Search of human proteins with 22538440

Search of human proteins with 22538440

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22538440 cathepsin C isoform b precursor [Homo sapiens]
         (137 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22538440 cathepsin C isoform b precursor [Homo sapiens]            283   4e-77
gi|167000671 cathepsin C isoform c precursor [Homo sapiens]           278   1e-75
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]       221   2e-58
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                       28   1.8  
gi|5453613 CD7 antigen precursor [Homo sapiens]                        27   5.3  
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap...    27   5.3  
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    27   5.3  
gi|71061446 zinc finger protein, X-linked [Homo sapiens]               27   5.3  
gi|27597078 TYRO3 protein tyrosine kinase [Homo sapiens]               27   6.9  
gi|5902158 ring finger protein 113A [Homo sapiens]                     27   6.9  
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]                     26   9.0  

>gi|22538440 cathepsin C isoform b precursor [Homo sapiens]
          Length = 137

 Score =  283 bits (723), Expect = 4e-77
 Identities = 137/137 (100%), Positives = 137/137 (100%)

Query: 1   MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 60
           MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ
Sbjct: 1   MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 60

Query: 61  EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG 120
           EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG
Sbjct: 61  EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG 120

Query: 121 TVGIYDLPHLRNKLVIK 137
           TVGIYDLPHLRNKLVIK
Sbjct: 121 TVGIYDLPHLRNKLVIK 137


>gi|167000671 cathepsin C isoform c precursor [Homo sapiens]
          Length = 141

 Score =  278 bits (711), Expect = 1e-75
 Identities = 134/136 (98%), Positives = 135/136 (99%)

Query: 1   MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 60
           MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ
Sbjct: 1   MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 60

Query: 61  EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG 120
           EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG
Sbjct: 61  EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG 120

Query: 121 TVGIYDLPHLRNKLVI 136
           TVGIYDLPHLRNKL +
Sbjct: 121 TVGIYDLPHLRNKLAM 136


>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
          Length = 463

 Score =  221 bits (562), Expect = 2e-58
 Identities = 106/106 (100%), Positives = 106/106 (100%)

Query: 1   MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 60
           MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ
Sbjct: 1   MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 60

Query: 61  EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFK 106
           EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFK
Sbjct: 61  EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFK 106


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 44  GSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLND 98
           G S +   V+ S+  PQ+ +V  Y    +  Y   G+S  + +   +GF + L+D
Sbjct: 446 GRSTTSLSVSWSIPPPQQSRVWKY----EVTYRKKGDSNSYNVRRTEGFSVTLDD 496


>gi|5453613 CD7 antigen precursor [Homo sapiens]
          Length = 240

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 5/72 (6%)

Query: 1  MGAGPSLLLAALLLLLSGD-----GAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCS 55
          M   P LLL  LLL L+        A       +CT + +  +      +SG  R +   
Sbjct: 1  MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLR 60

Query: 56 VMGPQEKKVVVY 67
           +GPQ + ++ Y
Sbjct: 61 QLGPQPQDIIYY 72


>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
           sapiens]
          Length = 525

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/23 (39%), Positives = 15/23 (65%)

Query: 77  DLGNSGHFTIIYNQGFEIVLNDY 99
           D G +G F  +Y+Q +E+  N+Y
Sbjct: 398 DFGPNGEFAYLYSQCYELTTNEY 420


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/23 (39%), Positives = 15/23 (65%)

Query: 77  DLGNSGHFTIIYNQGFEIVLNDY 99
           D G +G F  +Y+Q +E+  N+Y
Sbjct: 401 DFGPNGEFAYLYSQCYELTTNEY 423


>gi|71061446 zinc finger protein, X-linked [Homo sapiens]
          Length = 805

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 5/43 (11%)

Query: 44  GSSGSQRDVN-----CSVMGPQEKKVVVYLQKLDTAYDDLGNS 81
           GSSG   D       C V G   + + VY+ K D   DDLG +
Sbjct: 226 GSSGMTMDTESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGT 268


>gi|27597078 TYRO3 protein tyrosine kinase [Homo sapiens]
          Length = 890

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 13/74 (17%)

Query: 7  LLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVV- 65
          LLLAAL  LL  + A           L L+G  V    S G    +NCSV G +E  +  
Sbjct: 25 LLLAALASLLLPESAA--------AGLKLMGAPVKLTVSQGQPVKLNCSVEGMEEPDIQW 76

Query: 66 ----VYLQKLDTAY 75
                +Q LD  Y
Sbjct: 77 VKDGAVVQNLDQLY 90


>gi|5902158 ring finger protein 113A [Homo sapiens]
          Length = 343

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 10/21 (47%), Positives = 15/21 (71%)

Query: 44 GSSGSQRDVNCSVMGPQEKKV 64
          G SGS  D  C+V+ P++K+V
Sbjct: 41 GESGSSSDEGCTVVRPEKKRV 61


>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
          Length = 451

 Score = 26.2 bits (56), Expect = 9.0
 Identities = 12/36 (33%), Positives = 19/36 (52%), Gaps = 6/36 (16%)

Query: 102 FAFFKDVTDFISHLFMQLGT------VGIYDLPHLR 131
           F   KD+ D +  +F+ LGT       G++ LPH +
Sbjct: 314 FPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFK 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.142    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,247,102
Number of Sequences: 37866
Number of extensions: 210493
Number of successful extensions: 531
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 525
Number of HSP's gapped (non-prelim): 11
length of query: 137
length of database: 18,247,518
effective HSP length: 91
effective length of query: 46
effective length of database: 14,801,712
effective search space: 680878752
effective search space used: 680878752
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.