Guide to the Human Genome
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Search of human proteins with 221136821

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221136821 de-etiolated 1 isoform 2 [Homo sapiens]
         (550 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33354283 de-etiolated 1 isoform 1 [Homo sapiens]                  1129   0.0  
gi|221136821 de-etiolated 1 isoform 2 [Homo sapiens]                 1129   0.0  
gi|24430139 RNA polymerase II associated protein 1 [Homo sapiens]      38   0.027
gi|145309324 FH2 domain containing 1 [Homo sapiens]                    35   0.18 
gi|16554629 WD repeat domain 5 [Homo sapiens]                          33   0.52 
gi|16554627 WD repeat domain 5 [Homo sapiens]                          33   0.52 
gi|23199987 WD repeat domain 5B [Homo sapiens]                         32   1.2  
gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo sapi...    30   7.5  
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi...    30   7.5  
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi...    30   7.5  
gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]         30   7.5  

>gi|33354283 de-etiolated 1 isoform 1 [Homo sapiens]
          Length = 561

 Score = 1129 bits (2921), Expect = 0.0
 Identities = 550/550 (100%), Positives = 550/550 (100%)

Query: 1   MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPC 60
           MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPC
Sbjct: 12  MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPC 71

Query: 61  FLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRL 120
           FLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRL
Sbjct: 72  FLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRL 131

Query: 121 FERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESV 180
           FERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESV
Sbjct: 132 FERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESV 191

Query: 181 TPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIH 240
           TPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIH
Sbjct: 192 TPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIH 251

Query: 241 VFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLL 300
           VFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLL
Sbjct: 252 VFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLL 311

Query: 301 VYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPS 360
           VYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPS
Sbjct: 312 VYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPS 371

Query: 361 QASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQ 420
           QASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQ
Sbjct: 372 QASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQ 431

Query: 421 IQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPK 480
           IQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPK
Sbjct: 432 IQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPK 491

Query: 481 TCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYV 540
           TCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYV
Sbjct: 492 TCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYV 551

Query: 541 VNFHMRHCCT 550
           VNFHMRHCCT
Sbjct: 552 VNFHMRHCCT 561


>gi|221136821 de-etiolated 1 isoform 2 [Homo sapiens]
          Length = 550

 Score = 1129 bits (2921), Expect = 0.0
 Identities = 550/550 (100%), Positives = 550/550 (100%)

Query: 1   MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPC 60
           MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPC
Sbjct: 1   MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPC 60

Query: 61  FLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRL 120
           FLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRL
Sbjct: 61  FLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRL 120

Query: 121 FERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESV 180
           FERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESV
Sbjct: 121 FERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESV 180

Query: 181 TPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIH 240
           TPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIH
Sbjct: 181 TPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIH 240

Query: 241 VFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLL 300
           VFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLL
Sbjct: 241 VFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLL 300

Query: 301 VYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPS 360
           VYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPS
Sbjct: 301 VYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPS 360

Query: 361 QASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQ 420
           QASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQ
Sbjct: 361 QASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQ 420

Query: 421 IQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPK 480
           IQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPK
Sbjct: 421 IQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPK 480

Query: 481 TCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYV 540
           TCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYV
Sbjct: 481 TCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYV 540

Query: 541 VNFHMRHCCT 550
           VNFHMRHCCT
Sbjct: 541 VNFHMRHCCT 550


>gi|24430139 RNA polymerase II associated protein 1 [Homo sapiens]
          Length = 1393

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 5/96 (5%)

Query: 392  NFCDLFRNATLHSE-VQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRL---LGQ 447
            +F DL+ N   H E V F            +QRRF  T+  A +G H  A+R L   L Q
Sbjct: 1206 SFPDLYANFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGALRALSLPLTQ 1265

Query: 448  LPISAQSYSGSPYLDLSLFS-YDDKWVSVMERPKTC 482
            LP+S + Y+  P  +L+L   Y    V+   RP+ C
Sbjct: 1266 LPVSLECYTVPPEDNLALLQLYFRTLVTGALRPRWC 1301


>gi|145309324 FH2 domain containing 1 [Homo sapiens]
          Length = 1143

 Score = 35.0 bits (79), Expect = 0.18
 Identities = 30/138 (21%), Positives = 54/138 (39%), Gaps = 32/138 (23%)

Query: 265 LLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDGSAMAKRRFFQYF- 323
           LL  S     VQ+ ++  + N   +  +  ++ + L       ++DG    +   F  F 
Sbjct: 352 LLNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLK---ENIQRDGELCQQMEDFLQFA 408

Query: 324 -DQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENT 382
            ++LR+L  WK +L DE +  I +  ED  T+++                          
Sbjct: 409 IEKLRELECWKQELQDEAYTLIDFFCEDKKTMKL-------------------------- 442

Query: 383 SDELLELFENFCDLFRNA 400
            DE  ++F +FC  F  A
Sbjct: 443 -DECFQIFRDFCTKFNKA 459


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 33.5 bits (75), Expect = 0.52
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%)

Query: 51  TVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEY 87
           T+++ + PP    KFSP+G+Y +A + D T L++++Y
Sbjct: 208 TLIDDDNPPVSFVKFSPNGKYILAATLDNT-LKLWDY 243


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 33.5 bits (75), Expect = 0.52
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%)

Query: 51  TVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEY 87
           T+++ + PP    KFSP+G+Y +A + D T L++++Y
Sbjct: 208 TLIDDDNPPVSFVKFSPNGKYILAATLDNT-LKLWDY 243


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 14/37 (37%), Positives = 25/37 (67%), Gaps = 1/37 (2%)

Query: 51  TVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEY 87
           T+V+ + PP    KFSP+G+Y +  + D T L++++Y
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNT-LKLWDY 239


>gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo
           sapiens]
          Length = 337

 Score = 29.6 bits (65), Expect = 7.5
 Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 149 DDCRCVIVGSAAYLPDEPHPPFFEVYRNSESVTPNPRSPL 188
           D CRC    S A+ P +P    F   R S + +P P SP+
Sbjct: 272 DPCRC---SSTAHRPPQPRVCTFSPQRVSPTTSPRPASPV 308


>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score = 29.6 bits (65), Expect = 7.5
 Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 149 DDCRCVIVGSAAYLPDEPHPPFFEVYRNSESVTPNPRSPL 188
           D CRC    S A+ P +P    F   R S + +P P SP+
Sbjct: 272 DPCRC---SSTAHRPPQPRVCTFSPQRVSPTTSPRPASPV 308


>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score = 29.6 bits (65), Expect = 7.5
 Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 149 DDCRCVIVGSAAYLPDEPHPPFFEVYRNSESVTPNPRSPL 188
           D CRC    S A+ P +P    F   R S + +P P SP+
Sbjct: 272 DPCRC---SSTAHRPPQPRVCTFSPQRVSPTTSPRPASPV 308


>gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]
          Length = 2354

 Score = 29.6 bits (65), Expect = 7.5
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 19/86 (22%)

Query: 348  SEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQ 407
            S+D+    VTDP Q         +T + I+       E +++ +  CD F      SEV+
Sbjct: 1541 SDDIPLQLVTDPPQ---------LTVKDISCINT---ECIDIEDKSCDFFG-----SEVR 1583

Query: 408  FPCSASSNNFARQIQRRFKDTIINAK 433
              C AS+ +   Q +  FK  IIN K
Sbjct: 1584 CNCKASTPSMTNQCKETFK--IINRK 1607


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,503,216
Number of Sequences: 37866
Number of extensions: 896544
Number of successful extensions: 2400
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2390
Number of HSP's gapped (non-prelim): 16
length of query: 550
length of database: 18,247,518
effective HSP length: 107
effective length of query: 443
effective length of database: 14,195,856
effective search space: 6288764208
effective search space used: 6288764208
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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