Guide to the Human Genome
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Search of human proteins with 23110982

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
         (433 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23110982 potassium inwardly-rectifying channel, subfamily J, ...   875   0.0  
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis...   859   0.0  
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ...   833   0.0  
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ...   833   0.0  
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ...   833   0.0  
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]    624   e-179
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]    555   e-158
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]   555   e-158
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]   488   e-138
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi...   488   e-138
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [...   395   e-110
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]   389   e-108
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]    382   e-106
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]    372   e-103
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi...   341   9e-94
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]    332   3e-91
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [...   327   1e-89
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [...   327   1e-89
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H...   327   1e-89
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ...   327   1e-89
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [...   327   1e-89
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]   315   7e-86
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi...   315   7e-86
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi...   315   7e-86
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi...   285   4e-77
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi...   285   4e-77
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi...   285   4e-77
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ...   282   4e-76
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap...   189   3e-48
gi|52218846 olfactory receptor, family 10, subfamily T, member 2...    32   0.86 

>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
           member 12 [Homo sapiens]
          Length = 433

 Score =  875 bits (2260), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
           MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
Sbjct: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60

Query: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
           DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
Sbjct: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120

Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
           TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180

Query: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
           MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
Sbjct: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240

Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
           GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300

Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
           GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
Sbjct: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360

Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
           DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
Sbjct: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420

Query: 421 VLEQRPYRRESEI 433
           VLEQRPYRRESEI
Sbjct: 421 VLEQRPYRRESEI 433


>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
           susceptibility ion channel [Homo sapiens]
          Length = 433

 Score =  859 bits (2220), Expect = 0.0
 Identities = 426/433 (98%), Positives = 427/433 (98%)

Query: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
           MTAASRANPYSIVS EEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNI FANM
Sbjct: 1   MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM 60

Query: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
           DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG+IFWVIAVAHGDLEPAEG GR
Sbjct: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR 120

Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
           TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEEC VAVFMVVAQSIVGCIIDSFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI 180

Query: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
           MAKMARPKKRA TLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
Sbjct: 181 MAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240

Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
           GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300

Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
           GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
Sbjct: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360

Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
           DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
Sbjct: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420

Query: 421 VLEQRPYRRESEI 433
           VLEQRPYRR SEI
Sbjct: 421 VLEQRPYRRGSEI 433


>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
           negative regulator Kir2.2v isoform 1 [Homo sapiens]
          Length = 432

 Score =  833 bits (2151), Expect = 0.0
 Identities = 411/433 (94%), Positives = 421/433 (97%), Gaps = 1/433 (0%)

Query: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
           MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNIEFANM
Sbjct: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 60

Query: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
           DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFG+IFWVIAVAHGDLEPAEGRGR
Sbjct: 61  DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 120

Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
           TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEECPVAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 180

Query: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
           MAKM RPKKRAQTLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 181 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 240

Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
           GEYIPLDQIDIDVGFDKGLD  FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 300

Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
           G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 301 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 359

Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
           DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 360 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 419

Query: 421 VLEQRPYRRESEI 433
           VLEQRPYRRESEI
Sbjct: 420 VLEQRPYRRESEI 432


>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
           negative regulator Kir2.2v isoform 2 [Homo sapiens]
          Length = 534

 Score =  833 bits (2151), Expect = 0.0
 Identities = 411/433 (94%), Positives = 421/433 (97%), Gaps = 1/433 (0%)

Query: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
           MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNIEFANM
Sbjct: 103 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 162

Query: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
           DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFG+IFWVIAVAHGDLEPAEGRGR
Sbjct: 163 DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 222

Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
           TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEECPVAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 223 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 282

Query: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
           MAKM RPKKRAQTLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 283 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 342

Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
           GEYIPLDQIDIDVGFDKGLD  FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 343 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 402

Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
           G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 403 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 461

Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
           DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 462 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 521

Query: 421 VLEQRPYRRESEI 433
           VLEQRPYRRESEI
Sbjct: 522 VLEQRPYRRESEI 534


>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
           sapiens]
          Length = 432

 Score =  833 bits (2151), Expect = 0.0
 Identities = 411/433 (94%), Positives = 421/433 (97%), Gaps = 1/433 (0%)

Query: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM 60
           MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRC NRFVKKNGQCNIEFANM
Sbjct: 1   MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANM 60

Query: 61  DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR 120
           DEKSQRYLAD+FTTCVDIRWRYMLLIFSLAFLASWLLFG+IFWVIAVAHGDLEPAEGRGR
Sbjct: 61  DEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGR 120

Query: 121 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI 180
           TPCVMQVHGFMAAFLFSI+TQ TI YGLRCVTEECPVAVFMVVAQSIVGCII+SFMIGAI
Sbjct: 121 TPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAI 180

Query: 181 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE 240
           MAKM RPKKRAQTLLFSHNAVVALRDGKLC MWRVGNLRKSHIVEAHVRAQLIKPRVT+E
Sbjct: 181 MAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKE 240

Query: 241 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE 300
           GEYIPLDQIDIDVGFDKGLD  FLVSPITILHEIDEASPLFGISRQDL+ DDFEIV+ILE
Sbjct: 241 GEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILE 300

Query: 301 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK 360
           G+VEATAMTTQARSSYLANEILWGHRFEPVLF EKNQYKIDY HFHKTYEVPSTPRCSAK
Sbjct: 301 GIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAK 359

Query: 361 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG 420
           DLVENKFLLP ANSFCY+NELAFLSRDEEDEADGDQDGRSR+GL PQARHDFDRLQAGGG
Sbjct: 360 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG 419

Query: 421 VLEQRPYRRESEI 433
           VLEQRPYRRESEI
Sbjct: 420 VLEQRPYRRESEI 432


>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
          Length = 427

 Score =  624 bits (1610), Expect = e-179
 Identities = 305/431 (70%), Positives = 361/431 (83%), Gaps = 11/431 (2%)

Query: 6   RANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCRNRFVKKNGQCNIEFANMDEK 63
           R N YSIVSSEEDG+ L TM+ ANGFGNGK  VHTR++CR+RFVKK+G CN++F N+ EK
Sbjct: 5   RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64

Query: 64  SQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPA-EGRGRTP 122
            QRYLAD+FTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ + EG+    
Sbjct: 65  GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKA--- 121

Query: 123 CVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMA 182
           CV +V+ F AAFLFSIETQTTIGYG RCVT+ECP+AVFMVV QSIVGCIID+F+IGA+MA
Sbjct: 122 CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMA 181

Query: 183 KMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGE 242
           KMA+PKKR +TL+FSHNAV+A+RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K R+T EGE
Sbjct: 182 KMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGE 241

Query: 243 YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGM 302
           YIPLDQIDI+VGFD G+DRIFLVSPITI+HEIDE SPL+ +S+QD++  DFEIVVILEGM
Sbjct: 242 YIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGM 301

Query: 303 VEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDL 362
           VEATAMTTQ RSSYLANEILWGHR+EPVLFEEK+ YK+DYS FHKTYEVP+TP CSA+DL
Sbjct: 302 VEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDL 361

Query: 363 VENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVL 422
            E K++L +ANSFCYENE+A  S++E+D  +G  +  S D        D D        L
Sbjct: 362 AEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPL 416

Query: 423 EQRPYRRESEI 433
           E RP RRESEI
Sbjct: 417 EPRPLRRESEI 427


>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
          Length = 445

 Score =  555 bits (1429), Expect = e-158
 Identities = 284/440 (64%), Positives = 337/440 (76%), Gaps = 40/440 (9%)

Query: 33  NGKVHT-RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAF 91
           NG+ H  RR+ RNRFVKKNGQCN+ FAN+  KSQRY+AD+FTTCVD RWRYML+IFS AF
Sbjct: 7   NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66

Query: 92  LASWLLFGIIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 135
           L SWL FG++FW IA  HGDLE          PA G G        PC+M V+GF+ AFL
Sbjct: 67  LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126

Query: 136 FSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLL 195
           FS+ETQTTIGYG RCVTEECP+AV  VV QSIVGC+IDSFMIG IMAKMARPKKRAQTLL
Sbjct: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186

Query: 196 FSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGF 255
           FSH+AV+++RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246

Query: 256 DKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSS 315
           D GLDRIFLVSPI I+HEIDE SPL+G+ +++LE++DFEIVVILEGMVEATAMTTQARSS
Sbjct: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306

Query: 316 YLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL-----P 370
           YLA+EILWGHRFEPV+FEEK+ YK+DYS FHKTYEV  TP CSA++L E+K  +     P
Sbjct: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366

Query: 371 SANSFCYENELAFLSRDEED-----------------EADGDQDGRSRDGLSPQARHDFD 413
             ++FCYENELA +S++EE+                 EA   ++      L   +  D +
Sbjct: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426

Query: 414 RLQAGGGVLEQRPYRRESEI 433
           R+QA    L+   YRRES I
Sbjct: 427 RMQA-SLPLDNISYRRESAI 445


>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
          Length = 445

 Score =  555 bits (1429), Expect = e-158
 Identities = 284/440 (64%), Positives = 337/440 (76%), Gaps = 40/440 (9%)

Query: 33  NGKVHT-RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAF 91
           NG+ H  RR+ RNRFVKKNGQCN+ FAN+  KSQRY+AD+FTTCVD RWRYML+IFS AF
Sbjct: 7   NGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAF 66

Query: 92  LASWLLFGIIFWVIAVAHGDLE----------PAEGRGRT------PCVMQVHGFMAAFL 135
           L SWL FG++FW IA  HGDLE          PA G G        PC+M V+GF+ AFL
Sbjct: 67  LVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFL 126

Query: 136 FSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLL 195
           FS+ETQTTIGYG RCVTEECP+AV  VV QSIVGC+IDSFMIG IMAKMARPKKRAQTLL
Sbjct: 127 FSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLL 186

Query: 196 FSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGF 255
           FSH+AV+++RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKP +T+EGEY+PLDQ D++VG+
Sbjct: 187 FSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGY 246

Query: 256 DKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSS 315
           D GLDRIFLVSPI I+HEIDE SPL+G+ +++LE++DFEIVVILEGMVEATAMTTQARSS
Sbjct: 247 DIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSS 306

Query: 316 YLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL-----P 370
           YLA+EILWGHRFEPV+FEEK+ YK+DYS FHKTYEV  TP CSA++L E+K  +     P
Sbjct: 307 YLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPPP 366

Query: 371 SANSFCYENELAFLSRDEED-----------------EADGDQDGRSRDGLSPQARHDFD 413
             ++FCYENELA +S++EE+                 EA   ++      L   +  D +
Sbjct: 367 PPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLE 426

Query: 414 RLQAGGGVLEQRPYRRESEI 433
           R+QA    L+   YRRES I
Sbjct: 427 RMQA-SLPLDNISYRRESAI 445


>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
          Length = 436

 Score =  488 bits (1255), Expect = e-138
 Identities = 239/367 (65%), Positives = 286/367 (77%), Gaps = 11/367 (2%)

Query: 41  RCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGI 100
           R R RFVKK+G CN+ F N+  +  RYL+D+FTTCVD+RWR+M L+FS +FLASWLLFG+
Sbjct: 47  RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106

Query: 101 IFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVF 160
            FW+IA  HGDL  A      PC   V  F+AAFLF++ETQT+IGYG+R VTEECP AV 
Sbjct: 107 AFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164

Query: 161 MVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRK 220
            VV Q I GC++D+F++GA+MAKMA+PKKR +TL+FS NAVVALRD +LCLMWRVGNLR+
Sbjct: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224

Query: 221 SHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPL 280
           SH+VEAHVRAQL++PRVT EGEYIPLD  D+DVGFD G DRIFLVSPITI+HEID ASPL
Sbjct: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284

Query: 281 FGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKI 340
           + + R +L   DFE+VVILEGMVEATAMTTQ RSSYL  E+LWGHRFEPVLF+  +QY++
Sbjct: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344

Query: 341 DYSHFHKTYEVPSTPRCSAKDLVEN--------KFLLP-SANSFCYENELAFLSRDEEDE 391
           DY HFH+TYEVP TP CSAK+L E         K   P S  +FCYENELA     EEDE
Sbjct: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404

Query: 392 ADGDQDG 398
            D  ++G
Sbjct: 405 DDETEEG 411


>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
           sapiens]
          Length = 436

 Score =  488 bits (1255), Expect = e-138
 Identities = 239/367 (65%), Positives = 286/367 (77%), Gaps = 11/367 (2%)

Query: 41  RCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGI 100
           R R RFVKK+G CN+ F N+  +  RYL+D+FTTCVD+RWR+M L+FS +FLASWLLFG+
Sbjct: 47  RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106

Query: 101 IFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVF 160
            FW+IA  HGDL  A      PC   V  F+AAFLF++ETQT+IGYG+R VTEECP AV 
Sbjct: 107 AFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164

Query: 161 MVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRK 220
            VV Q I GC++D+F++GA+MAKMA+PKKR +TL+FS NAVVALRD +LCLMWRVGNLR+
Sbjct: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224

Query: 221 SHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPL 280
           SH+VEAHVRAQL++PRVT EGEYIPLD  D+DVGFD G DRIFLVSPITI+HEID ASPL
Sbjct: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284

Query: 281 FGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKI 340
           + + R +L   DFE+VVILEGMVEATAMTTQ RSSYL  E+LWGHRFEPVLF+  +QY++
Sbjct: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344

Query: 341 DYSHFHKTYEVPSTPRCSAKDLVEN--------KFLLP-SANSFCYENELAFLSRDEEDE 391
           DY HFH+TYEVP TP CSAK+L E         K   P S  +FCYENELA     EEDE
Sbjct: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404

Query: 392 ADGDQDG 398
            D  ++G
Sbjct: 405 DDETEEG 411


>gi|25121970 potassium inwardly-rectifying channel subfamily J9
           [Homo sapiens]
          Length = 393

 Score =  395 bits (1016), Expect = e-110
 Identities = 199/360 (55%), Positives = 266/360 (73%), Gaps = 7/360 (1%)

Query: 39  RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
           RRR R R+V+K+G+CN++  N+ E + RYL D+FTT VD++WR  LL F LA+  +WL F
Sbjct: 17  RRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75

Query: 99  GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158
           G I+W+IA   GDLE  E    TPCV  ++GF+AAFLFSIET+TTIGYG R +T++CP  
Sbjct: 76  GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135

Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218
           + +++ Q+I+G ++++FM+G +  K+++P KRA TL+FS +AVV+LRDG+LCLM+RVG+L
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195

Query: 219 RKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEAS 278
           R SHIVEA +RA+LI+ R T EGE+IPL Q D+ VGFD G DR+FLVSP+ I HEID AS
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255

Query: 279 PLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
           P +  SR+ LE DDFEIVVILEGMVEAT MT QARSSYL +E+LWGHRF  VL  E   Y
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315

Query: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDG 398
           ++DY+ FH+T+EVP TP CSA++L E    L +   +   + L     DE+ E +G  +G
Sbjct: 316 EVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL-----DEKVEEEGAGEG 369


>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
          Length = 419

 Score =  389 bits (999), Expect = e-108
 Identities = 194/373 (52%), Positives = 271/373 (72%), Gaps = 11/373 (2%)

Query: 40  RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
           ++ R R+++K+G+CN+   N+ E + RYL+D+FTT VD++WR+ LL+F++ +  +WL FG
Sbjct: 47  KKPRQRYMEKSGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105

Query: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159
            I+W+IA   GDL+    +   PCV  + GF++AFLFSIET+TTIGYG R +TE+CP  +
Sbjct: 106 FIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGI 165

Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219
            +++ Q+I+G I+++FM+G +  K+++PKKRA+TL+FS+NAV+++RD KLCLM+RVG+LR
Sbjct: 166 ILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLR 225

Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
            SHIVEA +RA+LIK R T+EGE+IPL+Q DI+VGFD G DR+FLVSP+ I HEI++ SP
Sbjct: 226 NSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSP 285

Query: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339
            + +S+  L  ++FE+VVILEGMVEAT MT QARSSY+  E+LWGHRF PVL  EK  Y+
Sbjct: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE 345

Query: 340 IDYSHFHKTYEVPSTPRCSAKDLVENK------FLLPSANSF--CYENEL-AFLSRDEED 390
           +DY+ FH TYE  +TP C AK+L E K        LPS      C E  L A   ++EED
Sbjct: 346 VDYNTFHDTYET-NTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEED 404

Query: 391 EADGDQDGRSRDG 403
           E  G    R   G
Sbjct: 405 EPKGLGGSREARG 417


>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
          Length = 423

 Score =  382 bits (980), Expect = e-106
 Identities = 191/368 (51%), Positives = 276/368 (75%), Gaps = 6/368 (1%)

Query: 38  TRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLL 97
           T+R+ + R+V+K+G+CN+   N+ E + RYL D+FTT VD++WR+ LLIF + +  +WL 
Sbjct: 49  TKRKIQ-RYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106

Query: 98  FGIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPV 157
           FG+I+W+IA   GD++  E    TPCV  ++GF++AFLFSIET+TTIGYG R +T++CP 
Sbjct: 107 FGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPE 166

Query: 158 AVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGN 217
            + +++ QS++G I+++FM+G +  K+++PKKRA+TL+FS +AV+++RDGKLCLM+RVG+
Sbjct: 167 GIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGD 226

Query: 218 LRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
           LR SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+  G DR+FLVSP+ I HEI++ 
Sbjct: 227 LRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQ 286

Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
           SP + IS+  L  ++ EIVVILEGMVEAT MT QARSSY+ +EILWG+RF PVL  E   
Sbjct: 287 SPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGF 346

Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDLVE--NKFLLPSANSFCYE-NELAFLSRDEEDEADG 394
           Y++DY+ FH+TYE  STP  SAK+L E  ++  LP + S   + N+ A L  +EE++   
Sbjct: 347 YEVDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLE 405

Query: 395 DQDGRSRD 402
           +Q  R+ D
Sbjct: 406 EQTERNGD 413


>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
          Length = 501

 Score =  372 bits (955), Expect = e-103
 Identities = 172/325 (52%), Positives = 241/325 (74%), Gaps = 1/325 (0%)

Query: 40  RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
           ++ R RFV KNG+CN++  N+  ++ RYL+D+FTT VD++WR+ L IF L +  +WL   
Sbjct: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99

Query: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159
            ++WVIA   GDL  A     TPCV  V+ F +AFLF IET+ TIGYG R +T++CP  +
Sbjct: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159

Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219
            + + QSI+G I+D+F+IG +  KM++PKKRA+TL+FS +AV+++RDGKL LM+RVGNLR
Sbjct: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219

Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
            SH+V A +R +L+K R T EGE++PLDQ+++DVGF  G D++FLVSP+TI H ID  SP
Sbjct: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279

Query: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339
            + +S++ ++T+ FEIVVILEG+VE T MT QAR+SY  +E+LWGHRF PV+  E+  +K
Sbjct: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339

Query: 340 IDYSHFHKTYEVPSTPRCSAKDLVE 364
           +DYS FH T+EVP TP  S K+  E
Sbjct: 340 VDYSQFHATFEVP-TPPYSVKEQEE 363


>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
           sapiens]
          Length = 390

 Score =  341 bits (874), Expect = 9e-94
 Identities = 171/331 (51%), Positives = 236/331 (71%), Gaps = 4/331 (1%)

Query: 40  RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
           R+ R RFV K G CN+   N+ E+  R+L D+FTT VD++W + LLIF+++FL SWLLF 
Sbjct: 29  RQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87

Query: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159
           + +W+IA AHGDL P+EG    PCV  +H F +AFLFSIE Q TIG+G R VTEECP+A+
Sbjct: 88  MAWWLIAFAHGDLAPSEGTAE-PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146

Query: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219
            +++ Q+IVG +I++ M+G I  K A+  +RA+TL+FS +AV+ALR G+LC M RVG+LR
Sbjct: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206

Query: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279
           KS I+ A +  Q+++   + EGE +PL Q+DI +    G + IFLV+P+ I H ID  SP
Sbjct: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266

Query: 280 LFGISRQDL-ETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQY 338
           L+ ++  DL    D EI+VILEG+VE T +TTQAR+SYLA+EILWG RF P++ EE  +Y
Sbjct: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326

Query: 339 KIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
            +DYS F  T +VP TP C+A+ L E+  LL
Sbjct: 327 SVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356


>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
          Length = 424

 Score =  332 bits (852), Expect = 3e-91
 Identities = 166/333 (49%), Positives = 233/333 (69%), Gaps = 10/333 (3%)

Query: 45  RFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWV 104
           RF+ K+G CN+   N+ E+  R+L D+FTT VD++WR+ L+IF+++FL SWLLF I++W+
Sbjct: 35  RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93

Query: 105 IAVAHGDLEP--------AEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECP 156
           +A AHGD+            G   T CV  V  F +AFLFSIE Q TIG+G R +TEECP
Sbjct: 94  VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153

Query: 157 VAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVG 216
           +A+ +++ Q+IVG II++ M+G I  K A+  +RA+TL+FS +AV+A+R+GKLC M+RVG
Sbjct: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213

Query: 217 NLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDE 276
           +LRKS I+ A VR Q++K   T EGE +P+ Q+DI V      + IFLV+P+ I H ID+
Sbjct: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273

Query: 277 ASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN 336
            SPL+ IS  DL   D E++VILEG+VE T +TTQAR+SY+A EI WGHRF  ++ EE+ 
Sbjct: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333

Query: 337 QYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
            Y +DYS F  T +V + PRCSA++L E   +L
Sbjct: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365


>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  327 bits (839), Expect = 1e-89
 Identities = 161/325 (49%), Positives = 232/325 (71%), Gaps = 6/325 (1%)

Query: 37  HTRRRCRNRFVKKNGQCNIEFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
           H+R+R R   V K+G+CNIEF N++ +S+  +  D++TT +D++WRY + IF  AFL SW
Sbjct: 16  HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73

Query: 96  LLFGIIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEE 154
             FG++++ +A  H DL E       TPCV  ++G  +AFLFS+ETQ TIGYG RCVTE+
Sbjct: 74  FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133

Query: 155 CPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWR 214
           C  A+F+++ QSI+G II+SFM GAI+AK++RPKKRA+T+ FS NAV++ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193

Query: 215 VGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEI 274
           V NLRKS ++ +H+  +L+K  VT EGE I LDQI+I+   D G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253

Query: 275 DEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEE 334
           D  SP F ++ + L   DFE+VV L+G VE+T+ T Q R+SY+  E+LWG+RF P++ + 
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313

Query: 335 K-NQYKIDYSHFHKTYEVPSTPRCS 358
           K  +Y++D+ +F KT EV  TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337


>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  327 bits (839), Expect = 1e-89
 Identities = 161/325 (49%), Positives = 232/325 (71%), Gaps = 6/325 (1%)

Query: 37  HTRRRCRNRFVKKNGQCNIEFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
           H+R+R R   V K+G+CNIEF N++ +S+  +  D++TT +D++WRY + IF  AFL SW
Sbjct: 16  HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73

Query: 96  LLFGIIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEE 154
             FG++++ +A  H DL E       TPCV  ++G  +AFLFS+ETQ TIGYG RCVTE+
Sbjct: 74  FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133

Query: 155 CPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWR 214
           C  A+F+++ QSI+G II+SFM GAI+AK++RPKKRA+T+ FS NAV++ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193

Query: 215 VGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEI 274
           V NLRKS ++ +H+  +L+K  VT EGE I LDQI+I+   D G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253

Query: 275 DEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEE 334
           D  SP F ++ + L   DFE+VV L+G VE+T+ T Q R+SY+  E+LWG+RF P++ + 
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313

Query: 335 K-NQYKIDYSHFHKTYEVPSTPRCS 358
           K  +Y++D+ +F KT EV  TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337


>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
           sapiens]
          Length = 391

 Score =  327 bits (839), Expect = 1e-89
 Identities = 161/325 (49%), Positives = 232/325 (71%), Gaps = 6/325 (1%)

Query: 37  HTRRRCRNRFVKKNGQCNIEFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
           H+R+R R   V K+G+CNIEF N++ +S+  +  D++TT +D++WRY + IF  AFL SW
Sbjct: 35  HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 92

Query: 96  LLFGIIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEE 154
             FG++++ +A  H DL E       TPCV  ++G  +AFLFS+ETQ TIGYG RCVTE+
Sbjct: 93  FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 152

Query: 155 CPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWR 214
           C  A+F+++ QSI+G II+SFM GAI+AK++RPKKRA+T+ FS NAV++ R GKLCL+ R
Sbjct: 153 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 212

Query: 215 VGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEI 274
           V NLRKS ++ +H+  +L+K  VT EGE I LDQI+I+   D G + +F +SP+TI H I
Sbjct: 213 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 272

Query: 275 DEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEE 334
           D  SP F ++ + L   DFE+VV L+G VE+T+ T Q R+SY+  E+LWG+RF P++ + 
Sbjct: 273 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 332

Query: 335 K-NQYKIDYSHFHKTYEVPSTPRCS 358
           K  +Y++D+ +F KT EV  TP C+
Sbjct: 333 KEGKYRVDFHNFSKTVEV-ETPHCA 356


>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  327 bits (839), Expect = 1e-89
 Identities = 161/325 (49%), Positives = 232/325 (71%), Gaps = 6/325 (1%)

Query: 37  HTRRRCRNRFVKKNGQCNIEFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
           H+R+R R   V K+G+CNIEF N++ +S+  +  D++TT +D++WRY + IF  AFL SW
Sbjct: 16  HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73

Query: 96  LLFGIIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEE 154
             FG++++ +A  H DL E       TPCV  ++G  +AFLFS+ETQ TIGYG RCVTE+
Sbjct: 74  FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133

Query: 155 CPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWR 214
           C  A+F+++ QSI+G II+SFM GAI+AK++RPKKRA+T+ FS NAV++ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193

Query: 215 VGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEI 274
           V NLRKS ++ +H+  +L+K  VT EGE I LDQI+I+   D G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253

Query: 275 DEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEE 334
           D  SP F ++ + L   DFE+VV L+G VE+T+ T Q R+SY+  E+LWG+RF P++ + 
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313

Query: 335 K-NQYKIDYSHFHKTYEVPSTPRCS 358
           K  +Y++D+ +F KT EV  TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337


>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  327 bits (839), Expect = 1e-89
 Identities = 161/325 (49%), Positives = 232/325 (71%), Gaps = 6/325 (1%)

Query: 37  HTRRRCRNRFVKKNGQCNIEFANMDEKSQR-YLADMFTTCVDIRWRYMLLIFSLAFLASW 95
           H+R+R R   V K+G+CNIEF N++ +S+  +  D++TT +D++WRY + IF  AFL SW
Sbjct: 16  HSRQRAR--LVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73

Query: 96  LLFGIIFWVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEE 154
             FG++++ +A  H DL E       TPCV  ++G  +AFLFS+ETQ TIGYG RCVTE+
Sbjct: 74  FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133

Query: 155 CPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWR 214
           C  A+F+++ QSI+G II+SFM GAI+AK++RPKKRA+T+ FS NAV++ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193

Query: 215 VGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEI 274
           V NLRKS ++ +H+  +L+K  VT EGE I LDQI+I+   D G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253

Query: 275 DEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEE 334
           D  SP F ++ + L   DFE+VV L+G VE+T+ T Q R+SY+  E+LWG+RF P++ + 
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313

Query: 335 K-NQYKIDYSHFHKTYEVPSTPRCS 358
           K  +Y++D+ +F KT EV  TP C+
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCA 337


>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
          Length = 418

 Score =  315 bits (806), Expect = 7e-86
 Identities = 163/325 (50%), Positives = 224/325 (68%), Gaps = 10/325 (3%)

Query: 39  RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
           +RR R R + K+G CN+ F ++  +   Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29  KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88

Query: 99  GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158
           G +FW+IA  HGDL        TPCV  VH F  AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 89  GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146

Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218
           V MV+ QSI+ CII++F+IGA +AKMA  +KRAQT+ FS+ A++ +RDGKLCLMWR+G+ 
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206

Query: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
           R +H+VE  VRAQL+  R TE+ E  + +   D+ +      D+I LV+P+TI+HEID  
Sbjct: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260

Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
           SPL+ + R+ +  D+FEI+V      ++T  + Q+RSSY+  EILWGHRF  VL  ++  
Sbjct: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320

Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
           YK++   F  + EV   P CSAK L
Sbjct: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344


>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
           sapiens]
          Length = 418

 Score =  315 bits (806), Expect = 7e-86
 Identities = 163/325 (50%), Positives = 224/325 (68%), Gaps = 10/325 (3%)

Query: 39  RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
           +RR R R + K+G CN+ F ++  +   Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29  KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88

Query: 99  GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158
           G +FW+IA  HGDL        TPCV  VH F  AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 89  GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146

Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218
           V MV+ QSI+ CII++F+IGA +AKMA  +KRAQT+ FS+ A++ +RDGKLCLMWR+G+ 
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206

Query: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
           R +H+VE  VRAQL+  R TE+ E  + +   D+ +      D+I LV+P+TI+HEID  
Sbjct: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260

Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
           SPL+ + R+ +  D+FEI+V      ++T  + Q+RSSY+  EILWGHRF  VL  ++  
Sbjct: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320

Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
           YK++   F  + EV   P CSAK L
Sbjct: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344


>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
           sapiens]
          Length = 418

 Score =  315 bits (806), Expect = 7e-86
 Identities = 163/325 (50%), Positives = 224/325 (68%), Gaps = 10/325 (3%)

Query: 39  RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
           +RR R R + K+G CN+ F ++  +   Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 29  KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88

Query: 99  GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158
           G +FW+IA  HGDL        TPCV  VH F  AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 89  GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146

Query: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218
           V MV+ QSI+ CII++F+IGA +AKMA  +KRAQT+ FS+ A++ +RDGKLCLMWR+G+ 
Sbjct: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206

Query: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
           R +H+VE  VRAQL+  R TE+ E  + +   D+ +      D+I LV+P+TI+HEID  
Sbjct: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260

Query: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
           SPL+ + R+ +  D+FEI+V      ++T  + Q+RSSY+  EILWGHRF  VL  ++  
Sbjct: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320

Query: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
           YK++   F  + EV   P CSAK L
Sbjct: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344


>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  285 bits (730), Expect = 4e-77
 Identities = 142/333 (42%), Positives = 216/333 (64%), Gaps = 11/333 (3%)

Query: 43  RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102
           R R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFG+I+
Sbjct: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85

Query: 103 WVIAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
           + IA  HGDLEP E     TPC+M+V     AFLFS+E+QTTIGYG+R +TEECP A+F+
Sbjct: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145

Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
           +VAQ ++  +I+ F+ G  +AK+ARPKKRA+T+ FSH AV+  ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205

Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
            +++  +  +L++  VT+EGE I L+Q  +    D   +  FL+ P+T  H +DE SPL 
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265

Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
            ++ Q+L+  +FE+VV+L   VE+T+   Q+R+SY+  EI WG  F PV+   KN +Y  
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325

Query: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
           D+S F    ++  +P C      S K  +E K+
Sbjct: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355


>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  285 bits (730), Expect = 4e-77
 Identities = 142/333 (42%), Positives = 216/333 (64%), Gaps = 11/333 (3%)

Query: 43  RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102
           R R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFG+I+
Sbjct: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85

Query: 103 WVIAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
           + IA  HGDLEP E     TPC+M+V     AFLFS+E+QTTIGYG+R +TEECP A+F+
Sbjct: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145

Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
           +VAQ ++  +I+ F+ G  +AK+ARPKKRA+T+ FSH AV+  ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205

Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
            +++  +  +L++  VT+EGE I L+Q  +    D   +  FL+ P+T  H +DE SPL 
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265

Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
            ++ Q+L+  +FE+VV+L   VE+T+   Q+R+SY+  EI WG  F PV+   KN +Y  
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325

Query: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
           D+S F    ++  +P C      S K  +E K+
Sbjct: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355


>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  285 bits (730), Expect = 4e-77
 Identities = 142/333 (42%), Positives = 216/333 (64%), Gaps = 11/333 (3%)

Query: 43  RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102
           R R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFG+I+
Sbjct: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85

Query: 103 WVIAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
           + IA  HGDLEP E     TPC+M+V     AFLFS+E+QTTIGYG+R +TEECP A+F+
Sbjct: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145

Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
           +VAQ ++  +I+ F+ G  +AK+ARPKKRA+T+ FSH AV+  ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205

Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
            +++  +  +L++  VT+EGE I L+Q  +    D   +  FL+ P+T  H +DE SPL 
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265

Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
            ++ Q+L+  +FE+VV+L   VE+T+   Q+R+SY+  EI WG  F PV+   KN +Y  
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325

Query: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
           D+S F    ++  +P C      S K  +E K+
Sbjct: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355


>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
           member 10 [Homo sapiens]
          Length = 379

 Score =  282 bits (722), Expect = 4e-76
 Identities = 141/313 (45%), Positives = 209/313 (66%), Gaps = 3/313 (0%)

Query: 43  RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102
           R R + K+G+ N+   ++ +K   YL D++TT +D++WRY LL+FS  F  +W LFG+++
Sbjct: 27  RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86

Query: 103 WVIAVAHGDL-EPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
           +++AVAHGDL E       TPCV+QVH    AFLFS+E+QTTIGYG R ++EECP+A+ +
Sbjct: 87  YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146

Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
           ++AQ ++  I++ F+ G  +AK+ARPKKRA+T+ FS +AVVA  +GK CLM RV N+RKS
Sbjct: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206

Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
            ++   V  +L++   T+EGE I L+Q+++    D   D  FL+ P+T  H +DE SPL 
Sbjct: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLK 266

Query: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVL-FEEKNQYKI 340
            +  +  E  DFE+V+IL G VE+T+ T Q R+SYL  EILWG+ F P +      +Y  
Sbjct: 267 DLPLRSGE-GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIA 325

Query: 341 DYSHFHKTYEVPS 353
           D+S F +  +V S
Sbjct: 326 DFSLFDQVVKVAS 338


>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
           sapiens]
          Length = 360

 Score =  189 bits (481), Expect = 3e-48
 Identities = 117/320 (36%), Positives = 178/320 (55%), Gaps = 13/320 (4%)

Query: 45  RFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWV 104
           R V K+G   ++     ++   YL D +   +D+RWR+M+L+FS +F+  WL+F ++++V
Sbjct: 19  RMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77

Query: 105 IAVAHGDLE---PAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
           +A  +GDLE    A     T CV  +  F AAF FS+ETQ TIGYG    + +CP A+ +
Sbjct: 78  LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137

Query: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
           +  Q ++G ++++F+ GA +AK+ARPK RA ++ F+  AVVA  DGK  L+++V N R S
Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197

Query: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFD--KGLDRIFLVSPITILHEIDEASP 279
            +    V A L + R  E G+   L Q  +D   D     +  F + P+T  H I  +SP
Sbjct: 198 PLTSVRVSAVLYQER--ENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252

Query: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-EKNQY 338
           L  + + +     FE+VV L  M E T    Q R+SYL +EI+  H F  +L    K +Y
Sbjct: 253 LATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311

Query: 339 KIDYSHFHKTYEVPSTPRCS 358
           +I   +F KT     TP  S
Sbjct: 312 QIKMENFDKTVPEFPTPLVS 331


>gi|52218846 olfactory receptor, family 10, subfamily T, member 2
           [Homo sapiens]
          Length = 314

 Score = 32.3 bits (72), Expect = 0.86
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 9/96 (9%)

Query: 10  YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM--------D 61
           Y+++ ++  GL L+++SGA GF    V T   C  RF   N + N  F +M         
Sbjct: 133 YTLIINKRLGLELISLSGATGFFIALVATNLICDMRFCGPN-RVNHYFCDMAPVIKLACT 191

Query: 62  EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLL 97
           +   + LA    + + I   ++L++ S  F+ + +L
Sbjct: 192 DTHVKELALFSLSILVIMVPFLLILISYGFIVNTIL 227


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,915,913
Number of Sequences: 37866
Number of extensions: 686255
Number of successful extensions: 1647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1566
Number of HSP's gapped (non-prelim): 33
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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