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Search of human proteins with 225703077
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
(190 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 378 e-105
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 273 6e-74
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 186 1e-47
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 95 3e-20
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 88 4e-18
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 88 4e-18
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 86 1e-17
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 86 3e-17
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 85 3e-17
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 83 1e-16
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 83 2e-16
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 82 2e-16
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 80 8e-16
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 80 8e-16
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 80 8e-16
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 79 3e-15
gi|56237018 testis and skeletal muscle-specific dual specificity... 74 1e-13
gi|56117822 testis and skeletal muscle-specific dual specificity... 74 1e-13
gi|56117820 testis and skeletal muscle-specific dual specificity... 74 1e-13
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 73 1e-13
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 73 1e-13
gi|239582767 slingshot homolog 3 [Homo sapiens] 72 4e-13
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 71 5e-13
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 71 6e-13
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 68 5e-12
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 68 5e-12
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 68 5e-12
gi|37674210 slingshot 2 [Homo sapiens] 67 7e-12
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 67 1e-11
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 65 5e-11
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 378 bits (970), Expect = e-105
Identities = 190/190 (100%), Positives = 190/190 (100%)
Query: 1 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN 60
MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN
Sbjct: 1 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN 60
Query: 61 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY 120
VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
Sbjct: 61 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY 120
Query: 121 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY 180
LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY
Sbjct: 121 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY 180
Query: 181 EKDLRMMISM 190
EKDLRMMISM
Sbjct: 181 EKDLRMMISM 190
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 273 bits (698), Expect = 6e-74
Identities = 131/190 (68%), Positives = 163/190 (85%), Gaps = 2/190 (1%)
Query: 1 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN 60
MTA + +F +QPS+ SQIT+SL++SNGVAAN+KL+LSSN+IT ++N SVEVVN
Sbjct: 1 MTAPSCAFPVQ--FRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVN 58
Query: 61 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY 120
+E IQY++VPV D+ +SRL DFFDPIAD IH+++M+QGRTLLHC AGVSRSA+LCLAY
Sbjct: 59 TLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118
Query: 121 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY 180
LMKYH+MSLLDAHTWTKS RPIIRPN+GFWEQLI+YEF+LF NTV M++SPVG IPDIY
Sbjct: 119 LMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIY 178
Query: 181 EKDLRMMISM 190
EK++R+MI +
Sbjct: 179 EKEVRLMIPL 188
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 186 bits (472), Expect = 1e-47
Identities = 84/175 (48%), Positives = 126/175 (72%)
Query: 14 VQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPV 73
+ + I +QIT SLFL G A+++ LL + IT IVNA++E+ N + +Y+KVP+
Sbjct: 19 ISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPL 78
Query: 74 TDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAH 133
D + + +FD +AD IH++ + G TL+HC AGVSRSA+LC+AYLMK+H++ LL+A+
Sbjct: 79 ADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
Query: 134 TWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIYEKDLRMMI 188
W K+RRP+IRPN GFW QLI+YE +LF +TV+M+ +P G +PD+YEK+ R ++
Sbjct: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLM 193
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 95.1 bits (235), Expect = 3e-20
Identities = 54/155 (34%), Positives = 83/155 (53%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
+I L+L + A+ K +L + ITA++N S N F QY +PV D + +
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISS 235
Query: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
+F+ D I +I GR +HC AG+SRSA++CLAYLM+ + + L +A + K RR II
Sbjct: 236 WFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSII 295
Query: 144 RPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPD 178
PN F QL+ +E ++ + SP + D
Sbjct: 296 SPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLD 330
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 88.2 bits (217), Expect = 4e-18
Identities = 52/151 (34%), Positives = 80/151 (52%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
+I L+L + A + +L + ITA++N S + N F QY +PV D + +
Sbjct: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISS 257
Query: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
+F + I + +GR L+HC AG+SRSA++CLAYLM + L +A + K RR II
Sbjct: 258 WFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSII 317
Query: 144 RPNNGFWEQLINYEFKLFNNNTVRMINSPVG 174
PN F QL+ +E ++ + SP G
Sbjct: 318 SPNFSFMGQLLQFESQVLATSCAAEAASPSG 348
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 88.2 bits (217), Expect = 4e-18
Identities = 52/151 (34%), Positives = 80/151 (52%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
+I L+L + A + +L + ITA++N S + N F QY +PV D + +
Sbjct: 107 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISS 166
Query: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
+F + I + +GR L+HC AG+SRSA++CLAYLM + L +A + K RR II
Sbjct: 167 WFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSII 226
Query: 144 RPNNGFWEQLINYEFKLFNNNTVRMINSPVG 174
PN F QL+ +E ++ + SP G
Sbjct: 227 SPNFSFMGQLLQFESQVLATSCAAEAASPSG 257
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 86.3 bits (212), Expect = 1e-17
Identities = 49/143 (34%), Positives = 75/143 (52%), Gaps = 2/143 (1%)
Query: 29 LFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEG--IQYIKVPVTDARDSRLYDFFD 86
LFL N A D + I ++N + + +E Y ++P TD+ L +F+
Sbjct: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
Query: 87 PIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPN 146
+ I L+HC AGVSRSA++ +AYLMK+ M++ DA+ + K +RPII PN
Sbjct: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
Query: 147 NGFWEQLINYEFKLFNNNTVRMI 169
F QL+ +E L N T R++
Sbjct: 449 LNFMGQLLEFEEDLNNGVTPRIL 471
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 85.5 bits (210), Expect = 3e-17
Identities = 45/137 (32%), Positives = 73/137 (53%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
+I L+L + A+ L++ ITA++N S + Y +PV D+ + +
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS 240
Query: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
F D I + + G+ L+HC AG+SRS ++C+AYLMK L +A + K RR ++
Sbjct: 241 HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV 300
Query: 144 RPNNGFWEQLINYEFKL 160
PN GF QL+ YE ++
Sbjct: 301 SPNFGFMGQLLQYESEI 317
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 85.1 bits (209), Expect = 3e-17
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-FFEGIQYIKVPVTDARDSRL 81
++I +L+L +K L+ N I ++NAS F +++VPV D+ ++
Sbjct: 160 TRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKI 219
Query: 82 YDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRP 141
+ D D I G L+HC+AG+SRSA++ +AY+MK MSL +A+ + K +RP
Sbjct: 220 LPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP 279
Query: 142 IIRPNNGFWEQLINYEFKLFN 162
I PN F QL++YE K+ N
Sbjct: 280 TISPNFNFLGQLLDYEKKIKN 300
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 83.2 bits (204), Expect = 1e-16
Identities = 43/129 (33%), Positives = 67/129 (51%)
Query: 29 LFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPI 88
L L + AA+D L N++T I+N + V N F Y + + D ++ + +F
Sbjct: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
Query: 89 ADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNG 148
+ I + G L+HC AGVSR+A++ + +LM S A + K+ RP I PN+G
Sbjct: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
Query: 149 FWEQLINYE 157
F EQL Y+
Sbjct: 193 FMEQLRTYQ 201
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 82.8 bits (203), Expect = 2e-16
Identities = 48/134 (35%), Positives = 72/134 (53%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
+I LFL + ++D L + ITA++N S N F +Y +PV D + +
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISA 234
Query: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
+F I + GR L+HC AG+SRSA++CLAYLM+ + L +A + K RR +I
Sbjct: 235 WFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVI 294
Query: 144 RPNNGFWEQLINYE 157
PN F QL+ +E
Sbjct: 295 SPNFSFMGQLLQFE 308
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 82.4 bits (202), Expect = 2e-16
Identities = 49/146 (33%), Positives = 70/146 (47%)
Query: 12 QGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKV 71
+G P ++ SLFL + AA + L+ +T VN S + G+ ++V
Sbjct: 9 RGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRV 68
Query: 72 PVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLD 131
PV D L +P + G L++C G SRSA++C AYLM++ +SL
Sbjct: 69 PVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAK 128
Query: 132 AHTWTKSRRPIIRPNNGFWEQLINYE 157
A KS RP+ PN GFW QL YE
Sbjct: 129 AFQMVKSARPVAEPNPGFWSQLQKYE 154
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 80.5 bits (197), Expect = 8e-16
Identities = 48/145 (33%), Positives = 80/145 (55%), Gaps = 2/145 (1%)
Query: 17 PSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-FFEGIQYIKVPVTD 75
PS+ ++I L+L + +K L++ N I+ ++NAS F ++++VP+ D
Sbjct: 157 PSV-GLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPIND 215
Query: 76 ARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTW 135
+L + D + I + + ++HC+AG+SRSA++ +AY+MK MS DA+ +
Sbjct: 216 NYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRF 275
Query: 136 TKSRRPIIRPNNGFWEQLINYEFKL 160
K RRP I PN F QL+ YE L
Sbjct: 276 VKDRRPSISPNFNFLGQLLEYERSL 300
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 80.5 bits (197), Expect = 8e-16
Identities = 40/102 (39%), Positives = 60/102 (58%)
Query: 68 YIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSM 127
Y ++P TD+ L +F+ + I L+HC AGVSRSA++ +AYLMK+ M
Sbjct: 28 YKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRM 87
Query: 128 SLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMI 169
++ DA+ + K +RPII PN F QL+ +E L N T R++
Sbjct: 88 TMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRIL 129
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 80.5 bits (197), Expect = 8e-16
Identities = 40/102 (39%), Positives = 60/102 (58%)
Query: 68 YIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSM 127
Y ++P TD+ L +F+ + I L+HC AGVSRSA++ +AYLMK+ M
Sbjct: 28 YKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRM 87
Query: 128 SLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMI 169
++ DA+ + K +RPII PN F QL+ +E L N T R++
Sbjct: 88 TMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRIL 129
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 78.6 bits (192), Expect = 3e-15
Identities = 48/168 (28%), Positives = 81/168 (48%), Gaps = 2/168 (1%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
+++ L+L N + A D L N+IT I++ E + I Y+++PV D + +
Sbjct: 6 TKVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQPLLQDITYLRIPVADTPEVPIK 64
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
F + IH + G L+HC AG+SRS ++ AY+M + D K+ RPI
Sbjct: 65 KHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPI 124
Query: 143 IRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIYEKDLRMMISM 190
PN GF +QL + + + R + G P E++LR ++ +
Sbjct: 125 ANPNPGFRQQLEEFGW-ASSQKLRRQLEERFGESPFRDEEELRALLPL 171
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 73.6 bits (179), Expect = 1e-13
Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 9/147 (6%)
Query: 15 QQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-----FFEG--IQ 67
Q ++ ++ SLFL + AA DK L IT +VNA+ V F+ G ++
Sbjct: 39 QAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLE 98
Query: 68 YIKVPVTDARDSRLYDFFDPIADLIHT-IDMRQGRTLLHCMAGVSRSASLCLAYLMKYHS 126
Y + D L +F P+A I + + QGR L+HC GVSRSA+L LA+LM +
Sbjct: 99 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 158
Query: 127 MSLLDAHTWTKSRRPIIRPNNGFWEQL 153
M+L++A ++ R I PN+GF QL
Sbjct: 159 MTLVEAIQTVQAHRNIC-PNSGFLRQL 184
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 73.6 bits (179), Expect = 1e-13
Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 9/147 (6%)
Query: 15 QQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-----FFEG--IQ 67
Q ++ ++ SLFL + AA DK L IT +VNA+ V F+ G ++
Sbjct: 132 QAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLE 191
Query: 68 YIKVPVTDARDSRLYDFFDPIADLIHT-IDMRQGRTLLHCMAGVSRSASLCLAYLMKYHS 126
Y + D L +F P+A I + + QGR L+HC GVSRSA+L LA+LM +
Sbjct: 192 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 251
Query: 127 MSLLDAHTWTKSRRPIIRPNNGFWEQL 153
M+L++A ++ R I PN+GF QL
Sbjct: 252 MTLVEAIQTVQAHRNIC-PNSGFLRQL 277
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 73.6 bits (179), Expect = 1e-13
Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 9/147 (6%)
Query: 15 QQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-----FFEG--IQ 67
Q ++ ++ SLFL + AA DK L IT +VNA+ V F+ G ++
Sbjct: 89 QAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLE 148
Query: 68 YIKVPVTDARDSRLYDFFDPIADLIHT-IDMRQGRTLLHCMAGVSRSASLCLAYLMKYHS 126
Y + D L +F P+A I + + QGR L+HC GVSRSA+L LA+LM +
Sbjct: 149 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 208
Query: 127 MSLLDAHTWTKSRRPIIRPNNGFWEQL 153
M+L++A ++ R I PN+GF QL
Sbjct: 209 MTLVEAIQTVQAHRNIC-PNSGFLRQL 234
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 73.2 bits (178), Expect = 1e-13
Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
++I L++ N A D LS N++T I++ + EG++Y+ +P D+ L
Sbjct: 6 NKILPGLYIGNFKDARDAEQLSKNKVTHILSVH-DSARPMLEGVKYLCIPAADSPSQNLT 64
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
F IH +R L+HC+AGVSRS +L +AY+M DA ++ R
Sbjct: 65 RHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSC 124
Query: 143 IRPNNGFWEQLINYE 157
PN GF QL +E
Sbjct: 125 ANPNVGFQRQLQEFE 139
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 73.2 bits (178), Expect = 1e-13
Identities = 55/146 (37%), Positives = 78/146 (53%), Gaps = 13/146 (8%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFE-----GIQYIKVPVTDARD 78
++ L+L + AN++ L IT ++NAS E GI+Y+ V +A D
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGV---EAHD 120
Query: 79 SRLYDF---FDPIADLIH-TIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHT 134
S +D F AD IH + G+ L+HC GVSRSA+L LAYLM YH ++L++A
Sbjct: 121 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK 180
Query: 135 WTKSRRPIIRPNNGFWEQLINYEFKL 160
K R II PN GF QL+ + +L
Sbjct: 181 KVKDHRGII-PNRGFLRQLLALDRRL 205
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 71.6 bits (174), Expect = 4e-13
Identities = 50/154 (32%), Positives = 72/154 (46%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
S+I L+L + A + L NR+T I+N + E+ N + E Y V + D ++L
Sbjct: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLL 389
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
+ I + L+HC GVSRSA+ LAY MK + SL A + RPI
Sbjct: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
Query: 143 IRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNI 176
RPN GF QL Y+ L + + VG +
Sbjct: 450 ARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGV 483
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 71.2 bits (173), Expect = 5e-13
Identities = 48/156 (30%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Query: 6 SSFSSSQGVQQPSIYSFS--QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFF 63
SS + S G PS QI L+L + + +L I I+N + + N F
Sbjct: 227 SSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFE 286
Query: 64 EG--IQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYL 121
G Y ++P++D L FF I ++ L+HC+AG+SRS ++ +AYL
Sbjct: 287 HGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYL 346
Query: 122 MKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYE 157
M+ ++SL DA+ + K ++ I PN F QL+++E
Sbjct: 347 MQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFE 382
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 70.9 bits (172), Expect = 6e-13
Identities = 45/144 (31%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVV------NVFFEGIQYIKVPVTDAR 77
++ +LF+ + AN++ L IT ++NA+ + + + + + Y+ VP D
Sbjct: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
Query: 78 DSRLYDFFDPIADLIH-TIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWT 136
D + +F AD IH ++ + L+HC+ GVSRSA+L LAYLM + +SL A
Sbjct: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
Query: 137 KSRRPIIRPNNGFWEQLINYEFKL 160
+ R + PN GF QL + +L
Sbjct: 160 RQHRWVF-PNRGFLHQLCRLDQQL 182
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 67.8 bits (164), Expect = 5e-12
Identities = 44/135 (32%), Positives = 64/135 (47%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
S I L+L + A++ L + + I+N + E+ N F Y + V D + L
Sbjct: 310 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 369
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
++ I+ + L+HC GVSRSAS +AY MK L A+ + K +R I
Sbjct: 370 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 429
Query: 143 IRPNNGFWEQLINYE 157
RPN GF QL YE
Sbjct: 430 TRPNAGFMRQLSEYE 444
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 67.8 bits (164), Expect = 5e-12
Identities = 44/135 (32%), Positives = 64/135 (47%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
S I L+L + A++ L + + I+N + E+ N F Y + V D + L
Sbjct: 321 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 380
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
++ I+ + L+HC GVSRSAS +AY MK L A+ + K +R I
Sbjct: 381 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 440
Query: 143 IRPNNGFWEQLINYE 157
RPN GF QL YE
Sbjct: 441 TRPNAGFMRQLSEYE 455
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 67.8 bits (164), Expect = 5e-12
Identities = 44/135 (32%), Positives = 64/135 (47%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
S I L+L + A++ L + + I+N + E+ N F Y + V D + L
Sbjct: 310 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 369
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
++ I+ + L+HC GVSRSAS +AY MK L A+ + K +R I
Sbjct: 370 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 429
Query: 143 IRPNNGFWEQLINYE 157
RPN GF QL YE
Sbjct: 430 TRPNAGFMRQLSEYE 444
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 67.4 bits (163), Expect = 7e-12
Identities = 41/135 (30%), Positives = 67/135 (49%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
+QI +FL + A++ L + + I+N + E+ N F +Y + V D + L
Sbjct: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLL 368
Query: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
+++ I + L+HC GVSRSAS +AY MK + +L A+ + K RR +
Sbjct: 369 AYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTV 428
Query: 143 IRPNNGFWEQLINYE 157
+PN F QL Y+
Sbjct: 429 TKPNPSFMRQLEEYQ 443
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 66.6 bits (161), Expect = 1e-11
Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 6/163 (3%)
Query: 4 SASSFSSSQGVQQPSI---YSFS-QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVV 59
S S S+G P + SF QI +L+L + + + L+ I I+N + +
Sbjct: 182 SMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLP 241
Query: 60 NVFFEG--IQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLC 117
N F + Y ++P++D L FF + I + L+HC+AGVSRS ++
Sbjct: 242 NFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVT 301
Query: 118 LAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKL 160
+AYLM+ +SL DA+ K ++ I PN F QL+++E L
Sbjct: 302 VAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSL 344
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 64.7 bits (156), Expect = 5e-11
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 11/148 (7%)
Query: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNAS-------VEVVNVFFE--GIQYIKVPV 73
+++T +++ N A D L IT ++NA+ V F++ GI Y+ +
Sbjct: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
Query: 74 TDARDSRLYDFFDPIADLI-HTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDA 132
D ++ L +F+ AD I + + GR L+HC G SRS +L +AYLM M + A
Sbjct: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
Query: 133 HTWTKSRRPIIRPNNGFWEQLINYEFKL 160
+ + R I PN+GF QL +L
Sbjct: 151 LSIVRQNRE-IGPNDGFLAQLCQLNDRL 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,846,373
Number of Sequences: 37866
Number of extensions: 215969
Number of successful extensions: 577
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 509
Number of HSP's gapped (non-prelim): 64
length of query: 190
length of database: 18,247,518
effective HSP length: 96
effective length of query: 94
effective length of database: 14,612,382
effective search space: 1373563908
effective search space used: 1373563908
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.