BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223468576 mitochondrial carrier protein-like [Homo sapiens] (157 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223468576 mitochondrial carrier protein-like [Homo sapiens] 319 5e-88 gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 129 8e-31 gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 107 3e-24 gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 86 1e-17 gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 86 2e-17 gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 69 1e-12 gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 56 1e-08 gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 55 2e-08 gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 55 2e-08 gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 55 3e-08 gi|11225256 uncoupling protein 1 [Homo sapiens] 54 7e-08 gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 53 9e-08 gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 53 9e-08 gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 52 2e-07 gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 52 3e-07 gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 52 3e-07 gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 52 3e-07 gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens] 51 4e-07 gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 50 6e-07 gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 50 1e-06 gi|157388925 solute carrier family 25, member 38 [Homo sapiens] 50 1e-06 gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 49 2e-06 gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 49 2e-06 gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 49 2e-06 gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 49 2e-06 gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 49 2e-06 gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 48 3e-06 gi|13259541 uncoupling protein 2 [Homo sapiens] 48 3e-06 gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 47 9e-06 gi|13899342 solute carrier [Homo sapiens] 47 9e-06 >gi|223468576 mitochondrial carrier protein-like [Homo sapiens] Length = 157 Score = 319 bits (818), Expect = 5e-88 Identities = 157/157 (100%), Positives = 157/157 (100%) Query: 1 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFK 60 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFK Sbjct: 1 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFK 60 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL Sbjct: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 Query: 121 GGPVDLIKIRLQMQTQPFRDGGEHRMTTVFPGPHLCM 157 GGPVDLIKIRLQMQTQPFRDGGEHRMTTVFPGPHLCM Sbjct: 121 GGPVDLIKIRLQMQTQPFRDGGEHRMTTVFPGPHLCM 157 >gi|116235462 solute carrier family 25, member 45 isoform a [Homo sapiens] Length = 288 Score = 129 bits (325), Expect = 8e-31 Identities = 66/132 (50%), Positives = 84/132 (63%), Gaps = 1/132 (0%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFKGMSFP 65 +E+F AGWI GA +++GHP DTVK RLQ Y + C+ +YR ES+ GFFKGMSFP Sbjct: 3 VEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKIYRHESLLGFFKGMSFP 62 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVD 125 +ASIAV NSV+FGV+SNT L+ E A PP + + LA G + P D Sbjct: 63 IASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPP-SYMHIFLAGCTGGFLQAYCLAPFD 121 Query: 126 LIKIRLQMQTQP 137 LIK+RLQ QT+P Sbjct: 122 LIKVRLQNQTEP 133 Score = 42.0 bits (97), Expect = 2e-04 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 18/136 (13%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQ------AGVG-----YGNTLSCIRVVYRRESMFG 57 F AG GG P D +K RLQ A G Y + C ++R E G Sbjct: 103 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 162 Query: 58 FFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVS 117 F+G ++ + ++ G++ T L + PE P + + +L+A AG+ S Sbjct: 163 LFRGAW----ALTLRDTPTVGIYFITYEGLCRQYT--PEGQNPSSAT-VLVAGGFAGIAS 215 Query: 118 VGLGGPVDLIKIRLQM 133 P+D+IK R+QM Sbjct: 216 WVAATPLDMIKSRMQM 231 Score = 36.6 bits (83), Expect = 0.009 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQA-GVG---YGNTLSCIRVVYRRESMFGFFKGMSFPL 66 AG G AS + PLD +K+R+Q G+ Y L C+ R+E + FF+G++ Sbjct: 207 AGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINS 266 Query: 67 ASIAVYNSVVF 77 A N+V F Sbjct: 267 ARAFPVNAVTF 277 >gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] Length = 308 Score = 107 bits (268), Expect = 3e-24 Identities = 53/129 (41%), Positives = 80/129 (62%), Gaps = 2/129 (1%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFKGMSFPLA 67 DF AG IGG V VG+PLDTVK R+Q Y C+R Y RE ++GF++G+S P+ Sbjct: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPVC 61 Query: 68 SIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLI 127 ++++ +SV FG + + + + R G P+A P T +D+ L+ +G+V V L P ++ Sbjct: 62 TVSLVSSVSFGTYRHCLAHICRLRYGNPDAKP--TKADITLSGCASGLVRVFLTSPTEVA 119 Query: 128 KIRLQMQTQ 136 K+RLQ QTQ Sbjct: 120 KVRLQTQTQ 128 Score = 35.4 bits (80), Expect = 0.020 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 39 YGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEAS 98 Y L C+ V R E + G +KG S + + F ++ +LS P+ Sbjct: 159 YRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPD-- 216 Query: 99 PPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQTQ 136 + +L+A AGV++ + P+D+IK RLQ Q Sbjct: 217 ----VPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQ 250 Score = 34.3 bits (77), Expect = 0.045 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 4/79 (5%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQA-GVG---YGNTLSCIRVVYRRESMFGFFKGMSFPL 66 AG G + V P+D +K+RLQA G G Y L C+ R E FKG+ Sbjct: 223 AGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNC 282 Query: 67 ASIAVYNSVVFGVFSNTQR 85 N VVF + R Sbjct: 283 CRAFPVNMVVFVAYEAVLR 301 >gi|116235466 solute carrier family 25, member 45 isoform b [Homo sapiens] Length = 246 Score = 85.9 bits (211), Expect = 1e-17 Identities = 46/89 (51%), Positives = 57/89 (64%), Gaps = 1/89 (1%) Query: 49 VYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLL 108 +YR ES+ GFFKGMSFP+ASIAV NSV+FGV+SNT L+ E A PP + + L Sbjct: 4 IYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPP-SYMHIFL 62 Query: 109 ASMVAGVVSVGLGGPVDLIKIRLQMQTQP 137 A G + P DLIK+RLQ QT+P Sbjct: 63 AGCTGGFLQAYCLAPFDLIKVRLQNQTEP 91 Score = 42.0 bits (97), Expect = 2e-04 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 18/136 (13%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQ------AGVG-----YGNTLSCIRVVYRRESMFG 57 F AG GG P D +K RLQ A G Y + C ++R E G Sbjct: 61 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 120 Query: 58 FFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVS 117 F+G ++ + ++ G++ T L + PE P + + +L+A AG+ S Sbjct: 121 LFRGAW----ALTLRDTPTVGIYFITYEGLCRQYT--PEGQNPSSAT-VLVAGGFAGIAS 173 Query: 118 VGLGGPVDLIKIRLQM 133 P+D+IK R+QM Sbjct: 174 WVAATPLDMIKSRMQM 189 Score = 36.6 bits (83), Expect = 0.009 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQA-GVG---YGNTLSCIRVVYRRESMFGFFKGMSFPL 66 AG G AS + PLD +K+R+Q G+ Y L C+ R+E + FF+G++ Sbjct: 165 AGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINS 224 Query: 67 ASIAVYNSVVF 77 A N+V F Sbjct: 225 ARAFPVNAVTF 235 >gi|86198310 solute carrier family 25, member 29 [Homo sapiens] Length = 303 Score = 85.5 bits (210), Expect = 2e-17 Identities = 52/131 (39%), Positives = 69/131 (52%), Gaps = 15/131 (11%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGV----GYGNTLSCIRVVYRRESMFGFFKGMS 63 DF AG GG A V+VGHP DTVK RLQ Y TL C + + ++ES+ G +KG+ Sbjct: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63 Query: 64 FPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGP 123 PL + N++VFGV NT R L SP + LA AG + + P Sbjct: 64 SPLMGLTFINALVFGVQGNTLRALGHD-------SP----LNQFLAGAAAGAIQCVICCP 112 Query: 124 VDLIKIRLQMQ 134 ++L K RLQ+Q Sbjct: 113 MELAKTRLQLQ 123 Score = 52.0 bits (123), Expect = 2e-07 Identities = 44/132 (33%), Positives = 63/132 (47%), Gaps = 11/132 (8%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQ---AGVG--YGNTLSCIRVVYRRESMFGFFK 60 L F AG GA ++ P++ KTRLQ AG Y +L C+ +Y E + G + Sbjct: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNR 152 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 GM S + + FGV+ T L++ EP + LLLA +G+VS Sbjct: 153 GM----VSTLLRETPSFGVYFLTYDALTRALGCEP--GDRLLVPKLLLAGGTSGIVSWLS 206 Query: 121 GGPVDLIKIRLQ 132 PVD++K RLQ Sbjct: 207 TYPVDVVKSRLQ 218 Score = 37.4 bits (85), Expect = 0.005 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 6/95 (6%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQA-----GVGYGNTLSCIRVVYRRESMFGFFKGMSFP 65 AG G S + +P+D VK+RLQA Y L C+ YR E F +G++ Sbjct: 195 AGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLAST 254 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCG-EPEASP 99 L N+ F + + G E EA P Sbjct: 255 LLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVP 289 Score = 29.6 bits (65), Expect = 1.1 Identities = 13/28 (46%), Positives = 18/28 (64%) Query: 108 LASMVAGVVSVGLGGPVDLIKIRLQMQT 135 LA GV V +G P D +K+RLQ+Q+ Sbjct: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQS 33 >gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] Length = 301 Score = 69.3 bits (168), Expect = 1e-12 Identities = 50/152 (32%), Positives = 69/152 (45%), Gaps = 22/152 (14%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVG--------YGNTLSCIRVVYRRESMFG 57 L++ AG GG V VGHPLDTVK RLQ Y T C R RE + G Sbjct: 11 LKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITG 70 Query: 58 FFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLS--DLLLASMVAGV 115 ++GM+ P+ + +V F F ++ +H P LS L A M++GV Sbjct: 71 LYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKH--------PEDVLSYPQLFAAGMLSGV 122 Query: 116 VSVGLGGPVDLIKIRLQMQTQPFRDGGEHRMT 147 + G+ P + IK LQ+Q GE + T Sbjct: 123 FTTGIMTPGERIKCLLQIQA----SSGESKYT 150 Score = 42.7 bits (99), Expect = 1e-04 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 9/129 (6%) Query: 9 FAAGWIGGAASVIVGHPLDTVKT--RLQAGVG---YGNTLSCIRVVYRRESMFGFFKGMS 63 FAAG + G + + P + +K ++QA G Y TL C + +Y+ + G +KG Sbjct: 114 FAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTV 173 Query: 64 FPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGP 123 L + + F + + + E S PR +L+A +AG+ + + P Sbjct: 174 LTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPR----ILVAGGIAGIFNWAVAIP 229 Query: 124 VDLIKIRLQ 132 D++K R Q Sbjct: 230 PDVLKSRFQ 238 >gi|13994341 solute carrier family 25 member 2 [Homo sapiens] Length = 301 Score = 56.2 bits (134), Expect = 1e-08 Identities = 41/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVG-YGNTLSCIRVVYRRESMFGFFKGMSFPL 66 D AG GG A V+ G P DT+K ++Q Y C Y + + GF+KG L Sbjct: 12 DLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGPAL 71 Query: 67 ASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLA---SMVAGVVSVGLGGP 123 + NSV+F + Q+F+ + + +A LSDL A S + ++ L P Sbjct: 72 MAYVAENSVLFMCYGFCQQFVRKVAGMDKQAK----LSDLQTAAAGSFASAFAALAL-CP 126 Query: 124 VDLIKIRLQ 132 +L+K RLQ Sbjct: 127 TELVKCRLQ 135 Score = 38.9 bits (89), Expect = 0.002 Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 15/147 (10%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQA----------GVGYGNTLSCIRVVYRRESM 55 L+ AAG A + + P + VK RLQ + S ++ + +++ Sbjct: 107 LQTAAAGSFASAFAALALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGP 166 Query: 56 FGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGV 115 GF+ G+S L FG + ++ F + R + E P L+L+ VAG+ Sbjct: 167 LGFYHGLSSTLLQEVPGYFFFFGGYELSRSFFASGR-SKDELGPVH----LMLSGGVAGI 221 Query: 116 VSVGLGGPVDLIKIRLQMQTQPFRDGG 142 + PVD IK R+Q+ + + G Sbjct: 222 CLWLVVFPVDCIKSRIQVLSMYGKQAG 248 Score = 29.3 bits (64), Expect = 1.4 Identities = 16/80 (20%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAGVGYGNT---LSCIRVVYRRESMFGFFKGMSFPLA 67 +G + G +V P+D +K+R+Q YG + + V R E + + G+ + Sbjct: 215 SGGVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFIGTLLSVVRNEGIVALYSGLKATMI 274 Query: 68 SIAVYNSVVFGVFSNTQRFL 87 N +F + +++ + Sbjct: 275 RAIPANGALFVAYEYSRKMM 294 >gi|157388991 solute carrier family 25, member 36 isoform b [Homo sapiens] Length = 310 Score = 55.5 bits (132), Expect = 2e-08 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 31/157 (19%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQ----------------AGVGYGNTLS-----CIRVV 49 AG GG I+ PL+ VKTRLQ AG +S C++V+ Sbjct: 12 AGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVI 71 Query: 50 YRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLA 109 +E F+G+ L +A ++ F +SN + L+ + P + +++ Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN-------DVFDPDSTQVHMIS 124 Query: 110 SMVAGVVSVGLGGPVDLIKIRLQMQTQPFRDGGEHRM 146 + +AG ++ P+ LIK RLQ+ R+ GE RM Sbjct: 125 AAMAGFTAITATNPIWLIKTRLQLDA---RNRGERRM 158 Score = 37.4 bits (85), Expect = 0.005 Identities = 30/137 (21%), Positives = 66/137 (48%), Gaps = 13/137 (9%) Query: 14 IGGAASVIVGHPLDTVKTRLQA-----GVGYGNTLSCIRVVYRRESMFGFFKGMSFPLAS 68 + G ++ +P+ +KTRLQ G C+R VY+ + + GF++GMS A Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186 Query: 69 IAVYNSVVFGVFSNTQRFLSQHRCG---EPEASPPRTLSD---LLLASMVAGVVSVGLGG 122 I+ + F ++ + ++ L +++ E + + SD ++LA+ + + + Sbjct: 187 IS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAY 245 Query: 123 PVDLIKIRLQMQTQPFR 139 P +++ RL+ + +R Sbjct: 246 P-HVVRTRLREEGTKYR 261 >gi|157388989 solute carrier family 25, member 36 isoform a [Homo sapiens] Length = 311 Score = 55.5 bits (132), Expect = 2e-08 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 31/157 (19%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQ----------------AGVGYGNTLS-----CIRVV 49 AG GG I+ PL+ VKTRLQ AG +S C++V+ Sbjct: 12 AGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVI 71 Query: 50 YRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLA 109 +E F+G+ L +A ++ F +SN + L+ + P + +++ Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN-------DVFDPDSTQVHMIS 124 Query: 110 SMVAGVVSVGLGGPVDLIKIRLQMQTQPFRDGGEHRM 146 + +AG ++ P+ LIK RLQ+ R+ GE RM Sbjct: 125 AAMAGFTAITATNPIWLIKTRLQLDA---RNRGERRM 158 Score = 42.0 bits (97), Expect = 2e-04 Identities = 30/137 (21%), Positives = 67/137 (48%), Gaps = 12/137 (8%) Query: 14 IGGAASVIVGHPLDTVKTRLQA-----GVGYGNTLSCIRVVYRRESMFGFFKGMSFPLAS 68 + G ++ +P+ +KTRLQ G C+R VY+ + + GF++GMS A Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186 Query: 69 IAVYNSVVFGVFSNTQRFLSQHRCG---EPEASPPRTLSD---LLLASMVAGVVSVGLGG 122 I+ + F ++ + ++ L +++ E + + SD ++LA+ + + + Sbjct: 187 IS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAY 245 Query: 123 PVDLIKIRLQMQTQPFR 139 P ++++ RL+ + +R Sbjct: 246 PHEVVRTRLREEGTKYR 262 >gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 [Homo sapiens] Length = 299 Score = 54.7 bits (130), Expect = 3e-08 Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 14/136 (10%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAGV------GYGNTLSCIRVVYRRESMFGFFKGMSF 64 AG G + + HPLD VKTR Q Y + + R++++ E +FGF+KG+ Sbjct: 19 AGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILP 78 Query: 65 PLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPV 124 P+ + +V F F ++ L G SP T + +A + +G+ + P Sbjct: 79 PILAETPKRAVKFFTFEQYKKLL-----GYVSLSPALTFA---IAGLGSGLTEAIVVNPF 130 Query: 125 DLIKIRLQMQTQPFRD 140 +++K+ LQ F + Sbjct: 131 EVVKVGLQANRNTFAE 146 Score = 42.0 bits (97), Expect = 2e-04 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 12/128 (9%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAG----VGYGNTLSCIRVVYRRES--MFGFFKGMSF 64 AG G IV +P + VK LQA +T+ R + ++E + G KG++ Sbjct: 115 AGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTA 174 Query: 65 PLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPV 124 L V+N V FG + N + + ++ +P R LL+ +A V+++ P Sbjct: 175 TLGRHGVFNMVYFGFYYNVKNMIPVNK--DPILEFWRKFGIGLLSGTIASVINI----PF 228 Query: 125 DLIKIRLQ 132 D+ K R+Q Sbjct: 229 DVAKSRIQ 236 Score = 33.9 bits (76), Expect = 0.058 Identities = 18/88 (20%), Positives = 38/88 (43%), Gaps = 6/88 (6%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQ------AGVGYGNTLSCIRVVYRRESMFGFFKGM 62 F G + G + ++ P D K+R+Q + Y + VY+ E + +KG+ Sbjct: 211 FGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGL 270 Query: 63 SFPLASIAVYNSVVFGVFSNTQRFLSQH 90 + + +V+ V+ T +L ++ Sbjct: 271 LPKIMRLGPGGAVMLLVYEYTYSWLQEN 298 Score = 31.2 bits (69), Expect = 0.38 Identities = 16/41 (39%), Positives = 25/41 (60%) Query: 94 EPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQ 134 +PE S R S ++A AG+V + L P+D++K R Q+Q Sbjct: 4 KPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQ 44 >gi|11225256 uncoupling protein 1 [Homo sapiens] Length = 307 Score = 53.5 bits (127), Expect = 7e-08 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 15/135 (11%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQAG--------VGYGNTLSCIRVVYRRESMFGFFK 60 F+AG I + ++ PLDT K RLQ + Y L I V + E + Sbjct: 18 FSAG-IAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYS 76 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 G+ L S+ G++ Q FL+ + E +P +L +LA + G V+V + Sbjct: 77 GLPAGLQRQISSASLRIGLYDTVQEFLTAGK----ETAP--SLGSKILAGLTTGGVAVFI 130 Query: 121 GGPVDLIKIRLQMQT 135 G P +++K+RLQ Q+ Sbjct: 131 GQPTEVVKVRLQAQS 145 Score = 41.6 bits (96), Expect = 3e-04 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 13/127 (10%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQA-----GVG--YGNTLSCIRVVYRRESMFGFFKGMS 63 AG G +V +G P + VK RLQA G+ Y T + R++ E + G +KG + Sbjct: 119 AGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTT 178 Query: 64 FPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGP 123 L + N + + ++ + L+++++AG + + P Sbjct: 179 PNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCH------LVSALIAGFCATAMSSP 232 Query: 124 VDLIKIR 130 VD++K R Sbjct: 233 VDVVKTR 239 Score = 38.1 bits (87), Expect = 0.003 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Query: 14 IGGAASVIVGHPLDTVKTR-LQAGVG-YGNTLSCIRVVYRRESMFGFFKGMSFPLASIAV 71 I G + + P+D VKTR + + G Y + +C V+ E FFKG+ + Sbjct: 221 IAGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGS 280 Query: 72 YNSVVFGVFSNTQRFLSQHR 91 +N ++F F +R LS+ R Sbjct: 281 WNVIMFVCFEQLKRELSKSR 300 >gi|55749577 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 [Homo sapiens] Length = 298 Score = 53.1 bits (126), Expect = 9e-08 Identities = 34/135 (25%), Positives = 61/135 (45%), Gaps = 15/135 (11%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTL-------SCIRVVYRRESMFGFFK 60 + A+G GA S+ +PLD +TRL A VG G CI +++ + + G ++ Sbjct: 116 NLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQ 175 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 G + + I +Y + FGV+ + L P+ ++A V V + + Sbjct: 176 GFNVSVQGIIIYRAAYFGVYDTAKGML-------PDPKNVHIFVSWMIAQSVTAVAGL-V 227 Query: 121 GGPVDLIKIRLQMQT 135 P D ++ R+ MQ+ Sbjct: 228 SYPFDTVRRRMMMQS 242 Score = 31.6 bits (70), Expect = 0.29 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 7/52 (13%) Query: 17 AASVIVGHPLDTVKTRLQ-------AGVGYGNTLSCIRVVYRRESMFGFFKG 61 A + +V +P DTV+ R+ A + Y T+ C R + + E FFKG Sbjct: 222 AVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKG 273 Score = 28.1 bits (61), Expect = 3.2 Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 9/65 (13%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQ---------AGVGYGNTLSCIRVVYRRESMF 56 L+DF AG + A S P++ VK LQ A Y + C+ + + + Sbjct: 9 LKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 68 Query: 57 GFFKG 61 F++G Sbjct: 69 SFWRG 73 >gi|156071462 solute carrier family 25, member A6 [Homo sapiens] Length = 298 Score = 53.1 bits (126), Expect = 9e-08 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 15/135 (11%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTL-------SCIRVVYRRESMFGFFK 60 + A+G GA S+ +PLD +TRL A VG T C+ + + + + G ++ Sbjct: 116 NLASGGAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQ 175 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 G S + I +Y + FGV+ + L P+ + ++A V V V + Sbjct: 176 GFSVSVQGIIIYRAAYFGVYDTAKGML-------PDPKNTHIVVSWMIAQTVTAVAGV-V 227 Query: 121 GGPVDLIKIRLQMQT 135 P D ++ R+ MQ+ Sbjct: 228 SYPFDTVRRRMMMQS 242 Score = 34.3 bits (77), Expect = 0.045 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 7/52 (13%) Query: 17 AASVIVGHPLDTVKTRLQ-------AGVGYGNTLSCIRVVYRRESMFGFFKG 61 A + +V +P DTV+ R+ A + Y T+ C R ++R E FFKG Sbjct: 222 AVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKG 273 Score = 27.3 bits (59), Expect = 5.5 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 7 EDFAAGWIGGAASVIVGHPLDTVKTRLQ---------AGVGYGNTLSCIRVVYRRESMFG 57 +DF AG I A S P++ VK LQ A Y + CI + + + + Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69 Query: 58 FFKG 61 F++G Sbjct: 70 FWRG 73 >gi|27544933 solute carrier family 25, member 16 [Homo sapiens] Length = 332 Score = 52.0 bits (123), Expect = 2e-07 Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 12/137 (8%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAGV----GYGNTLSCIRVVYRRES-MFGFFKGMSFP 65 AG + G +VI +PLD V+ RL V Y + + +Y +E FGF++G+ Sbjct: 136 AGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPT 195 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHR---CGEPEASPPRTL----SDLLLASMVAGVVSV 118 + +A Y V F F + H G P + P L LL VAG ++ Sbjct: 196 ILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQ 255 Query: 119 GLGGPVDLIKIRLQMQT 135 + P D+ + R+Q+ T Sbjct: 256 TISYPFDVTRRRMQLGT 272 Score = 50.4 bits (119), Expect = 6e-07 Identities = 42/157 (26%), Positives = 67/157 (42%), Gaps = 31/157 (19%) Query: 4 FQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTL---SCIRVVYRRESMFGFFK 60 + L F AG I G + PLD VK LQA + L S +R V ++E G +K Sbjct: 35 YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYK 94 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQ--------HRCGEPEASPPRTLSDLLLASMV 112 G + I Y ++ F F + + ++ HR L+A + Sbjct: 95 GNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHR---------------LMAGSM 139 Query: 113 AGVVSVGLGGPVDLIKIRLQMQTQPFRDGGEHRMTTV 149 AG+ +V P+D++++RL Q + GEH T + Sbjct: 140 AGMTAVICTYPLDMVRVRLAFQVK-----GEHSYTGI 171 Score = 26.6 bits (57), Expect = 9.3 Identities = 17/82 (20%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 12 GWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCI------RVVYRRESM-FGFFKGMSF 64 G + GA + + +P D + R+Q G C+ + VY + G ++G+S Sbjct: 247 GGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSL 306 Query: 65 PLASIAVYNSVVFGVFSNTQRF 86 +V F + ++F Sbjct: 307 NYIRCIPSQAVAFTTYELMKQF 328 >gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo sapiens] Length = 675 Score = 51.6 bits (122), Expect = 3e-07 Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 16/134 (11%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQ------AGVG---YGNTLSCIRVVYRRESMFGFF 59 F G + GA +P+D VKTR+Q + VG Y N+ C + V R E FG + Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391 Query: 60 KGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVG 119 +G+ L +A ++ V ++ R H+ G S P L+ +LA AG V Sbjct: 392 RGLLPQLLGVAPEKAIKLTV-NDFVRDKFMHKDG----SVP--LAAEILAGGCAGGSQVI 444 Query: 120 LGGPVDLIKIRLQM 133 P++++KIRLQ+ Sbjct: 445 FTNPLEIVKIRLQV 458 Score = 50.8 bits (120), Expect = 5e-07 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAG--VGYGNTLSCIRVVYRRESMFGFFKGMSFP 65 + AG G + VI +PL+ VK RLQ + G +S + VV R FG +KG Sbjct: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVV-RDLGFFGIYKGAKAC 489 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVD 125 ++++ F +++ + + + + SP LLLA +AG+ + L P D Sbjct: 490 FLRDIPFSAIYFPCYAHVKASFANE---DGQVSP----GSLLLAGAIAGMPAASLVTPAD 542 Query: 126 LIKIRLQM 133 +IK RLQ+ Sbjct: 543 VIKTRLQV 550 Score = 32.7 bits (73), Expect = 0.13 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 5/56 (8%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAGVGYGNT-----LSCIRVVYRRESMFGFFKG 61 AG I G + + P D +KTRLQ G T + C R + R E +KG Sbjct: 526 AGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKG 581 >gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo sapiens] Length = 676 Score = 51.6 bits (122), Expect = 3e-07 Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 16/134 (11%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQ------AGVG---YGNTLSCIRVVYRRESMFGFF 59 F G + GA +P+D VKTR+Q + VG Y N+ C + V R E FG + Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392 Query: 60 KGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVG 119 +G+ L +A ++ V ++ R H+ G S P L+ +LA AG V Sbjct: 393 RGLLPQLLGVAPEKAIKLTV-NDFVRDKFMHKDG----SVP--LAAEILAGGCAGGSQVI 445 Query: 120 LGGPVDLIKIRLQM 133 P++++KIRLQ+ Sbjct: 446 FTNPLEIVKIRLQV 459 Score = 50.8 bits (120), Expect = 5e-07 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAG--VGYGNTLSCIRVVYRRESMFGFFKGMSFP 65 + AG G + VI +PL+ VK RLQ + G +S + VV R FG +KG Sbjct: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVV-RDLGFFGIYKGAKAC 490 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVD 125 ++++ F +++ + + + + SP LLLA +AG+ + L P D Sbjct: 491 FLRDIPFSAIYFPCYAHVKASFANE---DGQVSP----GSLLLAGAIAGMPAASLVTPAD 543 Query: 126 LIKIRLQM 133 +IK RLQ+ Sbjct: 544 VIKTRLQV 551 Score = 32.7 bits (73), Expect = 0.13 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 5/56 (8%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAGVGYGNT-----LSCIRVVYRRESMFGFFKG 61 AG I G + + P D +KTRLQ G T + C R + R E +KG Sbjct: 527 AGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKG 582 >gi|156071459 solute carrier family 25, member 5 [Homo sapiens] Length = 298 Score = 51.6 bits (122), Expect = 3e-07 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 15/135 (11%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVG-------YGNTLSCIRVVYRRESMFGFFK 60 + A+G GA S+ +PLD +TRL A VG + C+ +Y+ + + G ++ Sbjct: 116 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 175 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 G + + I +Y + FG++ + L P+ + ++A V V + Sbjct: 176 GFNVSVQGIIIYRAAYFGIYDTAKGML-------PDPKNTHIVISWMIAQTVTAVAGL-T 227 Query: 121 GGPVDLIKIRLQMQT 135 P D ++ R+ MQ+ Sbjct: 228 SYPFDTVRRRMMMQS 242 Score = 30.8 bits (68), Expect = 0.49 Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 7/52 (13%) Query: 17 AASVIVGHPLDTVKTRLQAGVG-------YGNTLSCIRVVYRRESMFGFFKG 61 A + + +P DTV+ R+ G Y TL C R + R E FFKG Sbjct: 222 AVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKG 273 Score = 26.9 bits (58), Expect = 7.1 Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 7 EDFAAGWIGGAASVIVGHPLDTVKTRLQ---------AGVGYGNTLSCIRVVYRRESMFG 57 +DF AG + A S P++ VK LQ A Y + C+ + + + + Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69 Query: 58 FFKG 61 F++G Sbjct: 70 FWRG 73 >gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens] Length = 301 Score = 51.2 bits (121), Expect = 4e-07 Identities = 40/128 (31%), Positives = 58/128 (45%), Gaps = 7/128 (5%) Query: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVG-YGNTLSCIRVVYRRESMFGFFKGMSFPL 66 D AG GG A V+ G P DT+K ++Q Y C Y + GF+KG S L Sbjct: 12 DLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPAL 71 Query: 67 ASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDL--LLASMVAGVVSVGLGGPV 124 + NSV+F + Q+ + + + +A LSDL A A + + P Sbjct: 72 IANIAENSVLFMCYGFCQQVVRKVAGLDKQAK----LSDLQNAAAGSFASAFAALVLCPT 127 Query: 125 DLIKIRLQ 132 +L+K RLQ Sbjct: 128 ELVKCRLQ 135 Score = 40.8 bits (94), Expect = 5e-04 Identities = 37/147 (25%), Positives = 60/147 (40%), Gaps = 15/147 (10%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQA----------GVGYGNTLSCIRVVYRRESM 55 L++ AAG A + +V P + VK RLQ S I+ + R++ Sbjct: 107 LQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGP 166 Query: 56 FGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGV 115 GF+ G+S L FG + ++ F + R + P L+L+ V G+ Sbjct: 167 LGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVP-----LMLSGGVGGI 221 Query: 116 VSVGLGGPVDLIKIRLQMQTQPFRDGG 142 PVD IK R+Q+ + + G Sbjct: 222 CLWLAVYPVDCIKSRIQVLSMSGKQAG 248 Score = 27.3 bits (59), Expect = 5.5 Identities = 16/80 (20%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRV---VYRRESMFGFFKGMSFPLA 67 +G +GG + +P+D +K+R+Q G IR V + E + + G+ + Sbjct: 215 SGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMI 274 Query: 68 SIAVYNSVVFGVFSNTQRFL 87 N +F + +++ + Sbjct: 275 RAFPANGALFLAYEYSRKLM 294 >gi|13775208 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 [Homo sapiens] Length = 315 Score = 50.4 bits (119), Expect = 6e-07 Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 15/137 (10%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYG-------NTLSCIRVVYRRESMFGF 58 L + A+G GA S+ V +PLD +TRL +G G CI + + + + G Sbjct: 126 LANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGL 185 Query: 59 FKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSV 118 ++G + I VY + FG + + L +P+ +P L +A +V + Sbjct: 186 YQGFGVSVQGIIVYRASYFGAYDTVKGLLP-----KPKKTP--FLVSFFIAQVVTTCSGI 238 Query: 119 GLGGPVDLIKIRLQMQT 135 L P D ++ R+ MQ+ Sbjct: 239 -LSYPFDTVRRRMMMQS 254 Score = 34.3 bits (77), Expect = 0.045 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGVG-----YGNTLSCIRVVYRRESMFGFFK 60 L F + S I+ +P DTV+ R+ G Y TL C +Y+ E + FF+ Sbjct: 223 LVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFR 282 Query: 61 G 61 G Sbjct: 283 G 283 >gi|21361103 solute carrier family 25, member 12 [Homo sapiens] Length = 678 Score = 49.7 bits (117), Expect = 1e-06 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 16/134 (11%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQAGVG---------YGNTLSCIRVVYRRESMFGFF 59 F G + GA +P+D VKTR+Q G Y N+ C + V R E FG + Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 60 KGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVG 119 +G+ L +A ++ V + ++ P L +LA AG V Sbjct: 390 RGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP-------LPAEVLAGGCAGGSQVI 442 Query: 120 LGGPVDLIKIRLQM 133 P++++KIRLQ+ Sbjct: 443 FTNPLEIVKIRLQV 456 Score = 47.4 bits (111), Expect = 5e-06 Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 10/125 (8%) Query: 11 AGWIGGAASVIVGHPLDTVKTRLQAG--VGYGNTLSCIRVVYRRESMFGFFKGMSFPLAS 68 AG G + VI +PL+ VK RLQ + G +S + V+ R +FG +KG Sbjct: 432 AGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVL-RDLGIFGLYKGAKACFLR 490 Query: 69 IAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIK 128 ++++ F V+++ + L+ G +LL A +AGV + L P D+IK Sbjct: 491 DIPFSAIYFPVYAHCKLLLADEN-GHVGGL------NLLAAGAMAGVPAASLVTPADVIK 543 Query: 129 IRLQM 133 RLQ+ Sbjct: 544 TRLQV 548 Score = 37.0 bits (84), Expect = 0.007 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 10 AAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNT-----LSCIRVVYRRESMFGFFKGMSF 64 AAG + G + + P D +KTRLQ G T + C R + R E F+KG Sbjct: 523 AAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKG--- 579 Query: 65 PLASIAVYNSVVFGVFSNTQRFLSQ 89 A+ +S FGV T L + Sbjct: 580 -TAARVFRSSPQFGVTLVTYELLQR 603 >gi|157388925 solute carrier family 25, member 38 [Homo sapiens] Length = 304 Score = 49.7 bits (117), Expect = 1e-06 Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 16/134 (11%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQA------GVGYGNTLSCIRVVYRRESMFGFF 59 ++ F G I G S ++ PLD +KTRLQ G L+ + V R ES+ G + Sbjct: 28 IKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDHGSRRVGMLAVLLKVVRTESLLGLW 87 Query: 60 KGMSFPLASIAVYNSVVFG-VFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSV 118 KGMS + + FG ++S Q FL H PP L ++L V V Sbjct: 88 KGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGH--------PPTALESVMLGVGSRSVAGV 139 Query: 119 GLGGPVDLIKIRLQ 132 + P+ +IK R + Sbjct: 140 CM-SPITVIKTRYE 152 Score = 42.4 bits (98), Expect = 2e-04 Identities = 33/127 (25%), Positives = 62/127 (48%), Gaps = 7/127 (5%) Query: 25 PLDTVKTRLQAG-VGYGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNT 83 P+ +KTR ++G GY + + +R +Y E G F G++ L A + S ++ +F N Sbjct: 143 PITVIKTRYESGKYGYESIYAALRSIYHSEGHRGLFSGLTATLLRDAPF-SGIYLMFYNQ 201 Query: 84 QRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQTQPFRDGGE 143 + + H + P S + A ++A +V+ P D+IK +Q+ F+ G+ Sbjct: 202 TKNIVPHDQVDATLIPITNFSCGIFAGILASLVT----QPADVIKTHMQLYPLKFQWIGQ 257 Query: 144 HRMTTVF 150 +T +F Sbjct: 258 -AVTLIF 263 Score = 26.9 bits (58), Expect = 7.1 Identities = 13/57 (22%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQA-GVGYGNTLSCIRVVYRRESMFGFFKG 61 + +F+ G G + +V P D +KT +Q + + + ++++ + GFF+G Sbjct: 218 ITNFSCGIFAGILASLVTQPADVIKTHMQLYPLKFQWIGQAVTLIFKDYGLRGFFQG 274 >gi|186928856 solute carrier family 25, member 19 [Homo sapiens] Length = 320 Score = 48.5 bits (114), Expect = 2e-06 Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 6/128 (4%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQAGVG---YGNTLSCIRVVYRRESMFGFFKGMSFP 65 F G + + + HP+D ++TR A Y + +YR E F+KG++ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVD 125 L +I Y + F +S+ + ++ P LL AGV+S L P+D Sbjct: 182 LIAIFPYAGLQFSCYSSLKHL---YKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLD 238 Query: 126 LIKIRLQM 133 L K RLQ+ Sbjct: 239 LFKKRLQV 246 Score = 38.5 bits (88), Expect = 0.002 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGV------------GYGNTLSCIRVVYRRE 53 L++ G G S + +PLD K RLQ G Y + C + V ++E Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276 Query: 54 SMFGFFKGMSFPLASIAVYNSVVF 77 GFFKG+S L A+ +F Sbjct: 277 GALGFFKGLSPSLLKAALSTGFMF 300 Score = 28.5 bits (62), Expect = 2.5 Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 102 TLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQ 134 T + +A V+G+V+ L P D+IKIR Q+Q Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQ 46 >gi|186928860 solute carrier family 25, member 19 [Homo sapiens] Length = 320 Score = 48.5 bits (114), Expect = 2e-06 Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 6/128 (4%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQAGVG---YGNTLSCIRVVYRRESMFGFFKGMSFP 65 F G + + + HP+D ++TR A Y + +YR E F+KG++ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVD 125 L +I Y + F +S+ + ++ P LL AGV+S L P+D Sbjct: 182 LIAIFPYAGLQFSCYSSLKHL---YKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLD 238 Query: 126 LIKIRLQM 133 L K RLQ+ Sbjct: 239 LFKKRLQV 246 Score = 38.5 bits (88), Expect = 0.002 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGV------------GYGNTLSCIRVVYRRE 53 L++ G G S + +PLD K RLQ G Y + C + V ++E Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276 Query: 54 SMFGFFKGMSFPLASIAVYNSVVF 77 GFFKG+S L A+ +F Sbjct: 277 GALGFFKGLSPSLLKAALSTGFMF 300 Score = 28.5 bits (62), Expect = 2.5 Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 102 TLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQ 134 T + +A V+G+V+ L P D+IKIR Q+Q Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQ 46 >gi|186928858 solute carrier family 25, member 19 [Homo sapiens] Length = 320 Score = 48.5 bits (114), Expect = 2e-06 Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 6/128 (4%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQAGVG---YGNTLSCIRVVYRRESMFGFFKGMSFP 65 F G + + + HP+D ++TR A Y + +YR E F+KG++ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 66 LASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVD 125 L +I Y + F +S+ + ++ P LL AGV+S L P+D Sbjct: 182 LIAIFPYAGLQFSCYSSLKHL---YKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLD 238 Query: 126 LIKIRLQM 133 L K RLQ+ Sbjct: 239 LFKKRLQV 246 Score = 38.5 bits (88), Expect = 0.002 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQAGV------------GYGNTLSCIRVVYRRE 53 L++ G G S + +PLD K RLQ G Y + C + V ++E Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276 Query: 54 SMFGFFKGMSFPLASIAVYNSVVF 77 GFFKG+S L A+ +F Sbjct: 277 GALGFFKGLSPSLLKAALSTGFMF 300 Score = 28.5 bits (62), Expect = 2.5 Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 102 TLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQ 134 T + +A V+G+V+ L P D+IKIR Q+Q Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQ 46 >gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo sapiens] Length = 325 Score = 48.5 bits (114), Expect = 2e-06 Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 20/138 (14%) Query: 15 GGAASVIVGH---PLDTVKTRLQA----------GVGYGNTLSCIRVVYRRESMFGFFKG 61 GG AS++ P+D KTRLQ + Y + + + E + + G Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106 Query: 62 MSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLG 121 ++ L A Y ++ G++ + +R E TL ++ +V+GV+S + Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLF-------VERLEDETLLINMICGVVSGVISSTIA 159 Query: 122 GPVDLIKIRLQMQTQPFR 139 P D++KIR+Q Q F+ Sbjct: 160 NPTDVLKIRMQAQGSLFQ 177 Score = 37.0 bits (84), Expect = 0.007 Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 8/131 (6%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQA--GVGYGNTLSCIRVVYRRESMFGFFKGMS 63 L + G + G S + +P D +K R+QA + G+ + +Y++E G ++G+ Sbjct: 142 LINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVV 201 Query: 64 FPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGP 123 A+ V V+ T++ L T+ ++S G+ P Sbjct: 202 PTAQRAAIVVGVELPVYDITKKHLIL------SGMMGDTILTHFVSSFTCGLAGALASNP 255 Query: 124 VDLIKIRLQMQ 134 VD+++ R+ Q Sbjct: 256 VDVVRTRMMNQ 266 Score = 35.8 bits (81), Expect = 0.015 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 7/92 (7%) Query: 1 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRL---QAGVG----YGNTLSCIRVVYRRE 53 MG L F + + G A + +P+D V+TR+ +A VG Y T+ I +++ E Sbjct: 231 MGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHE 290 Query: 54 SMFGFFKGMSFPLASIAVYNSVVFGVFSNTQR 85 F +KG + +N + F + +R Sbjct: 291 GFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322 >gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo sapiens] Length = 322 Score = 48.5 bits (114), Expect = 2e-06 Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 20/138 (14%) Query: 15 GGAASVIVGH---PLDTVKTRLQA----------GVGYGNTLSCIRVVYRRESMFGFFKG 61 GG AS++ P+D KTRLQ + Y + + + E + + G Sbjct: 44 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 103 Query: 62 MSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLG 121 ++ L A Y ++ G++ + +R E TL ++ +V+GV+S + Sbjct: 104 IAPALLRQASYGTIKIGIYQSLKRLF-------VERLEDETLLINMICGVVSGVISSTIA 156 Query: 122 GPVDLIKIRLQMQTQPFR 139 P D++KIR+Q Q F+ Sbjct: 157 NPTDVLKIRMQAQGSLFQ 174 Score = 37.0 bits (84), Expect = 0.007 Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 8/131 (6%) Query: 6 LEDFAAGWIGGAASVIVGHPLDTVKTRLQA--GVGYGNTLSCIRVVYRRESMFGFFKGMS 63 L + G + G S + +P D +K R+QA + G+ + +Y++E G ++G+ Sbjct: 139 LINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVV 198 Query: 64 FPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGP 123 A+ V V+ T++ L T+ ++S G+ P Sbjct: 199 PTAQRAAIVVGVELPVYDITKKHLIL------SGMMGDTILTHFVSSFTCGLAGALASNP 252 Query: 124 VDLIKIRLQMQ 134 VD+++ R+ Q Sbjct: 253 VDVVRTRMMNQ 263 Score = 35.8 bits (81), Expect = 0.015 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 7/92 (7%) Query: 1 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRL---QAGVG----YGNTLSCIRVVYRRE 53 MG L F + + G A + +P+D V+TR+ +A VG Y T+ I +++ E Sbjct: 228 MGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHE 287 Query: 54 SMFGFFKGMSFPLASIAVYNSVVFGVFSNTQR 85 F +KG + +N + F + +R Sbjct: 288 GFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319 >gi|58197562 solute carrier family 25, member 30 [Homo sapiens] Length = 291 Score = 48.1 bits (113), Expect = 3e-06 Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 17/151 (11%) Query: 1 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAG----------VGYGNTLSCIRVVY 50 M + + F G + + P+D KTRLQ + Y L + + Sbjct: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60 Query: 51 RRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLAS 110 R E + + G++ + A Y ++ G + + +R + PE TL ++ Sbjct: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIER----PE---DETLPINVICG 113 Query: 111 MVAGVVSVGLGGPVDLIKIRLQMQTQPFRDG 141 +++GV+S + P D++KIR+Q Q+ + G Sbjct: 114 ILSGVISSTIANPTDVLKIRMQAQSNTIQGG 144 Score = 42.4 bits (98), Expect = 2e-04 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%) Query: 12 GWIGGAASVIVGHPLDTVKTRLQAGVG--YGNTLSCIRVVYRRESMFGFFKGMSFPLASI 69 G + G S + +P D +K R+QA G + +Y++E G +KG+S Sbjct: 113 GILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRA 172 Query: 70 AVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIKI 129 A+ V V+ T++ L T+ L+S G+ PVD+++ Sbjct: 173 AIVVGVELPVYDITKKHLIL------SGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRT 226 Query: 130 RLQMQTQPFRDG 141 R+ M + RDG Sbjct: 227 RM-MNQRVLRDG 237 Score = 37.4 bits (85), Expect = 0.005 Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Query: 1 MGSFQLEDFAAGWIGGAASVIVGHPLDTVKTRLQAG--------VGYGNTLSCIRVVYRR 52 MG F + + G A + +P+D V+TR+ GY TL C+ ++ Sbjct: 196 MGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKN 255 Query: 53 ESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQR 85 E F +KG + +N + F + ++ Sbjct: 256 EGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288 >gi|13259541 uncoupling protein 2 [Homo sapiens] Length = 309 Score = 48.1 bits (113), Expect = 3e-06 Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 23/149 (15%) Query: 15 GGAASV--IVGHPLDTVKTRLQ------------AGVGYGNTLSCIRVVYRRESMFGFFK 60 G AA + ++ PLDT K RLQ A Y + I + R E + Sbjct: 21 GTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYN 80 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 G+ L + SV G++ + ++F ++ G AS + LLA G ++V + Sbjct: 81 GLVAGLQRQMSFASVRIGLYDSVKQFYTK---GSEHAS----IGSRLLAGSTTGALAVAV 133 Query: 121 GGPVDLIKIRLQMQTQPFRDGGEHRMTTV 149 P D++K+R Q Q + GG +TV Sbjct: 134 AQPTDVVKVRFQAQAR--AGGGRRYQSTV 160 Score = 35.8 bits (81), Expect = 0.015 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTR-LQAGVG-YGNTLSCIRVVYRRESMFGFFKGMSFPL 66 F + + G + ++ P+D VKTR + + +G Y + C + ++E F+KG Sbjct: 218 FTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSF 277 Query: 67 ASIAVYNSVVFGVFSNTQRFL 87 + +N V+F + +R L Sbjct: 278 LRLGSWNVVMFVTYEQLKRAL 298 >gi|21314739 solute carrier family 25, member 32 [Homo sapiens] Length = 315 Score = 46.6 bits (109), Expect = 9e-06 Identities = 31/134 (23%), Positives = 64/134 (47%), Gaps = 12/134 (8%) Query: 7 EDFAAGWIGGAASVIVGHPLDTVKTRLQAGVG------YGNTLSCIRVVYRRESMFGFFK 60 E+ AG GG S + HPLD VK R G Y L C+ +++ + + G ++ Sbjct: 24 ENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQ 83 Query: 61 GMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGL 120 G++ + + + F ++ + + ++ R EA ++ L+++ AG +++ + Sbjct: 84 GVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEA------TEYLVSAAEAGAMTLCI 137 Query: 121 GGPVDLIKIRLQMQ 134 P+ + K RL +Q Sbjct: 138 TNPLWVTKTRLMLQ 151 Score = 36.2 bits (82), Expect = 0.012 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Query: 19 SVIVGHPLDTVKTRLQ-AGVGYGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVF 77 +V +P V+ RLQ + Y + I +R+E + GF+KG++ L + + F Sbjct: 238 AVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITF 297 Query: 78 GVFSNTQRFL 87 V+ N FL Sbjct: 298 VVYENVSHFL 307 >gi|13899342 solute carrier [Homo sapiens] Length = 315 Score = 46.6 bits (109), Expect = 9e-06 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 10/124 (8%) Query: 12 GWIGGAASVIVGHPLDTVKTRLQAGVG---YGNTLSCIRVVYRRESMFGFFKGMSFPLAS 68 G + G V P+D KTRLQ G Y + C+ R E FG ++G + L Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTL 74 Query: 69 IAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLIK 128 + ++ +R L E R L +LA AG+ V + P++++K Sbjct: 75 VTPEKAIKLAANDFFRRLLM-------EDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLK 127 Query: 129 IRLQ 132 I+LQ Sbjct: 128 IQLQ 131 Score = 37.4 bits (85), Expect = 0.005 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 9 FAAGWIGGAASVIVGHPLDTVKTRLQA---GVG---YGNTLSCIRVVYRRESMFGFFKGM 62 F +G + G+ + + PLD +KTR+Q G+G Y C R ++ +E F KG Sbjct: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA 284 Query: 63 SFPLASIAVYNSVVFGVF 80 IA + GV+ Sbjct: 285 GCRALVIAPLFGIAQGVY 302 Score = 29.3 bits (64), Expect = 1.4 Identities = 17/82 (20%), Positives = 38/82 (46%), Gaps = 6/82 (7%) Query: 51 RRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLAS 110 R + + G ++G+ L ++ + F +F+N G E + + + ++ Sbjct: 175 RTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNL------GFNELAGKASFAHSFVSG 228 Query: 111 MVAGVVSVGLGGPVDLIKIRLQ 132 VAG ++ P+D++K R+Q Sbjct: 229 CVAGSIAAVAVTPLDVLKTRIQ 250 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.140 0.430 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,249,738 Number of Sequences: 37866 Number of extensions: 243941 Number of successful extensions: 870 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 62 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 555 Number of HSP's gapped (non-prelim): 203 length of query: 157 length of database: 18,247,518 effective HSP length: 94 effective length of query: 63 effective length of database: 14,688,114 effective search space: 925351182 effective search space used: 925351182 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.