Guide to the Human Genome
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Search of human proteins with 23397693

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
         (719 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397693 egf-like module containing, mucin-like, hormone rece...  1475   0.0  
gi|23397685 egf-like module containing, mucin-like, hormone rece...  1467   0.0  
gi|23397691 egf-like module containing, mucin-like, hormone rece...  1454   0.0  
gi|23397683 egf-like module containing, mucin-like, hormone rece...  1446   0.0  
gi|23397689 egf-like module containing, mucin-like, hormone rece...  1412   0.0  
gi|23397681 egf-like module containing, mucin-like, hormone rece...  1404   0.0  
gi|23397687 egf-like module containing, mucin-like, hormone rece...  1166   0.0  
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]           829   0.0  
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]           808   0.0  
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]           766   0.0  
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...   567   e-161
gi|40807489 egf-like module containing, mucin-like, hormone rece...   422   e-118
gi|148806925 EGF, latrophilin and seven transmembrane domain con...   269   8e-72
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     262   9e-70
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]          258   2e-68
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]          258   2e-68
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   250   3e-66
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...   206   5e-53
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...   189   1e-47
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]   185   1e-46
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]   185   1e-46
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]   185   1e-46
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]   185   1e-46
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             177   2e-44
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]             173   6e-43
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho...   166   7e-41
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom...   166   7e-41
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho...   166   7e-41
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom...   166   7e-41
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...   155   9e-38

>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score = 1475 bits (3819), Expect = 0.0
 Identities = 719/719 (100%), Positives = 719/719 (100%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180
           DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
Sbjct: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180

Query: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240
           HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL
Sbjct: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240

Query: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300
           LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK
Sbjct: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300

Query: 301 SGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSP 360
           SGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSP
Sbjct: 301 SGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSP 360

Query: 361 VTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 420
           VTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM
Sbjct: 361 VTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 420

Query: 421 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 480
           AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL
Sbjct: 421 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 480

Query: 481 LFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMK 540
           LFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMK
Sbjct: 481 LFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMK 540

Query: 541 KLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFL 600
           KLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFL
Sbjct: 541 KLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFL 600

Query: 601 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 660
           VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT
Sbjct: 601 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 660

Query: 661 IINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 719
           IINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN
Sbjct: 661 IINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 719


>gi|23397685 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform c [Homo sapiens]
          Length = 730

 Score = 1467 bits (3797), Expect = 0.0
 Identities = 719/730 (98%), Positives = 719/730 (98%), Gaps = 11/730 (1%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180
           DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
Sbjct: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180

Query: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240
           HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL
Sbjct: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240

Query: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300
           LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK
Sbjct: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300

Query: 301 SGDPG-----------MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL 349
           SGDPG           MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL
Sbjct: 301 SGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL 360

Query: 350 SNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 409
           SNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR
Sbjct: 361 SNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 420

Query: 410 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 469
           CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL
Sbjct: 421 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 480

Query: 470 QLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTV 529
           QLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTV
Sbjct: 481 QLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTV 540

Query: 530 VNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVC 589
           VNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVC
Sbjct: 541 VNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVC 600

Query: 590 AIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVG 649
           AIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVG
Sbjct: 601 AIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVG 660

Query: 650 PAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAK 709
           PAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAK
Sbjct: 661 PAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAK 720

Query: 710 ADTSKPSTVN 719
           ADTSKPSTVN
Sbjct: 721 ADTSKPSTVN 730


>gi|23397691 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform f [Homo sapiens]
          Length = 763

 Score = 1454 bits (3764), Expect = 0.0
 Identities = 719/763 (94%), Positives = 719/763 (94%), Gaps = 44/763 (5%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 121 DEC--------------------------------------------SSGQHQCDSSTVC 136
           DEC                                            SSGQHQCDSSTVC
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDSSTVC 180

Query: 137 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 196
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 181 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 197 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 256
           RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300

Query: 257 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKLLAEAPLV 316
           NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKLLAEAPLV
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKLLAEAPLV 360

Query: 317 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV 376
           LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV
Sbjct: 361 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV 420

Query: 377 LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVIT 436
           LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVIT
Sbjct: 421 LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVIT 480

Query: 437 YMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCS 496
           YMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCS
Sbjct: 481 YMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCS 540

Query: 497 IIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVA 556
           IIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVA
Sbjct: 541 IIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVA 600

Query: 557 ISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSE 616
           ISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSE
Sbjct: 601 ISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSE 660

Query: 617 VSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCL 676
           VSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCL
Sbjct: 661 VSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCL 720

Query: 677 LSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 719
           LSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN
Sbjct: 721 LSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 763


>gi|23397683 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform b [Homo sapiens]
          Length = 774

 Score = 1446 bits (3742), Expect = 0.0
 Identities = 719/774 (92%), Positives = 719/774 (92%), Gaps = 55/774 (7%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQ-- 118
           PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQ  
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 119 ------------------------------------------DVDECSSGQHQCDSSTVC 136
                                                     DVDECSSGQHQCDSSTVC
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDSSTVC 180

Query: 137 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 196
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 181 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 197 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 256
           RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300

Query: 257 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGD-----------PG 305
           NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGD           PG
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPG 360

Query: 306 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 365
           MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF
Sbjct: 361 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 420

Query: 366 SHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDV 425
           SHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDV
Sbjct: 421 SHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDV 480

Query: 426 QEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVA 485
           QEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVA
Sbjct: 481 QEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVA 540

Query: 486 IDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFP 545
           IDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFP
Sbjct: 541 IDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFP 600

Query: 546 VGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWI 605
           VGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWI
Sbjct: 601 VGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWI 660

Query: 606 LKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSL 665
           LKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSL
Sbjct: 661 LKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSL 720

Query: 666 QGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 719
           QGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN
Sbjct: 721 QGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 774


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score = 1412 bits (3655), Expect = 0.0
 Identities = 710/812 (87%), Positives = 713/812 (87%), Gaps = 93/812 (11%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 121 D--------------------------------------------ECSSGQHQCDSSTVC 136
           D                                            EC+SGQ+ C SST C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180

Query: 137 FNTVGSYSCRCRPGWKP------------------------------------------- 153
            N VGSY CRCRPGW+P                                           
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240

Query: 154 ------RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 207
                 RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT
Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300

Query: 208 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 267
           IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG
Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360

Query: 268 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKLLAEAPLVLEPEKQMLLHE 327
           TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKLLAEAPLVLEPEKQMLLHE
Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKLLAEAPLVLEPEKQMLLHE 420

Query: 328 THQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNG 387
           THQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNG
Sbjct: 421 THQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNG 480

Query: 388 CGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCL 447
           CGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCL
Sbjct: 481 CGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCL 540

Query: 448 LLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYL 507
           LLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYL
Sbjct: 541 LLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYL 600

Query: 508 ATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYG 567
           ATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYG
Sbjct: 601 ATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYG 660

Query: 568 TPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLA 627
           TPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLA
Sbjct: 661 TPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLA 720

Query: 628 FKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK 687
           FKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK
Sbjct: 721 FKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK 780

Query: 688 WSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 719
           WSKGIRKLKTESEMHTLSSSAKADTSKPSTVN
Sbjct: 781 WSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 812


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 1404 bits (3633), Expect = 0.0
 Identities = 710/823 (86%), Positives = 713/823 (86%), Gaps = 104/823 (12%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 121 D--------------------------------------------ECSSGQHQCDSSTVC 136
           D                                            EC+SGQ+ C SST C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180

Query: 137 FNTVGSYSCRCRPGWKP------------------------------------------- 153
            N VGSY CRCRPGW+P                                           
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240

Query: 154 ------RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 207
                 RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT
Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300

Query: 208 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 267
           IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG
Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360

Query: 268 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGD-----------PGMGKLLAEAPLV 316
           TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGD           PGMGKLLAEAPLV
Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLV 420

Query: 317 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV 376
           LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV
Sbjct: 421 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV 480

Query: 377 LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVIT 436
           LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVIT
Sbjct: 481 LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVIT 540

Query: 437 YMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCS 496
           YMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCS
Sbjct: 541 YMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCS 600

Query: 497 IIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVA 556
           IIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVA
Sbjct: 601 IIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVA 660

Query: 557 ISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSE 616
           ISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSE
Sbjct: 661 ISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSE 720

Query: 617 VSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCL 676
           VSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCL
Sbjct: 721 VSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCL 780

Query: 677 LSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 719
           LSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN
Sbjct: 781 LSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN 823


>gi|23397687 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform d [Homo sapiens]
          Length = 681

 Score = 1166 bits (3016), Expect = 0.0
 Identities = 605/733 (82%), Positives = 620/733 (84%), Gaps = 66/733 (9%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFLVFLAFCVWLTL                                          
Sbjct: 1   MGGRVFLVFLAFCVWLTL------------------------------------------ 18

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           P     D   CA      C + S C N      C C+PG+   S   T   E   TC D+
Sbjct: 19  PGAETQDSRGCARW----CPQDSSCVNATA---CRCNPGFSSFSEIITTPME---TCDDI 68

Query: 121 DECSS-GQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPN--NQKDTVCEDMTFSTWTPP 177
           +EC++  +  C   + C+NT GSY C C PG++P  G     N+ +  C+DMTFSTWTPP
Sbjct: 69  NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFSTWTPP 128

Query: 178 PGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVA 237
           PGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVA
Sbjct: 129 PGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVA 188

Query: 238 SHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQ 297
           SHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQ
Sbjct: 189 SHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQ 248

Query: 298 AQKSGDPG-----------MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVIS 346
           AQKSGDPG           MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVIS
Sbjct: 249 AQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVIS 308

Query: 347 AFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTST 406
           AFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTST
Sbjct: 309 AFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTST 368

Query: 407 ICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTS 466
           ICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTS
Sbjct: 369 ICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTS 428

Query: 467 LHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARN 526
           LHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARN
Sbjct: 429 LHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARN 488

Query: 527 LTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG 586
           LTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG
Sbjct: 489 LTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG 548

Query: 587 PVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGIL 646
           PVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGIL
Sbjct: 549 PVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGIL 608

Query: 647 QVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSS 706
           QVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSS
Sbjct: 609 QVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSS 668

Query: 707 SAKADTSKPSTVN 719
           SAKADTSKPSTVN
Sbjct: 669 SAKADTSKPSTVN 681


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score =  829 bits (2142), Expect = 0.0
 Identities = 413/718 (57%), Positives = 511/718 (71%), Gaps = 39/718 (5%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117

Query: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180
           DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
Sbjct: 118 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 177

Query: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240
           HSQTLSRFFDKVQDLGRD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ L
Sbjct: 178 HSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQL 237

Query: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300
           L  LED++R L+K+L  G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  
Sbjct: 238 LSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAG 297

Query: 301 SGDPG-----------MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL 349
           + DPG           M  LLA A L L  +KQ  L E ++  ++      LS V S FL
Sbjct: 298 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL 357

Query: 350 SNNDTQNLSSPVTFTFSH--------------RSVI--PRQKVLCVFWEHGQNGCGHWAT 393
           S+N+T+ L+SP+ F FSH              + V+  PRQ++LC FW+   +  GHWAT
Sbjct: 358 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT 417

Query: 394 TGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALT 453
            GC  +G+++ ST C+C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LT
Sbjct: 418 EGCQVLGSKNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILT 475

Query: 454 FLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLT 511
           FLL + IQ + T++HL L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   
Sbjct: 476 FLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFC 535

Query: 512 WMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSR 571
           WM LE L L+       VV          + +  +GYGVP + V +SAA     YG P  
Sbjct: 536 WMSLEGLELY-----FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRY 590

Query: 572 CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKAT 631
           CWL  E+GF+W FLGPV  I   N V+F+ T+W L  + S +N ++  L+  R L   A 
Sbjct: 591 CWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI 650

Query: 632 AQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 689
           AQLF+LGCTW  G+      + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 651 AQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score =  808 bits (2087), Expect = 0.0
 Identities = 413/762 (54%), Positives = 511/762 (67%), Gaps = 83/762 (10%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117

Query: 121 DEC--------------------------------------------SSGQHQCDSSTVC 136
           DEC                                            SSGQHQCDSSTVC
Sbjct: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVC 177

Query: 137 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 196
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 178 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 237

Query: 197 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 256
           RD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L 
Sbjct: 238 RDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLP 297

Query: 257 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG----------- 305
            G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG           
Sbjct: 298 KGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 357

Query: 306 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 365
           M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F F
Sbjct: 358 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF 417

Query: 366 SH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 409
           SH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+
Sbjct: 418 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ 477

Query: 410 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 469
           C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL
Sbjct: 478 CSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL 535

Query: 470 QLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNL 527
            L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+      
Sbjct: 536 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----F 590

Query: 528 TVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGP 587
            VV          + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGP
Sbjct: 591 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 650

Query: 588 VCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQ 647
           V  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+  
Sbjct: 651 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 710

Query: 648 VGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 689
               + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 711 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 752


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score =  766 bits (1978), Expect = 0.0
 Identities = 404/811 (49%), Positives = 505/811 (62%), Gaps = 132/811 (16%)

Query: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57

Query: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117

Query: 121 D--------------------------------------------ECSSGQHQCDSSTVC 136
           D                                            EC+SGQ+ C SST C
Sbjct: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177

Query: 137 FNTVGSYSCRCRPGWKP------------------------------------------- 153
            N VGSY CRCRPGW+P                                           
Sbjct: 178 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237

Query: 154 ------RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 207
                 RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K   A  T
Sbjct: 238 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 297

Query: 208 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 267
           IQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L  G   +  P+ 
Sbjct: 298 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 357

Query: 268 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG-----------MGKLLAEAPLV 316
           TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG           M  LLA A L 
Sbjct: 358 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 417

Query: 317 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 367
           L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F FSH         
Sbjct: 418 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 477

Query: 368 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 420
                + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+C+HLSSFA+LM
Sbjct: 478 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 537

Query: 421 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 480
           AHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL L +CLF+   
Sbjct: 538 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 595

Query: 481 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 538
           +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+       VV        
Sbjct: 596 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 650

Query: 539 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 598
             + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGPV  I   N V+
Sbjct: 651 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 710

Query: 599 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 658
           F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+      + V+ Y+
Sbjct: 711 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 770

Query: 659 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 689
           FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 771 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score =  567 bits (1461), Expect = e-161
 Identities = 337/654 (51%), Positives = 412/654 (62%), Gaps = 50/654 (7%)

Query: 75  SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH-QCDSS 133
           +K SC K     +   +  C C+ GY   SG K F    E TC D++EC+      C  +
Sbjct: 24  TKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLE-TCNDINECTPPYSVYCGFN 82

Query: 134 TVCFNTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDK 191
            VC+N  GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK
Sbjct: 83  AVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDK 138

Query: 192 VQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPR-LQQHCVASHLLDGLEDVLRG 250
            + L       L N T    L   +   E      T+ R ++   + + L D  + VL+ 
Sbjct: 139 FESL-------LTNQT----LWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLK- 186

Query: 251 LSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGMGKL- 309
               + N  +     A T+   E +K  + +V +  +  +   D  Q    G   +  + 
Sbjct: 187 ----IQNDSVAIETQAITDNCSEERKTFNLNVQMN-SMDIRCSDIIQGDTQGPSAIAFIS 241

Query: 310 ------LAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTF 363
                 +  A    E +K+  ++             L S V+SA +      +LS  VT 
Sbjct: 242 YSSLGNIINATFFEEMDKKDQVY-------------LNSQVVSAAIGPKRNVSLSKSVTL 288

Query: 364 TFSHRSVIPR-QKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAH 422
           TF H  + P  +KV CV+W+    G   W+  GC  I    + T+C C+HLSSFAVLMA 
Sbjct: 289 TFQHVKMTPSTKKVFCVYWKSTGQG-SQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA- 346

Query: 423 YDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLF 482
              QEEDPVLTVITY+GLSVSLLCLLLAALTFLLCKAI+NTSTSLHLQLSLCLFLAHLLF
Sbjct: 347 LTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLF 406

Query: 483 LVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKL 542
           LV ID+T  KVLCSIIAG LHYLYLA  TWMLLE ++LFLTARNLTVVNYSSINR MK +
Sbjct: 407 LVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWI 466

Query: 543 MFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVT 602
           MFPVGYGVPAVTVAISAAS PHLYGT  RCWL  ++GF+W FLGPVCAIFS NLVLF++ 
Sbjct: 467 MFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILV 526

Query: 603 LWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTII 662
            WILK +LSSLNSEVST++NTRMLAFKATAQLFILGCTWCLG+LQVGPAA+VMAYLFTII
Sbjct: 527 FWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTII 586

Query: 663 NSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPS 716
           NSLQG FIFLVYCLLSQQV++QY KW + I K K+ESE +TLSS    D SKPS
Sbjct: 587 NSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPD-SKPS 639



 Score =  110 bits (275), Expect = 5e-24
 Identities = 54/115 (46%), Positives = 71/115 (61%), Gaps = 2/115 (1%)

Query: 7   LVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFS--EIITTPMET 64
           L+    C  L+L GA TQ ++     CP ++SCVN T C CN G++S S  ++ T P+ET
Sbjct: 5   LLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLET 64

Query: 65  CDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 119
           C+DINEC     V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 65  CNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score =  422 bits (1085), Expect = e-118
 Identities = 260/732 (35%), Positives = 385/732 (52%), Gaps = 59/732 (8%)

Query: 24  QDSRGCA--RWCPQDSSCVNAT---ACRCNPGFSSFSEIITTP--METCDDINECATLSK 76
           +D   CA  R CP+ ++C N     +C CNPGF S S  ++      +C+DI+EC  +  
Sbjct: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230

Query: 77  VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVC 136
           ++    S C NT GSY C C PG+ P +G   F ++    C+D+DEC      C  +++C
Sbjct: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSIC 285

Query: 137 FNTVGSYSCRC------RPGWKPRHG---------------IPNNQKDTVCEDMTFSTWT 175
            N +GSYSC C       P    + G               IP+N++   C++ T     
Sbjct: 286 TNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGT--AVK 343

Query: 176 PPPGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHC 235
           P        ++  F  +  +  +        T+ S+    +  +     + T  +  +  
Sbjct: 344 PAYVSFCAQINNIFSVLDKVCEN------KTTVVSLKNTTESFVPVLKQISTWTKFTKEE 397

Query: 236 VASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV----- 290
            +S     LE V      +      N +    TE  L+++ +V       +N  +     
Sbjct: 398 TSSLATVFLESVESMTLASFWKPSANITPAVRTEY-LDIESKVINKECSEENVTLDLVAK 456

Query: 291 ---MQLDWNQAQKSGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL--SDVI 345
              M++  +  ++S       +   + + +E        + HQ  L      L   S V+
Sbjct: 457 GDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVV 516

Query: 346 SAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV---LCVFWEHGQNGCGHWATTGCSTIGTR 402
              ++       S P+ +T  +  + P+QK    +CV W     G G W + GC  +   
Sbjct: 517 GGIMTGEKKDGFSDPIIYTLEN--IQPKQKFERPICVSWSTDVKG-GRWTSFGCVILEAS 573

Query: 403 DTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQN 462
           +T TIC C  +++ AV+MA  ++   D  L +I+++G+ +SL+CL+LA  TFLLC++I+N
Sbjct: 574 ETYTICSCNQMANLAVIMASGELTM-DFSLYIISHVGIIISLVCLVLAIATFLLCRSIRN 632

Query: 463 TSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFL 522
            +T LHL L +CL LA  LFL  I +T +K+ C+IIAG LHYL+LA   WML+EA+ LFL
Sbjct: 633 HNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFL 692

Query: 523 TARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIW 582
             RNL VVNY S        +   GYG+P + V ISA+ +P  YG  +RCWL  E GFIW
Sbjct: 693 MVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIW 752

Query: 583 GFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWC 642
            FLGPVC +  +N +L   TLWIL+ RLSS+N+EVSTL++TR+L FKA AQLFILGC+W 
Sbjct: 753 SFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWV 812

Query: 643 LGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMH 702
           LGI Q+GP A VMAYLFTIINSLQG FIFL++CLL+ QVRE+Y +W  G  K  ++S+  
Sbjct: 813 LGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTS 872

Query: 703 TLSSSAKADTSK 714
            +  S+    SK
Sbjct: 873 RILLSSMPSASK 884



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 59/162 (36%), Positives = 78/162 (48%), Gaps = 24/162 (14%)

Query: 19  PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
           PG   +D   C++    C  +SSC N +    C C  GFSS +     P +    +C DI
Sbjct: 74  PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133

Query: 69  NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 128
           NEC T S   C + SDC N+ GSY C C  G+              +TC+DVDEC+    
Sbjct: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDECAD-PR 180

Query: 129 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQ-KDTVCEDM 169
            C     C NTVG+YSC C PG++   G  + Q     CED+
Sbjct: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)

Query: 79  CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 138
           C  ++ C NT  SY C C  G+   +G   FK+     C+D+DECS     C  ++ C N
Sbjct: 41  CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99

Query: 139 TVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 169
             G Y C C  G+    G   +P    +  C D+
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 32/87 (36%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 21  AETQDSRGCARWCPQDSSCVNATA---CRCNPGF--SSFSEIITTPMETCDDINECATLS 75
           A  +D   C   CP +S+C N      C C+PGF  S+     T     C DI+EC    
Sbjct: 217 ASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQ-D 275

Query: 76  KVSCGKFSDCWNTEGSYDCVCSPGYEP 102
             +CG  S C N  GSY C C  G+ P
Sbjct: 276 PSTCGPNSICTNALGSYSCGCIAGFHP 302


>gi|148806925 EGF, latrophilin and seven transmembrane domain
           containing 1 [Homo sapiens]
          Length = 690

 Score =  269 bits (687), Expect = 8e-72
 Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)

Query: 340 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 397
           ++S VIS  +S+N  T      +TFT SHR V  R + LC FW +  +   G W++ GC 
Sbjct: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390

Query: 398 TIGTRDTSTICRCTHLSSFAVLMAH---YDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 454
              + +T T CRC HL+ FA+LM+      +++ + +LT IT +G+ +SL+CL +   TF
Sbjct: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449

Query: 455 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 514
                IQ+T T++H  L   LFLA L+FLV I+   +K+ CSIIAG LHY +LA   WM 
Sbjct: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509

Query: 515 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 574
           +E ++L+L      VV       F+ K  +  GY  PAV V  SAA     YGT   CWL
Sbjct: 510 IEGIHLYLI-----VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564

Query: 575 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 634
             E  FIW F+GP C I  VNL+ F V ++ +    + L  EVS   N R  A  A A L
Sbjct: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624

Query: 635 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 692
           F+LG TW  G+L V  A+ V AYLFT+ N+ QG+FIFL  C+LS++++E+Y +  K +
Sbjct: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)

Query: 44  ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
           AC CN GFS     I      C+D NEC  L++ SCG+ ++C NTEGSY C+C PG+   
Sbjct: 41  ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93

Query: 104 SGAKTFKNESENTC 117
           S    F       C
Sbjct: 94  SNQDRFITNDGTVC 107



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 12/96 (12%)

Query: 57  IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
           ++ + +  C     C   +K  C   + C    G   C C+ G         F       
Sbjct: 8   VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55

Query: 117 CQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 152
           C+D +EC +    C  +  C NT GSY C C PG++
Sbjct: 56  CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFR 91


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  262 bits (669), Expect = 9e-70
 Identities = 182/551 (33%), Positives = 279/551 (50%), Gaps = 39/551 (7%)

Query: 191  KVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRL---QQHCVASHLLDGLEDV 247
            ++Q+L    K     +  ++I+  +D LL  P  LE+   +   +Q   A+ LLD LE+ 
Sbjct: 576  QLQELKPSEKDSAGRSYNKAIVDTVDNLLR-PEALESWKHMNSSEQAHTATMLLDTLEEG 634

Query: 248  LRGLSKNLSNGLLNFSYPAGT------ELSLEVQKQVDR-SVTLRQNQAVMQLDWNQAQK 300
               L+ NL       S P          LS E Q Q  +  + ++   + +QL  N  ++
Sbjct: 635  AFVLADNLLEPT-RVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAGSSIQLSANTVKQ 693

Query: 301  SGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLL------QDGSPILLSDVISAFLSNNDT 354
            +   G+ KL+    ++     Q L  E     L      ++ +  + S VIS  ++   +
Sbjct: 694  NSRNGLAKLVF---IIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESS 750

Query: 355  Q-NLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCSTIGTRDTSTICRCTH 412
            +  L+ PV FT  H          C FW + +    G+W+T GC  + T  T T C C+H
Sbjct: 751  RVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSH 810

Query: 413  LSSFAVLMAHYDVQEEDPV----LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLH 468
            L++FA+LMAH ++  +D V    LTVIT++G+ +SL+CL +   TF   + +Q+   ++H
Sbjct: 811  LTNFAILMAHREIAYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIH 870

Query: 469  LQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLT 528
              L + LF+A  +FL+ ID+T + + C I AG LH+ +LA   WM LE + L+L    + 
Sbjct: 871  KNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVF 930

Query: 529  VVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPV 588
               YS      KK  +  GY  PA  V +SAA     YGT   CWL  +  FIW F+GPV
Sbjct: 931  ESEYSR-----KKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPV 985

Query: 589  CAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQV 648
              I  +N++  ++TL  +    ++L  + S L N +     A A L +LG TW  G+L +
Sbjct: 986  TFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFI 1045

Query: 649  GPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGK---WSKGIRKLKTESEMHTLS 705
                 VMAYLFTI N+ QGVFIF+ +C L ++VR++YGK    S     L TES      
Sbjct: 1046 NEETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESP----H 1101

Query: 706  SSAKADTSKPS 716
            SS KA T++ S
Sbjct: 1102 SSVKASTTRTS 1112


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score =  258 bits (658), Expect = 2e-68
 Identities = 169/499 (33%), Positives = 260/499 (52%), Gaps = 24/499 (4%)

Query: 208  IQSILQALDELL--EAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYP 265
            I+++++ +D LL  EA    + +   +Q   A+ LLD LE+    L+ N+       +  
Sbjct: 617  IKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAK 676

Query: 266  AGTELSLEV---QKQVDRSVTLRQN---QAVMQLDWNQAQKSGDPGMGK----LLAEAPL 315
                L + V   + QV   V  ++    +  +QL     +++   G+ K    L     L
Sbjct: 677  ENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGL 736

Query: 316  VLEPEKQM--LLHETHQGLLQDGSPILLSDVISAFLSNNDTQN-LSSPVTFTFSHRSVIP 372
             L  E     L  E   G     S ++ S VI+A ++   ++  L  PV FT +H     
Sbjct: 737  FLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKN 796

Query: 373  RQKVLCVFWEHGQNGC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQE---E 428
                 C FW + +    G+W+T GC  + +  T T C C+HL++FAVLMAH ++ +    
Sbjct: 797  HFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRIN 856

Query: 429  DPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQ 488
            + +L+VIT++G+ +SL+CL +   TF   + +Q    ++H  L + LFLA LLFLV ID+
Sbjct: 857  ELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDK 916

Query: 489  TGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGY 548
            T +++ C I AG LHY +LA  +W+ LE ++L+L    +    YS       K  +  GY
Sbjct: 917  TQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRT-----KYYYLGGY 971

Query: 549  GVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKN 608
              PA+ V I+AA     YGT   CWL+ +  FIW F+GPV  +  VNLV  +VTL  +  
Sbjct: 972  CFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIR 1031

Query: 609  RLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGV 668
              S L  + S L N +  A  A A LF+LG TW  G+L +   + VMAYLFT  N+ QGV
Sbjct: 1032 SSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGV 1091

Query: 669  FIFLVYCLLSQQVREQYGK 687
            FIF+ +C L ++V ++Y K
Sbjct: 1092 FIFVFHCALQKKVHKEYSK 1110


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score =  258 bits (658), Expect = 2e-68
 Identities = 169/499 (33%), Positives = 260/499 (52%), Gaps = 24/499 (4%)

Query: 208  IQSILQALDELL--EAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYP 265
            I+++++ +D LL  EA    + +   +Q   A+ LLD LE+    L+ N+       +  
Sbjct: 612  IKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAK 671

Query: 266  AGTELSLEV---QKQVDRSVTLRQN---QAVMQLDWNQAQKSGDPGMGK----LLAEAPL 315
                L + V   + QV   V  ++    +  +QL     +++   G+ K    L     L
Sbjct: 672  ENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGL 731

Query: 316  VLEPEKQM--LLHETHQGLLQDGSPILLSDVISAFLSNNDTQN-LSSPVTFTFSHRSVIP 372
             L  E     L  E   G     S ++ S VI+A ++   ++  L  PV FT +H     
Sbjct: 732  FLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKN 791

Query: 373  RQKVLCVFWEHGQNGC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQE---E 428
                 C FW + +    G+W+T GC  + +  T T C C+HL++FAVLMAH ++ +    
Sbjct: 792  HFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRIN 851

Query: 429  DPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQ 488
            + +L+VIT++G+ +SL+CL +   TF   + +Q    ++H  L + LFLA LLFLV ID+
Sbjct: 852  ELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDK 911

Query: 489  TGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGY 548
            T +++ C I AG LHY +LA  +W+ LE ++L+L    +    YS       K  +  GY
Sbjct: 912  TQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRT-----KYYYLGGY 966

Query: 549  GVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKN 608
              PA+ V I+AA     YGT   CWL+ +  FIW F+GPV  +  VNLV  +VTL  +  
Sbjct: 967  CFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIR 1026

Query: 609  RLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGV 668
              S L  + S L N +  A  A A LF+LG TW  G+L +   + VMAYLFT  N+ QGV
Sbjct: 1027 SSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGV 1086

Query: 669  FIFLVYCLLSQQVREQYGK 687
            FIF+ +C L ++V ++Y K
Sbjct: 1087 FIFVFHCALQKKVHKEYSK 1105


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  250 bits (639), Expect = 3e-66
 Identities = 136/375 (36%), Positives = 210/375 (56%), Gaps = 22/375 (5%)

Query: 330  QGLLQDGSPILLSDVISAFLSNNDTQN--LSSPVTFTFSH-RSVIPRQKVLCVFWEHGQN 386
            + L  + S I+ S VI+A ++   +    L+ PV FT  H +         C FW + + 
Sbjct: 767  EALSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKR 826

Query: 387  GC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPV----LTVITYMGLS 441
               G+W+T GC  + T  T T C C HL++FAVLMAH +V+  D V    L VIT++G+ 
Sbjct: 827  TMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGIL 886

Query: 442  VSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGT 501
            +SL+CLL+   TF   + +Q+   ++H  L + LF+A LLFL+ I++T   + C++ A  
Sbjct: 887  LSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAAL 946

Query: 502  LHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAAS 561
            LH+ +LA  TWM LE + L+     + +V         +K  + VGYG+PA+ VA+SAA 
Sbjct: 947  LHFFFLAAFTWMFLEGVQLY-----IMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAV 1001

Query: 562  RPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLR 621
                YGT   CWL+ +  FIW F+GP   I  +N++   + L+ + +  + L  E   L 
Sbjct: 1002 DYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLD 1061

Query: 622  N---------TRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFL 672
            N          +     A A L +LG TW  G++ +  +  +MAYLFTI NSLQG+FIF+
Sbjct: 1062 NINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFI 1121

Query: 673  VYCLLSQQVREQYGK 687
             +C+L ++VR++YGK
Sbjct: 1122 FHCVLQKKVRKEYGK 1136


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score =  206 bits (525), Expect = 5e-53
 Identities = 124/378 (32%), Positives = 199/378 (52%), Gaps = 28/378 (7%)

Query: 338  PILLSDVISAFLSNNDT---QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQ--NGCGHWA 392
            PI+ + ++S  + +      + L  PV   F+   V  R K +CVFW H     G G W+
Sbjct: 2368 PIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWS 2427

Query: 393  TTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDP----VLTVITYMGLSVSLLCLL 448
              GC  +    T   C+C+H +SFAVLM   D+   +      L ++TY  +S+SL  LL
Sbjct: 2428 ARGCELLSRNRTHVACQCSHTASFAVLM---DISRRENGEVLPLKIVTYAAVSLSLAALL 2484

Query: 449  LAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLA 508
            +A +   L + +++   S+H  L++ LFL+ L+F++ I+QT +  LC+++A  LHY+Y++
Sbjct: 2485 VAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMS 2544

Query: 509  TLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGT 568
            T  W L+E+L+++   R LT V   +I+    +  + VG+G+PA+   ++    P  YG 
Sbjct: 2545 TFAWTLVESLHVY---RMLTEVR--NIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGN 2599

Query: 569  PSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWI---LKNRLSSLNSEVSTLRNTRM 625
            P  CWL  +   IW F GP+ A+  +N V  +++  +    K+        VS LR   +
Sbjct: 2600 PDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVLSAKVSCQRKHHYYGKKGIVSLLRTAFL 2659

Query: 626  LAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQY 685
            L       L ++  TW LG+L V   A    YLF I + LQG F+ L +C+L+Q+VR+  
Sbjct: 2660 L-------LLLISATWLLGLLAVNRDALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRKHL 2712

Query: 686  GKWSKGIRKLKTESEMHT 703
             K   G RKL  E    T
Sbjct: 2713 -KGVLGGRKLHLEDSATT 2729



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 23/112 (20%)

Query: 40   VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 99
            +N   CRC PGF+   +   T ++ C             CG    C + EG Y C C   
Sbjct: 1344 INGLRCRCPPGFT--GDYCETEIDLC---------YSDPCGANGRCRSREGGYTCEC--- 1389

Query: 100  YEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 150
                   + F  E          C++G   C +   C N  +G + C C PG
Sbjct: 1390 ------FEDFTGEHCEVDARSGRCANG--VCKNGGTCVNLLIGGFHCVCPPG 1433


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score =  189 bits (479), Expect = 1e-47
 Identities = 121/356 (33%), Positives = 181/356 (50%), Gaps = 23/356 (6%)

Query: 338  PILLSDVISAFLSNNDT---QNLSSPVTFTFSHRSVIPRQKVLCVFWEHG--QNGCGHWA 392
            PI+ + V+S  + +++    + L  PVT  F       R K +CVFW H    +G G W+
Sbjct: 2276 PIINTPVVSISVHDDEELLPRALDKPVTVQFRLLETEERTKPICVFWNHSILVSGTGGWS 2335

Query: 393  TTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDP----VLTVITYMGLSVSLLCLL 448
              GC  +   ++   C+C H++SFAVLM   DV   +      L  +TY+ L V+L  LL
Sbjct: 2336 ARGCEVVFRNESHVSCQCNHMTSFAVLM---DVSRRENGEILPLKTLTYVALGVTLAALL 2392

Query: 449  LAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLA 508
            L      L + +++    +   L+  L LA L+FL+ I+Q      C++IA  LH+LYL 
Sbjct: 2393 LTFFFLTLLRILRSNQHGIRRNLTAALGLAQLVFLLGINQADLPFACTVIAILLHFLYLC 2452

Query: 509  TLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGT 568
            T +W LLEAL+L+   R LT V    +N    +  + +G+GVPA    ++    P  YG 
Sbjct: 2453 TFSWALLEALHLY---RALTEVR--DVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGN 2507

Query: 569  PSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAF 628
            P  CWL      IW F GPV   F+V++ +F   L+IL  R S         +   +   
Sbjct: 2508 PDFCWLSIYDTLIWSFAGPVA--FAVSMSVF---LYILAARASCAAQRQGFEKKGPVSGL 2562

Query: 629  KAT-AQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVRE 683
            + + A L +L  TW L +L V     +  YLF   N +QG FIFL Y +LS++VR+
Sbjct: 2563 QPSFAVLLLLSATWLLALLSVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRK 2618



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 30/112 (26%), Positives = 39/112 (34%), Gaps = 23/112 (20%)

Query: 40   VNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPG 99
            V    CRC PGF+   +   T ++ C             CG    C + EG Y C+C  G
Sbjct: 1269 VGGLRCRCPPGFTG--DYCETEVDLC---------YSRPCGPHGRCRSREGGYTCLCRDG 1317

Query: 100  YEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 150
            Y           E          C+ G   C +   C N  VG + C C  G
Sbjct: 1318 Y---------TGEHCEVSARSGRCTPG--VCKNGGTCVNLLVGGFKCDCPSG 1358



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 114  ENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 151
            E  C   D C S  + C +++ C N   SYSC C PG+
Sbjct: 1788 EQGCSLPDPCDS--NPCPANSYCSNDWDSYSCSCDPGY 1823



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 19/76 (25%)

Query: 79   CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 138
            C   S C N   SY C C PGY        + +   N C D++ C   +HQ    +VC  
Sbjct: 1802 CPANSYCSNDWDSYSCSCDPGY--------YGDNCTNVC-DLNPC---EHQ----SVCTR 1845

Query: 139  TVGS---YSCRCRPGW 151
               +   Y+C C P +
Sbjct: 1846 KPSAPHGYTCECPPNY 1861


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score =  185 bits (469), Expect = 1e-46
 Identities = 179/612 (29%), Positives = 279/612 (45%), Gaps = 77/612 (12%)

Query: 164 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDYKPG-LANNTIQSILQALDEL 218
           TV      +T + PP     V++ ++S   ++V  + +    G L  N    ++  +  L
Sbjct: 327 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 386

Query: 219 LEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQV 278
           L +P D+          +A  LL  ++D+  GL  N SN  ++ + P+     + V    
Sbjct: 387 LHSPPDMLAP-------LAQRLLKVVDDI--GLQLNFSNTTISLTSPSLALAVIRVNASS 437

Query: 279 DRSVT-LRQNQAVMQLDWNQAQKSGDPGM----GKLLAEAP---LVLEPEKQMLLHETHQ 330
             + T + Q+ A +Q+           G       L+   P   + L    Q    ET  
Sbjct: 438 FNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFET-P 496

Query: 331 GLLQDGSP---ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVL---CVFWEHG 384
            L QD S     L+S VIS+ ++N   +NL+  VT T  H  + P Q  L   CVFW+ G
Sbjct: 497 ALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKH--INPSQDELTVRCVFWDLG 554

Query: 385 QNGC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPV------LTVITY 437
           +NG  G W+  GCS    R   TIC C+HL+SF VL+   D+     +      LT ITY
Sbjct: 555 RNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLL---DLSRTSVLPAQMMALTFITY 611

Query: 438 MGLSVSLLCLLLAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--L 494
           +G  +S + L +  +T++  + I+    S + +QL   L L +L+FL+      +K+  L
Sbjct: 612 IGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGL 671

Query: 495 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 554
           C  +A  LHY  L + TWM LEA +++L    L  V  + I +++ K    VG+GVPAV 
Sbjct: 672 CISVAVFLHYFLLVSFTWMGLEAFHMYLA---LVKVFNTYIRKYILKFCI-VGWGVPAVV 727

Query: 555 VAISAASRPHLYGTPSR-----------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTL 603
           V I     P  YG  S            CW+     F    +G  C IF +N+ +F+V L
Sbjct: 728 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 787

Query: 604 WILKNRLSSLNSEVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTII 662
            +   R+     ++   R T +   ++ A L F+LG TW       GP      YLF I 
Sbjct: 788 -VQLCRIKK-KKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIF 845

Query: 663 NSLQGVFIFLVYCLLSQQVREQYGK--------------WSK-GIRKLKTESEMHTLSSS 707
           N+LQG FIF+ YC+  + VR+Q+ +              WSK     LK ++    +SSS
Sbjct: 846 NTLQGFFIFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSS 905

Query: 708 AKADTSKPSTVN 719
           + +  S  ++ N
Sbjct: 906 SNSLQSSSNSTN 917


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score =  185 bits (469), Expect = 1e-46
 Identities = 179/612 (29%), Positives = 279/612 (45%), Gaps = 77/612 (12%)

Query: 164 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDYKPG-LANNTIQSILQALDEL 218
           TV      +T + PP     V++ ++S   ++V  + +    G L  N    ++  +  L
Sbjct: 335 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 394

Query: 219 LEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQV 278
           L +P D+          +A  LL  ++D+  GL  N SN  ++ + P+     + V    
Sbjct: 395 LHSPPDMLAP-------LAQRLLKVVDDI--GLQLNFSNTTISLTSPSLALAVIRVNASS 445

Query: 279 DRSVT-LRQNQAVMQLDWNQAQKSGDPGM----GKLLAEAP---LVLEPEKQMLLHETHQ 330
             + T + Q+ A +Q+           G       L+   P   + L    Q    ET  
Sbjct: 446 FNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFET-P 504

Query: 331 GLLQDGSP---ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVL---CVFWEHG 384
            L QD S     L+S VIS+ ++N   +NL+  VT T  H  + P Q  L   CVFW+ G
Sbjct: 505 ALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKH--INPSQDELTVRCVFWDLG 562

Query: 385 QNGC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPV------LTVITY 437
           +NG  G W+  GCS    R   TIC C+HL+SF VL+   D+     +      LT ITY
Sbjct: 563 RNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLL---DLSRTSVLPAQMMALTFITY 619

Query: 438 MGLSVSLLCLLLAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--L 494
           +G  +S + L +  +T++  + I+    S + +QL   L L +L+FL+      +K+  L
Sbjct: 620 IGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGL 679

Query: 495 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 554
           C  +A  LHY  L + TWM LEA +++L    L  V  + I +++ K    VG+GVPAV 
Sbjct: 680 CISVAVFLHYFLLVSFTWMGLEAFHMYLA---LVKVFNTYIRKYILKFCI-VGWGVPAVV 735

Query: 555 VAISAASRPHLYGTPSR-----------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTL 603
           V I     P  YG  S            CW+     F    +G  C IF +N+ +F+V L
Sbjct: 736 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 795

Query: 604 WILKNRLSSLNSEVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTII 662
            +   R+     ++   R T +   ++ A L F+LG TW       GP      YLF I 
Sbjct: 796 -VQLCRIKK-KKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIF 853

Query: 663 NSLQGVFIFLVYCLLSQQVREQYGK--------------WSK-GIRKLKTESEMHTLSSS 707
           N+LQG FIF+ YC+  + VR+Q+ +              WSK     LK ++    +SSS
Sbjct: 854 NTLQGFFIFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSS 913

Query: 708 AKADTSKPSTVN 719
           + +  S  ++ N
Sbjct: 914 SNSLQSSSNSTN 925


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score =  185 bits (469), Expect = 1e-46
 Identities = 179/612 (29%), Positives = 279/612 (45%), Gaps = 77/612 (12%)

Query: 164 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDYKPG-LANNTIQSILQALDEL 218
           TV      +T + PP     V++ ++S   ++V  + +    G L  N    ++  +  L
Sbjct: 349 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 408

Query: 219 LEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQV 278
           L +P D+          +A  LL  ++D+  GL  N SN  ++ + P+     + V    
Sbjct: 409 LHSPPDMLAP-------LAQRLLKVVDDI--GLQLNFSNTTISLTSPSLALAVIRVNASS 459

Query: 279 DRSVT-LRQNQAVMQLDWNQAQKSGDPGM----GKLLAEAP---LVLEPEKQMLLHETHQ 330
             + T + Q+ A +Q+           G       L+   P   + L    Q    ET  
Sbjct: 460 FNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFET-P 518

Query: 331 GLLQDGSP---ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVL---CVFWEHG 384
            L QD S     L+S VIS+ ++N   +NL+  VT T  H  + P Q  L   CVFW+ G
Sbjct: 519 ALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKH--INPSQDELTVRCVFWDLG 576

Query: 385 QNGC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPV------LTVITY 437
           +NG  G W+  GCS    R   TIC C+HL+SF VL+   D+     +      LT ITY
Sbjct: 577 RNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLL---DLSRTSVLPAQMMALTFITY 633

Query: 438 MGLSVSLLCLLLAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--L 494
           +G  +S + L +  +T++  + I+    S + +QL   L L +L+FL+      +K+  L
Sbjct: 634 IGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGL 693

Query: 495 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 554
           C  +A  LHY  L + TWM LEA +++L    L  V  + I +++ K    VG+GVPAV 
Sbjct: 694 CISVAVFLHYFLLVSFTWMGLEAFHMYLA---LVKVFNTYIRKYILKFCI-VGWGVPAVV 749

Query: 555 VAISAASRPHLYGTPSR-----------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTL 603
           V I     P  YG  S            CW+     F    +G  C IF +N+ +F+V L
Sbjct: 750 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 809

Query: 604 WILKNRLSSLNSEVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTII 662
            +   R+     ++   R T +   ++ A L F+LG TW       GP      YLF I 
Sbjct: 810 -VQLCRIKK-KKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIF 867

Query: 663 NSLQGVFIFLVYCLLSQQVREQYGK--------------WSK-GIRKLKTESEMHTLSSS 707
           N+LQG FIF+ YC+  + VR+Q+ +              WSK     LK ++    +SSS
Sbjct: 868 NTLQGFFIFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSS 927

Query: 708 AKADTSKPSTVN 719
           + +  S  ++ N
Sbjct: 928 SNSLQSSSNSTN 939


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score =  185 bits (469), Expect = 1e-46
 Identities = 179/612 (29%), Positives = 279/612 (45%), Gaps = 77/612 (12%)

Query: 164 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDYKPG-LANNTIQSILQALDEL 218
           TV      +T + PP     V++ ++S   ++V  + +    G L  N    ++  +  L
Sbjct: 346 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 405

Query: 219 LEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQV 278
           L +P D+          +A  LL  ++D+  GL  N SN  ++ + P+     + V    
Sbjct: 406 LHSPPDMLAP-------LAQRLLKVVDDI--GLQLNFSNTTISLTSPSLALAVIRVNASS 456

Query: 279 DRSVT-LRQNQAVMQLDWNQAQKSGDPGM----GKLLAEAP---LVLEPEKQMLLHETHQ 330
             + T + Q+ A +Q+           G       L+   P   + L    Q    ET  
Sbjct: 457 FNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFET-P 515

Query: 331 GLLQDGSP---ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVL---CVFWEHG 384
            L QD S     L+S VIS+ ++N   +NL+  VT T  H  + P Q  L   CVFW+ G
Sbjct: 516 ALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKH--INPSQDELTVRCVFWDLG 573

Query: 385 QNGC-GHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPV------LTVITY 437
           +NG  G W+  GCS    R   TIC C+HL+SF VL+   D+     +      LT ITY
Sbjct: 574 RNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLL---DLSRTSVLPAQMMALTFITY 630

Query: 438 MGLSVSLLCLLLAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--L 494
           +G  +S + L +  +T++  + I+    S + +QL   L L +L+FL+      +K+  L
Sbjct: 631 IGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGL 690

Query: 495 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 554
           C  +A  LHY  L + TWM LEA +++L    L  V  + I +++ K    VG+GVPAV 
Sbjct: 691 CISVAVFLHYFLLVSFTWMGLEAFHMYLA---LVKVFNTYIRKYILKFCI-VGWGVPAVV 746

Query: 555 VAISAASRPHLYGTPSR-----------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTL 603
           V I     P  YG  S            CW+     F    +G  C IF +N+ +F+V L
Sbjct: 747 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 806

Query: 604 WILKNRLSSLNSEVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTII 662
            +   R+     ++   R T +   ++ A L F+LG TW       GP      YLF I 
Sbjct: 807 -VQLCRIKK-KKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIF 864

Query: 663 NSLQGVFIFLVYCLLSQQVREQYGK--------------WSK-GIRKLKTESEMHTLSSS 707
           N+LQG FIF+ YC+  + VR+Q+ +              WSK     LK ++    +SSS
Sbjct: 865 NTLQGFFIFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSS 924

Query: 708 AKADTSKPSTVN 719
           + +  S  ++ N
Sbjct: 925 SNSLQSSSNSTN 936


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  177 bits (450), Expect = 2e-44
 Identities = 149/544 (27%), Positives = 248/544 (45%), Gaps = 54/544 (9%)

Query: 204 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 263
           A N  ++ L+A+ E+L  PG    +   +   V   L+D ++ V+  +S NL       +
Sbjct: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373

Query: 264 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSG-DPGMGKLLAEAPL 315
               + ++   V K + ++V           Q+ +Q+      +      +G L      
Sbjct: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAWSTVVGLLYHSMHY 433

Query: 316 VLE---PEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDT--QNLSSPVTFTFSHRSV 370
            L    P    +    H    QD      S +IS  +S   T  QNLS     T   +  
Sbjct: 434 YLNNIWPAHTKIAEAMHH---QDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHR 490

Query: 371 IPRQK------------VLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAV 418
           + R++            V C F +   +G G W+  GC+      T ++CRCTHL++FA+
Sbjct: 491 LTRKQHSEATNSSNRVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAI 549

Query: 419 LMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTSTSLHLQLS 472
           LM    ++        L+ I+Y+G S+S+LCL+   +TF +  +   I+N    +H  LS
Sbjct: 550 LMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLS 609

Query: 473 LCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 532
             + +A +L L++         C ++A  LHY +L+   WML+E L+L+       V+  
Sbjct: 610 FAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM-----VIKV 664

Query: 533 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIF 592
                   +  + +G+G P +   IS +     YGT + CWL    G IW F+ P   + 
Sbjct: 665 FGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVI 724

Query: 593 SVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGPA 651
            VN+ + +    ++ +++S+ N ++    +   L  KA A L  ILG +W  G+L V   
Sbjct: 725 VVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGC 783

Query: 652 ARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKAD 711
           A V  Y+F  +NSLQG+FIFL +CLL+ +VR  +        K KT+    T SSSA+  
Sbjct: 784 AVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT-SSSARTS 834

Query: 712 TSKP 715
            +KP
Sbjct: 835 NAKP 838


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score =  173 bits (438), Expect = 6e-43
 Identities = 122/365 (33%), Positives = 188/365 (51%), Gaps = 31/365 (8%)

Query: 340  LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQ-KVLCVFWE-HGQNGCGHWATTGC 396
            L + V+SA +S++   QNL+ PV  T  H        +V C FW+    NG G W ++GC
Sbjct: 2645 LTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWNSSGC 2704

Query: 397  STIGTRDTSTICRCTHLSSFAVLM----AHYDVQEEDPVLTVITYMGLSVSLLCLLLAAL 452
                T    TIC+C HL+ F VLM    +  D   E  +L +ITY G  +S + L +A +
Sbjct: 2705 KVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQ-ILALITYTGCGISSIFLGVAVV 2763

Query: 453  TFLLC-KAIQNTSTSLHLQLSLCLFLAHLLFLV-----AIDQTGHKVLCSIIAGTLHYLY 506
            T++   K  ++    + + L   L + +L+FL+     +  + G   +C   A  LHY  
Sbjct: 2764 TYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVG---VCITAAVALHYFL 2820

Query: 507  LATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLY 566
            L + TWM LEA++++L    + V N    N  +K  +  VG+G+PA+ VAI+ + +  LY
Sbjct: 2821 LVSFTWMGLEAVHMYLAL--VKVFNIYIPNYILKFCL--VGWGIPAIMVAITVSVKKDLY 2876

Query: 567  GTPSR----CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRN 622
            GT S     CW++ +  F    +   C IF +NL +F   L     +L+S+ S++   R 
Sbjct: 2877 GTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLV----QLNSVKSQIQKTRR 2932

Query: 623  TRMLA-FKATAQL-FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQ 680
              +L   K T  L F+LG TW       GP      YLF I N+LQG FIF+ +C++ + 
Sbjct: 2933 KMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKES 2992

Query: 681  VREQY 685
            VREQ+
Sbjct: 2993 VREQW 2997


>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
            sapiens]
          Length = 1221

 Score =  166 bits (420), Expect = 7e-41
 Identities = 142/476 (29%), Positives = 221/476 (46%), Gaps = 58/476 (12%)

Query: 287  NQAVMQLDWNQAQKSGDPGMGKLLAEAPLV-LEPEKQMLLHETH------QGLLQDGSP- 338
            N++  Q+D+   Q   DP    +L    L  L PE  +L+           GL QD  P 
Sbjct: 704  NESYFQMDFESGQV--DPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQ 761

Query: 339  --ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQN-GCGHWATTG 395
               L+S V++  + N   QNL  PV     H         +C FW+  +N   G W T+G
Sbjct: 762  RKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSG 821

Query: 396  CSTIGTRDTS-TICRCTHLSSFAVLM------AHYDVQEEDPVLTVITYMGLSVSLLCLL 448
            C      D S T+C C H + F VLM      +  D +    VLT I+Y+G  +S +   
Sbjct: 822  CVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTK-VLTFISYIGCGISAIFSA 880

Query: 449  LAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYL 505
               LT++  + ++    S + + LS  L   +LLFL+    T   V  LC  +A  LH+ 
Sbjct: 881  ATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFF 940

Query: 506  YLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPH- 564
             LAT TWM LEA+++++    L  V  + I R++ K    +G+G+PA+ V++  ASR + 
Sbjct: 941  LLATFTWMGLEAIHMYIA---LVKVFNTYIRRYILKFCI-IGWGLPALVVSVVLASRNNN 996

Query: 565  -LYGTPSR--------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNS 615
             +YG  S         CW+Q    F     G    +F +N+ +F+V +  +  R    ++
Sbjct: 997  EVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSN 1056

Query: 616  EVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVY 674
               TLR   +   ++   L F+LG TW       GP      YLF+I NSLQG+FIF+ +
Sbjct: 1057 R--TLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFH 1114

Query: 675  CLLSQQVREQYGK--------------WSK---GIRKLKTESEMHTLSSSAKADTS 713
            C + + V++Q+ +              WSK    I K  +++   +LSSS+    S
Sbjct: 1115 CAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNS 1170


>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
            sapiens]
          Length = 1250

 Score =  166 bits (420), Expect = 7e-41
 Identities = 142/476 (29%), Positives = 221/476 (46%), Gaps = 58/476 (12%)

Query: 287  NQAVMQLDWNQAQKSGDPGMGKLLAEAPLV-LEPEKQMLLHETH------QGLLQDGSP- 338
            N++  Q+D+   Q   DP    +L    L  L PE  +L+           GL QD  P 
Sbjct: 704  NESYFQMDFESGQV--DPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQ 761

Query: 339  --ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQN-GCGHWATTG 395
               L+S V++  + N   QNL  PV     H         +C FW+  +N   G W T+G
Sbjct: 762  RKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSG 821

Query: 396  CSTIGTRDTS-TICRCTHLSSFAVLM------AHYDVQEEDPVLTVITYMGLSVSLLCLL 448
            C      D S T+C C H + F VLM      +  D +    VLT I+Y+G  +S +   
Sbjct: 822  CVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTK-VLTFISYIGCGISAIFSA 880

Query: 449  LAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYL 505
               LT++  + ++    S + + LS  L   +LLFL+    T   V  LC  +A  LH+ 
Sbjct: 881  ATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFF 940

Query: 506  YLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPH- 564
             LAT TWM LEA+++++    L  V  + I R++ K    +G+G+PA+ V++  ASR + 
Sbjct: 941  LLATFTWMGLEAIHMYIA---LVKVFNTYIRRYILKFCI-IGWGLPALVVSVVLASRNNN 996

Query: 565  -LYGTPSR--------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNS 615
             +YG  S         CW+Q    F     G    +F +N+ +F+V +  +  R    ++
Sbjct: 997  EVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSN 1056

Query: 616  EVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVY 674
               TLR   +   ++   L F+LG TW       GP      YLF+I NSLQG+FIF+ +
Sbjct: 1057 R--TLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFH 1114

Query: 675  CLLSQQVREQYGK--------------WSK---GIRKLKTESEMHTLSSSAKADTS 713
            C + + V++Q+ +              WSK    I K  +++   +LSSS+    S
Sbjct: 1115 CAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNS 1170


>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
            sapiens]
          Length = 1193

 Score =  166 bits (420), Expect = 7e-41
 Identities = 142/476 (29%), Positives = 221/476 (46%), Gaps = 58/476 (12%)

Query: 287  NQAVMQLDWNQAQKSGDPGMGKLLAEAPLV-LEPEKQMLLHETH------QGLLQDGSP- 338
            N++  Q+D+   Q   DP    +L    L  L PE  +L+           GL QD  P 
Sbjct: 676  NESYFQMDFESGQV--DPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQ 733

Query: 339  --ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQN-GCGHWATTG 395
               L+S V++  + N   QNL  PV     H         +C FW+  +N   G W T+G
Sbjct: 734  RKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSG 793

Query: 396  CSTIGTRDTS-TICRCTHLSSFAVLM------AHYDVQEEDPVLTVITYMGLSVSLLCLL 448
            C      D S T+C C H + F VLM      +  D +    VLT I+Y+G  +S +   
Sbjct: 794  CVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTK-VLTFISYIGCGISAIFSA 852

Query: 449  LAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYL 505
               LT++  + ++    S + + LS  L   +LLFL+    T   V  LC  +A  LH+ 
Sbjct: 853  ATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFF 912

Query: 506  YLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPH- 564
             LAT TWM LEA+++++    L  V  + I R++ K    +G+G+PA+ V++  ASR + 
Sbjct: 913  LLATFTWMGLEAIHMYIA---LVKVFNTYIRRYILKFCI-IGWGLPALVVSVVLASRNNN 968

Query: 565  -LYGTPSR--------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNS 615
             +YG  S         CW+Q    F     G    +F +N+ +F+V +  +  R    ++
Sbjct: 969  EVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSN 1028

Query: 616  EVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVY 674
               TLR   +   ++   L F+LG TW       GP      YLF+I NSLQG+FIF+ +
Sbjct: 1029 R--TLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFH 1086

Query: 675  CLLSQQVREQYGK--------------WSK---GIRKLKTESEMHTLSSSAKADTS 713
            C + + V++Q+ +              WSK    I K  +++   +LSSS+    S
Sbjct: 1087 CAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNS 1142


>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
            sapiens]
          Length = 1222

 Score =  166 bits (420), Expect = 7e-41
 Identities = 142/476 (29%), Positives = 221/476 (46%), Gaps = 58/476 (12%)

Query: 287  NQAVMQLDWNQAQKSGDPGMGKLLAEAPLV-LEPEKQMLLHETH------QGLLQDGSP- 338
            N++  Q+D+   Q   DP    +L    L  L PE  +L+           GL QD  P 
Sbjct: 676  NESYFQMDFESGQV--DPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQ 733

Query: 339  --ILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQN-GCGHWATTG 395
               L+S V++  + N   QNL  PV     H         +C FW+  +N   G W T+G
Sbjct: 734  RKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSG 793

Query: 396  CSTIGTRDTS-TICRCTHLSSFAVLM------AHYDVQEEDPVLTVITYMGLSVSLLCLL 448
            C      D S T+C C H + F VLM      +  D +    VLT I+Y+G  +S +   
Sbjct: 794  CVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTK-VLTFISYIGCGISAIFSA 852

Query: 449  LAALTFLLCKAIQNTSTS-LHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYL 505
               LT++  + ++    S + + LS  L   +LLFL+    T   V  LC  +A  LH+ 
Sbjct: 853  ATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFF 912

Query: 506  YLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPH- 564
             LAT TWM LEA+++++    L  V  + I R++ K    +G+G+PA+ V++  ASR + 
Sbjct: 913  LLATFTWMGLEAIHMYIA---LVKVFNTYIRRYILKFCI-IGWGLPALVVSVVLASRNNN 968

Query: 565  -LYGTPSR--------CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNS 615
             +YG  S         CW+Q    F     G    +F +N+ +F+V +  +  R    ++
Sbjct: 969  EVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSN 1028

Query: 616  EVSTLRNTRMLAFKATAQL-FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVY 674
               TLR   +   ++   L F+LG TW       GP      YLF+I NSLQG+FIF+ +
Sbjct: 1029 R--TLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFH 1086

Query: 675  CLLSQQVREQYGK--------------WSK---GIRKLKTESEMHTLSSSAKADTS 713
            C + + V++Q+ +              WSK    I K  +++   +LSSS+    S
Sbjct: 1087 CAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNS 1142


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score =  155 bits (393), Expect = 9e-38
 Identities = 93/354 (26%), Positives = 171/354 (48%), Gaps = 18/354 (5%)

Query: 337  SPILLSDVISA--FLSNNDTQN-LSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGH--W 391
            +P++ S V+S   F   N  +  L SP++  F       R K +CV W+       H  W
Sbjct: 2436 NPVMNSPVVSVAVFHGRNFLRGILESPISLEFRLLQTANRSKAICVQWDPPGLAEQHGVW 2495

Query: 392  ATTGCSTIGTRDTSTICRCTHLSSFAVLM---AHYDVQEEDPVLTVITYMGLSVSLLCLL 448
                C  +    +   CRC+   +F VLM       ++ +  +L V T++ ++VS+  L+
Sbjct: 2496 TARDCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALV 2555

Query: 449  LAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLA 508
            L A   L  +++++    +H  ++  L +A LLFL+ I +T ++++C+ +A  LHY +L+
Sbjct: 2556 LTAAILLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHRTHNQLVCTAVAILLHYFFLS 2615

Query: 509  TLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGT 568
            T  W+ ++ L+L+        V   +++R   +    +G+GVPAV + ++    P  YG 
Sbjct: 2616 TFAWLFVQGLHLYRMQ-----VEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGN 2670

Query: 569  PSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAF 628
            P  CW+   +  IW F GPV  +  +N  +FL     L  R S    +    + + +   
Sbjct: 2671 PDFCWISVHEPLIWSFAGPVVLVIVMNGTMFL-----LAARTSCSTGQREAKKTSALTLR 2725

Query: 629  KATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVR 682
             +   L ++  +W  G+L V  +     YL   +  LQG+ + L++C+L+   R
Sbjct: 2726 SSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLAVLLLFCVLNADAR 2779



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 27/107 (25%), Positives = 36/107 (33%), Gaps = 23/107 (21%)

Query: 45   CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 104
            CRC PGF+   +   T ++ C             C     C   EG Y CVC P      
Sbjct: 1421 CRCPPGFTG--DFCETELDLC---------YSNPCRNGGACARREGGYTCVCRP------ 1463

Query: 105  GAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTV-GSYSCRCRPG 150
                F  E      +   C  G   C +   C +   G + C+C  G
Sbjct: 1464 ---RFTGEDCELDTEAGRCVPG--VCRNGGTCTDAPNGGFRCQCPAG 1505


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,491,207
Number of Sequences: 37866
Number of extensions: 1306035
Number of successful extensions: 5861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 3420
Number of HSP's gapped (non-prelim): 1089
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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