Guide to the Human Genome
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Search of human proteins with 229892273

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
         (305 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]            647   0.0  
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]            430   e-121
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]             278   4e-75
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]             257   1e-68
gi|13569938 sialyltransferase 7E [Homo sapiens]                       225   4e-59
gi|21361444 sialytransferase 7F [Homo sapiens]                        219   2e-57
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    71   1e-12
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ...    71   1e-12
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H...    65   7e-11
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [...    64   2e-10
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H...    64   2e-10
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...    62   5e-10
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran...    61   1e-09
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i...    57   2e-08
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ...    57   2e-08
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]                54   2e-07
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H...    52   5e-07
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]               52   9e-07
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]               52   9e-07
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]               52   9e-07
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]               52   9e-07
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]               52   9e-07
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]               52   9e-07
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]                52   9e-07
gi|21264332 sialyltransferase 7A [Homo sapiens]                        49   7e-06
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]                47   3e-05
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...    46   4e-05
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...    46   4e-05
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    46   4e-05
gi|192448440 sialyltransferase 7B [Homo sapiens]                       45   1e-04

>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
          Length = 305

 Score =  647 bits (1668), Expect = 0.0
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MACILKRKSVIAVSFIAAFLFLLVVRLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRT 60
           MACILKRKSVIAVSFIAAFLFLLVVRLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRT
Sbjct: 1   MACILKRKSVIAVSFIAAFLFLLVVRLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRT 60

Query: 61  HYGYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVG 120
           HYGYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVG
Sbjct: 61  HYGYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVG 120

Query: 121 RMTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIY 180
           RMTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIY
Sbjct: 121 RMTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIY 180

Query: 181 PNAQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMIND 240
           PNAQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMIND
Sbjct: 181 PNAQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMIND 240

Query: 241 TYCKTEGYRKVPYHYYEQGRDECDEYFLHEHAPYGGHRFITEKKVFAKWAKKHRIIFTHP 300
           TYCKTEGYRKVPYHYYEQGRDECDEYFLHEHAPYGGHRFITEKKVFAKWAKKHRIIFTHP
Sbjct: 241 TYCKTEGYRKVPYHYYEQGRDECDEYFLHEHAPYGGHRFITEKKVFAKWAKKHRIIFTHP 300

Query: 301 NWTLS 305
           NWTLS
Sbjct: 301 NWTLS 305


>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
          Length = 210

 Score =  430 bits (1105), Expect = e-121
 Identities = 207/210 (98%), Positives = 208/210 (99%)

Query: 1   MACILKRKSVIAVSFIAAFLFLLVVRLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRT 60
           MACILKRKSVIAVSFIAAFLFLLVVRLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRT
Sbjct: 1   MACILKRKSVIAVSFIAAFLFLLVVRLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRT 60

Query: 61  HYGYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVG 120
           HYGYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVG
Sbjct: 61  HYGYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVG 120

Query: 121 RMTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIY 180
           RMTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIY
Sbjct: 121 RMTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIY 180

Query: 181 PNAQIYVTTEKRMSYCDGVFKKETGKDRVQ 210
           PNAQIYVTTEKRMSYCDGVFKKETGKD  +
Sbjct: 181 PNAQIYVTTEKRMSYCDGVFKKETGKDSTE 210


>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
          Length = 302

 Score =  278 bits (711), Expect = 4e-75
 Identities = 127/242 (52%), Positives = 175/242 (72%), Gaps = 2/242 (0%)

Query: 63  GYINVKTQEPLQLD-CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGR 121
           GY +V   +PL  + C  CA+VS+SGQM+G  +G EID + C++RMN APT G+E DVG+
Sbjct: 58  GYSSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQ 117

Query: 122 MTMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYP 181
            + +RVVSHTSVPLLL+N  ++F++A  T+Y++WG  R+M +   G  Y  L +   +YP
Sbjct: 118 RSTLRVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYP 177

Query: 182 NAQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDT 241
             Q+Y  TE+ M+YCD +F+ ETGK+R QSGS+LSTGWFT +LA++ C  I VYGM++D+
Sbjct: 178 GLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237

Query: 242 YCKTEGYRKVPYHYYEQGR-DECDEYFLHEHAPYGGHRFITEKKVFAKWAKKHRIIFTHP 300
           YC+ + +  VPYHY+E+GR DEC  Y  HE AP   HRFITEK VF++WAKK  I+F HP
Sbjct: 238 YCREKSHPSVPYHYFEKGRLDECQMYLAHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHP 297

Query: 301 NW 302
           +W
Sbjct: 298 SW 299


>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
          Length = 218

 Score =  257 bits (656), Expect = 1e-68
 Identities = 114/215 (53%), Positives = 157/215 (73%), Gaps = 1/215 (0%)

Query: 89  MVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKNPDYFFKEAN 148
           M+G  +G EID + C++RMN APT G+E DVG+ + +RVVSHTSVPLLL+N  ++F++A 
Sbjct: 1   MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60

Query: 149 TTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEKRMSYCDGVFKKETGKDR 208
            T+Y++WG  R+M +   G  Y  L +   +YP  Q+Y  TE+ M+YCD +F+ ETGK+R
Sbjct: 61  DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120

Query: 209 VQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKVPYHYYEQGR-DECDEYF 267
            QSGS+LSTGWFT +LA++ C  I VYGM++D+YC+ + +  VPYHY+E+GR DEC  Y 
Sbjct: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYL 180

Query: 268 LHEHAPYGGHRFITEKKVFAKWAKKHRIIFTHPNW 302
            HE AP   HRFITEK VF++WAKK  I+F HP+W
Sbjct: 181 AHEQAPRSAHRFITEKAVFSRWAKKRPIVFAHPSW 215


>gi|13569938 sialyltransferase 7E [Homo sapiens]
          Length = 336

 Score =  225 bits (573), Expect = 4e-59
 Identities = 104/242 (42%), Positives = 153/242 (63%), Gaps = 2/242 (0%)

Query: 63  GYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRM 122
           GY+ V   +PL++ C  CA+V++SG ++  + G++ID++ C+ RMN+APT+GY  DVG  
Sbjct: 79  GYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNR 138

Query: 123 TMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPN 182
           T +RV++H+S+  +L+N       +  T+++ WGP   MR+DG G VYN L     + P 
Sbjct: 139 TSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPR 198

Query: 183 AQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTY 242
            + ++ T  +M   D +FK+ETGKDR  S ++LSTGWFT  +A++ C  I+VYGM+   +
Sbjct: 199 LKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDF 258

Query: 243 CKTEGYRKVPYHYYEQ-GRDECDEYFLHEHAPYGG-HRFITEKKVFAKWAKKHRIIFTHP 300
           C+   +  VPYHYYE  G DEC  Y  HE    G  HRFITEK+VF  WA+   I F  P
Sbjct: 259 CRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFFQP 318

Query: 301 NW 302
           +W
Sbjct: 319 DW 320


>gi|21361444 sialytransferase 7F [Homo sapiens]
          Length = 333

 Score =  219 bits (558), Expect = 2e-57
 Identities = 106/244 (43%), Positives = 156/244 (63%), Gaps = 4/244 (1%)

Query: 63  GYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRM 122
           GY+ +   + L   C  C IVS+S  ++G K+G EI+R+ C  RMN+APT GY  DVG  
Sbjct: 91  GYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNK 150

Query: 123 TMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPN 182
           T  RVV+H+SV  +L+ P  F      T+++ WGP   M+K   G +  ++++   ++PN
Sbjct: 151 TTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQKP-QGSLVRVIQRAGLVFPN 209

Query: 183 AQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTY 242
            + Y  +  RM   D +F+ ETGKDR +S S+LSTGWFT ++A++ C  +HVYGM+   Y
Sbjct: 210 MEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNY 269

Query: 243 C-KTEGYRKVPYHYYE-QGRDECDEYFLHEHAPYGG-HRFITEKKVFAKWAKKHRIIFTH 299
           C +    +++PYHYYE +G DEC  Y  +EH+  G  HRFITEK+VF+ WA+ + I F+H
Sbjct: 270 CSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSH 329

Query: 300 PNWT 303
           P+WT
Sbjct: 330 PSWT 333


>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 15/168 (8%)

Query: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
           CA+V ++G ++   +G EID    + R N+APT+GYE+DVG  T IR+++      +L N
Sbjct: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351

Query: 140 PDYFFKEAN---TTIYVIWGP---FRNMRKDGNGIVYNMLKKTV---GIYPNAQIYVTTE 190
           P + F +++     I V W P     N+        YN+    +      PN   Y+   
Sbjct: 352 PSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHP 411

Query: 191 KRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMI 238
           K +     + ++ T K+++Q     S+G+   L+ M  C  +HVY  I
Sbjct: 412 KFIWQLWDIIQENT-KEKIQPNP-PSSGFIGILIMMSMCREVHVYEYI 457


>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 15/168 (8%)

Query: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
           CA+V ++G ++   +G EID    + R N+APT+GYE+DVG  T IR+++      +L N
Sbjct: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351

Query: 140 PDYFFKEAN---TTIYVIWGP---FRNMRKDGNGIVYNMLKKTV---GIYPNAQIYVTTE 190
           P + F +++     I V W P     N+        YN+    +      PN   Y+   
Sbjct: 352 PSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHP 411

Query: 191 KRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMI 238
           K +     + ++ T K+++Q     S+G+   L+ M  C  +HVY  I
Sbjct: 412 KFIWQLWDIIQENT-KEKIQPNP-PSSGFIGILIMMSMCREVHVYEYI 457


>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
           sapiens]
          Length = 350

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/184 (28%), Positives = 77/184 (41%), Gaps = 17/184 (9%)

Query: 77  CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLL 136
           C  CA+V NSG + G   G ++D  + I RMN APT G+E+DVG     R   H   P  
Sbjct: 149 CRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGS----RTTHHFMYPES 204

Query: 137 LKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEKRMSYC 196
            KN       AN +  ++     ++    + +    ++ T      + + V  EK   Y 
Sbjct: 205 AKN-----LPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPV-KSFLRVDKEKVQIYN 258

Query: 197 DGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKVPYHYY 256
              FK    +     G Y STG      A+  C  ++VYG   D+       R   +HY+
Sbjct: 259 PAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADS-------RGNWHHYW 311

Query: 257 EQGR 260
           E  R
Sbjct: 312 ENNR 315


>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
           [Homo sapiens]
          Length = 340

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 16/174 (9%)

Query: 71  EPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSH 130
           E   + C  CA+V NSG +     G EID    + RMN APT G+E DVG  T   +V  
Sbjct: 133 EKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYP 192

Query: 131 TSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVG---IYPNAQIYV 187
            S           F+E    + +I  PF+ +  D   +V  +   T+    I   A+I V
Sbjct: 193 ES-----------FRELGDNVSMILVPFKTI--DLEWVVSAITTGTISHTYIPVPAKIRV 239

Query: 188 TTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDT 241
             +K + Y     K          G Y STG  + + +M  C  + +YG   D+
Sbjct: 240 KQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADS 293


>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
           sapiens]
          Length = 340

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 16/174 (9%)

Query: 71  EPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSH 130
           E   + C  CA+V NSG +     G EID    + RMN APT G+E DVG  T   +V  
Sbjct: 133 EKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYP 192

Query: 131 TSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVG---IYPNAQIYV 187
            S           F+E    + +I  PF+ +  D   +V  +   T+    I   A+I V
Sbjct: 193 ES-----------FRELGDNVSMILVPFKTI--DLEWVVSAITTGTISHTYIPVPAKIRV 239

Query: 188 TTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDT 241
             +K + Y     K          G Y STG  + + +M  C  + +YG   D+
Sbjct: 240 KQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADS 293


>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform b [Homo sapiens]
          Length = 466

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 7/81 (8%)

Query: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
           CA+V ++G ++   +G EID    + R N+APT+GYE+DVG  T IR+++      +L N
Sbjct: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351

Query: 140 PDYFFKEAN---TTIYVIWGP 157
           P + F +++     I V W P
Sbjct: 352 PSHHFIDSSLYKDVILVAWDP 372


>gi|110815855 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 3 [Homo sapiens]
          Length = 380

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 55/203 (27%), Positives = 84/203 (41%), Gaps = 43/203 (21%)

Query: 78  DLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLL 137
           ++CA+V NSG + G + G EID+S  ++R N APT+ ++ DVGR T +            
Sbjct: 160 NICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTF--------- 210

Query: 138 KNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVG--IYPNAQIYVTTEKRMSY 195
            NP    K  N  + +         +D N   +  LKK  G  ++  A  + T+      
Sbjct: 211 -NPSILEKYYNNLLTI---------QDRNNF-FLSLKKLDGAILWIPAFFFHTSATVTRT 259

Query: 196 CDGVFKKETGKDRVQ--------------------SGSYLSTGWFTFLLAMDACYGIHVY 235
               F +  G+ +VQ                    S   LSTG   + LA   C  IH+Y
Sbjct: 260 LVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLY 319

Query: 236 GMINDTYCKTEGYRKVPYHYYEQ 258
           G     +        +PYHYY++
Sbjct: 320 GFWPFGF-DPNTREDLPYHYYDK 341


>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 21/187 (11%)

Query: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
           CA+VS++G +   ++G EID    + R N APT  +++DVG  T IR+++      L+  
Sbjct: 184 CAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ----LVTT 239

Query: 140 PDYFFKEA--NTTIYVIWGP------FRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEK 191
              F K++  N  I ++W P           ++ +   +N  K    ++PN   Y+  + 
Sbjct: 240 EKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYI-LKP 298

Query: 192 RMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKV 251
           +M +      +E   + +Q     S+G    ++ M  C  + +Y  +          RK 
Sbjct: 299 QMPWELWDILQEISPEEIQPNP-PSSGMLGIIIMMTLCDQVDIYEFL-------PSKRKT 350

Query: 252 PYHYYEQ 258
              YY Q
Sbjct: 351 DVCYYYQ 357


>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 21/187 (11%)

Query: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
           CA+VS++G +   ++G EID    + R N APT  +++DVG  T IR+++      L+  
Sbjct: 184 CAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQ----LVTT 239

Query: 140 PDYFFKEA--NTTIYVIWGP------FRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEK 191
              F K++  N  I ++W P           ++ +   +N  K    ++PN   Y+  + 
Sbjct: 240 EKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYI-LKP 298

Query: 192 RMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKV 251
           +M +      +E   + +Q     S+G    ++ M  C  + +Y  +          RK 
Sbjct: 299 QMPWELWDILQEISPEEIQPNP-PSSGMLGIIIMMTLCDQVDIYEFL-------PSKRKT 350

Query: 252 PYHYYEQ 258
              YY Q
Sbjct: 351 DVCYYYQ 357


>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
          Length = 331

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/197 (27%), Positives = 78/197 (39%), Gaps = 31/197 (15%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVP 134
           + C  C +V N G +  + +G +ID    I RMNN P  G+EE+VGR T  R+    SV 
Sbjct: 113 IPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV- 171

Query: 135 LLLKNPDYFFKEANTTIYVIWGPFRNMR-----KDGNGIVYNMLKKTVG---IYPNAQIY 186
                 D    + NTT+ +      ++R       G+ I  N   K      IY   QI 
Sbjct: 172 ----FSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIR 227

Query: 187 V-------TTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMIN 239
           +       T    + +   VF K       Q   + +TG     LA   C+ +H+ G   
Sbjct: 228 ILDPFIIRTAAYELLHFPKVFPKN------QKPKHPTTGIIAITLAFYICHEVHLAG--- 278

Query: 240 DTYCKTEGYRKVPYHYY 256
             +       K P HYY
Sbjct: 279 --FKYNFSDLKSPLHYY 293


>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
           sapiens]
          Length = 329

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 26/197 (13%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSV- 133
           L C  C +V N  ++    +G+ I++   + R+NNAP  GYE DVG  T +R+    S  
Sbjct: 111 LRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAH 170

Query: 134 --PLLLKNPDYF-----FKEAN-TTIYVIWGPFRNMRK---DGNGIVYNMLKKTVGIYPN 182
             P +  NPD       FK  +   I  I    + +RK       +++++  K + I   
Sbjct: 171 FDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNP 230

Query: 183 AQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGM-INDT 241
             + +  +K +S      +K   K         +TG     LA+  C  +H+ G    D 
Sbjct: 231 FFMEIAADKLLSLPMQQPRKIKQKP--------TTGLLAITLALHLCDLVHIAGFGYPDA 282

Query: 242 YCKTEGYRKVPYHYYEQ 258
           Y K     K   HYYEQ
Sbjct: 283 YNK-----KQTIHYYEQ 294


>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
          Length = 413

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 193 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 245


>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
          Length = 359

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 139 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 191


>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
          Length = 429

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 209 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 261


>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
          Length = 277

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 155 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 207


>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
          Length = 390

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 170 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 222


>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
          Length = 444

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 224 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 276


>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
          Length = 375

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 22/53 (41%), Positives = 33/53 (62%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRV 127
           L C  C IV N G +  + +G+ ID    + R+N+AP KG+E+DVG  T +R+
Sbjct: 155 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRI 207


>gi|21264332 sialyltransferase 7A [Homo sapiens]
          Length = 600

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 53/218 (24%), Positives = 83/218 (38%), Gaps = 31/218 (14%)

Query: 75  LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTM---IRVVSHT 131
           L C  CA+V N G +    +G EID    ++R++ A  KGYE+DVG  T        S T
Sbjct: 360 LRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLT 419

Query: 132 SVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTV-------------- 177
              L+L N    FK       V +  F    +D   +   ++ +TV              
Sbjct: 420 QSLLILGNRG--FKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQE 477

Query: 178 ----GIYPNAQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYL-STGWFTFLLAMDACYGI 232
                ++ +  + +  +  + Y    F +    D      Y  +TG    L A+  C  +
Sbjct: 478 AFREALHMDRYLLLHPD-FLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQV 536

Query: 233 HVYGMINDTYCKTEGYRKVPYHYYEQGRDECDEYFLHE 270
             YG I      TEG+ +   HYY+        Y  H+
Sbjct: 537 SAYGFI------TEGHERFSDHYYDTSWKRLIFYINHD 568


>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
          Length = 356

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 45/196 (22%), Positives = 78/196 (39%), Gaps = 22/196 (11%)

Query: 72  PLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAP-TKGYEEDVGRMTMIRVVSH 130
           P QL    CA+V N G +     G +ID ++ + R N  P +  Y +DVG  +       
Sbjct: 130 PFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQ------ 183

Query: 131 TSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVY-NMLKKTVGIYPNAQIYVT- 188
               L+  NP    +     ++       NM+   +  +Y        G  P+ ++Y T 
Sbjct: 184 ----LVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTL 239

Query: 189 ----TEKRMSYCDGVFKKETGKDRVQSGSY---LSTGWFTFLLAMDACYGIHVYGMINDT 241
                 + + + +  F +  GK     G +   LSTG F    A+  C  + +YG    +
Sbjct: 240 SDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFS 299

Query: 242 YCKTEGYRKVPYHYYE 257
               E  + + +HYY+
Sbjct: 300 VNMHE--QPISHHYYD 313


>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 2 [Homo sapiens]
          Length = 395

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 19/59 (32%), Positives = 34/59 (57%)

Query: 77  CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPL 135
           C  C ++ + G + G ++G+ +++   + R+N+AP +GY E VG  T IR+      PL
Sbjct: 169 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPL 227


>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 1 [Homo sapiens]
          Length = 418

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 19/59 (32%), Positives = 34/59 (57%)

Query: 77  CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPL 135
           C  C ++ + G + G ++G+ +++   + R+N+AP +GY E VG  T IR+      PL
Sbjct: 192 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPL 250


>gi|5031999 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
          Length = 359

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 53/199 (26%), Positives = 80/199 (40%), Gaps = 43/199 (21%)

Query: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
           CA+V NSG ++  + G EID  + + R N AP   +  DVG          T    +  N
Sbjct: 142 CAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVG----------TKSDFITMN 191

Query: 140 PDYFFKEANTTIYVIWGPFRNMRKDGNGIVY--NMLKKTVGIYPNAQIYVTTEKRMSYCD 197
           P        + +   +G FRN   D    V+  +ML  +V ++  A +    EK + + +
Sbjct: 192 P--------SVVQRAFGGFRN-ESDREKFVHRLSMLNDSV-LWIPAFMVKGGEKHVEWVN 241

Query: 198 GVFKKETGKDRVQ----------SGSYL---------STGWFTFLLAMDACYGIHVYGMI 238
            +  K   K R             G +L         STG   + LA   C  IH+YG  
Sbjct: 242 ALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFW 301

Query: 239 NDTYCKTEGYRKVPYHYYE 257
              + K    + V YHYY+
Sbjct: 302 --PFPKDLNGKAVKYHYYD 318


>gi|192448440 sialyltransferase 7B [Homo sapiens]
          Length = 374

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 20/47 (42%), Positives = 27/47 (57%)

Query: 77  CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMT 123
           C  CA+V N G + G + G  ID    ++R+N A  KG+E DVG  T
Sbjct: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKT 194


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,881,863
Number of Sequences: 37866
Number of extensions: 523058
Number of successful extensions: 1106
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1052
Number of HSP's gapped (non-prelim): 42
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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