Search of human proteins with 22749353

Search of human proteins with 22749353

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749353 phospholipase D5 [Homo sapiens]
         (444 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749353 phospholipase D5 [Homo sapiens]                           898   0.0  
gi|166197683 phospholipase D3 [Homo sapiens]                          277   1e-74
gi|72534684 phospholipase D3 [Homo sapiens]                           277   1e-74
gi|94681038 phospholipase D4 [Homo sapiens]                           254   8e-68
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       31   2.0  
gi|75832029 connexin 43-interacting protein 150 isoform a [Homo ...    31   2.6  
gi|20149640 dual oxidase 1 precursor [Homo sapiens]                    30   4.4  
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                    30   4.4  
gi|117553627 acetylserotonin O-methyltransferase-like [Homo sapi...    30   5.8  
gi|21483182 zinc finger with KRAB and SCAN domains 5 [Homo sapiens]    30   5.8  
gi|11036642 zinc finger with KRAB and SCAN domains 5 [Homo sapiens]    30   5.8  

>gi|22749353 phospholipase D5 [Homo sapiens]
          Length = 444

 Score =  898 bits (2320), Expect = 0.0
 Identities = 444/444 (100%), Positives = 444/444 (100%)

Query: 1   MRMDSQKKIAKINVGKRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSS 60
           MRMDSQKKIAKINVGKRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSS
Sbjct: 1   MRMDSQKKIAKINVGKRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSS 60

Query: 61  HWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMT 120
           HWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMT
Sbjct: 61  HWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMT 120

Query: 121 AYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSS 180
           AYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSS
Sbjct: 121 AYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSS 180

Query: 181 LKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSV 240
           LKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSV
Sbjct: 181 LKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSV 240

Query: 241 IDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLT 300
           IDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLT
Sbjct: 241 IDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLT 300

Query: 301 FNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIG 360
           FNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIG
Sbjct: 301 FNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIG 360

Query: 361 NFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSS 420
           NFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSS
Sbjct: 361 NFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSS 420

Query: 421 LFKLKPLSNKTATDDTGGKDPRNV 444
           LFKLKPLSNKTATDDTGGKDPRNV
Sbjct: 421 LFKLKPLSNKTATDDTGGKDPRNV 444


>gi|166197683 phospholipase D3 [Homo sapiens]
          Length = 490

 Score =  277 bits (709), Expect = 1e-74
 Identities = 154/400 (38%), Positives = 233/400 (58%), Gaps = 17/400 (4%)

Query: 20  LVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDL--NHTH---PSACQG 74
           LVE+IPEGL++   +  + S  Q W+ LL  A  S+DI S +W L  N TH   PSA QG
Sbjct: 85  LVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQG 144

Query: 75  QRLFEKLLQLTSQNIEIKLVSDVTADSKV---LEALKLKGAEVTYMNMTAYNKGRLQSSF 131
           + +  +L  L  + + +++     +  +    L+AL   GA+V  ++M     G L + F
Sbjct: 145 EEVLRQLQTLAPKGVNVRIAVSKPSGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKF 204

Query: 132 WIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSL-KFKSRVPQT 190
           W+VD+ H Y+GSA +DW+SL Q+KELGV+ YNCSCL  DL +IF  Y  L +  S +P T
Sbjct: 205 WVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPST 264

Query: 191 WSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYI 250
           W +     Y+ E  +++ LN T + A+++++P   CP  R+ D+ A+ +V+D+A+ ++Y+
Sbjct: 265 WPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYV 324

Query: 251 AVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAI 310
           AVM+YLP    S    +WP +D  +R A   R V+VRLL+S W  ++P    F+ SL A+
Sbjct: 325 AVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAAL 384

Query: 311 CTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFT 370
                +  ++VK F +  + A     Q    + R+N NKYMVT+ A YIG  +W GN FT
Sbjct: 385 RDNHTHSDIQVKLFVVPADEA-----QARIPYARVNHNKYMVTERATYIGTSNWSGNYFT 439

Query: 371 QNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTL 410
           + AGT L++ Q      RS   QL+ +F RDW SPY+  L
Sbjct: 440 ETAGTSLLVTQNGRGGLRS---QLEAIFLRDWDSPYSHDL 476


>gi|72534684 phospholipase D3 [Homo sapiens]
          Length = 490

 Score =  277 bits (709), Expect = 1e-74
 Identities = 154/400 (38%), Positives = 233/400 (58%), Gaps = 17/400 (4%)

Query: 20  LVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDL--NHTH---PSACQG 74
           LVE+IPEGL++   +  + S  Q W+ LL  A  S+DI S +W L  N TH   PSA QG
Sbjct: 85  LVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQG 144

Query: 75  QRLFEKLLQLTSQNIEIKLVSDVTADSKV---LEALKLKGAEVTYMNMTAYNKGRLQSSF 131
           + +  +L  L  + + +++     +  +    L+AL   GA+V  ++M     G L + F
Sbjct: 145 EEVLRQLQTLAPKGVNVRIAVSKPSGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKF 204

Query: 132 WIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSL-KFKSRVPQT 190
           W+VD+ H Y+GSA +DW+SL Q+KELGV+ YNCSCL  DL +IF  Y  L +  S +P T
Sbjct: 205 WVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPST 264

Query: 191 WSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYI 250
           W +     Y+ E  +++ LN T + A+++++P   CP  R+ D+ A+ +V+D+A+ ++Y+
Sbjct: 265 WPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYV 324

Query: 251 AVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAI 310
           AVM+YLP    S    +WP +D  +R A   R V+VRLL+S W  ++P    F+ SL A+
Sbjct: 325 AVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAAL 384

Query: 311 CTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFT 370
                +  ++VK F +  + A     Q    + R+N NKYMVT+ A YIG  +W GN FT
Sbjct: 385 RDNHTHSDIQVKLFVVPADEA-----QARIPYARVNHNKYMVTERATYIGTSNWSGNYFT 439

Query: 371 QNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTL 410
           + AGT L++ Q      RS   QL+ +F RDW SPY+  L
Sbjct: 440 ETAGTSLLVTQNGRGGLRS---QLEAIFLRDWDSPYSHDL 476


>gi|94681038 phospholipase D4 [Homo sapiens]
          Length = 506

 Score =  254 bits (650), Expect = 8e-68
 Identities = 144/402 (35%), Positives = 226/402 (56%), Gaps = 17/402 (4%)

Query: 17  RIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHW-----DLNHTHPSA 71
           ++ LVE+IP+ L  +  +P    L Q W+ LL+ A++SV + S +W     D+     S+
Sbjct: 95  QLVLVESIPQDLPSAAGSPSAQPLGQAWLQLLDTAQESVHVASYYWSLTGPDIGVNDSSS 154

Query: 72  CQGQRLFEKLLQLTSQNIEIKLVSD---VTADSKVLEALKLKGAEVTYMNMTAYNKGRLQ 128
             G+ L +KL QL  +NI + + +    +   S  L+ L  +GA V  + M    +G L 
Sbjct: 155 QLGEALLQKLQQLLGRNISLAVATSSPTLARTSTDLQVLAARGAHVRQVPMGRLTRGVLH 214

Query: 129 SSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKF-KSRV 187
           S FW+VD +H+Y+GSA +DW+SL Q+KELG + YNCS L  DL++ F  Y  L   K+ +
Sbjct: 215 SKFWVVDGRHIYMGSANMDWRSLTQVKELGAVIYNCSHLAQDLEKTFQTYWVLGVPKAVL 274

Query: 188 PQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQY 247
           P+TW +     ++  +      +   + A+ S SP   CP+ R+ D++A+ +V+  A+++
Sbjct: 275 PKTWPQNFSSHFNRFQPFHGLFDGVPTTAYFSASPPALCPQGRTRDLEALLAVMGSAQEF 334

Query: 248 VYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSL 307
           +Y +VM+Y P +  S    YWP LD  +R A   + VRVRLL+     TDP  F ++ SL
Sbjct: 335 IYASVMEYFPTTRFSHPPRYWPVLDNALRAAAFGKGVRVRLLVGCGLNTDPTMFPYLRSL 394

Query: 308 KAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGN 367
           +A+    AN S+ VK F +   N        N  F R+N +K+MVT+ AAYIG  +W  +
Sbjct: 395 QALSNPAANVSVDVKVFIVPVGN------HSNIPFSRVNHSKFMVTEKAAYIGTSNWSED 448

Query: 368 DFTQNAGTGLVINQADVRN--NRSIIKQLKDVFERDWYSPYA 407
            F+  AG GLV+ Q+        ++ +QL+ +FERDW S YA
Sbjct: 449 YFSSTAGVGLVVTQSPGAQPAGATVQEQLRQLFERDWSSRYA 490


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 10/98 (10%)

Query: 178 YSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQ--LNETKSQAFVSNSPKLFCPKNRSFDID 235
           Y S++  S + QTW+KR +G     K LQ    + E K    V  +     P+ +S D+ 
Sbjct: 46  YESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEET---VVPEEKSADVR 102

Query: 236 AIYSVIDDAKQYVYI-----AVMDYLPISSTSTKRTYW 268
                + ++ Q V I     +V   +  S  +++  YW
Sbjct: 103 EAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYW 140


>gi|75832029 connexin 43-interacting protein 150 isoform a [Homo
            sapiens]
          Length = 1344

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 30/147 (20%), Positives = 59/147 (40%), Gaps = 21/147 (14%)

Query: 14   VGKRIALVENIPEGLNYSENAPF-HLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSAC 72
            VG+++   ++    LN   +A   ++   Q W++ +      +D  SSH           
Sbjct: 1063 VGEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGP--------- 1113

Query: 73   QGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEA-----------LKLKGAEVTYMNMTA 121
            Q Q  F   L        I   +D+T  S +++            L L  +E+ +++M  
Sbjct: 1114 QMQDAFLSPLSNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMEL 1173

Query: 122  YNKGRLQSSFWIVDKQHVYIGSAGLDW 148
             +KG  +S   +    H+++ +  LDW
Sbjct: 1174 ASKGPHKSQVQLRYLLHIFMEAGCLDW 1200


>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 9/77 (11%)

Query: 24  IPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQ 83
           +P G+ Y  NA  H   FQG +N  +   +++ + +S+W  +  HPS    + +   LL 
Sbjct: 334 VPPGV-YMRNASCH---FQGVINRNSSVSRALRVCNSYW--SREHPSLQSAEDVDALLLG 387

Query: 84  LTSQNIEIK---LVSDV 97
           + SQ  E +   LV DV
Sbjct: 388 MASQIAEREDHVLVEDV 404


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 9/77 (11%)

Query: 24  IPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQ 83
           +P G+ Y  NA  H   FQG +N  +   +++ + +S+W  +  HPS    + +   LL 
Sbjct: 334 VPPGV-YMRNASCH---FQGVINRNSSVSRALRVCNSYW--SREHPSLQSAEDVDALLLG 387

Query: 84  LTSQNIEIK---LVSDV 97
           + SQ  E +   LV DV
Sbjct: 388 MASQIAEREDHVLVEDV 404


>gi|117553627 acetylserotonin O-methyltransferase-like [Homo
           sapiens]
          Length = 621

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)

Query: 348 NKYMVTDGAAYIGNFDWVGNDFTQNAGTGL--VINQADVRNNRSIIKQLKDVFERDWY 403
           N Y+ +DG   +  F    ND T N  T L   I +   +++R++ K+ +D+F+  +Y
Sbjct: 362 NVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYY 419


>gi|21483182 zinc finger with KRAB and SCAN domains 5 [Homo sapiens]
          Length = 839

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 18/77 (23%), Positives = 33/77 (42%)

Query: 367 NDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKP 426
           +D  +N G+   +      N   I+KQ+ D  E  W +P        + P+ + +  LK 
Sbjct: 245 DDRKENYGSITSMGYESRDNMELIVKQISDDSESHWVAPEHTERSVPQDPDFAEVSDLKG 304

Query: 427 LSNKTATDDTGGKDPRN 443
           +  +   + T GK  +N
Sbjct: 305 MVQRWQVNPTVGKSRQN 321


>gi|11036642 zinc finger with KRAB and SCAN domains 5 [Homo sapiens]
          Length = 839

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 18/77 (23%), Positives = 33/77 (42%)

Query: 367 NDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKP 426
           +D  +N G+   +      N   I+KQ+ D  E  W +P        + P+ + +  LK 
Sbjct: 245 DDRKENYGSITSMGYESRDNMELIVKQISDDSESHWVAPEHTERSVPQDPDFAEVSDLKG 304

Query: 427 LSNKTATDDTGGKDPRN 443
           +  +   + T GK  +N
Sbjct: 305 MVQRWQVNPTVGKSRQN 321


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,046,294
Number of Sequences: 37866
Number of extensions: 598190
Number of successful extensions: 1339
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1317
Number of HSP's gapped (non-prelim): 11
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.