Search of human proteins with 23065563

Search of human proteins with 23065563

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
         (218 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]             450   e-127
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]   398   e-111
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]    377   e-105
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]    375   e-104
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]   343   5e-95
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi...   343   6e-95
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]             330   6e-91
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]   313   7e-86
gi|4504183 glutathione transferase [Homo sapiens]                      97   8e-21
gi|7657457 prostaglandin-D synthase [Homo sapiens]                     65   6e-11
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]           53   2e-07
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]          52   4e-07
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]           50   2e-06
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]           48   7e-06
gi|4504187 glutathione S-transferase theta 2 [Homo sapiens]            39   0.004
gi|124249394 glutathione S-transferase theta 2B [Homo sapiens]         39   0.004
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]            37   0.017
gi|113417526 PREDICTED: similar to glutathione S-transferase alp...    35   0.038
gi|169169045 PREDICTED: similar to glutathione S-transferase alp...    34   0.11 
gi|113418092 PREDICTED: similar to glutathione S-transferase alp...    34   0.11 
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             32   0.55 
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]          31   0.93 
gi|11125770 aminoacyl tRNA synthetase complex-interacting multif...    30   1.6  
gi|210147558 hypothetical protein LOC202051 [Homo sapiens]             29   2.7  
gi|21914927 helicase, lymphoid-specific [Homo sapiens]                 29   3.5  
gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b [Hom...    29   3.5  
gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a [Homo...    29   3.5  
gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]      28   7.9  
gi|56549111 optineurin [Homo sapiens]                                  28   7.9  
gi|56549109 optineurin [Homo sapiens]                                  28   7.9  

>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
          Length = 218

 Score =  450 bits (1158), Expect = e-127
 Identities = 218/218 (100%), Positives = 218/218 (100%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF
Sbjct: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN
Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180

Query: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218
           LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
Sbjct: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218


>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
          Length = 218

 Score =  398 bits (1022), Expect = e-111
 Identities = 191/218 (87%), Positives = 202/218 (92%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPM LGYWDIRGLAHAIRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDGAHKITQSNAIL YIARKHNLCGETEEEKIRVDILENQ MDNHM+L  +CY+P+F
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKPKYLEELPEKLKLYSEFLGKRPWFAG+KITFVDFL YDVLD+ RIFEPKCLDAF N
Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180

Query: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218
           LKDFISRFEGL+KISAYMKSS+FL   +F K A W +K
Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218


>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
          Length = 218

 Score =  377 bits (967), Expect = e-105
 Identities = 177/218 (81%), Positives = 198/218 (90%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPMTLGYW+IRGLAH+IRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDG HKITQSNAILRYIARKHNLCGE+E+E+IR DILENQ MD+ M+L +LCYDPDF
Sbjct: 61  PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKP+YL+ LPE LKLYS+FLGK+PWF GDKITFVDF+AYDVL+  ++FEP CLDAF N
Sbjct: 121 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN 180

Query: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218
           LKDFISRFEGL+KISAYMKSS+FL   +F K A W +K
Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK 218


>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
          Length = 218

 Score =  375 bits (964), Expect = e-104
 Identities = 181/218 (83%), Positives = 195/218 (89%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           M MTLGYWDIRGLAHAIRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDGAHKITQSNAIL YIARKHNLCGETEEEKIRVDILENQ MD   +L R+CY PDF
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKP+YLEELP  ++ +S+FLGKRPWF GDKITFVDFLAYDVLD+ RIFEP CLDAF N
Sbjct: 121 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN 180

Query: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218
           LKDFISRFEGL+KISAYMKSS+FL   L+ + A W +K
Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 218


>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
          Length = 195

 Score =  343 bits (881), Expect = 5e-95
 Identities = 164/189 (86%), Positives = 173/189 (91%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           M MTLGYWDIRGLAHAIRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDGAHKITQSNAIL YIARKHNLCGETEEEKIRVDILENQ MD   +L R+CY PDF
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKP+YLEELP  ++ +S+FLGKRPWF GDKITFVDFLAYDVLD+ RIFEP CLDAF N
Sbjct: 121 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN 180

Query: 181 LKDFISRFE 189
           LKDFISRFE
Sbjct: 181 LKDFISRFE 189


>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
           sapiens]
          Length = 191

 Score =  343 bits (880), Expect = 6e-95
 Identities = 159/189 (84%), Positives = 176/189 (93%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPMTLGYW+IRGLAH+IRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDG HKITQSNAILRYIARKHNLCGE+E+E+IR DILENQ MD+ M+L +LCYDPDF
Sbjct: 61  PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKP+YL+ LPE LKLYS+FLGK+PWF GDKITFVDF+AYDVL+  ++FEP CLDAF N
Sbjct: 121 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN 180

Query: 181 LKDFISRFE 189
           LKDFISRFE
Sbjct: 181 LKDFISRFE 189


>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
          Length = 225

 Score =  330 bits (846), Expect = 6e-91
 Identities = 156/216 (72%), Positives = 182/216 (84%)

Query: 3   MTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPY 62
           M LGYWDIRGLAHAIRLLLE+TD+SY EK+YT G+APDYDRSQWL+ KFKL LDFPNLPY
Sbjct: 7   MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66

Query: 63  LIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEK 122
           L+DG +KITQSNAILRYIARKHN+CGETEEEKIRVDI+ENQVMD   +L+RLCY  D EK
Sbjct: 67  LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126

Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLK 182
           LKP+YLEELP +LK +S FLGK  WFAG+K+TFVDFL YD+LD  RIF+PKCLD F NLK
Sbjct: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186

Query: 183 DFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218
            F+ RFE L+KI+AY++S QF +  +  K A W +K
Sbjct: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222


>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
          Length = 181

 Score =  313 bits (802), Expect = 7e-86
 Identities = 158/218 (72%), Positives = 168/218 (77%), Gaps = 37/218 (16%)

Query: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPM LGYWDIRGLAHAIRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120
           PYLIDGAHKITQSNAIL YIARKHNLCGETEEEKIRVDILENQ MDNHM+L  +CY+P+F
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180
           EKLKPKYLEELPEKLKLYSEFLGKRPWFAG+K                            
Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK---------------------------- 152

Query: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218
                    GL+KISAYMKSS+FL   +F K A W +K
Sbjct: 153 ---------GLEKISAYMKSSRFLPRPVFSKMAVWGNK 181


>gi|4504183 glutathione transferase [Homo sapiens]
          Length = 210

 Score = 97.4 bits (241), Expect = 8e-21
 Identities = 62/207 (29%), Positives = 104/207 (50%), Gaps = 13/207 (6%)

Query: 2   PMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLP 61
           P T+ Y+ +RG   A+R+LL     S+ E+  T+          W     K    +  LP
Sbjct: 3   PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54

Query: 62  YLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFE 121
              DG   + QSN ILR++ R   L G+ ++E   VD++ + V D   + + L Y  ++E
Sbjct: 55  KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113

Query: 122 KLKPKYLEELPEKLK----LYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDA 177
             K  Y++ LP +LK    L S+  G + +  GD+I+F D+   D+L +  +  P CLDA
Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173

Query: 178 FLNLKDFISRFEGLKKISAYMKSSQFL 204
           F  L  ++ R     K+ A++ S +++
Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYV 200


>gi|7657457 prostaglandin-D synthase [Homo sapiens]
          Length = 199

 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 54/203 (26%), Positives = 89/203 (43%), Gaps = 24/203 (11%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y+++RG A  IR +  Y D  Y + +    D P+           K  L F  +P L 
Sbjct: 6   LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55

Query: 65  DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEK-- 122
                + QS AI RY+ +  +L G TE E+  VD + +  +D+ M     C+ P  EK  
Sbjct: 56  VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-PWAEKKQ 109

Query: 123 -LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLD 176
            +K +   EL     P  ++    +LG R W  G+ +T+ DF          +F+P  LD
Sbjct: 110 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD 169

Query: 177 AFLNLKDFISRFEGLKKISAYMK 199
               L     + + +  ++ ++K
Sbjct: 170 NHPRLVTLRKKVQAIPAVANWIK 192


>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
          Length = 222

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 51/205 (24%), Positives = 91/205 (44%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y + RG   +IR LL        EK   L  A D D+ +  N+   L   F  +P + 
Sbjct: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59

Query: 65  DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+    ++D   M L+ L   P+    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
                 EK+K +Y     + LK +     ++ +  G+K+++ D    ++       +   
Sbjct: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174

Query: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
           + +F  LK   +R   L  +  +++
Sbjct: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199


>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
          Length = 222

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y +IRG   +IR LL      + EK   +  A D D+ +  N+ +   L F  +P + 
Sbjct: 7   LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59

Query: 65  DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
               K+ Q+ AIL YIA K+NL G+  +EK  +D+    + D   M L+     P+    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
                 EK K +Y     + LK + +      +  G+K++  D    ++L      +   
Sbjct: 120 KLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174

Query: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
           + +F  LK   +R   L  +  +++
Sbjct: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199


>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
          Length = 222

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y++ RG   + R LL      + EK   +  A D D+ +  N+ +   L F  +P + 
Sbjct: 7   LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59

Query: 65  DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+    + D   M L+     P+    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
                 EK+K +Y     + LK + +      +  G+K++  D    ++L      +   
Sbjct: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174

Query: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
           + +F  LK   +R   L  +  +++
Sbjct: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199


>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
          Length = 222

 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y++ RG    IR LL      + EK   +G A D  + +  N+     L F  +P + 
Sbjct: 7   LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59

Query: 65  DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+    + D N M L+     P+    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
                 EK K +Y     + L+ + +      +  G+K++  D    ++L      +   
Sbjct: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174

Query: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
           +  F  LK   +R   L  +  +++
Sbjct: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199


>gi|4504187 glutathione S-transferase theta 2 [Homo sapiens]
          Length = 244

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 28/173 (16%)

Query: 40  DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDI 99
           D  + Q  +++F        LP L DG   +T+S+AIL Y++ K+          ++   
Sbjct: 34  DLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARA 93

Query: 100 LENQVMDNHMELVRLCYDPDF--EKLKPKYLEELPEKLK-------------LYSEFLGK 144
             ++ +  H + +R  +      + L P    ++PE+               L  +FLG 
Sbjct: 94  RVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGD 153

Query: 145 RPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLKDFISRFEGLKKISAY 197
           RP+ AG ++T  D +A     ++ + +P  L   L        FEG  +++A+
Sbjct: 154 RPFLAGQQVTLADLMA-----LEELMQPVALGYEL--------FEGRPRLAAW 193


>gi|124249394 glutathione S-transferase theta 2B [Homo sapiens]
          Length = 244

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 28/173 (16%)

Query: 40  DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDI 99
           D  + Q  +++F        LP L DG   +T+S+AIL Y++ K+          ++   
Sbjct: 34  DLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARA 93

Query: 100 LENQVMDNHMELVRLCYDPDF--EKLKPKYLEELPEKLK-------------LYSEFLGK 144
             ++ +  H + +R  +      + L P    ++PE+               L  +FLG 
Sbjct: 94  RVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGD 153

Query: 145 RPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLKDFISRFEGLKKISAY 197
           RP+ AG ++T  D +A     ++ + +P  L   L        FEG  +++A+
Sbjct: 154 RPFLAGQQVTLADLMA-----LEELMQPVALGYEL--------FEGRPRLAAW 193


>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
          Length = 222

 Score = 36.6 bits (83), Expect = 0.017
 Identities = 33/154 (21%), Positives = 70/154 (45%), Gaps = 17/154 (11%)

Query: 57  FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCY 116
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+     ++  ++L+ L  
Sbjct: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDM----YVEGTLDLLELLI 107

Query: 117 DPDFEKLKP----KYLEELPEK-----LKLYSEFL--GKRPWFAGDKITFVDFLAYDVLD 165
              F  LKP    K +  + +K       ++ + L    + +  G++++  D +    + 
Sbjct: 108 MHPF--LKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTIL 165

Query: 166 MKRIFEPKCLDAFLNLKDFISRFEGLKKISAYMK 199
                 P  L AF  L+++  +   +  I  +++
Sbjct: 166 ALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLE 199


>gi|113417526 PREDICTED: similar to glutathione S-transferase
          alpha 3 [Homo sapiens]
          Length = 216

 Score = 35.4 bits (80), Expect = 0.038
 Identities = 16/38 (42%), Positives = 24/38 (63%)

Query: 57 FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEK 94
          F  +P +     K+ Q+ AIL YIA K+NLCG+  +E+
Sbjct: 30 FQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIKER 67


>gi|169169045 PREDICTED: similar to glutathione S-transferase
          alpha 3 [Homo sapiens]
          Length = 227

 Score = 33.9 bits (76), Expect = 0.11
 Identities = 15/38 (39%), Positives = 23/38 (60%)

Query: 57 FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEK 94
          F  +P +     K+ Q+ AIL YI  K+NLCG+  +E+
Sbjct: 41 FQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKER 78


>gi|113418092 PREDICTED: similar to glutathione S-transferase
          alpha 3 [Homo sapiens]
          Length = 216

 Score = 33.9 bits (76), Expect = 0.11
 Identities = 15/38 (39%), Positives = 23/38 (60%)

Query: 57 FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEK 94
          F  +P +     K+ Q+ AIL YI  K+NLCG+  +E+
Sbjct: 30 FQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKER 67


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 31.6 bits (70), Expect = 0.55
 Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 3/113 (2%)

Query: 25   DSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKH 84
            D S V   Y  GD  +    Q  N+  ++  D      LID    + + N +LR  +   
Sbjct: 1705 DVSAVRDNYCRGDIVEPGTKQ--NDDSRILTDIEE-GVLIDKGKWLLKENHLLRMSSENP 1761

Query: 85   NLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKL 137
             +CG  +   +   +  N     +     L   P  ++L    LEEL + L+L
Sbjct: 1762 GMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDELSSSELEELTQPLEL 1814


>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
          Length = 240

 Score = 30.8 bits (68), Expect = 0.93
 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 22/140 (15%)

Query: 40  DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNL----CGETEEEKI 95
           D  + Q L++ F        +P L DG   +T+S AIL Y+ RK+ +      +  + + 
Sbjct: 34  DLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARA 93

Query: 96  RVDILENQVMDNHMELVRLCYDPDFEKLK-PKYLEE--LPEKLK------------LYSE 140
           RVD     +   H  L R C    + K+  P +L E   P+ L             L  +
Sbjct: 94  RVD---EYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDK 150

Query: 141 FLGKRPWFAGDKITFVDFLA 160
           FL  + +  G  I+  D +A
Sbjct: 151 FLQNKAFLTGPHISLADLVA 170


>gi|11125770 aminoacyl tRNA synthetase complex-interacting
           multifunctional protein 2 [Homo sapiens]
          Length = 320

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 14/43 (32%), Positives = 23/43 (53%)

Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVL 164
           +LK    +E     +  +  LGK PW AG+++T  D + + VL
Sbjct: 243 QLKEGSSKEKAAVFRSMNSALGKSPWLAGNELTVADVVLWSVL 285


>gi|210147558 hypothetical protein LOC202051 [Homo sapiens]
          Length = 205

 Score = 29.3 bits (64), Expect = 2.7
 Identities = 14/50 (28%), Positives = 29/50 (58%)

Query: 91  EEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSE 140
           EEEK++  + E +V+   +E  +L ++     +K K L+E  +K +L ++
Sbjct: 77  EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITK 126


>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
          Length = 838

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 2/52 (3%)

Query: 91  EEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSEFL 142
           EEE++    LE +     +E  R+ +D +  +++ + L+ L EK  +YS+FL
Sbjct: 33  EEEQLEAAGLERE--RKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFL 82


>gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b [Homo
           sapiens]
          Length = 307

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 122 KLKPKYLEELPEK---LKLYSEFLGKRPWFAGDK 152
           K+   YLEE  +K   +  Y   +GKRPW  GD+
Sbjct: 81  KMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDE 114


>gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a [Homo
           sapiens]
          Length = 465

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 122 KLKPKYLEELPEK---LKLYSEFLGKRPWFAGDK 152
           K+   YLEE  +K   +  Y   +GKRPW  GD+
Sbjct: 81  KMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDE 114


>gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]
          Length = 653

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 14/47 (29%), Positives = 25/47 (53%)

Query: 99  ILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSEFLGKR 145
           IL  +VM+ +M + RL +DP + K   + +E L    ++   + G R
Sbjct: 543 ILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLR 589


>gi|56549111 optineurin [Homo sapiens]
          Length = 577

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 6/63 (9%)

Query: 89  ETEEEKIRVDILE---NQVMDNHMELVRLCYD---PDFEKLKPKYLEELPEKLKLYSEFL 142
           +TE+EK ++ +L+   N+++  H   ++   +    + EK+    L+EL EKL+L  + L
Sbjct: 378 KTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKAL 437

Query: 143 GKR 145
             +
Sbjct: 438 ASK 440


>gi|56549109 optineurin [Homo sapiens]
          Length = 577

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 6/63 (9%)

Query: 89  ETEEEKIRVDILE---NQVMDNHMELVRLCYD---PDFEKLKPKYLEELPEKLKLYSEFL 142
           +TE+EK ++ +L+   N+++  H   ++   +    + EK+    L+EL EKL+L  + L
Sbjct: 378 KTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKAL 437

Query: 143 GKR 145
             +
Sbjct: 438 ASK 440


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.141    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,036,110
Number of Sequences: 37866
Number of extensions: 346564
Number of successful extensions: 785
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 751
Number of HSP's gapped (non-prelim): 35
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.