Search of human proteins with 11545855

Search of human proteins with 11545855

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11545855 ribokinase [Homo sapiens]
         (322 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11545855 ribokinase [Homo sapiens]                                 631   0.0  
gi|32484975 adenosine kinase isoform b [Homo sapiens]                  54   1e-07
gi|32484973 adenosine kinase isoform a [Homo sapiens]                  54   1e-07
gi|4557693 ketohexokinase isoform a [Homo sapiens]                     42   7e-04
gi|5670342 ketohexokinase isoform b [Homo sapiens]                     40   0.004
gi|4505701 pyridoxal kinase [Homo sapiens]                             34   0.20 
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]             33   0.26 
gi|209862851 plastin 3 [Homo sapiens]                                  31   1.7  
gi|7549809 plastin 3 [Homo sapiens]                                    31   1.7  
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]    30   2.2  
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]             30   3.8  
gi|223718250 plastin 1 [Homo sapiens]                                  29   4.9  
gi|223718246 plastin 1 [Homo sapiens]                                  29   4.9  
gi|94557308 L-3-hydroxyacyl-Coenzyme A dehydrogenase precursor [...    28   8.4  

>gi|11545855 ribokinase [Homo sapiens]
          Length = 322

 Score =  631 bits (1628), Expect = 0.0
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
           MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV
Sbjct: 1   MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60

Query: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
           QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI
Sbjct: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120

Query: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
           IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP
Sbjct: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180

Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
           AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG
Sbjct: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
           CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV
Sbjct: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300

Query: 301 SVQAAGTQSSYPYKKDLPLTLF 322
           SVQAAGTQSSYPYKKDLPLTLF
Sbjct: 301 SVQAAGTQSSYPYKKDLPLTLF 322


>gi|32484975 adenosine kinase isoform b [Homo sapiens]
          Length = 362

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 60/263 (22%), Positives = 109/263 (41%), Gaps = 30/263 (11%)

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
           +G D FG        +  +   + Y+  +  TGT +  +  + +++I  +A AN     +
Sbjct: 107 IGIDKFGEILKRKAAEAHVDAHY-YEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEK 165

Query: 135 DLRAAANVISRAKVMVCQ-----LEITPATSLEALTMARRSG-VKTLFNPAPAIADLDPQ 188
            L    N +   K  VC      L ++P + L+    A  +  + TL   AP I+    Q
Sbjct: 166 HLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFIS----Q 221

Query: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLKRGCQ---VVII 234
           FY  S        D+   NE+EA       G       +  +    L K   +   +VI 
Sbjct: 222 FYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIF 281

Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAV-DTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
           T G +  ++ +++E     +  +  K + DT GAGD+FVG   F      +  L + +  
Sbjct: 282 TQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 339

Query: 294 SNFIAAVSVQAAGTQSSYPYKKD 316
            ++ A++ ++  G   ++P K D
Sbjct: 340 GHYAASIIIRRTG--CTFPEKPD 360


>gi|32484973 adenosine kinase isoform a [Homo sapiens]
          Length = 345

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 60/263 (22%), Positives = 109/263 (41%), Gaps = 30/263 (11%)

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
           +G D FG        +  +   + Y+  +  TGT +  +  + +++I  +A AN     +
Sbjct: 90  IGIDKFGEILKRKAAEAHVDAHY-YEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEK 148

Query: 135 DLRAAANVISRAKVMVCQ-----LEITPATSLEALTMARRSG-VKTLFNPAPAIADLDPQ 188
            L    N +   K  VC      L ++P + L+    A  +  + TL   AP I+    Q
Sbjct: 149 HLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFIS----Q 204

Query: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLKRGCQ---VVII 234
           FY  S        D+   NE+EA       G       +  +    L K   +   +VI 
Sbjct: 205 FYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIF 264

Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAV-DTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
           T G +  ++ +++E     +  +  K + DT GAGD+FVG   F      +  L + +  
Sbjct: 265 TQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 322

Query: 294 SNFIAAVSVQAAGTQSSYPYKKD 316
            ++ A++ ++  G   ++P K D
Sbjct: 323 GHYAASIIIRRTG--CTFPEKPD 343


>gi|4557693 ketohexokinase isoform a [Homo sapiens]
          Length = 298

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 56/287 (19%), Positives = 108/287 (37%), Gaps = 39/287 (13%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
           E   ++ VG  + D++SL  + PK    I         GG  +N C   + LGA  + + 
Sbjct: 2   EEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMG 61

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
            +      +  +++L++  +   +T      +   A++I+N          +G+  +L  
Sbjct: 62  SMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINE--------ASGSRTILYY 113

Query: 134 EDLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAPAIADLDP--- 187
           +      +     KV + Q   + I    + E + M +R        P      +     
Sbjct: 114 DRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173

Query: 188 -------QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------ 234
                  Q +   DV   ++   ++   L   SA +A       +++G  +V        
Sbjct: 174 KPREELFQLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230

Query: 235 -TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
             LG +G ++ S   P P        + VDT GAGD+F  ++ F L+
Sbjct: 231 DALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 269


>gi|5670342 ketohexokinase isoform b [Homo sapiens]
          Length = 298

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 58/288 (20%), Positives = 109/288 (37%), Gaps = 41/288 (14%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
           E   ++ VG  + D++SL  + PK    I         GG  +N C   + LGA  + + 
Sbjct: 2   EEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMG 61

Query: 74  KVGKDSFGNDYIENLKQNDIS-TEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
            +      +  + + ++  +  ++  +Q+K     +  II N+ G   IV+   +   ++
Sbjct: 62  SMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVS 121

Query: 133 TEDLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAPAIADLDP-- 187
             D           KV + Q   + I    + E + M +R        P      +    
Sbjct: 122 ATDFE---------KVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEV 172

Query: 188 --------QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII----- 234
                   Q +   DV   ++   ++   L   SA +A       +++G  +V       
Sbjct: 173 EKPREELFQLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEG 229

Query: 235 --TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
              LG +G ++ S   P P        + VDT GAGD+F  ++ F L+
Sbjct: 230 ADALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 269


>gi|4505701 pyridoxal kinase [Homo sapiens]
          Length = 312

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 20/158 (12%)

Query: 171 GVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQ 230
           G  +++ P   +     +   L+D+   N+ EAE+L+G  + S  +A     +L   G  
Sbjct: 122 GEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPD 181

Query: 231 VVIIT-------LGAEGCVVL-SQTEPEPK--------HIPTEKVKAVDTTGAGDSFVGA 274
            V+IT        G+   +VL SQ    P          +   KV AV   G GD F   
Sbjct: 182 TVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLFAAM 240

Query: 275 LAFYLAYYPN---LSLEDMLNRSNFIAAVSVQAAGTQS 309
           L  +   +PN   ++ E  ++  + +   ++Q A  Q+
Sbjct: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQA 278


>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
          Length = 4116

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 33   SRLPKTGETIHGHKFFIGFGGKGANQCVQAAR-LGAMTSMVCKVGKDSFGNDYIENLKQN 91
            SR+ +  +   GH   +G GG G     + +  + A      ++ K+  GND+ E+LK  
Sbjct: 2417 SRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLK-- 2474

Query: 92   DISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
                +   Q   A   T  +  +N+ ++    V   N+LLNT D+
Sbjct: 2475 ----KIILQVGVATKSTVFLFADNQIKD-ESFVEDINMLLNTGDV 2514


>gi|209862851 plastin 3 [Homo sapiens]
          Length = 630

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 16/56 (28%), Positives = 29/56 (51%)

Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQ 188
           T+DL+ A +++ +A  + C+  +TPA  +        + V  LFN  PA+   + Q
Sbjct: 331 TDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQ 386


>gi|7549809 plastin 3 [Homo sapiens]
          Length = 630

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 16/56 (28%), Positives = 29/56 (51%)

Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQ 188
           T+DL+ A +++ +A  + C+  +TPA  +        + V  LFN  PA+   + Q
Sbjct: 331 TDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQ 386


>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
          Length = 731

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 7/105 (6%)

Query: 47  FFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDI---STEFTYQTKD 103
           +F+   GK A   +     GA T++     KD+  N Y +N    ++   +T+  YQT  
Sbjct: 3   WFVDLAGK-AEDLLNRVDQGAATALS---RKDNASNIYSKNTDYTELHQQNTDLIYQTGP 58

Query: 104 AATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKV 148
            +T  +S   N   Q   ++   AN+ + +     A++ +  A V
Sbjct: 59  KSTYISSAADNIRNQKATILAGTANVKVGSRTPVEASHPVENASV 103


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 3/42 (7%)

Query: 6   EPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKF 47
           EPQ + Q + AAV    SC T L +L S L  TG   H H F
Sbjct: 923 EPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTG---HWHDF 961


>gi|223718250 plastin 1 [Homo sapiens]
          Length = 629

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 3/67 (4%)

Query: 116 EGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL 175
           +G  I + ++G N    T DL+ A  ++  A  + C+  +TPA  +        + V  L
Sbjct: 315 DGPAIAIDLSGIN---ETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANL 371

Query: 176 FNPAPAI 182
           FN  P +
Sbjct: 372 FNTYPCL 378


>gi|223718246 plastin 1 [Homo sapiens]
          Length = 629

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 3/67 (4%)

Query: 116 EGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL 175
           +G  I + ++G N    T DL+ A  ++  A  + C+  +TPA  +        + V  L
Sbjct: 315 DGPAIAIDLSGIN---ETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANL 371

Query: 176 FNPAPAI 182
           FN  P +
Sbjct: 372 FNTYPCL 378


>gi|94557308 L-3-hydroxyacyl-Coenzyme A dehydrogenase precursor
           [Homo sapiens]
          Length = 314

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 28/110 (25%), Positives = 40/110 (36%), Gaps = 8/110 (7%)

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
           KV K  F     ENLK  D   E T  T   +T  AS++      +++V     NL +  
Sbjct: 76  KVAKKKFA----ENLKAGDEFVEKTLSTIATSTDAASVV---HSTDLVVEAIVENLKVKN 128

Query: 134 EDLRAAANVISRAKVMVCQLEITPATSL-EALTMARRSGVKTLFNPAPAI 182
           E  +      +   +          TS+  A T   R      FNP P +
Sbjct: 129 ELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVM 178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,743,961
Number of Sequences: 37866
Number of extensions: 423936
Number of successful extensions: 927
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 919
Number of HSP's gapped (non-prelim): 16
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.