Search of human proteins with 223972627

Search of human proteins with 223972627

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2
precursor [Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2 pre...   756   0.0  
gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1 precu...   456   e-128
gi|41872631 fatty acid synthase [Homo sapiens]                         57   4e-08
gi|148886668 zinc finger CCCH-type containing 12C [Homo sapiens]       35   0.084
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]                32   1.2  
gi|219842266 usherin isoform B [Homo sapiens]                          31   1.6  
gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform...    30   2.7  
gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform...    30   2.7  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    30   2.7  
gi|31543392 peroxisome proliferator-activated receptor gamma, co...    29   6.0  
gi|40548420 collectin sub-family member 11 isoform b [Homo sapiens]    29   6.0  
gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens]    29   6.0  

>gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2
           precursor [Homo sapiens]
          Length = 376

 Score =  756 bits (1951), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60
           MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH
Sbjct: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60

Query: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120
           LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI
Sbjct: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120

Query: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180
           MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV
Sbjct: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180

Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITAPDPEGEG 240
           PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITAPDPEGEG
Sbjct: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITAPDPEGEG 240

Query: 241 ALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGAT 300
           ALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGAT
Sbjct: 241 ALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGAT 300

Query: 301 GHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTN 360
           GHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTN
Sbjct: 301 GHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTN 360

Query: 361 SFGFGGTNATLCIAGL 376
           SFGFGGTNATLCIAGL
Sbjct: 361 SFGFGGTNATLCIAGL 376


>gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1
           precursor [Homo sapiens]
          Length = 459

 Score =  456 bits (1173), Expect = e-128
 Identities = 229/233 (98%), Positives = 230/233 (98%)

Query: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60
           MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH
Sbjct: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60

Query: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120
           LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI
Sbjct: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120

Query: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180
           MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV
Sbjct: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180

Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITA 233
           PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDA  + A
Sbjct: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVA 233



 Score =  311 bits (797), Expect = 6e-85
 Identities = 156/174 (89%), Positives = 158/174 (90%), Gaps = 4/174 (2%)

Query: 203 HAVSTACTTGAHAVGDSFRFIAHGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI 262
           HAV       A  +G    +   GDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI
Sbjct: 290 HAVQRRARIYAEVLG----YGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI 345

Query: 263 NAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQ 322
           NAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQ
Sbjct: 346 NAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQ 405

Query: 323 KLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 376
           KLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
Sbjct: 406 KLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 5/142 (3%)

Query: 236 PEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAE-NKAIKHLFKDHAYALAVS 294
           P G+   + + +  + AGV PE   YI AH T T +GD  E N   + L       L + 
Sbjct: 264 PSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIG 323

Query: 295 STKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDL---NYVPLKAQEWKT 351
           STK   GH   A+G    A   L+  +    P L+     PE        + +  Q    
Sbjct: 324 STKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPV 383

Query: 352 EKRFIGLTNSFGFGGTNATLCI 373
               +G+ NSFGFGG+N  + +
Sbjct: 384 RGGNVGI-NSFGFGGSNVHIIL 404



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 48/192 (25%), Positives = 81/192 (42%), Gaps = 26/192 (13%)

Query: 44  VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS----DEG 99
           VVI G+    P        WD LIGG    V +V ++ +     +   +PR S    D  
Sbjct: 4   VVIAGMSGKLPESENLQEFWDNLIGG----VDMVTDDDRRWKAGLYG-LPRRSGKLKDLS 58

Query: 100 QFNEQNF-VSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGM-GMIPL 157
           +F+   F V      +M     + +     A+ D G +P S      TGV +G+ G    
Sbjct: 59  RFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRG-THTGVWVGVSGSETS 117

Query: 158 EVVS---ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAH 214
           E +S   ET + +   G  +            M A ++S  +  +GP+ A+ TAC++   
Sbjct: 118 EALSRDPETLVGYSMVGCQRA-----------MMANRLSFFFDFRGPSIALDTACSSSLM 166

Query: 215 AVGDSFRFIAHG 226
           A+ ++++ I  G
Sbjct: 167 ALQNAYQAIHSG 178


>gi|148886668 zinc finger CCCH-type containing 12C [Homo sapiens]
          Length = 883

 Score = 35.4 bits (80), Expect = 0.084
 Identities = 44/201 (21%), Positives = 86/201 (42%), Gaps = 46/201 (22%)

Query: 83  SIPCSVAAY----VPRGSDEGQFN-----------EQNFVSKSDIKSMSSPTIMAIGAAE 127
           S+PCS  A     V RG+ + Q +           E+   +K+ +++ S P++++I A  
Sbjct: 469 SVPCSTKADSTSDVKRGAPKRQSDPSIRTQVYQDLEEKLPTKNKLETRSVPSLVSIPATS 528

Query: 128 LAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSE---TALNFQTKGYNKVSPFF-VPKI 183
            A       PQS    ++ G+  G+   P +   +    ++   TK +    P+   PK 
Sbjct: 529 TAK------PQSTTS-LSNGLPSGVHFPPQDQRPQGQYPSMMMATKNHGTPMPYEQYPKC 581

Query: 184 LVNMAAGQVSI-----RYKLKGPNH--------------AVSTACTT-GAHAVGDSFRFI 223
              +  G  S+        L GP                +V++ C++ G+ + G S  ++
Sbjct: 582 DSPVDIGYYSMLNAYSNLSLSGPRSPERRFSLDTDYRISSVASDCSSEGSMSCGSSDSYV 641

Query: 224 AHGDAGHITAPDPEGEGALRC 244
            + D  ++++PDP+ E  L+C
Sbjct: 642 GYNDRSYVSSPDPQLEENLKC 662


>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
          Length = 2769

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 11/33 (33%), Positives = 19/33 (57%)

Query: 326  PTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGL 358
            P  ++D  EP ++L +  +K QEW   K  +G+
Sbjct: 2490 PKPDMDAMEPSYELIHTQMKTQEWDNSKSILGV 2522


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 20/95 (21%), Positives = 41/95 (43%)

Query: 249  LKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAG 308
            +++  +   EI   + H T T +  A  ++ + HL     Y++ + +  G  G+L G   
Sbjct: 2749 IQNGDILSYEIHMPDPHITLTNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTE 2808

Query: 309  AVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVP 343
            ++    TT     Q + P   +  SE    +++ P
Sbjct: 2809 SLPTYVTTHPTVPQNVGPLSVIPLSESYVVISWQP 2843


>gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform a
            [Homo sapiens]
          Length = 2436

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 6/141 (4%)

Query: 194  IRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITAP----DPEGEGALRCMAAAL 249
            ++YK  G    +ST     A  +GD    I+HG      +P       G+G    +    
Sbjct: 1167 LKYK-PGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRP 1225

Query: 250  KDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 309
             + G  P+E    ++     PL   +E +  + + K  A  L VS T     ++L +  A
Sbjct: 1226 AEPG-GPQEPGLASSPPGRAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAA 1284

Query: 310  VEAAFTTLACYYQKLPPTLNL 330
             + AF  L  + ++    L+L
Sbjct: 1285 KKGAFERLFQHLERSLDALHL 1305


>gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform b
            [Homo sapiens]
          Length = 2466

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 6/141 (4%)

Query: 194  IRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITAP----DPEGEGALRCMAAAL 249
            ++YK  G    +ST     A  +GD    I+HG      +P       G+G    +    
Sbjct: 1197 LKYK-PGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRP 1255

Query: 250  KDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 309
             + G  P+E    ++     PL   +E +  + + K  A  L VS T     ++L +  A
Sbjct: 1256 AEPG-GPQEPGLASSPPGRAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAA 1314

Query: 310  VEAAFTTLACYYQKLPPTLNL 330
             + AF  L  + ++    L+L
Sbjct: 1315 KKGAFERLFQHLERSLDALHL 1335


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 14/29 (48%), Positives = 18/29 (62%)

Query: 229 GHITAPDPEGEGALRCMAAALKDAGVQPE 257
           GH+T+  P+  G L+C A  L  AGVQ E
Sbjct: 399 GHVTSMQPKEPGPLQCEAKPLGKAGVQLE 427


>gi|31543392 peroxisome proliferator-activated receptor gamma,
           coactivator 1 beta [Homo sapiens]
          Length = 1023

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 2/61 (3%)

Query: 231 ITAPDPEGEGALRCMAAALKDAGVQPEEISYIN--AHATSTPLGDAAENKAIKHLFKDHA 288
           ++ P PEG        AA K     PE    ++   HAT+ P   A + +     F DH 
Sbjct: 634 LSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHD 693

Query: 289 Y 289
           Y
Sbjct: 694 Y 694


>gi|40548420 collectin sub-family member 11 isoform b [Homo sapiens]
          Length = 268

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 7/100 (7%)

Query: 226 GDAGHITAPDPEGEGALRCMAAALKDA-GVQPEEISYINAHATSTPLGDA----AENKAI 280
           GD+G I  P P GE  L C  + L+ A G    ++S + +         A     E+K  
Sbjct: 92  GDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKIY 151

Query: 281 KHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACY 320
             + ++  YA A  S +G  G L  +    EAA   +A Y
Sbjct: 152 LLVKEEKRYADAQLSCQGRGGTL--SMPKDEAANGLMAAY 189


>gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens]
          Length = 271

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 7/100 (7%)

Query: 226 GDAGHITAPDPEGEGALRCMAAALKDA-GVQPEEISYINAHATSTPLGDA----AENKAI 280
           GD+G I  P P GE  L C  + L+ A G    ++S + +         A     E+K  
Sbjct: 95  GDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKIY 154

Query: 281 KHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACY 320
             + ++  YA A  S +G  G L  +    EAA   +A Y
Sbjct: 155 LLVKEEKRYADAQLSCQGRGGTL--SMPKDEAANGLMAAY 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,897,773
Number of Sequences: 37866
Number of extensions: 604893
Number of successful extensions: 1356
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1342
Number of HSP's gapped (non-prelim): 16
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.