BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo sapiens] (676 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 1338 0.0 gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 1332 0.0 gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 1052 0.0 gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 213 6e-55 gi|13899342 solute carrier [Homo sapiens] 205 1e-52 gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 126 7e-29 gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 122 8e-28 gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 119 9e-27 gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 117 5e-26 gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 115 1e-25 gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 113 7e-25 gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 110 6e-24 gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 107 3e-23 gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 107 4e-23 gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 104 2e-22 gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 103 7e-22 gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 102 9e-22 gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 102 2e-21 gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 101 3e-21 gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens] 100 6e-21 gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 100 6e-21 gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 100 6e-21 gi|115430257 solute carrier family 25, member 26 [Homo sapiens] 99 1e-20 gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 99 2e-20 gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 99 2e-20 gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 99 2e-20 gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 98 3e-20 gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 97 6e-20 gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 97 6e-20 gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 96 8e-20 >gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo sapiens] Length = 676 Score = 1338 bits (3464), Expect = 0.0 Identities = 676/676 (100%), Positives = 676/676 (100%) Query: 1 MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60 MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL Sbjct: 1 MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60 Query: 61 LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120 LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT Sbjct: 61 LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120 Query: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA Sbjct: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180 Query: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL Sbjct: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240 Query: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT Sbjct: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300 Query: 301 LPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ 360 LPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ Sbjct: 301 LPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ 360 Query: 361 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF Sbjct: 361 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420 Query: 421 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 480 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF Sbjct: 421 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 480 Query: 481 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT Sbjct: 481 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540 Query: 541 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 600 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT Sbjct: 541 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 600 Query: 601 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP 660 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP Sbjct: 601 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP 660 Query: 661 LFKPSVSTSKAIGGGP 676 LFKPSVSTSKAIGGGP Sbjct: 661 LFKPSVSTSKAIGGGP 676 >gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo sapiens] Length = 675 Score = 1332 bits (3447), Expect = 0.0 Identities = 675/676 (99%), Positives = 675/676 (99%), Gaps = 1/676 (0%) Query: 1 MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60 MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL Sbjct: 1 MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 60 Query: 61 LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120 LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT Sbjct: 61 LSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTT 120 Query: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA Sbjct: 121 IHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA 180 Query: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL Sbjct: 181 IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTL 240 Query: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT Sbjct: 241 AGTRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGT 300 Query: 301 LPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ 360 LPFNLAEAQRQ KASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ Sbjct: 301 LPFNLAEAQRQ-KASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ 359 Query: 361 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF Sbjct: 360 RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 419 Query: 421 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 480 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF Sbjct: 420 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 479 Query: 481 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT Sbjct: 480 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 539 Query: 541 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 600 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT Sbjct: 540 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 599 Query: 601 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP 660 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP Sbjct: 600 YELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLP 659 Query: 661 LFKPSVSTSKAIGGGP 676 LFKPSVSTSKAIGGGP Sbjct: 660 LFKPSVSTSKAIGGGP 675 >gi|21361103 solute carrier family 25, member 12 [Homo sapiens] Length = 678 Score = 1052 bits (2721), Expect = 0.0 Identities = 522/667 (78%), Positives = 585/667 (87%), Gaps = 4/667 (0%) Query: 3 AAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLS 62 A KV TKR DP ELR IFL+YAS E +GE +M+P DFV RYL ++ + NPK V+LL+ Sbjct: 2 AVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLA 61 Query: 63 GVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIH 122 GV DQTKDGLIS+QEF+AFESVLCAPD++F+VAFQLFDK+G GEVTFE+VK++FGQT IH Sbjct: 62 GVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIH 121 Query: 123 QHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTAID 182 HIPFNWD EF++LHFG RK+HL Y EFTQFL E+QLEHA+QAF +D +++G ++ +D Sbjct: 122 HHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLD 181 Query: 183 FRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAG 242 F DIMVTIR H+LTPFVEE LV+AAGG+ SHQVSFSYFN FNSLLNNMEL+RKIYSTLAG Sbjct: 182 FSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAG 241 Query: 243 TRKDVEVTKEEFVLAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGTLP 302 TRKDVEVTKEEF +A ++GQVTP+E+DIL+QLADLY GR+TLADIERIAPL EG LP Sbjct: 242 TRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALP 301 Query: 303 FNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRS 362 +NLAE QRQQ S RP+ LQ+AESAYRF LGSVAGAVGATAVYPIDLVKTRMQNQR Sbjct: 302 YNLAELQRQQ--SPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRG 359 Query: 363 TGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH 422 +GS VGELMYKNSFDCFKKVLRYEGFFGLYRGL+PQL+GVAPEKAIKLTVNDFVRDKF Sbjct: 360 SGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTR 419 Query: 423 KDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFG 482 +DGSVPL AE+LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL+V+RDLG FG Sbjct: 420 RDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFG 479 Query: 483 IYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPA 542 +YKGAKACFLRDIPFSAIYFP YAH K A+E+G V +LL AGA+AG+PAASLVTPA Sbjct: 480 LYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPA 539 Query: 543 DVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602 DVIKTRLQVAARAGQTTYSGVIDCFRKILREEGP A WKG ARVFRSSPQFGVTL+TYE Sbjct: 540 DVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYE 599 Query: 603 LLQRWFYIDFGGVKPMGSEPVPKSRI-NLPAPNPDHVGGYKLAVATFAGIENKFGLYLPL 661 LLQRWFYIDFGG+KP GSEP PKSRI +LP NPDH+GGY+LA ATFAGIENKFGLYLP Sbjct: 600 LLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPK 659 Query: 662 FK-PSVS 667 FK PSV+ Sbjct: 660 FKSPSVA 666 >gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] Length = 323 Score = 213 bits (541), Expect = 6e-55 Identities = 127/299 (42%), Positives = 164/299 (54%), Gaps = 36/299 (12%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G +AG +G T V+PIDL KTR+QNQ++ G+ +Y + DC K +R EG+FG+YRG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQN-----GQRVYTSMSDCLIKTVRSEGYFGMYRGA 69 Query: 396 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI 455 L V PEKAIKL NDF R + + L E+LAG AG QVI T P+E++KI Sbjct: 70 AVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKI 129 Query: 456 RLQVAGEIT-------------------------TGPRVSALSVVRDL----GFFGIYKG 486 +LQ AG I PR +A + RDL G G+YKG Sbjct: 130 QLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKG 189 Query: 487 AKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSL-LLAGAIAGMPAASLVTPADVI 545 A LRD+PFS +YFP +A++ + SP + LAG +AG AA V P DV+ Sbjct: 190 LGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVV 249 Query: 546 KTRLQVAAR-AGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 603 KTRLQ R + TYSG++DC RKILR EGP A KGA R +P FG+ + Y L Sbjct: 250 KTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFL 308 Score = 58.2 bits (139), Expect = 3e-08 Identities = 51/197 (25%), Positives = 79/197 (40%), Gaps = 28/197 (14%) Query: 424 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRL---QVAGEITTGPRVSALSVVRDLGF 480 D + L A+++ GG AG V P+++ K RL Q + T + VR G+ Sbjct: 3 DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGY 62 Query: 481 FGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540 FG+Y+GA P AI + + + +++ +LAG AG + T Sbjct: 63 FGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTT 122 Query: 541 PADVIKTRLQVAAR----------AGQTTYSG---------------VIDCFRKILREEG 575 P +++K +LQ A R GQ + G R +LR G Sbjct: 123 PMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRG 182 Query: 576 PKALWKGAGARVFRSSP 592 L+KG GA + R P Sbjct: 183 IAGLYKGLGATLLRDVP 199 Score = 52.0 bits (123), Expect = 2e-06 Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Query: 516 DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEG 575 D Q+S + L+ G IAG+ + V P D+ KTRLQ + GQ Y+ + DC K +R EG Sbjct: 3 DKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEG 61 Query: 576 PKALWKGAGARVFRSSPQFGVTL 598 +++GA + +P+ + L Sbjct: 62 YFGMYRGAAVNLTLVTPEKAIKL 84 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/86 (38%), Positives = 45/86 (52%), Gaps = 5/86 (5%) Query: 320 RPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQN-QRSTGSFVGELMYKNSFDC 378 RP + + F G VAG+ A AV P D+VKTR+Q+ QR V E Y DC Sbjct: 216 RPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRG----VNEDTYSGILDC 271 Query: 379 FKKVLRYEGFFGLYRGLLPQLLGVAP 404 +K+LR+EG +G + L +AP Sbjct: 272 ARKILRHEGPSAFLKGAYCRALVIAP 297 >gi|13899342 solute carrier [Homo sapiens] Length = 315 Score = 205 bits (522), Expect = 1e-52 Identities = 127/294 (43%), Positives = 159/294 (54%), Gaps = 34/294 (11%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G VAG VG T V+PIDL KTR+QNQ G+ MYK DC K R EGFFG+YRG Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQH------GKAMYKGMIDCLMKTARAEGFFGMYRGA 68 Query: 396 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI 455 L V PEKAIKL NDF R M L E+LAG AG QV+ T P+E++KI Sbjct: 69 AVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKI 128 Query: 456 RLQVAGEI-----------------TTG---------PRVSALSVVRDLGFFGIYKGAKA 489 +LQ AG + TTG + A ++R G G+Y+G A Sbjct: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188 Query: 490 CFLRDIPFSAIYFPCYAHVKASFANE-DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 548 LRDIPFS IYFP +A++ NE G+ S ++G +AG AA VTP DV+KTR Sbjct: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248 Query: 549 LQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY 601 +Q + G+ YSG+ DC RK+ +EGP A KGAG R +P FG+ Y Sbjct: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302 Score = 52.0 bits (123), Expect = 2e-06 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Query: 525 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 584 L+ G +AG+ + V P D+ KTRLQ + G+ Y G+IDC K R EG +++GA Sbjct: 12 LINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69 Query: 585 ARVFRSSPQFGVTLLTYELLQR 606 + +P+ + L + +R Sbjct: 70 VNLTLVTPEKAIKLAANDFFRR 91 Score = 50.4 bits (119), Expect = 5e-06 Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 26/195 (13%) Query: 422 HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLG 479 H+D S+ A+++ GG AG V P+++ K RL Q + G + R G Sbjct: 3 HQDLSI--TAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG 60 Query: 480 FFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLV 539 FFG+Y+GA P AI + + Q + +LAG AGM + Sbjct: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT 120 Query: 540 TPADVIKTRLQVAAR-------------AGQTTYSGVIDCFRK---------ILREEGPK 577 P +++K +LQ A R ++ +G R+ +LR +G Sbjct: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180 Query: 578 ALWKGAGARVFRSSP 592 L++G GA + R P Sbjct: 181 GLYRGLGATLLRDIP 195 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 3/78 (3%) Query: 327 AESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYE 386 A A+ F G VAG++ A AV P+D++KTR+Q + +GE MY DC +K+ E Sbjct: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKG---LGEDMYSGITDCARKLWIQE 275 Query: 387 GFFGLYRGLLPQLLGVAP 404 G +G + L +AP Sbjct: 276 GPSAFMKGAGCRALVIAP 293 >gi|116235462 solute carrier family 25, member 45 isoform a [Homo sapiens] Length = 288 Score = 126 bits (316), Expect = 7e-29 Identities = 85/292 (29%), Positives = 132/292 (45%), Gaps = 26/292 (8%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392 F G ++GA+G +P D VK R+Q Q + Y+ DC K+ R+E G + Sbjct: 6 FVAGWISGALGLVLGHPFDTVKVRLQTQTT---------YRGIVDCMVKIYRHESLLGFF 56 Query: 393 RGLLPQLLGVAPEKAIKLTVND-----FVRDKFMHKDGSVPLAAEILAGGCAGGS-QVIF 446 +G+ + +A ++ V + P I GC GG Q Sbjct: 57 KGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYC 116 Query: 447 TNPLEIVKIRLQVAGEITT----------GPRVSALSVVRDLGFFGIYKGAKACFLRDIP 496 P +++K+RLQ E GP A S+ R+ G G+++GA A LRD P Sbjct: 117 LAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTP 176 Query: 497 FSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAG 556 IYF Y + + E S ++L+AG AG+ + TP D+IK+R+Q+ Sbjct: 177 TVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDG-LR 235 Query: 557 QTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 608 + Y G++DC +R+EG ++G R+ P VT L+YE L RW+ Sbjct: 236 RRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRWW 287 Score = 75.1 bits (183), Expect = 2e-13 Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 13/189 (6%) Query: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 491 E +AG +G ++ +P + VK+RLQ G + + R G +KG Sbjct: 5 EFVAGWISGALGLVLGHPFDTVKVRLQTQ-TTYRGIVDCMVKIYRHESLLGFFKGMSFPI 63 Query: 492 LRDIPFSAIYFPCYAH---VKASFANEDGQVSPGS---LLLAGAIAGMPAASLVTPADVI 545 +++ F Y++ V + ++++ + P S + LAG G A + P D+I Sbjct: 64 ASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLI 123 Query: 546 KTRLQ----VAARAGQ--TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 599 K RLQ A+ G Y G + C I REEGP+ L++GA A R +P G+ + Sbjct: 124 KVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFI 183 Query: 600 TYELLQRWF 608 TYE L R + Sbjct: 184 TYEGLCRQY 192 Score = 42.7 bits (99), Expect = 0.001 Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 5/62 (8%) Query: 521 PGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALW 580 P +AG I+G L P D +K RLQ QTTY G++DC KI R E + Sbjct: 2 PVEEFVAGWISGALGLVLGHPFDTVKVRLQT-----QTTYRGIVDCMVKIYRHESLLGFF 56 Query: 581 KG 582 KG Sbjct: 57 KG 58 >gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 [Homo sapiens] Length = 299 Score = 122 bits (307), Expect = 8e-28 Identities = 93/301 (30%), Positives = 144/301 (47%), Gaps = 19/301 (6%) Query: 318 SARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFD 377 SA+P + V E++ + G AG V ++P+D+VKTR Q QR YK+ D Sbjct: 2 SAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCA---TDPNSYKSLVD 58 Query: 378 CFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEI---L 434 F+ + + EG FG Y+G+LP +L P++A+K F +++ G V L+ + + Sbjct: 59 SFRMIFQMEGLFGFYKGILPPILAETPKRAVKF----FTFEQYKKLLGYVSLSPALTFAI 114 Query: 435 AGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL------GFFGIYKGAK 488 AG +G ++ I NP E+VK+ LQ A T + S + R + G G+ KG Sbjct: 115 AGLGSGLTEAIVVNPFEVVKVGLQ-ANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 489 ACFLRDIPFSAIYFPCYAHVKASF-ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKT 547 A R F+ +YF Y +VK N+D + G ++G A+ + P DV K+ Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKS 233 Query: 548 RLQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606 R+Q G+ Y + +EEG AL+KG ++ R P V LL YE Sbjct: 234 RIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYS 293 Query: 607 W 607 W Sbjct: 294 W 294 >gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] Length = 301 Score = 119 bits (298), Expect = 9e-27 Identities = 93/286 (32%), Positives = 140/286 (48%), Gaps = 23/286 (8%) Query: 338 VAGAVGATAV----YPIDLVKTRMQNQRSTGSFVGE-LMYKNSFDCFKKVLRYEGFFGLY 392 +AG G + +P+D VK R+Q Q S G+ MY +FDCF+K L EG GLY Sbjct: 15 LAGGFGGVCLVFVGHPLDTVKVRLQTQ--PPSLPGQPPMYSGTFDCFRKTLFREGITGLY 72 Query: 393 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFT----N 448 RG+ ++GV P A+ + V ++ A G G +FT Sbjct: 73 RGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSG---VFTTGIMT 129 Query: 449 PLEIVKIRLQV---AGEIT-TGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPC 504 P E +K LQ+ +GE TG A + ++ G GIYKG +RD+P S +YF Sbjct: 130 PGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMT 189 Query: 505 YAHVKASFANEDGQVSPGS---LLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYS 561 Y +K F E +VS S +L+AG IAG+ ++ P DV+K+R Q A + Sbjct: 190 YEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYP--N 247 Query: 562 GVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRW 607 G D R+++R+EG +L+KG A + R+ P L +E+ ++ Sbjct: 248 GFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293 Score = 83.6 bits (205), Expect = 6e-16 Identities = 56/185 (30%), Positives = 93/185 (50%), Gaps = 10/185 (5%) Query: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG--PRVSAL------SVVRDLGFFGIY 484 +LAGG G V +PL+ VK+RLQ G P S ++ R+ G G+Y Sbjct: 14 LLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFRE-GITGLY 72 Query: 485 KGAKACFLRDIP-FSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPAD 543 +G A + P F+ +F K + + +S L AG ++G+ ++TP + Sbjct: 73 RGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGE 132 Query: 544 VIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 603 IK LQ+ A +G++ Y+G +DC +K+ +E G + ++KG + R P G+ +TYE Sbjct: 133 RIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEW 192 Query: 604 LQRWF 608 L+ F Sbjct: 193 LKNIF 197 Score = 54.3 bits (129), Expect = 4e-07 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%) Query: 513 ANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQV--AARAGQ-TTYSGVIDCFRK 569 A++ +SP LLAG G+ + P D +K RLQ + GQ YSG DCFRK Sbjct: 2 ADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRK 61 Query: 570 ILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 603 L EG L++G A + +P F V + L Sbjct: 62 TLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGL 95 Score = 30.0 bits (66), Expect = 7.3 Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSF-DCFKKVLRYEGFFGLYRG 394 G +AG P D++K+R Q Y N F D ++++R EG LY+G Sbjct: 216 GGIAGIFNWAVAIPPDVLKSRFQTAPPG-------KYPNGFRDVLRELIRDEGVTSLYKG 268 Query: 395 LLPQLLGVAPEKA 407 ++ P A Sbjct: 269 FNAVMIRAFPANA 281 >gi|13775208 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 [Homo sapiens] Length = 315 Score = 117 bits (292), Expect = 5e-26 Identities = 83/292 (28%), Positives = 131/292 (44%), Gaps = 17/292 (5%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G VA AV TAV PI+ VK +Q Q S+ E YK DC ++ R +GFF +RG Sbjct: 27 GGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGN 86 Query: 396 LPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFTNPL 450 L ++ P +A+ D + FM K A + +GG AG + + PL Sbjct: 87 LANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPL 146 Query: 451 EIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYF 502 + + RL V +I GP + + + G G+Y+G I + A YF Sbjct: 147 DFARTRLGV--DIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYF 204 Query: 503 PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSG 562 Y VK S +A + + L P D ++ R+ + + + Y G Sbjct: 205 GAYDTVKGLLPKPKKTPFLVSFFIAQVVTTC-SGILSYPFDTVRRRMMMQSGEAKRQYKG 263 Query: 563 VIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGG 614 +DCF KI + EG + ++GA + V R + + L+ Y+ ++ +F+ID GG Sbjct: 264 TLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIKEFFHIDIGG 314 Score = 60.5 bits (145), Expect = 5e-09 Identities = 51/171 (29%), Positives = 79/171 (46%), Gaps = 15/171 (8%) Query: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVVRDLGFFGI 483 ++LAGG A P+E VK+ LQV + +I+ R + + R+ GFF Sbjct: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSF 82 Query: 484 YKGAKACFLRDIPFSAIYFPC---YAHVKASFANEDGQVSPGSL--LLAGAIAGMPAASL 538 ++G A +R P A+ F Y + S N++ Q L L +G AG + + Sbjct: 83 WRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCV 142 Query: 539 VTPADVIKTRLQVAARAG--QTTYSGVIDCFRKILREEGPKALWKGAGARV 587 V P D +TRL V G + + G+ DC KI + +G L++G G V Sbjct: 143 VYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSV 193 Score = 48.9 bits (115), Expect = 2e-05 Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 4/75 (5%) Query: 522 GSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPK 577 G LLAG +A + + V P + +K LQV A + Q + Y G++DC +I RE+G Sbjct: 21 GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80 Query: 578 ALWKGAGARVFRSSP 592 + W+G A V R P Sbjct: 81 SFWRGNLANVIRYFP 95 >gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] Length = 308 Score = 115 bits (289), Expect = 1e-25 Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 49/311 (15%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392 F G++ G G YP+D VK R+Q E Y + C + E +G Y Sbjct: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT---------EPKYTGIWHCVRDTYHRERVWGFY 53 Query: 393 RGLLPQLLGVAPEKAIKL-----TVNDFVRDKFMHKDGSVPLAAEILAGGCAGGS-QVIF 446 RGL + V+ ++ + R ++ + D P A+I GCA G +V Sbjct: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK-PTKADITLSGCASGLVRVFL 112 Query: 447 TNPLEIVKIRLQV-------------AGEITT----------------GPRVSALSVVRD 477 T+P E+ K+RLQ +G + GP +V R+ Sbjct: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172 Query: 478 LGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPG--SLLLAGAIAGMPA 535 G G+YKG+ A LRD A YF YA V + + G P +L+AG AG+ A Sbjct: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYA-VLCEWLSPAGHSRPDVPGVLVAGGCAGVLA 231 Query: 536 ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG 595 ++ TP DVIK+RLQ + GQ Y G++ C +REEGP+ L+KG R+ P Sbjct: 232 WAVATPMDVIKSRLQADGQ-GQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNM 290 Query: 596 VTLLTYELLQR 606 V + YE + R Sbjct: 291 VVFVAYEAVLR 301 Score = 65.5 bits (158), Expect = 2e-10 Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 43/212 (20%) Query: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-SVVRDL----GFFGIYKG 486 + +AG G V PL+ VK+R+Q T P+ + + VRD +G Y+G Sbjct: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRG 55 Query: 487 AK-----ACFLRDIPFSAIYFPCYAHV-KASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540 + + F Y C AH+ + + N D + + + L+G +G+ L + Sbjct: 56 LSLPVCTVSLVSSVSFGT-YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114 Query: 541 PADVIKTRLQVAARAG-------------------------QTTYSGVIDCFRKILREEG 575 P +V K RLQ +A + Y G + C + REEG Sbjct: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174 Query: 576 PKALWKGAGARVFRSSPQFGVTLLTYELLQRW 607 L+KG+ A V R F L+Y +L W Sbjct: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVLCEW 206 >gi|86198310 solute carrier family 25, member 29 [Homo sapiens] Length = 303 Score = 113 bits (282), Expect = 7e-25 Identities = 83/276 (30%), Positives = 123/276 (44%), Gaps = 14/276 (5%) Query: 330 AYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFF 389 A F G G G +P D VK R+Q Q V + Y+ + CFK +++ E Sbjct: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----VEKPQYRGTLHCFKSIIKQESVL 56 Query: 390 GLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNP 449 GLY+GL L+G+ A+ V H PL + LAG AG Q + P Sbjct: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDS---PLN-QFLAGAAAGAIQCVICCP 112 Query: 450 LEIVKIRLQV--AGEITT--GPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 505 +E+ K RLQ+ AG T G + G G+ +G + LR+ P +YF Y Sbjct: 113 MELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172 Query: 506 AHVKASFANEDG-QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVI 564 + + E G ++ LLLAG +G+ + P DV+K+RLQ G Y G++ Sbjct: 173 DALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGIL 232 Query: 565 DCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 600 DC + R EG + +G + + R+ P T T Sbjct: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268 Score = 82.0 bits (201), Expect = 2e-15 Identities = 59/182 (32%), Positives = 91/182 (50%), Gaps = 9/182 (4%) Query: 429 LAAEILAGGCAGG-SQVIFTNPLEIVKIRLQVAGEITTGPRVSA---LSVVRDLGFFGIY 484 +A + LAG CAGG + V+ +P + VK+RLQV R + S+++ G+Y Sbjct: 1 MALDFLAG-CAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLY 59 Query: 485 KGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADV 544 KG + + +A+ F V+ + G SP + LAGA AG + P ++ Sbjct: 60 KGLGSPLMGLTFINALVFG----VQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMEL 115 Query: 545 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604 KTRLQ+ TY G +DC +I EG + + +G + + R +P FGV LTY+ L Sbjct: 116 AKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDAL 175 Query: 605 QR 606 R Sbjct: 176 TR 177 >gi|55749577 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 [Homo sapiens] Length = 298 Score = 110 bits (274), Expect = 6e-24 Identities = 78/273 (28%), Positives = 125/273 (45%), Gaps = 20/273 (7%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392 F G VA AV TAV PI+ VK +Q Q ++ E YK DC ++ + +GF + Sbjct: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71 Query: 393 RGLLPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCAGGSQVIFT 447 RG L ++ P +A+ D + F+ HK A + +GG AG + + F Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFV 131 Query: 448 NPLEIVKIRLQVAGEITTGPRV--------SALSVVRDLGFFGIYKGAKACFLRDIPFSA 499 PL+ + RL A ++ G + + + G G+Y+G I + A Sbjct: 132 YPLDFARTRL--AADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189 Query: 500 IYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT-PADVIKTR--LQVAARAG 556 YF Y K + S ++A ++ + A LV+ P D ++ R +Q + Sbjct: 190 AYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAV--AGLVSYPFDTVRRRMMMQSGRKGA 247 Query: 557 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 589 Y+G +DC+RKI ++EG KA +KGA + V R Sbjct: 248 DIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR 280 Score = 52.0 bits (123), Expect = 2e-06 Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 17/172 (9%) Query: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQV--------AGEITTGPRVSALSVVRDLGFFGI 483 + LAGG A P+E VK+ LQV A + G + + ++ GF Sbjct: 11 DFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSF 70 Query: 484 YKGAKACFLRDIPFSAIYFPCYAHVKASFA------NEDGQVSPGSLLLAGAIAGMPAAS 537 ++G A +R P A+ F K F + + G+L GA AG + Sbjct: 71 WRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGA-AGATSLC 129 Query: 538 LVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 587 V P D +TRL V A Q + G+ DC KI + +G + L++G V Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Query: 526 LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKILREEGPKALWK 581 LAG +A + + V P + +K LQV + Q + Y G+IDC +I +E+G + W+ Sbjct: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72 Query: 582 GAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 615 G A V R F L + ++ + GGV Sbjct: 73 GNLANVIR---YFPTQALNFAFKDKYKQLFLGGV 103 >gi|157388989 solute carrier family 25, member 36 isoform a [Homo sapiens] Length = 311 Score = 107 bits (268), Expect = 3e-23 Identities = 81/298 (27%), Positives = 133/298 (44%), Gaps = 34/298 (11%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRST------------GSFVGELMYKNSFDCFKKVL 383 G G VGA P+++VKTR+Q+ T G+ V ++ C K +L Sbjct: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72 Query: 384 RYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ 443 EG L+RGL P L+GVAP +AI ++K +++ AG + Sbjct: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132 Query: 444 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSA 499 + TNP+ ++K RLQ+ R+ A VR + G G Y+G A + I + Sbjct: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191 Query: 500 IYFPCYAHVK---------ASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIK 546 I+F Y +K ++ N++ V S ++LA A + A ++ P +V++ Sbjct: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVR 251 Query: 547 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604 TRL R T Y +++EEG +L++G + R P + + TYEL+ Sbjct: 252 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 305 Score = 69.7 bits (169), Expect = 8e-12 Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%) Query: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 472 + AGGC G I T PLE+VK RLQ +AG ++ GP Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69 Query: 473 SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAG 532 ++ G +++G + P AIYF Y++ K + S +++ A+AG Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129 Query: 533 MPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGA 585 A + P +IKTRLQ+ AR G +C RK+ + +G K ++G A Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182 >gi|156071462 solute carrier family 25, member A6 [Homo sapiens] Length = 298 Score = 107 bits (267), Expect = 4e-23 Identities = 79/292 (27%), Positives = 126/292 (43%), Gaps = 14/292 (4%) Query: 325 QVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLR 384 Q A F G +A A+ TAV PI+ VK +Q Q ++ + YK DC ++ + Sbjct: 4 QAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPK 63 Query: 385 YEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFM-----HKDGSVPLAAEILAGGCA 439 +G +RG L ++ P +A+ D + F+ H A + +GG A Sbjct: 64 EQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAA 123 Query: 440 GGSQVIFTNPLEIVKIRLQV-AGEITTGPRVSAL-----SVVRDLGFFGIYKGAKACFLR 493 G + + F PL+ + RL G+ T L + + G G+Y+G Sbjct: 124 GATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQG 183 Query: 494 DIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR--LQV 551 I + A YF Y K + S ++A + + A + P D ++ R +Q Sbjct: 184 IIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAV-AGVVSYPFDTVRRRMMMQS 242 Query: 552 AARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYEL 603 + Y+G +DC+RKI R+EG KA +KGA + V R V +L EL Sbjct: 243 GRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEL 294 >gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo sapiens] Length = 314 Score = 104 bits (260), Expect = 2e-22 Identities = 85/283 (30%), Positives = 131/283 (46%), Gaps = 37/283 (13%) Query: 346 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 405 +VYP L++TR+Q Q+ G+ +Y +FD F K+LR +G GLYRG L + Sbjct: 34 SVYPFTLIRTRLQVQK------GKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISG 87 Query: 406 KAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI---------- 455 + +T + R KF+ ++AGG A T P+++V Sbjct: 88 QCY-VTTYELTR-KFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEK 145 Query: 456 --RLQVAGEITTGPRVSALSVVRDL--------GFFGIYKGAKACFLRDIPFSAIYFPCY 505 R QV G G V A +D+ G G Y+G A L IP SA+++P Y Sbjct: 146 MGRFQVRGN-PEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204 Query: 506 AHVKASFANEDGQVSPGSLLLA--GAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGV 563 + + P + A G +A A+ L P DVI+TR+QV + + + Sbjct: 205 HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSI 258 Query: 564 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606 I FR+++ EEGP L KG AR+ ++P V ++ YE L++ Sbjct: 259 ILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301 Score = 31.2 bits (69), Expect = 3.3 Identities = 16/73 (21%), Positives = 35/73 (47%), Gaps = 10/73 (13%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G +A A + P+D+++TR+Q + + F++++ EG +GL +GL Sbjct: 229 GPLAAATASILTNPMDVIRTRVQVEGKNSIIL----------TFRQLMAEEGPWGLMKGL 278 Query: 396 LPQLLGVAPEKAI 408 +++ P + Sbjct: 279 SARIISATPSTIV 291 >gi|116235466 solute carrier family 25, member 45 isoform b [Homo sapiens] Length = 246 Score = 103 bits (256), Expect = 7e-22 Identities = 70/244 (28%), Positives = 110/244 (45%), Gaps = 17/244 (6%) Query: 381 KVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVND-----FVRDKFMHKDGSVPLAAEILA 435 K+ R+E G ++G+ + +A ++ V + P I Sbjct: 3 KIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFL 62 Query: 436 GGCAGGS-QVIFTNPLEIVKIRLQVAGEITT----------GPRVSALSVVRDLGFFGIY 484 GC GG Q P +++K+RLQ E GP A S+ R+ G G++ Sbjct: 63 AGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLF 122 Query: 485 KGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADV 544 +GA A LRD P IYF Y + + E S ++L+AG AG+ + TP D+ Sbjct: 123 RGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDM 182 Query: 545 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604 IK+R+Q+ + Y G++DC +R+EG ++G R+ P VT L+YE L Sbjct: 183 IKSRMQMDG-LRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYL 241 Query: 605 QRWF 608 RW+ Sbjct: 242 LRWW 245 Score = 62.4 bits (150), Expect = 1e-09 Identities = 47/181 (25%), Positives = 79/181 (43%), Gaps = 5/181 (2%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGEL--MYKNSFDCFKKVLRYEGFFG 390 F G G + A + P DL+K R+QNQ + G Y+ C + R EG G Sbjct: 61 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 120 Query: 391 LYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPL 450 L+RG L P I + + ++ + + A ++AGG AG + + PL Sbjct: 121 LFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPL 180 Query: 451 EIVKIRLQVAG---EITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAH 507 +++K R+Q+ G + G +S +R G ++G R P +A+ F Y + Sbjct: 181 DMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEY 240 Query: 508 V 508 + Sbjct: 241 L 241 >gi|157388991 solute carrier family 25, member 36 isoform b [Homo sapiens] Length = 310 Score = 102 bits (255), Expect = 9e-22 Identities = 81/298 (27%), Positives = 132/298 (44%), Gaps = 35/298 (11%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRST------------GSFVGELMYKNSFDCFKKVL 383 G G VGA P+++VKTR+Q+ T G+ V ++ C K +L Sbjct: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72 Query: 384 RYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ 443 EG L+RGL P L+GVAP +AI ++K +++ AG + Sbjct: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132 Query: 444 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSA 499 + TNP+ ++K RLQ+ R+ A VR + G G Y+G A + I + Sbjct: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191 Query: 500 IYFPCYAHVK---------ASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIK 546 I+F Y +K ++ N++ V S ++LA A + A ++ P V++ Sbjct: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVR 250 Query: 547 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604 TRL R T Y +++EEG +L++G + R P + + TYEL+ Sbjct: 251 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304 Score = 69.7 bits (169), Expect = 8e-12 Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%) Query: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 472 + AGGC G I T PLE+VK RLQ +AG ++ GP Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69 Query: 473 SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAG 532 ++ G +++G + P AIYF Y++ K + S +++ A+AG Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129 Query: 533 MPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGA 585 A + P +IKTRLQ+ AR G +C RK+ + +G K ++G A Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182 >gi|82775373 solute carrier family 25, member 37 [Homo sapiens] Length = 338 Score = 102 bits (253), Expect = 2e-21 Identities = 83/284 (29%), Positives = 126/284 (44%), Gaps = 25/284 (8%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G++AG + + +YP+D VKTRMQ+ S + Y + + KK++R EGF+ RG+ Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQSL----SPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107 Query: 396 LPQLLGVAPEKA--------IKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFT 447 ++G P A +K T+ND H G+ LA I AG A Sbjct: 108 NVMIMGAGPAHAMYFACYENMKRTLND-----VFHHQGNSHLANGI-AGSMATLLHDAVM 161 Query: 448 NPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAH 507 NP E+VK RLQ+ +V R G Y+ +IPF +I+F Y Sbjct: 162 NPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEF 221 Query: 508 VKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQT------TYS 561 ++ N +P S +++G +AG AA+ TP DV KT L + S Sbjct: 222 LQEQ-VNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280 Query: 562 GVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 605 G+ + FR + + G +KG ARV P ++ YE + Sbjct: 281 GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/95 (26%), Positives = 46/95 (48%) Query: 512 FANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKIL 571 + N S + + AGA+AG+ S++ P D +KTR+Q + + Y+ + +KI+ Sbjct: 36 YENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIM 95 Query: 572 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606 R EG +G + + P + YE ++R Sbjct: 96 RTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKR 130 >gi|156071459 solute carrier family 25, member 5 [Homo sapiens] Length = 298 Score = 101 bits (251), Expect = 3e-21 Identities = 74/273 (27%), Positives = 118/273 (43%), Gaps = 20/273 (7%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392 F G VA A+ TAV PI+ VK +Q Q ++ + YK DC ++ + +G + Sbjct: 12 FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71 Query: 393 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVP--------LAAEILAGGCAGGSQV 444 RG L ++ P +A+ D + F+ G V A + +GG AG + + Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFL---GGVDKRTQFWLYFAGNLASGGAAGATSL 128 Query: 445 IFTNPLEIVKIRLQV------AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFS 498 F PL+ + RL A G + + + G G+Y+G I + Sbjct: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188 Query: 499 AIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR--LQVAARAG 556 A YF Y K + S ++A + + A P D ++ R +Q + Sbjct: 189 AAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAV-AGLTSYPFDTVRRRMMMQSGRKGT 247 Query: 557 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 589 Y+G +DC+RKI R+EG KA +KGA + V R Sbjct: 248 DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280 Score = 54.7 bits (130), Expect = 3e-07 Identities = 48/179 (26%), Positives = 75/179 (41%), Gaps = 15/179 (8%) Query: 424 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVV 475 D +V A + LAGG A P+E VK+ LQV + +IT + + + Sbjct: 3 DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62 Query: 476 RDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSL-----LLAGAI 530 ++ G ++G A +R P A+ F K F + + L L +G Sbjct: 63 KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGA 122 Query: 531 AGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 587 AG + V P D +TRL V + + G+ DC KI + +G K L++G V Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSV 181 Score = 50.1 bits (118), Expect = 7e-06 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 7/104 (6%) Query: 516 DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKIL 571 D VS LAG +A + + V P + +K LQV + Q T Y G+IDC +I Sbjct: 3 DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62 Query: 572 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 615 +E+G + W+G A V R F L + ++ I GGV Sbjct: 63 KEQGVLSFWRGNLANVIR---YFPTQALNFAFKDKYKQIFLGGV 103 >gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens] Length = 301 Score = 100 bits (248), Expect = 6e-21 Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 30/293 (10%) Query: 330 AYRFGLGSVAGAVGATAVY----PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRY 385 A + + AGA G TA P D +K +MQ +Y+ DC K Sbjct: 6 AIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPD--------LYRGLTDCCLKTYSQ 57 Query: 386 EGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF-----MHKDGSVPLAAEILAGGCAG 440 GF G Y+G P L+ E ++ F + + K + AG A Sbjct: 58 VGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFAS 117 Query: 441 GSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL---------SVVRDLGFFGIYKGAKACF 491 + P E+VK RLQ E+ T +++ S++R G G Y G + Sbjct: 118 AFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTL 177 Query: 492 LRDIPFSAIYFPCYAHVKASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRL 549 LR++P +F Y ++ FA+ ++ P L+L+G + G+ V P D IK+R+ Sbjct: 178 LREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRI 237 Query: 550 QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602 QV + +G+ +G I F +++ EG AL+ G + R+ P G L YE Sbjct: 238 QVLSMSGK--QAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288 Score = 71.2 bits (173), Expect = 3e-12 Identities = 48/202 (23%), Positives = 92/202 (45%), Gaps = 18/202 (8%) Query: 421 MHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGF 480 M + ++ A ++ AG G + V+ P + +K+++Q ++ G L +GF Sbjct: 1 MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGF 60 Query: 481 FGIYKGAKACFLRDIPFSAIYFPCYAHV-----KASFANEDGQVSPGSLLLAGAIAGMPA 535 G YKG + +I +++ F CY K + ++ ++S AG+ A A Sbjct: 61 RGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFA 120 Query: 536 ASLVTPADVIKTRLQV---------AARAGQTTYSGVIDCFRKILREEGPKALWKGAGAR 586 A ++ P +++K RLQ A++ T +S + + ILR++GP + G + Sbjct: 121 ALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVI----KSILRKDGPLGFYHGLSST 176 Query: 587 VFRSSPQFGVTLLTYELLQRWF 608 + R P + YEL + +F Sbjct: 177 LLREVPGYFFFFGGYELSRSFF 198 Score = 40.4 bits (93), Expect = 0.005 Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 17/120 (14%) Query: 307 EAQRQQKASG---DSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRST 363 E R ASG D PV L ++ G V G AVYP+D +K+R+Q + Sbjct: 192 ELSRSFFASGRSKDELGPVPLMLS--------GGVGGICLWLAVYPVDCIKSRIQVLSMS 243 Query: 364 GSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHK 423 G G + F V++ EG LY GL P ++ P ++ R M++ Sbjct: 244 GKQAGFIR------TFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQ 297 >gi|13994341 solute carrier family 25 member 2 [Homo sapiens] Length = 301 Score = 100 bits (248), Expect = 6e-21 Identities = 81/285 (28%), Positives = 128/285 (44%), Gaps = 32/285 (11%) Query: 339 AGAVGATAVY----PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRG 394 AGA G TA P D +K +MQ +YK DCF K G G Y+G Sbjct: 15 AGAAGGTACVLTGQPFDTIKVKMQTFPD--------LYKGLTDCFLKTYAQVGLRGFYKG 66 Query: 395 LLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEI------LAGGCAGGSQVIFTN 448 P L+ E ++ F + +F+ K + A++ AG A + Sbjct: 67 TGPALMAYVAENSVLFMCYGFCQ-QFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALC 125 Query: 449 PLEIVKIRLQVAGEITTGPRVSAL-----SVVRDL----GFFGIYKGAKACFLRDIPFSA 499 P E+VK RLQ E+ +++ SVV+ + G G Y G + L+++P Sbjct: 126 PTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYF 185 Query: 500 IYFPCYAHVKASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQ 557 +F Y ++ FA+ ++ P L+L+G +AG+ +V P D IK+R+QV + G+ Sbjct: 186 FFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGK 245 Query: 558 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602 +G I ++R EG AL+ G A + R+ P G + YE Sbjct: 246 --QAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYE 288 Score = 62.8 bits (151), Expect = 1e-09 Identities = 49/201 (24%), Positives = 88/201 (43%), Gaps = 19/201 (9%) Query: 423 KDGSVPLAAEILAGGCAGGSQVIFTN-PLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF 481 K G AA L G AGG+ + T P + +K+++Q ++ G L +G Sbjct: 2 KSGPGIQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLR 61 Query: 482 GIYKGAKACFLRDIPFSAIYFPCYAHV-----KASFANEDGQVSPGSLLLAGAIAGMPAA 536 G YKG + + +++ F CY K + ++ ++S AG+ A AA Sbjct: 62 GFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAA 121 Query: 537 SLVTPADVIKTRLQV---------AARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 587 + P +++K RLQ A++ T +S V + IL+++GP + G + + Sbjct: 122 LALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVV----KGILKKDGPLGFYHGLSSTL 177 Query: 588 FRSSPQFGVTLLTYELLQRWF 608 + P + YEL + +F Sbjct: 178 LQEVPGYFFFFGGYELSRSFF 198 Score = 61.2 bits (147), Expect = 3e-09 Identities = 57/186 (30%), Positives = 85/186 (45%), Gaps = 23/186 (12%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNS--FDCFKKVLRYEGFFGLYR 393 GS A A A A+ P +LVK R+Q G++ ++ + K +L+ +G G Y Sbjct: 113 GSFASAFAALALCPTELVKCRLQTMYEM-EMSGKIAKSHNTIWSVVKGILKKDGPLGFYH 171 Query: 394 GLLPQLLGVAPEK-----AIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTN 448 GL LL P +L+ + F + + G V L +L+GG AG + Sbjct: 172 GLSSTLLQEVPGYFFFFGGYELSRSFFASGRSKDELGPVHL---MLSGGVAGICLWLVVF 228 Query: 449 PLEIVKIRLQV-------AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIY 501 P++ +K R+QV AG I T LSVVR+ G +Y G KA +R IP + Sbjct: 229 PVDCIKSRIQVLSMYGKQAGFIGT-----LLSVVRNEGIVALYSGLKATMIRAIPANGAL 283 Query: 502 FPCYAH 507 F Y + Sbjct: 284 FVAYEY 289 Score = 36.6 bits (83), Expect = 0.078 Identities = 34/121 (28%), Positives = 48/121 (39%), Gaps = 23/121 (19%) Query: 307 EAQRQQKASG---DSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRST 363 E R ASG D PV L ++ G VAG V+P+D +K+R+Q Sbjct: 192 ELSRSFFASGRSKDELGPVHLMLS--------GGVAGICLWLVVFPVDCIKSRIQVLSMY 243 Query: 364 GS---FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420 G F+G L+ V+R EG LY GL ++ P ++ R Sbjct: 244 GKQAGFIGTLL---------SVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMM 294 Query: 421 M 421 M Sbjct: 295 M 295 >gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] Length = 321 Score = 100 bits (248), Expect = 6e-21 Identities = 86/300 (28%), Positives = 133/300 (44%), Gaps = 36/300 (12%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRST-----------GSFVGELMYKNS------FDC 378 G G VGA P++++KTR+Q+ R G+ G M + + F Sbjct: 18 GGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQV 77 Query: 379 FKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGC 438 K +L EG L+RGL P L+GVAP +A+ +++F I + G Sbjct: 78 LKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGS 137 Query: 439 AGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRD 494 A NP+ +VK R+Q+ ++ +++ L R + G G Y+G A + Sbjct: 138 AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYA-G 196 Query: 495 IPFSAIYFPCYAHVK--------ASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADV 544 I + I F Y +K AS AN E S L+ A A++ A+ + P +V Sbjct: 197 ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEV 256 Query: 545 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604 I+TRL R T Y + R + REEG A ++G A++ R P + L TYEL+ Sbjct: 257 IRTRL----REEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELI 312 Score = 61.2 bits (147), Expect = 3e-09 Identities = 51/203 (25%), Positives = 87/203 (42%), Gaps = 32/203 (15%) Query: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQ------------------VAG-------EITTGP 467 + AGGC G IFT PLE++K RLQ ++G +T G Sbjct: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74 Query: 468 RVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLA 527 S++ G +++G + P A+YF CY+ K F +G P S ++ Sbjct: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF---NGIFVPNSNIVH 131 Query: 528 GAIAGMPA---ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 584 AG A SL+ P ++KTR+Q+ + + + C R + + EG + ++G Sbjct: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191 Query: 585 ARVFRSSPQFGVTLLTYELLQRW 607 A + + + YE L+++ Sbjct: 192 AS-YAGISETIICFAIYESLKKY 213 Score = 43.5 bits (101), Expect = 6e-04 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 21/105 (20%) Query: 525 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTY---------------------SGV 563 L AG G A P +VIKTRLQ + A +T Y G+ Sbjct: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74 Query: 564 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 608 + IL +EGPK+L++G G + +P V Y + F Sbjct: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119 >gi|115430257 solute carrier family 25, member 26 [Homo sapiens] Length = 274 Score = 99.0 bits (245), Expect = 1e-20 Identities = 75/255 (29%), Positives = 117/255 (45%), Gaps = 25/255 (9%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G VAG ++P+D +KTR+Q+ + F K GF G+Y G+ Sbjct: 13 GGVAGVSVDLILFPLDTIKTRLQSPQG----------------FNKA---GGFHGIYAGV 53 Query: 396 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA--EILAGGCAGGSQVIFTNPLEIV 453 +G P A ++V+ F+H D S L +LA + P E+V Sbjct: 54 PSAAIGSFPNAAAFFITYEYVK-WFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVV 112 Query: 454 KIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFA 513 K R QV+ T S +++ + G G+Y+G K+ LR+IPFS + FP + +KA ++ Sbjct: 113 KQRAQVSASTRTFQIFS--NILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWS 170 Query: 514 -NEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILR 572 +D V + GA AG AA++ TP DV KTR+ +A T V+ + R Sbjct: 171 WRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTADGNVLSVLHGVWR 230 Query: 573 EEGPKALWKGAGARV 587 +G L+ G R+ Sbjct: 231 SQGLAGLFAGVFPRM 245 Score = 64.7 bits (156), Expect = 3e-10 Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 18/163 (11%) Query: 431 AEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKAC 490 A ++AGG AG S + PL+ +K RLQ S + GF GIY G + Sbjct: 8 AALVAGGVAGVSVDLILFPLDTIKTRLQ-----------SPQGFNKAGGFHGIYAGVPSA 56 Query: 491 FLRDIPFSAIYFPCYAHVK-ASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRL 549 + P +A +F Y +VK A+ ++P +LA + + A + P++V+K R Sbjct: 57 AIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRA 116 Query: 550 QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSP 592 QV+A + F IL EEG + L++G + V R P Sbjct: 117 QVSAS------TRTFQIFSNILYEEGIQGLYRGYKSTVLREIP 153 Score = 30.8 bits (68), Expect = 4.3 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 16/84 (19%) Query: 525 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 584 L+AG +AG+ ++ P D IKTRLQ + + G ++ G Sbjct: 10 LVAGGVAGVSVDLILFPLDTIKTRLQSP---------------QGFNKAGGFHGIYAGVP 54 Query: 585 ARVFRSSPQFGVTLLTYELLQRWF 608 + S P +TYE + +WF Sbjct: 55 SAAIGSFPNAAAFFITYEYV-KWF 77 >gi|21389315 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 precursor [Homo sapiens] Length = 311 Score = 98.6 bits (244), Expect = 2e-20 Identities = 78/277 (28%), Positives = 134/277 (48%), Gaps = 20/277 (7%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQ-NQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRG 394 G +AG + +P + VKT++Q ++RS Y+ DC ++ +R G GLYRG Sbjct: 32 GGLAGGIEICITFPTEYVKTQLQLDERSHPP-----RYRGIGDCVRQTVRSHGVLGLYRG 86 Query: 395 LLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ-VIFTNPLEIV 453 L L G P+ A++ + +F+ + G + +L G AG ++ V+ P+E + Sbjct: 87 LSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETI 146 Query: 454 KIRLQVAGEITTGPRVSAL-----SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHV 508 K++ + + + P+ +VR+ G G Y+G A L+ AI F + Sbjct: 147 KVKF-IHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSL 205 Query: 509 KASFA--NEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ-VAARAGQTTYSGVID 565 + + N + ++P + GAIAG + TP DVIKTR+Q + A + T+ D Sbjct: 206 RNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTW----D 261 Query: 566 CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602 C +IL++EG KA +KG R+ R + + Y+ Sbjct: 262 CGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYD 298 Score = 74.7 bits (182), Expect = 3e-13 Identities = 52/182 (28%), Positives = 82/182 (45%), Gaps = 7/182 (3%) Query: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALS-----VVRDLGFFGIYKGA 487 ILAGG AGG ++ T P E VK +LQ+ E + PR + VR G G+Y+G Sbjct: 29 ILAGGLAGGIEICITFPTEYVKTQLQL-DERSHPPRYRGIGDCVRQTVRSHGVLGLYRGL 87 Query: 488 KACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVT-PADVIK 546 + IP +A+ F + + + G++ LL G AG+ A +V P + IK Sbjct: 88 SSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIK 147 Query: 547 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606 + + Y G R+I+RE+G K ++G A V + + L+ Sbjct: 148 VKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRN 207 Query: 607 WF 608 W+ Sbjct: 208 WY 209 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/84 (32%), Positives = 45/84 (53%) Query: 521 PGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALW 580 PG +LAG +AG + P + +KT+LQ+ R+ Y G+ DC R+ +R G L+ Sbjct: 25 PGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLY 84 Query: 581 KGAGARVFRSSPQFGVTLLTYELL 604 +G + ++ S P+ V +E L Sbjct: 85 RGLSSLLYGSIPKAAVRFGMFEFL 108 Score = 50.1 bits (118), Expect = 7e-06 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 7/81 (8%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G++AGA P+D++KTRMQ + Y+N++DC ++L+ EG Y+G Sbjct: 227 GAIAGAASVFGNTPLDVIKTRMQGLEAH-------KYRNTWDCGLQILKKEGLKAFYKGT 279 Query: 396 LPQLLGVAPEKAIKLTVNDFV 416 +P+L V + AI + D V Sbjct: 280 VPRLGRVCLDVAIVFVIYDEV 300 >gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo sapiens] Length = 325 Score = 98.6 bits (244), Expect = 2e-20 Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 7/280 (2%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQ-RSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 391 F G +A V +P+DL KTR+Q Q +S + E+ Y+ F ++ + EG L Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103 Query: 392 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 451 Y G+ P LL A IK+ + ++ F+ + L ++ G +G NP + Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163 Query: 452 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 510 ++KIR+Q G + G + S + + + G G+++G R + P Y K Sbjct: 164 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223 Query: 511 SFANEDGQVSPGSL--LLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 566 G + L ++ G+ A P DV++TR+ Q A Y G +D Sbjct: 224 HLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 282 Query: 567 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606 K+ + EG AL+KG R P + +TYE L+R Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322 Score = 46.2 bits (108), Expect = 1e-04 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 6/132 (4%) Query: 482 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 541 GI+ G FLR + F+ H K++ + + + G +A + A P Sbjct: 2 GIFPGIILIFLR-VKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60 Query: 542 ADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGV 596 D+ KTRLQV AR + Y G+ +I +EEG AL+ G + R + + Sbjct: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120 Query: 597 TLLTYELLQRWF 608 + Y+ L+R F Sbjct: 121 KIGIYQSLKRLF 132 >gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo sapiens] Length = 322 Score = 98.6 bits (244), Expect = 2e-20 Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 7/280 (2%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQ-RSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 391 F G +A V +P+DL KTR+Q Q +S + E+ Y+ F ++ + EG L Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100 Query: 392 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 451 Y G+ P LL A IK+ + ++ F+ + L ++ G +G NP + Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 160 Query: 452 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 510 ++KIR+Q G + G + S + + + G G+++G R + P Y K Sbjct: 161 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 220 Query: 511 SFANEDGQVSPGSL--LLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 566 G + L ++ G+ A P DV++TR+ Q A Y G +D Sbjct: 221 HLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 279 Query: 567 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606 K+ + EG AL+KG R P + +TYE L+R Sbjct: 280 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319 Score = 43.5 bits (101), Expect = 6e-04 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 9/132 (6%) Query: 482 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 541 GI+ G FLR + F+ H K++ + + + G +A + A P Sbjct: 2 GIFPGIILIFLR-VKFATA---AVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 57 Query: 542 ADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGV 596 D+ KTRLQV AR + Y G+ +I +EEG AL+ G + R + + Sbjct: 58 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 117 Query: 597 TLLTYELLQRWF 608 + Y+ L+R F Sbjct: 118 KIGIYQSLKRLF 129 >gi|149274643 solute carrier family 25, member 28 [Homo sapiens] Length = 364 Score = 97.8 bits (242), Expect = 3e-20 Identities = 77/279 (27%), Positives = 122/279 (43%), Gaps = 16/279 (5%) Query: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 G+VAG + +YPID VKTRMQ+ + + Y+N + +++R EG + RGL Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQPDPA----ARYRNVLEALWRIIRTEGLWRPMRGL 134 Query: 396 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIF----TNPLE 451 G P A+ + ++ D P +A G AG + NP E Sbjct: 135 NVTATGAGPAHALYFACYEKLKKTL--SDVIHPGGNSHIANGAAGCVATLLHDAAMNPAE 192 Query: 452 IVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKAS 511 +VK R+Q+ +V ++ G Y+ ++PF AI+F Y ++ Sbjct: 193 VVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEH 252 Query: 512 FANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTY-----SGVIDC 566 F N + +P S +L+GA AG AA+ TP DV KT L ++ +G+ Sbjct: 253 F-NPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASA 311 Query: 567 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 605 FR + + G A ++G ARV P + YE + Sbjct: 312 FRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFK 350 Score = 58.5 bits (140), Expect = 2e-08 Identities = 45/189 (23%), Positives = 84/189 (44%), Gaps = 16/189 (8%) Query: 429 LAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALS----VVRDLGFFGIY 484 + ++AG AG + P++ VK R+Q + L ++R G + Sbjct: 72 VTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPM 131 Query: 485 KGAKACFLRDIPFSAIYFPCYAHVKASFANE-----DGQVSPGSLLLAGAIAGMPAASLV 539 +G P A+YF CY +K + ++ + ++ G+ AG +A + + + Sbjct: 132 RGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGA---AGCVATLLHDAAM 188 Query: 540 TPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 599 PA+V+K R+Q+ + Y V DC R + + EG A ++ ++ + P + + Sbjct: 189 NPAEVVKQRMQMY----NSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFM 244 Query: 600 TYELLQRWF 608 TYE LQ F Sbjct: 245 TYEFLQEHF 253 >gi|7706306 solute carrier family 25, member 39 isoform b [Homo sapiens] Length = 351 Score = 96.7 bits (239), Expect = 6e-20 Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 10/246 (4%) Query: 372 YKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA 431 + + D F K++R+EG L+ GL L+ P AI T D ++ + + L A Sbjct: 96 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 155 Query: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 491 ++AG A V +PLE+++ +LQ + V G+ ++ G Sbjct: 156 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 215 Query: 492 LRDIPFSAIYFPCYAHVKA---SFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 548 LRD+PFSA+Y+ Y VK+ F +D Q S G +AG I+G AA L P DV+KT+ Sbjct: 216 LRDVPFSALYWFNYELVKSWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 274 Query: 549 LQVAARAGQTTYSGVID------CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602 QVA A + + R+I E G K L+ G R+ +++P + + TYE Sbjct: 275 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334 Query: 603 LLQRWF 608 + +F Sbjct: 335 FGKSFF 340 Score = 43.1 bits (100), Expect = 8e-04 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF----VGELMYKNSFDCFKKVLRYEGF 388 F G ++G V A P D+VKT Q Q + G+ V L +++ +++ G Sbjct: 251 FVAGGISGTVAAVLTLPFDVVKT--QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGT 308 Query: 389 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420 GL+ G LP+++ AP AI ++ +F + F Sbjct: 309 KGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 340 Score = 37.7 bits (86), Expect = 0.035 Identities = 16/48 (33%), Positives = 26/48 (54%) Query: 558 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 605 T ++G +D F KI+R EG + LW G A + + P + Y+ L+ Sbjct: 94 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 141 >gi|219555665 solute carrier family 25, member 39 isoform a [Homo sapiens] Length = 359 Score = 96.7 bits (239), Expect = 6e-20 Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 10/246 (4%) Query: 372 YKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA 431 + + D F K++R+EG L+ GL L+ P AI T D ++ + + L A Sbjct: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163 Query: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 491 ++AG A V +PLE+++ +LQ + V G+ ++ G Sbjct: 164 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 223 Query: 492 LRDIPFSAIYFPCYAHVKA---SFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 548 LRD+PFSA+Y+ Y VK+ F +D Q S G +AG I+G AA L P DV+KT+ Sbjct: 224 LRDVPFSALYWFNYELVKSWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282 Query: 549 LQVAARAGQTTYSGVID------CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602 QVA A + + R+I E G K L+ G R+ +++P + + TYE Sbjct: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342 Query: 603 LLQRWF 608 + +F Sbjct: 343 FGKSFF 348 Score = 43.1 bits (100), Expect = 8e-04 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF----VGELMYKNSFDCFKKVLRYEGF 388 F G ++G V A P D+VKT Q Q + G+ V L +++ +++ G Sbjct: 259 FVAGGISGTVAAVLTLPFDVVKT--QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGT 316 Query: 389 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420 GL+ G LP+++ AP AI ++ +F + F Sbjct: 317 KGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 348 Score = 37.7 bits (86), Expect = 0.035 Identities = 16/48 (33%), Positives = 26/48 (54%) Query: 558 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 605 T ++G +D F KI+R EG + LW G A + + P + Y+ L+ Sbjct: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149 >gi|27544933 solute carrier family 25, member 16 [Homo sapiens] Length = 332 Score = 96.3 bits (238), Expect = 8e-20 Identities = 79/299 (26%), Positives = 132/299 (44%), Gaps = 26/299 (8%) Query: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392 F G +AG T V P+D VK +Q +G F + V + EGF GLY Sbjct: 40 FLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGV------FSALRAVPQKEGFLGLY 93 Query: 393 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEI 452 +G ++ + P AI+ + + K G ++AG AG + VI T PL++ Sbjct: 94 KGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDM 153 Query: 453 VKIRL--QVAGEITTGPRVSALSVV--RDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHV 508 V++RL QV GE + + A + ++ GFFG Y+G L P++ + F + + Sbjct: 154 VRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTL 213 Query: 509 KA-------SFANEDGQVSPGSL-------LLAGAIAGMPAASLVTPADVIKTRLQVAAR 554 K+ + +P L LL G +AG A ++ P DV + R+Q+ Sbjct: 214 KSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTV 273 Query: 555 AGQTTYSGVI-DCFRKILREEG-PKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYID 611 + + D + + G K L++G R P V TYEL++++F+++ Sbjct: 274 LPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN 332 Score = 70.1 bits (170), Expect = 6e-12 Identities = 55/213 (25%), Positives = 88/213 (41%), Gaps = 32/213 (15%) Query: 324 LQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVL 383 L ++ +R GS+AG YP+D+V+ R+ Q GE Y FK + Sbjct: 125 LGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQ-----VKGEHSYTGIIHAFKTIY 179 Query: 384 RYE-GFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRD-------KFMHKDGS-------VP 428 E GFFG YRGL+P +LG+AP + ++ + + S + Sbjct: 180 AKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLK 239 Query: 429 LAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFF------- 481 +L GG AG + P ++ + R+Q+ T P +RD + Sbjct: 240 THVNLLCGGVAGAIAQTISYPFDVTRRRMQLG---TVLPEFEKCLTMRDTMKYVYGHHGI 296 Query: 482 --GIYKGAKACFLRDIPFSAIYFPCYAHVKASF 512 G+Y+G ++R IP A+ F Y +K F Sbjct: 297 RKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFF 329 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,884,441 Number of Sequences: 37866 Number of extensions: 1045501 Number of successful extensions: 2988 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 71 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 2193 Number of HSP's gapped (non-prelim): 255 length of query: 676 length of database: 18,247,518 effective HSP length: 109 effective length of query: 567 effective length of database: 14,120,124 effective search space: 8006110308 effective search space used: 8006110308 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.