Search of human proteins with 23397653

Search of human proteins with 23397653

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397653 phosphatidylinositol glycan anchor biosynthesis,
class T precursor [Homo sapiens]
         (578 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397653 phosphatidylinositol glycan anchor biosynthesis, cla...  1192   0.0  
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]             33   0.55 
gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo...    33   0.94 
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    33   0.94 
gi|9256604 protocadherin beta 11 precursor [Homo sapiens]              33   0.94 
gi|9256606 protocadherin beta 12 precursor [Homo sapiens]              33   0.94 
gi|9910346 chromosome 15 open reading frame 24 [Homo sapiens]          32   1.6  
gi|31317307 proprotein convertase subtilisin/kexin type 9 prepro...    30   6.1  
gi|27903825 APG4 autophagy 4 homolog D [Homo sapiens]                  30   7.9  

>gi|23397653 phosphatidylinositol glycan anchor biosynthesis, class
           T precursor [Homo sapiens]
          Length = 578

 Score = 1192 bits (3083), Expect = 0.0
 Identities = 578/578 (100%), Positives = 578/578 (100%)

Query: 1   MAAAMPLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQR 60
           MAAAMPLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQR
Sbjct: 1   MAAAMPLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQR 60

Query: 61  EGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTV 120
           EGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTV
Sbjct: 61  EGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTV 120

Query: 121 TDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREV 180
           TDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREV
Sbjct: 121 TDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREV 180

Query: 181 VCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQ 240
           VCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQ
Sbjct: 181 VCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQ 240

Query: 241 TLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPP 300
           TLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPP
Sbjct: 241 TLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPP 300

Query: 301 TTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENEAPPVPFLHAQRYVSG 360
           TTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENEAPPVPFLHAQRYVSG
Sbjct: 301 TTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENEAPPVPFLHAQRYVSG 360

Query: 361 YGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQ 420
           YGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQ
Sbjct: 361 YGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQ 420

Query: 421 DRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVA 480
           DRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVA
Sbjct: 421 DRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVA 480

Query: 481 AKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCY 540
           AKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCY
Sbjct: 481 AKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCY 540

Query: 541 GSFYNLLTRTFHIEEPRTGGLAKRLANLIRRARGVPPL 578
           GSFYNLLTRTFHIEEPRTGGLAKRLANLIRRARGVPPL
Sbjct: 541 GSFYNLLTRTFHIEEPRTGGLAKRLANLIRRARGVPPL 578


>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
          Length = 4557

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 19/52 (36%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 475  VPSMVAAKPVDWEESPLFNSLFPVSDGSNYFV-RLYTEPLLVNLPTPDFSMP 525
            V ++V AKP+D E+  ++N    V+DG+N  V +++ + L  N   P+FS P
Sbjct: 1412 VGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQP 1463


>gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo
           sapiens]
          Length = 815

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 20/114 (17%)

Query: 433 QLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVA-AKPVDWEESPL 491
           QL A S T  ++  +  L  W     D + G     +V +  VP  V   KPV W     
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWG----DNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGY 199

Query: 492 FNSLFPVSDGSNYFVRLYTEP----------LLVNLPTPDF--SMPYNVICLTC 533
           ++S F  +DG  Y   ++ EP          LL N  TP     +P  VI + C
Sbjct: 200 YHSAFVTTDGELY---VFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVAC 250


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 20/114 (17%)

Query: 433 QLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVA-AKPVDWEESPL 491
           QL A S T  ++  +  L  W     D + G     +V +  VP  V   KPV W     
Sbjct: 144 QLSAGSNTSAALTEDGRLFMWG----DNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGY 199

Query: 492 FNSLFPVSDGSNYFVRLYTEP----------LLVNLPTPDF--SMPYNVICLTC 533
           ++S F  +DG  Y   ++ EP          LL N  TP     +P  VI + C
Sbjct: 200 YHSAFVTTDGELY---VFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVAC 250


>gi|9256604 protocadherin beta 11 precursor [Homo sapiens]
          Length = 797

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 8/83 (9%)

Query: 429 EMLIQLPANSVTKVSIQFERA------LLKWTEYTPDPNHGFYVSPSVL--SALVPSMVA 480
           +ML+++P NS        E A      +     YT  PN  F++   V+  +   P +V 
Sbjct: 137 QMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTISPNSHFHIKMRVIPDNRKYPELVL 196

Query: 481 AKPVDWEESPLFNSLFPVSDGSN 503
            K +D+EE P  + +    DG +
Sbjct: 197 DKALDYEELPELSFILSALDGGS 219


>gi|9256606 protocadherin beta 12 precursor [Homo sapiens]
          Length = 795

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 8/83 (9%)

Query: 429 EMLIQLPANSVTKVSIQFERA------LLKWTEYTPDPNHGFYVSPSVL--SALVPSMVA 480
           EML+++P NS        E A      +     YT +PN  F+V   V   +   P +V 
Sbjct: 137 EMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTINPNSHFHVKIRVNPDNRKYPELVL 196

Query: 481 AKPVDWEESPLFNSLFPVSDGSN 503
            K +D+EE P  + +    DG +
Sbjct: 197 DKALDYEERPELSFILTALDGGS 219


>gi|9910346 chromosome 15 open reading frame 24 [Homo sapiens]
          Length = 242

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 13/115 (11%)

Query: 402 ITSKGKENKPSYIHYQPAQDRLQ-PHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDP 460
           ITSKGK  +  Y++Y    + ++ P+ L+M    P +   K      R    WT++  +P
Sbjct: 112 ITSKGKM-RARYVNYIKTSEVVRLPYPLQMKSSGPPSYFIK------RESWGWTDFLMNP 164

Query: 461 NHGFYVSPSVLSALVPSMVAAKPVDW-----EESPLFNSLFPVSDGSNYFVRLYT 510
                V P ++  L+P +V     D      +   + NS   + D S +  RL++
Sbjct: 165 MVMMMVLPLLIFVLLPKVVNTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLFS 219


>gi|31317307 proprotein convertase subtilisin/kexin type 9
          preproprotein [Homo sapiens]
          Length = 692

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 17/32 (53%), Positives = 21/32 (65%), Gaps = 1/32 (3%)

Query: 5  MPLALLVLLLLGPGGWCLAEPPRDSLREELVI 36
          +PL LL+LLLLGP G   A+   D   EELV+
Sbjct: 13 LPLLLLLLLLLGPAG-ARAQEDEDGDYEELVL 43


>gi|27903825 APG4 autophagy 4 homolog D [Homo sapiens]
          Length = 474

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 7/63 (11%)

Query: 254 GKK--DW---SLFRMFSRTLTEPCPLASESRVYV--DITTYNQDNETLEVHPPPTTTYQD 306
           GKK  DW   SL     R   E C   +   VYV  D T Y  D   L   P PT  ++ 
Sbjct: 240 GKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKS 299

Query: 307 VIL 309
           V++
Sbjct: 300 VVI 302


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,846,289
Number of Sequences: 37866
Number of extensions: 1175363
Number of successful extensions: 2224
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2223
Number of HSP's gapped (non-prelim): 9
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.