTQGLQI 716
+F +FN+ QG I
Sbjct: 1184 QALFAVFNSAQGFVI 1198
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 107 bits (268), Expect = 3e-23
Identities = 96/397 (24%), Positives = 170/397 (42%), Gaps = 63/397 (15%)
Query: 347 IISSKTDENE-QDQSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKD---WDTYGCQKDK 402
+IS+ N+ Q+ S+ V FS ++ CV+W W T GC
Sbjct: 448 VISAFLSNNDTQNLSSPVTFTFS---HRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIG 504
Query: 403 GTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKV 462
D CRC H ++FAVLM + L +++ +G ++S+ L L + ++ + +
Sbjct: 505 TRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAI 564
Query: 463 RKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIP 522
+ TS T + + L + + + +LLF+ I+ + +
Sbjct: 565 QNTS-TSLHLQLSLCLFLAHLLFLVAIDQTGHKV-------------------------- 597
Query: 523 NPMCTAIAALLHYFLLVTFTWNALSAAQLYY----LLIRTMKPLPRHFILFISLIGWGVP 578
+C+ IA LHY L T TW L A L+ L + + R + +G+GVP
Sbjct: 598 --LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVP 655
Query: 579 AIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILIS 638
A+ VAI+ + P Y CWL PE +W F+ PV I
Sbjct: 656 AVTVAISA-------ASRPHL---YGTPSRCWLQ-PEKG------FIWGFLGPVCAIFSV 698
Query: 639 NVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVF--GITWILAYLMLVNDDS 696
N+V+F+ +++ +L +L S ++++ + A +F G TW L L +
Sbjct: 699 NLVLFL-VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQV---GP 754
Query: 697 IRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASK 733
V +Y+F + N+ QG+ IF++Y + ++ + + K
Sbjct: 755 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK 791
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 107 bits (268), Expect = 3e-23
Identities = 96/397 (24%), Positives = 170/397 (42%), Gaps = 63/397 (15%)
Query: 347 IISSKTDENE-QDQSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKD---WDTYGCQKDK 402
+IS+ N+ Q+ S+ V FS ++ CV+W W T GC
Sbjct: 344 VISAFLSNNDTQNLSSPVTFTFS---HRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIG 400
Query: 403 GTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKV 462
D CRC H ++FAVLM + L +++ +G ++S+ L L + ++ + +
Sbjct: 401 TRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAI 460
Query: 463 RKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIP 522
+ TS T + + L + + + +LLF+ I+ + +
Sbjct: 461 QNTS-TSLHLQLSLCLFLAHLLFLVAIDQTGHKV-------------------------- 493
Query: 523 NPMCTAIAALLHYFLLVTFTWNALSAAQLYY----LLIRTMKPLPRHFILFISLIGWGVP 578
+C+ IA LHY L T TW L A L+ L + + R + +G+GVP
Sbjct: 494 --LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVP 551
Query: 579 AIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILIS 638
A+ VAI+ + P Y CWL PE +W F+ PV I
Sbjct: 552 AVTVAISA-------ASRPHL---YGTPSRCWLQ-PEKG------FIWGFLGPVCAIFSV 594
Query: 639 NVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVF--GITWILAYLMLVNDDS 696
N+V+F+ +++ +L +L S ++++ + A +F G TW L L +
Sbjct: 595 NLVLFL-VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQV---GP 650
Query: 697 IRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASK 733
V +Y+F + N+ QG+ IF++Y + ++ + + K
Sbjct: 651 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK 687
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 107 bits (268), Expect = 3e-23
Identities = 96/397 (24%), Positives = 170/397 (42%), Gaps = 63/397 (15%)
Query: 347 IISSKTDENE-QDQSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKD---WDTYGCQKDK 402
+IS+ N+ Q+ S+ V FS ++ CV+W W T GC
Sbjct: 388 VISAFLSNNDTQNLSSPVTFTFS---HRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIG 444
Query: 403 GTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKV 462
D CRC H ++FAVLM + L +++ +G ++S+ L L + ++ + +
Sbjct: 445 TRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAI 504
Query: 463 RKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIP 522
+ TS T + + L + + + +LLF+ I+ + +
Sbjct: 505 QNTS-TSLHLQLSLCLFLAHLLFLVAIDQTGHKV-------------------------- 537
Query: 523 NPMCTAIAALLHYFLLVTFTWNALSAAQLYY----LLIRTMKPLPRHFILFISLIGWGVP 578
+C+ IA LHY L T TW L A L+ L + + R + +G+GVP
Sbjct: 538 --LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVP 595
Query: 579 AIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILIS 638
A+ VAI+ + P Y CWL PE +W F+ PV I
Sbjct: 596 AVTVAISA-------ASRPHL---YGTPSRCWLQ-PEKG------FIWGFLGPVCAIFSV 638
Query: 639 NVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVF--GITWILAYLMLVNDDS 696
N+V+F+ +++ +L +L S ++++ + A +F G TW L L +
Sbjct: 639 NLVLFL-VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQV---GP 694
Query: 697 IRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASK 733
V +Y+F + N+ QG+ IF++Y + ++ + + K
Sbjct: 695 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,733,669
Number of Sequences: 37866
Number of extensions: 1107232
Number of successful extensions: 3616
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 3161
Number of HSP's gapped (non-prelim): 349
length of query: 797
length of database: 18,247,518
effective HSP length: 110
effective length of query: 687
effective length of database: 14,082,258
effective search space: 9674511246
effective search space used: 9674511246
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.